Bioethics Research Library The Joseph and Rose Kennedy Institute of Ethics

bioethics.georgetown.edu

A Guide to the Archival Collection of

The Robert Cook-Deegan Human Genome Archive

Set 2

April, 2013

Bioethics Research Library

Joseph and Rose Kennedy Institute of Ethics

Georgetown University Washington, D.C. Overview

The Robert Cook-Deegan Human Genome Archive is founded on the bibliography of The Gene Wars: Science, Politics, and the Human Genome. The archive encompasses both physical and digital materials related to The Human Genome Project (HGP) and includes correspondence, government reports, background information, and oral histories from prominent participants in the project.

Hosted by the Bioethics Research Library at Georgetown University the archive is comprised of 20.85 linear feet of materials currently and is expected to grow as new materials are processed and added to the collection. Most of the materials comprising the archive were obtained between the years 1986 and 1994. However, several of the documents are dated earlier.

Introduction

This box listing was created in order to assist the Bioethics Research Library in its digitization effort for the archive and is being shared as a resource to our patrons to assist in their use of the collection.

The archive consists of 44 separate archive boxes broken down into three separate sets. Set one is comprised of nine boxes, set two is comprised of seven boxes, and set three is comprised of 28 boxes. Each set corresponds to a distinct addition to the collection in the order in which they were given to the library. No value should be placed on the importance of any given set, or the order the boxes are in, as each was accessed, processed, and kept in the order in which they were received.

Every effort was made to maintain the integrity of the boxes in the order they were processed. Except in cases of damage and materials that were oversized that required special processing the materials have been kept in the exact order that the Bioethics Research Library received them in.

In addition, every effort was made to be faithful to the headings and labeling of the materials in the collection. If a folder, binder, or packet did not have a specific label identifying it generic labels were added to assist in processing. For example, a folder with no identifying label is identified as Folder 1 in the box listing. Any additional unlabeled folders in the same box follow a sequential pattern, i.e. Folder 2, Folder 3, etc. Each individual box holds to this pattern. This means there are multiple folders with the heading of Folder 1. Thus when citing an unlabeled item it is important to use the exact set and box number in order to locate that item. For example, Set 2, Box 6, Folder 2. Also note that every effort was made to properly title individual items. In many cases, especially with correspondence and memos, there is not a specific title associated with that item. For clarity sakes these items are labeled as being from a specific person or department to another specific person or department. In cases where no title or author was present the first line of the document was used as a title.

Each set has a separate box listing. It is expected that researchers and scholars using the collection will need to search in each set’s listing in order to locate relevant materials. Each set is completely text searchable to aid in this process. It is highly suggested that researcher use the find feature (control + f in most applications) in order to aid in the use of the box listing. Each set’s box listing comprises dozens of pages and in the case of set three the document alone is 157 pages long.

A presence for the archive has been established on the Bioethics Research Library and can be accessed by visiting https://bioethics.georgetown.edu/library-materials/digital-collections/robert- cook-deegan-human-genome-archive/

On this page you will find links to the full version of The Gene Wars, information linking to other websites that are working on preserving the history of the Human Genome Project, and links to digital reproductions of items from the collection created by the Bioethics Research Library.

A permanent link to this series of guides will also be maintained on Digital Georgetown:

Set 1 - http://hdl.handle.net/10822/708922

Set 2 - http://hdl.handle.net/10822/708923

Set 3 - http://hdl.handle.net/10822/708925

Updated April 17, 2014 CNN Acknowledgements

This guide would not have been possible without the significant assistance of several people.

First and foremost is Laura Ruth Barry whose able support, creativity and tireless efforts in wrangling both the physical collection and the data to create this guide cannot properly be conveyed in words.

Georgetown University students were integral in processing the materials on an item level basis. Jennifer Young, Joseph Wiedemer, Jade Walsh, Rebecca Kruser, Ta-Chueh Melody Hsu, Mary Laura Scalise, Rachel Cox, and John Sperry Nickerson. Without their assistance this project would have been stuck in neutral.

Anita Nolen, former archivist at the Bioethics Research Library, who first received and accessed the materials 20 years ago when they were first donated. She left the collection in such amazing shape that starting the process of digitizing and making the collection available to a larger audience was considerably eased. She also let a young preservationist pick her brain and play in her toy box. It was greatly appreciated.

Mark Hakkarinen who listened, advised, and help push on days when the work seemed overwhelming.

Martina Darragh, Patty Martin, and Roxie France-Nurriden, my “team” (which should really read that I am part of their team), not enough can be said for all the patience, teaching, and support you have offered me. Thank you.

Of course I’d also like to thank Dr. Robert Cook-Deegan who answered innumerable questions, made invaluable suggestions, and showed flexibility (and still does so) in how to approach the project.

Last, but not least, I would like to thank all my former and current colleagues at the Kennedy Institute of Ethics and Bioethics Research Library for creating an atmosphere where knowledge and the preservation and access to that knowledge is always strived for. I am not sure where else in the world where so many different people consistently strive to ensure that knowledge is shared freely and without concern of who benefits most from that information. It is truly inspiring.

Thank you all,

Nat Norton

4/10/2014

The Robert Cook-Deegan Human Genome Project Archive Set 2

Box Listing

Cook-Deegan Box 1/7

Folder 1 - FADRF ● The New York Times Magazine December 13, 1987 ● Copy of page from The Economist June 25, 1988. “Genes rampant” No author. ● Magazine- California July 1988 ● Newspaper cutout- Washington Post July 21, 1987. “In gene mapping, an opening gambit” by Larry Thomspon ● Copy of page from The New York Times November 4, 1986. “Big money and science” by Malcolm W. Browne ● Magazine- Omni- June 1990. Attached is business card from Catherine Spencer of Omni ● Magazine- Smithsonian February 1990 ● Magazine- The Economist 30 April- 6 May 1988

Folder 2 - News coverage other than Wash Post and NYT ● Cutout from Wall Street Journal- No date. “Genetic map that could speed diagnosis of inherited disease touches off dispute” by David Stipp ● Cutout from The Christian Science Monitor September 9, 1987. “Reading the human Rosetta stone” by Robert C. Cowen ● Cutout from Miami Herald March 2, 1988. “Gene-mapping plan sparks political battle” by Larry Thompson ● Cutout from San Francisco Examiner January 18, 1989. “Winning public support” by Sally Lehrman ● Magazine – Insight May 11, 1987 ● Copy of page from Science Magazine January 13, 1989. “Genome project underway, at last” by Leslie Roberts ● Cutout from The San Diego Union December 22, 1986. “Biologists aim to catalogue full genetic code” ● Copy of page from Insight June 15, 1987 “Money for genomes” by CD ● Cutout from The Boston Globe October 8, 1987. “Mass. firm’s genetic map said to aid health care” by Richard Saltus ● Cutout from Seattle Times June 15, 1987 “Mapping life’s blueprint” by Larry Thompson ● Cutout from Chronicle of Higher Education September 2, 1987 “Spending bills top big workload facing post-vacation congress” No author ● Copy of page from Insight May 11, 1987. “Mapping the genes, inside and out” No author. ● Magazine- Reprinted from The Atlanta Journal and The Atlanta Constitution “Shaking the family tree: life, death and DNA” ● Magazine- Time March 20, 1989 ● Copy of page from The Wall Street Journal March 16, 1989 “Chromosome cartography” No author ● Cutout from The Washington Times December 28, 1988. “Care for victims a costly effort” by Joyce Price ● Cutout from Buffalo News December 28, 1986 “A catalogue of genetic code is sought” by Gayle Golden Cook-Deegan Box 1/7

● Cutout from San Francisco Examiner-Chronicle January 15, 1989 “Biotech breeds hope and unease” by Sally Lehrman ● Cutout from San Jose Mercury News January 16, 1989 “How gene-mapping will boost industry” by Alex Barnum

Folder 3 - Issues in Science and Technology papers. Hood and Smith; Gilbert; Baltimore; Ayala Kirschstein reply; other responses ● “Genome sequencing: how to proceed” by Leroy Hood and Lloyd Smith. February 06, 1987 ● “Genome sequencing: creating a new biology for the twenty-first century” by Walter Gilbert February 4, 1987 ● “Genome sequencing: a small-science approach” by David Baltimore. February 4, 1987 ● “Two frontiers of human biology: what the sequence won’t tell us” by Francisco J. Ayala. February 5, 1987

Folder 4 - Other ● Letter from Jiayao Li to Jacqueline Courteau October 26, 1987. About activities in gene sequencing in China ○ Letter from Jiayao Li to Jacqueline Courteau. October 27, 1987. Attached is more materials ■ Document in Chinese ■ Handwritten document entitled Natl Med J China 63: 213. 1983. “Genetic susceptibility to esophageal cancer in LinXian Country” by Ding Jia Huan et al. ■ Another handwritten document entitled Nat Med J China 65: 404- 407, 1985 “Chromosome fragility in peripheral blood lymphocytes of 30 esophageal cancer patients” by Hu Nam et al. ■ Chinese document attached to above

● Letter from Nemat Hashem to CD November 10, 1987. Attached is form to review OTA documents ● Letter from Jeffrey T. Lutz to Jacqueline Courteau. July 27, 1987. About Naval Medical Research Unit ● Abstracts in Biocommerce Vol 10 No1 January 11, 1987 ● Letter from H. Magenschab to Jacqueline Courteau. July 17, 1987. Letter been passed on to Austrian authorities ● Letter from Jiayao Li to Jacqueline Courteau. July 17, 1987. Letter been passed to him because original person tried to contact in China. With Li’s business card. ● Document in Chinese from the Chinese Biochemical Journal Vol 2. No 4 Aug 1986 ● Document in Chinese, no date etc. in English ● Letter from Francis X. Cunningham to Jacqueline Courteau. August 11, 1987. Information about mapping and sequencing in Egypt Cook-Deegan Box 1/7

● Letter from Anne Irene Kvernmo to Jacqueline Courteau. August 19, 1987. Letter been forwarded to Trade Commission of Norway ● Letter from Jens Eikaas to OTA. Letter sent to Norwegian Embassy misrouted. ● Letter from Sverker Hogberg to Jacqueline Courteau. July 30, 1987. Attached is statement from Swedish Ministry of Health and Social Affairs ● Science and Government Report 5. August 1, 1987. “Science Attaches: the cast based in Washington” ● Letter from Bertil Wennergren to Jacqueline Courteau. October 18, 1987. Attached is information about genetic research in Sweden ● Letter from Jerry L. Hseuh to CD. October 10, 1989. About work of Fudan University ● Commission on Ethical Questions Concerning Biotechnology Established by the Norwegian Government report.

Folder 5 - NYT and Washington Post coverage ● NYT 10/08/87 “New map of genes may aid in fighting hereditary diseases” by Harold M. Schmeck Jr. ● WP 01/10/89. “$100 million sought for study of genes” by Larry Thompson ● WP 02/16/88. “Mapping the human genes” by Larry Thompson ● NTY 10/04/88 “DNA pioneer to tackle biggest gene project ever” by Harold M. Schmeck Jr. ● No source/9/27/88. “Gene pioneer will head mapping project” by Larry Thompson ● Washington Post- Health Section. 08/02/88 ● Washington Post – Health Section 05/03/88 ● WP 11/29/88 “Will Bush pay attention to science?” Philip J. Hilts ● NYT 3/27/87. “Deciphering the book of man” No author ● WP 09/14/87 “NIH’s doors opening to private companies” by Malcolm Gladwell ● Sealed envelope addressed to CD from D. McMullen ● WP 02/23/88 “The research budget” by Larry Thompson ● WP 2/17/86 “Entire organism’s genes mapped by scientists” by Philip J. Hilts ● WP 11/10/87 “Deciphering humanity’s genetic code” by Larry Thompson

Folder 6 - Congressional quarterly coverage All items below are from CQ ● September 17, 1988. “Congress clears labor-HHS spending bill” ● August 27, 1988 “Cautious lawmakers fret over biotech issues” ● August 13, 1988 “Labor-HHS conference ends; abortion issue still unsettled” ● August 6, 1988 “Patent-law exemption endorsed for gene-altered farm animals”

Folder 7 - Harvard Kennedy School Master’s thesis project ● “The Human Genome Project: What Approach Should the United States Take?” by Kenneth Jones April 12, 1988

Cook-Deegan Box 1/7

Folder 8 - International-Countries United Kingdom ● Nature Vol 323 16 October 1986. “Is Britain spending enough on science?” by John Irvine and Ben R. Martin ● Letter from Michael Probert to Jacqueline Courteau. July 29, 1987. Info about mapping and sequencing in the UK ● Nature Vol 326 March 12, 1987 “Brenner homes in on the human genome” by Joseph Palca ● Letter from D.J. Yarrow to CD. October 21, 1986. Thanking him for background info on OTA ● Letter from D.J. Yarrow to CD. January 20, 1987. List of work done in UK ● Letter from Michael Probert to Doug. January 9, 1987. More info about work done in UK ● List of inherited diseases mapping projects since 1985 in UK ● List of inherited diseases: molecular genetics current projects ● List of human genes mapping current projects ● List of human genes molecular genetics current projects ● List of human genes molecular genetics current projects ● Nature Vol 328 6 August 1987 “Going for broke” ● Nature Vol 326 12 March 1987 “Money to flow again at NIH, but how long will it last?” by Joseph Palca ● Abstracts in Biocommerce Vol 10, No 1 January 11, 1988 ● Letter from Michael Probert to Doug. December 14, 1987. Attached is Chapter 8 of draft OTA report on Mapping and Sequencing the Human Genome with revisions ● Letter from D.J. Yarrow to CD- December 22, 1987. Comments on draft report ● Nature Vol 322 31 July 1986 “No consensus on sequence” by Joseph Palca with handwritten notes ● Letter from J. Collins to CD. December 14, 1987. Wants to learn about stats and plans of Human Genome Initiative ● UK Human Genome Mapping Project April 1989

Folder 9 - Australia ● Letter from Joseph R. Hlubucek to CD- January 14, 1986. Attached is reply from National Health and Medical Research Council in Australia ● Letter from Joseph R. Hulbucek to CD- February 3, 1987. Attached is further information from Australia ● Computer printout list of project grants for years 86/87 ● Nature Vol 328 6 August 1987 “Putting more ‘I’ into Australia’s CSIRO” by Charles Morgan ● Letter from Paul van Belkom to Jacqueline Courteau. November 4, 1987. Answers to questions about gene mapping in Australia with attached information ● Copy of above ● Letter from Joe Hlubucek to CD- April 17, 1989. With Hlubucek business card. ○ Letter from CD to Federico Mayor. Feburary 16, 1989. About UNESCO meeting February 1989 ○ Copy of van Belkom letter with attached info Cook-Deegan Box 1/7

○ Letter from Joseph R. Hlubucek to CD- January 14, 1986. Enclosed is reply from National Health and Medical Research Council in Australia ○ Printout of project grants from above organization

Folder 10 - Belgium ● Letter from L. Arnould to CD. December 16, 1986. Who to contact about Belgian activities. ● Letter from A. Lafontaine to CD. June 26, 1987. His comments about mapping human genome ● Letter from Denis Dewez to Jacqueline Courteau. Information on Belgian activities from Embassy. Attached is list of programs supported by the Belgian fund for medical research

Folder 11 - Canada ● Letter from Jacqueline Courteau to Peter Winter. October 13, 1987. Questions about Canada’s policies/activities in human genome mapping and sequencing ● Letter from Francis M. Kinnelly to Jacqueline Courteau. July 27, 1987. Not have information at embassy in Ottawa ● Copy of page from The Chronicle of Higher Education. January 27, 1988. “Canada raises science funds $1.3 billion; ‘smoke and mirrors’, critics say” by Mark Gerson ● Letter from Laird Roe to CD. No date. Attached is Canadian suggestions for OTA report.

Folder 12 - Denmark ● Letter from Bent Skou to CD- November 5, 1986. Embassy received letter, Danish Board of Health will reply. Attached is second letter dated February 18, 1987 with more information ● Letter from Bent Skou to CD- April 15, 19897. Additional information ● Letter from Bent Skou to CD- March 30, 1987. Will not be able to attend OTA meeting. ● Letter from Bent Skou to Jacqueline Courteau. July 16, 1987. Forwarded letter to Board of Health. ● Letter from Jan Mohr to Jacqueline Courteau. August 19, 1987. Answers to questions about Danish activities. ● Copy of above., ● Letter from Jan Mohr to CD- December 20, 1987. Suggestions for OTA report\ ● Page of report with Mohr suggestions

Folder 13 - Eastern Europe and USSR ● Article. “BMFT evaluates results of subsidies for biotechnology projects” No author. Bon Technologie Nachrichten-Program Informationen. June 1, 1987 ● Copy of page from Nature Vol 330 17 December 1987. “US/Soviet science summit parlay in new spirit” by Joseph Palca Cook-Deegan Box 1/7

● Copy of page from Nature Vol 331 21 January 1988. “New agreement adds zest to US/Soviet exchange” by Joseph Palca. ● Article. Science and Technology. Europe and Latin America. “FRG institute examines east bloc advanced technology programs”. Das “Eureka” project osteuropas in German December 1986 ● Article. “Computers in Biotechnology”. Nauka I Zhizn No 5. May 1987 ● Article. “Statistical characteristics of primary functional regions of escherichia coli genome. Part 3. Computer recognition of coding regions” Molekulyarnaya Biologiya Vol 20, No 5. Sept-Oct 1986 ● Two pages with three different article abstracts. “Goals of biotechnology”, “Genetically engineered interferon” and “Scientific and technical cooperation in biotechnology” ● Article. “Research on GDR molecular biology institute”. Spectrum No. 3, 1987. Interview with Charles Coutelle, Astrid Speer and Hans-Dieter Hunger. ● Article. “Bacterial genome construction: new advances in genetic engineering” by V.V Sukhodolets. Genetika Vol 22, No 6. June 1986 ● Routing and transmittal slip with note to CD and business card of Konstantin G. Sryabin saying he want info on report ● Letter from A. Bayev to CD. March 31, 1989. Thanking him for receipt of OTA reports

Folder 14 - Finland ● Article. “Finland: 184 million markka biotechnology program 1998-1992) by Birgitta Jernvall Ingman. Hufvudstadsbladet January 31, 1987. ● Article. “Cell research center proposed to keep top scientists in Finland” by Juhani Aromaki. Helsingin Sanomat January 18, 1987. ● Handwritten notes with addresses of people to contact about Finland ● Letter from Albert de la Chapelle to Jacqueline Courteau. August 6, 1987. Information about gene mapping in Finland. ● Table. Rare recessive disorders that are more prevalent than elsewhere (about Finland ● While you were out slip. Marika Anderson from Finnish Embassy called. ● Letter from Albert de la Chapelle. November 25, 1986. Enclosed is information on gene mapping in Finland

Folder 15 - France ● While you were out slip ● Copy of pages from Biofuture June 1987. “The human genome project” by Lennart Philipson and John Tooze. ● Letter from Michel Bernon to Jacqueline Courteau. July 28, 1987. Receipt of letter, Ministry of Health contacted. ● Handwritten notes with address and info about French activities ● Letter from Michel Bernon to Jacqueline Courteau. September 1, 1987. Attached is answer to questions about human gene mapping and sequencing ● Article. “French find difficulties in Eureka funding” by P.K. Le Figaro July 12, 1987 Cook-Deegan Box 1/7

● Copy of page from The Scientist December 14, 1987. “Japan clouds view of French R&D” by Jeffrey Mervis. ● Empty envelope addressed to Jacqueline Courteau from French Embassy

Folder 16 - Federal Republic of Germany ● Letter from Jacqueline Courteau to Heinrich Klemenz. October 12, 1987. Clarifying details about last correspondence about German mapping and sequencing ● Handwritten notes about Klemenz ● Business card of Bernd-Uwe Jahn. Science Counselor Embassy of the Federal Republic of Germany ● Letter from Dieter Soll to Jacqueline Courteau. About who to contact for more info.

Folder 17 - Israel ● Handwritten notes ● Article. “Israeli research in high-protein wheat” by Massimo Crippa. Biotect Nov- Dec 1986 ● Copy of page from Nature Vol 327 June 18, 1987. “Great achievements, difficult times” No author. ● List of names entitled “Science in Israel” July 29, 1987. The Association for Science, Technology, Engineering and Public Policy” Washington, DC

Folder 18 - Switzerland ● Letter from Martin Buechi to Jacqueline Courteau. August 18, 1987. Enclosed is information asked for

Folder 19 - Italy ● Document in Italian dated February 27, 1987. From Francesco Pocchiari ● Article. “Italian research minister announces innovation center” by Paola De Paoli. Il Sole 24 Ore April 12, 1987 ● Copy of page from Nature Vol 326 23 April 1987. “Italy to map the human genome?” by Paola de Paoli ● Article. “Italian research ministry outlines CNR reform law” Ministero per il Coordnamento Della Ricerca Scientifica E Technologia October 8, 1986 ● Article with title cut off and no source by Paola de Paoli ● Article. “Reserchers interviewed on Italian biotechnology”. Biotec. May 1986 ● Handwritten notes ● Article in Italian with handwritten note attached ● Article. “Italy joins international gene mapping study” by Angelo Sommariva. Italia Oggi May 22, 1987 ● Article. “National program in advanced biotechnologies reviewed” ANSA June 10, 1987 ● Article. “CIPI approves Italian R&D project funding” Gazzetta Ufficiale Della Repubblica Italiana” No 215. September 15, 1987 Cook-Deegan Box 1/7

● Report- Institutions involved in the CNR strategic project of mapping and sequencing of the human genome subdivided according to operative lines ● Letter from Luigi Rossi Beranrdi to CD- Date is in Italian- 20 Lug. 1987. About invitation to attend first meeting of “Mapping the human genome” ● Letter from Emanuele Mannarino to Jacqueline Courteau. July 15, 1987. Attached information about mapping and sequencing genome in Italy.

Folder 20 - Latin America ● Letter from James W. Chamberlin to Jacqueline Courteau. August 14, 1987. About Brazilian efforts in human genome map ● Letter from Leroy C. Simpkins to Jacqueline Courteau. September 2, 1987. Attached is info about Mexico human genome mapping/sequencing ● Letter from Enrique Martin del Campo to Jacqueline Courteau. July 30, 1987. Attached is info about OAS work ● Letter from Robert G. Morris to Jacqueline Courteau. September 25, 1987. Information about biotechnology in Argentina will be sent ● Report- Biotechnology in Argentina ● Empty envelope addressed to Jacqueline Courteau from R. Morris ● Report- Documento Nro. 6. Proyectos Aprobados y Apoyos Otorgados 1984-1986 ● Letter from Victor L. Urquidi to Jacqueline Courteau. August 4, 1987. About work of El Colegio de Mexico ● Article. “Cross-breeding and genetic engineering produce minicows” by Javier Pichardini. Associated Press. February 23, 1988

Folder 21 - The Netherlands ● Handwritten notes about possible contacts ● Article- “Dutch scientists on biotech progress, commercial applications” De Volksrant November 3, 1986 ● Article. “Netherlands: genetic engineering requires tighter control” PT/Aktueel March 18, 1987

Cook-Deegan Box 2/7

Folder 1 - Database Matrix ● Report- Biotechnology: Nomenclature and Information Organization. Committee on Biotechnology Nomenclature and Information Organization, Board on Basic Biology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council. 1986 ● Executive Summary of above? ● Handwritten note labeled Matrix of Biological Knowledge Conference ● Workshop of the Matrix of Biological Knowledge Planned. Program details, faculty roster and invitation to invite more people March 11, 1987 ● Map of Stanford University campus and directions ● News from IntelliGenetics Vol 3 No 4, July 1987. With post-it notes to call Ginger Richardson

Folder 2 - Databases MIM ● Table 3.3 The Size of Human Genes- with notes, dollar figures, a note to Jacqueline and a timeline on back ● Torn while you were away slip with dollar figures on back

Folder 3 - Databases NLM ● Letter from Daniel Masys to Patricia Hoben. April 7, 1987. About draft plan for NLM. Attached is “Talking One Genetic Language: The Need for a National Biotechnology Information Center” ● Letter from Daniel Masys to Jaqueline Corteau. December 7, 1987. Attached is slide graphics of genomics databases. ● Handwritten notes entitled NLM and MB DBs ● Slide: NIH remote network connects ● Slide: Prototype NLM molecular biology information server ● Biotechnology Information: A Plan for the National Library of Medicine

Folder 4 -Databases NBRF-PIR ● “The protein identification resource and its application” by H.R. Chen and W.C. Barker. TIG August 1985 ● Protein Sequence Database Basic Information ● Letter from Winona C. Barder to CD. December 15, 1987. She wants to review entire report. ● Handwritten notes ● Project description. Ledley/Barker

Folder 5 - Databases Protein DataBank ● Handwritten notes- people involved with Protein DataBank ● The Protein Data Bank, by Enrique E. Abola, Francis C. Bernstein and Thomas F. Koetzle ● Letter from Frances C. Bernstein to Colleague. September 9, 1987. Request for data from Protein Data Bank been processed ● Introduction to the Protein Data Bank. June 1986 ● Protein Data Bank Newsletter Number 41, July 1987 ● Protein Data Bank Newsletter Number 42 October 1987 ● Introduction to the Protein Data Bank. June 1986 ● Protein Data Bank Newsletter. Number 39. January 1987 ● Protein Data Bank Newsletter. Number 43. January 1988

Cook-Deegan Box 2/7

Folder 6 - Databases Other ● Page from Computer-Readable Databases. Nucleotide Sequence Search System. ● Issues in Science and Technology. Volume 4 No 1. Fall 1987. With handwritten notes

Folder 7 - Databases Repositories ● American Type Culture Collection. NIH Repository of Human DNA Probes and Libraries. July 1987 ● American Type Culture Collection. Catalogue of Cell Line and Hybridomas. Fifth Edition, 1985 ● American Type Culture Collection. Catalogue of Bacteria, Phages, rDNA Vectors. 16th edition, 1985 ● Copy of page from Somatic Cell and Molecular Genetics. Vol 12, No 4. 1986. “The national institute of genetic medical sciences Human Genetic Mutant Cell Repository” with handwritten notes ● Copy of page from JAMA June 12, 1981. Vol 245, No 22. “Genetic cell repository: a major resource- and still growing” ● Information on National Institute of General Medical Sciences ● Copy of page from Human Genetics 1982 62: 291. The Human Genetic Mutant Cell Repository ● Copy of pages from Cytogenetics. Cell Genetics. 30 1981. “Breakpoint map of human translocation cell cultures available from the NIGM Human Genetic Mutant Cell Repository” by M.M. Aronson, R.C. Miller, W.W. Nichols, R.A. Mulivor, A.E. Greene and L.L. Coriell ● Page from unknown source. Letter from Lewis L. Coriell. “Cell repository”

Folder 8 - DNA Sequence Analysis- Software and Automation ● Copy of pages from Bio/Technology Vol 5. December 1987. “Robotics in the human genome project” ● Of URFs and ORFs: A Primer on How to Analyze Derived Amino Acid Sequences, by Russel F. Doolittle. 1986 ● Copy of page from unknown source. “Neural networks help determine DNA’s status” by Bob Brewin ● Same as above but computer printout with note from CD. ● Molecular Biology Data – Representation/Analysis by Computer. Grant application? ● Book review of “Of URFs and ORFs: A Primer on How to Analyze Derived Amino Acid Sequences” , written by Winona C. Barker. ● Copy of page from Genomics 1, 1987. “MAPMAKER: an interactive computer package for constructing primary genetic linkage maps for experimental and natural populations” by Eric S. Lander, Philip Green, Jeff Abrahamson, Aaron Barlow, Mark J. Daly, Stephen E. Lincoln, Lee Newburg ● Review of “Of URFs and ORFs: A Primer on How to Analyze Derived Amino Acid Sequences” written by Sydney Brenner in Nature Vol 329 8 October, 1987

Cook-Deegan Box 2/7

Folder 9 - Eureka ● Article- “Deutsche Bank criticizes Eureka objectives” Bonn Technologie Nachrichten-Management Information 29 June 1987 ● Article- “Eureka’s 108 projects survived” Paris Sciences and Techniques June 1987. ● Article- “ENA director assesses progress of Eureka program”. Media Deumila No 9. September 1987

Folder 10 - International Collaboration- Big Science ● Hearing before the Subcommittee on the International Scientific Cooperation of the Committee on Science, Space, and Technology U.S. House of Representatives 100th Congress First Session May 7, 1987- International Cooperation on the Superconducting Super Collider ● Letter from Carol E. Farnsworth to Patricia Hoben. December 21, 1987. Attached is list of new releases about mapping the human genome. ● Copy of page from Nature Vol 328 20 August 1987 “An ethical dilemma” by D.R. Forsdyke ● Copy of page from unknown source. “Grant committee accused of slowing AIDS research” by D.R. Forsdyke ● Copy of page from unknown source. January 4, 1988. “Money, science and the SSC” by Rep. Sherwood L. Bochlert. With handwritten note ● CRS Report for Congress: World Inventory of “Big Science” Research Instruments and Facilities by William C. Boesman. December 1986

Folder 11 - International Collaboration- Space and Geophysics ● Letter from Robert W. Smith to CD. July 10, 1987. Observations on Workshop on “Human Genetic Information and the Public Domain”. Attached to handwritten note about Robert W. Smith ● Copy of page from Nature Vol 329 29 October 1987 “Will Britain stay within CERN?” by John Maddox ● Memorandum of Understanding between the European Space Agency and the United States National Aeronautics and Space Administration ● Report on Possible Modes of International Cooperation for the Use of the Glomer Explorer by Herman Pollack. November 1, 1979

Folder 12 - International Collaboration – International Geophysical Year ● Copy of page from unknown source. “International Falls- International Joint Commission” ● Handwritten notes attached to “Beyond the Atmosphere: Early Years of Space Science” by Homer E. Newell ● The Library of Congress Computerized Catalogue printout – International Geophysical Year, requested by Jacqueline Courteau. 7/24/1987

Folder 13 - International Contract/Newmark ● Handwritten note with sections labeled Japanese efforts and German sections

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Folder 14 - International Contract- Peter Newmark ● Congress form- Individual Contractor’s Invoice filled out by Peter Newmark ● Draft letter from Jacqueline Courtaue to Peter Newmark. July 8, 1987. Enclosed is list of European scientists or administrators ● Proposal from Peter Newmark ● Letter from CD to Peter Newmark. June 9, 1987. Thanking him for replying for OTA request for proposals ● Letter from Jacqueline Courtaue to Peter Newmark. July 8, 1987. Enclosed is list of European scientists or administrators ● Statement of work ● Letter from Peter Newmark to CD. June 15, 1987. Asking for more info ● Letter from Jacqueline Courteau to Peter Newmark. September 3, 1987. Questions about his report ● Letter from Peter Newmark to Jacqueline Courteau. October 12, 1987. Answers to above questions ● Copy of above with finalized report attached ● “Mapping and Sequencing the Human Genome in Europe” by Peter Newmark. Draft report July 16, 1987

Folder 15 - International Efforts- Contacts-Correspondence ● Draft letter from Jacqueline Courteau to new OTA contacts. July 9, 1987 ● Draft letter from Jacqueline Courteau to contacts suggested by embassies. July 2, 1987 ● Letter from Jaqueline Courteau to Joseph R. Hlubucek. July 6, 1987. Follow up letter sent to embassy counselors who did reply ● Letter from CD to Christian Risch. October 22, 1986. Embassy letter/human gene mapping ● List of U.S. Science Attaches. Who they are and where posted ● Draft follow up letter to embassies. July 13, 1987 ● Letter from Jacqueline Courteau to Marika Andersson (Finland) asking for info ● Letter from Hassan El-Chawaby to CD- October 29, 1986 Egypt activities ● Letter from Marika Andersson to CD- December 1, 1986. she contacted Prof. Albert de la Chapelle ● Letter from Michel Bernon to CD- November 5, 1986. Forwarded request to French Ministry of Health

Folder 16 - International efforts- Hashem correspondence ● Letter from CD to Nemat Hashem. March 19, 1990. About a center in Egypt ● Letter from Nemat Hashem to CD- August 4, 1989. About center in Egypt at Ain- Shams University ● Project proposal from Nemat Hashem- “Establishment of a regional medical genetics center in Cairo, Egypt” Cook-Deegan Box 2/7

Folder 17 -International organizations- EMBO/EMBL ● Abstracts in Biocommerce Vol 10 No 1 January 11, 1988 ● The 1987-1990 Scientific Programme of the EMBL (SP87)

Folder 18 -International Organization OECD ● Letter from Bruna Teso to Jacqueline Courteau. August 6, 1987. No planned activities by OECD

Folder 19 - International Organizations- Other ● Copy of pages from unknown source- “European companies form research network to forge university-industry links” by David Dickson. No date ● Copy of page from Nature Vol 330 3 December 1987. “France prunes research spending but supports big science” by Peter Coles

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Folder 1 - Databases cont ● Draft program for First CODATA workshop on nucleic acid and protein sequence data May 1-6, 1987 ● Paperclipped documents with sticky note labeled “database duplicates” ○ Copy of pages from Nature Vol 327 11 June 1987 ○ Genatlas: a new data base for the human gene map by M. de Heaulme, M. Le Merrer and J. Frezal ○ Letter from Thomas F. Koetzle to Patricia J. Hoben May 7, 1987. Enclosed is newsletter ○ Copy of page from Nature Vol 327 28 May 1987 ○ List of databases to write letters to ○ EMBL/NIH Workshop- “Future Databases for Molecular Biology” February 25-27, 1987 ● Brochure for First CODATA workshop on nucleic acid and protein sequencing data May 3-6, 1987- call for abstracts ● Brochure about CODATA ● A different brochure about CODATA ● EMBL/NIH Workshop- “Future Databases for Molecular Biology” February 25- 27, 1987 ● Brochure for First CODATA workshop on nucleic acid and protein sequencing data May 3-6, 1987 ● Report- EMBL/NIH Workshop- Future Databases for Molecular Biology, February 25-27, 1987- different than above ● Report- EMBL/NIH Workshop- Future Databases for Molecular Biology, February 25-27, 1987 ● Informational book from Bio-Rad Laboratories to CD- a schedule of remaining sites

Folder 2 - DNA Databanks, international advisors for GenBank, EMBL, DDBJ. Front label says Databases-Individual

● List of international GenBank advisors 1987-1988 ● Letter from James C. Cassatt and Jane L. Peterson to CD. February 1, 1988. Inviting him to first meeting of the International Advisors for DNA Sequence Databanks held February 15-16, 1988 ● Pack of handwritten notes ● Business card from Minoru Kanehisa- Professor of Institute for Chemical Research Kyoto University ● Agenda of First International Meeting for DNA Sequencing Databanks ● Copy of above ● Blank general information form ● Milestones in the Collaboration of DNA Databases ● Summary- International Advisory Committee for DNA Sequence Databases

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Folder 3 - EMBL ● Copy of page from Nature Vol 325 29 January 1987 “EMBL database offer” by Rainer Stulich ● TIBTECH- December 1987 (Vol 5) “The Biocomputing Programme at EMBL”

Folder 4- European DBS ● Copy of page from Nature Vol 327 28 May 1987. “New protein database for Europe” ● HGM9 176 “Genatlas: a new database for the human genome” by M. Le Merrer, V. Bertrand, M.S. Baule, A. Marcuzzi, M.L. Briard, M. de Heulme, J. Frezal ● Genatlas: a new data base for the human gene map by M. de Heaulme, M. Le Merrer and J. Frezal ● Trends in BioTech Vol 5 No 5, May 1987. “European cooperation in biotechnology” by Kar-Heinz Narjes ● Copy of page from Nature Vol 327 28 May 1987. “New protein database for Europe”

Folder 5 -GenBank ● HHS News October 1, 1987. With handwritten names and phone numbers. About GenBank grant ● News from GenBank Vol 1 No 1 ● Agenda and papers from GenBank Advisors’ Meeting November 6, 1987 ● Handwritten notes ● List of GenBank advisors ● HHS News October 1, 1987. About GenBank grant ● News from IntelliGenetics Vol 3 No 6 November 1987 ● HHS News October 1, 1987. About GenBank grant. In different format than above. ● GenBank data request form ● Copy of page from Science 16 January 1987. GenBank status report ● Info sheet about GenBank ● Information about Genetic Sequence Databanks in unknown source ● Report- Sources of Data in the GenBank Database, by Christian Burks. Submitted to Proceedings of the First CODATA Workshop on Nucleic Acid and Protein Sequencing Data ● GenBank/DDBJ/EMBL Data Submission Form ● Letter from James C. Cassatt and Jane L. Peterson to GenBank Sponsors Forum. Next meeting April 26, 1988

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Folder 6 - HHMI incl. HGML ● HHMI Genonomics Project Newsletter #4 ● NLM/HHMI Collaborative network. Fig 5-3 ● Handwritten notes entitled HHMI’s Db Efforts ● Letter from Iva H. Cohen to Neil A. Holtzman. Information about Human Genome Mapping Library ● Human Gene Mapping Library User Documentation Howard Hughes Medical Institute. June 1987 ● Flowchart with handwritten notes showing Howard Hughes Medical Institute Genomics Resources ● While you were out slip with dollar figures on back

Folder 7 - Japanese DBS ● Partial List of Molecular Databases by C. Burks, LANL

Folder 8 - LIMB ● “Quality Control for a rapidly growing database” by Winona C. Barker, Lois T. Hunt and David G. George ● Computer list- all database entries? ● Computer list from LiMB database- all database entries?

Folder 9 - Acc.030- ● Archives National Reference Center for Bioethics Literature Accession Record. Accession No. 030. Data received 12 July 1990 ● Above is paperclipped to a copy of Tracy L. Friedman’s thesis entitled “The Science and Politics of the Human Genome Project” April 6, 1990

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Folder 1 - NSF ● Copy of page from Science Vol 238 “Document links NSF official to biotech firm” by Mark Crawford ● Program solicitation – The Biological Centers Program- 1987 ● Page from a transcript with handwritten note from Kathi to BCD ● Handwritten notes with title “NSF budgets”, “David Kingsbury” dated 10/8/1982 ● Copy of pages from the Federal Register Vol 52 No9 January 14, 1987 ● Copy of page from San Francisco Chronicle 10/16/1987 “Reagan biotech advisor faces criminal probe” by Elliot Diringer ● Copies of articles from unknown newspapers about biotech advisor probe – stamped October 16, 1987 ● Article- “Newspaper says White House advisor under investigation”. No author. AP ● Letter from CD and Patricia J. Hoben to Mary E. Clutter- December 4, 1986says enclosed is information on “Mapping of the Human Genome” and meeting with Kingsbury ● NSF Activities on Chromosome Mapping and Sequencing dated 1/1989 ● Copy of page from Science Vol 242 “NSF names first 11 science centers” ● Copy of page from Research News July 14, 1989. “Genome projects are growing like weeds” by Joseph Palca ● Letter from John H. Moore to James H. Scheuer July 28, 1988- about H.R. 4502- with highlighting ● Revised outline- NSF and the Support of Biology 1950-1975

Folder 2 - DOD ● Copy of pages from Technology in Society Vol 8 “The Department of Defense and biotechnology” by Thomas R. Dashiell” with handwritten notes ● Copy of above, no notes

Folder 3 - NEC National Numerical Database Advisory Board ● Letter from G.C. Carter to BCD- June 22, 1988- about BCD participation in meeting of Numerical Data Advisory Board of National Research Council- attached is agenda- highlighting ● Letter from G.C. Carter to BCD- July 13, 1988- thanking him for his participation- attached is copy of page from Nature Vol 333 June 23, 1988 “The pros and cons of freedom of access to human genome data” by J.P ● Copy of pages from The Scientist Vol 2 No 13, July 11, 1988- “Have the fraudbusters gone too far?” by Peter Gwynne ● Folder entitled Minutes of the Meeting of the Numerical Data Advisory Board July 7, 1988 ○ Inside is letter from Cynthia Carter to NDAB and its government-liason representatives USNC/CODATA and its ex-officio members other participants of the meeting of July 7-8, 1988- thanking participans

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Folder 4 - 10/19/89 NTL Coos Subcom/House SST ● News from Committee on Science, Space and Technology – U.S. House of Representatives- October 17, 1989- will hold hearing on the role of international cooperation in mapping the human genome ● Testimony of James D. Watson before the subcommittee October 19, 1989 ● Statement of Robert W. Wood – before same ● Testimony of George F. Cahill- before same ● HUGO News- “The Human genome organization: history, purposes, and membership”, By Victor A. McKusick ● Copy of pages from The New England Journal of Medicine April 6, 1990- “Mapping and sequencing the human genome” by Victor A. McKusick ● Copy of pages from Science Vol 210 November 21, 1980. “The 1980 Nobel Prize in chemistry” No author.

Folder 5 - Legislation 101st Congress ● Letter from BCD from Senator Albert Gore Jr. September 26, 1989–possible talking points for opening remarks for the Congressional Clearinghouse on the Future Luncheon September 26, 1989

Folder 6 - NLM ● Business card of Daniel R. Mass-Director, Lister Hill National Center for Biomedical Communications ● While you were out form with note to call BeL Ceja ● Ongoing Program Announcements- Vol 16, No 18, May 29, 1987 ● Copy of pages from The Washington Post April 9, 1986- “Spreading the medical word” by Joan McQueeney Mitric ● Copy of page from The New York Times November 14, 1986- “A library of medicine turns 150” by Barbara Gamarekian ● Copy of pages from unknown source- “Talking one genetic language: the need for a National Biotechnology Information Center” ● National Library of Medicine Fact Sheet January 1986 ● Handwritten note to BCD attached to “Biotechnology Information and the National Library of Medicine” backgrounder by Daniel M. Masys August 1986 ● National Library of Medicine – New Frontiers in Health Communication- Sesquicentennial 1836-1986 ● Letter from Donald A.B. Lindberg to BCD- thanking him for giving NLM opportunity to review Chapter 5 of OTA report on Mapping the Human Genome- attached is the chapter with revisions ● A copy of Chapter 5 ● National Library of Medicine Molecular Biology Information Science Projects- Current status as of 12/10/186 by D. Masys ● Biotechnology Information Update October 1988 ● National Library of Medicine Fact Sheet September 1989 ● National Library of Medicine Fact Sheet June 1989

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Folder 7 - McKusick Papers ● Paper clipped papers of computer code related to McKusick’s work ● Letter from Della Malone to CD April 12, 1988-enclosed as his request ● “Twenty-Five years in mammalian genetics and experimental mammalian genetics with particular reference to the gene map of mouse and man” by Victor A. McKusick and Thomas H. Roderick – Birth Defects: Original Article Series Vol 23, No 3 ● The Human Gene Map by Victor A. McKusick- October 1, 1987 ● “The Morbid Anatomy of the Human Genome: A Review of Gene Mapping in Clinical Medicine (First of Four parts)” by Victor A. McKusick. – The Johns Hopkins University School of Medicine, Vol 65, No 1 ● “The Morbid Anatomy of the Human Genome: A Review of Gene Mapping in Clinical Medicine (Second of Four parts)” by Victor A. McKusick. – The Johns Hopkins University School of Medicine, Vol 66, No 1 ● “The Morbid Anatomy of the Human Genome: A Review of Gene Mapping in Clinical Medicine (Third of Four parts)” by Victor A. McKusick. – The Johns Hopkins University School of Medicine, Vol 66, No 4 ● “The Morbid Anatomy of the Human Genome: A Review of Gene Mapping in Clinical Medicine (Last of Four parts)” by Victor A. McKusick. – The Johns Hopkins University School of Medicine, Vol 67 No 1

Folder 8 - Williamburg ESLI Mtg 2/90 ● Participants for ethics workshop February 5-6, 1990 ● Ethics working group ● Government representatives ● Program announcement- Ethical, Legal and Social Implications of the Human Genome Initiative ● “Eugenics and prenatal testing” by Ruth Hubbard- International Journal of Health Services, Vol 16, No 2, 1986 ● Letter to Members of the Ethics Working Group. No date. Ben Barnhart opinions on enlarging the Ethics Working Group. ■ Attached: handwritten note. ■ Letter from Ben Barnhart to Nancy. January 10, 1990. Mary Lou Perdue has agreed to be in working group. ■ Article: “Ethics and the Edges of Life” by Paul Ramsey. No date. ■ Interview with Arthur Caplan. No date. ■ Review of “Death by Choice” by Daniel C. Maguire. no date. No author. ■ Blurb about “Health/Medicine and the Faith Traditions: An Inquiry into Religion and Medicine” edited by Martin E. Marty and Kenneth I. Vaux. No date.

● Article from Detroit Free Press Magazine. “Daring to Known” by Susan Ager. November 20, 1988. ● “To test or not to test”. No author. Science January 5, 1990. Cook-Deegan Box 4/7

● “Who’s afraid of the human genome” by George J. Annas. Hastings Center Report July/August 1989. ● Letter from Nachama L. Wilker to BCD. January 10, 1990. Attached is a copy of the position papers of the Council for Responsible Genetics on the Human Genome Initiative and Genetic Discrimination ● “The oracle of DNA” by Nancy S. Wexler. No date. Unknown source. ● “Medical surveillance: biological, social, and ethical parameters”, by Sheldon W. Samuels. Journal of Occupational Medicine Vol 28 No 8 August 1986 ● “The potential impact of genetic testing on private insurance” by Robert Pokorski. November 30, 1989 ● “The new diagnosis” by Dorothy Nelkin and Laurence Tancredi. Phi Kappa Phi Journal Fall 1989 ● Letter to Participants in February 5-6 Ethics Workshop from Bettie J. Graham. January 4, 1990. ● Letter from Elke Jordan to BCD. December 28, 1989. About a workshop that will be held February 1990 ● Bibliography for unknown source ● “Mapping and Sequencing the human genome” by Victor A. McKusick. New England Journal of Medicine April 6, 1989 ● “Mapping and sequencing the human genome: how to proceed” by Lloyd Smith and Leroy Hood. Biotechnology Vol 5, September 1987. ● “New tools, new dilemmas: genetic frontiers” by Kathleen Nolan and Sara Swenson. Hastings Center Report October/November 1988 ● “The limits of genetic inquiry” by Marc Lappé. Hastings Center Report. August 1987. Vol 17. ● “Warning: screening workers for genetic risk” by Thomas H. Murray . Hastings Center Report. February 1983. ● “Special considerations for minority participation in prenatal diagnosis”. Robert F. Murray, Naomi Chamberlain, John Fletcher, Ernest Hopkins, Rudolph Jackson, Patricia A. King, Tabitha M. Powledge. JAMA, March 28, 1980 Vol 243 No. 12 ● Brochure from the Williamsburg Hilton and National Conference Center ● “Mapping the human genome: problems of privacy and free choice” by Ruth Macklin. No source/date ● Letter from Elke Jordan to BCD January 29, 1990. About attending workshop of Ethics Working Group in Williamsburg on February 5-6, 1990. ● “Can aborting ‘imperfect’ children be immoral?” by Adrienne Asch. No date/source ● Copy of a book. Reproductive Laws for the 1990s. Edited by Sherrill Cohen and Nadine Taub. Clifton: Humana Press, 1989.

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Folder 9 - Gore Hrg 11/09/1989 ● Testimony by James D. Watson before the Subcommittee on Science, Technology, and Space Committee on Commerce, Science, and Transportation. United States Senate. November 9, 1989. ● Letter from Mike Nelson to BCD. November 15, 1989. Follow up questions from November 9, 1989 hearing ● Testimony of Maynard Olson. Testimony before the Senate Subcommittees on Science, Technology, and Space. November 9/1989 ● The Human Genome Initiative: A Bioethical View, by Nancy S. Wexler ● Opening statement of Al Gore. “The Human Genome Initiative and the Future of Biotechnology”, November 9, 1989 ● Statement of Robert W. Wood before the Subcommittee on Science, Technology, and Space Committee on Commerce, Science, and Transportation. United States Senate. November 9, 1989. ● Statement of Pete V. Domenici before the Subcommittee on Science, Technology, and Space Committee on Commerce, Science, and Transportation. United States Senate. November 9, 1989. ● Witness list for hearing with handwritten notes ● Transcript of hearing with business card of Irene C. Mangan of the Congressional Clearinghouse on Futures

Outside folder ● Pages 3 and 11 of Marvelous Machines, with notes

Folder 10 - Replies re: genome archive ● Reply from Frank H. Ruddie to BCD. June 1, 1990 ● Reply from Jon Palfreman to BCD. June 4, 1990 ● “The new human genome: mapping inherited diseases” by Eric S. Lander. Princeton Alumni Weekly. No date.

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In a manila envelope sent to BCD. Return address is University of California Department of Chemistry. Postmarked May 30, 1990 ● Letter from Alvin W. Trivelpiece to Mortimer L. Mendelsohn. May 22, 1990. Attached is a post-it note letter to BCD from Ignacio Tinoco. About a major initiative for the Health and Environmental Research Advisory ● Letter from Mortimer L. Mendelsohn to Ignacio Tinoco. September 8, 1986. Information on potential names for new subcommittee ● List of potential members of HERAC Subcommittee on Ordering and Sequencing the Human Genome- with personalized comments ● Letter from Ignacio Tinoco Jr. to Ignacio Tinoco. October 9, 1986. About HERAC ● Letter from Jean M. Hummer to Ignacio Tinoco. October 9, 1986. Confirmation of first meeting of HERAC subcommittee on November 5-6, 1986. ● Letter from Ignacio Tinoco Jr. to Committee Members. March 9, 1987. Draft version of report ● Letter from Ignacio Tinoco Jr. to HERAC members. March 9, 1987. Different version of above? ● Letter from George D. Duda to Ignacio Tinoco. May 21, 1987.Thanking him for work with HERAC subcommittee ● Letter from Ignacio Tinoco Jr to Committee Members. November 10, 1986. Report on first meeting. ● Letter from Robert L. Sinsheimer to Ignacio Tinoco. February 9, 1987. About meeting in Denver and goals. ● Copy of overhead slides. “Phased approach” ● Letter from Charles R. Cantor to Ignacio Tinoco. February 24, 1987. Suggestions for revised report. ● Letter from David A. Smith to Ignacio Tinoco. March 3, 1987. Suggestions for revised report. ● Letter from Dieter Soll to Ignacio Tinoco. January 13, 1987. Thanking him for informing him about subcommittee ● Letter from Leonard Lerman to Ignacio Tinoco. January 19, 1987. Proposal for a National Sequencing Center under the Human Genome Project ● Letter from Gary Stormo to Ignacio Tinoco. His views on defining mapping and sequencing the human genome ● Letter from Leonard S. Lerman to Ignacio Tinoco. December 8, 1986. About meeting of the subcommittee ● Letter from Charles R. Cantor to Ignacio Tinoco Jr. December 12, 1986. Views on genome project ● Notes on Ordering and Sequencing the Human Genome by Dean L. Engelhardt ● Outline of General Principles based on Nov 5-6 1986 Meeting of Subcommittee on Human Genome, by Mort Mendelsohn November 10, 1986 ● Position Paper on Major Issues Facing the DOE Human Genome Program by Charles R. Cantor. With notes ● Letter from Gary Stormo to Ignacio Tinoco. No date. Views on human genome project

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Documents inside a Penn State folder ● In left side flap ○ A copy of “St. Francis Einstein of the Daffodils” (poem) ○ Program for unnamed event April 19, 1990 ○ List of attendees for Spring National Meeting- Society for Health and Human Values 1990 Meeting

● In right side flap ○ “Discovery and Invention: The dynamics of scientific change in medicine” from Spring National Meeting- Society for Health and Human Values April 1990 ○ Document from above meeting- Case study III: Mapping and Sequencing the Human Genome ○ Advertisement for “The Woman in the Body” by Emily Martin ○ Front and back cover of “The Woman in the Body”

Documents inside an unmarked black folder with label “Robert M. Cook-Deegan” ● List of members of Committee on DNA Technology in Forensic Science January 1990 ● Letter from Oskar R. Zaborsky to Robert Cook-Deegan March 27, 1990- to invite BCD to participate in briefing for Committee on DNA Technology in Forensic Science April 17, 1990 ○ Attached is list of participants and agenda and travel plans ● Copy of agenda ● Handwritten note ● List of participants

Folder 3 - NSF Archive Grant ● Summary proposal budget – National Reference Center for Bioethics Literature ● Letter from BCD to Ronald Overmann- proposal for human genome archive ● Proposal from National Reference Center for Bioethics Literature by LeRoy B. Walters 10/1/1989 ● Form- Georgetown University Sponsored Programs Action Notice 2/14/1990 ● Receipt from National Science Foundation Proposal Processing 11/16/1987 ● Memo from Doris Goldstein to Mel Bell with copy of proposal and budget forms November 15, 1989 ○ Attached is a National Reference Center for Bioethics Literature brochure and Scope Note 12 ● Small Grants for Exloratory Research (SGER) Program Announcement- National Science Foundation brochure ● Grants for Research and Education in Science and Engineering- National Science Foundation report ● Letter from Pamela M. Henson to BCD October 16, 1989- information on oral history and videohistory ● Sheet on Smithsonian Videohistory Program average video costs ● Sheet on Smithsonian Videohistory Program videotaping oral history interviews- budgeting ● Smithsonian Institution Archives bibliography on videohistory Cook-Deegan Box 5/7

● Information on video ● Smithsonian Videohistory program set design: videotaped group interviews ● Videotape preservation suggestions ● Information sheet on videocassette tape physical damage ● Brochure from “A Way with Words” transcribing and revision services ● Resume from transciber ● Draft permission forms from Oral History Project Procedures Maunal ● Smithsonian Archives Oral History Project Procedures Manual ● Letter from Doris Goldstein to CD with suggestions for proposal November 10, 1989 ● Letter from CD to Ronald Overmann October 30, 1989- about costs ● Letter from Ronald Overmann to CD October 19, 1989- about evaluation ● NSF proposal outline with handwritten corrections ● Handwritten notes for proposal ● NSF proposal outline with no corrections ● Interview with Charles Cantor August 18, 1988 ● Interview with Michael Hunkapiller August 24, 1988 ● Interview with Harry Noller. No date ● Interview with Walter Gilbert November 11, 1988 ● Interview with Charles Scriver September 19, 1988 ● Interview with Jack Bartley August 18, 1988 ● Interview with Temple Smith November 14, 1988 ● Interview with James Wyngaarden September 19, 1988 ● Letter from Ronald Overmann to BCD- March 2, 1990- request for evaluation ● Center Status Report- Sponsored Programs Summary from 2/01/90 to 7/31/91 ● Copy of above ● Center Status Report- Sponsored Programs detail ● Memo to BCD, Anita Nolen, Bob Veatch, LeRoy Walters from Doris Goldstein- June 13, 1990-about suggestion from Ronald Overmann to host a meeting ○ Attached is Letter from BCD to Doris Goldstein and Bob Veatch June 19, 1990 about meeting of archivists

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Inside Folder 3 is folder from The Institute of Genetics, Religion and Ethics- Two national conferences 1990 and 1992 -Left hand side ● Brochure- A Policy Statement of the National Council of the Churches of Christ in the U.S.A. “Genetic Science for Human Benefit” ● Brochure-Airport Express service for Houston ● Genetics, Religion and Ethics- Two National Conferences- plenary discussions on procedure and methodology during 1990-1991

Packet of documents ● Letter to conference participants to J. Robert Nelson 1/31/1990- information about conference ● Fax to J. Robert Nelson from CD- February 19, 1990-need to rearrange travel plans ● Letter from J. Robert Nelson to CD December 5, 1989- about his participation ● Letter from Jan van Eys, C. Thomas Caskey and J. Robert Nelson to CD- inviting him to participate ● Endorsements of conference ● Letter to J. Robert Nelson from CD- December 10, 1989-needs to participate informally End of packet (still in left hand side) ● Article- “James Watson and the search for biology’s ‘Holy Grail’” by Stephen S. Hall- Smithsonian Magazine Vol 20 February 1990 ● Form for request for 2.0 continuing education units from Institute of Religion

Right hand side ● Group II list of participants ● Schedule of conference March 30-April 1, 1990 ● Participants list ● Selected bibliography for 1990 conference ● Church and Society recommendations and proposals of Central Committee of the World Council of Churches – March 1990 ● Proposed Pronouncement – The Church and Genetic Engineering from Seventeenth General Synod United Church of Christ 1989 ● Ethical Problems of Individuals and Families of Higher Genetic Risk- from General Convention of The Episcopal Church 1985

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Documents not in a folder ● Copy of pages from Science Vol 248 “An animal genome project?” ● Copy of above ● Copy of pages from Science Vol 248 “Learning to drink from a fire hose” ● Copy of above ● Copy of pages from JAMA May 23/30 1990 Vol 263 No 20- “The cystic fibrosis gene: medical and social implications for heterozygote detection” by Benjamin S. Wilfond and Norman Fost ○ Attached to back is a fax sheet showing article was sent to CD ● Copy of page from unknown journal May 18, 1990 “The genetic map is back on track after delays” by Leslie Roberts ● Copy of above ● Letter from Faye Sholiton to CD May 15, 1990- saying pleasure to meet him in Cleveland ● Copy of page from Science Vol 248 “Genome backlash going full force” by Leslie Roberts ● Copy of above ● Letter to Elke Jordan, Mark Guyer, James Watson, Pam Lokken, Leslie Fink and Eric Juengst from CD April 23, 1990- first draft fact sheet on genetic tests and ADA act ● Unclassified telegram from Department of State May 1990 from Embassy in Tokyo to Whitehouse- about biotech-human genome – uncoordinated GOJ efforts may result in private funding ● Unsigned letter to “Nancy” about need to expedite matters ● Advertising from United States Biochemical for sequencing services ● Fax coversheet to CD with attached letters about Jim Watson and Japanese genome groups May 31, 1990 ● Letter from Nachama L. Wilker to CD January 10, 1990- forwarding a copy of position papers of the Council for Responsible Genetics ■ Position papers attached ● Letter from Oskar R. Zaborsky to CD May 3, 1990- thanking him for participation in meeting of Committee on DNA Technology in Forensic Science ● Memo from Bruce Weir to Participants in the April 17, 1990 meeting of the NRC Committee on DNA Technology in Forensic Science- correcting error in overhead transparencies- April 23, 1990 ● Payroll transactions for CD-Sloan –period end 4/30/1990 ● Sponsored Programs Detail-Kennedy Institute of Bioethics- budget information- period end 4/30/1990 ● Sponsored Programs Summary- Sequencing the Human Genome- L. Walters- period end 4/30/1990 ● Non-Payroll Transactions- period end 4/30/1990 ● Sponsored Programs Summary- Human genome Cook-Deegan- period end 4/30/1990 ● Copy of articles from Science Vol 248 ● Unsigned, undated page entitled “Points to Consider” about NCHGR budget Cook-Deegan Box 5/7

● Letter from Eric T. Juengst to Bronwen Loder June 7, 1990 about organizing a workshop ● Backgrounder- NCGHR Bioethics Program Addresses Social and Ethical Implications of Knowledge About Human Genes- June 1990 ● The Cystic Fibrosis Gene: Medical and Social Implications for Heterozygote Detection by Benjamin S. Wilfond and Norman Fost- note that it will be published in JAMA 5/23/90 ● Fax from Robert J. Crawford to CD May 2, 1990 with attached memo for NSF ● Copy of pages from Perspectives in Biology and Medicine Vol 33 No 2 Winter 1990 “Genetics and health care: a paradigm shift” by P.A. Baird ● Memo from Robert Crawford to CD May 17, 1990- about Japanese genome projects ● Fax from Robert Crawford to CD May 2, 1990- copy of 3 above ● Folder and information about Research America sent to CD May 2, 1990 ● List of universities with graduate programs in bioethics dated January 1990 ● Draft entitled “Feasibility studies for large scale DNA sequencing” April 18, 1990 ● Copy of page from news page of Nature Vol 344 1 March 1990 ● List of DOE sequencing technology projects ● A piece of trash (Sony microcassette tape box) ● National Center for Human Genome Research – grants awarded fiscal years 1988- 1990 ● Copy of pages from Genomics 669- “The Italian genome project” by Renato Dulbecco ● Memo to Jerry Miksche to Machi Dilworth March 6, 1990- official written report for trip to Japan- attached is report ● “Sharing Genome Information and By-products” ● Unsigned letter from unknown to Dr. Watson. No date. About clarification regarding the goals of the Human Genome Project ● Roster of NIH-DOE DNA Sequencing Working Group ● Agenda- NIH-DOE DNA Sequencing Working Group May 10. 1990 ● List of DOE sequencing technology projects ● Memo from CD to Elke Jordan April 30, 1990- about archiving matters ● Copy of pages from The Journal of NIH Research April 1990 Vol 2. “The difference in duplicates: twin study highlights brain changes in schizophrenia” by R.L Suddath, G.W. Christison, E.F. Torrey, M.F. Cassanova and D.R. Weinburger ● Human Genome News Vol 2, No 1, May 1990 ● Letter from J. Robert Nelson to CD April 20, 1990 about contributing to next Institute of Religion conferences ● Letter from Charles DeLisis to CD- comments on IUM piece on Human Genome Project ● Report- Public Policy Implications of the Human Genome Project by CD May 1990 ● Testimony of Dr. Eric S. Lander before the Subcommittee on Labor, Health and Human Services, Education and Related Agencies of the House Appropriations Committee April 23, 1990 Cook-Deegan Box 5/7

● Copy of page from The Journal of NIH Research April 1990 Vol 2 “National Center for Human Genome Research” No author. ● Copy of page from the Blue Sheet March 21, 1990. “Human genome 1991 funding request is $25 mil, less than research center sought, Watson tells panel” ● Roster Special Review Committee Meeting for Center Applications July 10-1990 ● Effect of the Human Genome Project on the Funding of Biomedical Research Programs ● Fact Sheet on the Human Genome Project March 6, 1990 ● Letter from Tom Marr to Mark Guyer No date. Attached are letters asking for support for Human Genome Project ● National Center for Human Genome Research Fiscal Year 1989 Grants to Industry ● Copy of pages from Science Vol 248 April 6, 1990. “Orchestrating the Human Genome Project” by Charles R. Cantor ● Copy of pages from Science Vol 248 April 6, 1990. “The Human Genome Project, past, present, future”, James D. Watson ● “The social and political implications of mapping the human genome” by Walter F. Bodmer”. No date. ● Letter from Second Annual Charles L. Lippoldt, M.D. Memorial Symposium in Bioethics to CD- November 20, 1990. Contract for speaking appearances ● Brochure from XIIth Kuhlungsborn Colloquium September 14-19, 1990 ● Above is wrapped in letter from Erhard Geissler to CD March 30, 1990. Thanking him for his help ● Copy of page from Science Vol 248. “Genetic and physical mapping of the human genome” by Jacques S. Beckmann ● The Genome Project, by Norman G. Anderson ● Letter from CD to Elke Jordan and Mark Guyer January 19, 1990. about letter from Clark Elliot regarding archiving- letter is attached ● Roster of Genome Review Group March 27-28, 1990 ● Roster of National Center for Human Genome Research Special Review Committee March 29, 1990 ● Human Genome Quarterly Vol 1 No 3 Winter 1990 ● Copy of pages from Nature Vol 342 2 November 1989- “Bulls, bears and bugs” by (illegible) Davies ● Copy of page from Nature Vol 342 30 November 1989- “Missed opportunity in biology” No author ● Letter to “Dieter and Greg” from “Mark”. No date. Attached is draft of Genome Informatics and the NIH-DOE Joint Informatics Task Force: What is the JITf and What Will it Actually Do?” by Mark L. Pearson ● Letter from Legislative Intern to M/R March 30, 1990- about hearing on biomedical research in the Senate Appropriations Subcommittee on Labor, Health and Human Services, Education and Related Agencies ● Article- “Cost and pace of human genome research could be improved, Watson says” March 21, 1990, Life Sciences ● Copy of pages from Science and Government Report March 1, 1990. Cook-Deegan Box 5/7

● Copy of page from The Blue Sheet February 21, 1990- information about Raub and Harkin underlined ● Faxed article from Nancy to CD- attached is article by Melissa Hendrickson “The Big biology of Leroy Hood” from Johns Hopkins Magazine February 1990 ● Letter from Bettie J. Graham- attached is minutes from NIH-DOE Working Group on Ethical, Legal and Social Issues Related to Mapping and Sequencing the Human Genome- March 12, 1990 Documents inside unmarked blue folder

● Left hand side flap ○ Pile of handwritten notes with calculations and lists ○ Pile of papers with information about mapping the human genome with RFLPs and constructing a 5cM RFLP map and costs involved

● Right hand side flap ○ Appendix VI of “The cost of sequencing the complete human genome” by Christian Burks- with coversheet from Genome Sequencing Workshop March 3-4, 1986 ○ Report on the Human Genome Initiative for the Office of Health and Environmental Research April 1987 ○ Memo from Dave Guston to Costs of Human Genome Project Workshop Participants. August 7, 1987- about estimates from Dr. Charles Cantor on costs of project ○ Article “It’s genetic” by Paul Harvey. August 27-28, 1988 from Los Angeles Times Syndicates ○ Backrounder- NCHGR Bioethics Program Addresses Social and Ethical Implications of Knowledge About Human Genes- June 1990 ○ Letter from Robert L. Sinsheimer to David Peirpont Gardner November 1984- about feasibility of genome project and money from Hoffmans- attached is a position paper ○ Handwritten notes attached to the agenda of Costs of Human Genome Project August 7, 1987, also with notes ○ Biographical Sketches of OTA Staff for the OTA Assessment of Mapping the Human Genome ○ Handwritten table of costs, seems to be some sort of proposal ○ Ethical, Legal and Social Implications (ELSI) Program- National Center for Human Genome Research (NCHGR)- FY activities 1990 as of June 11, 1990 ○ List of names and numbers on sheet entitled New Developments in Biotechnology from the Office of Technology Assessment

Cook-Deegan Box 6/7

Folder 1 - Aki Yoshikawa Japan Contract

Packet 1 ● Draft letter for draft proposals for OTA ● Letter from Gretchen S. Kolsrud to Robert Cook-Deegan about OTA ● List of addresses ● Another copy of draft proposal letter with handwritten note from Barbara to Bob 4/1/82, to-do list and editing marks. List of addresses attached to back ● Akihiro Yoshikawa grant proposal with business card, resume ● Copy of above ● Time table for AY proposal ● Table of costs for AY proposal ● AY resume ● Justification of Source letter ○ Letter to Kent Calder from Gretchen S. Kolsrud – it is same letter saying OTA is accepting proposals March 31, 1987 ○ List of addresses ○ Statement of work ○ Blank summary of costs form ○ Letter from AY to Robert Cook-Deegan with revised costs ○ Copies of AY proposal materials

● Letter from AY to Robert Cook-Deegan beginning of March 1897 explaining credentials and travel plans ● Letter from AY to Robert Cook-Deegan with outline of study and progress report ● “While you were out” message from John Zysman 2/25 ● “While you were out” message from AY 3/9 ● Letter from Alexandra Ferguson to Robert Cook-Deegan June 29, 1987 offering additional funds ● Memo from Gretchen Kolsrud to Robert Cook-Deegan to add travel expenses ● Copy of AY proposal outline ● AY progress report ● Letter from AY to Jacqueline Courteau with final draft and request not to distribute previous drafts ● Letter from AY to Jacqueline Courteau with final expense report ● Letter from Jacqueline Courteau to Gretchen, draft for reviewers ● Statement of Work ● Letter from Jacqueline Courteau to AY September 3, 1987 requesting more editing ● Draft letter for reviewers July 22, 1987 ● Letter from Alexander Ferguson to Robert Cook-Deegan June 29, 1987 about extra funding for AY ● Letter from AY to Robert Cook-Deegan about his work on drafts ○ Draft Cook-Deegan Box 6/7

Packet 2 ● Draft by AY

● Copy of Letter from AY to Robert Cook-Deegan requesting not to distribute previous drafts

Folder 2 ● Empty folder labeled Japan Contract Yoshikawa

Folder 3 - Comments on Japan Contract ● Letter from Chalmers Johnson to Jacqueline Courteau July 28, 1987 – suggestions for AY paper ● Letter from Jack G. Lewis to Jacqueline Courteau August 14, 1987- suggestions for AY paper ● Letter from Robert K. Fujimura to Jacqueline Courteau August 7, 1987 – suggestions for AY paper ● Letter from Robert K. Fujimura to Robert Cook-Deegan December 1, 1987- more suggestions/review of AY paper ● Letter from Laurie Scheffler to Jacqueline Courteau- Ezra Vogel could not review paper July 23, 1987 ● Letter from Martha Lane to Jacqueline Courteau- Kozo Yamamura could not review paper July 27, 1987 ● Letter from Richard J. Samuels August 5, 1987- cannot review paper ● Letter from Elaine Heron to Jacqueline Courteau August 3, 1987- suggestions for AY paper

Folder 4 - International Biotech Background ● Article- “Swedish Pharmacia’s new way of financing biosensor R&D” by Mats Edman, Jan 15, 1987- information on Olympus Payload Integrated ● Article- “Sweden: biotechnology center fully functional in two years” by Ingrid Eriksson February 19, 1987 ● Article- “500 million kroner state support to Danish biotech” by Steffan Dahloff Jan 29, 1987 – On reverse: “FRG-PRC collaboration on MPC75 aircraft” by Barbara Odrich Jan 9, 1987 ● Article- “Status, goals, funding, joint ventures for Austrian biotech” by Peter R. Schlifke March 27, 1987 ● Brief on Austrian Research Advisory Service ● Copy of a page from Nature Vol 330 24/31 December 1987 “Vienna to gain biology center” by Steven Dickman ● Copy of a page from Nature Vol 328 6 August 1987 ● Copy of Nature article Vol 328 27 August 1987- “Formative turbulent months ahead” NA ● Copy of unknown journal- “UK revises rules on gene engineering” by Alison Stewart Cook-Deegan Box 6/7

● Copy of page from New Scientist 28 January 1988- “Britain names chief of new science center” NA ● Copy of page from New Scientist 10 December 1987- “How to stifle innovation” by Max Perutz ● Copy of page from Nature Vol 330 19 November (year illegible)- “Research councils struggling in straitjacket of government rules” by Simon Hadlington ● Copy of page from Biotechnology Vol 6 January 1988- “Phillips, Wadley set venture” by Arthur Klausner ● Article- “Fraunhofer Study examines advanced technology fields” August 20, 1987 ● Article- “European Community role in biotech explained” by Jean-Luc Nothias, May 1987 ● Article- “European biotechnology research, investments profiled” Milan Technologie Elettriche January 1987- on reverse, briefs of EC Bioinformatics Project Funding and New Belgian Genetic Engineering Firm ● Copy of pages from unknown journal. “The impacts of biotechnology” by Edward Yoxen ● Agenda of International Biotechnology Competitive Perspectives and Marketing, April 22, 1987 ● Copy of pages- Trends in Biotechnology 4: Nov 11 November 1986 – “EC- biotechnology: a European challenge” by Robert R. Van Der Meer ● Article- “Technology assessment, R&D evaluation programs spotlighted” Paris R&D Evaluation Newsletter No 87.2, 1987 ● Article- “BMFT reports more private sector initiative in R&D funding” Dusseldorf Handelsblatt July 13, 1987 ● Copy of pages from TIB October 1987 Vol 5 No10 “The greening of biotechnology: the growth of the US biotechnology industry”, by Mark D. Dibner and Nancy G. Bruce ● Copy of Abstracts in Biocommerce Vol 10, No 1 January 11, 1988 ● Copy of Congressional Record-Daily Digest, November 4, 1987 ● Copy of pages from The New Republic- “The Competitiveness Case” by Robert Kuttner ● Copy of page from Washington Post. “Import ban on genetic item asked” by Stuart Auerbach and Malcolm Gladwell 2/17/1988 ● Article- “Northwest a center for biotechnology” by Bill Virgin, 11/28/87 The Morning Times Tribune ● Article- no title. AP 11/24/187 ● Article- no title. AP 11/03/87 ● Agenda for Preliminary Program National Conference on Collaborative Initiatives in Biotechnology November 1-3, 1987 ● Article- “US companies need boost in biotechnology field” by Guy Darst, AP 11/05/1987 ● Article- “Detroit investment company agrees to rescue endotronics”. No author. AP 11/17/87 ● Copy of pages from JPRS-ELS-87-051 “Training in biotechnology said sporadic, inconsistent” by Heti Vilaggazdasag – Hungarian No 37, September 12, 1987 Cook-Deegan Box 6/7

● Copy of pages from JPRS-ELS-87-051 “Academician critical of National Scientific Research Fund” by Magya Tudomany – Hungarian No 7-8, July/August 1987 ● Copy of pages from Nature Vol 330 12 November 1987. “The continuing decline of British science” by Ben R. Martin, John Irvine, Francis Narin and Chris Sterritt

Folder 5 - International Biotech

● Article- “EC research budget impasse breaks, UK compromises” by Philippe Lemaitre- Paris Le Monde July 17, 1987 ● Copy of Abstracts in Biocommerce Vol 9 No 23 December 7, 1987 ● Article- “EC to intensify advisory service to midsize firms” . No author. Technologie Nachrichten-Management Informationen No 457, June 12, 1987 ● Article- “Operational Stage of EC sprint program outlined” No author. Technologie Nachrichten-Management Informationen No 458, June 29, 1987 ● Copy of Abstracts in Biocommerce Vol 9 No 19, October 12, 1987 ● Letter from Blake to “Biotech Fans” May 11, 1987 on Report on Association of Biotechnology Companion meeting on “International Biotechnology: Competitive Perspectives and Marketing” with highlighting

Packet 1 - with binderclip- handwritten label “Biotech: Federal Republic of Germany” ● Copy of article from Nature 328(6128): 305-8 July 23, 1987 reprinted in unknown journal. “West Germany’s unique research grant system” by J. Boeckh ● Article- “Biotechnology funds from BMFT increase annually in 1986-1988” No author. VDI Nachrichten May 29, 1987 ● Article- “FRG’s Riesenhuber assesses national biotechnology R&D” No author. Biotechnologie June 1987 ● Artcle- “FRG commission urges clear guidelines for genetic engineering” by G. Hartmut Altenmueller. VDI Nachrichten January 23, 1987 ● Copy of above ● Article- “FRG scientists consider genetic engineering risks exaggerated” No author. Handelsblatt May 14, 1987 ● Article- “Biotechnology research at Max Planck’s Baur institute” No author. Biotec May 1986 ● Article-“Initial success at new FRG genetic centers described” No author. Technologie Nachrichten-Management Informationen October 28, 1986 ● Article- “FRG’s survey commission rules on genetic engineering” by Reinhard Wandtner. Frankfurter Allgemeine Zeitung February 4, 1987 with highlighting ● Article-“Biotechnology funds from BMFT increase annually in 1986-1988” No author. VDI Nachrichten May 29, 1987 Cook-Deegan Box 6/7

● Article- “FRG’s Riesenhuber assesses national biotechnology R&D” No author. Biotechnologie June 1987 ● Report prepared by Embassy Science and Technology Unit on biotechnology research and development in the FRG- with note from Embassy of the United States of America in Bonn, Germany to Jacqueline Courteau ● Article- “FRG’s Riesenhuber presents DM 7.6 billion 1988 R&D budget” No author. Handelsblatt August 3, 1987 ● Article- “FRG prospects in biotechnology R&D examined” by Norbert Rau. Industrie und Handelskammer November 18, 1986 ● Copy of page of unknown issue of The Scientist. “W. Germany seeks more for science”. No author ● Copy of pages from The Scientist 16 November 1987. “2 Germanys reach out in sci-tech” by Richard Sietmann ● Article- “FRG role in new Eureka projects outlined” No author. Technologie Nachrichten-Management Informationen September 14, 1987 ● Article- “FRG tax reform threatens indirect methods of R&D funding” by G.H. Altenmueller. VDI Nachrichten July 17, 1987 ● Article- “Multiyear study shows FRG industry increasing its R&D financing” No author. Frankfurter Zeitung/Blick Durch Die Wirtschaft July 9, 1987 ● Public Statement on Gene Technology and on the Human Applications of Reproductive and Genetic Engineering (Adopted by the 8th National Assembly of the Green Party in Hagen, FRG February 15-16, 1986) ■ Press briefing ■ Copy of pages from unknown journal “Cabbage- patch larvae set pesticide trend” by Steve Connor ■ Motion for a Resolution in the European Parliament on the deliberate release of genetically engineered organisms in Great Britain ■ Founding appeal of the Gen-Ethisches Netzwerk ■ Business card of Benedikt Harlin ■ Public Statement on Gene Technology and on the Human Applications of Reproductive and Genetic Engineering (Adopted by the 8th National Assembly of the Green Party in Hagen, FRG February 15-16, 1986) ■ Handwritten notes ■ Copy of pages from New Scientist 22 January 1987 “The Greening of Germany” by Fred Pearce

Cook-Deegan Box 6/7

Folder 6 Japan. General Articles, Background. Biotechnology (Japan- Bioethics Background) ● Brochure for MIT-Japan Science and Technology Program ● Microfiche slide for Casement, Robert. The Innovative Japanese. Economist v. 283 June 19, 1982: 5-6, 9-10, 13-14, 16, 21-22, 25-26, 29-30, 32 ● Status of Biotechnology in Japan – 1986 by Arthur Humphry ● Information about The Human Science Promotion Foundation and Japanese biotech companies ● Article- “Directions, applications of S&T discussed” No author. Ekonomisuto 17, 24, 31, March 1987 ● Copy of page from Nature Vol 343 18 January 1990 “Japan’s boom economy invests in science” No author. ● Copy of page from Nature Vol 342 23 November 1989 “Huge profit from drugs” by David Swinbanks ● Copy of page from Nature Vol 343 11 January 1990. “Bigger budgets proposed” by David Swinbanks ● Handwritten note attached to Nominated Member List ● Article- “FRG: GBF firm links with Japan, Braunschweig university” No author. Frankfurter Zeitung/Blick Durch Die Wirtschaft February 5, 1987 ● Article- “Earth frontier science project” No author. Nikkan Kogyo Shimbun March 21, 1987 ● Article- “FRG-Japan biotechnology information Project Bijanca” by Rolf Schmid. Biotechnologie March 3, 1987 ● Copy of pages from Genetic Engineering News January 1988 “U.S. and Japanese biotech alliances increasingly a fact of business life” by Fred Gebhart ● Article- “News update on Miti’s projects” No author. Nihon Shimbun June 1, 1987 ● Draft of “Biotechnology in Japan” by Robert K. Fujimura ● Copy of “Congressional Record Daily Digest” October 15, 1987 ● Copy of article from The Economist June 19, 1982 “Tomorrow’s leaders- A survey of Japanese technology” ● Handwritten notes November 19, 1982 MITI/JETRO ● Questionnaire from Japan External Trade Organization ● Questionnaire for the Japanese Biotechnology Mission ● Copy of pages from unknown source. “Japan struggling with itself” ● Copy of page from unknown source “The U.S. can no longer afford free trade” by William L. Givens ● Handwritten note with address and numbers ● Copy of pages from Forbes Deceber 20, 1982 “Enough of your promises” by Allan Dodds Frank ● Copy of pages from Japan Economic Journal 12/28/1982 “MITI steps up international biotech activity” No author Cook-Deegan Box 6/7

● Letter from Heiichi Hamaoka to Gretchen Kolsrud October 18, 1982 about meeting with Keiichi Aoyagi ● Copy of pages from Financial Times April 1983 “The Winds of Change” by Jurek Martin ● Copy of pages from New Scientist 6 December 1984 “Big is beautiful in biotechnology” by Gene Gregory ● Copy of pages from Science News November 6, 1982 “Nipponese know-how” no author ● Workshop proceedings Japanese Scientific and Technical Information in the United States edited by Reginald B. Gillmor ● Copy of page from Tech Talk March 30, 1983 “Japanese exchange to begin soon” No author ● Document about Protein Engineering Research Institute (PERI) ● Copy of pages from Current Contents November 16, 1987 “Is Japanese science a juggernaut?” No author ● Copy of pages from The Scientist November 30, 1987 “U.S. toughens stance on Japan science pact” by Stephen Greene ● Copy of page from Nature vol 329 22 October 1987 “U.S. pressures Japan over imbalance in basic research” No author ● Copy of page from Nature Vol 329 22 October 1987 “What future now for Japanese biotechnology research?” by David Swinbanks ● Advertisement for Japan Report: Biotechnology ● BRIE working paper “The Japanese Challenge in Biotechnology: Industrial Policy” by Akihiro Yoshikawa ● CRS Report for Congress “Japanese Technical Information: Opportunities to Improve U.S. Access” by Christopher T. Hill October 13, 1987 ● Article- “MAFF research projects reported” No author. Nihon Kogyo Shimbun July 3, 1987 ● Copy of pages from The Scientist Vol 1 No 22 October 5, 1987 “West is urged to seek, use Japanese data” by Robert Kimberley ● Article- “FRG plans database on Japan biotechnology R&D” No author. Technologie Nachrichten-Management Inforationen February 26, 1987 ● Copy of page from Nature Vol 329 17 September 1987 “More money for science to come in Japanese budget” No author. ● Copy of Japan Bioindustry Letters by BIDEC Vol 3 No 8 July 8, 1986 “Biotechnology budgets for ministries & agencies of the Japanese government for 1986” No author. ● Report -Life Science and Biotechnology R&D in Japan (nearly illegible due to bad photocopying) ● Copy of Japan Economic Institute Report February 7, 1986 “Update on Japan’s Biotechnology Industry: Stunted Growth?” No author. ● Report- Notes on Japanese Biotechnology by William K. Cummings 2/16/1987 ● Copy of above Cook-Deegan Box 6/7

● Article- “State of biotech industry in U.S., Japan compared” No author. Tsusan Janaru Febuary 1987 ● Japan’s Road Map- Industry Leaders and Players ● Copy of page from Biotechnology Vol 5 May 1987 “Japanese Biotech: The good with the bad” ● Article in Japanese from Nikkei Biotechnology 1987 2-9 ● Article- “Fusion of biotechnology, electronics discussed” No author. Bio Industry August 1986 ● Article- “Biotechnology-related news update” No author. Nikkei Biotechnology August 11, 1986 ● Report- Japanese Science and Technology: Some recent efforts to improve U.S. monitoring by Nancy R. Miller December 23, 1986 ● Copy of page from unknown journal. “Complex open to Japan, foreign companies: 300 firms to jointly construct research facility in Tsukuba” No author. ● Handwritten note on back of paper listing Japanese Diet Delegation ● Article- “FRG plans database on Japan biotechnology R&D” No author. Technologie Nachrichten-Management Informationen February 26, 1987 ● Copy of page from Nature Vol 329 9 July 1987 “Nature’s new venture in Japan”. No author. ● Preliminary draft of report- The exchange of semiconductor technology between Japan and the United States, by William F. Finan- Presented to the First U.S.-Japan Technological Exchange Symposium October 21, 1981 ● Interim report- Technology and development and international cooperation toward the 21st century by Study Committee on Technology and International Cooperation February 1986 ● Two copies of “Biotechnology Industry” No author. Tsusansho Koho November 22, 1986 ● Article- “STA FY 87 policies, budget outlined” No author. Purometeus Nov-Dec 1986 ● Copy of above ● Handwritten note- phone number for Justin B. Coom

Folder 7 - NBS ● Article- “Accuracy in DNA Technology”, by Keith McKenney, with address and phone number and handwritten note Cook-Deegan Box 7/7

Folder 1 - Chi Tables – raw data from Theresa ● Handwritten tables (Gene or genetic) and (Marker or Linage or Map) and Human

Folder 2 - Figures – Done/ Illustrs extra ● Photograph- Leroy E. Hood left and Jane Sanders with the Caltech sequenator. (Caltech Photo by Robert Paz) ● Photograph- Lloyd Smith works on the Caltech DNA sequenator. (Caltech photo by Robert Paz) Auj no 7 155 ● Photograph – California Institute of Technology DNA sequenator: light from an argon laser aluminates a thin column in which dye-labeled DNA fragments are separated (Caltech Photo) ● Diagram 003A.F23 final ● Diagram 003A. F17 final ● Diagram 003A. F16 final ● Diagram Figure 9-3 ● Diagram 003A. F20 finish ● Diagram 003A. E2B final ● Diagram no lable of chromosome and band size ● Diagram of overlapping genomic clones ● Diagram 003A.F24 final ● Diagram 003A.F22 final ● Diagram 003A.F21 final ● Diagram 003A. E11 final ● Diagram 003.C5 final ● Diagram 003A.C3 final ● Diagram 003A.D6 final ● Diagram 003A.D3B final ● Diagram 003A.F23 ● Packet of photograph ○ Drosophila salivary chromosomes ○ Chrom. Sorting facility 10 min #1 ○ Matching chromosomes/ 01 Brien 4656 ○ Photo of mice “send to Dr. Bob Cook-Deegan 142” on back ● Photo between paper labeled Hood photos ○ DNA sequencing diagram on photo paper

Folder 3 - Chart 1 001-A, B, C “add legend keyed to: Gene or Genetic, Marker or Linkage or Map, and Human” ● Handwritten note from P- to Teresa attached to article Cytogenetic methodologies for gene mapping and comparative analyses in mammalian cell culture systems by Modi, William S.; Nash, William G.; Ferrari, Anna C.; O’Brian, Stephen J. in Gene Analysis Technology 4:75-85, 1987 ● Handwritten notes, list of different people with possible address and field of study? ● Handwritten note- tables for eval. Of ch. 2 digt → geophe. Cook-Deegan Box 7/7

● Handwritten note- Vses of genetic & physical maps ● Handwritten note/diagram – organizational options ● Handwritten note- label crossed out table of different organizations, mission and strengths ● Letter from Susan Sanford (MedSciArtCo) Sept 15, 1987 ● Handwritten note- list of academic press contacts ● Letter from Roger C. Herdman to Theresa Myers discussion contract Sept 30, 1987 ● Diagram- Chart 1 001B ● Diagram- Chart 1 001-C ● Diagram- Chart 1 001-A

Folder 4 - Figures and Tables ● Letter from Susan Sandford (MeSciArtCo) June 26 1987 ● Susan Sandfor business card ● Handwritten note- From Teresa to Jackie discussing Australia figures ● Diagram – Chart 2 002-A ● Diagram- Chart 2-002 B ● Diagram – 003A.D5 Final ● Diagram – 003A.D1, 2V ● Handwritten table, with copies and drafts- table of countries Chart 1 2 parts ● Printout- March 9, 1988 ICU name: nora, Logon ID: JBC, document name: tbworld ● Diagram 0031.D5 final ● Handwritten table (copy) % told that year ● Figure 7-1 caption ● Figure 7-2 caption ● Handwritten note on legend ● Table 7-1 ● Unlisted table Annual Publications in Human Genetics ● Unlisted table Percentage of Total Human Genetics Research Annually ● Table 7-1 ● Unlisted part of table with handwritten notes ● Printout- March 9, 1988 ICU name: nora, Logon ID: JBC, document name: tbworld ● Printout- March 9, 1988 ICU name: nora, Logon ID: JBC, document name: apbiblio ● Appendix E ● Unlisted table Annual Publications in Human Genetics ● Unlisted table Annual Publications in Human Genetics with handwritten notes ● Unlisted table International Research on the Human Genome with handwritten notes ● Unlisted table Percentage of Total Human Genetics Research Annually with handwritten notes ● Handwritten note- to-do list ● Handwritten note – to-do list Cook-Deegan Box 7/7

● Printout- March 9, 1988 ICU name: nora, Logon ID: JBC, document name: apbiblio with to-do list ● Printout- description of CHI with note to Jac ● Handwritten note ● Copy - table of countries Chart 1 2 parts? ● Unlisted table Annual Publications in Human Genetics ● Unlisted table Percentage of Total Human Genetics Research Annually- ● Unlisted table Annual Publications in Human Genetics with handwritten note ● Unlisted table Percentage of Total Human Genetics Research Annually- ● Diagram – Howard Hughes Medical Institute Genome Mapping Resources January 1, 1988 ● Copy of above with: ○ Diagram- signed proofs # citations in world literature: gene mapping #142 ○ Unlisted diagram Human genome mapping (% of Articles) ○ Copy of above ○ Unlisted diagram, title crossed out, no descriptors, handwritten notes ○ Diagram- Human Gene mapping (% of articles) 5B.J ○ Copy of Diagram- signed proofs # citations in world literature: gene mapping #142 2.J ○ Handwritten note from Jacqueline to Teresa 18 November ○ Typed note from BCD to Jackie ○ Diagram- Chart 1 001 C (copy) ○ Diagram – Chart 1 001-A (copy) ○ Diagram- Chart 1 001-B (copy) ○ Diagram- Chart 2 002-A (copy) ● Diagram – Chart 2 002-B ● Appendix E with handwritten notes ● Unlisted Table Annual Publications in Human Genetics (new draft) ● Printout- March 9, 1988 ICU name: nora, Logon ID: JBC, document name: tbworld ● Table 7-1 ● Large packet of handwritten tables, charts, lists of countries

Folder 5 - Illustrations ● Letter from Marilyn Small to Jacqueline Courteau April 15, 1988 -permission to reprint from Scientific American ● Handwritten note from Teresa Myers to S. Cerrovsiae (on back of empty manila envelope) ● Letter from Jacqueline Courteau to Dr. Charles Epstein March 14, 1988 – permission to use material from journal for Mapping Our Genes ● Letter from Jacqueline Courteau to Nick Kelsh April 29, 1988- photos for Mapping Our Genes. The Genome Project: How Big, How Fast? ● Letter from Jacqueline Courteau To Whom it May Concern- March 15, 1988 - permission to use material from Cold Spring Harbor Laboratory publication in Mapping Our Genes Cook-Deegan Box 7/7

● Letter from Jacqueline Courteau to Dr. Charles Epstein March 14, 1988 – permission to use material from journal for Mapping Our Genes ● Response from Cold Spring Harbor Laboratory with permission ● Letter from Jacqueline Courteau To Whom it May Concern March 15, 1988- permission for use from Scientific American for Mapping Our Genes ● Letter from Donald L. Riddle to Jacqueline Courteau March 16, 1988- description of photographs ● Handwritten note from Shirley Tilghman to Jacqueline Courteau with another person’s handwritten notes on back ● FedEx shipping slip showing shipment from Shirley Tilghman to Jacqueline Courteau ● Letter from Nick Kelsh to Jacqueline Courteau ● FedEx shipping slip showing shipment from Nick Kelsh to Jacqueline Courteau ● Handwritten note ● Letter from Valerie S. Lui to Teresa Myers November 19, 1987- photographs ● Article: A DNA probe for the LDL receptor gene is tightly linked to the hypercholesterolemia in a pedigree with early coronary disease, by Leppert, Mark F; Hasstedt, Sandra J.; Holm, Thomas; O’Connell, Peter; Wu, Lily; Ash, Own; Williams, Roger R.; White, Ray in Am J Hum Genet 39: 300-306, 1986 ● Letter from John Postlethwait to Patricia Hoben March 10, 1988- photographs ● Handwritten note from P- to JBC ● Handwritten note from J to Patricia ● Letter from Roger V. Lebo to Jacqueline Courteau- reprints, photographs ● One page of an article- Flow-sorting Analysis of the Human Genome, pg 171 ● Handwritten note from Ruth Foltz ● First page of Flow-sorting analysis of normal and abnormal human genomes by Lebo, R.V.; Anderson, L.A.; Lau, Y.-F.C.; Flandermeyer, R.; Kan, Y.W. journal info illegible date 1986 Cold Spring Harbor Laboratory 087969-052-6/86 ● Handwritten note ● Letter from Larry L. Deaven to Theresa Myers November 25, 1987 with handwritten notes ● Cover of November 1987 issue of Scientific American ● Article: The ancestry of the giant panda by O’Brian, Stephen J. from November 1987 issue of Scientific American ● Permission to print material form from Scientific American ● Letter from Marilyn Small to Jacqueline Courteau April 15, 1988- permission to reprint material from Scientific American ● License fee form from Time Magazine ● Letter from Jacqueline Courteau To Whom it May Concern March 15, 1988- permission to use material from Scientific American ● Letter from Jacqueline Courteau to Shirley Tilghman April 29, 1988- thank you for use of electron micrograph -Mapping Our Genes ● Letter from Jacqueline Courteau to Mark Soloman April 29, 1988- thank you for use of slides -Mapping Our Genes ● Letter from Jacqueline Courteau to Jody Roberts April 29, 1988- thank you for use of karyotypes -Mapping Our Genes Cook-Deegan Box 7/7

● Letter from Jacqueline Courteau to Donald L. Riddle April 29, 1988- thank you for use of photos – Mapping Our Genes ● Letter from Jacqueline Courteau to John Postlethwait April 29, 1988- thank you for use of photos- Mapping our Genes ● Letter from Jacqueline Courteau to Stephen O’Brian April 29, 1988- thank you for use of panda chromosomes- Mapping our Genes ● Letter from Jacqueline Courteau to Roger Lebo April 29, 1988- thank you for figures of chromosomes- Mapping our Genes ● Letter from Jacqueline Courteau to Nick Kelsh April 29, 1988- thank you for use of photos- Mapping Our Genes ● Letter from Jacqueline Courteau to Ruth Foltz April 29, 1988- thank you for use of Southern blot- Mapping Our Genes ● Letter from Jacqueline Courteau to Larry Deaven April 29, 1988- thank you for use of photos- Mapping Our Genes ● Letter from Jacqueline Courteau to The Bettmann Archive April 29, 1988- thank you for use of photos ● Letter from Jacqueline Courteau to Marilyn Small April 29, 1988- thank you for illustration – Mapping Our Genes ● Handwritten notes with addresses, phone numbers and notes for above material

Folder 6 - Bionet/Intelligenetics (Computer networks written on folder) ● IntelliGenetics Jan/Feb 1998 Vol 4, No 1 ● Handwritten note with computer network login information ● Letter from Jacqueline Courteau to Bionet Users for suggestions, no date, with handwritten notes ● Bionet instruction manual ● Letter from Jacqueline Courteau to Sunil Maulik December 4, 1987- about teleconference ● Bionet account information ● Computer Networking and the Formation of a Global Scientific Community, by David Kristofferson ● BIONET: An NIH Computer Resource for Molecular Biology, by Douglas L. Brutlag and David Kristofferson ● Letter from Bionet with information on how to use account ● Letter to “Genomers” about access to Bionet ● Letter from David Kristofferson to Bionet Users about Bionet upgrade ● Information on Sun Microsystems, Inc. ● Copy of IntelliGenetics Jan/Feb 1998 Vol 4, No 1 ● Telenet directory ● Telenet manual ● Copy of page 126 of Science Vol 245 about Bionet shutting down ● Letter from Cyntia Eppard to Bionet Subscribers about shut down

Cook-Deegan Box 7/7

Folder 7 - Bionet ● Copy of page from The Scientist 11/2/1987 “Scientific Discussion Should Go Online” by Sharon Friedman ● Copy of page from Federal Register Vol 52 No 204 October 22, 1987 “Advisory Panel for Advanced Scientific Computing and Networking and Communications Research and Infrastructure; Meeting” ● Copy of page from Nature Vol 330; 3 December 1987 ● Letter from Wendy Janocha about supercomputing training ● Copy of page 126 of Science Vol 245 about Bionet shutting down

Folder 8 - General DB Issues ● Letter from Pamela L. Love (U.S. Department of Agriculture) to Interested Persons. -Pamphlet NBIAP Agriculture Environmental Biotechnology Bulletin Board ● The NLM Technical Bulletin Issue 0146-3055 No 243 July 1989 ● Letter from Wayne Kessler to Government Information Specialist about cost of government reference library ● Order form for 50-State Legislative Directory ● Order form for The California Directories ● Copy of page from unknown journal, contains article “Journal to Ask for Prior Filling of Gene Data” by Louis Weisberg ● Document from Sunil Maulik about Bionet teleconference ● Copy of page from Genetic Engineering News July/August 1987 “Solutions Sought for Coping with Explosion of Reported Sequencing Data” by John S. Makulowich ● Report: EMBL/NIH Workshop Future Databases for Molecular Biology February 25-27, 1987 with highlighting, notes ● Database instructions ● “How Much Sequence Data Will the Data Banks Be Processing in the Near Future?” by Christian Burke submitted to Proceedings of the First CODATA Workshop on Nucleic Acid and Protein Sequencing Data ● “Bio-Informatics in Europe: An Industry Position Paper” submitted by CEFIC (Conseil Europeen des Federations de l’Industrie Chimique) ● Biotechnology Software November/December 1987 ● “Genatlas: a new data base for the human gene map” by M. de Heaulme, M. Le Merrer, J. Frezal ● Addendum to Program, Additional Abstracts, List of Posters and Demonstrations (probably from First CODATA Workshop on Nucleic Acid and Protein Sequencing Data) ● Order form for Protein Sequences and Data Analysis ● Peptide Information Vol 10 No 9 September 25, 1984 ● First CODATA Workshop on Nucleic Acid and Protein Sequencing Data documents ● First CODATA Workshop on Nucleic Acid and Protein Sequencing Data list of attendees ● Montgomery County, MD visitor directory ● GenBank Floppy Diskette users’ guide Appendix A ● First CODATA Workshop on Nucleic Acid and Protein Sequencing Data program and abstracts

Cook-Deegan Box 7/7

Folder 9 - Databases-General/HGML Newsletter/GenBank Newsletter ● GenBank Vol 2 No 3 Summer 1989 ● Continental U.S. Logon table ● Document about library’s access procedure ● HGML Newsletter Vol 1 No 5 October 1988 ● HGML Newsletter January 1989 supplement to August 1988 user guide ● International Logon table ● HGML Newsletter January 1989 Vol 2 No 1 ● Conference brochure- Healing Encounters: Patient-Provider Collaboration Reconsidered, March 27-29, 1989 ● HGML Newsletter Vol 1 No 4 September 1988 ● HGML Newsletter Vol 2 No 3 March 1989 ● HGML Newsletter Vol 2 No 2 February 1989 ● GenBank Vol 2 No 1 January/February 1989 ● HGML Newsletter Vol 2 Nos 4 & 5 April/May 1989 ● HGML User’s Guide August 1988

Outside of folders

● Routing and transmittal slip filled out by Jacqueline Courteau 2/23/88 ● “Problems in Establishing and Maintaining Nucleic Acid and Protein Data-Banks (I) by Jorn Wolters and Volker A. Erdmann ● Computers in Science Vol 1 No 1 Premiere 1987 Table of Contents and “Sequencing the Human Genome: Computers Taking a Leading Role” by Eugene F. Mallove ● Copy of page from Nature Vol 329 September 17, 1987 “Databases” [letter] by Daniel Davison and “Nucleic Acid Database Management” [letter] by David G. George, Lois T. Hunt and Winona C. Barker ● Advertisement for Protein Sequences and Data Analysis ● Advertisement for Computer Applications ● Document on Bionet teleconference ● “Advances in Genomic Analysis” October-November 1987 ● Table 1 Current Descriptors ● Handwritten notes D. Frederickson 8.11.87 ● “Data Explosion: A Challenge for Science and for CODATA” by Alain E. Bussard ● “Problems in Producing a Protein Sequence Data Base” by Yasuhiko Seto and Shumpei Sakakibara ● “Toward Global Data Interfacing” by Daniel R. Masys ● “The Problem with GenBank” by Elvin A. Kabat ● “What is a Database?” by James W. Fickert March 20, 1987 ● “Why are industrial scientists interested in future development of sequence databases?” by Joseph L. Modelevsky with handwritten notes ● “Global Interfacing of People, Places, Data and Knowledge: Calm Seas and Prosperous Voyage?” by Micah I. Krichevsky ● “Why Things Don’t Work When Databases Go Exponential and Other Mysteries of the Late 1980s” by Richard J. Feldman and Richard J. Simpson with handwritten notes Cook-Deegan Box 7/7

● “Semantic and syntactic patterns in the genetic language” by Temple F. Smith with handwritten notes ● “Search for codes in the sequences” by E.N. Trifonov ● “Bionet: An NIH computer resource for molecular biology” by Douglas L. Brutlag and David Kristofferson ● “Expert system simulations as active learning environments” by Douglas L. Brutlag ● “Computer education in biochemistry, chemistry and molecular biology (I)” by Volker A. Erdmann, Udo Klussman, Jorn Wolters and Hans-Ottmar Beckmann ● Patricia Kahn and Lennart Philipson. The European Molecular Biology Laboratory with handwritten notes ● “MERGE: a software package for generating a single Data-Base starting from EMBL and GenBank collections” by M. Attimonelli, C. Lanave, G. Pesole and S. Liuni ● “Statistical quality control of RNA sequence databases” by Dan Jacobs, Estelle Russek- Cohen and David G. Swartz with handwritten notes ● “The MSDN: an international network of microbial and cell line information resources” by M.I. Krichevsky and E. Ross ● “The gene probe/chromosome library database” by D. Maglott ● “GENTAS: a database system for nucleic acid and protein sequence analysis” by Satoru Kuhara, Fumihiro Matsuo, Syouichi Futamura, Toshihisa Takagi, Katsuya Hayashi and Yoshiyuki Sakaki ● “The necessity of iterative approaches in the analysis of sequence data” by Jorn Wolters and Volker A. Erdmann ● “ASDS: a sequence database server” by Deba Patnaik, David G. Swartz and Fred L. Singleton ● Information about InHouse ● “CODATA and protein databanks” by B. Keil with handwritten notes ● “Linking sequence databases to the current scientific literature” by Dennis A. Benson [abstract] ● EMBL/NIH workshop documents with handwritten notes ● Handwritten note ● Advertisement for database documents ● “Building a New Industry” brochure by The Information Industry Association ● Draft of First CODATA Workshop on Nucleic Acid and Protein Sequencing Data program ● Biotechnology Software Vol 4 No 3 May/June 1987 ● First CODATA Workshop on Nucleic Acid and Protein Sequencing Data attendee addresses ● Ordering form for Biotechnology Software ● “What amount of nucleotide sequence data will appear in the near future?” by Christian Burks with handwritten notes ● Copy of page from Nature Vol 327 June 11 1987 ● Business card for Suzanne Mattingly of SRA Technologies, Inc. and handwritten note about her ● Addendum to Program, Additional Abstracts, List of Posters and Demonstrations (probably from First CODATA Workshop on Nucleic Acid and Protein Sequencing Data)