University of Nebraska Medical Center DigitalCommons@UNMC MD Theses Special Collections 5-1-1939 Agranulocytic angina Louis T. Davies University of Nebraska Medical Center This manuscript is historical in nature and may not reflect current medical research and practice. Search PubMed for current research. Follow this and additional works at: https://digitalcommons.unmc.edu/mdtheses Part of the Medical Education Commons Recommended Citation Davies, Louis T., "Agranulocytic angina" (1939). MD Theses. 737. https://digitalcommons.unmc.edu/mdtheses/737 This Thesis is brought to you for free and open access by the Special Collections at DigitalCommons@UNMC. It has been accepted for inclusion in MD Theses by an authorized administrator of DigitalCommons@UNMC. For more information, please contact
[email protected]. AGRANULOCYTIC ANGINA by LOUIS T. DAVIES Presented to the College of Medicine, University of Nebraska, Omaha, 1939 TABLE OF CONTENTS Introduction • . 1 Definition •• . • • 2 History . 3 Etiology ••• . • • 7 Classification .• 16 Symptoms and Course • . • • • 20 Experimental Work • • •• 40 Pathological Anatomy • • • . 43 Diagnosis and Differential Diagnosis •• . • 54 Therapy Prognosis • • • • • . 55 Discussion and Summary • • • • • • • 67 Conclusions • • • • • • • • • • • • • 73 ·Bibliography • • • • • • • • • • 75 * * * * * * 481028 _,,,....... ·- INTRODUCTION Agranulocytic Angina for the past seventeen years has been highly discussed both in medical centers and in literature. During this time the understanding of the disease has developed in the curriculum of the medical profession. Since 1922, when first described as a clinical entity by Schultz, it has been reported more frequently as the years passed until at the present time agranulocytosis is recognized widely as a disease process. Just as with the development of any medical problem this has been laden with various opinions on its course, etiology, etc., all of which has served to confuse the searching medical mind as to its true standing.