UvA-DARE (Digital Academic Repository)

The KLF2 in vascular biology

Boon, R.A.

Publication date 2008

Link to publication

Citation for published version (APA): Boon, R. A. (2008). The transcription factor KLF2 in vascular biology.

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Download date:28 Sep 2021 Supplementary data: repressed by KLF2 Dekker et al.

LocusLink Accession Sequence Description Fold p-value ID number symbol change (FDR)

6347 NM_002982 CCL2 chemokine (C-C motif) ligand 2 (CCL2) . -15.41 6.7E-42

7123 NM_003278 TNA tetranectin (plasminogen binding ) (TNA) . -8.34 2.5E-13

1282 NM_001845 COL4A1 collagen, type IV, alpha 1 (COL4A1) . -7.83 6.7E-42

7057 NM_003246 THBS1 thrombospondin 1 (THBS1) . -7.81 6.7E-42

5054 M16006 SERPINE1 plasminogen activator inhibitor-1 (PAI-1) mRNA, complete cds. . -7.38 6.7E-42

7368 AL137342 UGT8 mRNA; cDNA DKFZp761G1111 (from clone DKFZp761G1111). . -6.68 2.2E-08

1906 NM_001955 EDN1 endothelin 1 (EDN1) . -5.33 1.3E-37

64399 AY009951 HHIP hedgehog-interacting protein mRNA, complete cds. . -4.70 3.2E-34

22918 NM_012072 C1QR1 complement component 1, q subcomponent, 1 (C1QR1) . -4.37 3.5E-24

1848 NM_001946 DUSP6 dual specificity phosphatase 6 (DUSP6), transcript variant 1 . -4.25 6.7E-42

131583 AF147314 FAM43A full length insert cDNA clone YA84H07. . -4.04 5.8E-11

7980 NM_006528 TFPI2 tissue factor pathway inhibitor 2 (TFPI2) . -3.96 4.1E-03

285580 AF131822 FLJ90723 clone 24905 mRNA sequence. . -3.75 1.5E-40

367 L29496 AR mRNA, complete cds. . -3.68 5.7E-03

AL117595 mRNA; cDNA DKFZp564C2063 (from clone DKFZp564C2063). . -3.59 2.5E-41

23768 NM_013231 FLRT2 fibronectin leucine rich transmembrane protein 2 (FLRT2) . -3.57 9.2E-24

81567 AK025006 TXNDC5 cDNA: FLJ21353 fis, clone COL02771. . -3.53 4.3E-14

2791 NM_004126 GNG11 guanine nucleotide binding protein (G protein), gamma 11 (GNG11) . -3.39 6.7E-42

2171 NM_001444 FABP5 fatty acid binding protein 5 (psoriasis-associated) (FABP5) . -3.37 3.2E-29

9976 NM_005127 CLECSF2 C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 2 (activation-induced) (CLE. -3.20 2.8E-07

5898 NM_005402 RALA v-ral simian leukemia viral oncogene homolog A (ras related) (RALA) . -3.14 1.4E-35

3399 D28449 ID3 mRNA for helix-loop-helix protein 1R21, 5'UTR (sequence from the 5'cap to the start codon). . -3.06 2.5E-20

388 D16875 RHOB HepG2 3' region cDNA, clone hmd1f06. . -3.03 1.2E-27

10409 NM_006317 BASP1 brain abundant, membrane attached signal protein 1 (BASP1) . -3.02 1.3E-07

5881 NM_005052 RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) (RAC3) . -2.96 7.4E-11

79705 AK026772 LRRK1 cDNA: FLJ23119 fis, clone LNG07978. . -2.95 7.7E-15

1636 S81361 ACE angiotensin I-converting enzyme [, gastric HGT-1 cell line, mRNA Partial, 405 nt]. . -2.95 2.2E-27

2798 NM_000406 GNRHR gonadotropin-releasing (GNRHR) . -2.91 2.2E-14

57509 AB033114 MTUS1 mRNA for KIAA1288 protein, partial cds. . -2.90 2.4E-24

3576 M17017 IL8 beta-thromboglobulin-like protein mRNA, complete cds. . -2.90 1.4E-10

51705 NM_016242 EMCN endomucin (EMCN) . -2.84 1.3E-08

1490 NM_001901 CTGF connective tissue growth factor (CTGF) . -2.83 2.9E-21

7289 NM_003324 TULP3 tubby like protein 3 (TULP3) . -2.82 6.2E-13

NM_014102 . -2.81 2.5E-11

27122 NM_013253 DKK3 dickkopf homolog 3 (Xenopus laevis) (DKK3) . -2.79 1.8E-09

29798 NM_013310 C2orf27 hypothetical protein AF038169 (AF038169) . -2.79 6.7E-42

9454 NM_004838 HOMER3 homer homolog 3 (Drosophila) (HOMER3) . -2.79 2.1E-20

5157 NM_006207 PDGFRL platelet-derived growth factor receptor-like (PDGFRL) . -2.78 2.7E-09

Page 1 / 11 Supplementary data: Genes repressed by KLF2 Dekker et al.

161198 AF161403 C14orf27 HSPC285 mRNA, partial cds. . -2.74 1.9E-27

AF147305 full length insert cDNA clone YA80A03. . -2.72 1.4E-11

10587 NM_006440 TXNRD2 thioredoxin reductase 2 (TXNRD2), nuclear gene encoding mitochondrial protein, transcript variant 1 . -2.72 1.8E-12

27 AK025877 ABL2 cDNA: FLJ22224 fis, clone HRC01703. . -2.71 9.0E-14

652 NM_001202 BMP4 bone morphogenetic protein 4 (BMP4), transcript variant 1 . -2.69 1.9E-12

64943 AF131781 FLJ12442 clone 24901 mRNA sequence, complete cds. . -2.66 1.7E-24

23308 AF289028 ICOSLG transmembrane protein B7-H2 ICOS ligand mRNA, complete cds. . -2.66 6.0E-16

4070 NM_002353 TACSTD2 tumor-associated calcium signal transducer 2 (TACSTD2) . -2.65 5.1E-14

131566 AK001362 DCBLD2 cDNA FLJ10500 fis, clone NT2RP2000369. . -2.64 4.5E-12

83641 AK024648 C10orf45 cDNA: FLJ20995 fis, clone CAE02480. . -2.63 1.9E-03

3791 AF035121 KDR KDR/flk-1 protein mRNA, complete cds. . -2.61 3.1E-12

162998 X64975 OR7D2 H.sapiens mRNA HTPCRH03 for olfactory receptor. . -2.59 2.4E-32

55041 NM_017958 PLEKHB2 pleckstrin domain containing, family B (evectins) member 2 (PLEKHB2) . -2.55 4.0E-09

1303 AL359627 COL12A1 mRNA; cDNA DKFZp586K2324 (from clone DKFZp586K2324). . -2.54 9.7E-07

6594 NM_003069 SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 (SMARCA1), tra . -2.53 3.6E-09

23370 AB011093 ARHGEF18 mRNA for KIAA0521 protein, partial cds. . -2.52 1.4E-22

5569 NM_006823 PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha (PKIA), transcript variant 1 . -2.49 3.0E-16

29970 NM_014575 SCHIP1 schwannomin interacting protein 1 (SCHIP1) . -2.48 3.7E-08

25937 AL050107 WWTR1 mRNA; cDNA DKFZp586I1419 (from clone DKFZp586I1419); partial cds. . -2.47 1.8E-12

51256 NM_016495 TBC1D7 TBC1 domain family, member 7 (TBC1D7) . -2.46 7.5E-26

2250 NM_004464 FGF5 growth factor 5 (FGF5), transcript variant 1 . -2.46 4.2E-05

59277 AF278532 NTN4 beta-netrin mRNA, complete cds. . -2.46 7.5E-13

8614 NM_003714 STC2 stanniocalcin 2 (STC2) . -2.45 3.9E-03

8862 NM_017413 APLN apelin (APLN) . -2.45 3.2E-03

5998 U27655 RGS3 RGP3 mRNA, complete cds. . -2.44 2.8E-09

29057 NM_014138 TMEM29 PRO0659 protein (PRO0659) . -2.42 1.1E-12

AF100640 MB2 metastasis related protein (MB2) mRNA, partial cds. . -2.42 1.8E-16

2167 NM_001442 FABP4 fatty acid binding protein 4, (FABP4) . -2.41 2.3E-06

143686 AF086251 SESN3 full length insert cDNA clone ZD40A05. . -2.41 5.5E-08

27344 NM_013271 PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor (PCSK1N) . -2.38 3.1E-20

359845 AF085987 MGC45871 full length insert cDNA clone YU05C01. . -2.38 1.3E-07

1118 NM_003465 CHIT1 chitinase 1 (chitotriosidase) (CHIT1) . -2.38 2.1E-07

170692 AF086229 ADAMTS18 full length insert cDNA clone ZD16H11. . -2.34 1.2E-05

6925 AK021980 TCF4 cDNA FLJ11918 fis, clone HEMBB1000272. . -2.34 5.0E-11

55172 NM_018139 C14orf104 14 open reading frame 104 (C14orf104) . -2.34 6.9E-04

6869 NM_001058 TACR1 tachykinin receptor 1 (TACR1), transcript variant long . -2.33 3.1E-09

26659 NM_017506 OR7A5 olfactory receptor, family 7, subfamily C, member 1 (OR7C1) . -2.31 2.5E-09

79709 AK025982 GLT25D1 cDNA: FLJ22329 fis, clone HRC05659. . -2.31 9.0E-08

3763 NM_002240 KCNJ6 potassium inwardly-rectifying channel, subfamily J, member 6 (KCNJ6) . -2.31 7.9E-07

10367 AL117423 CBARA1 mRNA; cDNA DKFZp564C246 (from clone DKFZp564C246); complete cds. . -2.30 3.3E-30

AK023061 cDNA FLJ12999 fis, clone NT2RP3000324. . -2.29 2.1E-03 Page 2 / 11 Supplementary data: Genes repressed by KLF2 Dekker et al.

9518 NM_004864 GDF15 prostate differentiation factor (PLAB) . -2.27 4.6E-12

AK023522 cDNA FLJ13460 fis, clone PLACE1003373. . -2.27 2.8E-09

5108 AJ297349 PCM1 t(8;10)(p21.3;q11.2) translocation breakpoint for partial RET/PCM-1 fusion gene. . -2.27 2.4E-10

7020 NM_003220 TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) (TFAP2A) . -2.27 7.5E-03

4904 NM_004559 NSEP1 nuclease sensitive element binding protein 1 (NSEP1) . -2.26 8.1E-12

7564 AF244088 ZNF16 finger protein mRNA, complete cds. . -2.26 1.7E-19

85007 AK024076 MGC15875 cDNA FLJ14014 fis, clone HEMBA1000290. . -2.26 1.4E-15

10351 NM_007168 ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 (ABCA8) . -2.25 2.1E-05

84651 U47646 ECG2 clone N5-2 mRNA, 3' end. . -2.25 5.7E-03

1000 NM_001792 CDH2 cadherin 2, type 1, N-cadherin (neuronal) (CDH2) . -2.23 1.5E-11

80019 AK021869 UBTD1 cDNA FLJ11807 fis, clone HEMBA1006284. . -2.23 8.5E-10

1401 X56692 CRP C-reactive protein, pentraxin-related . -2.23 7.5E-11

7189 NM_004620 TRAF6 TNF receptor-associated factor 6 (TRAF6), transcript variant 2 . -2.21 6.7E-42

64399 AK024689 HHIP cDNA: FLJ21036 fis, clone CAE09578. . -2.21 3.0E-05

4502 NM_005953 MT2A metallothionein 2A (MT2A) . -2.20 9.3E-12

3987 NM_004987 LIMS1 LIM and senescent cell antigen-like domains 1 (LIMS1) . -2.20 8.1E-32

2088 X74613 ERVK3 H.sapiens HERV-K mRNA (252 bp). . -2.20 3.1E-05

4430 AK000160 MYO1B cDNA FLJ20153 fis, clone COL08656, highly similar to AJ001381 incomplete cDNA for a mutated allele. . -2.19 3.0E-04

55450 NM_018584 CaMKIINalpha calcium/calmodulin-dependent protein kinase II (CaMKIINalpha) . -2.19 1.7E-08

2202 NM_004105 EFEMP1 EGF-containing fibulin-like extracellular matrix protein 1 (EFEMP1), transcript variant 1 . -2.19 5.2E-18

9762 NM_014731 ProSAPiP1 ProSAPiP1 protein (ProSAPiP1) . -2.18 3.5E-13

3929 AF105067 LBP lipopolysaccharide-binding protein (LBP) mRNA, complete cds. . -2.18 1.2E-15

79143 S82470 LENG4 BB1=malignant cell expression-enhanced gene/tumor progression-enhanced gene [, UM-UC-9 bladder carcinoma ce . -2.16 4.3E-04

5340 NM_000301 PLG plasminogen (PLG) . -2.16 4.3E-04

56925 NM_020169 LXN latexin protein (LXN) . -2.16 5.5E-07

9397 NM_004808 NMT2 N-myristoyltransferase 2 (NMT2) . -2.15 1.9E-11

1522 NM_001336 CTSZ cathepsin Z (CTSZ) . -2.15 5.7E-06

4256 NM_000900 MGP matrix Gla protein (MGP) . -2.14 2.3E-12

4651 AF234532 MYO10 myosin X (MYO10) mRNA, complete cds. . -2.14 2.8E-20

9315 NM_004772 C5orf13 chromosome 5 open reading frame 13 (C5orf13) . -2.14 2.0E-34

1007 NM_016279 CDH9 cadherin 9, type 2 (T1-cadherin) (CDH9) . -2.13 3.8E-03

6772 NM_007315 STAT1 signal transducer and activator of transcription 1, 91kDa (STAT1), transcript variant alpha . -2.12 1.6E-09

26018 AL117666 LRIG1 mRNA; cDNA DKFZp586O1624 (from clone DKFZp586O1624); partial cds. . -2.12 5.3E-08

1811 NM_000111 SLC26A3 solute carrier family 26, member 3 (SLC26A3) . -2.10 5.3E-03

1010 NM_004061 CDH12 cadherin 12, type 2 (N-cadherin 2) (CDH12) . -2.10 2.4E-06

U92981 clone DT1P1B6 mRNA, CAG repeat region. . -2.10 8.3E-03

26118 NM_015626 WSB1 SOCS box-containing WD protein SWiP-1 (WSB1), transcript variant 1 . -2.10 6.4E-09

7044 NM_003240 LEFTY2 endometrial associated factor (left-right determination, factor A; transforming growth factor beta superfamily). -2.09 3.6E-14

23268 AB023227 DNMBP mRNA for KIAA1010 protein, partial cds. . -2.09 1.7E-07

5218 NM_012395 PFTK1 PFTAIRE protein kinase 1 (PFTK1) . -2.09 4.6E-06

5351 NM_000302 PLOD1 procollagen-, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase, Ehlers-Danlos syndrome type VI) (PLOD) . -2.09 2.3E-07 Page 3 / 11 Supplementary data: Genes repressed by KLF2 Dekker et al.

10656 NM_006558 KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 (KHDRBS3) . -2.08 2.9E-27

57520 AB037722 HECW2 mRNA for KIAA1301 protein, partial cds. . -2.07 1.5E-05

11178 AF123659 LZTS1 FEZ1 (FEZ1) mRNA, complete cds. . -2.07 5.8E-03

64781 AK026892 CERK cDNA: FLJ23239 fis, clone COL01248. . -2.07 3.0E-10

4733 NM_004147 DRG1 developmentally regulated GTP binding protein 1 (DRG1) . -2.06 4.5E-10

11228 NM_007211 C12orf2 chromosome 12 open reading frame 2 (C12orf2) . -2.04 6.1E-08

10321 NM_006061 CRISP3 -rich secretory protein 3 (CRISP3) . -2.04 4.0E-05

286334 AF147430 LOC286334 full length insert cDNA clone YP83B01. . -2.04 6.6E-07

57478 AB033029 USP31 mRNA for KIAA1203 protein, partial cds. . -2.04 2.1E-06

3788 AB032970 KCNS2 mRNA for KIAA1144 protein, partial cds. . -2.03 1.2E-08

3399 X69111 ID3 H.sapiens HLH 1R21 mRNA for helix-loop-helix protein. . -2.03 6.7E-10

27134 NM_014428 TJP3 tight junction protein 3 (zona occludens 3) (TJP3) . -2.02 3.6E-14

AF086187 full length insert cDNA clone ZC30H06. . -2.02 2.2E-06

9448 NM_004834 MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4), transcript variant 1 . -2.02 4.9E-07

AL109790 mRNA full length insert cDNA clone EUROIMAGE 1056496. . -2.00 4.5E-12

AF016004 m6b1 m6b1 mRNA, complete cds. . -2.00 1.3E-21

79842 AK027045 ZBTB3 cDNA: FLJ23392 fis, clone HEP17418. . -2.00 3.2E-11

1316 NM_001300 KLF6 core element binding protein (COPEB) . -1.99 6.6E-07

51308 NM_016606 C5orf19 SGC32445 protein (LOC51308) . -1.99 2.9E-07

8870 NM_003897 IER3 immediate early response 3 (IER3), transcript variant short . -1.98 1.4E-17

93663 AK002195 ARHGAP18 cDNA FLJ11333 fis, clone PLACE1010616. . -1.98 6.4E-03

860 L40992 RUNX2 (clone PEBP2aA1) core-binding factor, runt domain, alpha subunit 1 (CBFA1) mRNA, 3' end of cds. . -1.98 4.8E-06

51398 NM_016145 PTD008 PTD008 protein (PTD008) . -1.97 9.6E-07

4600 M30818 MX2 interferon-induced cellular resistance mediator protein (MxB) mRNA, complete cds. . -1.97 2.3E-09

65249 AK024452 ZSWIM4 mRNA for FLJ00044 protein, partial cds. . -1.97 3.1E-09

X04236 small cellular 7 SK mRNA. . -1.96 1.1E-08

219928 AL049451 MRGPRF mRNA; cDNA DKFZp586B2122 (from clone DKFZp586B2122). . -1.95 5.2E-03

23332 U62822 CLASP1 small nuclear RNA U4atac, partial sequence. . -1.95 9.6E-10

273 NM_001635 AMPH amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen) (AMPH), transcript variant 1 . -1.95 9.2E-04

10249 NM_005838 GLYAT -N-acyltransferase (GLYAT), nuclear gene encoding mitochondrial protein . -1.95 8.6E-10

10668 NM_006568 CGRRF1 cell growth regulator with ring finger domain 1 (CGRRF1) . -1.95 3.6E-09

10962 NM_006818 AF1Q ALL1-fused gene from chromosome 1q (AF1Q) . -1.94 2.3E-31

1794 D86964 DOCK2 mRNA for KIAA0209 gene, partial cds. . -1.94 3.6E-05

79772 AK025997 MCTP1 cDNA: FLJ22344 fis, clone HRC06080. . -1.94 4.0E-13

4500 X97261 MT1L H.sapiens mRNA for metallothionein isoform 1R. . -1.94 1.3E-25

89796 AB032977 NAV1 mRNA for KIAA1151 protein, partial cds. . -1.93 3.0E-04

3953 NM_002303 LEPR leptin receptor (LEPR) . -1.93 7.3E-03

5241 NM_000926 PGR (PGR) . -1.93 5.6E-03

57580 AB037836 PREX1 mRNA for KIAA1415 protein, partial cds. . -1.93 1.0E-15

4017 NM_002318 LOXL2 lysyl oxidase-like 2 (LOXL2) . -1.93 6.1E-10

Z36780 H.sapiens (xs122) mRNA, 160bp. . -1.92 3.7E-12 Page 4 / 11 Supplementary data: Genes repressed by KLF2 Dekker et al.

8835 NM_003877 SOCS2 suppressor of cytokine signaling 2 (SOCS2) . -1.92 4.1E-03

7852 NM_003467 CXCR4 chemokine (C-X-C motif) receptor 4 (CXCR4) . -1.92 4.3E-04

6288 NM_000331 SAA1 serum amyloid A1 (SAA1) . -1.91 2.3E-09

7763 NM_006007 ZA20D2 protein 216 (ZNF216) . -1.91 1.9E-19

83439 AB031046 TCF7L1 mRNA for HMG-box transcription factor TCF-3, complete cds. . -1.90 5.6E-05

55075 AB046781 UACA mRNA for KIAA1561 protein, partial cds. . -1.90 3.4E-06

3714 NM_002226 JAG2 jagged 2 (JAG2), transcript variant 1 . -1.90 6.7E-42

56300 NM_019618 IL1F9 interleukin 1 family, member 9 (IL1F9) . -1.90 7.0E-08

2631 NM_001483 GBAS glioblastoma amplified sequence (GBAS) . -1.90 5.1E-05

AF143882 unknown clone IMAGE:121214 mRNA sequence. . -1.90 1.8E-10

11228 AK021604 C12orf2 cDNA FLJ11542 fis, clone HEMBA1002801. . -1.89 3.0E-04

79843 AK026399 FLJ22746 cDNA: FLJ22746 fis, clone HUV01174. . -1.89 8.0E-04

9411 NM_004815 PARG1 PTPL1-associated RhoGAP 1 (PARG1) . -1.89 1.8E-22

4082 NM_002356 MARCKS myristoylated alanine-rich protein kinase C substrate (MARCKS) . -1.89 7.3E-14

51735 NM_016340 RAPGEF6 PDZ domain containing guanine nucleotide exchange factor (GEF) 2 (PDZGEF2) . -1.88 4.3E-07

9671 NM_014653 KIAA0789 . -1.87 4.4E-06

2273 NM_001449 FHL1 four and a half LIM domains 1 (FHL1) . -1.87 1.4E-06

79660 AK024067 PPP1R3B cDNA FLJ14005 fis, clone Y79AA1002361, moderately similar to Rattus norvegicus mRNA for protein phosphatase 1. -1.86 3.0E-04

10434 NM_006330 LYPLA1 lysophospholipase I (LYPLA1) . -1.86 4.6E-17

10253 NM_005842 SPRY2 sprouty homolog 2 (Drosophila) (SPRY2) . -1.86 3.5E-06

92312 AK024097 LOC92312 cDNA FLJ14035 fis, clone HEMBA1004638. . -1.86 3.7E-06

NM_016064 MSRB2 pilin-like transcription factor (PILB) . -1.86 2.1E-05

2589 NM_020474 GALNT1 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) (GALNT1) . -1.86 2.1E-06

10916 U92544 MAGED2 hepatocellular carcinoma associated protein (JCL-1) mRNA, complete cds. . -1.86 5.0E-07

M73547 DP1 polyposis (DP1 gene) mRNA, complete cds. . -1.86 4.3E-33

7035 NM_006287 TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) (TFPI) . -1.85 8.0E-03

57716 AB046840 PRX mRNA for KIAA1620 protein, partial cds. . -1.85 1.1E-04

5337 AK026225 PLD1 cDNA: FLJ22572 fis, clone HSI02313. . -1.85 6.0E-13

54407 AF116620 SLC38A2 PRO1068 mRNA, complete cds. . -1.85 9.2E-04

1006 NM_001796 CDH8 cadherin 8, type 2 (CDH8) . -1.85 7.0E-03

6659 NM_003107 SOX4 SRY (sex determining region Y)-box 4 (SOX4) . -1.84 2.1E-20

10741 NM_006606 RBBP9 retinoblastoma binding protein 9 (RBBP9), transcript variant 1 . -1.84 6.7E-42

3956 NM_002305 LGALS1 lectin, galactoside-binding, soluble, 1 (galectin 1) (LGALS1) . -1.84 3.6E-06

196 NM_001621 AHR aryl hydrocarbon receptor (AHR) . -1.84 3.1E-11

122704 AK000450 MRPL52 cDNA FLJ20443 fis, clone KAT05031. . -1.83 1.0E-04

4588 U97698 MUC6 secretory mucin MUC6 (MUC6) mRNA, partial cds. . -1.83 8.2E-13

26086 AL117478 GPSM1 mRNA; cDNA DKFZp727I051 (from clone DKFZp727I051); partial cds. . -1.83 6.5E-14

4628 M69181 MYH10 nonmuscle myosin heavy chain-B (MYH10) mRNA, partial cds. . -1.83 2.2E-06

5806 NM_002852 PTX3 pentaxin-related gene, rapidly induced by IL-1 beta (PTX3) . -1.83 8.8E-08

81557 AF320908 MAGED4 MAGE-D4 (MAGED4) mRNA, partial cds. . -1.82 2.2E-10

5352 NM_000935 PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase) 2 (PLOD2), transcript variant 2 . -1.82 7.3E-08 Page 5 / 11 Supplementary data: Genes repressed by KLF2 Dekker et al.

AK021457 cDNA FLJ11395 fis, clone HEMBA1000594. . -1.81 2.6E-03

8407 NM_003564 TAGLN2 transgelin 2 (TAGLN2) . -1.81 3.3E-03

4603 X66087 MYBL1 H.sapiens a- mRNA. . -1.81 1.2E-04

25822 NM_012266 DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5 (DNAJB5) . -1.81 1.4E-11

64093 AJ249900 SMOC1 mRNA for secreted modular calcium-binding protein (smoc1 gene). . -1.81 3.6E-05

NM_016214 COL18A1 collagen, type XVIII, alpha 1 (COL18A1), transcript variant 1 . -1.80 8.2E-08

4644 U90942 MYO5A myosin heavy chain 12 (MYO5A) mRNA, complete cds. . -1.80 3.9E-05

800 AF247820 CALD1 NAG22 protein mRNA, complete cds. . -1.79 4.9E-03

5567 NM_002731 PRKACB protein kinase, cAMP-dependent, catalytic, beta (PRKACB), transcript variant 2 . -1.79 3.0E-04

64750 AF301463 SMURF2 ubiquitin E3 ligase SMURF2 (SMURF2) mRNA, complete cds. . -1.78 2.7E-10

4082 AB020968 MARCKS mRNA, 3'UTR, up-regulated by BCG-CWS. . -1.78 4.6E-14

57381 AJ276567 RHOJ partial mRNA for TC10-like Rho GTPase (TCL gene). . -1.78 2.3E-35

63027 AL110245 C6orf85 mRNA; cDNA DKFZp434F011 (from clone DKFZp434F011); partial cds. . -1.78 5.1E-12

974 M89957 CD79B immunoglobulin superfamily member B cell receptor complex cell surface glycoprotein (IGB) mRNA, complete cds. . -1.78 1.6E-06

11098 NM_007173 PRSS23 protease, serine, 23 (SPUVE) . -1.77 1.3E-12

2953 NM_000854 GSTT2 glutathione S-transferase theta 2 (GSTT2) . -1.77 6.7E-42

10085 NM_005711 EDIL3 EGF-like repeats and discoidin I-like domains 3 (EDIL3) . -1.77 3.0E-03

5142 NM_002600 PDE4B phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila) (PDE4B) . -1.77 2.4E-10

5890 AF132200 RAD51L1 PRO1751 mRNA, complete cds. . -1.77 4.9E-06

3690 NM_000212 ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) (ITGB3) . -1.77 4.3E-04

4282 NM_002415 MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) (MIF) . -1.77 2.7E-05

23138 AB002339 N4BP3 mRNA for KIAA0341 gene, partial cds. . -1.76 3.6E-03

147991 AK024775 LOC147991 cDNA: FLJ21122 fis, clone CAS05917. . -1.76 1.9E-12

669 NM_001724 BPGM 2,3-bisphosphoglycerate mutase (BPGM) . -1.76 5.2E-06

55568 AK021777 GALNT10 cDNA FLJ11715 fis, clone HEMBA1005223. . -1.76 1.6E-04

1613 NM_001348 DAPK3 death-associated protein kinase 3 (DAPK3) . -1.75 9.6E-20

5663 NM_007318 PSEN1 presenilin 1 (Alzheimer disease 3) (PSEN1), transcript variant I-463 . -1.75 1.6E-10

2707 AF052692 GJB3 connexin 31 (GJB3) mRNA, complete cds. . -1.75 8.0E-04

122786 AK021747 C14orf31 cDNA FLJ11685 fis, clone HEMBA1004934. . -1.75 6.8E-03

1601 NM_001343 DAB2 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) (DAB2) . -1.75 3.1E-09

9902 NM_006039 MRC2 mannose receptor, C type 2 (MRC2) . -1.74 3.8E-07

55062 NM_017983 WIPI49 hypothetical protein FLJ10055 (FLJ10055) . -1.74 3.0E-04

NM_017862 . -1.74 4.6E-06

80243 AK023631 cDNA FLJ13569 fis, clone PLACE1008369. . -1.74 2.1E-08

64127 AF178930 CARD15 NOD2 protein (NOD2) mRNA, complete cds. . -1.73 5.6E-04

2687 NM_004121 GGTLA1 gamma-glutamyltransferase-like activity 1 (GGTLA1) . -1.73 7.4E-05

220112 AF075011 CTAGE3 full length insert cDNA YI08B08. . -1.73 6.8E-05

1232 NM_001837 CCR3 chemokine (C-C motif) receptor 3 (CCR3), transcript variant 1 . -1.73 1.1E-08

637 NM_001196 BID BH3 interacting domain death agonist (BID), transcript variant 2 . -1.73 1.6E-04

6611 NM_004595 SMS spermine synthase (SMS) . -1.73 1.3E-03

29890 NM_013286 RBM15B chromosome 3p21.1 gene sequence (HUMAGCGB) . -1.73 1.6E-06 Page 6 / 11 Supplementary data: Genes repressed by KLF2 Dekker et al.

3199 AL079274 HOXA2 mRNA full length insert cDNA clone EUROIMAGE 345330. . -1.73 2.0E-03

9110 AF264717 MTMR4 FYVE domain-containing dual specificity protein phosphatase FYVE-DSP2 mRNA, complete cds. . -1.73 1.6E-04

2779 NM_000172 GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 (GNAT1), transcript variant 2 . -1.73 1.1E-05

1627 NM_004395 DBN1 drebrin 1 (DBN1), transcript variant 1 . -1.72 2.1E-03

23365 NM_015313 ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 (ARHGEF12) . -1.72 3.6E-14

S70385 c-=Burkitt-like c-myc {exons 1 and 2, oncogene} [, prolymphocytic leukemia patient, mRNA Partial Mutant, 80 nt, . -1.72 2.1E-06

AY007090 clone TCCCIA00112 mRNA sequence. . -1.71 1.4E-03

10525 NM_006389 HYOU1 hypoxia up-regulated 1 (HYOU1) . -1.71 8.7E-08

1942 NM_004428 EFNA1 ephrin-A1 (EFNA1), transcript variant 1 . -1.71 4.0E-09

9537 NM_006034 TP53I11 tumor protein inducible protein 11 (TP53I11) . -1.71 4.4E-09

388 NM_004040 RHOB ras homolog gene family, member B (ARHB) . -1.71 1.9E-18

6459 AL359623 SH3GLP2 mRNA; cDNA DKFZp761J182 (from clone DKFZp761J182). . -1.71 8.1E-06

AF147337 full length insert cDNA clone YB26C09. . -1.70 7.5E-03

55135 NM_018081 FLJ10385 hypothetical protein FLJ10385 (FLJ10385) . -1.70 2.2E-03

26049 AB020695 KIAA0888 mRNA for KIAA0888 protein, partial cds. . -1.70 2.4E-03

1974 S67154 EIF4A2 E3 snRNA, E3 snRNA {intron 8} [, snRNA, 135 nt]. . -1.70 5.4E-08

10982 U90437 MAPRE2 RP1 homolog mRNA, 3'UTR region. . -1.70 2.9E-08

1036 NM_001801 CDO1 cysteine dioxygenase, type I (CDO1) . -1.70 8.0E-04

858 NM_001233 CAV2 caveolin 2 (CAV2) . -1.70 8.5E-08

2977 NM_000855 GUCY1A2 guanylate cyclase 1, soluble, alpha 2 (GUCY1A2) . -1.70 2.5E-06

9315 AK021624 C5orf13 cDNA FLJ11562 fis, clone HEMBA1003197. . -1.70 9.0E-08

64283 AK025470 RGNEF cDNA: FLJ21817 fis, clone HEP01141. . -1.70 1.0E-09

8793 NM_003840 TNFRSF10D receptor superfamily, member 10d, decoy with truncated death domain (TNFRSF10D) . -1.70 5.1E-05

26036 AK023072 ZNF451 cDNA FLJ13010 fis, clone NT2RP3000542. . -1.69 3.2E-03

2358 NM_001462 FPRL1 formyl peptide receptor-like 1 (FPRL1) . -1.69 8.2E-03

3726 NM_002229 JUNB jun B proto-oncogene (JUNB) . -1.69 5.0E-11

5731 NM_000955 PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa (PTGER1) . -1.69 8.3E-08

51177 NM_016274 CKIP-1 CK2 interacting protein 1; HQ0024c protein (CKIP-1) . -1.69 3.2E-05

10184 D86961 LHFPL2 mRNA for KIAA0206 gene, partial cds. . -1.69 7.9E-03

6622 NM_000345 SNCA synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant NACP140 . -1.69 3.1E-14

10395 NM_006094 DLC1 deleted in liver cancer 1 (DLC1), transcript variant 2 . -1.69 4.3E-09

AF085838 full length insert cDNA clone YI44D08. . -1.68 1.0E-03

2744 NM_014905 GLS glutaminase (GLS) . -1.68 3.0E-04

10417 NM_012445 SPON2 spondin 2, extracellular matrix protein (SPON2) . -1.68 4.3E-04

10105 NM_005729 PPIF peptidylprolyl isomerase F (cyclophilin F) (PPIF) . -1.68 9.3E-08

4988 NM_000914 OPRM1 opioid receptor, mu 1 (OPRM1) . -1.68 1.0E-03

6319 NM_005063 SCD stearoyl-CoA desaturase (delta-9-desaturase) (SCD) . -1.68 1.2E-04

875 NM_000071 CBS cystathionine-beta-synthase (CBS) . -1.68 4.3E-04

4065 NM_002349 LY75 antigen 75 (LY75) . -1.68 1.0E-05

800 NM_004342 CALD1 caldesmon 1 (CALD1), transcript variant 3 . -1.68 2.0E-06

9652 AF090944 KIAA0372 clone HQ0663 PRO0663 mRNA, partial cds. . -1.67 8.8E-03 Page 7 / 11 Supplementary data: Genes repressed by KLF2 Dekker et al.

51313 NM_016613 DKFZp434L142 hypothetical protein DKFZp434L142 (DKFZp434L142) . -1.67 1.9E-06

395 NM_001174 ARHGAP6 Rho GTPase activating protein 6 (ARHGAP6), transcript variant 2 . -1.67 4.4E-10

51098 NM_016004 C20orf9 chromosome 20 open reading frame 9 (C20orf9) . -1.67 2.0E-05

10536 NM_014262 LEPREL2 leprecan-like 2 protein (LEPREL2) . -1.67 1.6E-04

157680 NM_017890 COH1 Cohen syndrome 1 (COH1), transcript variant 5 . -1.67 5.7E-05

9866 AB002296 TRIM66 mRNA for KIAA0298 protein, partial cds. . -1.67 5.9E-05

8507 NM_003633 ENC1 ectodermal-neural cortex (with BTB-like domain) (ENC1) . -1.67 5.3E-08

91768 AK025627 CABLES1 cDNA: FLJ21974 fis, clone HEP05861. . -1.66 2.9E-05

57761 AK026945 TRIB3 cDNA: FLJ23292 fis, clone HEP10334. . -1.66 4.1E-03

55201 NM_018174 BPY2IP1 VCY2 interacting protein 1 (VCY2IP1) . -1.66 8.6E-26

5139 AK000795 PDE3A cDNA FLJ20788 fis, clone COL02074. . -1.66 8.8E-03

83881 AF211891 MIXL1 Mix.1 -like protein (MIXL) mRNA, complete cds. . -1.66 6.9E-04

57134 NM_020379 MAN1C1 mannosidase, alpha, class 1C, member 1 (MAN1C1) . -1.66 1.2E-05

7097 NM_003264 TLR2 toll-like receptor 2 (TLR2) . -1.66 2.9E-03

X04547 tRNA-Met C5 RNA (tRNA-Met precursor) from HeLa cells. . -1.65 7.1E-06

D28381 osteonectin mRNA for osteonectin, 5'UTR (sequence from the 5'cap to the start codon). . -1.65 9.4E-06

55711 NM_018099 MLSTD1 hypothetical protein FLJ10462 (FLJ10462) . -1.65 4.1E-13

6529 NM_003042 SLC6A1 solute carrier family 6 (neurotransmitter transporter, GABA), member 1 (SLC6A1) . -1.65 9.8E-05

6236 NM_004165 RRAD Ras-related associated with diabetes (RRAD) . -1.65 3.7E-08

8318 U84526 CDC45L velo-cardio-facial syndrome 22q11 region mRNA sequence. . -1.65 3.5E-11

90627 AL049801 STARD13 Novel gene mapping to chomosome 13, similar to rat RhoGAP. . -1.65 3.8E-27

23362 NM_015310 PSD3 ADP-ribosylation factor guanine nucleotide factor 6 (EFA6R) . -1.65 3.2E-03

25940 AL049943 DKFZP564F052mRNA; cDNA DKFZp564F0522 (from clone DKFZp564F0522). . -1.65 8.0E-04

993 NM_001789 CDC25A cell division cycle 25A (CDC25A) . -1.65 8.8E-06

54860 NM_017716 MS4A12 membrane-spanning 4-domains, subfamily A, member 12 (MS4A12) . -1.65 4.2E-05

784 NM_000725 CACNB3 calcium channel, voltage-dependent, beta 3 subunit (CACNB3) . -1.65 1.4E-04

153811 AK021734 LOC153811 cDNA FLJ11672 fis, clone HEMBA1004733. . -1.65 3.9E-03

7570 NM_006963 ZNF22 zinc finger protein 22 (KOX 15) (ZNF22) . -1.65 6.9E-04

4323 NM_004995 MMP14 matrix metalloproteinase 14 (membrane-inserted) (MMP14) . -1.65 3.0E-04

9749 NM_014721 PHACTR2 chromosome 6 open reading frame 56 (C6orf56) . -1.65 8.4E-03

AF086319 full length insert cDNA clone ZD53C05. . -1.65 3.6E-14

1809 NM_001387 DPYSL3 dihydropyrimidinase-like 3 (DPYSL3) . -1.64 2.2E-08

140688 AL122043 C20orf112 mRNA; cDNA DKFZp566G1424 (from clone DKFZp566G1424). . -1.64 6.6E-09

7204 NM_007118 TRIO triple functional domain (PTPRF interacting) (TRIO) . -1.64 7.3E-06

AF052109 clone 23927 mRNA sequence. . -1.64 1.3E-08

27023 AF071554 FOXB1 forkhead/winged helix transcription factor Fkh5 (FKH5) mRNA, complete cds. . -1.64 1.4E-03

5998 AF131806 RGS3 clone 24863 mRNA sequence. . -1.64 1.4E-03

80196 AK025439 RNF34 cDNA: FLJ21786 fis, clone HEP00326. . -1.64 9.7E-05

8661 AL390137 EIF3S10 mRNA; cDNA DKFZp547C074 (from clone DKFZp547C074). . -1.63 3.0E-04

51701 U00949 NLK clone C4E 5.3 (CAC)n/(GTG)n repeat-containing mRNA. . -1.63 2.8E-03

6510 NM_005628 SLC1A5 solute carrier family 1 (neutral transporter), member 5 (SLC1A5) . -1.63 4.6E-03 Page 8 / 11 Supplementary data: Genes repressed by KLF2 Dekker et al.

483 NM_001679 ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide (ATP1B3) . -1.63 4.3E-04

51009 NM_016041 DERL2 carcinoma related gene (F-LANa) . -1.63 2.6E-22

5654 NM_002775 PRSS11 protease, serine, 11 (IGF binding) (PRSS11) . -1.63 5.6E-04

51705 AL133118 EMCN mRNA; cDNA DKFZp586N0121 (from clone DKFZp586N0121). . -1.63 4.3E-07

10769 NM_006622 PLK2 serum-inducible kinase (SNK) . -1.63 4.5E-25

3263 J03048 HPX Huma hemopexin mRNA, 3' end. . -1.62 8.2E-06

22822 NM_007350 PHLDA1 pleckstrin homology-like domain, family A, member 1 (PHLDA1) . -1.62 2.6E-03

266727 AF087987 MDGA1 full length insert cDNA clone YX25D06. . -1.62 6.9E-04

4071 X75684 TM4SF1 H.sapiens (TL27) mRNA from (PC3) cell line. . -1.62 5.4E-13

79819 AK021936 FLJ23129 cDNA FLJ11874 fis, clone HEMBA1007073. . -1.62 1.5E-05

54407 NM_018976 SLC38A2 solute carrier family 38, member 2 (SLC38A2) . -1.62 1.1E-05

6397 NM_003003 SEC14L1 SEC14-like 1 (S. cerevisiae) (SEC14L1) . -1.62 8.8E-06

786 NM_000727 CACNG1 calcium channel, voltage-dependent, gamma subunit 1 (CACNG1) . -1.61 1.1E-04

64321 AK025905 SOX17 cDNA: FLJ22252 fis, clone HRC02734. . -1.61 3.2E-07

10516 NM_006329 FBLN5 fibulin 5 (FBLN5) . -1.61 1.6E-09

152485 AL117519 LOC152485 mRNA; cDNA DKFZp434P0235 (from clone DKFZp434P0235). . -1.61 4.0E-03

10570 AB006713 DPYSL4 mRNA for dihydropyrimidinase related protein 4, complete cds. . -1.61 6.0E-06

148206 D70836 LOC148206 mRNA for Zinc-finger protein, partial cds. . -1.61 4.0E-07

6150 U26596 MRPL23 ribosomal protein L23-related mRNA, complete cds. . -1.61 1.6E-05

27145 AB033101 FILIP1 mRNA for KIAA1275 protein, partial cds. . -1.61 5.6E-04

3447 NM_006900 IFNA13 interferon, alpha 13 (IFNA13) . -1.61 3.4E-03

8993 NM_005091 PGLYRP1 peptidoglycan recognition protein (PGLYRP) . -1.61 2.1E-05

5868 NM_004162 RAB5A RAB5A, member RAS oncogene family (RAB5A) . -1.61 1.8E-11

3091 NM_001530 HIF1A hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) (HIF1A), transcript variant 1 . -1.61 5.9E-07

199 NM_004847 AIF1 allograft inflammatory factor 1 (AIF1), transcript variant 2 . -1.60 3.6E-05

1879 AF208502 EBF early B-cell transcription factor (EBF) mRNA, partial cds. . -1.60 1.1E-03

22907 NM_014966 DHX30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 (DHX30), transcript variant 2 . -1.60 3.4E-06

57060 NM_020418 PCBP4 poly(rC) binding protein 4 (PCBP4), transcript variant 1 . -1.60 6.5E-10

79784 AK023943 MYH14 cDNA FLJ13881 fis, clone THYRO1001458, moderately similar to MYOSIN HEAVY CHAIN, NONMUSCLE TYPE B. . -1.60 4.2E-03

664 NM_004052 BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 (BNIP3), nuclear gene encoding mitochondrial protein . -1.60 1.5E-05

4814 NM_004148 NINJ1 ninjurin 1 (NINJ1) . -1.60 9.7E-14

U05589 ribosomal protein S1 homolog mRNA, partial cds. . -1.59 2.2E-05

6556 D50402 SLC11A1 mRNA for NRAMP1, complete cds. . -1.59 1.5E-13

1525 NM_001338 CXADR coxsackie virus and adenovirus receptor (CXADR) . -1.59 3.6E-05

S82164 ER ER= {exon 5 to exon 6, intervening sequence} [, breast cancer biopsy, breast cancer patient, mRNA. -1.59 4.4E-03

7328 AK026094 UBE2H cDNA: FLJ22441 fis, clone HRC09331. . -1.59 2.9E-07

3954 NM_012318 LETM1 -EF-hand containing transmembrane protein 1 (LETM1) . -1.59 9.2E-04

5423 NM_002690 POLB polymerase (DNA directed), beta (POLB) . -1.58 8.7E-03

83604 AL049257 TM4SF10 mRNA; cDNA DKFZp564E153 (from clone DKFZp564E153). . -1.58 4.8E-05

2657 NM_001492 GDF1 growth differentiation factor 1 (GDF1) . -1.58 7.6E-03

6677 S67798 SPAM1 PH-20 (SPAM1) mRNA, complete cds. . -1.58 4.5E-06 Page 9 / 11 Supplementary data: Genes repressed by KLF2 Dekker et al.

79966 AK024685 SCD4 cDNA: FLJ21032 fis, clone CAE07365. . -1.58 1.0E-03

9052 AK024522 GPCR5A cDNA: FLJ20869 fis, clone ADKA02377. . -1.58 3.4E-03

AL117546 mRNA; cDNA DKFZp586C1923 (from clone DKFZp586C1923). . -1.57 9.0E-11

29964 AK023682 C6orf49 cDNA FLJ13620 fis, clone PLACE1010947. . -1.57 1.8E-08

2324 S66407 FLT4 FLT4=receptor kinase isoform FLT4 long {3' region, alternatively spliced} [, mRNA Partial, 216 nt]. . -1.57 8.3E-11

11086 NM_014269 ADAM29 a disintegrin and metalloproteinase domain 29 (ADAM29), transcript variant 1 . -1.57 5.0E-06

22986 AB028982 SORCS3 mRNA for KIAA1059 protein, partial cds. . -1.57 2.0E-05

7041 NM_015927 TGFB1I1 transforming growth factor beta 1 induced transcript 1 (TGFB1I1) . -1.57 5.1E-05

10750 NM_006613 GRAP GRB2-related adaptor protein (GRAP) . -1.57 6.0E-06

22846 NM_014909 KIAA1036 KIAA1036 protein (KIAA1036) . -1.57 1.7E-03

9732 NM_014705 DOCK4 DOCK4 (DOCK4) . -1.57 2.9E-03

6480 NM_003032 SIAT1 sialyltransferase 1 (beta-galactoside alpha-2,6-sialyltransferase) (SIAT1), transcript variant 2 . -1.57 5.7E-03

64208 AF204171 POPDC3 clone IMAGE:249526 popeye protein 3 (POP3) mRNA, complete cds. . -1.57 7.3E-07

10492 NM_006372 SYNCRIP NS1-associated protein 1 (NSAP1) . -1.56 2.4E-03

56935 NM_020179 FN5 FN5 protein (FN5) . -1.56 1.7E-03

4477 NM_002443 MSMB microseminoprotein, beta- (MSMB), transcript variant PSP94 . -1.56 5.6E-04

3096 NM_002114 HIVEP1 immunodeficiency virus type I enhancer binding protein 1 (HIVEP1) . -1.56 7.6E-03

56833 NM_020125 SLAMF8 B lymphocyte activator macrophage expressed (BLAME) . -1.56 3.0E-04

1611 AF056450 DAP clone TEA9 Cri-du-chat critical region mRNA. . -1.56 1.0E-03

3572 AL049265 IL6ST mRNA; cDNA DKFZp564F053 (from clone DKFZp564F053). . -1.56 6.1E-06

4992 NM_012360 OR1F1 olfactory receptor, family 1, subfamily F, member 1 (OR1F1) . -1.56 8.0E-03

5831 NM_006907 PYCR1 pyrroline-5-carboxylate reductase 1 (PYCR1), transcript variant 1 . -1.55 2.3E-06

2673 NM_002056 GFPT1 glutamine-fructose-6-phosphate transaminase 1 (GFPT1) . -1.55 8.5E-03

M29212 Th RNA, complete cds. . -1.55 6.1E-03

26784 Y11158 RNU64 H.sapiens U64 small nucleolar RNA gene. . -1.55 1.7E-07

22877 NM_014938 MONDOA Mlx interactor (MONDOA) . -1.55 6.1E-07

2131 NM_000127 EXT1 exostoses (multiple) 1 (EXT1) . -1.55 1.4E-03

NM_016435 . -1.55 3.3E-03

10608 NM_006454 MXD4 MAX dimerization protein 4 (MXD4) . -1.55 5.8E-06

10461 NM_006343 MERTK c-mer proto-oncogene tyrosine kinase (MERTK) . -1.55 4.3E-10

5918 NM_002888 RARRES1 responder (tazarotene induced) 1 (RARRES1) . -1.55 1.4E-07

55837 NM_018453 C14orf11 open reading frame 11 (C14orf11) . -1.54 3.0E-04

6840 NM_003174 SVIL supervillin (SVIL), transcript variant 1 . -1.54 2.7E-08

2195 NM_005245 FAT FAT tumor suppressor homolog 1 (Drosophila) (FAT) . -1.54 1.1E-05

6857 NM_005639 SYT1 synaptotagmin I (SYT1) . -1.54 8.0E-04

26247 X64980 OR2L1P H.sapiens mRNA HTPCRX02 for olfactory receptor. . -1.54 3.6E-14

120 NM_016824 ADD3 adducin 3 (gamma) (ADD3), transcript variant 1 . -1.54 4.5E-05

7466 NM_006005 WFS1 Wolfram syndrome 1 (wolframin) (WFS1) . -1.54 1.5E-03

79577 AK026969 HRPT2 cDNA: FLJ23316 fis, clone HEP12031. . -1.54 5.1E-03

29109 NM_013241 FHOD1 formin homology 2 domain containing 1 (FHOD1) . -1.53 8.2E-06

11314 AF020314 CMRF-35H CMRF-35-H9 mRNA, complete cds. . -1.53 8.0E-04 Page 10 / 11 Supplementary data: Genes repressed by KLF2 Dekker et al.

10295 NM_005881 BCKDK branched chain alpha-ketoacid dehydrogenase kinase (BCKDK) . -1.53 1.1E-05

5519 AF163473 PPP2R1B protein phosphatase 2A regulatory subunit A beta isoform (PPP2R1B) mRNA, complete cds. . -1.53 2.2E-03

6001 AF045229 RGS10 regulator of G protein signaling 10 mRNA, complete cds. . -1.53 1.1E-09

55088 AK024739 C10orf118 cDNA: FLJ21086 fis, clone CAS03272. . -1.53 9.2E-04

58527 AF116682 C6orf115 PRO2013 mRNA, complete cds. . -1.53 1.4E-04

8362 NM_003541 HIST1H4K histone 1, H4k (HIST1H4K) . -1.53 4.3E-04

608 NM_001192 TNFRSF17 tumor necrosis factor receptor superfamily, member 17 (TNFRSF17) . -1.53 5.4E-06

2335 AF130095 FN1 clone FLC0562 PRO2841 mRNA, complete cds. . -1.53 2.3E-08

5130 AF086176 PCYT1A full length insert cDNA clone ZB95G04. . -1.53 1.9E-03

9828 NM_014786 ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17 (ARHGEF17) . -1.52 9.6E-11

NM_016168 . -1.52 2.9E-09

55285 NM_018301 FLJ11016 hypothetical protein FLJ11016 (FLJ11016) . -1.52 8.4E-10

54456 AL133068 MOV10L1 mRNA; cDNA DKFZp434B0717 (from clone DKFZp434B0717). . -1.52 6.3E-03

9859 NM_014812 KAB KARP-1-binding protein (KAB) . -1.52 1.6E-09

54708 NM_017824 RNF153 hypothetical protein FLJ20445 (FLJ20445) . -1.52 1.8E-05

3713 NM_005547 IVL involucrin (IVL) . -1.52 1.5E-10

M92271 (clone uf22) dihydropyridine-sensitive calcium channel HFCC, 3' end intron 5. . -1.52 6.4E-03

1440 NM_000759 CSF3 colony stimulating factor 3 (granulocyte) (CSF3), transcript variant 1 . -1.52 5.6E-06

23515 D50926 ZCWCC3 mRNA for KIAA0136 gene, partial cds. . -1.52 6.7E-07

5530 NM_000944 PPP3CA protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) (PPP3CA) . -1.52 3.0E-04

7037 NM_003234 TFRC transferrin receptor (p90, CD71) (TFRC) . -1.52 7.8E-06

55691 NM_018027 FRMD4A hypothetical protein FLJ10210 (FLJ10210) . -1.52 4.6E-24

10283 NM_005869 SDCCAG10 serologically defined colon cancer antigen 10 (SDCCAG10) . -1.51 3.7E-13

26775 Y11167 RNU72 H.sapiens U72 small nucleolar RNA gene. . -1.51 1.4E-03

6285 NM_006272 S100B S100 calcium binding protein, beta (neural) (S100B) . -1.51 2.0E-03

1602 NM_004392 DACH1 dachshund homolog (Drosophila) (DACH), transcript variant 3 . -1.51 2.5E-03

AF222023 uncharacterized gastric protein ZA31P mRNA, partial cds. . -1.51 1.5E-04

3577 NM_000634 IL8RA interleukin 8 receptor, alpha (IL8RA) . -1.51 4.2E-06

AK026181 cDNA: FLJ22528 fis, clone HRC12825. . -1.51 1.4E-04

56242 AF038951 ZNF253 DNA-binding protein mRNA, complete cds. . -1.51 4.7E-03

4217 NM_005923 MAP3K5 mitogen-activated protein kinase kinase kinase 5 (MAP3K5) . -1.50 5.3E-08

81671 AK024969 VMP1 cDNA: FLJ21316 fis, clone COL02253, highly similar to AF161410 HSPC292 mRNA. . -1.50 5.1E-03

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