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Division of Research and Sponsored Programs RESEARCH AND SPONSORED PROGRAMS 2018-2019 ANNUAL REPORT DIVISION OF RESEARCH AND SPONSORED PROGRAMS Lily D. McNair, Ph.D. Shaik Jeelani, Ph.D., P.E. Danette Hall, B.S., M.S. Felecia Moss-Grant, B.S., M.S., M.J. President Vice President for Research & Director of Sponsored Programs Associate Director of Compliance Dean of the Graduate School Message from VP, Research & Dean of Graduate School Tuskegee University recognizes the importance of external support of research and sponsored programs and the impact these vital programs have on the development of its students, faculty and society in general. Tuskegee University has a long-standing reputation of being among the nation’s premiere minority research institutions committed to the total development of its students and faculty. In this annual report, it is evident that through our centers of excellence, academic colleges, schools, and other institutional units, our faculty, staff and students are engaged in research that is critical to addressing the global needs of today’s citizens, industries and governments. Since 1996, the Division of Research and Sponsored Programs has more than doubled its annual funding for research and other sponsored programs. The university concluded 2018-2019 with a total annual funding of $37.2 million, which represents an increase of 7.5% over the last year. Credit for this enormous success goes to our faculty members and staff who continue to search for resources and write winning proposals. Staff members in the Division of Research and Sponsored Programs and various departments of the university’s Business and Fiscal Affairs division are also to be commended for their enthusiastic support of the researchers in the grantsmanship process. These grants and contracts not only allow us to fulfill the research mission of Tuskegee University, but also make a huge impact on our academic programs and our students’ educational experience. Tuskegee University’s two Ph.D. programs in Materials Science and Engineering and Integrative Biosciences are prime examples of programs that are offered solely based on the expertise and resources developed by faculty members. Our long-term plan focuses on actively expanding Tuskegee University’s research in the areas of nanobiotechnology, information technology, environmental science and engineering, energy, astronomy, sensors and devices, molecular biology, immunology, public health, toxicology, epidemiology, reproductive and environmental biology, and modeling and simulations. This report highlights only a few major grants received during the July 2018 to July 2019. All grants and contracts received are at the end of this document ii | Tuskegee University Division of Research and Sponsored Programs Annual Report TUSKEGEE UNIVERSITY RESEARCH COUNCIL The Research Council, appointed by the president of the university, functions as the advisory body to the vice president for research and sponsored programs, with the responsibility of recommending policies and procedures to increase the university’s external funding for research and other sponsored programs. The council is also responsible for selecting proposals for submissions to the funding agencies when there is a restriction on the number of proposal that may be submitted. Members: Shaik Jeelani, Chairman Felecia Moss-Grant, Secretary Conrad Bonsi Gwendolyn Gray Research & Graduate School Research & Compliance College of Agriculture, School of Nursing & Allied Health Environment & Nutrition Sciences Danette Hall Naga Korivi Vijay Rangari Aymen Sayegh Office of Sponsored Programs College of Engineering Biosafety Committee Representative College of Veterinary Medicine Joel Wao Fan Wu Clayton Yates Taylor School of Architecture & Construction Science College of Business & Information Science College of Arts & Sciences iii | Tuskegee University Division of Research and Sponsored Programs Annual Report Funds Received Between July 1, 2018 - June 30, 2019 Appalachian Region 0.x% Appalachian Regional Commission DOD DOE 7% 0.x% U.S. Department of Defense (DOD) USDA DOT 27% 0.x% HHS U.S. Department of Education (DOEd) 33% U.S. Department of Transportation (DOT) U.S. Department of Health and Human Services (HHS) Institute of Museum and Library Services National Aeronautics and Space Administration (NASA) National Endowment for the Humanities (NEH) Institute of Museum National Science Foundation (NSF) DOEd and Library Services 16% 0.x% U.S. Department of Education (DOEd) NASA NSF NEH 4% U.S. Department of Agriculture (USDA) 13% 0.x% AWARDS REWARDED BY VARIOUS AGENCIES Dollar Amount Appalachian Regional Commission $25,294.00 Institute of Museum and Library Services $24,022.00 National Aeronautics and Space Administration (NASA) $1,478,827.58 National Endowment for the Humanities (NEH) $99,019.00 National Science Foundation (NSF) $4,621,213.00 U.S. Department of Defense (DOD) $2,392,370.00 U.S. Department of Energy (DOE) $17,380.00 U.S. Department of Agriculture (USDA) $10,120,498.80 U.S. Department of Education (DOEd) $6,037,126.94 U.S. Department of Health and Human Services (HHS) $12,385,490.00 U.S. Department of Transportation (DOT) $29,500.00 TOTAL $37,230,741.32 Tuskegee University Division of Research and Sponsored Programs Annual Report | 1 2018-2019 SIGNIFICANT GRANTS TITLE: Administrative Core, Infrastrature Core, Investigative Core, TITLE: A Precision Medicine Study of How Community Engagement and Project 2 Inflammation May Underlie the Excessive Burden PRINCIPAL INVESTIGATOR: Dr. Clayton Yates of Prostate Cancer in Men of African Ancestry CO-PRINCIPAL INVESTIGATORS: Dr. Temesgen Samuel, PRINCIPAL INVESTIGATOR: Dr. Clayton Yates Dr. Lonnie Hannon, Dr. Stephen Sodeke, Dr. Honghe Wang and Mr. Jason White FUNDING AGENCY: Department of Defense FUNDING AGENCY: National Institute of Health (NIH) (DOD)/United States Army Medical Research Acquisition Activity (USAMRAA) An $8.5 million National Institutes of Health grant is enabling Tuskegee University researchers to improve our understanding of why diseases — such as cancer, obesity and HIV — disproportionately affect mi- Men of African descent experience a dispropor- nority populations, and how targeted community education programs can reduce the pervasiveness of tionately high prostate cancer (PCa) mortality. In these diseases. collaboration with Drs. Stefan Ambs and Michael Cook at the National Cancer Institute (NCI), our Research funded by NIH’s National Institute for Minority Health and Health Disparities (NIMHD) pro- labs have shown that African Americans harbor a distinct immune-inflammation signature, and this is gram will help researchers in the university’s multidisciplinary Center for Biomedical Research examine a risk factor that is associated with aggressive dis- the molecular, genetic and epigenetical determinates that contribute to the ferocity of specific diseases ease. Therefore, our objective is to find genes in Af- among the African-American community. rican Americans that are responsible for this inflam- mation so we can use the right drug to treat these “Through this NIH-funded research, we will gain a better understanding of the health men who suffer from prostate cancer the most. In differences that exist among various races and sub-populations,” said Dr. Clayton this study, we will determine if there is a specific in- Yates, a professor and director of the Center for Biomedical Research. “This in turn flammation-associated gene signature in over 3,000 will enable physicians in the future to have a better understanding of which thera- men of West African ancestry from U.S., Ghana and pies will be more effective among minorities, as well as who the most vulnerable and Nigeria. We will perform next-generation sequenc- underserved segments of our population are.” ing to determine the gene expression profile of these patients and relate it to black men with pros- tate cancer in the U.S. Our study is the first to explore Assisting Yates is Dr. Temesgen Samuel, an associate professor of pathobiology in the relationship between systemic/chronic inflamma- the College of Veterinary Medicine, who is serving as the grant’s program tion, African ancestry, and tumor biology as a cause director. Dr. Honghe Wang, an associate professor of biology in the of disease progression in men of African descent. College of Arts and Sciences whose specialty is in cancer biology, Creating an understanding of how the interaction is contributing to the questions of prevalence and treatment. between chronic inflammation and tumor biology affects PCa progression in a high-risk population One particular disease on which the team is focusing on initially like African-American men offers the opportu- is prostate cancer. Historically, African-American men have had nity to the develop improved prevention and the highest incidences of prostate cancer for any racial and therapeutic strategies using anti-inflammatory ethnic group in the world — more than two-thirds higher than drugs and immune modulators to decrease the prostate cancer disease burden among all white men. African Americans also have the highest mortality men. Out of 48 total applicants, this proposal rates and shortest survival rates of any racial and ethnic group is one of the two is selected for funding by in the U.S. In studying prostate cancer, the team is evaluating the Department of Defense Congressional- the heritable and environmental factors that influence the ris- ly Medical Directed Research Programs for ing rates of the disease among African-American men. During
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