Anti-Infective Drugs Created by the Njardarson Group (The University of Arizona): Edon Vitaku, Elizabeth A. Ilardi, Daniel J. Mack, Monica A. Fallon, Erik B. Gerlach, Miyant’e Y. Newton, Angela N. Yazzie, Jón T. Njarðarson

Streptozol Spectam Novocain Sulfadiazine M&B Streptomycin Chloromycetin Terramycin Tetracyn Seromycin Tubizid Illosone Furadantin Ethina Vancocin Polymyxin E Viderabin Declomycin Sulfamethizole Blephamide S.O.P. ( Sulfanilamide ) ( Spectinomycin ) ( Procaine ) ( Sulfadiazine ) ( Sulfapyridine ) ( Streptomycin ) ( Chloramphenicol ) ( Oxytetracycline ) ( Tetracycline ) ( Cycloserine ) ( Isoniazid ) ( Erythromycin ) ( Nitrofurantoin ) ( Ethionamide ) ( Vancomycin ) ( Colistin ) ( Vidarabine ) ( Demeclocycline ) ( Sulfamethizole ) ( Prednisolone Acetate & Sulfacetamide )

ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIMYCOBACTERIAL ANTIMYCOBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIMYCOBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIVIRAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL Approved 1937 Approved 1937 Approved 1939 Approved 1941 Approved 1942 Approved 1946 Approved 1949 Approved 1950 Approved 1950s Approved 1950s Approved 1952 Approved 1953 Approved 1953 Approved 1956 Approved 1958 Approved 1959 Approved 1960 Approved 1960 Approved 1960s Approved 1961

Coly-Mycin S Caprocin Poly-Pred Aureocarmyl Stoxil Flagyl NegGram Neomycin Flumadine Omnipen Neosporin G.U. Clomocycline Versapen-K Fungizone Vibramycin Myambutol Pathocil Cleocin Gentak Floxapen ( Neomycin, Colistin, Hydrocortisone Acetate & Thonzonium ) ( Capreomycin ) ( Neomycin, Polymyxin B & Prednisolone Acetate ) ( Lymecycline ) ( Idoxuridine ) ( Metronidazole ) ( Nalidixic Acid ) ( Neomycin ) ( Rimantadine ) ( Ampicillin ) ( Neomycin & Polymyxin B ) ( Clomocycline ) ( Hetacillin ) ( Amphotericin B ) ( Doxycycline ) ( Ethambutol ) ( Dicloxacillin ) ( Clindamycin ) ( Gentamicin ) ( Flucloxacillin )

ANTIBACTERIAL ANTIMYCOBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIVIRAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIVIRAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIMYCOTIC ANTIBACTERIAL ANTIMYCOBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL Approved 1962 Approved 1962 Approved 1963 Approved 1963 Approved 1963 Approved 1963 Approved 1964 Approved 1964 Approved 1965 Approved 1965 Approved 1966 Approved 1966 Approved 1966 Approved 1966 Approved 1967 Approved 1967 Approved 1968 Approved 1970 Approved 1970 Approved 1970s

Keflex Oxacillin Minocin Veetids Pyrazinamide Ancobon Bactrim Kantrex Trimox Cloxapen Monistat 7 Rifamate Nebcin Geocillin Duricef Ceclor Dapsone Cinobac Proloprim Pipracil ( Cephalexin ) ( Oxacillin ) ( Minocycline ) ( Penicillin V ) ( Pyrazinamide ) ( Flucytosine ) ( Trimethoprim & Sulfamethoxazole ) ( Kanamycin ) ( Amoxicillin ) ( Cloxacillin ) ( Miconazole ) ( Isoniazid & Rifampin ) ( Tobramycin ) ( Carbenicillin ) ( Cefadroxil ) ( Cefaclor ) ( Dapsone ) ( Cinoxacin ) ( Trimethoprim ) ( Piperacillin )

ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIMYCOBACTERIAL ANTIMYCOTIC ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIMYCOTIC ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIMYCOBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL Approved 1971 Approved 1971 Approved 1971 Approved 1971 Approved 1971 Approved 1971 Approved 1973 Approved 1973 Approved 1974 Approved 1974 Approved 1974 Approved 1975 Approved 1975 Approved 1977 Approved 1978 Approved 1979 Approved 1979 Approved 1980 Approved 1980 Approved 1981

Claforan Nizoral Amikin Mezlin Sulfamethoxazole Aziocillin Polymyxin B Netromycin Zinacef Precef Rocephin Primaxin Timentin Fortaz Pefloxacine Rulid Virazole Unasyn Azactam Noroxin ( Cefotaxime ) ( Ketoconazole ) ( Amikacin ) ( Mezlocillin ) ( Sulfamethoxazole ) ( Azlocillin ) ( Polymyxin B ) ( Netilmicin ) ( Cefuroxime ) ( Ceforanide ) ( Ceftriaxone ) ( Cilastatin & Imipenem ) ( Clavulanate & Ticarcillin ) ( Ceftazidime ) ( Pefloxacin ) ( Roxithromycin ) ( Ribavirin ) ( Sulbactam & Ampicillin ) ( Aztreonam ) ( Norfloxacin )

ANTIBACTERIAL ANTIMYCOTIC ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIVIRAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL Approved 1981 Approved 1981 Approved 1981 Approved 1982 Approved 1982 Approved 1982 Approved 1983 Approved 1983 Approved 1983 Approved 1984 Approved 1984 Approved 1985 Approved 1985 Approved 1985 Approved 1985 Approved 1985 Approved 1985 Approved 1986 Approved 1986 Approved 1986

Lamprene Cefmax Retrovir Cipro Neosporin Pred-G Polytrim Ceradon Penicillin G Zefazone Cefpiramide Suprax Cytovene Diflucan Floxin Zithromax Lorabid Penetrex Biaxin Videx ( Clofazimine ) ( Cefmenoxime ) ( Zidovudine ) ( Ciprofloxacin ) ( Neomycin, Polymyxin B & Gramicidin ) ( Gentamicin & Prednisolone Acetate ) ( Trimethoprim & Polymyxin B ) ( Cefotiam ) ( Penicillin G ) ( Cefmetazole ) ( Cefpiramide ) ( Cefixime ) ( Ganciclovir ) ( Fluconazole ) ( Ofloxacin ) ( Azithromycin ) ( Loracarbef ) ( Enoxacin ) ( Clarithromycin ) ( Didanosine )

ANTIMYCOBACTERIAL ANTIBACTERIAL ANTIVIRAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIVIRAL ANTIMYCOTIC ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIVIRAL Approved 1986 Approved 1987 Approved 1987 Approved 1987 Approved 1987 Approved 1988 Approved 1988 Approved 1988 Approved 1988 Approved 1989 Approved 1989 Approved 1989 Approved 1989 Approved 1990 Approved 1990 Approved 1991 Approved 1991 Approved 1991 Approved 1991 Approved 1991

Cefzil Foscavir Maxaquin Mycobutin HIVID Sporanox Zosyn Rifater Paser Zerit Famvir Dynabac Epivir Invirase Merrem Monurol Levaquin Zagam Crixivan Viramune ( Cefprozil ) ( Foscarnet ) ( Lomefloxacin ) ( Rifabutin ) ( Zalcitabine ) ( Itraconazole ) ( Piperacillin & Tazobactam ) ( Isoniazid, Pyrazinamide & Rifampin ) ( Aminosalicylic Acid ) ( Stavudine ) ( Famciclovir ) ( Dirithromycin ) ( Lamivudine ) ( Saquinavir ) ( Meropenem ) ( Fosfomycin ) ( Levofloxacin ) ( Sparfloxacin ) ( Indinavir ) ( Nevirapine )

ANTIBACTERIAL ANTIVIRAL ANTIBACTERIAL ANTIMYCOBACTERIAL ANTIVIRAL ANTIMYCOTIC ANTIBACTERIAL ANTIBACTERIAL ANTIMYCOBACTERIAL ANTIVIRAL ANTIVIRAL ANTIBACTERIAL ANTIVIRAL ANTIVIRAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIVIRAL ANTIVIRAL Approved 1991 Approved 1991 Approved 1992 Approved 1992 Approved 1992 Approved 1992 Approved 1993 Approved 1994 Approved 1994 Approved 1994 Approved 1994 Approved 1995 Approved 1995 Approved 1995 Approved 1996 Approved 1996 Approved 1996 Approved 1996 Approved 1996 Approved 1996

Denavir Vistide Norvir Prevpac Raxar Omnicef Viracept Rescriptor Trovan Combivir Priftin Ziagen Sustiva Relenza Avelox Tamiflu Agenerase Zyvox Trizivir Kaletra ( Penciclovir ) ( Cidofovir ) ( Ritonavir ) ( Amoxicillin, Clarithromycin & Lansoprazole ) ( Grepafloxacin ) ( Cefdinir ) ( Nelfinavir ) ( Delavirdine ) ( Trovafloxacin ) ( Lamivudine & Zidovudine ) ( Rifapentine ) ( Abacavir ) ( Efavirenz ) ( Zanamivir ) ( Moxifloxacin ) ( Oseltamivir ) ( Amprenavir ) ( Linezolid ) ( Abacavir, Lamivudine & Zidovudine ) ( Lopinavir & Ritonavir )

ANTIVIRAL ANTIVIRAL ANTIVIRAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIVIRAL ANTIVIRAL ANTIBACTERIAL ANTIVIRAL ANTIMYCOBACTERIAL ANTIVIRAL ANTIVIRAL ANTIVIRAL ANTIBACTERIAL ANTIVIRAL ANTIVIRAL ANTIBACTERIAL ANTIVIRAL ANTIVIRAL Approved 1996 Approved 1996 Approved 1996 Approved 1997 Approved 1997 Approved 1997 Approved 1997 Approved 1997 Approved 1997 Approved 1997 Approved 1998 Approved 1998 Approved 1998 Approved 1999 Approved 1999 Approved 1999 Approved 1999 Approved 2000 Approved 2000 Approved 2000

Spectracef Cancidas INVanz Viread Vfend Hepsera Augmentin XR Zymar Factive Emtriva Reyataz Ketek Tindamax Epzicom Truvada Mycamine Baraclude Aptivus Eraxis Atripla ( Cefditoren Pivoxil ) ( Caspofungin ) ( Ertapenem ) ( Tenofovir ) ( Voriconazole ) ( Adefovir Dipivoxil ) ( Amoxicillin & Clavulanate ) ( Gatifloxacin ) ( Gemifloxacin ) ( Emtricitabine ) ( Atazanavir ) ( Telithromycin ) ( Tinidazole ) ( Abacavir & Lamivudine ) ( Emtricitabine & Tenofovir Disoproxil ) ( Micafungin ) ( Entecavir ) ( Tipranavir ) ( Anidulafungin ) ( Emtricitabine, Tenofovir Disoproxil & Efavirenz )

ANTIBACTERIAL ANTIMYCOTIC ANTIBACTERIAL ANTIVIRAL ANTIMYCOTIC ANTIVIRAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIVIRAL ANTIVIRAL ANTIBACTERIAL ANTIBACTERIAL ANTIVIRAL ANTIVIRAL ANTIMYCOTIC ANTIVIRAL ANTIVIRAL ANTIMYCOTIC ANTIVIRAL Approved 2001 Approved 2001 Approved 2001 Approved 2001 Approved 2002 Approved 2002 Approved 2002 Approved 2003 Approved 2003 Approved 2003 Approved 2003 Approved 2004 Approved 2004 Approved 2004 Approved 2004 Approved 2005 Approved 2005 Approved 2005 Approved 2006 Approved 2006

Isentress Selzentry Intelence Viread Besivance Vibativ Teflaro Natroba Victrelis Edurant Incivek Dificid Complera Stribild Sirturo Fulyzaq ( Raltegravir ) ( Maraviroc ) ( Etravirine ) ( Tenofovir Disoproxil ) ( Besifloxacin ) ( Telavancin ) ( Ceftaroline Fosamil ) ( Spinosad ) ( Boceprevir ) ( Rilpivirine ) ( Telaprevir ) ( Fidaxomicin ) ( Emtricitabine, Rilpivirine & Tenofovir Disoproxil ) ( Cobicistat, Elvitegravir, Emtricitabine & Tenofovir Disoproxil ) ( Bedaquiline ) ( Crofelemer )

ANTIVIRAL ANTIVIRAL ANTIVIRAL ANTIVIRAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIBACTERIAL ANTIVIRAL ANTIVIRAL ANTIVIRAL ANTIBACTERIAL ANTIVIRAL ANTIVIRAL ANTIBACTERIAL ANTIBACTERIAL Approved 2007 Approved 2007 Approved 2008 Approved 2008 Approved 2009 Approved 2009 Approved 2010 Approved 2011 Approved 2011 Approved 2011 Approved 2011 Approved 2011 Approved 2011 Approved 2012 Approved 2012 Approved 2012

All drugs are considered FDA approved in the U.S. following the passage of the Pure Food and Drugs Act in 1906. http://www.fda.gov/Drugs/InformationOnDrugs/ApprovedDrugs/