Flight Attendant Medical Research Institute Eleventh Scientific Symposium

FLIGHT ATTENDANT
MEDICAL RESEARCH
INSTITUTE
PUBLICATIONS AND
PRESENTATIONS
2002-2013

Table of Contents

Table of Contents................................................................................................................ 2 2013..................................................................................................................................... 4
Publications 2013............................................................................................................ 4 Presentations and Abstracts 2013 ................................................................................... 8 Book Chapters, etc., 2013............................................................................................. 11
2012................................................................................................................................... 12
Publications 2012.......................................................................................................... 12 Presentations and Abstracts 2012 ................................................................................. 34 Book Chapters, etc., 2012............................................................................................. 45
2011................................................................................................................................... 46
Publications 2011.......................................................................................................... 46 Presentations and Abstracts 2011 ................................................................................. 80 Book Chapters, etc., 2011............................................................................................. 93
2010................................................................................................................................... 94
Publications 2010.......................................................................................................... 94 Presentations and Abstracts 2010 ............................................................................... 128 Book Chapters, etc., 2010........................................................................................... 154
2009................................................................................................................................. 156
Publications 2009........................................................................................................ 156 Presentations and Abstracts 2009 ............................................................................... 192 Book Chapters, etc., 2009........................................................................................... 211
2008................................................................................................................................. 213
2007................................................................................................................................. 254
2006................................................................................................................................. 281
2005................................................................................................................................. 303
2004................................................................................................................................. 323
2003................................................................................................................................. 335
Publications 2003........................................................................................................ 335 Presentations and Abstracts 2003 ............................................................................... 339

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Book Chapters, etc., 2003........................................................................................... 341
2002................................................................................................................................. 342

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FAMRI Publications 2013

2013

Publications 2013

Apelberg BJ, Hepp LM, Avila-Tang E, Gundel L, Hammond SK, , Hovell MF, Hyland A, Klepeis NE, Madsen C, Navas-Acien A, Repace J, Samet JM, Breysse P. Environmental monitoring of secondhand tobacco smoke exposure. Tob Control 2013;22(3):147-155.

Avila-Tang E, Al-Delaimy W, Ashley DL, Benowitz NL, Bernert JT, Kim S, Samet JM, Hecht SS. Assessing secondhand smoke exposure using biological markers. Tob Control 2013 May;(3):164-171.

Avila-Tang E, Elf JL, Cummings KM, Fong GT, Hovell MF, Klein JD, McMillen R, Winickoff JP, Samet JM. Assessing secondhand smoke exposure with reported measures.

Tob Control 2013;22(3):156-163.

Baños-Lara Mdel R, Ghosh A, Guerrero-Plata A. Critical role of MDA5 in the interferon response induced by human metapneumovirus infection in dendritic cells and in vivo. J Virol 2013; 87(2):1242-1251.

Benowitz NL, Dempsey D, Tyndale RF, St Helen G, Jacob P 3rd. Dose-independent kinetics with low level exposure to nicotine and cotinine. Br J Clin Pharmacol 2013;75(1):277-279.

Brait M, Munari E, Lebron C, Noordhuis MG, Begum S, Michailidi C, Gonzalez-Roibon N, Maldonado L, Sen T, Guerrero-Preston R, Cope L, Parrella P, Fazio VM, Ha PK, Netto GJ, Sidransky D, Hoque MO. Genome-wide methylation profiling and the PI3K- AKT pathway analysis associated with smoking in urothelial cell carcinoma. Cell Cycle 2013;12(7).

Carson JL, Brighton LE, Collier AM, Bromberg PA. Correlative ultrastructural investigations of airway epithelium following experimental exposure to defined air pollutants and lifestyle exposure to tobacco smoke. Inhal Toxicol 2013;25(3):134-140.

Crane-Godreau MA, Payne P. A history of secondhand smoke exposure: are we asking the right questions? Front Physiol 2013;4:25.

D'Armiento JM, Goldklang MP, Hardigan AA, Geraghty P, Roth MD, Connett JE, Wise RA, Sciurba FC, Scharf SM, Thankachen J, Islam M, Ghio AJ, Foronjy RF. Increased matrix metalloproteinase (MMPs) levels do not predict disease severity or progression in emphysema. PLoS One 2013;8(2):e56352.

Deng X, Weerapana E, Ulanovskaya O, Sun F, Liang H, Ji Q, Ye Y, Fu Y, Zhou L, Li J, Zhang H, Wang C, Alvarez S, Hicks LM, Lan L, Wu M, Cravatt BF, He C. Proteomewide quantification and characterization of oxidation-sensitive cysteines in pathogenic bacteria. Cell Host Microbe 2013;13(3):358-370.

DiFranza J, Wellman R, Savageau JA, Beccia A, Ursprung WWSA, McMillen R. What

aspect of dependence does the Fagerström Test for Nicotine Dependence Measure? ISRN

Addiction 2013;2013:Article ID 906276, 8 pages Available at

http://www.hindawi.com/isrn/addiction/2013/906276/.

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Dominissini D, Moshitch-Moshkovitz S, Salmon-Divon M, Amariglio N, Rechavi G. Transcriptome-wide mapping of N6-methyladenosine by m6A-seq based on immunocapturing and massively parallel sequencing. Nat Protoc 2013;8(1):176-189.

Eppert BL, Wortham BW, Flury JL, Borchers MT. Functional characterization of T cell populations in a mouse model of chronic obstructive pulmonary disease. J Immunol 2013;190(3):1331-1340.

Gally F, Chu HW, Bowler RP. Cigarette smoke decreases airway epithelial FABP5

expression and promotes Pseudomonas aeruginosa infection. PLoS One

2013;8(1):e51784. García-Esquinas E, Loeffler LF, Weaver VM, Fadrowski JJ, Navas-Acien A. Kidney function and tobacco smoke exposure in US adolescents. Pediatrics [Epub 2013 Apr 8].

Geraghty P, Hardigan AA, Wallace AM, Mirochnitchenko O, Thankachen J, Arellanos L, Thompson V, D'Armiento JM, Foronjy RF. The GPx1-PTP1B-PP2A axis: a key determinant of airway inflammation and alveolar destruction. Am J Respir Cell Mol Biol [Epub 2013 Apr 5].

Goldklang MP, Marks SM, D’Armiento JM. Second hand smoke and COPD: lessons from animal studies. Front Physiol 2013;4:30.

Goldstein I, Rivlin N, Shoshana OY, Ezra O, Madar S, Goldfinger N, Rotter V. Chemotherapeutic agents induce the expression and activity of their clearing enzyme CYP3A4 by activating p53. Carcinogenesis 2013;34(1):190-198.

Guan Y, Torres RM, Hartney JM. The influence of Arhgef1 on pulmonary leukocyte function. Immunol Res 2013;55(1-3):162-166.

Henschke CI, Yip R, Yankelevitz DF, Smith JP; International Early Lung Cancer Action Program Investigators. Definition of a positive test result in computed tomography screening for lung cancer: a cohort study. Ann Intern Med 2013;158(4):246-252.

Izhar L, Ziv O, Cohen IS, Geacintov NE, Livneh Z. Genomic assay reveals tolerance of DNA damage by both translesion DNA synthesis and homology-dependent repair in mammalian cells. Proc Natl Acad Sci U S A. 2013;110(16):E1462-1469.

Jabaut J, Ather JL, Taracanova A, Poynter ME, Ckless K. Mitochondrial dysfunction enhances IL-1β secretion independent of Nlrp3 S-glutathionylation. In press, Free

Radical Biology and Medicine 2013[Epub Jan 21].

Jones IA, St Helen G, Meyers MJ, Dempsey DA, Havel C, Jacob P 3rd, Northcross A, Hammond SK, Benowitz NL. Biomarkers of secondhand smoke exposure in automobiles. Tob Control 2013;01-07.

Jordaan G, Liao W, Sharma S. E-cadherin gene re-expression in chronic lymphocytic leukemia cells by HDAC inhibitors. BMC Cancer 2013;13(1):88.

Kang TB, Yang SH, Toth B, Kovalenko A, Wallach D. Caspase-8 blocks kinase RIPK3- mediated activation of the NLRP3 inflammasome. Immunity 2013;38(1):27-40.

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Kenche H, Baty CJ, Vedagiri K, Shapiro SD, Blumental-Perry A. Cigarette smoking affects oxidative protein folding in endoplasmic reticulum by modifying protein disulfide isomerase. FASEB J 2013;27(3):965-977.

Kim BS, Serebreni L, Hamdan O, Wang L, Parniani A, Sussan T, Stephens RS, Boyer L, Damarla M, Hassoun PM, Damico RL. Xanthine oxidoreductase is a critical mediator of cigarette smoke-induced endothelial cell DNA damage and apoptosis. Free Radic Biol Med [Epub 2013 Feb. 4].

Kratzer A, Salys J, Nold-Petry C, Cool C, Zamora M, Bowler R, Koczulla AR, Janciauskiene S, Edwards M, Dinarello CA, Taraseviciene-Stewart L. Role of IL-18 in second hand smoke-induced emphysema. Am J Respir Cell Mol Biol [Epub 2013 Feb 7].

Kulkarni R, Randis TM, Antala S, Wang A, Amaral FA, Ratner AJ βH/C of group B streptococci enhances host inflammation but is dispensable for establishment of urinary tract infection. PLoS One 2013; 8(3): e59091.

Laden F, Chiu YH, Garshick E, Hammond SK, Hart JE. A cross-sectional study of secondhand smoke exposure and respiratory symptoms in non-current smokers in the U.S. trucking industry: SHS exposure and respiratory symptoms. BMC Public Health. 2013;13(1):93.

Levy DE, Rigotti NA, Winickoff JP. Tobacco smoke exposure in a sample of Boston public housing residents. Am J Prev Med 2013;44(1):63-66.

Li H, Wood J, Whitten K, Vadival S, Seng S, Makriyannis A, Avraham S, Avraham H. Inhibition of fatty acid amide hydrolase activates Nrf2 signaling and induces heme oxygenase 1 transcription in breast cancer cells. Br J Pharmacol [Epub 2013 Jan].

Licht AS, Hyland A, Travers MJ, Chapman, S. Secondhand smoke exposure levels in outdoor hospitality venues: a qualitative and quantitative review of the research literature.

Tob Control 2013;22(3):172-179.

Liu Y, Antwi-Boampong S, Belbruno JJ, Crane-Godreau M, Tanski S. Detection of secondhand cigarette smoke via nicotine using conductive polymer films. Nicotine Tob Res [Epub 2013 Mar 11].

Madar S, Harel E, Goldstein I, Stein Y, Kogan-Sakin I, Kamer I, Solomon H, Dekel E, Tal P, Goldfinger N, Friedlander G, Rotter V. Mutant p53 attenuates the anti-tumorigenic activity of fibroblasts-secreted interferon beta. PLoS One 2013;8(4):e61353.

Mannam P, Zhang X, Shan P, Zhang Y, Shinn AS, Zhang Y, Lee PJ. Endothelial MKK3 is a critical mediator of lethal murine endotoxemia and acute lung injury. J Immunol 2013;190(3):1264-1275.

Martin RA, Ather JL, Lundblad LKA, Suratt, BT, Boyson JE, Budd RC, Alcorn JF, Flavell RA, Eisenbarth SC., Poynter ME. Interleukin-1 receptor and caspase-1 are required for the Th17 response in NO₂-promoted allergic airway disease. Am J Resp Cell & Mol Biol 2013 [Epub Jan 7].

Messier EM, Day BJ, Bahmed K, Kleeberger SR, Tuder RM, Bowler RP, Chu HW, Mason RJ, Kosmider B. NAC protects murine alveolar type II cells from cigarette smoke injury in an Nrf2-independent manner. Am J Respir Cell Mol Biol [Epub 2013 Mar 14].

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Molchadsky A, Ezra O, Amendola PG, Krantz D, Kogan-Sakin I, Buganim Y, Rivlin N, Goldfinger N, Folgiero V, Falcioni R, Sarig R, Rotter V. p53 is required for brown adipogenic differentiation and has a protective role against diet-induced obesity. Cell

Death Differ 2013;20(5):774-783.

Peters EB, Christoforou N, Leong KW, Truskey GA. Comparison of mixed and lamellar coculture spatial arrangements for tissue engineering capillary networks in vitro. Tissue Eng Part A 2013;19(5-6):697-706.

Solomon O, Oren S, Safran M, Deshet-Unger N, Akiva P, Jacob-Hirsch J, Cesarkas K, Kabesa R, Amariglio N, Unger R, Rechavi G, Eyal E. Global regulation of alternative splicing by adenosine deaminase acting on RNA (ADAR). RNA 2013;19(5):591-604.

Tumati V, Kumar S, Yu L, Chen B, Choy H and Saha D. Effect of PF-02341066 (Crizotinib) and radiation in non small cell lung cancer cells. Oncol Rep 2013;29(3):1094-1100.

Turino GM, Ma S, Lin YY, Cantor JO, Luisetti M. Matrix elastin: A promising

biomarker for COPD. Am J Respir Crit Care Med 2011;184:637-641.

Vigodner M, Shrivastava V, Gutstein LE, Schneider J, Nieves E, Goldstein M, Feliciano M, Callaway M. Localization and identification of sumoylated proteins in human sperm: excessive sumoylation is a marker of defective spermatozoa. Hum Reprod 2013;28(1):210-223.

Weingarten-Gabbay S, Khan D, Liberman N, Yoffe Y, Bialik S, Das S, Oren M, Kimchi A. The translation initiation factor DAP5 promotes IRES-driven translation of p53 mRNA. Oncogene [Epub 2013 Jan 14].

Wilson AA, Kwok LW, Porter EL, Payne JG, McElroy GS, Ohle SJ, Greenhill SG, Blahna MT, Yamamoto K, Jean JC, Mizgerd J, and Kotton DN. Lentiviral delivery of RNAi for in vivo lineage specific modulation of gene expression in mouse lung macrophages. Mol Ther [Epub 2013 Feb 12].

Wilson, KM, Pier JC, Wesgate SC, Cohen J, Blumkin AK. Secondhand tobacco smoke exposure and severity of influenza in hospitalized children. JPediatr 2013;162(1):16-21.

Winickoff J, McMillen R, Klein JD. The Joint Commission’s new tobacco-cessation measures. Letter in response to: The opportunity for tobacco-cessation when a patient is hospitalized – going beyond the measures. N Engl J Med 2012;366(25):2429.

Wu Q, Case SR, Minor MN, Jiang D, Martin RJ, Bowler RP, Wang J, Hartney JM, Karimpour-Fard A, Chu HW. A novel function of MUC18: Amplification of lung inflammation during bacterial infection. Am J Pathol 2013;182(3):819-827.

Yankelevitz DF, Henschke CI, Yip R, Boffetta P, Shemesh J, Cham MD, Narula J, Hecht HS. Secondhand tobacco smoke in never smokers is a significant risk factor for coronary artery calcification. JACC Cardiovasc Imaging [Epub 2013 March 8].

Ye M, Zhang H, Amabile G, Yang H, Staber PB, Zhang P, Levantini E, Alberich-Jordà M, Zhang J, Kawasaki A, Tenen DG. C/EBPa controls acquisition and maintenance of adult hematopoietic stem cell quiescence. Nat Cell Biol [Epub 2013 Mar 17].

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FAMRI Presentations and Abstracts 2013

Presentations and Abstracts 2013

Aravamudan B, Thompson MA, Pabelick CM, Prakash YS. Signaling mechanisms involved in cigarette smoke-induced alterations in airway smooth muscle mitochondrial morphology and dynamics. Presented at the American Thoracic Society International Conference. Philadelphia, PA, May 17-22, 2013.

Bhandary YP, Shetty SK, Marudamuthu AS, Ji H, Fu J, Idell S, Boggaram, VB, Neuenschwander PF, Morris GB and Shetty S. Regulation of alveolar epithelial injury and lung remodeling by p53-mediated changes in urokinase and plasminogen activator inhibitor-1 [abstract]. American Thoracic Society International Conference International Conference. Philadelphia, PA, May 17-22, 2013.

Brown KC, Lau JK, Thornhill BA, Crabtree CM, Dom AM, Witte TR, Hardman WE, McNees CA, Stover CM, Carpenter AB, Luo H, Chen YC, Shiflett BA, Dasgupta P. Inhibition of cholinergic signaling causes apoptosis in human bronchioalveolar carcinoma. Presented at the Experimental Biology Conference. Boston, MA, Apr. 20, 2013.

Dasgupta P, Lau JK, Brown KC, Luo H, Chen YC. Nicotine increases the expression of alpha7-nicotinic receptors (alpha7-nAChRs) in human squamous cell lung cancer cells via Sp1/GATA pathway. Presented at the Experimental Biology Conference. Boston, MA Apr 20, 2013.

Degar,A; Kenche,H; Pandit,K.; Kaminski,N; Richards,D; Nelson,C and BlumentalPerry,A. miRNA-805 up-regulation in response to cigarette smoke challenge regulates alveolar type ii cells regeneration and repair capacity. Presented at the American Thoracic Society meeting. Philadelphia, PA, May 17-22, 2013. for COPD.

DiFranza JR, McMillen R, Wellman RJ. Black and Hispanic smokers are less likely than whites to be tobacco dependent. Presented at the Society for Research on Nicotine and Tobacco 19^thAnnual International Meeting, Boston MA, Mar 13-16, 2013.

Drehmer JE, Nabi-Burza E, Ossip D, Rigotti NA, Woo H, Chang Y, Winickoff JP. How thirdhand smoke beliefs of parents are associated with smoking attitudes and behaviors. Presented at the 2013 Pediatric Academic Societies Annual Meeting. Washington DC, May 4-7, 2013.

Groner J, Huang H, Eastman N, Lewis LM, Kuck J, Schanbacher BL, Hoffman R, Bauer JA. Oxidative stress in youth and adolescents exposed to secondhand smoke. Presented at the 2013 Pediatric Academic Societies Annual Meeting. Washington, DC, May 4-7, 2013.

Kim BS, Serebreni L, Hamdan O, Boyer L, P.M. Hassoun PM, Damico RL. Xanthine oxidoreductase is a critical mediator of cigarette smoke-induced endothelial cell DNA damage. Presented at the American Thoracic Society International Conference, Philadelphia, PA, May 17-22, 2013.

Levantini E,* Basseres DS, Zhang WC, Welner RS, Alberich-Jorda M, Yong KJ, Thakkar BM, Zhang J, Battelli C, Hetherington CJ, Ye M, O’Brien K, Magli MC, Loh M, Nga ME, Pang YH, Borczuk AC, Varticovski L, Kocher O, Zhang P, Soo RA, Lim B,

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FAMRI Presentations and Abstracts 2013

Halmos B, Tenen DG*. C/EBPα acts as tumor suppressor in lung cancer by inhibiting the proto-oncogene Bmi-1. Presented at the Proceedings of the American Association for Cancer Research Annual Meeting, Washington, DC, Apr. 6-10, 2013.

Lopez J, Chupp GL, Gomez JL. Meta-analysis of the published asthma transcriptome identifies a protocadherin-gamma cluster. Presented at the American Thoracic Society Meeting, Philadelphia, PA, May 17-22, 2013.

Lu J, Zhang Y, Nguyen P, Fedulov A, Cernadas M, Kobzik L, Haley KJ. Maternal smoking causes postnatal T regulatory cell abnormalities. Presented at the American Thoracic Society Meeting, Philadelphia, PA, May 17-22, 2013.

Mahabee-Gittens E, Collins BN, Murphy SA, Woo H, Chang Y, Dempsey J, Weiley V, Winickoff JP. The parent-child dyad and parents who quit smoking successfully. Presented at the Pediatric Academic Societies Annual Meeting. Washington DC, May 4- 7, 2013.

McClelland E, Colvin L, Valentine N, McMillen R. Trends in poly-tobacco use among Mississippi secondary students. Presented at the 59th Annual Meeting of the Southeastern Psychological Association. Atlanta, GA, Mar 13-16, 2013.

Nabi-Burza E, Wasserman R, Chang Y, Finch S, Ossip D, Woo H, Winickoff JP. Do parents who smoke quit spontaneously? Presented at the Pediatric Academic Societies Annual Meeting. Washington, DC, May 4-7, 2013.

Ossip DJ, Woo H, Chang Y, Nabi-Burza E, Rigotti N, Winickoff JP. Do parents who smoke want their child’s pediatrician to address their smoking – and does it occur? Presented at the SRNT 19^thAnnual International Meeting. Boston MA, Mar 13-16, 2013.

Sathish V, Thompson MA, Freeman M, Jerde C, Pabelick CM, Prakash YS. Cigarette smoke exposure interferes with estrogen-induced NO production in human bronchial epithelial cells. Presented at the American Thoracic Society International Conference. Philadelphia, PA, May 17-22, 2013.