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CURRICULUM VITAE PERSONAL INFORMATION Name: David Robert Clemmons EDUCATION 1965-1966 Undergraduate, Vanderbilt University 1966

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CURRICULUM VITAE PERSONAL INFORMATION Name: David Robert Clemmons EDUCATION 1965-1966 Undergraduate, Vanderbilt University 1966 CURRICULUM VITAE PERSONAL INFORMATION Name: David Robert Clemmons EDUCATION 1965-1966 Undergraduate, Vanderbilt University 1966-1969 B.S., Davidson College 1970-1974 M.D. with honors, University of North Carolina at Chapel Hill Postgraduate: 1974-1975 Intern in Medicine, Massachusetts General Hospital 1975-1976 Junior Assistant Resident, Massachusetts General Hospital 1976-1977 Senior Assistant Resident, Johns Hopkins Hospital 1977-1978 Clinical Fellowship in Endocrinology, Massachusetts General Hospital 1978-1980 Research Fellow in Cell Biology, Massachusetts General Hospital and the University of North Carolina at Chapel Hill RESEARCH EXPERIENCE 1971-1972 USPHS Fellow in Pediatric Endocrinology 1978-1980 USPHS Fellow in Endocrinology FACULTY APPOINTMENTS 1980-1984 Assistant Professor of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC 1984-1989 Associate Professor of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC 1989-present Professor of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC 1990-2006 Chief, Division of Endocrinology, University of North Carolina School of Medicine, Chapel Hill, NC 1995-present Sarah Graham Kenan Professor of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC 2006-2009 Director, Diabetes Center for Excellence, University of North Carolina School of Medicine, Chapel Hill, NC TEACHING APPOINTMENTS 1974-1976 Clinical Fellow in Medicine, Harvard Medical School 1976-1977 Clinical Fellow in Medicine, Johns Hopkins Hospital 1977-1978 Clinical Fellow in Endocrinology, Harvard Medical School 1978-1980 Clinical and Research Fellow in Endocrinology, Harvard Medical School and the University of North Carolina at Chapel Hill HONORS 1973 Deborah Cushing Leary Award 1974 Alpha Omega Alpha 1974 M.D. with honors 1 1974 James Bell Bullitt Award (Outstanding Senior Medical Student) 1978 National Research Service Award 1983 Jefferson-Pilot Fellow in Academic Medicine 1986 American Society of Clinical Investigation 1990 Chairman, Cell Biology and Physiology Study Section 1992 Chairman, Gordon Research Conference on Peptide Growth Factors 1995 Association of American Physicians 1999 Pharmacia-Upjohn Award for the best paper in the Journal of Clinical Endocrinology and Metabolism for 1998 2000 Citation by the Institute Scientific Information for being one of the 250 most cited scientists in the world in the fields of biology/biochemistry and clinical medicine between 1981-2000 2004 MERIT Award National Institutes of Health 2005 Aurbach Award, Endocrine Society CERTIFICATION 1976 Diplomate, Internal Medicine (American Board of Internal Medicine) 1979 Diplomate, Endocrinology and Metabolism (American Board of Internal Medicine) LICENSURE 1974-1979 Massachusetts 1974- North Carolina PROFESSIONAL SOCIETIES Association of American Physicians American Society of Biological Chemistry American Society of Clinical Investigation Endocrine Society American Federation of Clinical Research Southern Society of Clinical Investigation American College of Physicians North Carolina Medical Society Association of General Clinical Research Center Directors American Diabetes Association Growth Hormone Research Society Association of Program Directors in Endocrinology Pituitary Society IGF Society PROFESSIONAL SERVICE Consultancies: Monsanto Corporation, 11/10/82-1/1/02 Synergen, Inc., 12/12/86-12/31/90 Upstate Biotechnology, 1995-2004 Millipore, 2004-Present Genentech, Inc., 7/1/91-6/30/97 Nichols Institute Academic Associate, 5/1/90-12/11/99 Insmed Pharmaceuticals 4/1/00-3/31/2008 2 Celtrix Pharmaceuticals 1/1/92-4/15/01 Neurocrine, Inc 12/1/96-9/1/00 Academic Associate Quest Diagnostics 12/11/99-present Pharmacia 1/01/02- 3/31/03 AdHoc Consulting: Glaxo, Inc. Pfizer, Inc. Merck, Inc. Novartis, Inc. Chiron, Inc. Cephalon, Inc. Roche, Inc. Axys Pharmaceuticals Cor Therapeutics Bristol Myers Squibb Regeneron, Inc Ibsen, Inc Valero Pharmaceuticals Phyton Biotech Salix Pharmaceuticals Kowa Pharmaceuticals Scientific Advisory Boards: Neurocrine, 9/1/96-6/30/2000 Sensus Corp., 1995-7/31/01 Celtrix, Inc., 11/1/90-4/11/2000 Genetech Center for Clinical Research 6/1/98-present Lilly Hypocs Advisory Board 7/1/00-present Thera Technologies 7/1/01-12/31/2009 Pfizer Worldwide Endocrinology Board 11/1/03-present Insmed Inc, 1/1/2000-5/1/2008 Editorial Boards: Associate Editor Cecils Textbook of Medicine 23rd and 24th Editions, 2006, 2010 Editor, Endocrine Reviews, 2011-present Editor, Endocrinology, 1993-2002 Editorial Board, Journal of Biological Chemistry, 1999-2004 Associate Editor, Journal of Cellular Physiology, 1989-present Member, Editorial Board, Endocrinology, 1990-1992 Member, Editorial Board, Journal of Cellular Biochemistry, 1990- 2004 Member, Editorial Board, Molecular Endocrinology 2006- Reviewer ( > 3 yr.): Journal of Clinical Investigation Journal of Clinical Endocrinology Metabolism Endocrinology Grant Review Panels: Member, Cell Biology and Physiology Study Section (CBY-2) 1986-1990 Ad Hoc reviewer, NIH (Endocrinology Study Section, NHLBI, Division of Research Resources, and NIA) 1990-Present 3 Meeting Member, Program Committee of the Endocrine Society, 1989-1992 Organization: Vice Chairman, Gordon Conference on Peptide Growth Factors, 1990 Chairman, Gordon Conference on Peptide Growth Factors, 1992 Annual Meeting Steering Committee Endocrine Society 2006-2009 Member Program Committee Growth Hormone Research Society Meeting, Arhus Denmark, October 1996. Member, Program Planning Committee IGF Society Meeting, Tokyo Japan, September 1998 Member, Program Committee Growth Hormone Research Society Meeting, San Francisco, Ca, September 2000. Member Program Committee Growth Hormone Research Society Meeting, Canes Australia, September 2002 Co Chair Planning Committee for HYPOCCS Meeting Central and peripheral mechanisms of pituitary disease, Miami Florida, April 2003. Chair, Serono Symposium on IGF-I and Growth New Orleans La, June, 2004. Member, Program Committee Growth Hormone Research Society, Boston, Ma, September 2004. Member, Program Committee Pituitary Society Meeting, San Diego, Ca, June 2005. Member, Program Planning Committee Growth Hormone and IGF Society Meeting, Kobe Japan, September 2006. Member, Program Committee 29th Annual KIGS/KIMS Meeting, Berlin, Germany, September 2007. CoChair, Program Committee 10th HYPOCCs Meeting, Hypothalamic- Pituitary Disease and Obesity, Vancouver, Ca, April 2008. Member, Program Committee Growth Hormone and IGF Society Meeting, Genoa Italy, September 2008. Co Chair, Planning Committee, Isben Foundation Symposium IGF’s Local Repair and Survival and Factors throughout the Lifespan. Paris, France, December 2008. CoChair, Program Committee Consensus Conference on GH and IGF-I assays. Kenswick, Virginia, October 2009. Member, Program Committee Growth Hormone and IGF-I Research Society, New York, NY, September 2010. Chair, Program Committee 33rd Annual KIMS/Kigs Meeting, Rome Italy, May 2011. Officer: President, Pituitary Society 2003-2004 President Growth Hormone Research Society 2004-2006 RECENT GRANT SUPPORT Federal: 1981-2009 NIH 1-RO1 HL56850. Mechanisms by which IGF-I stimulates smooth muscle cells, PI. 1980-2014 NIH l RO1 AG0233l-26. Role of IGFBP-5 and integrins in controlling IGF- I actions, PI. 2004-2009 NIH PO1-AG24282. Changes in ROS systems and IGF-I roles in vascular aging, PI. 2006-2011 NIH-R41-HL084857-03. Development of a novel method of inhibiting atherosclerosis in diabetes, PI. 4 2011-2016 NIH R01-AR06114-01 Determination of the mechanism by which IGFBP- 2 stimulates bone remodeling Non Federal: 2008-2011 Juvenile Diabetes Research Foundation. Efficacy of an antiIAP antibody in blocking diabetic retinopathy. COMMITTEES University: 1984-1987 Member, Faculty Council 1985-1987 Member, Faculty-Trustee Committee 1990-2000 Member, Patent Committee 1992-1999 Member, Advisory Committee to the Program on Molecular Biology 2008-present Member, Jefferson Pilot Awards, Committee School of Medicine: 1979-present General Clinical Research Center Advisory Committee 198l-1987 Member, Critical Care Committee 1989 Biochemistry Chair Search Committee 1997 Pathology Chair Search Committee 1996 Biochemistry Chair Search Committee 1998-2002 Chairman, Gene Therapy Safety Subcommittee 2000-2004 Research Advisory Committee National: 1997-2000 Council Member - Endocrine Society 1998-2001 Council of Directors, Association of Program Directors in Endocrinology and Metabolism 1999-present Council, Pituitary Society International: 1995-present Member, Advisory Council Growth Hormone Research Society ADMINISTRATIVE Associate Director, Clinical Research Unit, 1979-2005 Director, Clinical Endocrine Teaching Services, 1981-1989 Division Chief, Division of Endocrinology and Metabolism, 1990-2007 Associate Chair for Research, Department of Medicine, 1997-2007 Director, Diabetes Center of Excellence, 2006-present TEACHING Lectures: Lectures to 2nd, 3rd, and 4th year medical students, 20 hours/year. Lectures to medical residents, 6 hours/year. Lab: Teaching of medical students (summer only) and postdoctoral fellows on a daily basis. 5 Clinical: Fourth year students in Endocrine Clinic, l hour/week. Fourth year students on Endocrine Service, 2 hours/day (1 month/year). CONTINUING EDUCATION Lecture in annual Internal Medicine Review Course, University of North Carolina at Chapel Hill. Area Health Education Centers (AHEC): 2-3 visits/year. Attending on Clinical Service: Endocrinology Consultation Service: 1 month/year.
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