Author Index

Page numbers in italics refer to bibliography

Aarsen,P.N. 501,506 Adkinson, N. F., J r., see Schellen• Ali,S.y', Lack,C.H. 301,307 Aas,K.A., Gardner,F.H. 415 berg,R.R. 347,372 Alkjaersig, N., Fletcher,A. P., Abdullahi, M .l, see Whittle, Adler,R.D., see Grant,R. 630, Sherry,S.l. 449,450 H.C. 244,265 652 Allen, D. l, see Reimers, H .1. Abe,K., Watanabe,N., Kuma• Adler,W.H., see Smith,R.T. 141,200 gai,N., Mouri,T., Seki,T., 322,330,341 Allen,F.H., Jr. 429, 450 Yoshinaga, K. 499, 506 Adolfs, M.J. P., see Bonta, I.L. Allen,F.H., lr., see Fu,S.M. Abell, C. W., Monahan,T.M. 554,562 428,454 306,307 Anggilrd,E. 409,410,415 Allen,J.C., Apicella, M.A. 257, Abercrombie, M. 114,129,206, Anggilrd, E., Larsson, c., 258,260 208,227 Samuelsson, B. 406, 408, 415 Allen,J.C., see Apicella,M.A Abercrombie, M., Ambrose, E. l Anggilrd, E., Samuelsson, B. 258,260 114,129 384,406,408,409,410,415 Allen,L.V. 622,649 Abercrombie, M., Heaysman, Anggilrd,E., see Nakano,1. AlIfrey,V.G., see Pogo,B.G.T. J.E.M. 114,129 412,419 323,340 Abercrombie, M., Heaysman, Agin,P.P., see Phillips,D.R. Alling,D.W., see Frank,M.M. J.E.M., Karthauser,H.M. 152,200 453 Allison,A.C. 98, 99, 212, 227, 114,129 Agudelo, C .A, see Schumacher, 276, 277, 288, 303, 304, 307, Ablondi,F.B., Hagen,J.J., H.R. 299,312 Allison,A.C., Davies, P. 76,99, Philips, M., Derenzo,E.C. Ahern,D.G., Dowing,D.T. 260, 260, 272, 275, 278, 288 449.450 141, 189,396,415 Abramovitch,A.S., Michaels, Allison,A. c., Davies, P., Petris, Ahkong, Q.F., Fisher,D., D.W., Mayer,M.M. 436, S., de 124, 129, 268, 288 Tampion, W., Lucy,lA. 450 Allison,A.C., Harington,J.c., Abramovitz,A.S., see Hammer, 115,129 Birbeck, M. 272, 277, 288 C.H. 433,434,455 Ahmed,K., see McLean,A.E.M. Allison,A.C., Houba, V., 47,65 Abramson,N., Alper,C.A., Hendrickse,R.G., Petris,S., Lachmann,P.J., Rosen,F.S., Ahtee,L., Michal,F. 145, 189 de, Edington,G.M., Adeniyi, Jandl,J.H. 445,450 Aiken, B. S., see Cochrane, C. G. A. 244,260 Abramson,N., see Alper,C.A. 241,261 Aliison,A.C., see Cardella,C.J. 442,445,450 Aikin,B.S., see Cochrane,C.G. 278,285,289 Ackerman,J., see Davies, P. 443,452 Allison,A.C., see Davies, P. 277, 289 Aken,W.G., van, Croote,T.M., 76,101,267,270,272-275,277, Ackermann,D. 13,19 Vreeken,1. 187,203 286,289,301,308 Adamik,R., see Baxter,J.H. Aledort, L. M., see Puszkin, E. Allison,A.C., see Finlay,C. 349,366 140,200 287.290 Adams,G.A, see Boyd,D.H.l Aledort,L.M., see Weiss,H.l Allison, A. c., see Page, R. C. 404,416 153,204 273-275,292 Adams, G . K. III, Lichtenstein, Alexander, B., Odake,K., Law- Allison,A.C., see Schorlemmer, L. M. 364,365 10r,D., Swangler,M. 163, H.U. 279,293 Adams, K. 365 189 Allison, F., Smith, M. R., Wood, Addison, W. 3 Alexander, B., see Leonardi, W.B. 111,124,128,129 Adeniyi,A, see AlIison,A.C. R.G. 153,197 Allison, F., Jr., Smith,M.R., 244,260 Alexander, P., see Evans, R. 77, Wood,W.B., Jr. 28, 49, 62 Adkinson,N.F., Jr., see 102 Allwood,G.G., see Asherson, Malveaux,F.J. 347, 370 Ali,S.Y., Evans,L. 301,307 G.L. 128,130 658 Author Index

Al-Mondhiry,H., Marcus,A.J., Andersen,H., see Nissen,H.M. Appert,H., see Satake,K. 499, Spaet,T.H. 179,189 408,420 518 Alper,C.A, Abramson,N., Andersen, H. T., Hammel, H. T., Arbuthnott,J. P., see Russell, Johnston,R. B., Jandl,J. H., Hardy,J.D. 630,649 R.J. 120, 133 Rosen,F.S. 442, 445, 450 Anderson,Al 299,307 Ardaillou,N., see Najean, Y. Alper,e.A, Balavitch,D. 437, Anderson, A. J., Brocklehurst, 165,199 450 W.E., Willis,A.L. 177. 189 Ardlie,N.G. 163,189 Alper, e. A, Boenisch, T., Anderson,F.L., Jubiz, W., Ardlie,N.G., Perry,D.W., Watson,L. 429,450 Kralios,A.e., Tsagaris,T.G. Packham, M.A., Mustard, Alper,e.A., Colten,H.R., Rosen, 412,415 M.A. 151, 189 F.S., Rabson,A.R., MacNab, Anderson,l F., see Rosenau, Arellano,M.R., Lawton,A.H., G.N., Gear,J.S.S. 430,441, M.l. 12,24 Dragstedt,e.A 15, 19 Arend, W. P., Mannik, M. 73, 442,450 Anderson, M. e., Schiller, W. R., 99 Alper, e. A., Propp, R. P., Gramatica,L. 499, 506 Arman,e.G., van 16,24, 465, Klemperer, M. R., Rosen, F .S. Anderson, M. S., see Schiller, 429,450 520 W.R. 499,518 Arman,e.G., van, Begany,AJ., Alper,e.A., Rosen,F.S. 447, Anderson, M. W., Eling, T. E. Miller,L.M., Pless,H.H. 450 414,415 480, 487, 502, 504, 520, 576, Alper,C.A., Rosen,F. S., Lach• Anderson,R.E., see Holley,T.R. 586 mann, P. J. 432,450 126,132 Arman,e.G. van, Carlson,R.P., Alper, e. A, see Abramson, N. Anderson, W., Jr., see Maling, Brown, W. R., Itkin, A. 185, 445,450 H. M. 480, 503, 515 203 Alper,C.A, see Davis,J.S.IV Anderson, W., Jr., see Webster, Arman,C.G. van, Carlson,R. P., 452 M.E. 490,491,502,503,521 Risley, E. A., Thomas, R. H., Alper, e. A., see Einstein, L. P. Ando, M., see Dannenberg,A. M Nuss, G. W. 490, 504, 520 428,429,453 87, 101 Arman,e.G. van, Nuss,G.W. Alper,e.A., see Hobart,K.l Andrade, S. 0., Rocha e Silva, M. 480, 487, 488, 503, 504, 520 434,455 16.19 Arman, e. G. van, Nuss,G.W., Alper,e.A., see Johnston,R.B., Andreis, M., Stastny, P., Ziff, M. Winter,C.A., Flataker,L. Jr. 432,456 259.260 480, 503, 504, 520, 602, 605, Alper, e. A., see Ziegler,J.B. Anigoni-Martelli, E., see Dieppe, 615 430,463 P.A. 261 Arman,C.G. van, see Kuehl, Alstead,S., see MacArthur,J.G. Ankier,S.1., Starr, M. S. 467, F.A. 554,565 527,531-533,565 506 Armour,S.R., see Sun,F.F. 409, Altman, L. e., Kirchner, H. Ansay,M., see Lenaers,A 219, 422 119, 129, 319, 337 229 Armstrong,D. 16, 19, 480, 506 Altman, L. e., Snyderman, R., Ansley, H., Ornstein,L. 70, 99 Armstrong,D., Dry,R.M.L., Oppenheim,].J., Mergen• Anslj:y,H., see Ornstein,L. 70, Keele,C.A., Markham,]. W. hagen,S.E. 332,337 105 480,506,591,593,608 Altman,L.e., see Snyderman,R. Antoniades, H. N., see Spangler, Armstrong, D., J epson,1. B., 118,134 A.S. 551,566 Keele, e. A. 471,506 Altman,L.e., see Wahl,S.M. Antonio,A., see Rocha e Silva, Armstrong, D., Jepson,J. B., 333,341 M. 17,23,484,504,505,517, Keele,e.A., Stewart,J. W. Altura, B. M. 575,585 582,586 16,19,480,498,506,591,593, Amberg,S., Loevenhart,A.S., Aoyaga,T., see Umezawa,H. 608 McClure, W.B. 529,532,560 300,312 Armstrong, D., Mills,G.L. Ambrose,E.J., see Abercrombie, Apicella,M.A., Allen,le. 258, 480,506 M. 114,129 260 Armstrong, D., see Jepson,J. B. Amer,M.S., Marquis,N.R. Apicella, M.A., see Allen,J.e. 16.22 156,189 257, 258,260 Armstrong, D., see Keele, C. A. Amos,H.E., Lachmann,P.J. Appel, W., see Werle,E. 470, 16,22,471,480,481,501,513, 317.337 521 588, 589, 591, 593-596, 612 Amundsen,E., Nustad,K. 473, Appelmans, F., see De Duve,e. Armstrong, D. A, Stewart, J. W. 506 482,508 484,493,502,506 Amundsen,E., Rugstad,H.E. Appenzeller,O., McAndrews, Armstrong, P. B., Lackie,J. M. 492,506 E.J. 557,560 113, 114, 130 Author Index 659

Arnold.J. 9. 10. 19. 51. 62 Astrakan, M., see Henriques, Austen,K.F., see Gigli,L 426- Arntzen. F. C .• Brisend, K. 555, O.B. 466,469,512 428, 437, 438,454 560 Aswanikumar,S., see Hook, Austen,K.F., see Goetzl,E.J. Arntzen,F.C., see Briseid,K. W.A. 348,351,369 125, 131,436,440,45~ 489,507 Aswanikumar,S., see Showell, Austen,K.F., see Goldman,J.N. Aronson,J.D. 315,337 H.1. 122, 134, 137 434,455 Aronson, M., see Rocha e Silva, Athens,]. W., see Rothstein,G. Austen, K.F., see Hunsicker, M. 13,23 95, 106 L.G. 446,447,456 Aronson,N.N., Jr., De Duve,C. A therton, A., Born, G: V. R. Austen,K.F., see Kaliner,M. 285,288 49, 51, 55, 62, 63, 112, 129, 306, 310. 348-350, 363, 369 Arroyave,C.M., Miiller-Eber• 130,584,585 Austen,K.F., see Kaplan,A.P. Atkins,E. 618,619,649 hard,H.J. 434,450 18,22,120,132,346,369,449, Arroyave,C.M., see Zimmerman Atkins,E., Bodel,P.T. 617, 456,470,472,490,513 T.S. 443,463 619,649 Austen,K.F., see Kay,A.B. Arthus,M. 12,19,231,234,260 Atkins, E., Bodel,P.T., Francis, 127.132.345.369 Arthus,M., Breton,M. 12, 19 L. 619,649 Artunkal, A. A., Marley, E. 628, Atkins,E., see Bodel,P.T. 619, Austen,K.F., see Kempf,R.A. 629,631,649 650 438.456 Artunkal,A.A., Marley, E., Atkins,E., see Dinarello,C.A. Austen,K.F., see Klemperer, Stephenson,]. D. 621, 629, 619,651 M.R. 428,456 631, 632, 647, 649 Atkinson,D.C. 527-529,532, Austen,K.F., see Koethe,S.M. Asboe-Hanson,G. 214, 227 560 437,456 Ascheim,E. 583,585 Atkinson, D. C., Boura,A. L. A., Austen,K.F., see Kondo,M. Ascheim, E., Zweifach,B. W. Hicks,R. 537, 539, 561 428,448,456 28.62 Atkinson,D.C., Hicks,R. 527, Austen,K.F., see Lewis,R.A. Aschoff, L. 97, 99 537-541,555,556,561 348, 350, 363, 370 Ash,A.S.F., Schild,H.O. 14. Atkinson,J.P., see Jaffe,C.J. Austen, K.F., see Nicholson,A. 19,353,366 449,456 429,438,458 Ash,]. F., see Wessells,N. K. Audet,A., Nantel, G., Proulx, P. Austen,K.F., see Orange,R.P. 140,204, 269,294 382,415 305,311,348,362,371 Ashenbrucker,H.E., see Roth• Augstein,J., Farmer,J. B., Lee, Austen,K.F., see Pisano,]. J. stein, G. 95, 106 T. B., Sheard, P., Tattersall, 465,472,516 Asherson,G.L., Allwood,G.G., M.L. 363,366 Austen, K.F., see Rosenfeld,S.L Mayhew,B. 128, 130 Austen, see Goetzl, 137 Asherson, G. L., see Zembala, M. Austen,K. F. 352, 353, 366 427,460 250, 251, 266 Austen,K.F., Orange,R.P. Austen,K.F., see Ruddy,S. Ashton,F.E., Jamieson,J.c.. 345, 348, 364, 366 27!, 293, 428, 430, 439, 441, Friesen,A.D. 545, 560 Austen, K.F., Sheffer,A. L. 446,447,460,461 Ashworth, L.A. E., Eckersley, 439,450 Austen,K.F., see Sargent,A. U B.J., Ford,W.H. 332,337 Austen,K.F., see Bach,S. 427, 438.461 Ashworth,L.A.E., see Ford, 450 Austen,K.F., see Schreiber,A. D W. H. 320, 338 Austen,K.F., see Becker,E.L. 436,449,461 Askenase, P. W. 314,337,359, 183, 190 Austen, K.F., see Sheffer,A.L. 366 Austen, K.F., see Burge,J.J. 439,449,461 Askenase, P. W., see Avella,]. 448, 449, 451 Austen,K.F., see Soter,N.A. 365,366 Austen,K.F., see Caldwell,]. 449.461 Askenase, P., see DeBernardo, 438,451 Austen,K.F., see Spragg,]. R. M. 359,367 Austen,K.F., see Caldwell,J.R. 467,519 Askenase, P. W., see Gershon, 438, 439, 451 Austen, K. F., see Stechschulte, R. K. 345, 356, 360,368 Austen.K.F., see Daha,M.R. 182,202,362,373 Askenase, P. W., see Schwartz,A. 430,431,433,447,452 Austen, K. F., see Stroud,R.M. 365,372 Austen,K.F., see Drazen,].M. 428.448,462 Asmden,A., see Yoshida,T. 364,367 Austen,K.F.,see Valone.F.H. 320,342 Austen,K.F., see Fearon,D.T. 173,176,203 Assimeh,S.H., Bing,D.H., 429-433,436,448,453 Austen,K.F., see Wasserman, Painter,R.H. 426,450 Austen,K.F., see Fostiropoulos, S. L 286, 293, 302, 312, 362, Aster,R.H. 165,189 G. 446,453 373 660 Author Index

Austen, K.F., see Weiler,J .M. Baile,C.A., see Martin,F.H. Bancroft,F.e., see Rommel, 430,448,449,463 626,653 F.A. 434, 460 Austen,W.G., see Orange,R.P. Bailey,A.J., Robins,S.P. 217, Bandmann, U., Rydgren,L., 305,311 227 Norberg,B. 124,130 Auteri,A., see Perri,T. di 448, Bailey,A.J., see Hodge,A.J. Banerjee,S., Glynn,L.E. 210, 459 218,228 227 Avella,]., Madsen'].E., Binder, Bainton,D.E., see Bodel,P.T. Bangham,A.D. 49, 63, 110, H.J., Askenase,P.W. 365, 72,100 112,130 366 Bainton, D.F. 297,307 Barbanti-Brodano, G., Fiume, L. Axelrod,]., see Saavadra,J.M. Bainton,D.F., Farquhar,M. 267,288 325,372 297,307 Barber,A.J., see Jamieson,G.A. Axelrod,]., see Snyder,S.H. Bainton,D.F., Farquhar,M.G. 110,132 352,373 297,307 Barber,M., see Delaunay,A. Axline,S.G., Cohn,Z.A. 272, Bainton,D.F., UlIyot,J .L., 118,131 288 Farquhar, M.G. 297,307 Barger,G., Dale,H.H. 13. 19 Axline,S.G., Reaven,E.P. 269, Bainton,D.F., see Jensen, M.S. Barkas, T., Scott, G. K., 278.288 298,310 Fothergill,J .E. 426,450 Axline,S.G., see Pesanti,E.L. Bainton,D.F., see Nichols,B.A. Barker, J . L., see Levitan, H. 304,311 72,105 605,612 Axline,S.G., see Reaven,E.P. Baird,J.A., Hales,J.R.S., Lang, Barland,P., NovikotT,A.B., 114,124,133 W.J. 623, 626, 627, 629, 649 Hameran,D. 284,288 Barland, P., Novikoff,A.B., Ayoub,E.M., McCarty,M. Baird,J .A., see Hales,] .R.S. Hammerman,D. 299,307 273,288 625,629,652 Barnhart,M.I., Quintana,C., Baker,B.R., Cory,M. 448,450 Babilli,S., see Vogt, W. 380, Lenon,H.L., Bluhm,G.B., Baker,P .• see McLeod,B. 447, 422 Riddle,J .M. 299,307 457 Bach,F.H., see Janis,M. 319, Barnhardt,M.I., Walsh,R.T., Balavitch,D., see Alper,C.A. 322,339 Robinson,J.A. 143,189 437,450 Bach,M.K., Brashler,J.R. Barnhart,M.J., see Purcell, 363,366 Bald,M., see Breddin,K. 147, G.M. 301,311 Bach,S., Ruddy,S., Maclaren, 191 Barott,H.G., Pringle,E.M. A.J., Austen,K.F. 427,450 Baldessarini,R.J., see Snyder, 627,649 Back,N., Munson,A.E., S.H. 352, 373 Barratt,M.E.J. 285,288 Guth,P.S. 494,506 Baldini,M., see Terada,H. 186, Barratt,M.E.J., see Fell,H.B. Badcock,J.K., see Ford-Hut• 203 284,290 chinson,A.W. 547,563 Balestieri,B., see Capasso,F. Barratt,M.E.J., see Poole, Badonnel,M.C., see Gabbiani, 576,485 A.R. 284,285,292 G. 38,41,64 Balfour,B.H., see Kelly,R.H. Barrett,A.J. 285,288,299,301. Baenziger,N.L., see Brodie, 319,339 302,307 G.N. 139,153,191 Balk,S.D., see Whitfield,J .F. Barrett,A.J., Dingle, LT. 297, Baenziger, N .L., see Majerus, 322,341 307 P.Q. 142,197 Ball,J.H., see Broadus,A.E. Barrett,A.J., Starkey,P.M. Bagdasarian,R.A., Talamo, 305,308 300,307 R.e., Colman,R.W. 472, Ballantyne,D.L., Jr., Coburn, Barrett,A.J., see Dingle,J.T. 506 R.J., Hawthorne,G.A., 283, 285, 286, 290, 300, 308 Bagdasarian, R. A., see Lahiri, B. Nathan,P. 188,189 Barrett,A.J., see Morrison,R.1. 469,470,514 Ballow,M., Yang,S.Y., Day, G.179,198,301,311 Baggiolini, M., Hirsch, J . G., N.K. 442,450 Barrett,A.J., see Weston,P.D. De Duve,C. 268,288,296, Ballow, M., see Einstein, L. P. 300,313 307 429,453 Bartels,J., Kunze, H., Vogt,W, Baggiolini, M., see Bretz, U. Balme, H. W., see Dieppe, P.A. Wille,G. 380,415 268,289,296,308 258, 259, 261 Bartholini,G., see Pletscher,A. Baggiolini, M., see Dewald, B. Balner,H. 77,99 141,200 268,270,290 Balow,J .E., Rosenthal,A.S. Bartosch,R., Feldberg, W., Baile,C.A., Simpson,C.W., 287,288,333,337 Nagel,E. 13,19 Bean, S. M., Jacobs, H.J. Bamzai,A.K., Kretschmer,R.R, Barve,J.A., see Downing,D.T. 626,627,649 GototT,S.P. 351,366 414,417 Author Index 661

Basel,J.F., see Wilkinson,P.C. Becker,E.L. 426,448,450 Behin,R .. see Mauel,J. 76, 105 176,205 Becker,E.L., Austen,K.F. Behnke,O. 138, 140,190 Bass,N.H., see Spector,A.A. 183,190 Behrends, C., see McLeod, B. 182,202 Becker,E.L., Davis,A.T., 447,457 Basten,A., Mitchell,J. 77,99 Estensen,R.D., Quie,P.G. Beiler, J . M., see Goldstein, S. Batho,H.F.,seeWhitelaw,D.M. 124, 130 528, 529, 531, 534, 538, 539, 108 Becker,E.L., Henson,P.M. 540,555,563 Baudry,M., Martres,M.-P., 272,288,348,349,366 Beiler,J.M., see Hitchens,J.T. Schwartz, J.c. 354, 355, 366 Becker,E.L., Showell,H.J. 527, 531, 532, 534, 541, 564 Bauer,H., see Matthew,T.H. 119,124,130 BeIeslin,D.B., see Varagic,V.M. 188,198 Becker,E.L., Showell,H.J., 636, 643,655 Baugh,R., Brown,J., Sargeant, Henson,P.M., Hsu,L.S. Bell,E.B., see Shand,F.L. R., Hougie,C. 163,189 119,130,271,288 77, 106 Baum,J., see Leddy,J .P. 434, Becker,E.L., see Feinman,L. Bell,F.M., see Whitelaw,D.M. 457 449,453 108 Baum,J., see Rosenfeld,S.1. Becker,E.L., see Naccache,H.J. Bell,W.R., Miller,R.E., Levin, 433,445,460 124,133 R.J. 246,260 Baumgarten,A., Melrose, Becker,E.L., see Rivkin,1. 125, Beller,F.K., see Nagayama,M. G.J.H., Vagg,W.J. 477,506 133 184,199 Baumgartner,H.R. 142, 143, Becker,E.L., see Schiifmann, E Benacerraf, B., Gell, P. G .H. 147, 151, 165, 173, 189, 190 120,134 238,260 Baumgartner,H.R., Born, Becker,E.L., see Showell,H.J. Benacerraf, B., Levine, B. B. G.V.R. 151,190 124, 134, 137 238,260 Baumgartner,H.R., Muggli,R., Becker,E.L., see Ward,P.A. Benacerraf, B., Paul, W .E., Tschopp,T.B., Turitto,U.T. 124,135 Green, I. 238, 260 143, 190 Beckerdite,S., see Patriarca,P. Benaceraif, B., see Berken, B. Baumgartner,H.R., see Muggli, 382,420 277,288 R. 159, 198 Beckman,B., see Flores,J. 305, Benacerraf, B., see Bloch, K. J. Baumgartner,H.R., see 308 235,240,260 Tschopp,T.B. 151, 166,203 Bedwani,J.R., Marley,P.B. Benditt,E.P., see Ross,R. 220, Baumgartner,H.R., see Weiss, 409,415 229 H.J. 165, 166, 169,204 Beecher,H.K. 588, 601, 606, Benditt,E. P., see Rowley,D.A. Bauminger,S., see Melmon, 609 15,24 K.L. 356,358,370 Beecher,H.K., Keats,A.S., Ben-Efraim,S., Cinader,B. Bauscher,J .A.C., see Smith, Mosteller,F., Lasagna,L. 443,450 R.T. 322,330,341 601,609 Ben-Efraim,S., see Schlossman, Baxter,J .H., Adamik,R. 349, Beecher,H.K., see Smith,G.M. S.F. 238,264 366 596,615 Bayliss,J., see Rixon,R.H. Beelen,R.H.J., Broekhuis• Benitz,K.F., Hall,L.M. 275, 497,517 Fluitsma,D.M., Korn,C., 288 Benjamin,F.B. 593,609 Bazin,S., Delanay,A. 300, 307 Hoefsmit,E.C.M. 73,100 Bazin, S., Nicoletis, C., Been,M., see Winder,C.V. Benjamin,F.B., Helvey,W.M. Delaunay,A. 223, 224, 227 531,567 593,609 Beach,V.L., see Di Pasquale,G. Been,M.A., see Winder,C.V. Benjamini,E., see Spitier,L. 531,537,538,562 582,587 332,341 Bean,S.M., see Baile,C.A. Beerthuis,R.K., see Dorp,D.A., Bennelli,G., see Della Bella,D. 626,627,649 van 384,417 590,599,610 Beaven,M.A. 353,366 Beerthuis,R.K., see Nugteren, Bennet,A., Posner,]. 632, 650 Beaven,M.A., see Kaplan,A.P. D.H. 386,387,393,395,420 Bennet,A., see Swinson,D.R. 352,361,369 Beeson, P .B. 618,649 179,202 Beaver, W.T. 602,608 Beeson,P.B., see Bennett,l.L. Bennett,A. 413,416 Beck,N.P., see Park,B.H. 305, 618,650 Bennett,A., Friedman,C.A., 311 Begany,A.J., see Arman,C.G. Vane,J.R. 393,416 Becker,C.G., Murphy,G.E. van 480, 487, 502, 504, 520, Bennett,A., see Eakins,K.E. 36,38,63 576,586 175,192 Becker,E., see Glovsky,M.M. Begent,N.A., Born,G.V.R. Bennett, B., Bloom,B.R. 319, 448,454 584,585 326,337 662 Author Index

Bennett,B., see Bloom,B.R. Berlin,R.D., see Tsan,M.F. Bhatnagar,R.S., Prockop,D.J. 316, 317, 319, 321, 324, 331, 115,134 216,227 337 Berlin,R.D., see Ukena, T .E. Bhisey,A.N., Freed,J.J. 124, Bennett,E.N., see Kessler,E. 115,135,140,203 130 412,418 Berman,I.J.,see Plaut,M. 358, Bhoola, K. D., Schachter, M. Bennett,I.L., Beeson, P. B. 371 477,506 618,650 Berman,L. 115,130 Bianco,C. 73,100 Bennett,J., Glavenovich,J., Bern,M.M., see Bing,D.H. Bianco, C., Griffin, F .M., Liskay,R., Wulff,D.L., 427,451 Silverstein,S.e. 73, 100, Cronan,J.E., Jr. 382,416 Bernard,A. 499,506 442,451 Bennett,J.e., see Hurst,M.M. Bernard,C. 7,10,11,19 Bianco, C., N ussenzweig, V. 426,456 Bernard,J., see Inceman,S. 73, 100 Bennett,J.S., see Colman,R.W. 165,196 Bianco, e., see Griffin, F. M. 168, 172,191 Bernard,J., see Najean, Y. 165, 73,103,442,455 Bennet,J .L., Jr., Petersdorf, 199 Bianco, P. L.D., see Sicuteri,F. R.e., Jr., Keene, W .R. Bernardi,D., see Garattini,S. 467,501,519 620,621,650 527,528,563 Bielefeld,D.R., see Senior,R.M. Bennett,J.W., see Hales,J.R.S. Bernardi,D., see Jori,A. 527, 280,293 625,629,652 531,534,558,564 Bienenstock,J., see Dolovich,J. Bennett, V., see Cuatrecasas, P. Berneis,K.H., see Pletscher,A. 345,367 346,367 141,200 Bier,O.G., RochaeSilva,M. Bennich,H., see Ishizaka,T. Berridge,M.J. 360,366 15, 16, 19 214,228 Berry,H., Giroud,J.P., Bier,O.G., see Rochae Silva,M. Bensch, K.G., Malawista, S .E. Willoughby,D.A. 253,255, 13,15,24 303,304,307 260 Bierman,H.R. 95,100 Bensch,K.G., see Malawista, Bertelli, A. 482,506 Bieron,K., see Gryglewski,R.J. S.E. 269,292 Bert.het,J., see De Duve,C. 168, 172, 194 Bentley,C., Bitter-Suermann,D, 295,308 Bierwagen, M.E., see Fleming, Hadding, U., Brade, V. 429, Berthrong,M., see Cluff,L.E. J .S. 185, 193 451 185,191 Bigazzi,P.E., see Yoshida,T. Benveniste,J. 348,366 Bessis,M. 119,130 320,342 Biggs,R. 162,190 Beraldo,W.T. 465,470,494, Bessis,M., Burte,B. 119,130 Bignold,L.P., Lykke,A.W.J. 506 Bessis,M., see Keller,H.U. 478,506 Beraldo, W .T., Dias da Silva, 126,132 W. 14,19,573,585 Billimoria,F.J., see Ford• Best,C.H., Dale,H.H., Dudd• Hutchinson,A.W. 547,563 Beraldo, W.T., see Henriques, ley,H.W., Thorpe,W.V. Billingham,M.E.J., Davies, O.B. 465,512 13,19 G.E. 548,561 Beraldo,W.T., see Rochae Bevegard,S., Oro,L. 598, 609 Silva,M. 16,23, 464, 465, Billingham,M.E.J., Gordon, Beveridge,G.C., see Kuehl,FA A.H. 538, 545, 548, 561 471,517 554,565 Berde, B., see S tiirmer, E. Billingham,M.E.J., Gordon, Bhabani,A.R., see Onabanjo, A.H., Robinson,B.V. 547, 464,519 A.O. 493,516 Berg,H.C., Brown,D.A. 117, 548,561 Bhalla,T.N., Sinha,J.N., Billingham,M.E.J., Robinson, 130 Tangri,K.K., Bhargava, Berger,N., see John,S. 296, B. V. 539, 542, 545, 561 K.P. 469,506 310 Billingham,M.E.J., Robinson, Bergstrom,S., Danielsson,H., Bhargava,A. K., see Tangri, B.V., Robson,J.B. 533, K.K. 621,655 Klenberg, D., Samuelsson, B. 537, 538, 540, 542, 544, 545, 384,416 Bhargava,K.P., see Bhalla, 548,561 Bergstrom,S., Danielsson,H., T .N. 469,506 Billingham,M.E.J., Robinson, Samuelsson,B. 384,416 Bhargava,K.P., see Tangri, B.V., Robson,J.M. 533,537, Berken, B., Benaceraff, B. K.K. 621,655 540,542,545,548,561 277,288 Bhargava,N., see Bonta,l.L. Billingham,M.E.J., see Gaugas, Berlin,R.D.,Oliver,J.M., 532, 537, 540, 542,561 J.M. 529,545,563 Ukena,T.E., Yin,H.H. Bhargava,N., see Vincent,J .E. Bills,T.K., Silver,M.J. 159, 115,130 551,567 178,190 Author Index 663

Bills,T.K., Smith,I.B., Silver, Blackwell,G.I., Flower,R.J., Boackle,R.J., Pruitt,K.M., K.I. 159,190 Vane,1 .R. 396,397,409,416 Mestecky,1. 451 Binder,H.I., see Avella,1. 365, Blackwell,G.I., see Flower,R.J. Boas, N .F. 216,227 366 381,411,417 Boas,N.F., Ludwig,A.W. 216, Bing,D.H. 448,451 Bladen,H.A., see Lazarus,G.S. 227 Bing,D.H., Spurlock,S.E., 302,310 Bochert, G., see Riihl,H. 119, Bern,M.M. 427,451 Blanden,R.V. 251,260 133 Bing,D.H., see Assimeh,S.H. Blanden,R.V., Hapel,A.J., Bochner,B.S., see Thomas,L.L. 426,450 Doherty, P.c., Zinkernagel, 365,373 Bing,D.H., see Sledge,C. 448, R.M. 76,100 Bodel,P., Dillard,G.M., 461 Blanden, R. V., see Mackaness, Kaplan,S.S., Malawista, Biozzi,G., Mene,G., Ovary,Z. G.B. 325,339 S.E. 551,561 16, 19 Blatt,I.M., Seltzer,H.S., Bodel,P.T., Nichols,B.A., Birbeck,M., see Aliison,A.C. Rubin,P., Furstenberg,A.C., Bainton,D.E. 72,100 272,277,288 Maxwell,1.H., Schull,W.J. Bodel,P.T., Wechsler,A., At• Biro,C.E., see Nelson,R.A. 99,100 kins,E. 619,650 438,458 Blazkovec,A.A., see Hulliger, P. Bodel,P.T., see Atkins,E. Bischoff,R., see Ishikawa,H. L. 251,262 617,619,649 269,291 Blengio,J .R., see Katona,G. Bodel,P.T., see Dinarello,C.A. Bishop,C.R., see Rothstein,G. 18,22 619,651 Bogden,A.E., see Sarcione,E.J. 95,106 Blennemann,G., see Haber• 545,547,566 Bishop,E.A., see Margolis,l. mann,E. 465, 466, 469, 512 Boenisch, T., see Alper,C.A. 466,471,515 Blersch,H.V. 1,4 429,450 Bishop, G .H., Landau, W. Bligh,1., Milton,A.S. 625, Boerhaave,H. 2 591,592,609 629,650 Boetcher, D .A., Leonard, E. J. Bishop, G. H., see Landau, W. Bloch,K.J. 347,366 345,348,359,366 594,606,612 Bloch,K.J., Kourilsky,F.M., Boggs,D.R., Chervenick, P.A., Bitter-Suermann,D., see Bent• Ovary,Z., Benacerraf,B. Marsh, I .c., Cartwrigh t, G . E., ley,C. 429,451 235, 240,260 Wintrobe,M.M. 95,100 Bitter-Suermann,D., see Brade, Bloch, K.J., see Einstein, L. P. Bohm,G.M., see Garcia-Leme, V. 429,451 428,453 J. 552,563 Bitter-Suermann,D., see Burger, Bloch,K.J., see Fostiro• Bohman,S .0., Larsson,C.A. R. 279,289,432,447,451 poulos,G. 446,453 382,416 Bitter-Suermann,D., see Blondin,1., see Janoff,A. 286, Bohn,E., see Kunze,H. 411, Nicholson,A. 431, 433, 458 291 419 Bjorkhem,1., see Hamberg, M. Bloom,B.R. 317,337 Bohr,D.F., see Strong,C.G. 406,418 Bloom,B.R., Bennett,B. 316, 604,605,615 Black,I.W. 352, 354, 355,366 317,319, 321, 324, 331, 337 Boissonnas,R.A. 20 Black,I.W., Duncan, W.A.M., Bloom, B.R., Glade, P. R. 320, Boissonas,R.A., Guttmann,S., Durant,C.I., Ganellin,C.R., 337 Jaquenoud,P.A. 464,506 Parsons,E.M. 354,366 Bloom,B.R .. see Bennett,B. Boissonnas,R.A., Guttmann,S., Jaquenoud, P .A., Konzell, H., Black,I.W., Duncan,W.A.M., 319,326,337 Stiirmer,E. 16,20,474,507 Durant,G.I:, Ganellin,C.R., Bloom,B.R., see Henney,C.S. Boissonas,R.A., Guttmann,S., Parsons,M.E. 14,19,333, 358,368 Jaquenoud, P.A., Pless,1., 337 Bloom,B.R., see Maillard,J. Sandrin,E. 464,507 Black,J.W., see Brimblecombe, 319,339 Boissonnas,R.A., see Pless,1. R.W. 355,366 Bloom, F., see Siggins,G. 607, 464,516 Blackwell,G.J., Duncombe, 614 Bokisch,V.A., Dierich,M.P., Bloomberg,N., see Zucker• W.G., Flower,R.J., Parsons, Miiller-Eberhard,H.J. M.F., Vane,J .R. 159, 178, Franklin,D. 140,205 428,451 190,411,416 Bluhm,G.B., see Barnhart,M.l. Bokisch, V.A., Miiller• Blackwell,G.J., Flower, R.I. 299,307 Eberhard,H.I. 436,440, 381,409,414,415,416 Blum, L., see Pillemer, L. 235, 451 Blackwell,G .1., Flower,R.J., 264,428,432,459 Bokisch, V.A., Miiller-Eber• Parsons,M.F., Vane,I.R. Blusse,A., Furth,R. van 83, hard,H.J., Cochrane,C.G. 400,416 100 234,260 664 Author Index

Bokisch,V.A., see Budzko,D.B. Bonta,I.L., see Noordhoek,J. Boros,D.L., see Warren,K.S. 234,260 527, 528, 530, 532, 534, 536, 87,107 Bokisch, V.A., see Hartmann, 538, 539, 542, 543, 546, 565 Boros-Farkas, M., IlIei-Don• K.U. 442,455 Bonta,1.L., see Parnham, M.J. hoffer,A. 621,650 Bokisch, V .A., see Wuepper, 554,565 Borrero,L.M., see Pappen• K.D. 234,265 Bonta,1.L., see Vincent,J.E. heimer,J .R. 33,66 Bolam,J. P., Elliot, P.N.C., 159, 168, 172, 203, 551, 567 Borsos, T., Rapp,H.J. 425, Ford-Hutchinson,A.W., Boot,J .R., Dawson, W., Kit• 451 Smith,M.J.H. 488,507, chen,E.A. 175,190 Borsos,T., Rapp,H.J., Colten, 547,561 Booyse,F., Kisieleski,D.I., H.R. 427,451 Bolam,J. P., Ford-Hutchinson, Seeler,R. 167,190 Borsos,T., Rapp,H.J., Mayer, A.W., Elliott,P.N.C., Smith, Booyse, F. M., Rafelson, M. E. M. M. 428, 436,451 M.J.H. 547,561 139, 142, 190 Borsos, T., see Colten,H.R. Bolam,J.P., see Elliott;P.N. Booyse, F. M., see Legrande, Y. 427,452 547,562 272,292 Borsos,T., see Wyatt,H.V. Bolam,J .P., see Ford-Hutchin• Booyse, M. E., see Legrand, Y. J. 428,463 son,A.W. 547,563 179,197 Borysenko,J.Z., see Ryan,G.B. Bolam,J.P., see Smith,M.J.H. Borchgrevink,C.F., see 115,134 547,566 J0rgensen,L. 165, 196 Bosmann,H.B. 140,190 Boldingh,J. 177,190 Bordet,J. 13,20 Bossen,E.H., see IIgen,C.L. Bombardieri,S., see Gocke,DJ. Boreham, P. F. L. 492, 507 427,456 242,262 Borel,J.F. 119, 126, 130 Boughton,B., see Willoughby, Bommer,S. 593,609 Borel,J.F., Keller,H. U., D.A. 315,342,571,587 Bonardi,G., see Coppi,G. 181, Sorkin,E. 119,130 Boulton-Jones,J. M., see Peters, 191 Borel,1.F., see Keller,H.U. D.K. 447,459 Bounameaux, Y. 139, 190 Bonner,M.J., see John,S. 296, 119.132 Boura,A.L.A., see Atkinson, 310 Borges,D.R., Gordon,A.H. D.C. 537,539,561 Bonney,R.J., see Davies, P. 468,507 Bourne,H.R. 553,562 101 Borges,D.R., Prado,J.L., Bourne,H.R., Lehrer,R.I., BonnycastJe,D.D., Cook,L., Guimaraes,J.A. 466,507 Lichtenstein, L. M., Weiss- Ipsen,J. 607,609 Borges,D.R., see Guimares, mann,G., Zurier,R. B. 305, Bonta,I.L. 523, 527, 529, 530, J .A. 466,511 Borison,H.L., see Sheth, U.K. 307 534,550,561 Bourne,H.R., Lichtenstein, 620,655 Bonta, 1. L., Bhargava, N., L.M., Henney,C.S., Melmon, DeVos,CJ. 532,537,540, Borisy,G.G., see Weisenberg, K.L., Weinstein, Y., Shearer, 542,561 R.C. 303,304,312 G. M. 345, 350,366 Born,G.V.R. 138, 143, 144, Bonta,1.L., Chrispijn,H., Bourne,H.R., Melmon,K.L., Noordhoek,J., Vincent,J.E. 145,147, 151, 190 Lichtenstein,L.M. 553, 562 Born,G.V.R., Cross,M.J. 543,561 Bourne,H.R., see Henney,C.S. 584,585 Bonta,1.L., De Vos,c.J. 490, 305,306,309 Born,G.V.R., Gillson,R.E. 507, 528, 529, 530, 535, 537, Bourne,H., see Lichtenstein, 538, 540, 541, 545, 546, 550, 141,190 L. M. 350,370 Born,G.V.R., see Atherton,A. 551,561 Bourne,H.R., see Melmon,K.L. Bonta,I.L., De Vos,C.J., 49,51,55,62,63,112,129,130, 356,358,359,370 Delver,A. 551,561 584,585 Bourne,H.R., see Mozes,E. Bonta,1.L., Noordhoek,J. Born,G.V.R., see Baumgartner, 358,371 529, 530, 532, 534, 537, 538, H.R. 151,190 Bourne,H.R., see Weinstein, Y 540,542,547,548,561 Born,G.V.R., see Begent,N.A. 359,373 Bonta,1.L., Parnham,M.J., 584,585 Bovaird,L., see Maudsley,D. V Adolfs,M.J. P. 554,562 Bornstein, P. 220, 221, 227 365,370 Bonta,1.L., Parnham,M.J., Bornstein,P., Ehrlich,H.P. Bovet,D., Staub,A.M. 14, 20 Van VIiet,L., Vincent,J.E. 220,227 Bovet,D., Waithert,F. 14,20 554,562 Bornstein,P., Piez,K.A. 218, Bowman,B., see Glenn,E.M. Bonta,1.L., Vargaftig,B.B. 227 181, 193 551,562 Bornstein,P., see Ehrlich,H.P. Bowman,B.J., see Glenn,M. E Bonta, 1. L., Vargaftig, B. B., 220,228 548,559,563 De Vos,c.J., Grijsen,H. Bornstein, P., see Kang, A. H. Boyd's Textbook of Pathology 551,562 217,228 3,4 Author Index 665

Boyd,D.H.J., Adams,G.A. Braude,A.I., Carey,F.J., Brimblecombe,R.W., Duncan, 404,416 Zalesky, M. 185, 191. 621, W.A.M., Durant,G.J., Boyden,S. 329,337 650 Ganellin, C .R., Parsons, E. M., Boyden,S .Y. 116, 118, 120, Braun, e., see Guzman,F. 16, Black,J .W. 355,366 130 17,21,481,501,511,589,590, Brine, K.L., see Moses,l.M. Boyden,S .Y., see Nelson, D.S. 591, 593, 594, 596, 597, 599, 112,133 319,340 602, 603, 605, 611 Briseid, K., Arntzen, F .C., Boyer,J.T., Gall,E.P., Nor• Braun, e., see Lim,R.K.S. 16, Dyrud,O.K. 489,507 man, M .E., Nilsson, U.R. 22, 481, 501, 514, 589, 590, Brisend, K., see Arntzen,F.C. 434,451 592, 600, 603, 612 555,560 Boyer,J.T., see Pensky,J. 459 Braun-Falco,O. 98,100 Britton, M.e., Schur, P.H. Boyer,J.T., see Westberg,N.G. Braunstein, H., Freiman,D.G., 446,451 447,463 Thomas,W., Gall,E.A. 99, Broadus,A.E., Hardman,l.G., Boyle-Kay,M.M., Fudenberg, 100 Kaminsky,N.1., Ball,l.H .. H.H. 140, 144, 145, 190 Braunsteiner, H., Schmalzl.F. Sutherland, E. W., Liddle, Boylston,A., see Feldman, M. 70,100 G.W. 305,308 76, 102 Bray,M.A., Dumonde,D.e., Brocklehurst, W .E. 362, 364, Bozicevich,J., see Waalkes,T.P. Hanson,l.M., Morley,J., 366 183,204 Wolstencroft,R.A., Smart, Brocklehurst, W .E., Lahiri,S.C. Brade, Y., Dieminger, L., 1. Y. 320, 325, 327, 332, 333, 494, 495, 507 Schmidt, G., Yogt, W. 438, 337 Brocklehurst, W .E., Zeitlin, U. 451 Bray, M.A., Gordon,D. 323, 468,507 Brade, Y., Hall,R.E., Colten, 335,337 Brocklehurst. W.E., see H .R. 429,451 Bray,M.A., Gordon,D., Anderson.A.J. 177.189 Brade, Y., Lee, G .D., Nichol• Morley,]. 333,334,336,337, Brocklehurst, W.E., see Willis, son,A., Shin,H.S., Mayer, 554.562 A.L. 153,168,170,175,177, M.M. 431.451 Bray,M.A., see Gordon,D. 205,627,631,645,646,655 Brade, v., Nicholson, A., 324.334,338 Brockway, W.J., Castellino, Bitter-Suermann, D., Had• Bray,M.A., see Morley,l. F.M. 449,451 ding, U. 429,451 336, 340, 554, 559, 560, 565 Brodie,B.B. 548, 558,562 Brade, Y., Nicholson,A., Lee, Breckenridge,B.McL., Lisk, Brodie, G .N., Baenziger, N . L., G.D., Mayer,M.M. 235, R.D. 636,650 Chase,L.R., Majurus,P.W. 260,429,451 139, 153, 191 Breckenridge,R.T., see Graff, Brade, Y., see Bentley,C. 429, K.S. 443.455 Brodie,G.N., see Majerus,P.Q. 451 142,197 Brade, Y., see Burger,R. 279, Breckenridge,R.T., see Keller• meyer,R.W. 490, 491, 499, Brody,M.J., see Powell,J.R. 289 355,372 513 Brade, Y., see Nicholson,A. Broekhuis-Fluitsma, D .M., see Breddin, K., Krzywanek,1. K., 430-433,458 Beelen,R.H.J. 73,100 Bradley, M. D., see Wessels, Bald,M., Kutschera,1. 147, Bronk,D.W., see Gammon, N .K. 269,294 191 Brederoo,P., see Deams,W.T. G.D. 531,563 Bradley,M.O., see Wessells, Bronson,S .D., see Needleman, N.K. 140, 204 72,101 P. 154,157,199 Bradley, T .R .. Metcalf, D. 93, Brem,J., see Kohn,l.L. 242, Brooks, B. 593,609 100 263 Brooks,G.F., see Peterson, Brady,R.O., King,F.M. 98, Brenner, W .E., see Hendricks, B.H. 434,459 100 C.H. 625,652 Braga, P . C., see Ferri, S. 608, Breslow,]., Rothman,P., Brotanek, Y., see Hendricks, 610 Colten, H .R. 434. 451 C .H. 625,652 Brai, M., see Goldstein, I .M. Breton,M., see Arthus,M. 12. Broun,G.O., Jr., Broun,G.O., 271,290 19 Snr. 187,191 Brain,J.D., see Godleski,J.G. Bretz, U., Baggiolini, M. 268, Broun, G .0., Snr., see Broun, n, 103 289,296.308 G.O.,lr. 187,191 Brand,H., see Weiss,H.J. 156, Bretz, U., see Dewald, B. 268, Brown, D., see McCall,C.E. 166-171,204 270,290 441,457 Brandes, D. 297, 308 Brier,A.M., Snyderman,R .. Brown,D.A., see Berg,H.e. Brashler,l.R., see Bach,M.K. Mergenhagen, S .E .. N otkins, 117.130 363,366 A.L. 119,130 Brown,D.L. 236,260 666 Author Index

Brown, D. L., Lachmann, P. J. Buck,S.H., see Yellin,T.O. Burke,J.F., see Leak,L.V. 235,260 354,373 58,65,183,196 Brown,H.H., see Powers,S.R. Buckley,l.K. 128,130 Burke,J.F., see Shea,S.M. 499,516 Buckley,I.K., Ryan,G.B. 38, 43,66 Brown,J., see Baugh,R. 163, 63 Burke,J.S., Urihara,T.S., 189 Budzko, D .B., Bokisch, V.A., Macmorine, D .R. L., Movat, Brown,J.H., Kissel,J.W., MUller-Eberhard, H.J. 234, H.Z. 270,289 Lish,P.M. 556,557,562 260 Burkhalter,A., see Shore,P.A. Brown,J.H., Mackey,H.K., BUch, 0., Wagner-Jauregg, T. 352,372 Riggild,D.A., Schwartz,N.L. 528,529,535,562 Burkholder, P. M., see ligen, 555,556,562 BUhler, F., see Hesse, E. 589, C.L. 427,456 Brown, M .L., Ulett, G .A., 597, 602,611 Burleigh, M .C., see Lazarus, Stern,J .A. 534,562 Biising,K.H. 449,451 G.S. 302,310 Brown,R.A., West,G.B. 540, Bulan,M.B., see Nugent,F.W. Burns,M.W., see Bryant,D.H. 555,562 467,499,516 347,366 Brown,R.S., see Lazarus,G.S. Bull,J .P., see Sevitt,S. 504,519 Burr,V., see Winder,C.V. 531, 302,310 Bullough, W .S. 95, 100, 544, 567 Brown,W.R., see Arman,C.G. 556,562 Burrill,D.Y., see Goetzl,F.R. van 185,203 Bundy,G.L., see Nishizawa, 589,590,611 Brownstein,M., see Saavadra, E.E. 157, 175,199 Burrowes,C.E., see Habal, J .M. 352,372 Bundy,R.E., see Innerfield,1. F.M. 466,470,471,511 Brownwell,A.G., Veis,A. 220, 503,513 Burte, B., see Bessis, M. 119, 227 Bunting,S., Moncada,S., 130 Bruce,A.N. 29,63 Needleman,P., Vane,J.R. Busse, W.W., Sosman,J. 365, Bruce,C.A., Rosenthal,R.R., 155, 191 366 Lichtenstein,L.M., Norman, Bunting,S., Moncada,S., Vane, Busse, W., see Sosman,J. 356, P .S. 348,366 J .R. 155, 191,601,609 357,373 Bunting,S., see Gryglewski,R.J. Butcher,R.W., see Kelley, L.A. Bruce,S., see Mar,golis,J. 142,158,175,194 305,310 467,515 Bunting,S., see Johnson,R.A. Butculescu,1., see Cirstea, M. Brune,K., Bucher,K., Walz,D. 467,495,507 589,609 196 Bunting,S., see Moncada,S. Butler,K.D., White,A.M. Brune, K., see Glatt, K. 76, 103 198,613 184,191 Brune, K., see Glatt, M. 179, Bunting,S., see Needleman,P. Butler,W.T. 217,227 193,530,563 154,157,199,601,613 Butterfield,A., see Davies,P. Bruns,R.R., see Palade,G.E. Burberi,S., see Silvestrini,B. 277,289 34,66 548,566 Buyniski,J .P., see Fleming,J.S. Brusman,H.P., see Fu,S.M. Burch,G.E., De Pasquale,N.P. 185, 193 428,454 480, 507, 574, 585, 594, 609 Bygdeman,M., see Green,K. Bryan,A.C., see LaPierre,J.-G. Burch,P.RJ. 224,227 402,417 364,370 Burdon-Sanderson,Sir J 3, 4 Bryan,B., see Needleman,P. Burge) .J., Fearon, D. T., 154,157,199 Austen,K.F. 448, 449, 451 Cabanac,M., Stolwijk,J.A.J., Bryant,D.H., Burns,M.W., Burger,M.M. 208,227 Hardy,J.D. 630,650 Lazarus, L. 347, 366 Burger,R., Hadding, U., Cadmus,R.A., see Siegmund, Bryant,R.E., Sutcliffe, M.C. Bitter-S uermann, D. 432, E.A. 589,594,596,597,602, 111,130 447,451 614 Bryant,R.E., see DesPrez,R.M. Burger,R., Hadding,o., Caen,F.M., see Legrand,Y.J. 184,192 Schoriemmer,H.U., Brade, 179,197 Bryceson,A.D.M., see Cream, V., Bitter-Suerman,D. 279, Caen,J., see Castaldi,P.A. J.J. 242,261 289 139,191 Bryceson,A.D.M., see Green• Burger,R., see Nicholson,A. Caen,J., see Inceman,S. 165, wood,B.M. 244,262 431, 433,458 196 Bryceson,A.D.M., see Whittle, Burkard, W. P., see Pletscher, A. Caen,J., see Kubisz, P. 177,196 H.C. 244,265 141,200 Caen,J.P. 166,191 Bucher,K., see Brune,K. Burke,G., see Friedman, Y. Caen,J. P., see Legrande, Y. 589,609 396,397,399,417 272,292 Author Index 667

Caen,J.P., see Nurden,A.T. Carpenedo,F., see Fassina,G. Cater,J.C., see Wilkinson,P.C. 166,167,199 605,610 119,120,125,126,136 Ca\cott,M.A., see Miiller• Carpenter,C.B., see Hunsicker, Caulfield,J.B., see Shea,S.M. Eberhard,H.J. 235,263, L.G. 446,447,456 43,66 426,428,448,458 Carpenter,C.B., see Ruddy,S. Cava\canti, R. Q., see Rocha e Caldwell,J., Ruddy,S., Austen, 446,460 Silva,M. 489, 517, 532, 536, K.F. 438,451 Carpenter,C.B., see Strom,T .B. 566 Caldwell,J.R., Ruddy,S., 306,312 Cavanagh,R.L., see Fleming, Schur,P.H., Austen,K.F. Carr,1. 68,76, 100 I.S. 185, 193 438,439,451 Carr,J., Wilhelm,D.L. 477, Cech,K., see Pick,E. 239,264, Camargo,A.C.M., Graeff,F.G. 478,507 326,340 473,507 Carrara,C., see Garattini,S. Cerietti,A., see Stiirmer,E. Camargo,A.C.M., Ramalho• 527,528,563 477, 480, 519 Pinto,F.J., Greene,L.L. Carruthers,B.M. 125, 130, Chai,C. Y., see Lin,M.T. 621, 466,473,507 131 653 Camargo,A.C.M., Shapanka, Carson,R.W., see Rooney,P.I. Chai,L.Y., Lin,M.T., Chen, R., Greene,L.J. 473, 507 544,566 N.l., Wang,S.c. 621,650 Camargo,A.C.M., see Greene, Carson,S., see Huber, W. 549, Chain,E., see Duthie,E.S. L.J. 488,511 564 16,20 Camargo,A.C.M., see Sampaio, Carter,R.D., see Joyner, W.L. Chakrin,L. W., Krell,R.D., M.U. 465,518 583,586 Mengel,J., Young,D., Cameron, G .R., Karunaratne, Carter, R. D., see Renkin, E. M. Zaher,C., Wardell,J.R. 356, W.A.E. 207,227 583,586 357,367 Cameron,S., see Zurier,R.B. Carter,S. D. 269,289 Chalmers,R., see Dolovich,J. 356,357,373 Cartwright,G.E., see Boggs, 345,367 Chambers,A., see Halushka, Cammermeyer,J. 647, 650 D.R. 95,100 Cartwright,G.E., see Scott,J.L. P.V. 159,194 Campbell,J., see Curtis,A.S.G. 165,201 Chambers,D.A., see Salzman, 111,131 Carvalho,I.F., Diniz,C.R. E.W. 150,201 Campbell,J.A., see Turner,S.R. 473,507 Chambers,R., Zweifach,B.W. 120,135 Carvalho, I. F., see Corrado, 27,49,63 Capasso, F., Balestieri, B., A.P. 467,508 Champion,S., see Haye,B. Rosa,M. di, Persico,P., Carvalho,I.F., see Diniz,C.R. 377,380,418 Sorrentino,L. 576, 585 465,467,468,499,508 Chan,J.A., Nagasawa,N., Capasso,F., Dunn,C.J., Casley-Smith,J.R. 58, 63 Takeguchi,C., Sih,C.J. Yamamoto,S., Deporter, Casley-Smith,J.R., Florey, 390,394,395,416 D.A., Giroud,J.P., H.W. 57,63 Chand,N., Eyre,P. 354,367 Willoughby,D.A. 257,261 Casley-Smith,I.R., Window,J. Chandler,A.B. 147,191 Capasso,F., see Deporter,D.A. 583,584,585 Chandler,C., see Curtis,A.S.G. 259,261 Caspary,E.A. 319, 325, 337 111,131 Capasso,F., see Yamamoto,S. Cassone,R., see Tallarida,G. Chandra-Sekhar,N.C. 145, 257, 258,265 590,615 156,191 Chang,C., Houck,J.C. 120, Capurro,N., Levi,R. 355, 367 Castaldi, P. A., Larrieu, M. I., Caen,J. 139,191 131 Capurro,N., see Levi,R. 355, Castania,A., Rothschild, Chang,C., see Houck,J. 120, 370 A. M. 469,507 132 Cardella,C.J., Davies,P., Castania,A., see Rothschild, Chang,J., Freer,R., Stella,R., Allison,A.C. 278, 285, 289 A.M. 467,471,487,496,497, Greenbaum, L. M. 286, Cardella,C.I., see Davies,P. 518 289 275,286,289 Caste1franchi, P .L., Corrado, Chang,J., see Greenbaum,L.M. Carey, F. I., see Braude,A.I. A.P. 499,507 495,496,51 I 185,191,621,650 Castellino,F.M., see Brockway, Chang,K.-I., see Cuatrecasas, Carison,R.P., see Arman,C.G. W.J. 449,451 P. 346,367 van 185, 203, 490, 504, 520 Castilli,S., see Contreras, E. Chang, Y., see Wiseman,E. H. Carminati,P., see Lerner,L.J. 608,609 178, 181,205 551,565 Catanese, B., see Silvestrini, B. Chao,S.K., see Lim,R.K.S. Caron, G .A. 322,337 548,566 589,594,613 668 Author Index

Chapitis,J., Lepow,1. 429, Chrispijn, H., see Bonta, 1. L. Cline,M.J., see Henney,c.S. 431,452 543,561 305,306,309 Chaplin,M.F., see Sinciair,J.G. Christ,E.J., Dorp,D.A. van Cline,M.J., see Melmon,K.L. 633,634,655 383,396,416 473,491,496,497,515 Chapman,L.F., Goodell,H. Christian, C. L., see Gewurz, H. Cluff, L. E., Berthrong,M. 185, 29,63,492,507 427,454 191 Chapman,L.F., Ramos,A.O., Christian,C.L., see Gocke,D.J. Coburn,R.J., see Ballantyne, Goodell,H., Wolff,H.G. 242,262 D.L., Jr. 188,189 492,507,594,595,609 Christian,F.A., Gordon). L. Coceani,F., Pace-Asciak,C., Charache, P., see Rosen, F .S. 148,161,191 Volta, F., Wolfe,L.S. 393, 445,460 Christiansen, K., see Marcel, 416 Charbonnel,B., see Dray,F. Y.L. 380,419 Cochrane,C.G. 18, 20, 184, 402,417 Chuang,H. Y.K., see Moham• 191,345,367 Chariesworth,J .A., see Peters, med,S.F. 152, 198 Cochrane,C.G., Dixon,F.J. D.K. 447,459 Chung,E., Miller,E.J. 217,227 184,191 Chasalow, F. 1., Phariss, B. B. Cinader,B., see Ben-Efraim,S. Cochrane,C.G., Hawkins,D. 396,416 443,450 243,261 Chase,L.R., see Brodie,G.N. Cirstea,M., Suhaciu,G., Cochrane, C. G., Janoff,A. 139, 153, 191 Butculescu,1. 467, 495, 507 443,452 Chase, M. W., see Landsteiner, Claman,H. N., see Weston, W.L. Cochrane,C.G., Miiller• K. 314,339 287,294 Eberhard,H.J. 234, 261, Chatelet,L.R. de, see McCall, Clark,C.C., Veis,A. 221, 227 440,452 C.E. 441,457 Clark,E.L., see Clark,E.R Cochrane,C.G., Miiller• Chauvet,G., see Weissman,G. 49,51,53,55,63 Eberhard,H.J., Aiken, B.S. 18,25,306,313 Clark,E.R., Clark,E.L., 241,261,443,452 Chen, N. I., see Chai, L. Y. 621, Rex,R.D. 49, 51, 53, 55,63 Cochrane, C. G., Revak,S. D., 650 Clark,R.A.F., Gallin,J.L, Wuepper,K.D. 472,507 Chen-Lu,R., see Guimares,J.A. Kaplan,A.P. 127, 131, 356, Cochrane,C.G., Unanue,E.R., 466,511 357,367 Dixon,F.J. 271, 289, 299, Chervenick, P .A., LoBuglio, Clark,R.A.F., Sandler,J.A., 308 A.F. 76,93,100 Gallin,1.1., Kaplan, A. P. Cochrane,C.G., Weigle,W.O. Chervenick, P .A., see Boggs, 356, 357, 367 251,261 D.R. 95,100 Clark, W .G. 621,650 Cochrane,C.G., Weigle,W.O., Chervenick, P .A., see Roth• Clark, W.G., Cumby,H.R. Dixon,F.J. 240,242,261 stein,G. 106 631,632,650 Cochrane,C.G., Wuepper,K.D. Chervenick, P. A., see Ruscetti, Clark,W.G., Cumby,H.R., 472,507 F.W. 76,93,106 Davis, I. V., Henry,E. Cochrane,C.G., see Bokisch, Chervinick,P.A., see Weiss,H.J. 636,643,650 V.A. 234,260 169,204 Clark,W.G., see Lipton,J.M. Cochrane,C.G., see Deshazo, Chesher,G.B., see Collier, 621,626,627,653 V.c. 299,308 H.O.J. 602,609 Clark,W.R., see Webster,M.E. Cochrane,C.G., see Henson, Chesney,C.M., Harper,E., 467,520 P.M. 182-184,195,243,262, Colman,RW. 179,191 Clawson,C.C., White,J.G. 443, 444,455 Chesney, P. T., see Murphy, P.A. 186,191 Cochrane,C.G., see Kniker, 619,654 Clegg, P. c., Hall, W.F., Chess,L., see Rocklin,R.E. Pickles, V.R 604, 605, 609 W.J. 243,263 Cochrane,C.G., see Kniker, 332,341 Clementi, F., Palade,G.E. Cheung,H.S., see Flower,R.J. 34,63 W.T. 184,196,243,263,299, 375,388,396,397,413,417 Clemetson,K.J., see Jenkins, 310,345,356,360,369 Chi,H. Y., see Spitznagel,J. K. C.S.P. 139,166,196 Cochrane,C.G., see Linscott, 112,134 Cliff,W.J. 128,131 W.D. 443,457 Chignard,M., Vargaftig,B. B. Cline,M.J., Melmon,K.L. Cochrane,C.G., see Ranadive, 154,155,191 502,507 N.S. 302,311 Chignard,M., see Vargaftig, Cline,M.J., see Epstein,L. B. Cochrane,C.G., see Shazo, B.B. 155,156,203 330,338 C. V. de 444,452 Chin,K. W., see Ruddy,S. 446, Cline,M.J., see Golde,D.W. Cochrane,C.G., see Ward,P.A. 460 76,93,95,103 233-235,241,265 Author Index 669

Cochrane,C.G., see Wuepper, Collier,H.O.J., Holgate,J.A., Colten,H.R., see Breslow,J. K.D. 472,522 Schachter,M., Shorley,P.G. 434,451 Cochrane,S. G., Janoff,A 499,501,508 Colten,H.R., see Davis,J.S.lV 183, 185, 191 Collier,H.O.J., James,G.W.L. 452 Code, C. F. 13, 20 494,508 Colten,H.R., see Einstein,L. P. Coffey,J. W., De Duve,C. 285, Collier,H.O.J., Lee,I.R., 428,429,453 289 481,508 Colten,H.R., see Hall,R.E. Coffman,J.D. 594,609 Collier,H.O.J., Roy,AC. 607, 427,455 Coffman,J.D., Javett,S.L. 609 Colten,H.R., see Strunk,R. 477,508 Collier,H.O.J., Schneider,C. 428,462 Cohen,S., Ward,P.A. 319,337 501,508,598,609 Colten,H.R., see Strunk,R.S. Cohen,S., see Feinman,L. Collier,H.O.J., Shorley,P.G. 428,433,462 449,453 17,20, 501, 508 Colten, H. R., see Wyatt, H. V. Cohen,S., see Thrasher,S.G. Collier,H.O.J., Sweatman, 428,463 121,134 W.J.F. 606,609 Colten,H.R., see Zeiger,R.S. Cohen,S., see Ward,P.A. Collier,H.O.J., Warner,B.T., 353,373 119, 135, 345, 348, 359, 373 Skerry,R.J. 609 Columbo, C., see Ignarro,L.J. Cohen,S., see Yoshida,T. Collier,H.O.J., see Piper,P.J. 306,310 320,342 555,566 Colwell,1.P., Sagel,J., Penning• Cohn,J.N.,seeLimas,C.J. Collier,J.G., Karim,S.M.M., ton,R., Meeks,M., Scarpatia, 396,397,419 Robinson,B., Somers,K. R., Laminus, M. 159, 191 Cohn, V. A., Jr., see Shore, P. A 598,609 Colwell,J., see Halushka,P.V. 352,372 Collins,AJ., see Rose,A.J. 159, 194 Cohn,Z.A 68, 74, 76, 100 396, 398, 421 Colwell,J.A, see Kwaan,A.C. Cohn,Z.A., Fedorko,M.E., Collins,F. M., see Volkman, A 159, 196 Hirsch,J.G. 297,308 86,107 Comai,K., Farber,S.J., Pauls• Cohn,Z.A., Hirsch,J.G. Collins,R.D., see Hawiger,J. rud,J.R. 187,191 18,20,61,64,234,261 303,309 Comai,K., see Willis,A.L. 382, Cohn,Z.A., Wiener,E. 282, Collins,R.D., see Rafter,G. W. 422 289 619,654 Condorelli, see Tallarida,G. Cohn,Z.A., see Axline,S.G. Collins,W.F., Nulsen,F.E., 590,615 272, 278,288 Sheally,C. N. 591,609 Conroy,M.C., Orange,R.P., Cohn,Z.A, see Furth,R. van Colman,R.W. 346,367 Lichtenstein,L.M. 345, 363, 74,79,84,97,102 Colman,R. W., Shattil,S.J., 367 Cohn,Z.A., see Gordon,S. Bennett,J .S. 168, 172, 191 Conroy, M. c., see Malveaux, 72,76,103,274,282,290 Colman,R. W., see Bagdasarian, F .J. 347,370 Cohn,Z.A., see Steinman, R.A. 472,506 Contessa,A.R., see Fassina,G. R.M. 72,74,76,107,277,293 Colman,R.W., see Chesney, 605,610 Cohnheim,J. 3, 10, 11, 20, 26, C.M. 179,191 Contreras, E., Castilli,S., Qui• 28,48,63,84,100 Colman,R. W., see Lahiri,B. jada,L. 608,609 Cole,S., see Pace-Asciak,C. 469,470,514 413,420 Colman,R.W., see Webster, Cook,D.A., see Kenatin,T.P. Colledge,AJ., see Ford-Hut• M.E. 472,520 354,369 chinson,A W. 547, 563 Colten,H.R. 76, 100,427,433, Cook,C.T., Shin,H.S., Mayer, Colledge,AJ., see Smith, 452 M. M., Laudenslayer, K.A 433,452 M.J.H. 547,566 Colten,H.R., Borsos,T., Collier,H.O.J. 17,20, 501, Rapp,H.J. 427,452 Cook,G.M.W. 297,308 508, 524, 562, 588, 589, 597, Colten,H.R., Gordon,1 .M., Cook,H.W., Lands,W.E.M. 601,603,606,609 Borsos,T., Rapp,H.J. 452 392,416 Collier,H.O.J., Chesher,G.B. Colten,H.R., Parkman,R. Cook,J., Fincham, W.l., Lack, 602,609 427,452 C.H. 255,261 Collier,H.O.J., Dineen,L.C., Colten,H.R., see Alper,C.A Cook, L., see Bonnycastle, D. D. Johnson,C.A, Schneider, 430,441,442,450 607,609 C. 602,609 Colten,H.R., see Borsos,T. Cooke,T.D., Hurd,E.R., Ziff, Collier,H.O.J., Hammond, 427,451 M.,Jasin,H.E. 285,289 A.R., Horwood-Barrett,S., Colten,H.R., see Brade,V. Cooke,T.D., see Stastny,P. Schneider,C. 609 429,451 255,264 670 Author Index

Coombs,R.R.A., Fell,H.B. Comil,V., Ranvier,L. 7,20 Cream,J.J., Bryceson,A.D. M., 283,289 Corrado, A. P., Reis, M .L., Ryder,G. 242,261 Coombs,R.R.A, Gell,P.G.H. Carvalho,I.F., Diniz,C.R. Crocker,P., see Dieppe,P.A 283,289,345,367 467,508 258,259,261 Coombs, R. R. A., see Dingle, Corrado,A.P., see Diniz,C.R Crofton, R A., Diesslhoff-den J. T. 286,290 467,468,499,508 Dulk,M.M.C., Furth,vanR Coombs, R. R. A, see Lachmann, Corrado, A. P., see Castelfranchi, 79,82-86,100,101 P.J. 283,292 P. L. 499, 507, Cromartie,W.J., see Schwab, Cooney,M.H., see Spitznagel, J.H. 273,293 J.K. 268,293 Cortellaro, M., see Praga, C. 164,200 Cronan,J.E., Jr., see Bennett,J. Cooper,G. W., Prockop,D.J. 382,416 Cory,M., see Baker,B.R. 448, 220,227 Cronberg,S. 165,192 Copper,H.L., see Friedman, 450 Crone, C. 34, 63 R.M. 330,338 Cote, G., see Selye,H. 529,566 Croote,T.M., see Aken,W.G. Cooper, K. E., Cranston, W. I. Cotran,R.S. 42, 43, 45, 46,63 van 187,203 621,650 Cotran,R.S., Majno,G. 36,42, Crosby,W.H., see Yam,L.T. Cooper,K.E., Cranston, W.I., 45,46,63,486,508 70,108 Honour,AJ. 620, 646, 650 Cotran,R.S., see Widmann,J.J. Cross,M.J., see Bom,G.V.R. Cooper,K.E., Veale,W.L. 622, 72,108 584,585 633,634,646,650 Cottney,J., Lewis,A.J., Nelson, Crout,J.E., Hepbum,B., Ritts, Cooper, K. E., see Feldberg, W. D.J. 182, 192 R.E. 333,337 622,652 Cooper,K.E., see Pittman,Q.J. Coupal,C.E., see Weksler,B.B. Crowder,J.C., Martin,R.R., 621,626,647,654 176,204 White,A. 268,289 Cooper,K.E., see Veale, W.L. Courtice, F .C. 58,63 Crowley,J.H., see Rebuck,J.W. 620-622,624,629,633,634,637, Courtice, F .C., Sabine, M.S. 259,264 646,647,655 54,63 Cruikshank,C.N.D., see Sevitt, Cooper, M.D., see Stroud,RM. Cowan, R. B. T., see Warren, K .S. S. 504,519 427,462 251,265 Crunkhom,P., Meacock,S.C.R. Cooper,N.R. 430, 441, 452 Cowdrey,C.M., see Pinket, 488,502,508 Cooper,N.R., see Harpel,P.C. M.O. 77,105 Crunkhom, P., WiIIis,A L. 17, 436,455 Cox,J.P., Kamovsky,M.L. 20,173,175,192,574,585,598, Cooper,N.R., see Petz,L.D. 304,308 610 446,459 Coyne,J.A, Remold,H.G., Crutchley,D.J., Piper, P.J. Cooper,N.R., see Ziccardi,R.J. Rosenberg,S.A., David,J.R 413,414,416 426,436,463 337 Cruz,S., see Kwaan,A.C. 159, Cooperbrand,J.S., see Green, Crait,J.M., see Sheffer,A.L. 196 J.A 319,330,338 439, 449,461 Csongrady,A, Kobinger, W. Coote, E., see WiIIoughby,D.A Cranston, W.I., Duff, G. W., 354,367 536,567 Hellon,R.F., Mitchell,D. Cuatracasas, P. 323,337 Coppi,G.,Bonardi,G. 181,191 621,632,648,650 Cuatrecasas, P., Hollenberg, Corcoran, B., see Showell,H.J. Cranston, W.I., Hellon, R. F., M.D., Chang,K.-J., Bennett, 122,134,137 Mitchell,D. 640,648,649, V. 346,367 Corcoran, B. A, see Schiffmann, 650 Culbertson,J. T. 235,261 E. 121,122,134 Cranston,W.I., Luff,R.H., Culling,C.F.A 221,227 Cordeiro,R.S.B., see Roth• Rawlins, M.D., Rosendorff,C. Cumby,H.R., see Clark,W.G. schild,A.M. 496,497,518 621, 640, 651 631, 632, 643, 650 Corey,E.J., Nicolaou,K.C., Cranston, W. I., Luff, R. H., Cunningham,A.L., Hurley,J. V. Machida, Y., Malmsten, C. L., Rawlins,M.D., Wright,V.A 38,42,63 Samuelsson,B. 171, 192 641,651 Cunnington,J., see Selye,H. Corlin,R., see Schultz,}. 296, Cranston, W.I., Rawlins,M.D. 529,566 312 621, 648,651 Curran,P.F., see Delorenzo, Cormia,F.E., Dougherty,J.W. Cranston, W .1., see Cooper, K .E. R. J. 306, 308 594,610 620,621,646,650 Curry,F.E.,Mason,J.C.,Michel, Comelisse,C.J., see Papadimi• Cranston,W.I., see Duff,G.W. C. C. 581, 585 triou,J. M. 69,87; 105 636,651 Curry, F. E., Mason,J. C., Michel, Comelsen,M., see WiIIis,A.L. Crawshaw,L.I., Stitt,J. T. 625, C.C., White,I.F. 582, 585 173,205,600,601,615 629,651 Curtis,A.S.G. 109,131 Author Index 671

Curtis,A.S.G., Campbell,J., Dalldorf,F.G., see Spitznagel, David,I.R., Lawrence,H.S., Shaw,F.M. 111,131 J.K. 268,293 Thomas,L. 315,338 Curtis,A.S.G., Chandler, C., Dalmasso,A. P., see Miiller• David,J.R., Remold,H.G. Picton,N. 111,131 Eberhard,H.J. 235, 263 76,101 Curtis,A.S.G., Shaw,F.M., Damas,J., see Lecomte,J. 489, David,I.R., see Coyne,I.A. Spires,V.M.e. 111,131 514 337 Curtis,A.S.G., Sousa,M.A.B., Dames,W.see Vogt,W. 429, David,I.R., see Einstein,L.R. de 111,131 462 428,453 Cushman,D. W., see Flower, Damgaard,E., see Ungar,G. David,J.R., see Koopman, W.I. R.J. 375,388, 396, 397, 413, 502,520 324,339 417 Daniels,E.G., Krueger,W.C., David,I.R., see Koopman, Cygielman,S., Robson,J.M. Kupiecki,F.P., Pike,J.E., W.M. 358,369 529-531, 533, 535, 540, 562 Schneider,W.P. 393,416 David,J.R., see Meyers,O.L. Czarnetzki,B.M., Konig,W., Daniels,E.G., see Wallach,D.P. 331,339 Lichtenstein,L.M. 127, 131, 396, 397, 422 David,J.R., see Nathan,e.F. 345,350,351,363,367 Daniels,I.R., see Lazarus,G.S. 252,263,319,325,340 Czarnetzki, B. M., see Konig, W. 302,310 David,J.R., see Remold,H.G. 345,369 Danielson,H., see Bergstrom,S. 331,340 Czarny, P., see Samter,M. 347, 384,416 David,J.R., see Rocklin,R.E. 348,372 Danielson, H., see Hamberg, M. 321,332,341 406,418 David,J.R., see Ward,P.A. Daems, W.T., Koerten,H.K., Dannenberg, A. M., Ando, M., 118, 135, 319, 328, 332, 341 Soranzo,M.R. 101 Shima,K., Tsunda,T. 87, David,R.A., see David,J. 278, Daems, W. T., Oort,J. 184, 192 101 279,289 Daems,W.T., Wisse,E., Dannenberg,A. M., see Snyder• David,R.R., see David,J.R. Brederoo, P., Emeis,J .J. 72, man,R. 286;293 317,331,338 101 Danon,A., Heimberg,M., Oates, Davie,E. w., Ratnoff,O.D. Daems,W.T., see Ogawa,R. I.A. 380,416 211,227 72, 105 Dao Hai, N., see Vargaftig, Davies,A.T., Estensen,R., Daha,M.R., Fearon,D.T., B. B. 380,411,422 Quie,P.G. 290 Austen,K.F. 430,431, 433, DaPrada,M., Pletscher,A. Davies, G. E. 536, 562 447,457 141, 192 Davies,G.E., Holman,G., Daha,M.R., see Weiler,J.M. DaPrada,M., see Pletscher,A. Johnston,T.P., Lowe,J.S. 430,448,449,463 141,200 502, 504, 508 Dahle,I.K., Hill,E.G., Holman, D'ArcyHart, P., see Draper, P. Davies,G.E., see Billingham, R.T. 388,416 76, 101 M.E.J. 548,561 Dahlgren, M. E., see Davies, P. D'ArcyHart,P., see Karnovsky, Davies, H. T. S., see Hartley,R. E. 101 M.L. 76,104 571,586 Dailey,J. P., see Hakim,A.A. Darow,B., see Nakano,J. 408, Davies,J.D., see Neely,J. 98, 546,564 419 105 Dalakos, T.G.,seeStreeten, Dascombe,M.J., Milton,A.S. Davies, P., Allison,A. C. 76, D.H. P. 500,519 636, 642, 643, 651 101,267,272-275,289 Daldorf,F.G., see Spitznagel, Dash,A.C., see Pepys,M.B. Davies,P., Allison,A.C., Acker• J. K. 296,312 442,459 man,J., Butterfield,A., Dale,D.e., Fauci,A.S., Wolff, Dashwood, M., Feldberg, W. Williams,S. 277,289 S.M. 72,88,101 642, 644, 651 Dale,D.C., see Fauci,A.S. 88, Davies,P., Allison,A.C., Dym, Data,R., see Ward,P.A. 345, 102, 333, 338 M., Cardella,C.I. 275,286, 348, 359, 373 Dale,H.H. 12,20,334,337 289 Dale,H.H., Kellaway,C.H. Davey, M.G. 165,192 Davies,P., Allison,A.C., Hylo• 13,20 Davey,M.G., Liischer,E.F. tar, W.J. 301,308 Dale,H.H., Laidlaw,P.P. 12, 289 Davies,P., Bonney,R.J., Dahl• 20 David,J., David,R.A. 278, gren,M.E., Pelus,L., Kuehl, Dale,H.H., see Barger,G. 13, 279,289 F.A.,Humes,J.L. 101 19 David,I.R. 315,331,338 Davies,P., Fox,R., Polyzonis, Dale,H.H., see Best,C.H. 13, David,J.R., David,R.R. 317, M., Allison,A.e., Haswell, 19 331,338 A.D. 270,289 672 Author Index

Davies,P., Page,R.C., Allison, Dawson, W., see Boot,J.R Delaunay,A., Lebrun,]., Barber, A.e. 272-274,289 175,190 M. 118,131 Davies, P., Rita,G.A., Krakauer, Day,H.J., Holmsen,H. 145, DeIaunay,A., see Bazin,S. 223, K., Weissmann,G. 268,289, 151,160,164,168,170,173,192 224,227 301,308 Day,H.J., Holmsen,H., Hovig, Delbarre,F., see Kahan,A. Davies, P., see Allison,A.e. T. 141,192 253,262 76,99,124,129,260,260,269, Day,H.J., Stormorken,H., Del Bianco,P.L., see Sicuteri, 272,275,278.288 Holmsen, H. 176, 192 F. 481,519, 578,586,592, 594,596,614 Davies,P., see Cardella,C.J. Day,H.J., see Holmsen,H. Della Bella,D., Bennelli,G. 278,285,289 141,146,160,164,195,272,291 Day,N.K.B., Gewurz,H., 590,599,610 Davies, P., see Finlay, C. 287, Delmonte,L. 95,101 290 Johannsen,R., Finstad,J., Good,R.A. 437,452 Delmonte,L., Starbuck, W.C., Davies,P., see Page,R.C. 273- Day, N. K., see Ballow,M. 442, Liebelt,R.A. 95,101 275,292 450 Delorenzo,RJ., Walton,K.G., Davies, P., see Schorlemmer, Day,N., see Geiger,H. 434, Curran, P. F., Greengard, P. H.U. 279,293 454 306,308 Davies, P., see Temple,A. 270, Day,N.K.B., see Moncada,B. Delver,A., see Bonta,l.L. 551, 293 426,458 561 Davis,A.B., see Park,B.H. DeBernardo, R., see Ishizaka, T. Dembinska-Kiec,A., Zmuda, 305,311 347,369 A., Krupinska,J. 607,610 Demeo,R., see Goldstein,S. Davis,A.E., see Einstein,L. P. DeBernardo,R., see Lichten• 528, 529, 531, 534, 538-540, 429,453 stein, L. M. 349,370 555,563 Davis,A.T., see Becker,E.L. DeBernardo, R. M., Askenase, Denduchis, B., see Kefalides, 124,130 P., Tauben,D., Douglas,J. N.A. 218,229 Davis,I.V., see Clark,W.G. 359,367 Deneau,G.A., Waud,R.A., 636,643,650 DeCock, W., see Verhaegen,H. Gowdey, C. W. 596,601,605, Davis,J.S., see Einstein,L.P. 358, 365, 373 DeCree,J., see Verhaegen,H. 610 429,453 De Pasquale, N. P., see Burch, 358,365,373 Davis,J.S.lV, Colten,H.R., . G.E. 480,507 DeDuve,e. Alper,C.A. 452 18,20,295,296, De Petris,A., see Allison,A.e. 308,482,508 Davis,N.e., see Spitzer,R.E. 269,288 DeDuve,e., Berthet,J., Hers, 430,447,462 Deporter,D.A., Capasso,F., H.G., Dupret,L. 295,308 Willoughby,D.A. 259,261 Davis,N.C., see Vallota,E.H. DeDuve, C., Pressman, B. C., 447,462 Deporter,D.A., see Capasso,F. Gianetto, R., Wattiaux, R., 257,261 Davis,R.B. 185, 192 Appelmans,F. 482,508 Deporter,D.A., see Yamamoto, Davis,R.B., Meeker, W.R., DeDuve,C., see Aronson,N.N., S. 257, 258, 265 McQuarrie,D.G. 185,192 Jr. 285,288 Derenzo,E.C., see Ablondi,F.B. Davis,R.B., White,J.G. 141, DeDuve,e., see Baggiolini,M. 449,450 192 268,288,296,307 Dervinis,A., see Rosenthale, Davison,e., GUy,J.L., Levitt, DeDuve,C., see Coffey,J.W. M.E. 186,201, 598,614 M., Smith,P.K. 607,610 285,289 Deschmukh,A.D., Nimni,M.E. Davison,P., see Willis,A.L. DeDuve, e., see Fowler, S. 285, 217,228 153, 168, 170, 175, 177, 205, 290 Deshazo,C.V., Mcgrade,M.T., 627,631,645,646,655 DeGaetano, G., see Donati, Henson, P. M., Cochrane, Dawkins,P.D., see McArthur, M.B. 162, 192 e.G. 299,308 J.N. 558,565 Dehm,P., Prockop,D.J. 218, De Souza,Z.A., see Garcia• Dawkins,P.D., see Smith, 228 Leme,J. 552,563 M.J.H. 413,421 Dehm,P., see Jimenez,S.A. DesPrez,R.M., 184, 192 Dawson,W., Lewis,R.L., Mac• 221,228 DesPrez,R.M., Bryant,R.E. mahon,R.E., Sweatman, Deisseroth,A., see Strom, T. B. 184, 192 W.J.F. 410,416 306,312 DesPrez, R M., Horowitz, H.I., Dawson,W., Ramwell,P.W., Dekaris,D., Smerdel,S., Veselic, Hook,E.W., Jr. 184, 185, Shaw,J. 408,416 B. 319,338 192 Dawson, W., Starr, M.S., West, Delanay,A., see Bazin,S. 300, DesPrez, R M., Marney, S. R., G.B. 494,495,503,508 307 Jr. 172, 184, 192 Author Index 673

DesPrez,R. M., see Horowitz, Dierich,M. P., Ferrone,S., Diniz,C.R., see Corrado,A P. H. I. 184, 185, 195 Pelligrino, M. A., Reisfeld, 467,508 Desser,R.K., see Deykin,D. R.A. 441,452 Diniz,C.R., see Deutsch,H.F. 142,192 Dierich, M. P., see Bokisch, V.A. 471,473,508 Deutsch,H.F., Diniz,C.R. 428,451 Di Pasquale,G., Girerd,R.J. 471,473,508 DiesslholT-den Dulk, M. M. c., 540,562 De Vos,c.J., see Bonta,I.L. see Crofton,R.A. 79, 82-84, Di Pasquale,G., Girerd,R.J., 490, 507, 528-530, 532, 535, 86,100,101 Beach, V. L., Steinetz, B. G. 537, 538, 540-542, 545, 546, DiesselholT-den Dulk, M. M. C. 531,537,538,562 550,551,561,562 see Furth,R., van 70,72,74, Di Pasquale,G., Rassaert,G., Dewald,B., Rindler-Ludwig,R., 79,82-84,86,102 Richter,R., Welaj,P., Tripp,L. Bretz, U.,Baggiolini,M. 268, Dillard, G. M., see Bodel, P. 553,562 270,290 551,561 Di Rosa,M., Giroud,J.P., De Wald,H.A., see Nicolaides, Dinarello, C. A., Bodel, P. T., Willoughby,D.A. 488, 502, E.D. 464,500,516 Atkins,E. 619,651 503,508,527,528,530,536,562 Dey,P.K., Feldberg,W., Gupta, Dineen,L.C., see Collier,H.O.J. Di Rosa,M., Sorrentino,L. K.P., Milton,A.S., Wend• 602,609 488,502,508,578,585 landt,S. 638,642,643,651 Dingle,J., see Weissmann,G. Di Rosa,M., Willoughby,D.A. Dey, P. K., Feldberg, W., Wend• 482,521 488,503,508 landt,S. 640,651 Dingle,J.T., Barrett,A.J., Poole, Dixon,F.J.,Oldstone,M.B.A, Dey, P. K., Feldberg, W., Gupta, A R., Stovin, P. 283,290, Tonietti,G. 243,261 P.K., Wendlandt,S. 621, 300,308 640,644,646,651 Dingle,J. T., Barrett,A.J., Dixon,F.J., see Cochrane,C.G. Deykin,D., Desser,R.K. 142, Weston,P.D. 283,290,300, 184, 191, 240, 242, 261, 271, 192 308 289,299.308 Deykin,D., see Ream, V.J. Dingle, J. T., Fell, H. B., Coombs, Dixon,F.J., see Lerner,RA 184,200 R.R.A. 286,290 445,457 Dias da Silva, W., Eisele,J. W., Dingle,J.T., Poole,A.R., Laza• Dixon,G.H., see Louie,A.J. Lepow,I.H. 234,261,440, rus,G., Barrett,A.J. 285, 306,311 452 286.290 Dobbie,J., see Kwaan,A.C. Dias da Silva, W., Lepow,I.H. Dingle,J. T., Poole,AR, Laza• 159, 196 234,261,440,452 rus,G.S., Barrett,A.J. 300, Doherty, P.C., see Bianden,R. V. Dias da Silva, W., see Beraldo, 308 76,100 W.T. 14,19,573,585 Dingle,J.T., see Barrett,A.J. Dolovich,l., Hargreave,F. E., Dias da Silva, W., see 297.307 Chalmers,R., Shier,K.J., Donaldson,V.H.G. 440, Dingle,J.T., see Lachmann,P.J. Gauldie,J., Bienenstock,J. 453 283,292 345,367 Dibona,D.R., see Harris,E.D., Dingle,J.T., see Lazarus,G.S. Domenjoz, R., Theobald, W., Jr. 446,455 300,310 Morsdorf, K. 528,562 Dickerson,G.D., Engle,R.J., Dingle,J. T., see Morrison, Guzman,F., Rodgers,D.W., Domingo,E.C., Warren,K.S. R.I.G. 179,198,301,311 Lim,R.K.S. 591,610 251, 261 Dingle,J.T., see Poole,A.R. Domingo,E.C., see Warren, Dickerson,G.D., see Lim, 283,292 K.S. 251,265 R.K.S. 22,481,501,514,589, Dingle,J.T., see Weston,P.D. 590,600,603,612 Domington,K.J., see Ellerson, 300,313 Dieminger, L., see Brade, V. J.R. 426,453 438,451 Diniz, C. R., Carvalho, I. F. Donaldson, V.H., Evans,R.R Dieminger,L., see Vogt, W. 467,508 439,445,453 429,447,462 Diniz,C.R, Carvalho, I. F., Reis, Donaldson, V. H., Meder, E., Dieppe, P.A., Huskisson,E.C., M.L., Corrado,A.P. 467, Rosen,F.S., Kretschmer, Crocker, P., Willoughby, 468,499,508 K.W., Lepow,I.H. 440,453 D.A., Balme,H. W. 258,259, Diniz, C. R., Carvalho, I. F., Donaldson, V. H. G., Ratno/f, 261 Ryan,J., Rocha e Silva,M. O.D., Dias da Silva,W., Dieppe,P.A., Willoughby,D.A, 465,508 Rosen,F.S. 440,453 Huskisson,E.C., Anigoni• Diniz,C.R., see Carvalho,I.F. Donaldson, V. H., Rosen,F. S. Martelli, E. 261 473,507 439,453 674 Author Index

Donaldson,V., see Rosen,F.S. Drazen,J.M., Austen,K.F. Dunn,C.J., see Capasso,F. 445,460 364,367 257,261 Donati, M. B., Palester-Chlebo• Dreyfus, D., see Meyer,D. 166, Dunn,C.J., see Velo,G. P. 257, wczyk,M., DeGaetano, G., 198 265 Vermylen,J. 162,192 Dreyfus,M.D., see Jenkins, Dunn,C.J., see Yamamoto,S. Dore,J., see Vernon-Roberts,B. C.S.P. 163,166,196 255, 257, 258, 265 259,265 Dresch, c., see Najean, X. 165, Dupree,E., see Grant,J.A. 348, Dorfman,A 216,228 199 351,368 Dornfest, B. S., see Gordon, A. S. Dreser,H. 602,610 Dupret,L., see De Duve,C. 95, 103 Dry,R.M.L., see Armstrong,D. 295,308 Dorp,D.A., van 377, 395,417 480,506,591,593,608 Durant,C.J., see B1ack,J. W. Dorp,D.A, van, Beerthuis, Dubas,T.C., Parker,J.M. 607, 333,337,354,366 R.K., Nugteren,D.H., Vonke• 610 Durant,G.J., GanelIin,C.R., man,H. 384,417 Dubois-Raymond, 7 Parsons, M. E. 354, 367 Dorp,D.A., van, see Christ,E.J. Duddley,H.W., see Best,C.H. Durant,G.J., see Black,J. W. 383,396,416 13,19 14,19 Dorp,D.A., van, see Nugteren, Duell,E.A., see Hammarstrom, Durant,G.J., see Brimblecombe, D.H. 386,387,393,395,420 S. 375,405,418 R. W. 355,366 Dorp,D.A, van, see Vonkeman, Duff, G. W., Cranston, W.I., Durant,G.J., see Parsons,M.E. H. 377,380,422 Luff, R. H. 636,651 354,371 Dorpat,T.L., Holmes,T.H. Duff,G. W., see Cranston, W.1. Durham,N.C., see Menkin,V. 593,610 621,632,648,650 530, 543,565 Dougherty,J. W., see Cormia, Dukor,P., see Weissmann,G. Duthie,E.S., Chain,E. 16,20 F.E. 594,610 258,265,303,312 Dvorak,A. M., Hammond,E., Douglas,J., see DeBernardo, Dumonde,D.C., G1ynn,L.E., Dvorak, M. F., Karnovsky, R.M. 359,367 252, 254, 261 M.J. 324,338 Douglas,W.W. 95,101,349, Dumonde,D.C., Howson,W.T., Dvorak,A. M., Mihm, M. C., Jr, 352-354,360,361,367 Wolstencroft,R.A. 321,338 Dvorak,H. F. 359,367 Dourmashkin, R. R., see Dumonde,D.C., Kelly,R.H., Dvorak,A.M., see Dvorak,H.F. Humphrey,J.H. 233,262, Preston, P.M., Wolstencroft, 348,359,367 435,456 R.A. 77,101 Dvorak,H.F. 315,338 Douwes,F.R. 18,20 Dumonde,D.C., Page,D.A, Dvorak,H.F., Dvorak,A.M. Downing,D.T. 141, 192 Matthew,M., Wolstencroft, 348,359,367 Downing, D. T., Barve,}. A., R.A. 331,338 Dvorak,H.F., see Dvorak,AM. Gunstone,F. D., Jacobsberg, Dumonde,D.C., Wolstencroft, 359,367 M., Lie, K.J. 414,417 R.A., Panayi,G.S., Matthew, Dvorak,H.F., see Richerson, M., Morley,J., Howson,W.T. B. B. 314,341 Downing,D.T., see Ahern,D.G. 317,338 Dvorak,H.F., see Richerson, 141,189,396,415 Dumonde,D.C., see Bray,M.A. H.B. 264 Doyle,B.B., see Reid,K.B.M. 320, 325, 327, 332, 333, 337 Dvorak,H.F., see Ward,P.A. 426,460 Dumonde,D.C., see Glynn,L.E. 345,348,359,373 Dragstedt, C. A., Gebauer• 210,228 Dvorak, M.F., see Dvorak,A M. Fuelnegg, E. 13, 20 Dumonde,D.C., see Kelly,R.H. 324,338 Dragstedt,C.A., Rocha e Silva, 319,339 Dym,M., see Davies,P. 275, M. 20 Dumonde,D.C., see Morley,J. 286,289 Dragsted t, C. A., see Arellano, 317,320,331,334,340 Dyrud,O.K., see Briseid,K. M.R. 15,19 Dumonde,D.C., see Wolsten• 489,507 Dragstedt,C.A., see croft,R.A. 320-322, 342 Rocha e Silva, M. 15, 16,24 Duncan, H. L., see Trapnell, Eakins, K. E., Whitelocke, Drakontides,A. B., Gershon, J. E. 500,520 R.A .F., Perkins, E. S., Bennett, M.D. 361,367 Duncan, W. A. M., see Black, A., Unger,W.G. 175,192 Draper, P., D'ArcyHart, P. 76, J. W. 14, 19, 333, 337, 354, Eakins, K. E., see Needleman, P. 101 366 154,157,199 Dray,F., Charbonnel,B. 402, Duncan, W.A. M., see Brimble• East,P.F., see Potts,W.J. 626, 417 combe,R. W. 355,366 627,635,564 Dray,S., see Lolekha,S. 319, Duncombe, W. G., see Blackwell, Eastoe,J.E. 211,216,228 325,339 G.J. 159, 178, 190,411,416 Ebbe,S. 165,192 Author Index 675

Ebbe,S., see Terada,H. 186, Eisen,A.Z., see Koob,J. T. 287, Ellman, L., see Root, R. K. 432, 203 291 460 Ebert,R.H., Florey,H.W. 84, Eisen,S.A., see Sullivan,T.J. Ellner,J.]., see Rosenthal,A.S. 101 349,373 77, 106 Ebert,R. H., see Moses, J. M. Eisen, V., 466, 470, 473, 490, Elmes,P.C. 98,101 112,133 498,509 Elsbach,P. 177,192 Eckersley, B. J., see Ashworth, Eisen, V., Greenbaum,L., Lewis, Elsbach, P., Rizack,M.A. 177, L.A.E. 332,337 G. P. 502,509 192 Eckert,1., see Fritz, H. 469, Eisen, V., Loveday, e. 489,502, Elsbach, P., see Patriarca, P. 510 509 382,420 Eisenman,J.S. 621,630,651 Edelman, I. S., see Peterson, Elsden,D.F., see Partridge, Eisenstein,R., see Rent,R. 425, M.J. 305,311 S,M. 222,229 Edelson, P. J., Fuden berg, H. H. 460 Emeis,J.l., see Deams,W.T. Eisler,M., see Gordon,AS. 124,131 72,101 95, 103 Edery, H., Lewis,G. P. 473, Emele,J.F., Shanaman,J. Ek bladg, L., see Hendricks, 482, 487, 497, 508, 594, 610 602,605,610 e. H. 625, 652 Edington, G. M., see Allison, Emmelin,N., Feldberg, W. Elfenbein,G.J., see Oppenheim, Ae. 244,260 596,610 J.1. 77,105 Editorial, 225,228 Emmines,l P., see Skaer,R.J. Elg, P., see Hamberg, U. 467, Edwall, L., see Olgart, L. 605, 141,201 512 Encyclopaedia Britannica 21 613 Eling,T.E., see Anderson,M.W. Engle,R.l., see Dickerson,G.D. Edwards,B., see Hurley,J. V. 414,415 591,610 29,38,42,64 Eiing,T.E., see Parkes,D.G. Engle, R.]., see Lim, R. K. S. Edwards,J.G., see Wadell,A.W. 393,396,420 22,481,501,514,589,590,600, 111,135 Ellerson,l.R., Yasmean,D., 603,612 Eechout,Y., see Vaes,G. 301, Painter,R.H., Domington, Engleman, E. G., Greenbaum, 312 K.1. 426,453 L. M. 496,509 Egan,R. W., see Kuehl,F.A. Elliot,D.F., Horton,E. W., Enzinger,F. M., Lattes,R., 554,565 Lewis,G.P. 16,21,477,480, Egbert,L.D., see Smith,G.M. 509,574,585 Torloni,H. 224,228 Eppinger,H. 13,21 596,615 ElIiot,D.F., Lewis,G.P. 478, Egdahl,R., see Melby,}. 550, 480,509 Epps,D.E. van, WiIliams,J. 565 ElIiot,D.F., Lewis,G.P., 137 Ehringer,H., Herzog,P., Horton,E.W. 16,21,464, Epps,D.E. van, see Holley,T.R. Konzett,H. 17,20,477,508 474,509 126,132 Ehrlich, H. P., Bornstein, P. Elliot, D. F., Lewis, G. P., Epstein,L.B., Cline,M.l., 220,228 Smyth,D.e. 464,509 Menigan, T. e. 330, 338 Ehrlich, H. P., Ross, R., Born• Elliot, P. N. C., Bolam,J. P., Epstein,L. P. 76,101 stein, P. 220,228 Ford-Hutchinson,A. W., Erbe, R. W., see Krane, S. M. Ehrlich, H. P., see Bornstein, P. Smith,M.l.H. 547,562 220,229 220,227 Eliiott,P.N.e., Ford-Hut• Erbert,R.H., see Graham,R.e. Eichbaum, F., see Spanoudis,S. chinson,A W., Smith,M.J.H. 474,477, 482, 511 236,264 547,563 Erdos,E.G. 21, 185, 193,465, Eichmann, K. 359,368 Elliot, P. N. e., see Bolam,l P. 473,500,509 Eigner, E. A., see Piez, K. A. 229 488,507,547,561 Erdos,E.G., Renfrew,A.G., Einstein,L. P., Alper,C.A., Elliot, P. N. e., see Ford-Hut• Sloane,E.M., Wohler,J.R. Block,K.J., Herrin,J.T., chinson,A. W. 547, 558, 563 473,509 Rosen,F.S., David,J.R., Eliiott,P.N.C., see Smith, Erdos,E.G., Sloane,E.M. 473, Colten,H.R. 428,453 M.].H. 547,566 509 Einstein,L. P., Hansen, P.J., Elliot,R.B., see Samuels,e.E. Erdos,E.G., Sloane,E.M., Ballow,M., Davis,A.E., 168,172,201 Wohler, I. M. 496, 509 Davis, J. S., Alper, e. A., Rosen, Ellman, L., Green, I., Frank, M. Erdos,E.G., Wohler,lR., F.S., Colten,H.R. 429,453 453 Levine,M.1. 473,509 Einstein,L. P., Schneeberger, Ellman, L., Green,1., Judge, F., Erdos, E. G., Yang, H. Y. T. E.E., Colten,H.R. 428, 453 Frank,M.M. 443,453 472-474,503,509 Eisele,}. W., see Dias da Silva, ElIman,L., see Frank,M.M. Erdos, E. G., see Kakimoto, T. W. 234,261,440,452 427,449,453 302,310 676 Author Index

Erdos,E.G., see Oshima,G. Eyre, P. 355,368 Fearon,D.T., see ShefTer,A.L. 473,516 Eyre,P.,seeChand,N. 354,367 461 Erdos,E.G., see Werie,E. 473, Fearon,D.T., see Weiler,J.M. 521 430, 448,463 Erdos,E.G., see Yang,H.Y.T. Factor,A., see Weiss,H.J. Fedorko,M.E., see Cohn,Z.A. 473,522 169,204 297,308 Ericsson,J. L. E., see Helminen, Fahimi,H.D. 72.102 Fedorko,M.E., see Furth,R. H.J. 297,309 Fahimi,H.D., see Widmann,J.J. van 72, 83, 102 Ertel,N., see Rent,R. 425,460 72, 108 Feigin,1. 647,651 Esquenazi, V., see Jensen,J.A. Fakunle,F.A., see Whittle,H.C Feinman,L., Cohen,S., Becker, 119, 122, 132 244.265 E.L. 449,453 Essen,J.V. van, see Miert,A.S. Falkenhein,S., see Jakschik, Feldberg, W. 16,593,610,632, van 640,655 R .A. 362, 369 644,645,651 Essner,E., see NovikofT,A.B. Fallah,H.A., Maillard,l.L., Feldberg, W., Gupta, K. P. 297,311 Voison,G.A. 358,368 637, 638, 651 Estensen, R., see Davies, A. T. Fanciullacci, M., see Sicuteri, F. Feldberg,W., Gupta,K.P., 290 467, 481, 501, 519, 578, 586 Milton,A.S. 651 Estensen, R., see Goldberg, N. Farber,SJ., see Comai,K. Feldberg,W., Gupta,K.P., 354,368 187, 191 Milton,A.S., Wendlandt,S. Estensen,R.D., Hill,H.R., Farmer,J .B., see Augstein,J. 621,638,641,644,651 Quie,P.G., Hogan,N., 363,366 Feldberg, W., Miles,A.A. 573, Goldberg,N.D. 125,131 Farquhar, M., see Bainton, D. F. 585 Estensen,R. D., Plageman, 297,307 Feldberg, W., Myers,R.D. P.G.W. 269,290 Farquhar, M.G., Palade,G.E. 637,643,651 Estensen,R.D., White,J.G., 31,63 Feldberg, W., Myers,R.D., Holmes, B. 268, 290, 298, Farquhar, M.G., see Bainton, Veale,W.L. 642,643,651 308 D.F. 297,307 Feldberg, W., Saxena, P. N. Estensen,R.D., see Becker,E.L. Farquhar, M.G., see Friend, 617, 621, 623, 624, 626, 627, 124,130 D.S. 297,308 633, 635, 637, 642, 646, 651, Estensen,R.D., see Hill.H.R. Farrow,1 .F., Willis,A.L. 652 356,357,369 145,193 Feldberg, W., Smith,A. N. 578, Estensen,R.D., see White,J.G. Fasciolo,J. C, Halvorsen, K. 585 298,313 467,509 Feldberg,W., Veale,W.L., Estensen,R.D., see White,R.G. Fassina, G., Carpenedo, F., Cooper, K.E. 622, 652 268,294 Santi,R. 605,610 Feldberg, W., see Bartosch, R. Evans,D.J., see Peters,D.K. Fassina,G., Contessa,A.R. 13,19 447,459 605,610 Feldberg, W., see Dashwood,M. Evans,G., Packham, M.A., Fauci,A.S., Dale,D.C 88,102, 642,644,651 Nishizawa,E.E., Mustard, 333,338 Feldberg,W., see Dey,P.K. J.F., Murphy,E.A. 141,160, Fauci,A.S., WolfT,S.M. 99, 102 621, 638, 640, 642-644, 646, 193 Fauci,A.S., see Dale,D.C 72, 651 Evans,G., see Mustard,J.F. 88,101 Feldberg, W., see Emmelin, N. 172,183,198 Fawcett, A.A., see Hales,J.R.S. 596,610 Evans,L.,seeAli,S.Y. 301,307 625,629,652 Feldman,J .D., see Najarian,J.S. Evans,R. 77, 101 Fearn,HJ., Karady,S., West, 334,340 Evans,R., Alexander,P. 77, G.B. 556,557,563 Feldman,M., Schrader,J.W., 102 Fearon,D.T., Austen,K.F. Boylston,A. 76, 102 Evans,R., see Wagner, W.H. 429-433,448,453 Feldman, T.J., see Pick,E. 250, 68, 107 Fearon,D.T., Austen,K.F., 264 Evans,R.R., see Donaldson, Ruddy,S. 429,431,433,436, Fell,H.B., Barratt,M.E.J. V.H. 439,445,453 448,453 284,290 Evans, W.H., see Mangianello, Fearon,D.T., see Burge,J.J. Fell,H.B., see Coombs,R.R.A. V. 305,311 448,449,451 283,289 Everson,L.K., see Ruddy,S. Fearon,D.T., see Daha,M.R. Fell,H.B., see Dingle,J.T. 286, 446.460 430,431,433,447,452 290 Ewart,M.R., see Kay,A.B. Fearon,D.T., see Ruddy,S. Fell,H.B., see Lachmann,PJ. 120.132 446,447,460,461 283,292 Author Index 677

Fell,H.B., see Poole,A.R. 284, Fichman,M., see Henriques, Fletcher,A. P., see Alkjaersig. 285,292 O.B. 465,469,512 N. 449.450 Fell,H.B., see Weissmann,G. Fiedler,F., Werle,E. 470,510 Flickinger, R. A., see Klose,1. 482,521 Fietzek,P.P., Kuhn,K. 217, 208,229 F eltkamp-V room, T. M., see 228 Flores,l .• Witkum,P.A., Ter Laan,B. 440,462 Fillmer, H. M., see Robertson, Beckman,B., Sharp,G.W.G. Ferber, E., see Fischer, H. 111, P.B. 302,311 305.308 131 Fink, E., see Sampaio, M. U. Florey,H. 1,4 Ferencik,M., Stefanovic,l 465,518 Florey, H .. see lennings, M. A. 300,308 Fink,M.A. 15,21 34,65 Fernandez,L.A., see Hempel, Finlay, e., Davies, P., Florey, H. W. 28, 29,63 K.H. 551,564 Allison,A.C. 287, 290 Florey,H.W.. Grant. L. H. 49, Ferreira,S.H. 145, 173, 175, Finley,T.N., see Golde,D.W. 63, 111, 114,131 193, 481, 484, 503, 509. 590, 76,93,103 Florey, H. W., see Casley-Smith, 594,595,598-601,604,610 Finstad,l., see Day,N.K.B. 1.R. 57,63 Ferreira,S.H., Harvey,E.A., 437,452 Florey.H.W., see Ebert,R.H. Vane,J.R. 600,602,610 FinstadJ, see Gewurz, H. 84,101 Ferreira,S.H., Moncada,S., 437,454 Florey,H. W .• see Marchesi, Parsons,M., Vane,l.R. 527, Firkin, G. B., see Howard,M.A. V.T. 51. 66, 111. 133. 584. 563,575,576,585 166,195 586 Ferreira,S.H., Moncada,S., Fisburne, 1. 1., see Hendricks, Florey.H.W., see Pullinger, Vane.l.R. 17,21, 178, 193. e. H. 625,652 B.D. 58.66 488, 501, 503, 509, 510, 575, Fischer, H., Ferber, E .• Haupt, I , Florey, Lord 63 585, 589. 590, 592. 594, 595, Kohlschiitter,A., Mododell, Flower.R.l 153,193.374,383, 596, 597, 599, 600, 604, 605, M., Munder.P.G., Sonak,R. 396. 397. 399, 400. 413, 417. 606-608,610 111,131 632,652 Ferreira,S.H., Rocha e Silva,M. Fischer, H .• see Lohmann• Flower, R. l, Blackwell, G. l 473,503,510 Matthes,M.L. 77, 104, 319, 381,411,417 Ferreira,S.H., Vane,l.R. 325,339 Flower,R.l, Cheung.H.S., 375, 406, 408, 417, 472, 473, . Fischer, P., Lecomte,l. 183, Cushman. D. W. J'15. 388. 510,598,607,608,610 193 396.397.413,417 Ferreira,S.H., see Greene,L.l Fisher,D., see Ahkong.Q.F. Flower.R.l. Gryglewski,R .• 488,511 115,129 Herbaczynska-Cedro, K .. Ferreira,S.H., see Moncada,S. Fisher, D. B., Mueller, G. C. Vane. 1 .R. 153,193 154, 173, 198,488,515, 588, 322,338 Flower,R.l. Harvey.E.A.. 589, 590, 592, 594, 595, 597, Fisher,E.R. 98,102 Kingston, W. P. 173. 193. 600,601,604,606,613 Fitzgerald,M.l.T. 592,610 375.417, 577,585 Ferreira, S. H., see Rocha e Silva, Fitzpatrick, F. A., Gorman, R. R. Flower.R.l .• Kingston. W. P. M. 471,517 157, 193 175.193 Ferreira,S.H., see Staszewska• Fiume,L., see Barbanti-Bro• Flower,R.l., Vane,l.R. 153. Barczak, 1. 600,615 dano,G. 267,288 193. 400, 417. 607, 610, 645, Ferreira,S. H., see Ubatuba,F.B. Fjallebrant,N.,Iggo,A. 592, 646,652 181-183,203 610 Flower,R.l., see Blackwell. Ferrendelli,l.A., see Needleman, Flanagan,T.D., see Ward,P.A. G.l. 159, 178, 190. 381. 396. P. 154, 157, 199 119,135 397, 400, 409, 411. 414. 415. Ferri, S., Sangostino, A., Braga, Flataker, L., see Arman, C. G. 416 P.e., Galatulas,I. 608, 610 van 480, 503, 504, 520, 602, Flower. R. l. see Gryglewski. Ferris,B.. see Nachman,R.L. 605,615 R.I. 142.158.175.194 139,176,199,272,292 Flataker,L., see Winter,C.A. Flower.R.L see Nijkamp,F. P. Ferrone,S., see Dierich,M.P. 480, 522, 531, 567, 597, 602, 412.420 441,453 603,616 Flower, R. 1., see Pollard). Feuerstein,A., see Reimers,H.l Flax, M. H., see Tevethia, S. S. 402,421 141,200 77, 107 Forster. O. 301,308 Fiasconaro,l.E., see Sherman, Fleischhauer,K. 647,652 Folds,lD .• Welsh,LR.H., H. 601,602,614 Fleming,l S., Buyniski,l. P., Spitznagel, l K. 268. 290 Ficham, W.l., see Cook,J. 255, Cavanagh, R. L., Bierwagen, Folds,J.D., see Spitznagel,l.K. 261 M.E. 185,193 268, 293, 296, 312 678 Author Index

Folk,J,E" see Gladner,J.A Fossler,D.E., see Lipton,J.M. Freeman,J.J. 256,261 482,511 621, 624, 625, 635, 637, 653 Freeman,P.c., see McArthur, Fong,].S.c., Good,R.A. 236, Fostiropoulos, G., Austen, K. F., J. N. 547,565 246,247,261,448,453 Bloch,K.J. 446,453 Freer,R., see Chang,J. 286, Forchielli,E., see Tomlinson, Fothergill,l E., see Barkas, T. 289 R. V. 203,396,422 426,450 Freer, R., see Greenbaum, L. M. Ford,D.M. 630,652 Fotino,M., see FU,S.M. 428, 495, 496, 511 Ford,W.H., Ashworth,L.A.E., 454 Freer, R. J., see Showell, H. J. Inder, S. 320, 338 Fowler,S., De Duve,C. 285, 122,134, 137 Ford, W. H., see Ashworth, 290 Freiman, D. G., see Braunstein, L.A.E. 332,337 Fox,A., Glynn, L. E. 255,261 H. 99,100 Ford, W. L., Sedgley, M., Fox, R., see Davies, P. 270,289 Freitas,A., Sousa,M.AB., de Sparshott, S. M., Smith, M. E. Fox,RH., Goldsmith,R., Kidd, 112,131 112,131 D.J., Lewis,G.P. 477,510, Freitas,J.O., see Prado,1.L. Ford-Hutchinson,A. W., Elliott, 574,585,594,611 466,517 P. N. c., Bolam,J. P., Smith, Franchi,G., see Sicuteri,F. Frens,J., see Miert,A.S., van M.J.H. 547,563 467, 481, 501, 519, 578, 586, 626,655 Ford-Hutchinson,A. W., 592,594,596,614 Freund,]., Miles,A.A, Mill, Insley, M. Y, Elliott, P. N. C., Franchi, P. L., del B., see Sicuteri, P.J., Wilhelm,D.L. 477, Srurges, E. A., Smith, M. J. H. F. 598,606,614 478,510 547,558,563 Francis,L., see Atkins,E. 619, Frey,E.K. 470,510 Ford-Hutchinson,A. W., Smith, 649 Frey,E.K., Kraut,H., Schultz,F. M.J.H., Elliott,P.N.C., Franciulacci,M., see Sicuteri,F. 470,510 Bolam,J. P., Walker,1.R., 592,598,606,614 Frey,E.K., see Kraut,H. 470, Lobo,AA., Badcock,J. K., Franco,M., Hanson,J.H., 514 Colledge,A.J., Billimoria, Morley,J., Wolstencroft,R.A. Frey,M., von 591,615 F.J. 547,563 328,338 Fried,]., Mehrer,M.M., Gaede, B.J. 412,417 Ford-Hutchinson,A. W., Smith, Franco,M., Kelly,R., Moriey,J. Friedberg,K.D., Garbe,G., M.J.H., Walker,J.R. 175, 327-329,338 Griitzmacher,]. 449, 454 193 Frank,M.M., May,]., Garther, Friedberger,E. 13,21,440,454 Ford-Hutchinson,A. W., see T., Ellman,L. 427, 449, 453 Friedemann, U. 13,21 Bolam,]. P. 488,507, 547, Frank,M.M., Sergent,J.S., Friedman, C. A., see Bennett, 561 Kane,M.A, Alling,D. W. A 393,416 Ford-Hutchinson,A W., see 453 Friedman,R.M., Cooper,H.L. Elliott, P. N. C. 547, 562, Frank,M.M., see Ellman,L. 330,338 563 443,453 Friedman,Y., Lang,M., Burke, Ford-Hutchinson, A W., see Frank, M. M., see Gelfand, M. C. G. 396,397,399,417 Smith,M.J.H. 185,202, 447,454 Friedman,Z., Lamberth,E.L., 547,566 Frank,M.M., see Jaffe,C.J. Stahlman, M.T., Oates,J.A F orell, M. M. 499,510 449,456 159,193 Forell,M.M., see Werie,E. Frank,M.M., see Kane,M.A Friend,D.S., Farquhar,M.G. 470,471,521 246,262 297,308 Foreman,J.D., Mongar,J.L., Frank,M. M., see Leddy,J. P. Friesen,A.D., see Ashton,F.E. Gomperts,B.D. 349,368 434,457 545,560 Foriot,P., see Hureau,J. 499, Frank,M.M., see May,J.E. Frimmer, M. 477, 510 513 457 Fritz,H., Eckert,!., Werie,E. Forristai,J., see Spitzer,RE. Frank,M.M., see Root,R.K. 469,510 430,447,462 432,460 Frolich,A, Meyer,H.H. 593, Forristal,]., see Vallota,E.H. Frank,M.M., see Rosse,W.F. 611 430,447,462 449,460 Fromageot,c., see Prado,1.L. Fortwengler,H. P., Jr., see Fraser, P., see Verrinder,A 471,517 Poskitt, T.R. 432,459 581,587 Fruhman,G.J. 60,64 Fosdick, L. S., see Harris, S. C. Frederic, J., Ro bineaux, R. 113, FU,S.M., Kunkel,H.G., 602,611 131 Brusman,H.P., Allen,F.H., Fosdick,L.S., see Laden,C. Frederic,1., see Robineaux,R Jr., Fotino,M. 428,454 529, 533-536, 538, 540, 565 113,133 Fudenberg,H.H., see Boyle- Fosdick, L. S., see Sarkar, N. Freed,J.J., see Bhisey,A. N. Kay,M.M. 140,144,145, 546,566 124, 130 190 Author Index 679

Fudenberg,H.H., see Edelson, Furth,R., van, see Goud, Gallin,J., see Goldstein, 1. M. P.J. 124,131 T.J.L.M. 74,103 119,132,271,290,304,305, Fudenberg,H.H., see Huber,H. Furth,R., van, see Lai A Fat, 309 277,291,441,455 R.F.M. 76,104 Gallin,l.1., see Weiss,A.S. 472, Fudenberg;H.H., see Spitier,L. Furth,R., van see McClelland, 521 332,341 D.B.L. 73,76,104 Gallin,J.1., see Wright,D.G. Fujii, G., Suzuki, M., Hirose, Y., Furth, R., van, see Thompson, 301. 313 Goto, S., Ishibashi, Y., Haga, J. 79, 88-90, 107 Gammon,G.D., Starr, I.. Jr., K., Sindo, T. 449,454 Furth,R., van, see Waarde,D., Bronk,D.W. 531,563 Fujimoto, M. M., see Horowitz, van 84,93,94,96,107 Gander,G.W., Goodale,F. H.1. 139, 195 619,652 Gaarder,A., Laland,S. 150, Ganellin,C.R., see Black,l. W. Fuller, L.. Iglesias, E., Jensen, 193 14,19,333,337,354,366 1. A. 437,454 Gabbiani,G., Badonnel,M.C. Ganellin,C.R., see Brimble• Fullmer, H. M., see Lazarus. G. S. 36,41,64 combe,R.W. 355,366 302.310 Gabbiani,G., Badonnel,M.C., Ganellin,C.R., see Durant,G.J. Fullmer, H. M., see Robertson, Rona, G. 36,64 354,367 P. B. 280.293 Gabbiani, G., Badonnel, M .c., Ganeliin.C.R., see Parsons, Fulp,R., see Lim,R. K.S. 607, Majno,G. 38,64 M .E. 354.371 613 Gabbiani, G., Majno, G. 223, Garattini,S., Jori,A., Bernardi, Furlow,T.W., see Spector,A.A. 224,228 D., Carrara, c., Paglialunga, 182.202 Gabbiani, G., Majno,G., Ryan, S., Segre,D. 527, 528, 563 Furness, M.A., see Karat, A. B.A. G.B. 210,228 Garbe, G., see Friedberg, K. D. 244.262 Gabbiani,G., see Majno,G. 449.454 Furstenberg,A. C., see Blatt, 36,38,65 Garbe,G., see Vogt,W. 440, 1.M. 99.100 Gaddum,J.H., Guth,P.S. 473, 462 Furth, R., van 68, 89, 90, 102 510 Garcia Leme,J., Bohm,G.M., Furth,R., van, Cohn,Z.A. 74, Gaede,B.J., see Fried,J. 412, Migliorini, H., De Souza,Z.A. 79,84,102 417 552,563 Furth,R., van, Cohn,Z.A., Gaetano, G., de 153, 172, 193 Garcia Leme,J., Hamamura, L. Hirsch,l.G., Humphry,J.H., Gaffney,]., see Henney,c.S. 492,510,557,563 Spector, W. G., Langevoort, 358.368 Garcia Leme,J., Hamamura,L., H.L. 97,102 Gafni, Y., see Raz,A. 394, 400, Leite, M. P., Rocha e Silva, M. Furth,R., van, Diesselhoff-den 421 489,502,504,510 Dulk,M.M.C. 70,72,74, Gaither,T., see Leddy,J.P. Garcia Leme,J., Hamamura,L., 79,83,102 434,457 Migliorini,R.H., Leite,M.P. Furth, R., van, Diesselhoff-den Galanos,C., Rietschel,E.T., 487,510,552,563 Dulk,M.M.C., Mattie,H. Liideritz,O., Westphal,O., Garcia Leme,l., Hamamura,L., 79,82-84,86,102 Kim, Y. B., Watson,D. 618, Rocha e Silva,M. 475, 476, Furth,R., van, Fedorko,M.E. 652 482-485,497,502,510 83, 102 Galanos, C., see Liideritz, O. Garcia Leme,J.,Lica,M. 557, Furth,R., van,Gassmann,A.E., 618,653 563 Diesselhoff-den Dulk, Galatulas,1., see Ferri, S. 608, Garcia Leme,J., Rocha e Silva, M.M.C. 102 610 M. 475,501,510 Furth,R., van, Hirsch,J. G., Galdston,M., see Janoff,A. Garcia Leme,1., Schapoval, Fedorko,M.E. 72, 102 281,291 E. E. S. 540, 544, 546, 550, Furth,R., van, Langevoort,H.L. Galen 1,2 558,563 Schaberg,A. 92, 97, 102 Gall, E.A. 99, 102 Garcia Leme, J., Schapoval, E. Furth,R., van, Raeburn,J.A., Gall,E.A., see Braunstein,H. E.S., Rocha e Silva,M. 466, Zwet,T.L., van 72,76,102 99,100 467, 487, 489, 502, 504, 505, Furth. R.. van, Z wet, T. L., van Gall,E.P., see Boyer,J.T. 434, 510 Leyh, P. C.J. 76,102 451 Garcia Leme,1., Walaszek,E.1. Furth, R., van, see Blusse,A. 83, Gallily,R. 77,102 480,501,510 100 Gallin, J. 1., Quie, P. G. 136 Garcia Leme,J., see Hamma• Furth,R., van, see Crofton,R.A. Gallin,l.1., Rosenthal,A.S. mura,L. 571,585 79,82-84,86,100,101 124,125,131 Garcia Leme,J., see Rocha e Furth,R., van, see Gassmann, Gallin, J . 1., see Clark, R. A. F. Silva, M. 11, 17,24,500,501, A.E. 90,91,102 127,131,356,357,367 504,517.551,566,594,614 680 Author Index

Gardey-Levassort, e., see George, W. J., see Ignarro, L. J. Gielen, S. Y., see Homstra, G. Pel:U.R. 500.516 269, 291, 304, 305, 310, 556, 147,195 Gardner, D. L. 478, 498, 499, 564 Giertz, H., Hahn, F. 13, 15, 21 511 German,W.M. 98,103 Gigli, I., Austen, K. F. 427, 428, Gardner,E. 591,592,611 Gerrard,J.M., White,J.G., 437,438,454 Gardner,F.H., see Aas,K.A. Rao,G.N.R. 140, 155, 170, Gigli,1., Nelson,R.A. 426,441, 415 171,179,193 454 Garther, T., see Frank, M. M. Gerrard,J.M., White,J.G., Rao, Gigli,l., Nelson,R.A., Jr, 233, 427.449.453 G.N.R., Townsend.D. 193 261 Gartner,S., see Kaplan,H.S. Gerrard, J. M., see Glass, D. B. Gigli,1., Ruddy, S., Austen, K. F. 99, 104 160, 193 426.454 Garvin.J.E. 111.131 Gerschenfeld, H. M., Paupardin• Gigli,l., see Goetzl,E.J. 125, Gascon, L. A., see Rothschild, Tritsch,D. 361,368 131 A.M. 467,487,489,518 Gershon, M. D., Ross, L. L. Gigli,1., see Kempf,R.A. 438, Gassmann,A.E., Furth,R., 361,368 456 van 90,91, 102 Gershon,M.D., see Drakon• Gigli,1., see Koethe, S. M. 437, Gassmann,A.E., see Furth,R., tides, A. B. 361,367 456 van 102 Gershon, M. D., see Gershon, Gigli, I., see Kondo, M. 428, Gaugas,1. M., Billingham, R.K. 345,356,360,368 448,456 M.E.J., Rees,R.J.W. 529. Gershon, R. K., Askenase, P. W., Gigli,1., see Nelson,R.A. 433, 545,563 Gershon,M.D. 345, 356, 438.458 Gauldie, J., see Dolovich, J. 360,368 Gigli,l., see Ruddy,S. 271,293, 345,367 Gershon, R. K., see Schwartz, 439,460 Gautvik, K. M., Rugstad, H. D. A. 365.372 Gigli,1., see Soter, N .A. 449, 467.511 Gesner, B. M., Ginsburg, V. 461 Gear,1. S. S., see Alper, e. A. 101,131 Gilding,H.P., see Rous,P. 34, 430,441,442,450 Gesner,B.M., see Woodruff,J. 66 Gebauer-Fuelnegg, E., see 112.136 Gilfoil,T.M., Klavins,1. 490, Dragstedt,e.A. 13,20 Gewurz, H., Finstad,1., M uschel, 511.597.611 Gebest, H. J., see Rauterberg, I., Good,R.A. 437,454 Gilfoil, T. M., Klavins,1., E.W. 435,459 Gewurz, H., Pickering, R. J., Grumbach,L. 597,602,603, Gee,J.B.L., see Malawista, Christian, e. L., Snyderman, 611 S. E. 269,292 R., Mergenhagen, S. E., Good, Gillan,D.l., see Whitfield,J.F. Geiger, H., Day,N., Good,R.A. R.A. 427.454 497,521 434,454 Gewurz, H., Pickering, R. J., Gillespie,A. 598, 602, 603, 611 Geleick,H., see Polak,L. 250 Mergenhagen, S. E., Good, Gillespie, E. 304,308 264 R.A. 446,454 Gillespie, E., Lichtenstein, Gelfand,A., see Jaffe,C.J. 449, Gewurz,H., see Day,N.K.B. L. M. 349,368 456 437.452 Gillespie, E., see Lichtenstein, Gelfand, M.e., Shin, M. L., Gewurz,H., see McLeod,B. L. M. 350, 355, 357. 370 Frank,M.M., Nagle,R., 447. 457 Gillespie, E., see Plaut, M. 356, Green,1. 447,454 Gewurz, H., see Pickering, R. J. 357,359,371 426.459 Gillies,C.H. 526, 527, 563 Gell,P.G.H.,Hinde,I.T. 315, Gewurz,H., see Rent,R. 425, Gillis, M. H., see Koopman, W. 1. 338 460 324,339 Gell, P. G. H., see Benacerraf, B. Gewurz,H., see Snyderman,R. Gillis,M.H., see Koopman, 238,260 118. 134, 234,264, 440, 461 W. M. 358,369 Gell,P.G.H., see Coombs, Gewurz,H., see Stroud,R. M. Gillman,e.F., see Oss,C.l., van R.R.A. 283, 289, 345, 367 427.462 121. 135 Gemsa,D., Steggemann,L., Gey,K.F., see Pletscher,A. Gillman,T., Wright,L.J., 69, Menzel,J., Till,G. 305, 308 141.200 103 Gent,M., see Genton,E. 161, Ghetie, v., Mihaescu,S. 300, Gillson,R.E., see Bom,G.V.R. 193 308 141,190 Genton,E., Gent,M., Hirsh,J., Giacomelli,!., Wiener,]., Spiro, Gilman,A., see Goodman,L.S. Harper, L. A. 161,193 D. 36,64 225, 228. ~27, 564 George,M., Vaughan,J. H. Gianetto,R., see De Duve,e. Gilmore,N. Vane,l.R., Wyllie, 315,317,338 482.508 J.H. 152.193 Author Index 681

Gilmore,V., see Majno,G. 38, Gleich,G.J., Jacob,G.L. 347, Gotze,O., see Ruddy,S. 446, 65 368 460 Ginsburg, I. 273, 290 Gleich,G.J., see Solley,G.O. Gotze,O., see Schreiber,R.D. Ginsburg, I., Mitrani, S., 345,373 433,461 Ne'eman,N., Lahav,M. 87, Glenn,M.E. 551, 554,563 Gotze,O., see Vallota,E.H. 103 Glenn, M. E., Bowman, B. J., 430,462 Ginsburg,I., Trost,R. 255,261 Koslowske,T.C. 548,559, Goetzi,F.R., see Parsons,C.M. Ginsburg, V., see Gesner, B. M. 563 531,565 112,131 Glenn,M.E., Gray,J. 549,557, Goetzl, Austen, 137 Giordano,F., Scapagnini, U. 563 Goetzl,E.J., Austen,K.F. 125, 480,503,504,511 Glenn,M.E., Rohloff,N. 553, 131,436,440,454 Girault,J. M., see Kandasamy, B. 563 Goetzl,E.J., Wassermann,S.I., 621,631,633,634,653 Glenn,E. M., Wilks,J., Bowman, Gigli,I., Austen,K.F. 125, Girerd,R.J., see Di Pasquale,G. B. 181, 193 131 531,537,538,540,562 Glenn,E.P., Rohloff,N. 254, Goetzl,E.J., see Lewis,R.A. Girol,D., see Matthyssens,G.E. 262 348,350,363,370 359,370 Glossock,R.J., see Lerner,R.A. Goetzl,E.J., see Ruddy,S. 441, Giroud,J.P., Timsit,J. 536, 445,457 460 563 G1ovsky,M.M., Becker,E., Goetzl,E.J., see Valone,F.H. Giroud,J. P., Timsit,J., Spector, Halbrook,N.J. 448,454 173, 176, 203 W.G., WiIIoughby,D.A. Glovsky,M.M., Hugli,T.E., Goetzl, E. J., see Wasserman, S. I. 259,262 Ishizaka, T., Lichtenstein, 286,293,302,312 Giroud,J.P., WiIIoughby,D.A. L. M. 351, 368 Goetzl,F.R. 601,611 542,563 Glynn,L.E. 206,254,262 Goetzl,F.R., BurriII,D.Y., Giroud,J. P., Willoughby,D.A., G1ynn,L.E., Dumonde,D.C. Ivy,A.C. 589, 590,611 Velo,G. P. 260,262 210,228 Gold,M., see LaPierre,1.-G. Giroud, J. P., see Berry, H. 253, Glynn,L.E., Holborow,E.J. 364,370 255,260 256,262 Goldacre,R.J. 113,132 Giroud,J. P., see Capasso,F. Glynn,L.E., see Banerjee,S. Goldberg,N.D., Haddox,M.K, Nicol,S.E., Glass,D.B., 257,261 210,227 Giroud,J.P., see Di Rosa,M. Glynn,L.E., see Dumonde,D.C. Sanford,C.H., Kuehl,F.A., Jr. 488, 502, 503, 508, 527, 528, 252,254,261 Estensen,R. 354,368 Goldberg,N.D., see Estensen, 530,536,562 Glynn,L.E., see Fox,A. 255, R.D. 125,131 Giroud,J.P., see Velo,G.P. 261 Goldberg, N.D., see Hadden, 257,265 Glynn,L.E., see Pras,M. 221, J.W. 306,309,322,338 Gitlin,J.D., Rosen,F.S., Lach• 229 Goldberg,N.D., see Hill, H.E. mann,P.l. 428,454 Glynn,M.F., see Mustard,l.F. 356,357,369 Gjessing,R. 645,652 139,198 Goldberg,W.D., see Glass, Gocke,D.J., Hsu,K., Morgan, Glade,P.R., see B1oom,B.R. D.B. 160,193 c., Bombardieri,S., Lockshin, 320,337 Golde,D.W., Cline,M.J. 76, M., Christian, C. L. 242, 262 Glade, P.R., see Papageorgiou, 93,95,103 P.S. 320,340 Gocke,D.J., Osler,A.G. 442, Golde,D.W., Finley,T.N., Gladner,J.A. 482,511 454 Cline,M.J. 76,93,103 Gladner,J.A., Murtaugh, P. M., Godal, T., Rees, R. J. W., Goldfiner,S.E., see Melmon, Lamvik,J.O. 251,262 Folk,J.E., Laki,K. 482,511 K. L. 590, 594, 600,613 Godfrey,S. 351,368 Glass, D. B., Gerrard,J. M., Goldfinger,S.E., see Melmon, White,J.G., Goldberg,W.D. Godleski,J.G., Brain,J.D. K.L. 491,498,499,515 160,193 77, 103 Goldhamer,R.E., see Huber, Glass,D.B., see Goldberg,N.D. Gotze,O., Medicus,R., Miiller• W. 549,564 354,368 Eberhard,H.J. 454 Goldlust,M.B., Shin,H.S., Glatt,M., Kalin,H., Wagner,K., Gotze,O., Miiller-Eberhard, Hammer,C.H., Mayer,M.M. Brune, K. 76, 103 H.J. 429,434,435,454 433,434,454 Glatt, M., Peskar, B., Brune, K. Gotze,O., see Medicus,R.G. Goldlust,M.B., see Rommel, 179,193,530,563 429,431,458 F.A. 434,460 Glavenovich,J., see Bennett,J. Gotze,O., see Miiller-Eberhard, Goldman,A.S., see Grant,J.A. 382,416 H.J. 428,458 348,351,368 682 Author Index

Goldman,J.N., Ruddy,S., Good,R.H., see Stroud,R.M. Gordon,S., see Unkeiess,J.c. Austen, K.F. 434,455 427,462 281,293 Goldschmidt,R.P., see Taub• Goodale,F., see Gander,G.W. Gordon,S., see Werb,Z. 273, man,S.B. 301,312 619,652 280,281,294 Goldsmith,R., see Fox,R.H. Goodell,H., see Chapman,L. F. Gorman,R.R., see Fitzpatrick, 477, 510, 574, 585, 594, 611 29,63,492,507,594,595,609 F.A. 157,193 Goldstein, I. M., Brai, M., Osler, Goodell,H., see Hardy,J.D. Gorman,R.R., see Johnson, A.G., Weissmann,G. 271, 531, 533, 564, 591, 595-597, R.A. 196 290 611 Gorman,R.R., see Nishizawa, Goldstein, I. M., Hoffstein,S., Goodell,H., see Wolff,H.G. E.E. 157,175,199 Gallin,J., Weissmann,G. 601,605,616 Goth,A. 351,368 271,290,304,305,309 Goodman,J.W. 77,103 Goto,S., see Fujii,G. 449,454 Goldstein, I., Hoffstein, S., Goodman,L.S., Gilman,A. Goto,K., see Lim,R.K.S. 22, Hoffstein,S.y, Gallin,J., 225,228,527,564 481, 501,514, 589, 590, 600, Weissmann,G. 119,132 Goodwin,L.G., Jones,C.R., 603,612 Goldstein,I.M., Hoffstein,S., Richards, W.H.G., Kohn,J. Gotoff,S. P., see Bamzai,A. K. Weissmann,G. 269,290, 485,511 351,366 Goodwin,L.G., Richards, 304,309 Gotoff, S. P., see Lolekha, S. W.H.G. 492,511 Goldstein, I. M., Horn,1. K., 319,325,339 Gool,J., van, Ladiges,N.C.J.J. Kaplan,H.B., Weissmann,G. Gottert, H., see Rietschel, E. T. 546,567 268,290,298,309 618,654 Goldstein, I. M., Weissmann, G. Gool,]., van, Schreuder,l., Goud, T. J. I.. M. 93, 103 286,290, 301,309 Ladiges,N.C.J.J. 546,548, Goud, T. J. I.. M., Furth,R., van Goldstein,I.M., see Weissmann, 551,567 74, 103 G. 268, 270, 294, 306, 313 Gordon,A.H., see Billingham, Goldstein,S., Demeo,R., M.E.J. 538,545,547,548,561 Goud, T. J. 1. M., Schotte, c., Shemano,l., Beiler,]. M. Gordon,A.H., see Borges,D.R. Furth,R., van 74,103 528, 529, 531, 534, 538-54 Q 468,507 Gowans, J. 1.., see Marchesi, V. T. 555,563 Gordon,A.S., Neri,R.O., Siegel, 51,66 Goldstein,S., see Hitchens,1 .T. D. c., Dornfest, B. S., Handler, Gowdey,C. W., see Deneau, 527,531,532,534,541,564 E.S., Lobue,J., Eisler,M. G.A. 596,601,605,610 95, 103 Goldstein, T., see Weissman, G. Graeff,F.G., see Camargo, 18,25 Gordon,A.S., see Handler,E.S. A. C. M. 473,507 95, 103 Goldstone,A., Szabo, E., Graff,K.S., Leddy,J. P., Gordon,A.S., see Katz,R. 95, Koenig,H. 297,309 Breckenridge,R. T. 443,455 Golub, E .S., Spitznagel, J. K. 104 Gordon, D., Bray, M.A., Morley, Graham, J. A., see Peterson, B. H. 302,309 J. 324,334,338 434,459 Gomperts,B.D., see Foreman, Gordon,D., see Bray,M.A. Graham,J.R., Suby,H.I., J.D. 349,368 323, 333-336, 337, 554, 562 LeCompte,R.R., Sadowsky, Good,R.A., Thomas,L. 185, Gordon, D., see Morley,J. N. I.. 225,228 193,246,262 336, 340, 554, 559, 560, 565 Good,R.A., see Day,N.K.B. Graham,R.C., Erbert,R.H., Gordon,J.L. 141, 147, 156, 437,452 Ratnoff,O.D., Moses,1.M. 172,179,180,194 Good,R.A., see Fong,J.S.c. 474,477,482,511 Gordon,}. 1.., see Christian,F.A. 236, 246, 247, 261, 448, 453 Graham,R.C., see Moses,J.M. 148, 161,191 Good,R.A., see Geiger,H. 112,133 Gordon,J.L., see MacIntyre, 434,454 D.E. 153, 156, 158, 161, 163, Gramatica,L., see Anderson, Good,R.A., see Gewurz,H. 197 M. C. 499,506 427,437,446,454 Gordon,J.M., see Colten,H.R. Granger,G.A. 330,333,338 Good,R.A., see Moncada,B. 452 Granger,G.A., Williams,T. 426,458 Gordon,S. 73,76,103 279,281,290 Good,R.A., see Park,B.H. Gordon,S., Cohn,Z.A. 72, 76, Granger,G.A., see Kolb, W. P. 305,311 103 319,332,339 Good, R. A., see Pickering,R.1. Gordon,S., Todd,J., Cohn,Z.A. 426,459 282,290 Granger,G.A., see Williams, Good,R.A., see Stetson, C.A., Jr. Gordon,S., Unkeless,J.C., T.1. 330,341 246,264 Cohn,Z.A. 274,281,290 Granstrom, E. 394, 395,417 Author Index 683

Granstrom, E., see Samuelsson, Greenbaum, L., see Eisen, V. Gross,J., see Kang,A.H. 209, B. 394,421,405,408,421 502,509 228,302,310 Grant,J. A., Dupree, E., Gold• Greenbaum,L.M. 286,290, Gross,J., see Piez,K. 216, 229 man,A.S., Schultz,D.K., 299-301,309 Grosshans, E., see Hauptmann, Jackson,A.L. 348,351,368 Greenbaum, L. M., Freer, R., G. 427,455 Grant,J.A., Lichtenstein,L. M. Chang,J., Semente,G., Grossmann,R.J., see Hirsch• 347,351,368 Yamafuji,K. 495,496, 5ff horn,R. 306,310 Grant,J.A, see Thueson,D.O. Grotte,G. 33,64,583,585 Greenbaum,L. M., Grebow, P., 351,373 Griitzmacher,J., see Friedberg, Johnston, M., Prakash, A, Grant, L. H., Palmer, P., Sanders, K.D. 449,454 Semente,G. 309 AG. 28,64 Grumbach, L., see Gilfoil, T. M. Grant, L. H., see Florey, H. W. Greenbaum,L.M., Kim,K.S. 597,602,603,611 49,63,111,114,131 473,495,511 Grundfest, H., see Sherman, H. Grant,M.E., Prockop,D.J. Greenbaum, L. M., Yamafuji, K. 601,602,614 211,228 300,309,473,495,511 Grundmann, M. J. 640, 652 Grant,R., Adler,R.D. 630,652 Greenbaum, L. M., Yamafuji, K., Gryglewski, R. J., Bunting, S., Grant,R.A., see Zucker,M.B. Kim, K. S. '495,511 Moncada, S., Flower, R. J., 161,205,443,463 Greenbaum, L. M., see Chang,J. Vane,J.R. 142,158,175,194 Grant,R.T., Wood,J.E. 54,64 286,289 Gryglewski,R.J., Panczenko,B., Grant,R.T., see Lewis,T. 13, Greenbaum, L. M., see Engle• Korbut,R., Grodzinska,L., 22,28,65,574,586 man, E. G. 496, 509 Ocetkiewicz,A 178, 194 Gray,J., see Glenn,M.E. 549 Greene, J. L., see Sampaio, Gryglewski, R.J., Szczeklik,A., 557,563 M.U. 465,518 Bieron,K. 168,172,194 Gray, L., see Kaplan,A. P. 352, Greene, L. J., Camargo, A. C. M., Gryglewski,R., Vane,J.R. 157, 361,369 Krieger,E.M., Stewart,J.M., 194,392,417,601,611 Greaves,M., Schuster,S. 476, Ferreira,S.H. 488,5ff Gryglewski,R., see Flower,R.J. 511 Greene, L. J., see Camargo, 153, 193 Greaves, M. W., McDonald• A C. M. 466,473,507 Guccione, M. A., Packham, Gibson, W. 599,611 Greengard, P., see Delorenzo, M.A., Kinlough-Rathbone, Greaves, M. W., S"mdergaard, R. J. 306, 308 R.L., Mustard,1.F. 150,194 J.S. 572,585,606,611 Greenwood, B. M., Whittle, Gugler,E., Liischer,E.F. 165, Grebow, P., see Greenbaum, H.C., Bryceson,AD.M. 194 L.M. 309 244,262 Guimares, J. A, Borges, D. R., Green, 1., see Benacerraf, B. Greenwood, B. M., see Whittle, Prado,E.S., Prado,J.L. 466, 238,260 H. C. 244, 265 5ff Green,1., see Ellman, L. 453 Greff, K., Liihr, R., Strobach, H. Guimares,J.A., Chen-Lu,R., Green, 1., see Gelfand, M. C. 467,469,499,511 Webster,M.E., Pierce,J.V. 447,454 Greineder,D.K., see Rosenthal, 466,5ff A.S. 77,106 Guimaraes,J. A., see Borges, Green, 1., see Shevach, E. M. Greisman,S.E., Woodward, D.R. 466,507 277,293 C. L. 619,652 Guimaraes,J.A, see Webster, Green,J.A, Cooperbrand,J.S., Grette,K. 145,194 M.E. 466,472,520 Rutstein,J.A, Kibrick,S. Grey,H.M. 437,455 Gunnar,R.M., Weeks,R.E. 319,330,338 Grey,H.M., see Ross,G.D. 504,511 Green,J.P., Johnson,C.L., 441,460 Gunstone, F. D., see Downing, Weinstein, H., Maayani,S. Gribik,M., see Salvin,S.B. D.T. 414,417 361,368 324, 341 Gupta, K. P., see Dey, P. K. Green,J. P., Maayani,S. 361, Griffin,F.M., Bianco,C., Silver• 621, 638, 640, 642-644, 646, 368 stein,S.C. 73, 103, 442, 455 651 Green, K., Bygdeman, M., Griffin, F. M., Silverstein, S. C. Gupta, K. P., see Feldberg, W. Toppozada,M., Wiqvist,N. 115,132 621,637,638,641,644,651 402,417 Griffin,F. M., see Bianco, C. Gurewich, V., see Ream, V. J. Green,K., Samuelsson,B. 403, 73, 100,442,451 184,200 408,417 Grijsen, H., see Bonta, 1. L. Guth,P.S., see Back,N. 494, Green,K., see Samuelsson,B. 551,562 506 402,405,408,421 Grodzinska,L., see Gryglewski, Guth,P.S., see Gaddum,J.H. Green, K. L. 540, 555, 556, 564 R.J. 178, 194 473,510 684 Author Index

Guttmann,S., see Boissonas, Hadding, U., see Bentley,C. Ham,E.A., see Kuehl,F.A. R.A. 16,20,464,474,506,507 429,450 554,565 Gutmann,S., see Pless,J. 464, Hadding, U., see Brade, V. 429, Ham, K. N., Hurley,J. V. 516 451 41-43,64 Guy,J.1., see Davison,C. 607, Hadding, U., see Burger,R. Ham,K.N., see HurJey,1.V. 610 279,289,432,447,451 38,42,46,64 Guzman,F., Braun,C., Lim, Hadding, U., see Nicholson,A. Hamamura, 1., see Garcia Leme, R.K.S. 481,511,589-591, 431,433,458 J. 475,482-485,487,489, 593, 594, 596, 597, 599, 602, Haddox, M. K., see Goldberg, 492, 497, 502, 504, 510, 552, 605,611 N.D. 354,368 557,563,571,585 Guzman,F., Braun,C., Lim, Haddox, M. K.,seeHadden,J. W. Hamada,M., see Umezawa,H. R.K.S., Potter,G.D., 306,309,322,338 300,312 Rodgers,D.W. 16,17,21, Haeckel,E. 68,103 Hamberg,M. 377,400,403, 501,511,603,611 Haga,K., see Fujii,G. 449,454 404,417 Guzman,F., see Dickerson, Hagen,J.J., see Ablondi,F.B. Hamberg,M., Hedqvist,P., G.D. 591,610 449,450 Strandberg, K., Svensson,J., Guzman,F., see Lim,RK.S. Hahn, F., Oberdorf, A. 13, 2 j Samuelsson,B. 601,611 16,22,481,501,514,589,590, Hahn,F., see Giertz,H. 13, 15, Hamberg, M., Jonsson, C. E. 592, 594, 596, 600, 603, 607, 21 403,418 612,613 Hahn,H., see Wagner,W.H. Hamberg, M., Samuelsson, B. Guzman,F., see Potter,G.D. 68,107 141,146,154,158-160,168, 593,614 Haines,A.1., Lepow,1. H. 426, 172,176,194,386-388,390, 455 391,393,394,402-406,408, Habal, F. M., Burrowes, C. E., Haining, C. 1. 533, 564 414,418 Movat,H.Z. 471,511 Hakim,A.A., Dailey,J. P., Lesh, Hamberg, M., Samuelsson, B., Habal,F.M., Movat,H.Z., 1: B. 546, 564 Bjorkhem,1., Danielsson, H. Burrowes,C.E. 466,470,511 Halbrook,N.J., see Glovsky,M. 406,418 Haber, E., see Meyers, 0.1. M. 448,454 Hamberg,M., Svensson,J., 331,339 Hales,1.R.S., Bennett,J.W., Samuelsson,B. 146,154, Haber, E., see Remold, H. G. Baird,J.A., Fawcett,A.A. 156-159, 164, 168, 169, 172, 331,340 625,629,652 181,194,387,388,390-392, Haberland,G.1., Rohen,J. W. Hales,J.R.S., see Baird,J.A. 404,418 469,511 623,626,627,629;649 Hamberg,M., Svensson,J., Habermann,E. 466-468,512 Hall,J. G., Morris, B., Wooley,G. Wakabayashi, T., Samuels son, Habermann,E., B1ennemann,G. 59,64 B. 154, 156, 158, 160, 164, 465,469,512 Hall,J.G., see Moore,A.R. 181,194,386,387,418 Habermann,E., Blennemann, G., 128,133 Hamberg, M., see Hammar• MUlier, B. 466, 512 Hall, 1. M., see Benitz, K. F. strom,S. 375,405,418 Habermann, E., Helbig,1. 466, 275,288 Hamberg, M., see Malmsten, C. 512 Hall,R.C., Hodge,R.1., Irvine, 146, 157, 166, 168, 171, 172, R., Katic,F., Middleton,J.M. Habermann,E., Klett,W. 469, 197, 406, 419 512 185, 194 Hamberg, M., see Needleman, P. Hall,RE., CoJten,H.R. 427, Habermann,E., MUller,B. 471, 15~ 157, 199,601,613 455 512 Hamberg, M., see Nishizawa, Hall,R.E., see Brade, V. 429, Habermann, E., see Urbanitz,D. E.E. 157,175,199 467,520 451 Hamberg, M., see Samuelsson, B. Habib, R, Loirat, c., McBugler, Hall, W. F., see Clegg, P. C. 604, 388,394,405,408,421 M., Levy,M. 447,455 605,609 Hadden,E. M., see Hadden,J. W. Haller,A. von 2 Hamberg, M., see Strandberg, K. 404,422 306,309,319,322,338,339 Halmagyi, D. F. J., see Margolis, Hamberg,M., see Svensson,J. Hadden, J. W., Hadden, E. M., J. 467,515 Haddox, M. K., Goldberg, Halpern,B.N. 14,21 157,202,601,615 Hamberg, U. 465,471,512 N.D. 306,309,322,338 Halushka, P. V., Weiser, c., Hadden,J. W., Sadlick,1.R., Chambers, A., Colwell,J. Hamberg, U., Elg, P., Nissingen, Hadden,E. M. 319,339 159, 194 E., Stelwagen, P. 467,512 Hadding, U., MUlier-Eberhard, Halvorsen,K., see Fasciolo,J.C. Hamberg, U., Rocha e Silva, M. H. 1. 434,455 467,509 465,473,512 Author Index 685

Hameran,D., see Barland,P. Hardman,J.G., see Broadus, Harvey,C.A., see Milton,A.S. 284,288 A. E. 305, 308 621,633,653 Hamerman,D., see Schubert,M. Hardy,J.D., Stolwijk,J.A.J., Harvey,E.A., see Ferreira,S.H. 216,230 Hoffman,D. 591,611 600,602, 610 Hamerman,D., see Smith,C. Hardy,J.D., WolfI,H.G., Harvey,E.A, see Flower,R.J. 299,312 Goodell,H. 531,533,564, 173,193,375,417,577,585 Hamilton,E.B.D., see 591,595-597,611 Harvey,E.A., see Ubatuba,F.B. McArthur,J. N. 558,565 Hardy,J.D., see Andersen,H.T. 181-183,203 Hamilton, E. D. B., see Swinson, 630,649 Harvey,R.L., see Holley, T.R. D.R. 179,202 Hardy,J.D., see Cabanac,M. 126,132 Hammarstrom,S., Hamberg, M., 630,650 Harzer, K., see SandhofI, K. 98, Samue\sson, B., Duell, E. A., Hardy,J.D., see Stitt,J.T. 625, 106 Stawiski,M., Voorhees,J.J. 628--630,655 Hashimoto, K., Kumakura, S., 375,405,418 Hardy,J.D., see WolfI,H.G. Taira;N. 594,611 Hammel, H. T., see Andersen, 601,605,616 Haslam,R.J. 151,194 H. T. 630,649 Hargreave, F. E., see Dolovich, J. Haslam,R.J., McClenaghan, Hammel, H. T., see Sharp, F. R. 345,367 M.D. 150,160,194 630,654 Harington, J. C., see Allison, A. C. Hassam, A. G., see Rivers,J. P. W. Hammer, C. H., Abramovitz, 272,277,288 172,201 A. S., Mayer, M. M. 433,434, Harker, L. A., Slichter,S.J. Hassid,W.Z., see Neufeld,E.F. 455 164, 194 215,229 Hammer,C.H., Nicholson,A., Harpel,P.C. 436,455,469, Hastie, R. 348, 368 Mayer, M. M. 435,455 470,512 Haswell,A.D., see Davies,P. Hammer,C.H., see Goldlust, Harpel,P.C., Cooper,N.R. 270,289 M.B. 433,434,454 436,455 Hathway, W.E., Belhasen,L.P., Hammerman, D., see Barland, P. Harper, E., see Chesney, C. M. Hathway,H.S. 472,512 299,307 179,191 Hathway,W.E., see Belhasen, Hammond,A.R., see Collier,H. Harper, L.A., see Genton,E. L.P. 472,512 O.J. 609 161,193 Hathway,H.S., see Hathway, Hammond,E., see Dvorak,A. Harper,M.J.K., see Scarnes, H.S. 472, 51~ M. 324,338 R.C. 412,421 Haugertam,G., see Olgart,L. Hamon,B., see Klebanoff,S.J. Harpman,J.A, Whitehead,T.P. 605,613 76,104 595,611 Haupt,!., see Fischer,H. 111, Handler,E.S., Varsa,E.E., Harris, E. D., Jr., Dibona, D. R., 131 Gordon,A.S. 95,103 Krane,S. M. 446,455 Hauptmann, G., Grosshans, E., Handler,E.S., see Gordon,A.S. Harris,E.D., Jr., Reynolds,J.J., Heid,E. 427,455 95,103 Werb,Z. 281,291 Hausman,M.S., see Snyderman, Handwerker,H.O. 600,611 Harris,H., see Ramsey, W.S. R. 118,134 Hansen,G., see Stanley,E.R. 114,133 Hawiger,J., Collins,R.D., Horn, 95,107 Harris,J.M., West,G.B. 580, R.G. 303,309 Hansen,H.S. 413,418 585 Hawkey,C., see Press,M. 168, Hansen, P.J., see Einstein,L. P. Harris,S. c., Fosdick,L.S. 172,200 429,453 602,611 Hawkins,D. 270,271,291, Hanson,J.H., see Franco,M. HartIey,R.E., Davies,H.T.S., 303,304,309 328,338 Schild,H.O. 571,586 Hawkins,D., Peeters,S. 268, Hanson,J.M., see Bray,M.A Hartmann, K. U., Bokisch, V. A. 270,271,291 320,325,327,332,333,337 442,455 Hawkins,D.,seeCochrane,C.G. Hapel, A. J., see Blanden, R. V. Hartop,J.P., see Press,M. 168, 243,261 76,100 172,200 Hawthorne,G.A, see Ballan• Harada,Y., see Hori,T. 624, Hartwig,J. H., Stossel, T. P. tyne,D.L., Jr. 188,189 625,628,630,652 124,132 Hay,J. B., see Trnka,Z. 239, Hardingham,T.E., Muir,H. Hartwig,J. H., see Stossel, T. P. 265 209,228 124,125,134 Hayashi, H., Yoshinaga, M., Hardingham, T. E., see Wiebkin, Harvey, C. A, Milton, A S. Koono,M., Miyoshi,H., O. W. 209,230 633,641,652 Matsumura,M. 537,564 Hardisty,R.M., Hutton,R.A Harvey,C.A, Milton,AS., Hayashi, H., Yoshinaga, M., 139, 162, 167, 194 Straughan, D. W. 638,652 Yamamoto,S. 120, 132 686 Author Index

Hayashi,H., see Ichikawa,A. Henney,c.S., Gaffney,J., Bloom, Hernandovich,J., see Kocsis, 554,564 B.R. 358,368 J.J. 153, 173, 179, 196, 401, Hayashi,O., see Miyamoto, T. Henney,C.S., see Bourne,H.R. 419 382,394,419 345, 350, 366 Herrin,J.T., see Einstein,L. P. Haye,B., Champion,S., Jac• Henney,C.S., see Plaut,M. 428,453 quemin,C. 377,380,418 356, 357, 359,371 Herring, W. B., Herion,J. C., Hayes,J.R., see Rooney,P.J. Henriques, 0. B., Fichman, M., Walker,R.I., Palmer,J.G. 544,566 Beraldo,W.T. 465,512 185,195 Hazelhof,E., see Nugteren,D.H. Henriquez,F.C. 591,611 Hers,H.G. 98,103 154,199,386,388,420 Henriquez,F.C., see Moritz, Hers,H.G., see De Duve,C. Heather,C.J., see Katz,S.1. A.R. 591,613 295,308 250,263 Henriques, 0. B., Kauritchewa, Herxheimer, H., Streseman, E. Heaysman,J.E.M., see Aber- N., Kuznetsova, V., Astrakan, 499,512 crombie,M. 114,129 M. 466,469,512 Herzog, P., see Ehringer, H. 17, Hebborn, P., Shaw,B. 502,512 Henriques,O.B., Lavras,A.A. 20,477,508 Hedberg,A. 445,446,455 c., Fichman, M., Picarelli, Hess, W., see Lewis, T. 595, Hedqvist, P. 605,611 Z.P. 465,469,512 612 Hedqvist, P., see Hamberg, M. Henry,E.,seeClark,W.G. 636, Hesse,E., Roesler,G., BUhler,F. 601,611 643,650 589,597,602,611 Heesom,N., see Spector, W.G. Henson, P. M. 184, 194, 233, Hester,R.B., see Hurst,M.M. 232,251,264,277,293 262,268,270,271,291,299, 426,456 Heid,E., see Hauptmann,G. 303,309,345,348,368,442, Heusser, c., see Knobel,H.R. 427,455 455 426,456 Heilman,D.H., see McFarland, Henson, P. M., Cochrane, Hibbs,J.B., see Remington,J.S. W. 115,132 C.G. 182-184,195,243,262, 77,106 Heimberg,M., see Danon,A. 443,444,455 Hicks,R. 529,564 380,416 Henson, P. M., Johnson, H. B., Hicks,R., see Atkinson,D.C. Helbig,J., see Habermann,E. Spiegelberg,H.L. 270,271, 527,537-541,555,556,561 466,512 291 Higgs,G.A., McCall,E., Youl• Hellem,A.J. 147,194 Henson,P.M.,Oades,Z.G. ten,L.J.T. 175,195 Hellman, W., see Rosenberg,L. 270,291,304,309 215,229 Highton,T.C. 531,538,545, Henson,P.M., see Hecker,E.L. 564 Hellon,R.F. 632,649,652 119,130,271,272,288,348, Hellon,R.F., see Cranston,W.1. Hilgartner, M. W., see Zucker, 349,366 M.B. 166,205 621,632,640,648,649,650 Henson, P. M., see Deshazo, Hill,E.G., see Dahle,I.K. 388, Helminen,H.J., Ericsson,J.L.E. C. V. 299,308 297,309 416 Henson,P.M., see Shazo,C. V. Helmont, van 2 Hill, H. R., Estensen, R. D., de 444,452 Helvey, W. M., see Benjamin, Quie,P.G., Hogan,N.A., Hepburn,B., see Crout,J.E. F. B. 593, 609 Goldberg,N.D. 356,357, 333,337 Hembry,R.M., see Poole,A.R. 369 Hepper,N.G.G., see Hunder, 283,292 Hill,H.R., see Estensen,R.D. G.G. 456 Hempel, K. H., Fernandez, L. A., 125,131 Hepplestone,A.G. 98,103 Persellin,R. H. 551,564 Hill, H. U., see Raepple, E. 448, Herbaczynska-Cedro, K., see Hench, P. S. 550,564 449,459 Hench, P. S., Kendall, E. C., Flower,R.J. 153,193 Hill,J.A., see Ward,P.A. 286, Slocumb,C.H., Polley,H.F. Herion,J.C., Spitznagel,J. K., 293 550,564 Walker, R. I., Zeya, H. I. Hill,J.C., see Ward,P.A. 301, Hendricks, C. H., Brenner, W. E., 303,309 312 Ekbladh,L., Brotanek, V., Herion,J.C., see Herring,W.B. Hill,J.H., see Ward,P.A. 234, Fisburne,J.1. 625,652 185,195 265 Hendrickse,R.G., see Allison, Herion,J.C., see Saba,H. 303, Hilton,S.M. 477,512 A. C. 244, 260 311 Hilton,S.M., Lewis,G.P. 469, Henley, W. L., see Papageorgiou, Herman,A.G. 186,195 512 P.S. 320,340 Herman,A.G., Moncada,S. Hinde,I.T., see Gell,P.G.H. Henney,C.S., Bourne,H.R., 186,195,600,605,611 315,338 Lehrer, R. I., Cline, M. J., Mel• Hermina, M., see Tsung, P.-K. Hinshaw,L. B., Jordon, M. M., mon, K. L. 305, 306, 309 306,312 Vick,J.A. 184,195 Author Index 687

Hinshaw,L.B., see Solomon, Hoffmann,G., see Meuret,G. Holmsen,H., Setowsky,C.A., L.A. 185,202 83,86,105 Lages,B. 170,195 Hinz,C.F., Jr., see Pensky,J. Hoffmeister,F., see Kaller,H. Holmsen, H., Weiss,H.J. 195 459 502,513 Holmsen,H., see Day,H.J. Hirose, Y.,seeFujii,G. 449,454 Hoffstein, S., Weissmann, G. 141, 145, 151, 160, 164, 168, Hirsch,J., see Baggiolini, M. 272,291,553,556,567 170,173,176,192 296,307 Hoffstein,S., see Goldstein,1. Holmsen,M., Weiss,H.J. 169, Hirsch,J.G. 184,195 119,132 195 Hirsch,J.G., Cohn,Z.A. 61,64 Hoffstein,S., see Goldstein,I.M. Holton,F.A., Holton,P. 574, Hirsch,J.G., see Baggiolini,M. 269,271,290,304,305,309 586 268,288 Hoffstein,S., see Weissman,G. Holton,P., see Holton,F.A. Hirsch,J.G., see Cohn,Z.A. 18,25,303,304,306,313,553, 574,586 18,20,234,261,297,308 556,567 Holtzer,H., see Ishikawa,H. Hirsch,J.G., see Furth,R. van Hoffstein,S., see Zurier,R.B. 269,291 72,97,102 270,272,294,303-305,313, Honda, Y., see Ishioka, T. 550, Hirsch,J.G., see Zigmond,S.H. 356,357,373,553,567 564 Hong,S.-c.L., Levine,L. 412, 113,116,117,124,136,269,294 Hogan,G.P., see Matthew,T.H. 418 Hirschel,B.S., see Majno,G. 188,198 Hogan,N., see Estensen,R.D. Hong,S.L., Levine,L. 178,195 36,38,65 125,131 Honour,A.J., see Cooper,K.E. Hirschhorn,R. 172,195 Hogan,N.A., see Hill,H.R. 620,646,650 Hirschhorn, R., Grossmann, R. 356,357,369 Hook,E.E., see Horowitz,H.1. J., Weissman,G. 306,310 Holborow,E.J., see Glynn,L.E. 184, 185, 195 Hirsh,J., see Genton,E. 161, 256,262 Hook,E. W., Jr., see DesPrez, 193 Holdstock,D.J., Mathias,A.P., R.M. 184,185,192 Hirshfield,M., see Marsland,D. Schachter, M. 574, 585 Hook,W.A., Schiffman,E., 304,311 Holenberg, M. J., see Thai, A. P. Aswanikumar,S., Siraganian, Hitchens,J. T., Goldstein,S., 499,519 R. P. 348,351,369 Shemano,l., Beiler,J. M. Holgate,J.A., see Collier,H.O. Hook, W. A., Siraganian, R. P., 527,531,532,534,541,564 J. 499,501,508 Wahl,S.M. 348,351,369 Hitchens, M. 333,339 Hollander,J.L., see McCarty, Hook,W.A., see Siraganian,R. Hladovec,J., Mansfeld, V., D.J. 303,311 P. 351,372 Honikovli,Z. 502,512 Hollenberg, M.D., see Cuatre• Hooks,J.J., see Ida,S. 351,369 Ho,I.K.,Loh,H.H.,Leong,Wav, casas, P. 346,367 Horakova,Z., Muratova,J. E. 608,611 Holley,T.R., Epps,D:Evan, 528, 530, 532, 534, 540, 555, Hoak,J.C., see Spector,A.A. Harvey,R.L., Anderson,R.E., 564 182, 202 Williams,R.C. 126,132 Horakova,Z., see Hladovec,J. Hobart,K.J., Alper,C.A., Lach• Holm, G., see Huber,H. 73,103 502,512 mann,P.J. 434,455 Holman,G., see Davies,G.E. Horakowa,Z., see Kaplan,A.P. Hobbs,J.B. 187,195 502,504,508 352,361,369 Hori,S. 473,512 Hoch, W.S., see Spector,A.A. Holman,R.T., see Dahle,I.K. Hori,T., Harada,Y. 624,625, 182,202 388,416 628,630,652 Hochberg,R., see Innerfie1d,I. Holman, R. T., see Marcel, Y. L. Hori, T., see Nakayama, T. 503,513 380,419 Holmes, B., see Estensen,R. D. 630,654 Hochstrasser,K., Werle,E. 268,290,298,308 Horiuchi,K., see Suzuki,T. 466,512 Holmes,S. W. 637,643,652 465,466,469,519 Hodge,A.G., Schmitt,F.O. Holmes,S. W., Horton,E. W. Horiuchi,K.,seeYano,M. 466, 218,228 469,522 Hodge,A.J., Petruska,J., Bailey, 644,652 Holmes,T.H., see Dorpat,T.L. Horn,J.K., see Goldstein,I.M. A.J. 218,228 593,610 268,290,298,309 Hodge,R.L., see Hall,R.C. Holmsen,H. 140, 141, 146, 195 Horn,R.G., see Hawiger,J. 185,194 Holmsen,H., Day,H.J. 272, 303,309 Hoefsmit, E. C. M., see Beelen, 291 Horner,G.J., see Margolis,J. R.H.J. 73,100 Holmsen, H., Day,H.J., Storm, 467,515 Hoffer,B., see Siggins,G. 607, E. 141,160,164,195 Hornstra,G., Gielen,S. Y. 147, 614 Holmsen,H., Day,H.J., 195 Hoffman,D., see Hardy,J.D. Stormorken,H. 141, 146, Horowitz,H.I., Des Prez,R.M., 591,611 160, 164, 195 Hook,E.E. 184,185,195 688 Author Index

Horowitz, H. I., Fujimoto, M. M. Huber, H., Wagner,M. 277, Hureau,J., Forlot, P., Raby,e., 139,195 291 Vairel,E. 499,513 Horowitz,H.I., see Des Prez,R. Huber,W., Schulte,T.L., Hurley,1. V. 26, 38, 46, 53-55, M. 184, 185, 192 Carson, S., Goldhamer,R. E., 64,109,129,132 Hortega, P. De Rio X. 647,652 Vogin,E.E. 549,564 Hurley, J. V., Edwards,B. 29, Horton,E., see Elliot,D.F. Hudack,S., McMaster, P. D. 42,64 474,477,480,509 59,64 Hurley,J.V., Edwards,B., Ham, Horton,E.W. 17,21,383,418, Hugl, E. H., see Rothstein, G. K.N. 38,64 473,513,598,612,644,653 95,106 Horton,E. W., Jones,R.L. Huggins,e.G., see Sander,G.E. Hurley,J.V., Ham,K.N., Ryan, 409,418 465,518 G.B. 42,46,64 Horton,E. W., Jones,R.L., Hughes, R. e., see Kessler, E. Hurley,1. V.,Jago,M. 42,46,64 Marr,G.G. 400,418 412,418 Hurley,J.V., McCallum,N.E. Horton,E. W., see Elliot,D. F. Hugli, T. E., Morgan, W. T., W. 34,64 16,21,464,509,574,585 Muller-Eberhard, H. J. Hurley,1. V., McQueen,A. 38, Horton, E. W., see Holmes, S. W. 429,455 42,64 644,652 Hugli,T.E., see Glovsky,M.M. Hurley,J. V., Ryan, G. B. 47,64 Horton,J.E., Raisz, L. G., 351,368 Hurley,J. V., Spector, W. G. Simmons, H. A., Oppenheim, H ugJi, T. E., see Johnson, A. R. 43,46,54,65 J.J., Mergenhagen,S.E. 319, 440,456 Hurley,J. V., Willoughby, D.A. 330,339 Hugli,T.E., see Mahler,F. Horwood-Barrett, S., see Collier, 440,457 46,65 H.O.J. 609 Hugo,R., see Vinegar,R. 527, Hurley,J. V., Xeros, N. 51,65 Houba, V., see Allison,A. C. 567 Hurley,J. V., see Cunningham, 244,260 Hulliger, P. L., Blazkovec, A. A., A. L. 38,42,63 Houck,J., Chang,e. 120,132 Sorkin, E. 251,262 Hurley,J.V., see Ham,K.N. Houck,J. e. 207,228 Hulsing-Hesselink,E., see 41-43,64 Houck,J.e.,seeChang,e. 120, Waarde,D. van 84,93,94, Hurley,J.V., see McQueen,A. 131 96, 107 54,65 Hougie,C., see Baugh,R. 163, Humes,J.L., see Davies,P. Hurley,1. V., see Ryan,G.B. 189 101 47,66,129,134 Hovig, T. 139,195 Humes,J.L., see Kuehl,F.A. Hurlimann,J., see Rother, U. Hovig,T., see Day,H.J. 141, 554,565 434,460 Hummel,F. P., see Ungar,G. 192 Hurst,M.M., Volanakis,J.E., Howard,A., see Temple,A. 502,520 Hester,R.B., Stroud,R.M., Humphrey,J.H. 233,240, 270,293 Bennett,J.C. 426,456 262,299,310 Howard,J.G. 77,103 Hurwitz,E., see Matthyssens, Humphrey,J. H., Dourmashkin, Howard,J. G., see Rowley, D. G. E. 359,370 R.R. 233,262,435,456 Huskisson,E.e., see Dieppe, 621,654 Humphry,J.H., see Furth,R. van P.A. 258,259,261 Howard,J.M., see Satake,K. 97,102 499,518 H uskisson, E. e., see Yamamoto, Hunder,G.G., Mcduffie,F.C., S. 257,265 Howard,M.A., Firkin,B.G. Hepper,N.G.G. 456 Hutton, J. J., Jr., Tappel,A.L., 166,195 Hunder,G.G., Muller,B.J., Udenfriend,S. 220, 228 Howson, W. T., see Dumonde, Mcduffie, F. C. 446,456 Hutton, R. A., see Hardisty, R. M. D.e. 317,321,338 Hunsicker,L.G., Ruddy,S., 139, 162, 167, 194 Hsia, S. L., Ziboh, V. A., Snyder, Austen,K.F. 456 Hylotar, W. J., see Davies, P. D.S. 606,612 Hunsicker,L.G., Ruddy,S., 301,308 Hsu,K., see Gocke,D.J. 242, Carpenter, e. B., Schur, P. H., 262 Merrill,1. P., Muller-Eber• Iacono,J.M., see Shoene,N.W. Hsu,L.S., see Becker, E. L. hard, H. J., Austen, K. F. 159,170,178,201 119,/30,271,288 446,447,456 Ichikawa,A., Nagasaki, M., Huber, H., Holm,G. 73,103 Hunt,H.R., see Pounder,R.E. Umezu,K., Hayashi, H., To• Huber,H., Polley,M.J., 355,371 mita, K. 554,564 Linscott, W. D., Fudenberg, Hunter,1. 2, 3, 7, 2 I, 231, 262 Ida,S., Hooks,J.J., Sira• H. M., Muller-Eberhard, Hurd,E.R., see Cooke,T.D. ganian, R. P., N otkins, A. L. H.J. 277,291,441,455 285,289 351,369 Author Index 689

Iggo,A. 591,612 Ishibashi, T., see Mackaness, Jacob,G.L., see Gleich,G.J. Iggo,A., see Fjallebrant,N. G.B. 76,105 347,368 592,610 Ishibashi, Y., see Fujii,G. 449, Jacob,J., see Kandasamy,B. Iglesias, E., see Fuller,L. 454 621,631,633,634,653 Ishikawa,H., BischotI,R., 437,454 Jacobs,H.J., see Baile,C.A. Ignarro,L., see Oronsky,A. Holtzer,H. 269,291 626,627,649 Ishikawa,H., Smiley,J.D., 292 Jacobsberg,M., see Downing, Ignarro,L.J. 286,291,304,310 ZitI, M. 285,291 D.T. 414,417 Ishioka, T., Honda, Y., Sagara, Ignarro,L.J., Columbo,C. Jacobsen,S. 466,469,473,486, A., Shimamoto,T. 550,564 306,310 513 Ishizaka, K., Ishizaka, T. 346, Ignarro,L.J., George, W.J. Kriz,M. 466,513 347,369 Jacobsen,S., 269,291,305,310,556,564 Ishizaka, K., Ishizaka, T., Jacobsen,S., Waaler,B.A. 487, Ignarro,L.J., Lint, T.F., Kishimoto, T., Okudaira, T. 513 George, W.J. 304,305,310 347,369 Jacobson,L.O., see Krantz,S.B. Ignarro,L.J., see Smith,R.J. Ishizaka, K., see Ishizaka, T. 207,229 305,312 214,228,346,347,369 Jacquemin, C., see Haye,B. ligen, C. B., Burkholder, P. M. Ishizaka, K., see Konig, W. 377,380,418 427,456 347,369 JatIe,C.J., Atkinson,J. P., ligen, C. L., Bossen, E. H., Row• Ishizaka,K., see Platt-Mills, T. Gelfand,A., Frank,M.M. lands,D. T., Jr., Burkholder, A. E. 432,459 449,456 P.M. 427,456 Ishizaka,K., see Steinberg, P. J atIe, E. S., see Shevach, E. M. IIIei-Donhoffer,A., see Boros• 360,373 277,293 Farkas, M. 621,650 Ishizaka, T., DeBernardo, R., Jago, M., see Hurley,J. V. 42, 46,64 Inceman,S., Caen,J., Bernard,J. Tomioka,H., Lichtenstein, Jakschik,R.A., Falkenhein,S., 165,196 L. M., Ishizaka, K. 347,369 Parker, C. W. 362,369 Inder,S., see Ford,W.H. 320, Ishizaka, T., Ishizaka, K. 369 338 Ishizaka, T., Ishizaka, K., James,D.M., see Mark,J. 315, Ingerman,c., see Kocsis,J.J. Johansson, G. 0., Bennich, H. 316,339 153,173,179,196,401,419 214,228 James, G. W. L., see Collier, Ingerman,C., see Silver,M.J. Ishizaka,T., see Glovsky,M.M. H.O.J. 494,508 146,153,155,160,201 351,368 Jamieson, G. A., Urban, C. L., Ingerman, C., see Smith, J. B. Ishizaka, T., see Ishizaka, K. Barber,A.J. 110,132 154,157-159,164,165,170, 346, 347,369 Jamieson,G.A., see Pepper, 173,175-177,202 Isliker,H., see Knobel,H.R. D.S. 187,200 Ingerman,C.M., see Silver,M.J. 426,456 Jamieson,J.c., see Ashton,F.E. 172,201 Itkin,A., see Arman,C.G., van 545,560 Ingerman,C. M., see Spector,A. 185,203 Jansc6,N., Jansc6-Gabor,A., A. 182,202 lto,H., see Yoshimoto,A. Szolcsanyi,J. 487,513,557, Innerfield, I. 503, 513 395-397,422 564 Innerfield, I., Bundy,R. E., Iverson,G.M., see Wahl,S.M. Jansc6-Gabor,A., Szolcsanyi,J. Hochberg, R. 503, 513 119,135 557,564 Inoki,R., Toyoda,T., Yama• Ivy,A.C., see Goetzl,F.R. 589, Jancs6-Gabor,A., see Jancs6,N. moto,I. 491,513 590,611 487,513,557,564 Insley, M. Y., see Ford• Iwanaga,S., see Suzuki, T. 465, Jandl,lH., see Abramson,N. Hutchinson,A. W. 547,558, 466,469,519 445,450 563 Jandl,J.H., see Alper,C.A. Intaglietta,M., see Mahler,F. 442,445,450 440,457 Jackson,A.L., see Grant,J.A. Janeway,C.A., see Yoshida, T. Ipsen,J., see BonnycastIe,D.D. 348,351,368 317,342 607,609 Jackson,C.M., see Suttie,J.W. Janis,M., Bach,F.H. 319, 322, Irle,G., see Majno,G. 36,38, 163,202 339 65 Jackson,D.L. 620,653 JanotI,A. 61,65, 185, 196, 286, Irvine,R., see Hall,R.C. 185, Jackson,D.M., see Sevitt,S. 291 194 504,519 JanotI,A., Blondin,J., Sandhaus, Irwin, W.S., see Petz,L.D. 446, Jackson,D.S., Williams,G. R.A., Mosser,A., Malemud, 459 221,228 C. 286,291 690 Author Index

Janoff,A., Rosenberg, R., Jensen,J.A., see Ross,G.D. Johnston, M., see Greenbaum, Galdston,M. 281,291 437,460 L.M. 309 Janoff,A, Zeligs,J. D. 301,305, Jensen, M.S., Bainton,D.F. Johnston, R. B., J r., Klemperer, 310 298,310 M. R., Alper, C. A., Rosen, Janoff,A., Zweifach,B.W. 111, Jepson,J.B., Armstrong, D., F. S. 432,456 112,132,184,196,302,310 Keele,C.A, Stewart,J. W. Johnston,R.B., see Alper,C.A Janoff,A., see Cochrane,C.G. 16,22 442,445,450 443,452 Jepson,J.B., see Armstrong,D. Johnston, T. P., see Davies, G. E. Janoff,A., see Cochrane,S.G. 16,19,471,480,498,506,591, 502, 504, 508 183,185,191 593,608 Jones,C.R., see Goodwin,L.G. Janoff,A, see Ornstein, L. 70, 485,511 Jerushalmy,Z., Kohn,A, Vries, 105 Jones,D.B. 31,49,65 A. de 187, 196 Janoff,A., see Sandhaus,R. Jones,R. L. 410,418 Jessop,J.D., see Vernon• 300,311 Jones,R.L., see Horton,E.W. Roberts, B. 259,265 Janoff,A., see Scherer,J. 303, 400,409,418 312 Jessup, R., seeJohnson,M. 139, Jones,T.B.,Mote,J.R. 314,339 142,175,196 Jaquenoud, P.A., see Boissonas, Jones,T.C. 76,103 R.A. 16,20,464,474,506, Jessup,R., see Ramwell, P. W. Jones, W., see Schuitz,J. 296, 507 607,614 312 Jaques,R., see Riesterer,L. Jimenez,S. A, Dehm, P., Jonsson,C.E., see Hamberg,M. 556,566 Prockop,D.J. 221,228 403,418 Jordon,M.M.,seeHinshaw,L.B. Jarcho,S. 2,3,4,7,21 Job,C.K., see Karat,A.B.A 244,262 184,195 Jasani,M. K. 259,262 Johannsen,R., see Day,N. K. B. Jordon,R.E., see Solley,G.O. J asani, M. K., Parsons, R. R., 437,452 345,373 Roberts,J.M., Tweed,M.F. Johanovsky,1., see Krejci,]. Jorgensen, L., Borchgrevink, 259,262 C.F. 165,196 331, 339 Jasin,H.E., see Cooke,T.D. Jori,A, Bernardi,D. 527, 531, Johanovsky,J., see Svejcar,J. 285,289 534, 558,564 315,341 Javett,S.L., see Coffman,J.D. Jori,A., see Garattini,S. 527, 477,508 Johansson,G. 0., see Ishizaka, T. 528,563 '214,228 Jeffrey,J.J., see Koob,J. T. 287, Joris,l., Majno,G., Ryan,G.B. 291 Johansson,S.A. 183,196 36,65 Jeffrey,1.J., see Senior,R. M. John,S., Berger,N., Bonner,M. Joris,l., see Majno,G. 36,38, 280,293 J.,Schuitz,J. 296,310 66 Johnson,AG., see Landy,M. Jenkin,C.R., see Rowley,D. Joyner, W.L., Carter,R.D., 618,653 621,654 Raizes,G.S., Renkin,G.M. Johnson,A R., Hugli, T. E., 583,586 Jenkins,C.S.P., Meyer,D., Miiller-Eberhard,H.J. 440, Joyner, W. L., see Renkin, E. M. Dreyfus,M.D., Larrieu,M.J. 456 583,586 163,166,196 Johnson,A.R., see Mahler,F. Juan,H., Lembeck,F. 481, Jenkins, C. S. P., Phillips, D. R., 440,457 513,600,601,612 Clemetson,K.J., Meyer,D., Johnson,C.A., see Collier, Juan,H., see Lembeck,F. 481, Larrieu,M.J., Luscher,E.E. H.O.J. 602,609 501,514 139, 166,196 Johnson,C.L., see Green,J.P. J ubiz, W., see Anderson, F. L. Jenkins, C. S. P., see Meyer,D. 361,368 412,415 166,198 Johnson,H. B., see Henson, P. Judah,J.D., see McLean, Jenner,E. 231,262 M. 270, 271,291 AE.M. 47,65 Jennings, M.A., Florey,H. 34, Johnson, M., Jessup, R., Ram• Judge, F., see Ellman,L. 443, 65 well, P. W. 139, 142, 175, 196 453 Jensen,J. 234,262 Johnson, M., Ramwell, P. W. Juhlin, L., Michaelsson, G. Jensen,J., see Nelson,R.A 139, 196 598,600,612 433,438,458 Johnson,R.A., Morton,D.R., Juhlin, L., see Solomon, L. M. Jensen,J.A 437,440,456 Kinner,J.H., Gorman,R.R., 598,615 Jensen,J. A., Esquenazi, V. McGuire,G.C., Sun,F.F., 119,122,132 Whittaker,N., Bunting,S., Kaada, B. 533, 564 Jensen,J.A., see Fuller, L. 437, Salmon,J., Moncada,S., Vane, Kabat,E.A., Mayer,M.M. 454 J.R. 196 235,262 Author Index 691

Kalin, H., see Giatt,M. 76,103 Kaplan,A. P.,seeSchreiber,A. D. Kasakura, S., Lowenstein, L. Kahan,A., Perlik,F., LeGo,A., 436,449,461 321,339 Delbarre,F. 253,262 Kaplan,A. P., see Webster, Kassarich,J., see Rosenthale, Kahlson, G., Rosengren,E. M.E. 472,520 M.E. 186, 201, 605, 614 353,369 Kaplan, A. P., see Weiss,A.S. Katic,F., see Hall,R.C. 185, Kaiser,M.E., see Loew,E.R. 472,521 194 14,22 Kaplan,H., see Spitier,L. 332, Kato,H., see Komiya,M. 466, Kakimoto,T., Oshima, G., Yeh, 341 513 Kaplan, H. B., see Goldstein, H.S.J., Erdos,E.G. 302,310 Kato,H., see Suzuki,T. 176, LM. 268,290,298,309 Kaley, G., Messina,E.J., 202,465,466,469,519 Weiner,R. 175,196 Kaplan,H.S., Gartner,S. 99, Kato,J., see Oshima,G. 473, Kaley,G., Weiner,R. 173,175, 104 516 196 Kaplan,S.S., see Bodel, P. 551, Kaliner, M., Austen, K. F. 306, 561 Kato,R., see Koyama,H. 306, 310,349,369 Kaplow,L.S. 72,104 310 Kaliner, M., Orange,R. P., Kapp,J.A., see Pierce,C. W. Katona,G., Biengio,J.R. Austen,K.F. 348,350,363, 76,105 18,22 369 Kappas,A., see Mueller, M. N. Katz,A.B., see Remold,H.G. Kaliner, M. A., see Orange, R. P. 551,565 331,340 305,311 Karady,S., see Fearn,H.J. 556, Katz,G. 13,22 Kaller,H., Hoffmeister,F., 557,563 Katz,R., Gordon,A.S., Lapin, Kroneberg, G. 502,5 13 Karady,S., see Nagy,S. 552, D.M. 95,104 Kaminker, K., see Schultz, 1. 565 Katz,S.L 241,262 296,312 Karat,A. B. A., Karat,S., Job, Katz,S. 1., Heather,C.J., Parker, Kaminsky, N. 1., see Broadus, C.K., Furness,M.A. 244, D., Turk,J.L. 250,263 A. E. 305, 308 262 Kammerman, S., see Zurier, R. B. Karat,S., see Karat,A.B.A. Katz,S. I., Parker, D., Sommer, 303-305,313 244,262 G., Turk,J.L. 249,263 Kandasamy,B., Girault,J.M., Karim,S. 598,612 Katz,S.l., Parker,D., Turk,J.L. Jacob,J. 621, 631, 633, 634, Karim,S. M. M., see Collier,J.G. 239,249,263,359,361,369 653 598,609 Kaufmann-Boetsch,B., see Kane, M.A., May,J.E., Frank, Karnovsky, M.D., see Orange, Werle,E. 469,521 M. M. 246, 262 R.P. 362,371 Kauritchewa, N., see Henriques, Kane, M.A., see Frank,M.M. Karnovsky, M.J. 34, 54, 65 O.B. 466,469,512 453 Karnovsky, M.J., see Dvorak, Kay,A.B. 329,339 Kang,A.H., Bornstein,P., Piez, A. M. 324,338 Kay,A.B., Austen,K.F. 127, K.A. 217,228 Karnovsky,M.J., see Ryan,G.B. 132,345,369 Kang,A.H., Nagai,Y., Piez, 115,134 Kay, A. B., Pepper,D.S., Ewart, K.A., Gross,J. 209,228,302, Karnovsky,M.L., Lasdins,J., M.R. 120,132 310 Simmons, S. R. 76,104 Kay,A.B., Shin,H.S., Austen, Kantrowitz, F., Robinson,D.R., Karnovsky, M. L., Simmons,S., K.F. 127,132 McGuire,M.B., Levine,L. Glass,E.A., Shafer,A.W., Kay,A. B., Stechschulte,D.J., 178,196 D'ArcyHart, P. 76,104 Austen, K. F. 127,132 Kapitar,M., see Lebez,D. 300, Karnovsky,M.L., see Cox,J.P. Kay,A.B., see Kaplan,A.P. 311 304,308 120.132.470,513 Kaplan,A., Austen,K.F. 449, Karnovsky,M.L., see Nathan, Keats,A.S., see Beecher,H.K. 456 C.F. 252,263,319,325,340 601,609 Kaplan,A. P., Austen,K.F. 18, Karnovsky,M.L., see Nose• Keele,C.A. 480,498,513,596, 22, 346, 369, 472, 490, 513 worthy,J. 113,133 612 Kaplan, A. P., Gray,L., ShalT, Karpatkin,M.H., Karpatkin,S. Keele,C.A., Armstrong,D. R.E., Horakowa,Z., Beaven, 139,196 16, 19, 22, 471, 480, 481, 501, M.A. 352,361,369 Karpatkin,S., see Karpatkin, 513, 588, 589, 591, 593-596, Kaplan,A. P., Kay,A. B., Austen, M.H. 139,196 612 K.F. 120,132,470,513 Karthauser,H.M., see Aber• Keele,C.A.. see Armstrong,D. Kaplan,A. P., Schreiber,A.D., crombie, M. 114,129 16, /9,471,480,498,506,591, Austen,K.F. 18,22 Karunaratne, W. A. E., see 593,608 Kaplan,A.P., see Clark,R.A.F. Cameron,G.R. 207, 227 Keele,C.A., see Jepson,J.B. 12~/31,356,357,367 Kasakura,S. 319,339 16,22 692 Author Index

Keene, W. R., see Bennet, J. L., Kerr,C.B., see Streeten,D.H.P. Klein,I., Levey,G.S. 354,369 Jr. 620,621,650 500,519 Kleineschmidt, A. K., see Rosen• Kefalides,N.A. 211, 217, 221, Kerr,L.P., see Streeten,D.H.P. berg,L. 215,229 229 500,519 Klemperer, M. R., Woodworth, Kefalides, N. A., Denduchis, B. Kessler, E., Hughes, R. c., H.C., Rosen,F.S., Austen, 218,229 Bennett,E.N., Nadella,S.M. K.F. 428,456 Kehl,R., see Werle,E. 473,521 412,418 Klemperer, M. R., see Alper, Keisari, Y., Witz,J. P. 300, 310 Khairallah, P. A., Page, I. H., C.A 429,450 Keith,E.F. 602,605,612 Turker,R. K. 604,605,612 Klemperer,M.R., see Johnston, Kellaway,C.H., see Dale,H.H. Khaitin,V.M., see Sonina,R.S. R. B., Jr. 432,456 13,20 596,615 Klemperer, M. R., see Leddy, Keller,H. U., Bessis,M. 126, Kibrick,S.,seeGreen,J.A. 319, J. P. 434,457 132 330,338 Klenberg, D., see Bergstrom,S. Keller,H.U., Borel,J.F. 119, Kidd,D.J., see Fox,R.H. 477, 384,416 132 510,574,585,594,611 Klett, W., see Habermann, E. Keller,H.U., Sorkin,E. 115, Kim, K. S., see Greenbaum, L. M. 469,512 118, 120, 132, 328, 333,339 473,495,511 Kletzien,R.F., Perdue,J.F., Keller,H. U., see Borel,J.F. Kim, Y. B., see Galanos, C. 618, Springer, A 269,291 119,130 652 Kloeze,J. 156, 196,410,418 Keller,R. 77, 104 Kimball,H.R., see West,B.C. Klose,J., Flickinger,R.A Kellermeyer,R W. 490, 491, 296,313 208,229 513 Kincaid-Smith, P. 187, 196 Knapp,H.R, Jr., see Oelz,O. Kellermeyer,R. W., Brecken• King,F. M.,seeBrady,R.O. 98, 173,200 ridge,R. T. 490, 491, 499, 100 Kniker, W.T. 360,369 513 King,M.K., Wood,W.B., Jr. Kniker, W. T., Cochrane, C. G. Kellett,D.N. 493, 502,513, 620,653 184, 196, 243, 263, 299, 310, 555,556,564 Kingston, W. P., see Flower,R.J. 345,356,360,369 Kelley, L. A, Butcher,R. W. 173, 175, 193, 375, 417, 577, Knobel, H.R., Heusser, c., 305,310 585 Rodrick, M. L., Isliker, H. Kelley, M. E., see Rosenfeld,S. I. Kinlough-Rathbone,R.L., see 426,456 433,445,460 Guccione,M.A 150, 194 Knostman,J.N., see Ruddy,S. Kelly,R. H., Wolstencroft, R.A. Kinlough~Rathbone,R. L., see 446,460 319,331,339 Packham, M.A. 151, 155, Kobayashi, Y., see Maudsley, Kelly,R. H., Wolstencroft,R.A, 161,200 D. V. 365,370 Dumonde,D.C., Balfour, Kinner,J.H., see Johnson,RA. Kobinger, W., see Csongrady,A. B. H. 319,339 196 354,367 Kelley,R.H.,seeDumonde,D.C. Kirby, P.J., Marley,J., Pons• Kobold,E.E., see Thal,A. P. 77, 101 ford, J. R., McDonald, W. I. 499,519 Kelly, R. H., see Franco, M. 336,339 Koch, 7 327-329,338 Kirchner, H., see Altman, L. C. Koch,R. 231,263 Kempf,R.A., Gigli,I., Austen, 119,129,319,337 Kochwa,S., see Weiss,H.J. K. F. 438,456 Kirschbaum, M. B., see 204 Kenatin, T. P., Krueger, C. A, Solomon, L. M. 598, 615 Kocsis,J.J., Hernandovich,J., Cook,D.A. 354,369 Kishimoto, T., see Ishizaka, K. Silver, M. J., Smith,]. B., Kendall, E. c., see Hench, P. S. 347,369 Ingerman,c. 153, 173, 179, 550,564 Kisieleski,D.I., see Booyse,F. 196,401,419 Kenig-Wakshal,R., see Raz,A. 167,190 Kocsis,J. J., see Silver, M. J. 394, 400, 421 Kissel,J.W., see Brown,lH. 146,153,155,160,201 Kennedy,L., see Leibowitz,S. 556,557,562 Kocsis,J.J., see Smith,J.B. 258,263 Kitchen,E.A., see Boot,J.R. 154, 159, 164, 170, 173, 175, Kennedy, W. P., see Morley,]. 175, 190 177,202 554,559,560,565 Klavins,I., see Gilfoil,T.M. Kocsis,J.J., see Spector,A.A. Kerby,G. P., Taylor,S. M. 299, 490,511,597,611 182,202 310 Klebanoff, S. J., Hamon, B. Koebke,K., see Werle,E. 473, Kerckhaert,l A. M., Van den 76, 104 521 Berg,G.J., Willers,J. M. N. Klebanoff,S.J., see Ross,R Koenig, H., ,see Goldstone,A. 250,263 211,214,229 297,309 Author Index 693

Konig, W., Czarnetzki, B. M., Koopman, W. J., Gillis, M. H., Kraut, H., Frey, E. K., Werle, E., Lichtenstein,L. M. 345, 369 David,J.R. 324,339 Schultz,F. 470,514 Konig,W., Ishizaka,K. 347, Koopman, W. M., Gillis, M. H., Kraut, H., see Frey,E.K. 470, 369 David,J.R. 358,369 510 Konig, W., see Czarnetzki,B. M. Koopman, W.J., Sandberg, Kravis,T.C., Zvaifler,N.J. 127, 131, 345, 350, 351, 363, AL., Wahl,S.M., Mergen• 356,369 Kregar,1., see Lebez, D. 300, 367 hagen,S. E. 442,456 Koerten, H. K., see Daems, W. T. 311 Korbut,R., see Gryglewski,R.J. Krejci,J., Pekiuek,J., Svejcar,J., 101 178,194 Koerten,H.K., see Ogawa,R. Johanovsky,J. 331,339 72, 105 Korchak,H., see Noseworthy,J. Krejci,J., see Pekiuek,J. 317, Koethe,S.M., Austen,K.F., 113,133 340 Gigli,1. 437,456 Korn,C., see Beelen,R.H.J. Krejci,J., see Pick,E. 326,340 Komer,D., Schur,P.H., 73,100 Krell, R. D., see Chakrin, L. W. Kunkel,H.G. 244, 263 Kornberg,A., see Scandella,J. 356,357,367 Kohler,P.F., Ten Bensel,R. 382,421 Kretschmer, K. W., see Donald• 446,456 Koslowske,T.C., see Glenn, son, V. H. 440,453 Kohlschiitter,A., see Fischer,H. M.E. 548,559,563 Kretschmer,R.R., see Bamzai, 111,131 Kourilsky, F. M., see Bloch, K. J. A K. 351,366 Kohn,A., see Jerushalmy,Z. 235,240,260 Krieger,E.M., see Greene,L.J. '187,196 Kourilsky,O., see Peters,D. K. 488,511 Krivit, W., see White,J.G. 139, Kohn,J., see Goodwin,L.G. 447,459 204 485,511 Koutts, J., see Mannucci, P. M. Kriz,M., see Jacobsen,S. 466, 166,197 Kohn,J.L., McCabe,E.J., 513 Brem,J. 242,263 Kovats,T.G., Vegh,P. 245, Krogh,A. 13,22,29,65 263 Kohno, E., see Takeguchi, C. Kroneberg, G., see Kaller, H. 395,396,422 Kovats,T.G., see Wolff,S. M. 502,513 Kolb,W.P., Granger,G.A. 247,265 Krueger, C. A., see Kenatin, T. P. 319,332,339 Koyama,H., Kato,R., Ono,T. 354,369 Kolb,W.P.,Morgan,W.T., 306,310 Krueger,G.G., see Weston, Miiller-Eberhard, H. J. Krahenbuhl, 1. L., see Reming• W.L. 287,294 434,456 ton,J.S. 77,106 Krueger, W.C., see Daniels, Kolb,W.P., MUller-Eberhard, Krakauer, K., see Davies, P. E.G. 393,416 H.J. 434,435,456 268,289,301,308 Krupinska,J., see Dembinska• Kolb,W.P., see Podack,E.R. Krakauer, K., see Weissmann, G. Kiec,A. 607,610 434,459 299,313 Krupp,P., Wesp,M. 645, 653 Kolb, W. P., see Zimmermann, Krakauer, K., see Zurier, R. B. Krzywanek,H.J., see Breddin, T. S. 443, 463 295 K. 147,191 Kralios, A. c., see Anderson, Ktejci,J., see Pick,E. 239,264 Komiya, M., Kato, H., Suzuki, F.L. 412,415 Kubisz, P.,Caen,J. 177,196 T. 466,513 Kram,J., see Melmon,K.L. Kondo,K., see Senda,N. 113, 356,358,370 Kubisz, P., see Polasek,J. 177, 124,134 Kram,R., Tomkins,G.M. 200 Kondo,M., Gigli,1., Austen, 306,310 Kuehl,F.A., Humes,J.L., K.F. 428,448,456 Krane,S. M., Pinnell,S.R., Egan,R.W., Ham,E.A., Konzett,H. 17,22,477. 513 Erbe,R.W. 220,229 Beveridge,G.C., Arman, Konzett, H., Stiirmer,E. 477, Krane,S. M., see Harris,E.D., C.G. van 554,565 499,513 Jr. 446,455 'Kuehl,F.A., see Davis, P. 101 Konzett, H.,. see Boissonas,R.A. Krantz,S. B., Jacobson,L. O. Kuehl,F.A, Jr., see Goldberg, 16,20,474,507 207,229 N.D. 354,368 Konzett, H., see Ehringer, H. Krathamer,G., see Lim,R.K.S. Kiistner,H., see Prausnitz,C. 17,20,477,508 607,613 346,372 Koob,J. T., Jeffrey,J.J., Krats\cin,1. L., see Repin, 1. S. Kuhn,D.C., WiIlis,A.L. 173, Eisen,A.Z. 287,291 620,654 196,600,612 Koono,M., see Hayashi,H. Kraut, H., Frey,E.K., Werle,E. Kuhn, D. c., see Weiss,H.J. 537,564 470,514 156,166-171,204 694 Author Index

Kuhn,D,C., see Willis,AL. Lachmann,P.J., see Amos, Laland, S., see Gaarder,A. 150, 141, 146, 153-160, 164, 165, H.E. 317,337 193 166, 168, 169, 173, 175, 178, Lachmann, P. J .. see Alper, C. A. Lamberth, E. L., see Friedman, 181,188,205,382,387,422, 432.450 Z. 159, 193 601,615 Lachmann,P.J .. see Brown. Laminus,M., see·Colwell,J. P. Kuhn, K.,.see Fietzek, P. P. D. L. 235,260 159,191 217,228 Lachmann. P.J., see Gitlin,J. D. Lamont-Havers,R. W., see Kumagai,N., see Abe,K. 499, 428.454 Plotz, C. M. 533,566 506 Lachmann, P.J .. see Hobart, Lamvik,J.()., see Godal,T. Kumakura,S., see Hashimoto, K.l 434,455 251,262 K. 594,611 Lachmann.P., see McCall,C.E. Landau, W., Bishop, G. H. Kunkel, H. G., see Fu, S. M. 441.457 594, 606, 612 428,454 Lachmann, P. J., see Nicol, Landau, W., see Bishop, G. H. Kunkel,H.G., see Komer,D. P.A.E. 430,432,458 591,592,609 244,263 Lachmann,P.J., see Thompson, Landgraber, E., see Schulz, H. Kunkel,H.G., see Miiller• R. A. 434. 462 187.201 Eberhard, H. l 426, 458 Lachmann, P.l; see Trnka,Z. Landis,E. M. 33,34,65,581, Kunze, H., Bohn, E., Vogt, W. 239,265 586 411,419 Lachmann,P.l, see Ziegler,J.B. Lands, W. E. M .. LeTellier, P. R., Kunze,H., Vogt,W. 377,419 430,463 Rome.L.H., Vanderhoek, Kunze, H., see Bartels,J. 380, Lack,C. H .. see Ali.S. Y. 30l. J. y. 400,419 415 307 Lands, W. E. M., Samuelsson, Kunze,H., see Vogt, W. 380, Lack,C.H., see Cook). 255, B. 377, 380, 419 422 261 Lands. W. E. M .. see Cook, H. W. Kupiecki, F. P., see Daniels, Lackie,l M. 111, 132 392.416 E.G. 393,416 Lackie, J. M., see Armstrong. Lands.W.E.M .. see Lee,R.E. Kupiecki,F.P., see Pike,J.E. P.B. 113,114,130 395,419 410,420 Lacombe,M.J., see Wuepper, Lands, W. E. M., see Smith. W. L. Kurasuzi, T., Yoshida, T. 320, K.D. 472,522 401,402.421 342 Lactour,lG., see McKay,D.G. Landsteiner, K .. Chase. M. W. Kutscher,F. 13,22 469,514 314.339 Kutschera,J., see Breddin.K. Ladda,R.L., see Levy, N. L. Landy,M .. Johnson.A.G. 147.191 433,457 618.653 Kuznetsova, V., see Henriques, Laden, c., Quentin,B., Fosdick, Lang, M., see Friedman, Y. ().B. 466.469.512 L. S. 529, 533-536, 538, 540, 396. 397, 399.417 Kwaan.AC., Colwell,J.A.. 565 Lang, W. J .. see Baird. l A. Cruz.S., Suwanwela,N., Ladiges,N.C.J.J., see Gool, 623,626.627,629,649 Dobbie,J. 159,196 J.van 546,548,551,567 Langevoort, H. L.. see Furth. R. Lages, B., see Holmsen, H. 170, van 97.102 195 Langevoort, H. L., see Furth, R. La Belle, A, Tislow,R. 597, Lagrange, P. H., see Mackaness, van 92, 97, 102 612 G.B. 76,105 Lapiere,C.M., see Lenaers,A Laburn, H. P., Rosendorff,C., Lahav,M., see Ginsburg,I. 219.229 Willies, G., Woolf,C. 633. 87, 103 LaPierre,J.-G., Gold, M .. 635,636,653 Lahiri, B., Rosen berg, R., Levison, H., Bryan, A. c., Laburn,H., Woolf,C.l, Talamo,R.C., Mitchell,B., ()range, R. P. 364, 370 Willies, G. H., Rosendorff. C. Bagdasarian,A., Colman, Lapin,D.M., see Katz,R. 95, 633,653 R. W. 469,470,514 104 Laburn,H .. see Woolf,C.l Lahiri, S. c., see Brocklehurst, Lapin,D. M., see Schultz,E.F. 631, 635, 636, 656 W.E. 494,495,507 95,106 Lachmann, P.l 428,456 Lai A Fat,R.F. M., Furth,R. Laraia, P. l, see ()range, R. P. Lachmann, P. J., Coombs, van 76,104 305,311 R.R.A, Fell,H.B., Dingle, Lai A Fat, R. F. M., see McClel• Larke,R. P.B., Wheelock,E.F. l T. 283,292 land,D.B.L. 73,76,104 187,196 Lachmann, P. J., Thompson, Laidlaw, P. P., see Dale, H. H. Larrieu,M.J., see Castaldi,P.A. R.A 235,263,434,457 12,20 139.191 Lachmann, P.J., see Abramson, Laki,K., see Gladner,J.A. 482, Larrieu, M. l, see Jenkins, N. 445,450 511 C.S. P. 139, 163, 166, 196 Author Index 695

Larson,J.B., see Solley,G.O. Leber,P.D., McCluskey,R.T. Legrande, Y., Caen,J. P., 345.373 184, 197, 445,457 Booyse, F. M., Rafelson, M. E., Larsson,e., see Anggard,E. Leber,T. 128,132 Robert,B., Robert,L. 272, 406,408,415 Lebez, D., Kapitar, M., Turk, V., 292 Larsson,e.A., see Bohman. Kregar, I. 300, 311 Legrande, Y., Pignaud,G. 272, S.O. 382,416 Lebowitz,A.S., Lawrence,H.S. 292 Lasagna, L., see Beecher. H. K. 319,330,339 Lehmann, V., see Liideritz, O. 601,609 Lebrun,J., see Deiaunay,A. 618,653 Lasdins,J., see Karnovsky. 118,131 Lehoux,J.-G., see Tan,L. 402, M.L. 75,104 Lechat, P., see Pelit, I. R. 500 422 Lash,). 208,229 516 Lehrer,R.I., see Bourne,H.R. Lattes,R., see Enzinger,F. M. Lecomte,J. 467,495, 501, 514 305,307 224.228 Lecomte,J.,Damas,J. 489,514 Lehrer,R.I., see Henney,e.S. Lattes,R.G., see Wiener,]. Lecomte,J., Petit). M., 305,306,309 51,67 Melon,J., Troquet,J., Leibovich,S.J., Ross,R. 74, Laudenslayer, K. A.. see Cook, Marcelle,R. 499,514 104 e. T. 433,452 Lecomte,J., Troquet,J. 501, Leibowitz,S., Kennedy,L., Laurence,D.R. 560,565 514 Lessof, M. H. 258,263 Lavergne,J. M., see Mannucci, Lecomte,J., see Fischer, P. Leite,M.P., see Garcia Leme,J. P.M. 166,197 183, 193 487, 489, 502, 504, 510, 552, Lavras, A. A. e.. see Henriq ues, LeCompte, R. R., see Graham, 563 O.B. 465,469,512 J.R. 225,228 Lembcck,F., Juan,H. 481, Lawlor, D., see Alexander, B. Leddy,J.P., Frank,M.M., 501,514 163.189 Gaither, T., Baum,]., Lembeck,F., see Juan,H. 481, Lawrence,H.S., see David,J.R. Klemperer,M.R. 434,457 513,600,601,612 315.338 Leddy,J. P., see Graff, K.S. Leme,G.]., see Rocha e Silva, Lawrence, H. S., see Lebowitz, 443,455 M. 95,106 A.S. 319,330,339 Leddy,J. P., see Rosenfeld,S.l. Lemmi,e.A.E., see Moore, Lawrence,H.S., see Valentine, 433,445,460 T.C. 359,371 F.T. 321.341 Lee,e.-H., see Levi,R. 355, Lemmi, e. A. E., see Singclair, Lawrence,T.G., see Wuepper, 370 M.e. 359,372 Lee,e.J., see Sprecher,H. 380, K. D. 472, 522 Lenaers, A., Ansa y, M., 421 Lawrence, W., Jr., see Moore, Nusgens,B.V., Lapiere,e.M. Lee,G.D., see Brade,V. 235, 219,229 T. e. 359, 370 260,429,431,451 Lawton,A. H., see Arellano, Lenon, H. L., see Barnhart, M. I. Lee,G.D., see Nicholson,A. M.R. 15.19 299,307 430, 432,458 Layman, D. L.. McGoodwin. Leon,M.A., see Schwartz,H.J. Lee,LR., see Collier,H.O.J., 326,341 E.B .. Martin,G.R. 218,221, 481,508 229 Leonard,E.J., see Boetcher, Lee,J.B., see McGiff,J.e. 408, Lazarus.G.S. 280. 286. 292. D.A. 345,348,359,366 419 Leonard,E.]., see Lett-Brown, 300.310 Lee,P., see Rooney,P.J. 544, Lazarus.G.S., Brown.R.S., 566 M.A. 357,370 Daniels,J.R .• Fullmer,H.M. Lee,R.E. 645,653 Leonard, K., see Reid, K. B. M. 302.310 Lee,R. E., Lands, W. E. M. 426,460 Lazarus, G. S., Daniels,]. R .• 395,419 Leonardi,R.G., Alexander,B., Brown,R.S .• Bladen.H.A., Lee,T.B., see Augstein,J. 363, White, F. 153, 197 Fullmer.H.M. 302,310 366 Leong Way, E., see Ho, I. K. Lazarus.G.S .• Daniels,J.R., Lefell, M. S., Spitznagel,J. K. 608,611 Lian,J., Burleigh, M. e. 302, 296,311 Lepow,I., see Chapitis,1. 429, 310 Leffell, M.S., see Spitznagel, 431,452 Lazarus,G.S., Dingle,J.T. J.K. 268,293,296,312 Lepow,I., see Pillemer,L. 235, 300,310 Lefort,J., Vargaftig,B. B. 181, 264 Lazarus, G. S., see Dingle, 1. T. 182, 197 Lepow,I. H. 440,457 285,286,290,300,308 LeGo,A., see Kahan,A. 253, Lepow,I.H., Ward,P.H. 18, Lazarus,L., see Bryant,D.H. 262 22 347,366 Legrand, Y.J., Caen,F. M., Lepow,I.H., Willms-Kretsch• Leak, L. V., Burke,]. F. 58, 65, Booyse, M. E., Rafelson, B.R., mer,K., Patrick,R.A., Rosen, 183,196 Rafelson,L.R. 179,197 F.S. 345,348,351,370 696 Author Index

Lepow, I. H., see Dias da Silva, Levine,L., see Hong,S.L. 178, F.H., Rubin,R.H., Austen, W. 234,261,440,452 195 K.F. 348,350,370 Lepow, I. H., see Donaldson, Levine,L., see Kantrowitz,F. Lewis,R.A., Wasserman,S. I., V. H. 440,453 178,196 Goetzl, E. J., Austen, K. F. Lepow, I. H., see Haines,A.L. Levine,L., see Leslie, C. A. 410, 350, 363,370 426,455 419 Lewis, R. L., see Dawson, W. Levine,L., see Tashjian,A.H.J. 410,416 Lepow, I. H., see Minta,J.O. 178,202 Lewis,T. 13,14,22,29,65,514, 429,458 Levine,M.I., see Erdiis,E.G. 573, 574, 586, 588, 592, 594, Lepow, I. H., see Miiller-Eber• 473,509 595-597,605,612 hard,H.J. 427,428,436,458 Levine,R.A. 608,612 Lewis,T., Grant,R.T. 13,22, Lepow, I. H., see Naff,G.B. Levisohn,S.R., Thompson, 28,65,574,586 425,458 E.B. 428,457 Lewis, T., Hess, W. 595,612 Lepow, I. H., see Pensky,J. 459 Levison,H., see LaPierre,J.-G. Lewis,T., Pickering,G.W., Lepow, I. H., see Pillemer,L. 364,370 Rotschild,P. 596,612 428,432,459 Levitan, H., Barker,]. L. 605, Lewis, T., Pochin, E. E. 590, Lepow,I.H., see Taubman,S.B. 612 612 )01;311 Levitt,M., see Davison,C. Lewis, T., Zottermann, Y. 13, Lepow, I. H., see Ward,P.A. 607,610 22 120,135 Levy,D.A. 348, 353, 360, 370 Leyh,P.C.J., see Furth,R. van Lepper,A. W.D., see Outteridge, Levy,M., see Habib,R. 447, 76,102 Leysath,G., see Werie,E. 465, P.M. 319,340 455 Levy,N.L., Snyderman,R., 469,521 Lerner,L.J., Carminati,P., Ladda,R.L. 433,457 Li,C.Y. seeYam,L.T. 70,108 Schiatti, P. 551,565 Lewers,D.T., see Matthew,T.H. Lian,J., see Lazarus,G.S. 302, Lerner, R. A., Glossock, R. J., 188, 198 310 Dixon,F.J. 445,457 Lewin,A.J. 534,565 Lica,M., see Garcia-Leme,1. Lesh,J.B., see Hakim,A.A. Lewis, A. J., see Cottney,J. 182, 557,563 546,564 192 Lichtenstein, L. 99, 104 Leskowitz,S., see Richerson, Lewis,E., Turk,J.L. 241, 246, Lichtenstein, L. M. 347, 348, H.B. 264,314,341 263 349, 351, 363, 370, 553, 565 Leslie, C. A., Levine, L. 410, Lewis, G. P. 471, 475, 477, 482, Lichtenstein, L. M., DeBer• 419 500,514,573,586 nardo,R. 349,370 Lessof, M. H., see Leibowitz, S. Lewis,G.P., Piper,P.J. 178, Lichtenstein, L. M., Gillespie, E. 258,263 197 356,357,370 LeTellier,P.R., see Lands, Lewis,G.P., Wawretscheck, Lichtenstein, L. M., Gillespie, E., W.E.M. 400,419 W.A. 487,514 Bourne, H. 350, 370 Lett-Brown,M.A., Leonard, Lewis,G.P., Work,T. 465, Lichtenstein, L. M., see Adams, E.J. 357,370 470,514 G. K. III 364,365 Leventhal,M., see Majno,G. Lewis,G.P., see Edery,H. 473, Lichtenstein, L. M., see Bourne, 36, 38, 65, 66 482, 487, 497, 508, 594, 610 H.R. 305,307,345,350,366, Leventhal, M. M., see Pietra, Lewis,G.P., see Eisen,V. 502, 553,562 G.G. 38,66 509 Lichtenstein,L. M., see Bruce, Lever, W. F. 223,229 Lewis,G.P., see Elliot,D.F. C. A. 348,366 Levey, G. S., see Klein, I. 354, 16,21,464,474,477,478,480, Lichtenstein, L. M., see Conroy, 369 509,574,585 M.C. 345,363,367 Levi,R., Capurro,N., Lee,C.-H. Lewis,G.P., see Fox,R.H. Lichtenstein,L. M., see Czar• 355,370 477,510,574,585,594,611 netzki, B. M. 127, 131, 345, Levi,R., see Capurro, N. 355, Lewis,G.P., see Hilton,S.M. 350,351,363,367 367 469,512 Lichtenstein, L. M., see Gilles• Levin, R. J., see Bell, W. R. 246, Lewis,M.R., see Rich,A. 315, spie, E. 349, 368 260 341 Lichtenstein, L. M., see Glovsky, Levine, B. B., see Benacerraf, B. Lewis,M.S., see Piez,K. 216, M.M. 351,368 238,260 229 Lichtenstein, L. M., see Grant, Levine,L. 426,457 Lewis,M.S., see Piez,K.A. 229 J.A. 347,351,368 Levine, L., see Hong, S.-c. L. Lewis,R.A., Goetzl,E.J., Lichtenstein,L. M., see Ishizaka, 412,418 Wasserman,S. I., Valone, T. 347,369 Author Index 697

Lichtenstein, L. M., see Konig, Lin,G.N., see Lim,R.K.S. Logie,P.S., see McGregor,D.D. W. 345,369 592,612 76,104,128,133 Lichtenstein, L. M., see Mal• Lin,M.T., Chai,C.Y. 621,653 Logue,G.L., see Rosse, W.F. veaux,F.l. 347,370 Lin,M.T., see Chai,L.Y. 621, 449,460 Lichtenstein, L. M., see Newball, 650 Loh,H.H., see Ho,I.K. 608,611 H.H. 345,348,351,371 Lohmann-Matthes, M. L. 77, 104 Lin,S., Santi,D. Y., Spuddich, Lichtenstein, L. M., see Plaut, M. Lohmann-Matthes, M. L., 1.A. 269,292 345,356,357,359,371 Fischer,H. 77,104 Lichtenstein,L.M., see Rosz• Lin,S., see Spudich,l.A. 269, Lohmann-Matthes, M.-L., kowski, W. 356, 358, 372 293 Ziegler,F.G., Fischer,H. Lichtenstein, L. M., see Thomas, Lindahl,O. 593,613 319, 325,339 L.L. 351,365,373 Linscott, W. D. 427,457 Loirat,C., see Habib,R. 447, Liddle,G.W., see Broadus, Linscott, W. D., Cochrane, C. G. 455 A. E. 305, 308 443,457 Lolekha,S., Dray,S., Gotoff, Lie,K.l., see Downing,D.T. Linscott,W.D., see Huber,H. S.P. 319,325,339 414,417 277,291,441,455 Long, E. R. 523, 565 Liebelt,R.A., see Delmonte,L. Lint,T.F., see Ignarro,L.1. Lonigro,A.l., see McGiff,1.C. 95,101 304,305,310 408,419,488,514,606,613 Light,R.1., Samuelsson,B. Lipsky, P. E., see Rosenthal, Loo,1. van de, see McNicol, 384,419 A.S. 76,77,106 G.P. 143,197 Likewise, 13 Lipton,l. M. 627,653 Loos,M., Yolanakis, 1. E., Lim,R.K.S. 16,17,22,480, Stroud,R.M. 449,457 Lipton,l.M., Fossler,D.E. 481, 501, 514, 588-591, 594, Loos,M., see Raepple,E. 448, 621, 624, 625, 635, 637, 653 596,597,602-604,606,612 449,459 Lim,R.K.S., Guzman,F. 596, Lipton,l.M., Welch,l.P., Louie, A. 1., Dixon,G.H. 306, 612 Clark, W. G. 621, 626, 627, 311 Lim, R. K. S., Guzman, F., 653 Loveday, c., see Eisen, Y. 489, Rodgers,D. W., Gotto, K., Lish,P.M., McKinney,G.R. 502,509 Braun, c., Dickerson, G. D., 501,514 Lowbury, E. 1. L., see Sevitt,S. Engle,R.l. 22,481,501,514, Lish, P.M., see Brown,l.H. 504,519 589,590,600,603,612 556, 557, 562 Lowe,D.M., see Reid,K.B.M. Lim,R.K.S., Lin,G.N., Guz• Lisk, R. D., see Breckenridge, 426,459 man,F., Braun,C. 592,612 B. McL. 636,650 Lowe,l.S., see Davies,G.E. Lim,R.K.S., Liu,C.N., Guz• Liskay,R., see Bennett, 1. 382, 502,504,508 man,F., Braun,C. 16,22 416 Lowenhaupt, R., Nathan, P. Lim,R.K.S., Krathamer, G., Lister, 7 187,197 Guzman,F., Fulp,R. 607, Liu,C.N., see Lim,R.K.S. Lowenstein,L., see Kasakura,S. 613 16,22 321,339 Lim,R.K.S., Miller,D.G., Lobo,A.A., see Ford-Hutchin• LU,G., see Siegmund,E.A. Guzman,F., Rodgers,D. W., son,A. W. 547,563 589, 594, 596, 597, 602, 614 Wang,R.W., Chao,S.K., Lobue,l., see Gordon,A.S. 95, Lu, W. C. 187, 197 Shih, T. Y. 589, 594, 613 103 Luckner,G., Renz,P. 411,419 Lim,R.K.S., see Dickerson, Lobue,1., see Schultz,E.F. 95, Lucy,l.A., see Ahkong,Q.F. G.D. 591,610 106 115,129 Lim,R. K.S., see Guzman,F. LoBuglio,A. F., see Chervenick, Luduena, M.A., see Wessells, 16, 17,21,481,501,511, P.A. 76,93,100 N. K. 140,204, 269,294 589-591, 593, 594, 596, 597, Lockshin,M., see Gocke,D.l. Ludwig, 7 599,602,603,605,611 242,262 Ludwig,A.W., see Boas,N.F. Lim,R.K.S., see Potter,G.D. Lockshin, M. D. 287, 292 216,227 593,614 Lobbecke,E.A. 498,514 Liibke, K., see Schriider,E. Lim, W. c., see Slonecker, C. E. Loevenhardt,A.S., see Amberg, 500,518 88, 106 S. 529, 532, 560 Liideritz, O. 618,653 Lima,A.O. 495,514 Loew,E.R. 14,22 Liideritz,O., Galanos, c., Limaos, E. A., see Prado,1. L. Loew,E.R., Kaiser,M.E., Lehmann, Y., Nurminen, M., 466,517 Moore, Y. 14,22 Rietschel,E. T., Rosenfelder, Limas,C.l., Cohn,1.N. 396, Loewi,G., see Temple,A. 270, G., Simon,M., Westphal,O. 397,419 293 618,653 698 Author Index

Liideritz,O., Westphal, 0., MacFarlane,D.E., see Smith, . Maison,G.L., see Winder,C.V. Staub,A.M., Nicaido,H. J.B. 375,421 601,605,616 653 Macfarlane,J.see Rothstein,G. Majerus, P. Q., Baenziger, N. L., Liideritz,O., see Galanos, C., 106 Brodie,G.N. 142,197 618,652 MacFarlane,R.G. 61,65 Majerus,P.W., see Roth,G.J. Liideritz,O., see Rietschel,E.T. Machida, Y., see Corey,E.J. 179,201,383,421 618,654 171,192 Majno,G. 475,477,514 MacIntyre,D.E., Gordon,J.L. Majno,G., Gilmore,V., Leven• Liihr,R., see GreelT,K. 467, 153, 156, 158, 161, 163, 197 thal, M. 38, 65 469,499,511 Mackaness,G.B. 76,104 Majno,G., Palade,G.E. 9,22, Liischer,E.F., see Gugler,E. Mackaness,G.B., Blanden,R.V. 34, 36, 38, 65, 475, 515, 581, 165,194 325,339 583,586 Liischer,E.F., see Meuller• Mackaness, G. B., Lagrange, Majno,G., Palade,G.E.,Schoefl, Eckhardt,C. 184,198 P. H., Miller, T. E., Ishibashi, T. G.1. 36, 65, 574, 581, 583, Liischer,E.F., see Siegel,A. 76,105 586 272,293 MacKay,M.E., see Wilhelm, Majno,G., Ryan,G.B., Gab• LulT,R.H., see Cranston,W.I. D. L. 478,522 biani, G., Hirschel, B. S., 621,640,641,651 Mackey,H.K., see Brown,J.H. Irle,G., Joris,1. 36, 38, 65 LulT,R.H., see DulT,G.W. 636, 555,556,562 Majno,G., Shea,S.M., Leven• thal, M. 36, 66 651 Macklin,A. W., see Vinegard, Majno,G., see Cotran,R.S. LulTt,E., see Vogt, W. 380,422 R. 528, 530, 567 36,42,45,46,63,486,502,508 Mackmanus,J.P., see Whitfield, Luft,J.H. 31,34,65,111,132 Majno,G., see Gabbiani,G. J.F. 322,341,497,521 Lukes,R.J. 99,104 38,64,210,223,224,228 Maciaren,A.J., see Bach,S. Lund-Olfsen, K., Menander, Majno,G., see Joris,!. 36, 65 427,450 K. B. 549,565 Majurus,P.W., see Brodie,G.N. Macmahon,R.E., see Dawson, Lundblad,R.L., see Moham• 139,153,191 W. 410,416 med,S.F. 152,198 Makman,M.H. 356,370 Macmorine,D.R.L., see Burke, Lunskis,B., see Poskitt,T.R. Malawista,S.E., Gee,J.B.L., J.S. 270,289 Bensch,K.G. 269,292 432,459 MacNab,G.N., see Alper,C.A. Malawista,S.E~ see Bensch, Luscher, E. E., see Jenkins, 430,441,442,450 K. G. 303, 304, 307 e.S P. 139,166,196 Maddox,I.S. 395,419 Malawista,S.E., see Bodel,P. Lykke,A. W.J., see Bignold, MadolT,M.A., see Terada,H. 551,561 L. P. 478,506 186,203 Malawista,S.E., see Wright, Lykke,A. W.J., see Spector, Madsen,J.E., see Avella,J. D.G. 287,294,303,304,313 W.G. 61,66 365,366 Malemud,C., see JanolT,A. Lynen,R., see Vogt,W. 429, Maegraith,B.G., see Onabanjo, 286,291 447,462 A.O. 493,516 Malik, K. U., see McGilT,J. C. Lynn, W.S., see Tainer,J.A. Maher,J.F., see Matthew,T.H. 488,514,606,613 120,134 188, 198 Maling,H.M., Webster,M.E., Lynn,W.S., see Turner,S.R. Mahler,F., Intaglietta, M., Williams,M.A., Saul, W., 120,135,176,203,375,376, Hugli,T.E., Johnson,A.R. Anderson, W., Jr. 480,503, 422 440,457 515 Maier,L., see Werle,E. 469, Maling,H.M., see Webster, 470,471,521 M.E. 490,491,502,503,521 Maatta,K., see Toivanen,P. Maillard,1., Bloom,B.R. 319, Malinski,C. 353,354,370 551,566 339 Malmsten, c., Hamberg, M., Maayani,S., see Green,J.P. Maillard, J. L., Pick, E., Turk, Svensson,J. 146, 157, 166, 361,368 J.L. 239,263 168,171,172,197 MacArthur,J.G., Alstead,S. Maillard,J.L., Voisin,G.A. Malmsten, c., Hamberg, M., 527,531-533,565 241,263 Svensson, J., Samuelsson, B. MacCartney,J. 2 Maillard,J.L., Zarco,R. M. 406,419 MacDermott,R.P., see Rocklin, 241,263 Malmsten,c.L., see Corey,E.J. R.E. 332,341 Maillard,J.L., see Fallah,H.A. 171,192 Macfarlane,A. S. 582,586 358,368 Malveaux,F.J., Conroy,M.C., Macfarlane, D. E., see Mills, Maiorano,M., see Praga,c. Adkinson,N.F., Jr., Lichten• D. e. B. 577,586 164,200 stein, L. M. 347,370 Author Index 699

Mandel,M.J., see Weston,W.L. Mariano,M., see Spector,W.G. Mason,J.e., see Curry,F.E. 287,294 69,87,107 581,582,585 Mandle,R.J., see Nilsson, U.R. Mark,J., James,D.M. 315, Mason,R.G., see Mohammed, 428,433,458 316,339 S.F. 152,198 Mangianello, V., Evans, W. H., Markham,J. W., see Armstrong, Mason,R.G., see Rodman, S tossel, T. P., Mason, R. J., D. 480, 506, 591, 593, 608 N.F. 163,201 Vaughan,M. 305,311 Markowitz,R.A, see Smith, Mason, R. J., see Mangianello, V. Manganiello, V.e., see Stoner,J. G.M. 596,615 305,311 Massarich,J., see Rosenthale, 346,373 Marley,E., see Artunkal,A.A. 621, 628, 629, 631, 632, 647, M.E. 598,614 Mannheim,S., see Pick,E. 317, Mast,S.O. 113,133 340 649 Marley, E., see Nistico,G. 627, Mathias,A. P., see Holdstock, Manni,J.A., Miiller-Eberhard, 654 D.J. 574,586 H.J. 434,457 Marley,J., see Kirby,P.J. 336, Mathison,P.A., see McDonald, Mannik,M., see Arend,W.P. 339 J. R. 351,370 73,99 Marley,P.B., see Bedwani,J.R. Matschinsky, M., see Marrazzi, Mannucci, P. M., Meyer, D., 409,415 M.A. 412,413,419 Ruggeri,Z. M., Koutts,J., Marmorstein, B. L., see Matsen,J.M., see Wannamaker, Lavergne,1. M. 166, 197 Thompson,J.S. 352, 373 L. W. 273,293 Matsumara, M., see Hayashi, H. Mansfeld, V., see Hladovec, J. Marnett,L.J., W1odawer,P., 537,564 502, 512 Samuelsson,B. 401,419 Matsuzaki, M., see Umezawa, H. Mantegazza,P. 605,613 Marney,S.R., Jr., see DesPrez, 300,312 Mantovani, B. 442,457 R.M. 172,184,192 Matthew,M., see Dumonde, Marcel, Y. L., Christiansen, K., Marquis,N.R., see Amer,M.S. D.C. 317,331,338 Holman,R.T. 380,419 156, 189 Matthew,T.H., Hogan,G.P., Marr,G.G., see Horton,E.W. Marcelle,R., see Lecomte,J. Lewers,D.T., Bauer,H., 400,418 499,514 Maher,J.F., Schreiner,G.E. Marrazzi, M. A., Matschinsky, Marchesi,V.T. 51,66 188,198 Marchesi,V.T., Florey,H.W. M. 412,413,419 Matthyssens,G.E., Hurwitz,E., 51,66,111,133,584,586 Marsh,J.e., see Boggs,D.R. Girol,D., Sela,M. 359,370 Marchesi, V. T., Gowans, J. L. 95,100 Mattie,H., see Furth,R., van 51,66 Marsland,D., Tilney,L.G., 79,82-84,86,102 Marcus,A.J. 139,142,197 Hirshfield, M. 304,311 Maudsley,D. V., Kobayashi, Y., Marcus,A.J., Ullman,M.L., Marten,S., see Morsdorf,K. Williamson, E., Bovaird, L. Safier, L. B. 177,197 482,515 365,370 Marcus,A.J., Zucker,M.B. Martin,F.H .. Baile,e.A. 626, Mauel,J., Noerjasin,B., Behin, 162, 163, 165, 197 653 R. 76, 105 Marcus,AJ., Zucker-Franklin, Martin,G.R., see Layman,D.L. Maxwell,J. H., see B1att,1. M. D., Safier,L.B., Ullman,H.L. 218,221,229 99,100 272,292 Martin,G.R., see Miiller,P.K. May,J.E., Frank,M.M. 457 Marcus,A.J., see AI-Mondhiry, 219,229 May,J., see Frank,M.M. 427, H. 179,189 Martin,G.R., see Piez,K. 216, 449,453 Marcus,R.L., Shin,H.S., Mayer, 229 May,J.E., see Kane,M.A 246, M. M. 432,457 Martin,G.R., see Wahl,L.M. 262 Marel-Morage,L., see Peters, 280,287,293 Mayer, M. M. 436,457 D.K. 447,459 Martin,L.E., see Spitznagel, Mayer, M. M., see Abramovitch, Margaretten,W., McKay,D.G. J. K. 268,293 A. S. 436,450 184,185,197,246,263 Martin,R.R., see Crowder,J.e. Mayer,M.M., see Borsos,T. Margolin,S. 589,597,602,613 268,289 428,436,451 Margolin,S., see Vander Wende, Martin Esteve,1., see Puig Mayer,M.M., see Brade,V. C. 597,615 Muset, P. 608,614 235,260,429,431,451 Margolis,J. 471,515 Martres,M.-P., see Baudry,M. Mayer,M.M., see Cook,C.T. Margolis, J., Bishop, E. A 466, 354,355,366 433,452 471,515 Mason,B., see Wilhelm,D.L. Mayer, M. M., see Goldlust, Margolis,J., Bruce,S., Star• 486, 504, 522, 575, 579, 587 M.B. 433,434,454 zecki,B., Horner,G.J., Mason,D.T., Melmon,K.L. Mayer, M. M., see Hammer, Haimagyi,D.F.J. 467,515 477,515 C. H. 433-435,455 700 Author Index

Mayer,M.M., see Kabat,E.A. McClatchley, W., Snyderman, McGregor, D. D., Logie, P.S. 235,262 R. 175,197 76,104,128,133 Mayer,M.M., see Marcus,R.L. McClelland,D.B.L., LaiA Fat, McGuire,G.C., see Johnson, 432,457 R.F.M., Furth,R., van 73, R.A. 196 Mayer, M. M., see Nicholson, 76, 104 McGuire, M. B., see Kantrowitz, A. 430, 432,458 McClenaghan, M. D., see F. 178,196 Mayer,M. M., see Rommel,F.A. Haslam,R.J. 150, 160, 194 McInroy,R.J., see Russell,R.J. 434,435,460 McClure, W. B., see Amberg,S. 120, 133 Mayer,M.M., see Shin,H.S. 529, 532,560 McInroy,R.J., see Wilkinson, 428,433,434,436,448,449, McCluskey,R. T., see Leber, P. P.C. 119, 120, 125, 126, 136 461 D. 184, 197,445,457 McIntire,F.e., Sproull,M. 15, Mayer,M.M., see Sitomer,G. McConnell,D.J. 469, 470, 514 22 428,461 Mcconnell-Mapes,J.A:, see McKay,D.G. 197 Mayer,M.M., see Stroud,R.M. Niisson,U.R. 428, 433, 458 McKay,D.G., Lactour,J.G., 428,448,462 McCutcheon,M. 115,116,132 Parrish,M.H. 469,514 Mayerson,H.S., Wolfram,C.G., McDevitt,H.O., see Segal,S. McKay,D.G., Shapiro,S.S., Shirley,H.H., Jr., Wasserman, 359,372 Shanberge,J.N. 184, 197 McDonald,J.R., Mathison, K. 33,66 McKay,D.G., see Margaretten, P.A., Stevenson,D.D. 351, Mayhew, B., see Asherson,G.L. W. 184, 185, 197, 246, 263 370 128,130 McKay, I. C., see Wilkinson, McDonald, W.I., see Kirby, P.J. McAndrews,E.J., see Appen• P.e. 121,135,136 336,339 zeller,O. 557,560 McKay,S., see Russell,R.J. McArthur,J.N., Dawkins,P.D., McDonald-Gibson, W., see 120,133 Smith,M.J.H., Hamilton, Greaves,M.W. 599,611 McKerrow,C.B. 98, 105 E. B. D. 558,565 McDonough,J., see Tashjian, McKinney,G.R., see Lish,P.M. McArthur,J.N., Smith,M.J.H., A.H.J. 178,202 501,514 Freeman,P.C. 547,565 Mcduffie,F.C., see Hunder,G.G. McLaren, M., see Ringrose, P. S. McBugler,M., see Habib,R. 446,456 286,287,292 447,455 McFarland, W., Heilman, D. H. McLean, A. E. M., Ahmed, K., McCabe,E.J., see Kohn,J.L. 115,132 Judah,J.D. 47,65 242,263 McFarland,W., Heilman,D.H., McLean,R.H., Michael,A.F. McCall,C.E., Chatelet,L.R., de, Moorhead,J.F. 115, 132 446,447,457 Brown,D., Lachmann,P. McLeod, B., Baker, P., Behrends, McFarland, W., Schechter, G. P. 441,457 e.,Gewurz,H. 447,457 115,132 McCall,E., Youlten,L.J.F. McLoughlin, M., see Wilkinson, McFarlane,D.E. 197 173, 175, 197 P.e. 120,136 McCall,E., see Higgs,G.A. McFarlane, D. E., see Mills, McMaster, P. D., see Hudack, 175, 195 D.e.B. 175,198 S. 59,64 McCallum,N.E.W., see Hurley, McFarlane,D.E., see Smith,J.B. McMorine,D.R.L., see J.V. 34,64 McFarlane,R.G. 151, 172, Mustard,J. F. 176,199 McCarthy,D.A., Potter,D.E., 197 McNicol,G. P., Mitchell, Nicolaides,E.D. 472, 514 McGiff,J.C., Terragno,A.M., J.R.A., Reuter, H., Loo,J., McCarthy,D.A., see Nicolaides, Malik,K. U., Lonigro,A.J. van de 143, 197 E.D. 516 488,514,606,613 McQuarrie,D.G., see Davis, McCarthy,D.S., see Nicolaides, McGiff,J.e., Terragno,N.A., R. B. 185, 192 E.D. 464,500,516 Strand, J. e., Lee, J. B., McQueen,A., Hurley,J.V. 54, McCartney,A.C., see Russell, Lonigro,A.J., Ng.K.K.F. 65 R.J. 120,133 408,419 McQueen, A., see Hurley,J.V. McCarty,D.J., Jr. 490,514 McGoodwin,E.B., see Layman, 38,42,64 McCarty,D.J., Hollander,J.L. D.L. 218,221,229 Meacock,S.C.R., see Crunk• 303,311 McGoodwin,E.B., see Miiller, horn, P. 488,508 McCarty,D.J., see Phelps,P. P. K. 219,229 Medeiros,M.C., see Reis,M.L. 491,516,589,590,600,614 McGovern,V.J. 49,65 471,517 McCarty,D.J., Jr., see Phelps, McGrade,M., see Shazo,C.V., Medicus,R., see Gotze,O. 454 P. 490,499,516 de 452 Medicus,R.G., Gotze,O., McCarty,M., see Ayoub,E.M. Mcgrade,M.T., see Deshazo, Miiller-Eberhard,H.J. 429, 273,288 C. V. 299,308 431,458 Author Index 701

Medicus,R.G., Schreiber,R.D., Menendez-Cepero, E., see Meyer, D., see Jenkins, C. S. P. Gotze,O., Muller-Eberhard, Miyares-Cao, e. M. 384, 139, 163, 166, 196 H.J. 458 419 Meyer,D., see Mannucci,P.M. Meeker,W.R., see Davis,R.B. Mengel,J., see Chakrin,L. W. 166,197 185,192 356. 357, 367 Meyer,H.H., see Frolich,A. Meeks,M., see Colwell,J.P. Menigan, T. C., see Epstein, L. B. 593,611 159,191 330,338 Meyer,U., see Vogt,W. 380, Mehrer,M.M., see Fried,J. Menkin, V. 3, 4, 15, 16,22, 59, 422 412, 417 66,526,565 Meyers,O.L., Shoji,M., Haber, Melai,A., see Vincent,J.E. Menkin,V., Durham,N.C. E., Remold,H.G., David,l.R. 168, 172,203 530, 543, 565 331,339 Melby,J., Egdahl,R., Spink,W. Menzel,J., see Gemsa,D. 305, Meyers,O.L., see Rocklin, 550,565 308 R.E. 321,341 Melmon,K.L., Bourne,H.R., Mergenhagen,S.E., see Altman, Michael,A.F., see McLean, Weinstein, Y., Sela, M. 359, L.C. 332,337 R.H. 446,447,457 370 Mergenhagen, S. E., see Brier, Michael,A.F., see Westberg, Melmon, K. L., Bourne, H. R., A.M. 119,130 N.G. 447,463 Weinstein, Y., Shearer,G.M., Mergenhagen,S.E., see Gewurz, Michaels,D. W., see Abramo• Kram,J., Bauminger,S. H. 427, 446, 454 vitch,A.S. 436,450 356,358,370 Mergenhagen,S.E., see Horton, Michaelsson,G., see iuhlin,L. Melmon,K.L., Cline,M.J. J.E. 319,330,339 598,600,612 473,491,496,497,515 Mergenhagen, S. E., see Koop• Michal,F. 148, 151, 152, 198 Melmon,K.L., Webster,M.E., man, W.J. 442,456 Michal,F., see Ahtee,L. 145, Goldfinger, S. E., Seegmiller, Mergenhagen, S. E., see Snyder• 189 J.E. 491,498,499,515,590, man,R. 118, 129, 134, 234, Michel,C.e., see Curry,F.E. 594,600,613 264,301,312,440,461 581,582,585 Melmon,K.L., see Bourne,H.R. Mergenhagen,S.E., see Wahl, Michell,J.R.A., Sharp,A.A. 345,350,366,553,562 L. M. 280,287,293 151,198 Melmon,K.L., see Cline,M.l Merigan,T.C. 330,339 Middleton,J.M., see Hall,R.C. 502,507 Merler,E., see Donaldson, V.H. 185, 194 Melmon,K.L., see Henney,e.S. 440,453 Miert,A.S., van 618,655 Merrifield, R. H. 464,515 305,306,309 Miert,A.S., van, Essen,J.A., Merrill,J.B., see Strom,T.B. Melmon,K.L., see Mason,D.T. van, Thorp,G.A. 640, 655 477,515 306,312 Merrill,J. P., see Hunsicker, L. G. Miert,A.S., van, Frens,J. 626, Melmon,K.L., see MiIler,R.L. 655 496,515,524,565 446,447,456 Messina,E.J., see Kaley,G. Migliorini,R.H., see Garcia Melmon,K.L., see Mozes,E. 175,196 Leme,J. 487, 510, 552, 563 358,371 Mestecky,J., see Boackle,R.J. Mihaescu,S., see Ghetie,V. Melmon,K.L., see Segal,S. 451 300,308 359,372 Metcalf,D. 95,105 Mihm, M. C., Jr., see Dvorak, Melmon,K.L., see Shearer, Metcalf,D., see Bradley,T.R. A. M. 359,367 G. M. 359,372 93,100 Miles,A.A. 475,515 Melmon,K.L., see Weinstein, Metcalf,D., see Stanley,E.R. Miles,A.A., Miles,E. M. 16,22, Y. 359,373 95,107 60,66,475,515,579,586 Melon,J., see Lecomte,J. 499, MetchnikolT,E. 3, 4, 9, 10, 11, Miles,A.A., Wilhelm,D.L. 514 18, 22, 68, 105, 120, 128, 133, 16,23,477,478,515 Melrose,G.J.H.,seeBaum• 303,311 Miles,A.A., see Feldberg, W. garten, A. 477,506 Metzger,H., see Mendoza,G. 573,585 Menander, K. B., see Lund• 347,370 Miles,A.A., see Freund,J. 477, Olfsen, K. 549, 565 Meuller-Eckhardt,C., Luscher, 478,510 Mendes,J., see Prado,J.L. 471, E.F. 184,198 Miles,A.A., see RatnolT,O.D. 517 Meuret,G. 83,86,105 471,517 Mendoza,G., Metzger,H. 347, Meuret,G., HolTmann,G. 83, Miles,A.A., see Wells,F.R. 42, 370 86, 105 46,67 Mene, G., see Biozzi,G. 16, Meyer,D., Jenkins,e.S.P., Miles,A.A., see Wilhelm,D.L. 19 Dreyfus,D. 166,198 478,522 702 Author Index

Miles,E.M., see Miles,A.A. Milton,A.S., see Dey,P.K. Molenaar,J.L., see Ter Laan,B. 16,22,60,66,475,515,579,586 638,642,643,651 440,462 Mill,P.J., see Freund,J. 477, Milton,A.S., see Feldberg, W. Monahan,T.M., see Abell,C.W. 478,510 621,638,641,644,651 306,307 MiII,P.J., see Wilhelm,D.L. Milton,A.S., see Harvey,C.A. Moncada, B., Day,N.K.B., 478,522 633,638,641,652 Good,R.A., Windhorst,D.B. Miller,D., see Pace-Asciak,e. Milton-Thompson,G.J., see 426,458 409,420 Pounder,R.E. 355,371 Moncada, S. 598, 613 Miller,D.G., see Lim,R.K.S. Minard, D., see Rosenthal,S.R. Moncada,S., Bunting,S., 589,594,613 480,518 Mullane,K., Thorogood,P., Miller,D.R., see Wuepper,K.D. Minkes,M., see Needleman,P. Vane,J.R., Raz,A., Needle• 472,522 158,199 man,P. 198 Miller,E.J. 217,229 Minta,J.O. 458 Moncada,S., Ferreira,S.H., Miller,E.J., see Chung,E. 217, Minta,J.O., Lepow,1.H. 429, Vane,J.R. 154, 173, 198, 227 458 488, 515, 588-590, 592, 594, Miller,J.W. 592,613 Mirjah,D.D., see Pepys,M.B. 595, 597, 600, 601, 604, 606, Miller,L.M., see Arman,e.G. 442,459 613 van 480, 487, 502, 504, 520, Mirsky,A.E., see Pogo,B.G.T. Moncada,S., Needleman,P., 576,586 323,340 Bunting,S., Vane,J.R. 613 Miller,O.N., see Paulsrud,J.R. Misiewicz,J.J., see Pounder, Moncada, S., Pontieri, V. 601, 414,420 R. E. 355,371 613 Miller,R.E., see Bell,W.R. Mitchell,B., see Lahiri,B. 469, Moncada,S., see Bunting,S. 246,260 470,514 155, 191, 601, 609 Miller, R. L., Melmon,K.L. Mitchell,D., see Cranston, W.1. Moncada,S., see Ferreira,S.H. 524,565 621, 632, 640, 648, 649, 650 17,21,178,193,488,501,503, Miller,R.L., Webster,M.E., Mitchell,l, see Basten;A. 77, 509, 510, 527, 563, 575, 576, Melmon, K. L. 496, 515 99 585, 589, 590, 592, 594-600, Miller,T.E., see Mackaness, Mitchell,J.R.A., see McNicol, 604-606,610 G.B. 76,105 G. P. 143,197 Moncada,S., see Gryglewski, Miller, W.L., see Nishizawa, Mitchell,J.S. 13,23 R.J. 142,158,175,194 E.E. 15~ 175, 199 Mitrani, S., see Ginsburg, I. Moncada,S., see Herman,A.G. Millroy,S.J., Poole,A.R. 285, 87,103 18~195,600,605,611 292 Mittman,e. 179,198 Moncada,S., see Johnson,R.A. Mills,D.C.B. 144,146,150, Miyamoto,T., Yamamoto,S., 196 151, 152, 166, 198 Hayashi,O. 382, 394,419 Moncada,S., see Needleman,P. Mills,D.C.B., McFarlane,D.E. Miyares-Cao, C. M., Menendez• 154,157,199,601,613 175,198,577,586 Cepero,E. 384,419 Moncada,S., see Nijkamp,F.P. Mills,D.C.B., Robb,I.A., Miyoshi,H., see Hayashi,H. 412,420 Roberts,G.C.K. 146,158, 537,564 Mongar,J.L., see Foreman,J.D. 178,198,272,292 MizeI,S.B., Wilson,L. 269, 349,368 Mills,D.C.B., Roberts,G.C.K. 292 Monier,R., see Prado,J.L. 152,198 Moberg,G. P. 550,565 471,517 Mills,D.C.B., Smith,J.B. 150, Mododell, M., see Fischer, H. Montague,B., see Nakano,J. 198 111,131 408,419 Mills,G.L., see Armstrong,D. Moelle,R., see Riihl,H. 119, Mooney,lJ., see Rosendorff,e. 480,506 133 620,621,646,648,654 Milton,A.S. 631,653 Morsdorf, K. 482, 515 Moore,A.R., Hall,J.G. 128, Milton,A.S., Harvey,C.A. Morsdorf, K., Marten, S., 133 621,633,653 Purchert,1. 482,515 Moore,M.A.S., Williams,N. Milton,A.S., Wendlandt,S. Morsdorf,K., see Domenjoz,R. 76,93,105 375, 419, 617, 621, 623, 624, 528,562 Moore,R.E., see Moore,R.M. 626, 628, 630-633, 637, 642, Moffat,J.G., see Ryan,J.W. 589,593,613 644,653,654 467,499,518 Moore,R.M. 589,613 Milton,A.S., see Bligh,J. 625, Mohammed,S. F., Whitworth, Moore,R.M., Moore,R.E. 629,650 C., Chuang,H.Y.K., Lund• 589,593,613 Milton,A.S., see Dascombe, blad,R.L., Mason,R.G. Moore,R.M., Singleton,A.O. M.J. 636,642,643,651 152, 198 589,593,613 Author Index 703

Moore,T.C. 359,370 Morsy,N.H., see Nakano,J. Mtiller-Eberhard, H. l, Gotze, Moore, T. e., Lawrence, W., Jr. 408,412,420 O. 428,458 359,370 Morton,D.R., see Johnson,R.A. Mtiller-Eberhard,H.J., Kunkel, Moore,T.C., Lemmi,C.A.E., 196 H.G. 426,458 Orlando, J. C., Pinkerton, W. Moses,J. M., Ebert,R.H., Mtiller-Eberhard,H.J., Lepow, 359,371 Graham, R. e., Brine, K. L. I.H. 427,428,436,458 Moore,T.C., Schayer,R.W. 112, 133 Mtiller-Eberhard,H.J., Polley, 359,371 Moses,J.M., see Graham,R.e. M.J., Calcott,M.A. 428, Moore,T.e., see Singclair,M.C. 474,477,482,511 458 359,372 Mosser,A., see Janoff,A. 286, Mtiller-Eberhard,H.J., see Moore,V., see Loew,E.R. 291 Arroyave, C. M. 434,450 14,22 Mosteller, F., see Beecher, H. K. Mtiller-Eberhard,H.l, see Moorhead,J.F., see McFarland, 601,609 Bokisch,V.A. 234,260, W. 115,132 Mosteller, F., see Smith,G.M. 428,436,440,451 Morgan,A., Robinson,L.A., 596,615 Mtiller-Eberhard,H.J., see White,T.T. 499,515 Mota,J. 17,23 Budzko,D.B. 234,260 Morgan,C., see Gocke,D.J. Mote,J.R., see Jones, T.B. 314, Mtiller-Eberhard,H.J., see 242,262 339 Cochrane,C.G. 234,241, Morgan, W.T., see Hugli,T.E. Motulsky,AG. 187,198 261,440,443,452 429,455 Mouri,T., see Abe,K. 499, Mtiller-Eberhard,H.J., see Morgan, W. T., see Kolb, W. P. 506 Gotze,O. 429,434,435,454 434,456 Movat,H.Z. 495,515 Mtiller-Eberhard,H.J., see Morganroth,J., see Strom,T.B. Movat,H.Z., Poon,M.C., Hadding,U. 434,455 306,312 Takeuchi,Y. 302,311 Mtiller-Eberhard,H.J., see Morishima, H., see Umezawa, H. Movat,H.Z., Uriuhara,T., Huber,H. 277,291,441,455 300,312 Taichman,N.S., Rowsell, Mtiller-Eberhard,H.J., see Moritz,A.R., Henriquez,F.e. H.e., Mustard,J. 183,198 Hugli,T.E. 429,455 591,613 Movat,H.Z., see Burke,J.S. Mtiller-Eberhard, H.J., see Morley,J. 314, 326, 331, 334, 270,289 335, 339, 340, 526, 554, 560, Movat,H.Z., see Habal,F.M. Hunsicker,L.G. 446, 447, 565 466,470,471,511 456 Morley,J., Bray,M.A, Gordon, Movat,H.Z., see Mustard,J.F. Mtiller-Eberhard,H.J., see D., Kennedy, W. P. 554, 559, 176,199 Johnson,A.R. 440,456 560,565 Movat,H.Z., see Ozge-Anwar, Mtiller-Eberhard,H.J., see Morley,J., Bray,M.A., Gordon, A.H. 472,516 Kolb,W.P. 434,435,456 D., Paul, W. 336, 340 Movat,H.Z., see Taichmann, Mtiller-Eberhard,H.J., see Morley,J., Dumonde,D.C., N.S. 186,202 Manni,J.A. 434,457 Wolstencroft,R.A 317,320, Mowbray,I.F. 188,198 Mtiller-Eberhard,H.I., see 331, 334,340 Mozes,E., Weinstein, Y., Medicus,R.G. 429,431,458 Morley,J., Williams, T.J. 314, Bourne, H. R., Melmon, K. L., Mtiller-Eberhard, H.J., see 319,326,340 Shearer,G.M. 358,371 Nilsson, U. 433,458 Morley,I., see Bray,M.A 320, Mtiller,B., see Habermann,E. Mtiller-Eberhard,H.J., see 325,327,332-334,336,337, 466,471,512 Podack,E.R. 434,459 554,562 Mueller,G.e., see Fisher,D.B. Mtiller-Eberhard,H.J., see Morley,J., see Dumonde,D.e. 322,338 Polley, M.J. 427,431,459 . Mueller,I.H., see Zinsser,H. 317,338 Mtiller-Eberhard,H.J., see 231,266 Morley,J., see Franco, M. 327, Ruddy,S. 446,460 Mueller,M.N., Kappas,A. 328,329,338 Mtiller-Eberhard,H.J., see 551,565 Morley,I., see Gordon,D. 324, Schreiber,R.D. 427,433, 334,338 Mtiller, P. K., McGoodwin, E. B., Martin,G.R. 219,229 461 Morley,J., see Williams, T. l Mtiller-Eberhard,H.l, see Mtiller-Eberhard,H.J. 286, 59,67, 173,205,326,342,582, Vallota,E.H. 301, 312, 345, 587 292,425,458 373,430,436,462 Morris,B., see Hall,J.G. 59, Mtiller-Eberhard,H.J., Calcott, 64 M.A 426,458 Mtiller-Eberhard,H.J., see Morrison, R. I. G., Barrett, A. J., Mtiller-Eberhard,H.J., Dal• Ward,P.A. 233,234,265 Dingle,J.T., Prior,D. 179, masso, A. P., Calcott, M. A Mtiller-Eberhard,H.J., see 198,301,311 235,263 Wuepper, K. D. 234,265 704 Author Index

Miiller-Eberhard, H.J., see Mustard,J.F., see Reimers, Nagel, E., see Bartosch,R. 13, Zimmerman, T. S. 184,205, H.J. 141,200 19 442,443,463 Mustard,M.A., see Ardlie,N.G. Nagle,.R., see Gelfand, M. C. Muggli,R., Baumgartner,H.R. 151,189 447,454 159,198 Myers,R.D., Rudy, T.A., Nagler,A. L., see Zweifach, B. W. Muggli,R., see Baumgartner, Yaksh,T.L. 621,625,654 502,522 H.R. 143,190 Myers,R. D., see Feldberg, W. Nagy,S., Redei,A., Karady,S. Muir,H., see Hardingham, T.E. 637,642,643,651 552,565 209,228 Najean, Y., Ardaillou, N., Myers,R.D., see Villablanca,J. Muir, H., see Wiebkin,O.W. Dresch, C., Bernard,1. 165, 620,655 209,230 199 Mullane,K., see Moncada,S. Myers,R.D., see Waller,M.B. Najarian,J.S., Feldman,J.D. 198 625,655 334,340 Muller, B. J., see Hunder,G.G. Nakajima,H., see Sato,H. 300, 446,456 Naccache,H.J., Showell,E. L., 312 Munder,P.G., see Fischer,H. Becker, E. L., Sha'afi, R. L. Nakano,1. 408,410,419 111,131 124,133 Nakano,J., Anggard,E., Munson,A.E., see Back,N. Nachman,R.L. 139,199 Samuelsson,B. 412,419 494,506 Nakano,1., Montague,B., Muratova,J., see Horakova,Z. Nachman,R.L., Ferris,B. 139, 199,272,292 Darrow,B. 408,419 528, 530, 532, 534, 540, 555, Nakano,J., Morsy,N.H. 408, Nachman,R.L., Weksler,B. 564 420 172,176,199 Murphy,E.A., see Evans,G. Nakano,J., Prancan,A. V. 408, 141,160,193 Nachman,R.L., Weksler,B.B., 412,420 Murphy,G.E., see Becker,C.G. Ferris, B. 176, 199 Nakayama,T., Hori,T. 630, 36,38,63 Nachman,R.L., see Weksler, 654 Murphy,P.A., Chesney,P.T., B.B. 186,187,204 Nantel,G., see Audet,A. 382, Wood, W.B., Jr. 619,654 Nadella,S.M., see Kessler,E. 415 Murphy,R.C., see Orange,R.P. 412,418 Nath, I., Poulter,L. W., 362,371 Nalf,G.B., Pensky,J., Lepow, Turk,J.L. 252,263 Murtaugh,P.M., see Gladner, 1. H. 425,458 Nathan,C.F., Karnovsky,M.L., J.A. 482,511 Nalf,G.B., Ratnoff,O.D. 426, David,J.R. 252, 263, 319, Muschel,l., see Gewurz,H. 436,458 325,340 437,454 Nalf,G.B., see Pickering,R1. Nathan, P., see Ballantyne, Mustard,J., see Movat,H.Z. D.L., Jr. 188,189 183,198 426,459 Mustard,J.F., Evans, G., Nalf,G.B., see Ratnolf,O.D. Nathan,P., see Lowenhaupt,R. Packham,M.A., Nishizawa, 449,459,469,470,517 187, 197 E.E. 172,183,198 Naff,G.B., see Westberg,N.F. Needleman, P., Bryan, B., Mustard,J.F., Glynn,M.F., 447,463 Wyche,A., Bronson,S. D., Nishizawa,E.E., Packham, Nagai, Y., see Kang,A.H. 209, Eakins,K.E., Ferrendelli,J.A., M.A. 139,198 228,302,310 Minkes,M. 154,157,199 Mustard, 1. F., Movat,H.Z., Nagaki,K., see Stroud,R.M. Needleman, P., Minkes, M., McMorine,D.R.L., Senyi,A. 427,462 Raz,A. 157,158,199 176,199 Nagasaki,M., see Ichikawa,A. Needleman, P., Moncada, S., M ustard,1. F., Packham, M. A. 554,564 Bunting,S., Vane, 1. R., 139, 140, 142, 144, 145, 151, Nagasawa,M.Y., see Suzuki,T. Hamberg, M., Samuelsson, 152, 158-161, 163-165, 172, 176,202 B. 154, 157, 199, 601,613 173, 184, 186, 199 Nagasawa,N., see Chan,J.A. Needleman, P., see Bunting,S. Mustard,J.F., see Evans,G. 390,394,395,416 155,191 141,160,193 Nagasawa,S., Shiraishi,S., Needleman,P., see Moncada,S. Mustard, 1. F., see Guccione, Stroud,R. M.- 430,458 198,613 M.A. 150,194 Nagasawa, S., see Suzuki, T. Neely,1., Davies,J.D. 98, Mustard,J.F., see Packham, 465,466,469,519 105 M.A. 151,155,161,186,187, Nagasawa,S., see Yano,M. Ne'eman, N., see Ginsburg, 1. 200 466,469,522 87,103 Mustard,J.F., see Packham, Nagayama,M., Zucker,M.B., Neher,G.M., Swenson,c.B. M.A. 172,176,186,200 Beller,F. K. 184,199 256,263 Author Index 705

Neiman-Wollners,S., see Parn• Nicholson,A., see Hammer, Noordhoek,J., Bonta,l.L. ham,M.J. 554,565 C. H. 435,455 527, 528, 530, 532, 534, 536, Nelson,D. 68,105 Nicol,P.A.E., Lachmann,P.J. 538, 539, 542, 543, 546, 565 Nelson,D.J., see Cottney,J. 430,432,458 Noordhoek,J., see Bonta,l.L. 182,192 Nicol,S. E., see Goldberg,N.D. 529, 530, 532, 534, 537, 538, Nelson,D.S. 233,263 354,368 540, 542, 543, 547, 548, 561 Nelson,D.S., Boyden,S.V. Nicolaides,E.D., De Wald, Norberg, B., see Bandmann, U. 319,340 H.A., McCarthy,D.A. 516 124,130 Nelson,N.A. 377,420 Nicolaides,E.D., De Wald, Norman,M.E., see Boyer,J.T. Nelson,R.A. 432,441,458 H.A., McCarthy,D.S. 464, 434,451 Nelson,R.A., Biro,C.E. '438, 500,516 Norman,P.S., see Bruce,C.A. 458 Nicolaides,E.D., see McCarthy, 348,366 Nelson,R.A., Jensen,J., Gigli,l., D.A. 472,514 Norman,P.S., see Steinberg,P. Tamura,N. 433,438,458 Nicolaou,K.C., see Corey,E.J. 360,373 Nelson,R.A., see Gigli,1. 426, 171,192 North,R.J. 76,105 441,454 Nicoletis,C., see Bazin,S. 223, Northover,B.J., Subramanian, Nelson,R.A., see Tamura,N. 224,227 G. 185, 199, 501, 502, 516 430,462 Nicolson,G.L., see Poste,G. Noseworthy, J., Korchak, H., Nelson,R.A., Jr. 233,263 125,f3~ Karnovsky,M.L. 113,133 Nelson,R.A., Jr., see Gigli,!. Niebyl,P.H. 1,2,4 N otkins, A. L., see Brier, A. M. 233,261 Niehaus, W.G., Samuelsson,B. 119,130 Nemerson, Y. 162,199 388,420 Notkins,A.L., see Ida,S. 351, Neri,L.L., see Salzman,E. W. Nijkamp,F. P., Flower,R.J., 369 150,201 Moncada,S., Vane,J.R. Notkins,A.L., see Snyderman, Neri,R.O., see Gordon,A.S. 412,420 R. 119,134 95, 103 Nilsson, D., Miiller-Eberhard, NovikolT,A.B. 296,311 Neta, R., Salvin, S. B. 249,263 H.J. 433,458 NovikolT,A.B., Essner,E., Neufeld,E.F., Hassid, W.Z. Nilsson, D. R., Mandle,R.J., Quintana,N. 297,311 215,229 Mcconnell-Mapes, J. A. NovikolT,A.B., see Bariand,P. Neumann,E. 7,23 428,433,458 284,288,299,307 Newball,H.H., Talamo,R.C., Nilsson,D.R., see Boyer,J.T. Nowell, P. C. 333, 340 Lichtenstein, L. M. 345, 348, 434,451 Nowell,P.C., see Pinket,M.O. 351,371 Nimni,M.E., see Deschmukh, 77,105 Newberry,W.M., see Smith, A.D. 217,228 Nugent,F. W., ZUberi,S., J.W. 323,333,341 Nishio,J., see Salvin,S.B. 324, Bulan,M.B. 467,499,516 341 Newbould,B.B. 253,263 Nugteren,D.H. 158,176,199, Newman, L. J., see Ward, P. A. Nishioka, K. 449,458 377,403-405,420 120,135 Nishizawa,E.E., Miller,W.L., Nugteren,D.H., Beerthuis, Ng,K.K.F., see McGilT,J.C. Gorman,R.R., Bundy,G.L., R. K., Dorp,D.A. van Svensson,J., Hamberg, M. 408,419 386,387,393,395,420 Nicaido,H., see Liideritz,O. 157, 175, 199 Nugteren, D. H., Hazelhof, E. 653 Nishizawa,E.E., see Evans,G. Nichols,B.A., Bainton,D.F. 141,160,193 154,199,386,388,420 72, 105 Nishizawa,E.E., see Mustard, Nugteren,D.H., see Dorp,D.A. Nichols,B.A., see Bodel,P.T. J.F. 139,172,183,198 van 384,417 72, 100 Nishizawa,E.E., see Packham, Nulsen,F.E., see Collins,W.F. Nicholson,A., Austen,K.F. M.A. 172,176,186,187,200 591,609 429,438,458 Nissen,H.M., Andersen,H. Nunn,B. 151,160,199 Nicholson, A., Brade, V., Lee, 408,420 Nurden, A. T., Caen, J. P. 166, G.D., Shin,H.S., Mayer, Nissingen,E., see Hamberg, D. 167, 199 M. M. 430,432,458 467,512 Nurminen,M., see Liideritz,O. Nicholson,A., Brade, V., Nistico,G., Mariey,E. 627 618,653 Schoriemmer, H. V., Burger, 654 N usgens, B. V., see Lenaers, A. R., Bitter-Suermann,D., Noble,R. W., Waugh,D.F. 219,229 Hadding, D. 431,433,458 120,133 Nuss,G. W., see Arman,C.G. Nicholson,A., see Brade, V. Noerjasin,B., see Mauel,J. van 480,487,488,490, 503, 235,260,429,431,451 76, 105 504,520,602,605,615 706 Author Index

Nuss,G.W., see Winter,e.M. Onabanjo,A.O., Maegraith, Ornstein,L., Janoff,A., 487,504,522 B.G. 493,516 Sweetman, F., Ansley,H. Nussenzweig, V. 441, 442, 459 O'Neill,G.J., see Wilkinson, 70,105 Nussenzweig, V., see Bianco,C. P. e. 119, 120, 125, 126, 136 Ornstein,L., see Ansley,H. 72,100 Ono,T., see Koyama,H. 306, 70,99 Nustad,K., see Amundsen,E. 310 Oro,L., see Bevegard,S. 598, 473,506 Oort,J., see Daems,W.T. 184, 609 192 Orosnky,A., Ignarro,L., Perper, Oades,Z.G., see Henson,P.M. Opferkuch, W., see Wellek,B. R. 292 270,291,304,309 434,463 Oronsky,A.L., see Perper,R.J. Oates,J.A., see Danon,A. 380, Opie, E. L. 234,263 287,292 416 Oppenheim,J.J., Elfenbein,G.J. Oshima, G., Kato,J., Erdos, Oates,J.A., see Friedman,Z. Rosenstreich,D.L. 77, 105 E.G. 473,516 159,193 Oppenheim,J.J., Seeger,R.C. Oshima, G., Sato-Omori, T., Oates,J.A., see Oelz,O. 173, 77,105 Suzuki,T. 471,516 200 Oppenheim,J.J., see Altman, Oshima, G., see Kakimoto,T. Oberdorf, A., see Hahn,F. 13, L. e. 332,337 302,310 21 Oppenheim,J.J., see Horton, Osler,A.G., see Gocke,G.J. O'Brien,J.R. 141, 147, 151, J.E. 319,330,339 442,454 153, 165, 171, 199 Oppenheim,J.J., see Rosen• Osler,A.G., see Goldstein,I.M. O'Brien,J.S. 98,105 streich,D.L. 77,106 271,290 Ocetkiewicz,A., see Oppenheim,J.J., see Wahl,S.M. Osler, A. G., see Sandberg, A. L. Gryglewski,R.J. 178, 194 119,135 118,134,461 Odake,K., see Alexander,B. Orange,R.P. 363,371 Osler, A. G., see Siraganian, 163,189 Orange,R.P., Austen,K.F. R. P. 348,372 Oddi,F., see Schultz,J. 296, 348,371 Oss,e.J. van, GiIIman,C.F. 312 Orange,R.P., Austen,W.G., 121,135 Odermatt, W. 593,613 Austen,K.F. 305,311 Oss,C.J. van, see Thrasher,S.G. Oelz,O., Oelz,R., Knapp, Orange,R. P., Kaliner,M.A., 121,134 H.R., Jr., Sweetman,B.J., Laraia, P. J., Austen, K. F. Osterland, C. K., see Spilberg, I. Oates,J.A. 173,200 305,311 490,519 Oelz,R., see Oelz,O. 173,200 Orange,R.P., Murphy,R.C., Otto,R. 12,23 Ozge-Anwar,A.H., Movat, Austen,K.F. 362,371 Outteridge, P. M., Lepper, H.Z.,Scott,J.G. 472,516 Orange,R.P., Murphy,R.C., A. W.D. 319,340 Ogawa,R., Koerten, H. K., Karnovsky, M.D., Austen, Ovary,Z., see Biozzi,G. 16, 19 Daems, W. T. 72,105 K.F. 362,371 Ovary,Z., see Bloch,K.J. 235, Ogston,D., see Ratnoff,O.D. Orange, R. P., Stechschulte, 240,260 436,459,469,470,517 D.J., Austen,K.F. 371 Owen,D.A. A. 14,23 Owen,D.A.A., Parsons,M.E. Okino,L., see Reis,M.L. 478, Orange,R.P., Valentine,M.D., 14,23 479,517 Austen,K.F. 362,371 Okudaira,T., see Ishizaka,K. Owen,D.A.A., see Parsons, Orange, R. P., see Austen, K. F. M. E. 354,371 347,369 345,348,364,366 Okamura, Y., see Shibata, N. Owren, P. A., see S tormorken, H. Orange,R.P., see Conroy,M.e. 269,293 162,202 345,363,367 Okamura, Y., see Tatsumi, N. Orange,R.P., see Kaliner,M. 124,134 348,350,363,369 Oldstone,M.B.A., see Dixon, Paalzow,L.K. 608,613 F.J. 243,261 Orange,R. P., see LaPierre,J.-G. Pace-Asciak, C. 393, 395, 396, Olgart,L., Haugertam,G., 364,370 397,420 Edwall, L. 605, 613 Orange,R.P., see Stechschulte, Pace-Asciak,e., Cole,S. 413, Oliveira, B., see Sandberg,A.L. D.J. 362,373 420 118,134,461 Oriando,J.C., see Moore,T.C. Pace-Asciak,C., Miller,D. Oliver,J.M., see Berlin,R.D. 359,371 409,420 115,130 Oriando,J.e., see Singclair, Pace-Asciak,e., Wolfe,L.S. Olsson,J. 296,311 M.C. 359,372 393,420 Onabanjo,A.O., Bhabani,A.R., Ornstein,L., Ansley,H., Pace-Asciak,C., see Coceani,F. Maegraith,B.G. 493,516 Saunders,A. 70,105 393,416 Author Index 707

Packham,M.A., Kinlough• Palmer, P., see Grant, L. H. 28, Parmley, R. T., Spicer, S. S., Rathbone, R. L., Reimers, 64 Wright,N.J. 348,371 H.J., Scott,S., Mustard,J.F. Panayi,G.S., see Dumonde, Parnham, M. J., Shoshan, S., 151, 155, 161,200 D.e. 317,338 Bonta,1.L., Neiman• Packham,M.A., Nishizawa,E. Panczenko, B., see Gryglewski, Wollners, S. 554,565 E., Mustard,1.F. 172, 176, R. J. 178, 194 Parnham,M.J., see Bonta,1.L. 186,187,200 Pantalone, R. M., Page, R. e. 554,562 Packham,M.A., see ArdJie, 278, 279, 287, 292, 325, 334, Parr, M.A., see Ringrose, P. S. N.G. 151,189 340 286,287,292 Papadimitriou, J. M., Corne• Packham, M.A., see Evans,G. Parratt,1.R. 185,200 Jisse, e. J. 69, 87, 105 141,160,193 Parratt,J.R., Sturgess,R. 185, Papadimitriou,J. M., Spector, Packham, M. A., see Guccione, 200,412,420 W.G. 69,105 M.A. 150,194 Parratt,J. R., West, G. B. 505, Papadimitriou,J.M., see Packham, M.A., see Mustard, 516,575,586 Thompson, P. L. 112, 134 J.F. 139, 140, 142, 144, 145, Parrish, M. H., see McKay, Papageorgiou, P.S., Henley, 151, 152, 158-161, 163-165, D.G. 469,514 172, 173, 183, 184, 186, 198 W.L., Glade, P.R. 320, 340 Parrott, see Wilkinson, 136 Packham, M.A., see Reimers, Papahadjopoulos,D., see Poste, Parrott, D. M. V., see Russell, H.J. 141,200 G. 125,133 R.J. 117,124,126,128,133 Page,D.A., see Dumonde, Pappenheimer, J. R., Renkin, Parry,E.H.e., see Whittle, D.e. 331,338 E. M., Borrero,L. M. 33, 66 H. e. 244,265 Page, 1. H., see Khairallah, Pappenheimer,1. R., Soto• Parsons, C. M., Goetzi, F. R. P.A. 604,605,612 Rviera,A. 33,66 531,565 Page,R.e., Davies,P., Allison, Pardo,E.G., Rodriquez,R. Parsons, E. M., see Black, J. W. A.e. 273-275,292 589, 597, 602, 605, 613 333,337,354,366 Page,R.e., see Davies, P. Pardoux,B. 2,4 Parsons, E. M., see Brimble• 272-274,289 Parish, W. E. 127, 133, 242, combe,R. W. 355, 366 Page,R.e., see Pantalone,R.M. 264,299,311,347,371 Parsons,M., see Ferreira,S.H. 278,279,287,292,325,334, Park,B.H., Good,R.A., Beck, 527,563,575,576,585 340 N.P., Davis,A.B. 305,311 Parsons,M.E., Owen,D.A.A., Paglialunga,S., see Garattini,S. Parker,C. W., Smith,J. W. 305, Ganellin,e.R., Durant,G.J. 527,528,563 311 354,371 Parker,e. W., Snider,D. E., Paintal,A.S. 591,613 Parsons, M. E., see Black, J. W. Wedner,H.J. 322, 340 Painter, R. H., see Assimeh,S. 14, 19 H. 426,450 Parker, e. W., Sullivan,T.J., Parsons, M. E., see Durant, Painter, R. H., see Ellerson,]. R. Wedner,H.J. 322, 340 G.J. 354,367 426,453 Parker,e. W., see Jakschik, Parsons,M.E., see Owen, Paiva,A.e.M., see Prado,J.L. R.A. 362,369 D.A.A. 14,23 466,517 Parker,e. W., see Smith,J. W. Parsons,M.F., see Blackwell, Palade,G.E., Bruns,R.R. 34, 306, 312, 322, 323, 333, 341 G.J. 159,178,190,400,411, 66 Parker,e. W., see Sullivan, T.J. 416 Palade,G.E., see Clementi,F. 349,373 Parsons,R.R., see Jasani,M.K. 34,63 Parker, D., see Katz,S.1. 239, 259,262 Palade,G.E., see Farquhar,M. 249,250,263,359,369 Patriarca, P., Beckerdite, S., G. 31,63 Parker, D., see Turk,J.L. 249, Elsbach, P. 382,420 Palade,G.E., see Majno,G. 9, 265 Partridge, S. M., Elsden, D. F., 22, 34, 38, 65, 475, 515, 574, Parker,J.M., see Dubas,T.e. Thomas,J. 222, 229 581,583,586 607,610 Pasteur, 7 Palester-Chlebowczyk, M., see Parker, K. L., see Sullivan, Pa trick, R. A., see Lepow, 1. H. Donati,M.B. 162,192 T.J. 349,373 345,348,351,370 Pallie, W., see Weddell,G. 592, Parkes,D.G., Eling,T.E. 393, Pasquale, N. P., de, see Burch, 615 396,420 G.E. 574, 585, 594, 609 Palmer, E., see Weddell,G. Parkinson, T. M., Schneider, Paul, W., see Morley,J. 336, 592,615 J.e. 408,420 340 Palmer, J. G., see Herring, W.B. Parkman, R., see Colten, H. R. Paul, W. E., see Benacerraf, B. 185,195 427,452 238,260 Palmer,M.A., Piper,P.J., Vane, Parmely,M.J., see Thompson, Paul, W. E., see Yoshida, T. J. R. 380,420 J.S. 352,373 317,342 708 Author Index

Paulsrud,l., see WiIlis,A.L. Pepys,M.B., Wansbrough• Peterson, M. 1., Edelman, I. S. 382,422 lones,M.H., Mirjah,D.D., 305,311 Paulsrud,l.R., MiIler,O. N., Dash,A.C. 442,459 Petit,l.M., see Lecomte,J. Schlegel, W. 414, 420 Perdue,l.F., see Kletzien,R. F. 499,514 Paulsrud,l.R., see Comai,K. 269,291 Petrin,M., see Willis,A.L. 187,191 Perdue,l.F., see Yang,Y.Z. 141, 146, 154-159, 164-166, 269,294 168, 169, 175, 178, 181, 188, Paulus, H. E., Whitehouse, 205,387,422,601,615 M. W. 558, 565 Perkins,E.S., see Eakins,K.E. 175,192 Petris, S. de, see Allison, A. C. Paupardin-Tritsch,D., see Perl,E.R. 591,613 124,129,244,260 Gerschenfeld,H.M. 361, Petruska, 1., see Hodge, A. J. 368 Perlik,F., see Kahan,A. 253, 262 218,228 Paz,R.A., Spector, W.G. 60, Perper,R., see Oronsky,A. Petz,L.D., Sharp,G.c., 66 292 Cooper,N.R., Irwin, W.S. Pearl,1.S., see Wiener,1. 51, Perper,R.l.,Oronsky,A.L. 446,459 67 287,292 Pfeiffer,C.C., see Winder,C. V. Pearsall,N.N., Weiser,R.S. Perry, A., see Persellin,R.H. 601,605,616 68, 105 551,566 Phariss,B.B., see Chasalow,F.I. Pearson, C. M. 253, 264 Perry,D.W., see Ardlie,N.G. 396,416 Peccetti, F. 523, 565 151,189 Phelps, P., McCarty,D.l., lr. Peeters,S., see Hawkins,D. Perri, T. di, Auteri,A. 448, 490,499,516 268,270,271,291 459 Phelps, P., Prockop,D.l., Pekilrek,]., Krejci,]. 317, 340 Perrin, L. H., see Theofilopoulos, McCarty,D.l. 491, 516, 589,590,600,614 Pekimk,l., see KrejCi,l. 331, A.N. 441,462 Phelps, P., see Tse,R. L. 125, 339 Perris, A.D., Whitfield,l.F. Pekarek,]., see Svejcar,l. 315, 135 497,516 Philipp-Dormston, W. K., 341 Persellin,R.H. 538,565 Siegert,R. 638, 640, 654 Pekin,T.l.,lr., Zvaifler,N.l. Persellin,R.H., Perry,A. 551, Philips, M., see Ablondi, F. B. 445,446,459 566 449,450 Pela, I. R., Gardey-Levassort, c., Persellin,R.H., see Hempel, Phillips,D.R., Agin, P. P. 152, Lechat, P., Rocha e Silva, M. K.H. 551,564 200 500,516 Persico,P., see Capasso,F. Phillips,D.R., see lenkins, Pelley,R.P., see Schwartz,H.l. 576,585 C.S.P. 139,166,196 326,341 Pert,J., see Zucker, M.B. 166, Phillips,G., see Safrit,H. 171, Pelligrino,M.A., see Dierich, 205 201 M.P. 441,453 Perutz,M.F. 200 Phillips, 1., see Snyderman, R. Pelus,L., see Davies,P. 101 Pesanti,E.L., Axline,S.G. 118, 129, 134 Pennington,D.G., see Smith, 304,311 Phillips,]. K., see Snyderman, R. M.l.H. 185,202 Peskar, B., see Glatt, M. 179, 129,134,301,312 Pennington, R., see Colwell, 1. P. 193,530,563 Picarelli,Z.P., see Henriques, 159,191 O.B. 465,469,512 Pensky,l., Hinz, C.F., lr., Peterhoff, I., see Rohen,]. W. 498,517 Pick, E. 324,340 Todd,E.W., Wedgwood, Pick, E., Feldman, T.J. 250, R.J., Boyer,].T., Lepow,I.H. Peters,D.K., WiIliams,D.G., Charlesworth,1. A., Boulton• 264 459 lones,1.M., Sissons,J.G. P., Pick, E., Krejci,J., Cech, K., Pensky,l., see Naff,G.B. 425, Turk,l.L. 239,264,326, Evans,D.l., Kourilsky,O., 458 Marel-Morage,L. 447,459 340 Pensky']., see Ratnoff,O.D. Pick,E., Mannheim,S. 317, Peters,P.D., see Skaer,R.J. 436,459,469,470,517 340 Pensky,J., see Rosen,F.S. 445, 141,201 Pick,E., Turk,1.L. 317,340 460 Petersdorf, R. c., Jr., see Pick,E., see Maillard,l.L. 239, Pepper,D.S.,lamieson,G.A. Bennet,l.L.,lr. 620, 621, 263 187,200 650 Pickering,G.W., see Lewis,T. Pepper,D.S., see Kay,A.B. Peterson,B.H., Graham,l.A., 596,612 120,132 Brooks,G.F. 434,459 Pickering,R.1., Naff,G.B., Pepys, J. 242,264 Peterson,]., see Zucker,M.B. Stroud,R.M., Good,R.A., Pepys,M.B. 442,459 141,160,205 Gewurz,H. 426,459 Author Index 709

Pickering,R.J., see Gewurz,H. Piper,P.J., see Lewis,G.P. Plotz,P.H., see Plotz,C.M. 427, 446,454 178,197 533,566 Pickering,R.J., see Shin,H.S. Piper,P.J., see Palmer,M.A. Pluznik,D.H., Sachs,L. 93, 433,434,461 380,420 105 Pickering,R.J., see Stroud,R.M. Piper,R., Vane,J.R. 181,200 Pochin, E. E., see Lewis, T. 590, 427,462 Pirquet,C. von 231,264 612 Pickles, V. R., see Clegg, P. C. Pirquet,c. von, Schick,B. Podack,E.R., Kolb,W.P., 604,605,609 231,264 Miiller-Eberhard,H.J. 434, Picton,N., see Curtis,A.S.G. Pirquet, C. von, Scick, B. 12, 459 111,131 23 Pogo,B.G.T., Allfrey,V,G., Pierce,C.W., Kapp,J.A. 76, Pisano,J., Webster,M. 18, 23 Mirsky,A.E. 323,340 105 Pisano,J.J. 465,467,516 Polak,L., Geleick,H., Turk,J.L. 250,264 ·Pierce,J.V. 467,470,516 Pisano,J.J., Austen, K. F. 465, Polak,L., Turk,l.L. 236, 246, Pierce,J.V., Webster,M.E. 472,516 250,264 464-466,469,516 Pittman,Q.J., Veale,W.L., Polasek,J., Kubisz, P. 177,200 Pierce, J . V., see Guimiires, J . A. Cooper,K.E. 621, 626, 647, Pollard,J., Flower,R.J. 402, 466,511 654 421 Pierce,J.V., see Webster,M.E. Plageman,P.G.W., see Pollard, T .D., see Stossel, T. 466,469,471,472,520,521 Estensen,R.D. 269,290 Pietra, G .G., Szidon, J . P., 124,134,269,293 Platt-Mills, T.A.E., Ishizaka,K. Leventhal,M.M. 38,66 Poller,L., see Sear,C.H.J. 432,459 Piez,K., Lewis,M.S., Martin, Plaut,M. 358,362,365,371 177,201 G.R., Gross,J. 216,229 Polley,H.F., see Hench, P.S. Piez,K.A., Eigner,E.A., Plaut,M., Berman,U. 358, 550,564 Lewis,M.S. 229 371 Polley,K.J., see Ross,G.D. Plaut,M., Lichtenstein,L.M. Piez, K .A., see Bornstein, P. 441,460 218,227 345 Polley,M.J., Miiller-Eberhard, Piez, K .A., see Kang,A. H. 209, Plaut,M., Lichtenstein,L.M., H.J. 427,431,459 Gillespie,E., Henney,C.S. 217,228,302,310 Polley,M.J., see Huber,H. 356, 357, 359, 371 Piez, K.A., see Traub, W. 217, 277,291,441,455 Plaut,M., Lichtenstein,L.M., 230 Polley,M.J., see Miiller-Eber• Henney,C.S. 356, 357, 371 Pignaud,G., see Legrande, Y. hard,HJ. 428,448,458 Plaut, M., see Roszkowski, W. 272,292 Polyzonis, M., see Davies, P. Pike,J .E., Kupiecki,F .P., 356, 358,372 270,289 Weeks,J .R. 410,420 Pless,H.H., see Arman,C.G. Pond man, K. W., see Ter Laan, Pike,J.E., see Daniels, E.G. van 480, 487, 502, 504, 520, B. 440,462 393,416 576,586 Ponsford,J.R., see Kirby,P.J. Pillemer,L., Blum,L., Lepow, Pless,J., Stiirmer,E., Gutmann, 336,339 I.H., Ross,O.A., Todd,E.W., S., Boissonnas,R.A. 464, Pontieri, V., see Moncada,S. Wardlaw,A.C. 235, 264, 516 601,613 428,432,459 Pless,J., see Boissonas,R.A. Poole,A.R., Barratt,M.E.J., Pinkerton, W., see Moore, T. C 464,507 Fell,H.B. 284,285,292 359,371 Pletscher,A. 141,200 Pinket,M.O., Cowdrey,C.M., Pletscher,A., Bartholini, G., Poole,A.R., Hembry,R.M., Nowell, P.c. 77, 105 Da Prada,M. 141,200 Dingle,J.T. 283,292 Pinnell,S.R., see Krane,S.M. Pletscher,A., Burkard, W. P., Poole,A.R., see Dingle,J.T. 220,229 Tranzer,J.P., Gey,K.F. 283, 285, 286, 290, 300, 308 Piper,P.J., Collier,H.O.J., 141,200 Poole,A.R., see Millroy,S.J. Vane,J.R. 555,566 Pletscher, A., Da Prada, M., 285,292 Piper,PJ., Vane,J.R. 157, Bartholini,G. 141,200 Poon,M.C., see Movat,H.Z. 200, 377, 390, 392, 409, 421, Pletscher,A., Da Prada,M., 302,311 488, 516, 597, 598, 601, 606, Berneis,K.H. 141,200 Popieraitis, A.A., Thompson, 614,631,654 Pletscher,A., see Da Prada,M. A.G. 499,516 Piper,P.J., Vane,J.R., Wyllie, 141,192 Porter, K.A. 187,200 J.H. 409,421 Plotz,C.M., Plotz,P.H., Porter,R.R., see Reid,K.B.M. Piper, P.l., see Crutchley,D.l Lamont-Havers,R.W. 533, 426,459 413,414,416 566 Portier, P., Richet, C. 12, 23 710 Author Index

Portoghese,P.S., Svanborg,K., Press,M., Hartop,J.P., Quie,P.G., see Estensen,R.D. Samuelsson,B. 401,421 Hawkey,C. 168,172,200 125,131 Poskitt,T.R., Fortwengler, Pressman, B.C., see De Duve, e. Quie,P.G., see Gallin,J.1. H.P., Jr., Lunskis,B. 432, 482,508 136 459 Preston, P. M., see Dumonde, Quie,P.G., see Hill,H.R. 356, Posner,J., see Bennet,A. 632, D.C. 77,101 357,369 650 Pringle,E.M., see Barott,H.G. Quijada,L., see Contreras,E. Poste, G., Papahadjopoulos, D., 627,649 608,609 Nicolson,G.L. 125, 133 Prior,D., see Morrison,R.I.G. Quintana, C., see Barnhart, M.1. Potter,D.E., see McCarthy, 179,198,301,311 299,307 D.A. 472,514 Prior,J.C., see Stretten,D.H.P. Quintana,N., see Novikolf, Potter,G.D., Guzman, F., Lim, 500,519 A.B. 297,311 R.K.S. 593,614 Prockop,D.J. 220,229 Qureshi,M.e., see Tomlinson, Potter,G.D., see Guzman,F. Prockop,D.J., see Bhatnagar, R. V. 203, 396,422 16, 17,21, 501,511,603,611 R.S. 216,227 Potts, W .J. 632,654 Prockop, D.J., see Cooper, Potts, W.J., East, P.F. 626, G.W. 220,227 Rabelline,E.M., see Ross,G. D 627,635,654 Prockop,D.J., see Dehm,P. 441,460 Poulter,L.W., see Nath,1. 252, 218,228 Rabinovitch, M. 76, 105 263 Prockop,D.J., see Grant,M.E. Rabson,A.R., see Alper,C.A. Poulter,L.W., see Turk,J.L. 211,228 430,441,442,450 249,265 Prockop,D.J., see Jimenez,S.A. Raby,C., see Hureau,J. 499, Pounder,R.E., Hunt,H.R., 221,228 513 Stekelman,R., Milton• Prockop,D.J., see Phelps, P. Rachmilewitz, M., Schlesinger, Thompson,G.J., Misiewicz, 491, 516, 589, 590, 600, 614 M. 76,106 J.J. 355,371 Prockop,D.J., see Schofield, Raepple,E., Hill,H. U., Powell,J.R., Brody,M.J. 355, J.D. 218,230 Loos, M. 448, 449, 459 372 Propp,R.P., see Alper,C.A. Rafelson,B.R., see Legrand, Y.J. Powers, S .R., Brown, H. H., 429,450 179,197 Stein,A. 499,516 Proulx,P., see Audet,A. 382, Rafelson,L.R., see Legrand, Y.J. Prado,E.S., see Guimiires,J.A. 415 179,197 466,511 Pruitt,K.M., see Boackle,R.J. Rafelson,M.E., see Booyse, Prado,E.S., see Prado,J.L. 451 F.M. 139,142,190 466,471,517 Pryce-Jones,R.H., Wood,G.C. Rafelson,M.E., see Legrande, Prado,J. L. 471,516 302,311 Y. 272,292 Prado,J.L., Limiios,E.A., Puig Muset,P., Puig Parellada, Rafter,G.W., Collins,R.D., Roblero,J., Freitas,J.O., P., Martin Esteve,J. 608, Wood, W.B., Jr. 619, 654 Prado,E.S., Paiva,A.C.M. 614 Raisz,L.G., see Horton,J.E. 466,517 Puig Parellada, P., see Puig 319,330,339 Prado,J.L., Mendes,J, Rosa, Muset,P. 608,614 Raizes,G.S., see Joyner,W.L. R.C. 471,517 Pullinger,B.D., Florey,H.W. 583,586 Prado, J. L., Monier, R., Prado, 58,66 Ramachandran,G.N. 216, E.S., Fromageot,C. 471, Puls,J.L., see White,T.G. 255, 229 517 265 Ramalho-Pinto,F.J., see Prado,J.L., see Borges,D.R. Purcell,G.M., Barnhart,M.J. Camargo,A.C.M. 466, 473, 466,507 301,311 507 Prado,J.L., see Guirniires,J.A. Purchert, I., see Morsdorf, K. Ramos,A.O., see Chapman, 466,511 482,515 L.F. 492, 507, 594, 595, 609 Praga,C., Valentine,L., Puszkin, E., Puszkin, S., Ramsey,F.R., see Roberts,E.D. Maiorano, M., Cortellaro, M. Aledort,L.M. 140,200 256,264 164,200 Puszkin,S., see Puszkin,E. Ramsey,W.S. 113,117,133 Prakash,A., see Greenbaum, 140,200 Ramsey, W.S., Harris,H. 114, L.M. 309 133 Prancan,A.V., see Nakano,J. Quentin,B., see Laden,C. 529, Rilmwell,P.W., Shaw,J.E. 408,412,420 533-536,538,540,565 383,421,607,614 Pras,M., Glynn,L.E. 221, Quie,P.G., see Becker,E.L. Ramwell,P.W., Shaw,J.E., 229 124,130 Jessup,R. 607,614 Prausnitz,C., Kiistner,H. Quie,P.G., see Davies,A.T. Ramwell,P.W., see Dawson, W. 346,372 290 408,416 Author Index 711

Ramwell,P.W., see Johnson,M. Reaven,E.P., see Axline,S.G. Remold,H.G., see Remold• 139, 142, 175, 196 269,288 O'Donnell,E. 324,341 Ramwell,P.W., see Shio,H. Rebuck,J.W., Crowley,J.H. Remold,H.G., see Ward,P.A. 156,181,201 259,264 118, 135, 319, 328, 332, 341 Ramwell,P.W., see Willis,A.L. Recklinghausen,F.D.V. 7,23 Remold-O'Donnell, E. 356, 153, 168, 170, 175, 177, 205, Redei,A., see Nagy,s. 552,565 358,372 627,631,645,646,655 Rees,R.J.W., see Gaugas,J.M. Remold-O'Donnell, E., Remold, Ranadive, N. S., Cochrane, e. G. 529,545,563 H.G. 324,341 302,311 Rees,R.J.W., see Godal,T. Renfrew,A.G., see Erdos,E.G. Randall,L.O. 602,603,614 251,262 473,509 Randall, L. 0., Selitto,1.J. Rees,R.J.W., see Wemambu, Renkin, E. M. 33, 66, 583, 586 589,597,602,606,614 S.N.e. 242,265 Renkin,E.M., Carter,R.D., Ranvier,L., see Cornil, V. 7,20 Reich,E. 273,286,287,292 Joyner, W.L. 583, 586 Rao,G.N.R., see Gerrard,J.M. Reich, E., see Unkeless,J.e. Renkin,E.M., see Pappen• 140, 155, 170, 171, 179, 193 281,293 heimer,1 .R. 33, 66 Rapp,H.J. 362,372 Reid,K.B.M. 426,459 Renkin,G.M., see Joyner,W.L. Rapp,H.J., see Borsos,T. 425, Reid,K.B.M., Porter,R.R 583,586 427,428,436,451 426,459 Rent,R., Ertel,N., Eisenstein, Rapp,H.J., see Colten,H.R Reid,K.B.M., Lowe,D.M., R., Gewurz,H. 425, 460 427,452 Porter,RR. 426,459 Renz, P., see Luckner,G. 411, Rappaport,H. 99,106 Reid,K.B.M., Doyle,B.B., 419 Repin, I.S., Kratskin, I. L. 620, Rassaert, G., see Di Pasquale,G. Leonard, K. 426,460 654 553,562 Reimers,H.J., Allen,D.J., Reuse,J .J. 183,201 Rather, L. J. 2,4 Feuerstein,A., Mustard,J.F. Reuter,H., see McNicol,G.P. Ratnoff, O. D. 172,200 141,200 143,197 Ratnoff,O.D., Miles,A.A. Reimers,H.J., Mustard,J.F., Revak,S.D., see Cochrane,C.G. 471,517 Packham, M.A. 141,200 472,507 Ratnoff,O.D., Naff,G.B. 449, Reimers, H. J., Packham, M. A., Rex,R.D., see Clark,E.R. 459 Mustard,J.F. 141,200 49,51,53,55,63 Ratnoff,O.D., Pensky,1., Reimers,H.J., see Packham, Reynolds,J.J., see Harris, Ogston,D., Naff,G.B. 436, M.A. 151, 155, 161,200 E.D., Jr. 281,291 459,469,470,517 Reis,M.L., Medeiros,M.e., Reynold,1 .1., see Werb,Z. Ratnoff,O.D., see Davie,E.W. Rocha e Silva,M. 471,517 281,294 211,227 Reis,M.L., Okino,L., Rocha Rich,A., Lewis,M.R. 315,341 Ratnoff,O.D., see Donaldson, eSilva,M. 478,479,517 Richards, W.H.G. 492, 517 V.H.G. 440,453 Reis, M.L., see Corrado,A.P. Richards,W.H.G., see Good- Ratnoff,O.D., see Graham,R.C. 467,508 win, L.G. 485,492,511 474,477, 482, 511 Reis,M.L., see Diniz,C.R. Richerson, B.B., Dvorak, H.F., Ratnoff,O.D., see Naff,G.B. 467,468,499,508 Leskowitz,S. 314,341 426,436,458 Reis, M .L., see Rocha e Silva, Richerson,H.B., Dvorak,H.F., Ratnoff,O.D., see Webster, M. 471, 489, 517, 532, 536, Leskowitz,S. 264 M.E. 471,521 566 Richet, e., see Portier, P. 12, Rauterberg,E.W., Gebest,H.J. Reis,M.L., see Sampaio,M. U. 23 435,459 465,518 Richter,R., see Di Pasqulae,G. Rawlins, M.D., see Cranston, Reisfeld,R.A., see Dierich,M.P. 553,562 W.I. 621,640,641,648,651 441,453 Riddle, J. M., see Barnhart, M. I. Raz,A., Schwartzman,M., Remington,J.S., Krahenbuhl, 299,307 Gafni, Y., Kenig-Wakshal,R. J.L., Hibbs,J.B. 77,106 Rienits,K.G. 216,229 394, 400,421 Remold,H.G., Katz, A.B., Riesterer, L., Jaques, R. 556, Raz,A., see Moncada,S. 198 Haber,E., David,J.R. 331, 566 Raz,A., see Needleman, P. 157, 340 Rietschel, E. T., Gottert, H., 158, 199 Remold,H.G., Ward,P., Liideritz,O., Westphal, O. Reaburn,J.A., see Furth,R. David,J.R. 340 618,654 van 72,102 Remold,H.G., see Coyne,1.A. Rietschel, E. T., see Gaianos, C. Ream, V.J., Deykin,D., 337 618,652 Gurewich, V., Wessler,S. Remold,H.G., see David,J.R. Rietschei,E.T., see Liideritz,O. 184,200 76,101 618,653 Reaven,E.P., Axline,S.G. Remold,H.G., see Meyers,O.L. Riggild,D.A., see Brown,J.H. 114,124,133 331,339 555,556,562 712 Author Index

Riggs,S., see Sharp,J .T. 256, Robertson,B.S., see Schwab, Rocha e Silva, M. 6, 13-17, 19, 264 J.H. 273,293 23, 352, 372, 465, 469, 474, Righby,C.C., see Trapnell,J.E. Robertson, P.B., Ryel,R. B., 517, 524, 555, 566, 594, 614 500,520 Taylor,R.E., Shyn,K.W., Rocha e Silva, M., Antonio, A. Riley,J .F. 347,372 Fullmer,H.M. 302,311 17,23,484,504,505,517,582, Riley,J.F., West,G.B. 572,586- Ro bert son, P. B., Shru, K. W., 586 Rindani, T .H. 527, 537, 540, Vail,M.S., Taylor,R.E., Rocha e Silva, M., Aronson, M. 566 Fullmer,H.M. 280,293 13,23,24 Rindler-Ludwig,R., see Dewald, Robertson, W., Schwartz, B. Rocha e Silva, M., Beraldo, B. 268, 270, 290 van 275,293 W.T. 23 Ringold,H.J., see Tomlinson, Robineaux,R.113,133 Rocha e Silva, M., Beraldo, R.V. 203,396,422 Robineaux,R., Frederic,J. W.T., Rosenfeld,G. 16, 23, 464,465,471,517 Ringrose,P.S., Parr,M.A., 113,133 Rocha e Silva,M., Bier,O.G. McLaren, M. 286, 287, 292 Robineaux,R., see Frederic,J. 15,24 Risley,E.A., see Arman,C.G. 113,131 Rocha e Silva, M., Bier,O.G., van 490,504,520 Robineaux,R., see Weissman,G. Aronson,M. 13,24 Risley,E.A., see Winter,C.A. 18,25, 306,313 Robins,S.P., see Bailey,A.J. Rocha e Silva, M., Cava1canti, 487,504,522 R.Q., Reiss,M.L. 498,517, Rita, G .A., see Davies, P. 268, 217,227 Robinson,B., see Collier,J.G. 532,536,566 289,301,308 Rocha e Silva, M., Dragstedt, Rita,G.A., see Weissmann,G. 598,609 Robinson,B.V., Robson,J.M. C.A. 15,16,20,24 551,567 Rocha e Silva, M., Garcia-Leme, Ritts,R.E., see Crout,J.E. 333, 529-531, 533, 536-538, 540, 545,566 J. 11, 17, 24, 500, 501, 504, 337 517,551,566,594,614 Rivers,J.P. W., Hassam,A.G. Robinson,B. V., see Billingham, M.E.J. 539, 542, 545, 547, Rocha e Silva,M., Leme,G.J. 172,201 548,561 95, 106 Rivkin, I., Rosenblatt, J., Robinson,D. R., see Kantrowitz, Rocha e Silva,M., Reis,M.L., Becker,E.L. 125, 133 F. 178,196 Ferreira,S.H. 471,517 Rixon,R.H., Whitfield,J.F., Rocha e Silva, M., Rosenthal, Robinson,J. A., see Barnhardt, Bayliss,J. 497,517 S.R. 486,517,572,586 M.1. 143,189 Rixon,R.H., see Whitfield,J. F. Rocha e Silva, M., Rothschild, 322, 341, 497, 517 Robinson,L.A., see Morgan,A. H.A. 17,18,24 Rizack, M. A., see Elsbach, P. 499,515 Rocha e Silva, M., see Andrade, 177,192 Robinson, P. G., see Samuels, S.O. 16,19 Robb,I.A., see Mills,D.C.B. C.E. 168,172,201 Rocha e Silva, M., see Bier, 146, 158, 178, 198, 272, 292 Ro binson, V. B., see Billingham, O.G. 15,16,19 Robb-Smith,A.H.T. 99, 106 M.E.J. 533, 537, 538, 540, Rocha e Silva,M., see Diniz, Robb-Smith,A.H. T., see 542,544,545,548,561 C.R. 465,508 Scott,R.B. 99,106 Roblero,J., see Prado,J.L. Rocha e Silva, M., see Ferreira, Robert,B., see Legrande, Y. 466,517 S.H. 473,503,510 272,292 Roblero,J., see Ryan,J. W. Rocha e Silva, M., see Garcia Robert,L., see Legrande, Y. 473,518 Leme,J. 466, 467, 475, 482, 272,292 Robson,J.B., see Billingham, 483-485, 487, 489, 497, 501, Roberts,E.D., Switzer,W.P., M.E.J. 533, 537, 538, 540, 502,504,505,510 Ramsey, F. R. 256, 264 542,544,545,548,561 Rocha e Silva, M., see Hamberg, Roberts,G.C.K., see Mills, Robson,J.M., see Billingham, U. 465,473,512 D.C.B. 146, 152, 158, 178, M.E.J. 533, 537, 540, 542, Rocha e Silva, M., see Pela, I. R. 198,272,292 545, 548,561 500,516 Roberts,H.R., see Saba,H. Robson). M., see Cygielman, S. Rocha e Silva, M., see Reis, 303,311 529, 530, 531, 533, 535, 540, M.L. 471,478,479,517 Roberts,J.A., see Wilkinson, 562 Rocha e Silva, M., see Ryan,J. P.c. 119,120,125,126,136 Robson,J. M., see Robinson, W. 478,518 Roberts,J.M., see Jasani,M.K. B.V. 529-531,533,536-538, Rocha e Silva, M., see Souza, 259,262 540, 545, 566 J.M. 485,519 Roberts, W.C., Sjoerdsma,A. Robson,R.T., see Waddell, Rocha e Silva, M., see Vugman, 225,229 A. W. 111, 135 I. 573,587 Author Index 713

Rocklin,R.E. 319, 321, 332, Rosa, A. T., Rothschild, Z., Rosendorff,C., see Woolf,C.J. 341,356,358,360,372 Rothschild,A.M. 469,517 631,635,636,656 Rocklin,R.E., MacDermott, Rosa, A. T., see Rothschild, Z. Rosenfeld, G., see Rocha e Silva, R.P., Chess,L., Schlossman, 518 M. 16,23,464,465,471,517 S.E., David,J.R. 332,341 Rosa,M.di, see Capasso,F. Rosenfeld, G., see Spanoudis,S. Rocklin, R. E., Meyers, 0 .L., 576,585 236,264 David,J.R. 321,341 Rosa,R.C., see Prado,J.L. Rosenfeld,S.I., Kelly,M.E., Roden,L., Smith,R. 215, 229 471,517 Baum,J., Leddy,J. P. 433, Roden,P. von, see Werle,E. Rose,A.J., Collins,A.J. 396, 445,460 470,521 398,421 Rosenfeld,S.I., Ruddy,S., Rodgers,D. W., see Dickerson, Rose,B. 13,24 Austen,K.F. 427,460 G.D. 591,610 Rose,N.R., see Thrasher,S.G. Rosenfe1der,G., see Liideritz, Rodgers,D.W., see Guzman,F. 121, 134 O. 618,653 501, 5ft, 603, 6ft Roseman,S. 110,133 Rosengren,E., see Kahlson,G. Rodgers,D.W., see Lim,R.K.S. Rosen, F .S., Charache, P., 353,369 22, 481, 501, 514, 589, 590, Pensky,J., Donaldson, V. Rosenstreich,D.L., Oppenheim, 594,600,603,612,613 445,460 J.J. 77,106 Rodman,N.F. 185,201 Rosen,F.S., see Abramson,N. Rosenstreich,D.L., see Oppen• Rodman,N.F., Mason,R.G. 445,450 heim,J.J. 77,105 163,201 Rosen,F.S., see Alper,C.A. Rosenstreich,D.L., see Wahl, Rodrick, M. L., see Knobal, 429, 430, 432, 441, 442, 447, S.M. 333,341 H.R. 426,456 450 Rosenthal,A.S., Lipsky,P.E., Rodriquez,R., see Pardo, E.G. Rosen,F.S., see Donaldson, Shevach,E.M. 76, 106 589,597,602,605,613 V.H.G. 439,440,453 Rosenthal,A.S., Thomas Blake, J., Ellner,J.J., Greineder, Roesler, G., see Hesse,E. 589, Rosen,F.S., see Einstein,L.P. 597,602,611 428,429,453 O.K., Lipsky,P.E. 77,106 Rosenthal,A.S., see BaJow,J.E. Rogers,D.E. 497,517 Rosen,F.S., see Gitlin,J.D. 428,454 287,288,333,337 Rogers,D.W., see Guzman,F. Rosen,F.S., see Johnston,R.B, Rosenthal,A.S., see Gallin,J. I. 16,17,21 Jr. 432,456 124,125,131 Rogers,J., see Weiss,H.J. 166, Rosen,F .S., see Klemperer, Rosenthal,R.R., see Bruce,C.A. 169,204 M.R. 428,456 348,366 Rohen,J .W., Peterhoff,I. Rosen,F.S., see Lepow,I.H. Rosenthal,S.R. 593, 614 498,517 345,348,351,370 Rosenthal,S.R., Minard,D. Rohen,J.W., see Haberland, Rosen,F.S., see Sheffer,A.L. 480,518 G.L. 469,511 439,449,461 Rosenthal,S.R., see Rocha e Rohloff,N., see Glenn,E.P. Rosen,F.S., see Ziegler,J.B. Silva,M. 486, 517, 572, 586 254,262 430,463 Rosenthale,M.E., Dervinis,A., Rohloff, N., see Glenn, M. E. Rosenau,M.J., Anderson,J.F. Kassarich,1. 186,201 553,563 12,24 Rosenthale,M.E., Dervinis,A., Rome,L.H., see Lands,W.E.M. Rosenberg,L., Hellman,W., Massarich,J., Singer,S. 598, 400,419 Kleineschmidt,A.K. 215, 614 Romeo,D., see Rossi,F. 76, 229 Rosenthale,M.E., Kassarich,J., 106 Rosenberg,R., see Janoff,A. Schneider, F., Jr. 605, 614 Rommel, F. A., Goldlust, M. B., 281,291 Rosiere,C.E., see Winder,C.V. Bancroft,F .C., Mayer, Rosenberg,R., see Lahiri,B. 531,567 M.M., Tashjian,A.H. 434, 469,470,514 Ross,G.D., Jensen,J.A. 437, 460 Rosenberg,S.A., see Coyne,J.A. 460 Rommel,F.A., Mayer,M.M. 337 Ross,G.D., Polley, K. J., 435,460 Rosenblatt,J., see Rivkin,I. Rabelline,E.M., Grey,H.M. Rona,G., see Gabbiani,G. 125,133 441,460 36,64 Rosendorlf,C., Mooney,J.J. Ross,L.L., see Gershorn,M.D. Rooney, P.J., Hayes,J.R., 620,621,646,648,654 361,368 Webb,J., Lee, P., Carson, Rosendorlf,C., see Cranston, Ross,O., see Pillemer,L. 235, R.W. 544,566 W.I. 621,640,651 264 Root,R.K., Ellman,L., Frank, Rosendorff,C., see Laburn,H.P. Ross,O.A., see Pillemer,L. M. M. 432,460 633,635,636,653 428,432,459 714 Author Index

Ross, R. 213,229 Rothschild,H.A., see Rocha e Ruddy,S., see Fearon,D.T. Ross,R., Benditt,E.P. 220, Silva,M. 17,18,24 429, 431, 433, 436, 448, 453 229 Rothschild, P., see Lewis, T. Ruddy,S., see Gigli,I. 426,454 Ross,R., Klebanoff,S.J. 211, 596,612 Ruddy,S., see Goldman,lN. 214,229 Rothschild,Z., Rosa,A.T., 434,455 Ross, R., see Ehrlich, H. P. 220, Rothschild,A.M. 518 Ruddy,S., see Hunsicker,L.G. 228 Rothschild, Z., see Rosa, A. T. 446, 447,456 Ross, R., see Leibovich, S. l 469,517 Ruddy, S., see Rosenfeld, S. I. 74, 104 Rothstein,G., Hiigl,E.H., 427,460 Rosse, W.F., Logue,G.L., Bishop,e.R., Athens,J. W., Ruddy,S., see Whaley,K. 430, Silberman,H.R., Frank, Ashenbrucker,H.E. 95,106 463 M.M. 449,460 Rothstein,G., Hiigl,E.H., Rudy,T.A., Viswanathan,e.T. Rossi,E.e. 151,201 Chervenick, P.A., Athens, 626,634,654 Rossi, F., Zabucchi,G., Romeo, J.W., Macfarlane,}. 106 Rudy,T.A., see Myers,R.D. D. 76,106 Rous, P., Gilding,H. P., Smith,F. 621,625,654 Roswell,H.e., see Movat,H.Z. 34,66 Rudy, T.A., see Vishwanathan, 183, 198 Rowlands,D. T., Jr., see Ilgen, C. T. 634,655 Roszkowski, W., Plaut,M., e. L. 427, 456 Riihl,H., Vogt, W., Bochert,G., Lichtenstein,L. M. 356, Rowley, D., Howard,J.G., Schmidt, S., Moelle, R., 358,372 Jenkin,e.R. 621,654 Schaoua,H. 119,133 Roth,G.J., Majerus,P.W. 179, Rowley,D.A. 38,66 Ruggeri,Z. M., see Mannucci, 201 Rowley, D. A., Benditt, E. P. 15, P.M. 166,197 Roth,G.J., Stanford, D., 24 Rugstad,H.D., see Gautvik, Majerus, P. W. 179, 201 Roy,A.e., see Collier,H.O.J. K.M. 467,511 Roth,G.J., Stanford, N., 607,609 Rugstad,H.E. 473,518 Majerus, P. W. 383, 421 Rozmanith,J. S., see Satake, K. Rugstad, H. E., see Amundsen, E. Rother, K. 441,460 499,518 492,506 Rother, K., Rother, U., Rubin, P., see Blatt, I. M. 99, Ruscetti, F. W., Chervenick, Schinders, F. 443, 460 100 P.A. 76,93,106 Rother, K., see Rother, U. 434, Rubin,R.H., see Lewis,R.A. Russell, see Wilkinson 136 460 348, 350,370 Russell,R.l, McInroy,R.J., Rother, U., Rother,K. 434, Rudas, B., Stoklaska, E. 528, Wilkinson,P.C., White,R.G. 460 529,531,533,566 120,133 Rother,U., Thorbecke,G.J., Ruddle, N. H., Waxman, B. H. Russell, R. J., Wilkinson, P. e., Stecher-Levin, V.J., Hurli• 279,293 McInroy,R.J., McKay,S., mann,J., Rother, K. 434, Ruddy,S., Austen, K. F. 428, McCartney,A.e., Arbuth• 460 430,446,460 nott, l P. 120, 133 Rother, U., see Rother, K. 443, Ruddy,S., Austen,K.F., Russell,R.J., Wilkinson, P.e., 460 Siess, F., Parrott, D. M. V. Rothman, P., see Breslow,l Goetzl,E.J. 441,460 117, 124, 126, 128, 133 434,451 Ruddy, S., Carpenter, e. B., Russell,R.J., see Wilkinson, P. C. Rothschild,A.M. 467,495, Chin,K.W., Knostman,lN., 120,136 518 Soter,N.A., Giitze, 0., Rothschild,A. M., Castania, A., Miiller-Eberhard, H. J., Ruthven,e.R.J., Sandler,M. 467,471,487,518 Austen, K. F. 446, 460 403,421 Rothschild,A. M., Castania, A., Ruddy,S., Everson,L.K., Rutstein,J.A., see Green,J. A. Cordeiro,R.S.B. 496, 518 Schur, P. H., Austen, K. F. 319,330,338 Rothschild,A. M., Cordeiro, 446,460 Ryan,G.B. 60,66 R.S.B., Castania,A. 497, Ruddy,S., Fearon,D.T., Ryan,G.B., Borysenko,J.Z., 518 Austen,K.F. 446,447,460, Karnovsky,M.l 115, 134 Rothschild, A. M., Gascon, L. A. 461 Ryan,G.B., Hurley,lV. 47, 467,487,489,518 Ruddy,S., Gigli,I., Austen,K.F. 66,129,134 Rothschild, A. M., see Castania, 271,293 Ryan,G.B., Spector,W.G. A. 469,507 Ruddy,S., Gigli,I., Sheffer,A.L, 87, 106 Rothschild, A. M., see Rosa, A. T. Austen,K.F. 439,460 Ryan, G. B., see Buckley, I. K. 469,517 Ruddy,S., see Bach,S. 427,450 38,63 Rothschild,A. M., see Roth• Ruddy,S., see Caldwell,J.R. Ryan,G.B., see Gabbiani,G. schild,Z. 518 438,439,451 210,228 Author Index 715

Ryan,G.B., see Hurley,J.Y. Salvin,S.B., see Neta,R. 249, Samueisson, B., see Portoghese, 42,46,47,60,62,64 263 P.S. 401,421 Ryan,G.B., see Joris,!. 36,65 Salzman,E.W. 139,147,150, Samuelsson,B., see Svensson,J. Ryan,G.B., see Majno,G. 36, 153, 156, 165,201 157,202,601,615 38,65 Salzman, E. W., Chambers, D.A, Samuelsson,B., see Wlodawer, Ryan, G. B., see Spector, W. G. Neri,L.L. 150,201 P. 386,387,394,422 87,107 Sampaio,C., Wong,S.C., Show, Sandberg,A.L., Oliveira, B., Ryan,G.B., see Stecher, V.J. E. 470,518 Osler,A.G. 118, 134, 461 120, 134, 176,202 Sampaio,M.U., Reis,M.L., Sandberg,A.L., see Koopman, Ryan,G.B., see Willoughby, Fink,E., Camargo,A.C.M., W.J. 442,456 D.A. 252,265 Greene,J.L. 465, 518 Sander,G.E., Huggins,C.G. Ryan,J., see Diniz,C.R. 465, Samter,M., Czarny,P. 347, 465,518 508 348,372 Sanders,A.G., see Grant,L.H. Ryan,J. W., Moffat,J.G., Samuei,S. 10,24 28,64 Thompson,A.G. 467, 499, Samuels,C.E., Robinson,P.G., Sandhaus,R.A., see Janoff,A. 518 Elliot,R.B. 168, 172,201 286,291, 300, 311 Ryan,J. W., Robiero,J., Stewart, Samuelsson,B. 377, 384, 394, Sandhoff, K" Harzer, K. 98, J.M. 473,518 395,408,421 106 Ryan,J.W., Rocha e Silva,M. Samuelsson, B., Granstrom, E., Sandler,J.A., see Clark,R.A.F. 478,518 Green, K., Hamberg, M. 356, 357,367 Ryder,G., see Cream,J.J. 242, 405, 408, 411 Sandler,M., see Ruthven,C.R.J. 403,421 261 Samuelsson, B., Grandstrom, E., Sandrin,E., see Boissonas,R.A. Rydgren, L., see Bandmann, U. Hamberg, M. 394, 421 464,507 124,130 Samuelsson,B., Green,K. 402, Sanford, C. H., see Goldberg, Ryel,R.B., see Robertson,P.B. 421 N.D. 354,368 302,311 Samuelsson, B., Hamberg, M. Sangostino,A., see Ferri,S. 388,421 608,610 Saavadra, J. M., Brownstein, Samuelsson, B., see Anggiird, E. Sanner,J.H. 632,654 M., Axelrod,J. 352, 372 384,406,408-410,415 Saba,H., Roberts,H.R., Herion, Santi,D.V., see Lin,S 269, Samuelsson, B., see Bergstrom, S. J.C. 303,311 292 384,416 Santi,R., see Fassina,G. 605, Sabine,M.S., see Courtice,F.C. Samuelsson, B., see Corey,E.1. 610 54,63 171,192 Sache,E., see Zuber,M. 470, Samuelsson, B., see Green, K. Sarcione, E. J., Bogden, A. E. 522 403,408,417 545,547,566 Sachs,L.,see Pluznik,D.H. 93, Samueisson, B., see Hamberg, M. Sargeant,R., see Baugh,R. 163, 105 141, 146, 154, 157-160, 164, 189 Sadiick,1.R., see Hadden,J.W. 168, 169, 172, 176, 181, 194, Sargent,A. U., Austen,K.F. 319,339 386-388,390-394,402-406, 438,461 Sadowsky,N.L., see Graham, 408,414,418,601,611 J. R. 225,228 Sarkar,N., Fosdick,L.S. 546, Samueisson,B., see Hammar• Safier,L.B., see Marcus,A.J. 566 strom,S. 375, 405, 418 177,197,272,292 Sarkin,E., see Wilkinson,P.C. Safrit,H., Weiss,H.J., Phillips, Samuelsson,B., see Lands, 176,205 G. 171,201 W.E.M. 377, 380,419 Sasazuki, T., see Sato, H. 300, Sagara,A., see Ishioka,T. 550, 'Samueisson,B., see Light,R.J. 312 564 384,419 Satake, K., Rozmanith,J. S., Sagel,J., see Colwell,J. P. 159, Samuelsson,B., see Malmsten, Appert, H., Howard, 1. M. 191 C. 406,419 499,518 Sailer,R., see Urbanitz,D. 467, Samuelsson,B., see Marnett,L.J. Sato,H., Sasazuki, T., Tsuno,H., 520 401,419 Nakajima,H. 300, 312 Sakai,K., Stroud,R.M. 426, Samueisson,B., see Nakano,J. Sato,T., see Suzuki,T. 465,466, 461 412,419 469,519 Salmon,J., see Johnson,R.A. Samuelsson,B., see Needleman, Sato-Omori,T., see Oshima,G. 196 P. 154, 157,199,601,613 471,516 Salvin,S.B., Nishio,J., Gribik, Samueisson,B., see Niehaus, Saul,W., see Maling,H.M. M. 324,341 W.G. 388,420 480,503,515 716 Author Index

Saunders, A. see Ornstein, L. Schild,H.O., Willoughby,D.A. Schorlemmer,H. U., see Burger, 70, 105 331,341 R. 279,289 Saxena, P. N., see Feldberg, W. Schild,H.O., see Ash,A.S.F. Schorlemmer, H. V., see Nichol• 617, 621, 623, 624, 626, 627, 14,19,353,366 son,A. 431,433,458 633, 635, 637, 642, 646, 651, Schild,H.O., see HartIey,R.E. Schotte,C., see Goud,T.J.L.M. 652 571,586 74,103 Scandella,}., Kornberg, A. Schild,H.O., see Willoughby, Schrader,J.W., see Feldman,M. 382,421 D.A. 315,321,342,571,587 76, 102 Scapagnini, U., see Giordano, Schiller, W.R., Suriyapa,C., Schreiber,A.D., Kaplan,A. P., F. 480, 503, 504, 511 Anderson,M.C. 499,518 Austen,K.F. 436, 449, 461 Scarnes, R. c., Harper, M. 1. K. Schiller, W. R., see Anderson, Schreiber,A.D., see Kaplan, 412,421 M. C. 499,506 A.P. 18,22 Scarpa,A., see Scherphof,G.L. Schinders,F., see Rother,K. Schreiber,R.D., Gotze,O., 411,421 443,460 Miiller-Eberhard, H.J. 433, Scarpatia,R., see Colwell,}. P. Schlegel,W., see Paulsrud,J.R. 461 159,191 414,420 Schreiber, R. D., Miiller• Schaberg,A., see Furth,R., van Schlesinger, M., see Rachmile• Eberhard,H.J. 427,461 92,97,102 witz,M. 76,106 Schreiber,R.D., see Medicus, Schachter,M. 16,24,470,518 Schlick,B., see Pirquet,C., von R.G. 458 Schachter,M., see Bhoola,K.D. 231,264 Schreiber, W., see Vinegar,R. 477,506 Schlossman, S. F., Ben -Efraim, 527,567 Schachter,M., see Collier, S., Yaron,A., Sober,H.A. Schreiner, G. E., see Mathew, H.O.J. 499,501,508 238,264 T.H. 188,198 Schreuder,J., see Gool,J., van Schachter, M., see Holdstock, Schlossman, S. E., see Rocklin, 546,548,551,567 D.J. 574,585 R.E. 332,341 Schroder,E. 464, 465, 518 Schaoua,H., see Riihl,H. 119, Schmalzl,F., see Braunsteiner, Schroder,E., Liibke,K. 500, 133 H. 70,100 518 Schapoval,E.E.S., see Garcia, Schmidt,G., see Brade, V. 438, Schubert, M., Hamerman, D. Leme,J. 466, 467, 487, 489, 451 216,230 502, 504, 505, 510, 540, 544, Schmidt,G., see Vogt,W. 429, Schull,W.J., see B1att,LM. 99, 546,550,558,563 447,462 Schayer,R.A. 353,372 Schmidt, S., see Riihl, H. 119, 100 Schulte, T. L., see Huber, W. Schayer, R. W. 572,586 133 Schmitt,F.O., see Hodge,A.G. 549,564 Schayer, R. W., see Moore, T. C. 218,228 SchuItz,D. K., see Grant,J.A. 359,371 Schneeberger, E. E., see Einstein, 348,351,368 Schechter, G. P., see McFarland, L. P. 428,453 SchuItz,E.F., Lapin,D.M., W. 115,132 Schneider, c., see Collier,H. O.J. Lobue,J. 95,106 Scheid,K.F. 645,654 501,508,598,602,609 Schultz,F., see Frey,E. K. 470, Schellen berg, R. R., Adkinson, Schneider, F., J r., see Rosenthale, 510 N.F.,Jr. 347,372 M.E. 605,614 Schultz,F., see Kraut,H. 470, Scherer,}., Janoff,A. 303, 312 Schneider,J.C., see Parkinson, 514 Scherphof, G. L., Scarpa,A., T.M. 408,420 Schultz, H. W. 388,421 Toorenenbergen,A., van Schneider,W.P., see Daniels, Schultz,}., Corlin,R., Oddi,F., 411,421 E.G. 393,416 Kaminker, K., Jones, W. Schiatti,P., see Lerner,L.J. Schoefl,G.L 51,66 296,312 551,565 Schoefl,G.L, see Majno,G. Schultz,}., see John,S. 296, Schiffmann, E., Corcoran, B. A., 36,65,574,581,583,586 310 Wahl,S.A. 121, 122, 134 Schoene,N.W., Iacono,1.M. Schulz,H., Landgrliber,E. 187, Schiffmann, E., Showell, H. V., 178,201 201 Corcoran,B.A., Ward,P.A., Schoener,E. P., Wang,S.c. Schumacher, H. R., Agudelo, Smith, E., Becker, E. L. 120, 621,630,631,654 c.A. 299,312 134 Schofield,J.D., Prockop,D.J. Schur, P. H., see Britton, M. C. Schiffman, E., see Hook, W. A., 218,230 446,451 348,351,369 Schorlemmer,H. U., Allison, Schur,P.H., see Caldwell,J.R. Schiffmann,E., see Showell, A.C. 279,293 438,439,451 H.J. 122,134,137 Schorlemmer,H. U., Davies, P., Schur,P.H., see Hunsicker,L.G. Schild,H.O. 13,24 Allison,A.C. 279, 293 446,447,456 Author Index 717

Schur,P.H., see Komer,D. Sela, M., see Shearer, G. M. Shapiro,S.S., see McKay, 244,263 359,372 D.G. 184,197 Schur, P. H., see Ruddy, S. 446, Sela, M., see Weinstein, Y. 359, Sharp,A.A., see Mitchell, 460 373 J.R.A. 151,198 Schuster,S., see Greaves, M. Selitto,J.J., see Randall,L.O. Sharp,F.R., Hammel,H.T. 476,511 589,597,602,606,614 630,654 Schwab,J. 492, 495, 496, 518 Seljelid,R. 77,106 Sharp,G.C, see Petz,L.D. Schwab,J. H., Cromartie, W. J., Selph,J.L., see Vinegar,R. 528, 446,459 Robertson,B. S. 273,293 530,567 Sharp,G. W.G., see Flores,J. Schwartz,A., Askenase, P. W., Seltzer, H. S., see Blatt,1. M. 305,308 Sharp,J.T., Riggs,S. 256,264 Gershorn,R.K. 365,372 99, 100 Selvaggio,S.S., see Ward,P.A. Shattil,S.J., see Colman,R.W. Schwartz,B., van, see Robertson, 345,348,359,373 168, 172, 191 W. 275,293 Selye,H., Cunnington,J., Shaw, B., see Hebborn, P. 502, Schwartz,H.J., Leon,M.A., Somogyi,A., Cote,G. 529, 512 Pelley,R. P. 326, 341 566 Shaw,F.M., see Curtis,A.S.G. Schwartz,J.C, see Baudry,M. Selye,H., Somogyi,A., Vegh,P. 111,131 354,355,366 555,566 Shaw,J., see Dawson, W. 408, Schwartz,N.L., see Brown,J.H. Semente, G., see Greenbaum, 416 555,556,562 L.M. 309,495,496,511 Shaw,J.E., see Ramwell,P.W. Schwartzman,M., see Raz,A. Semprini, A., see Tallarida, G. 383,421,607,614 394,400,421 590,615 Shazo,CV., de, Henson,P.M., Scott,CG., see Willis,A.L. Senda,N., Tamura,H., Shibata, Cochrane,CG. 444,452 141, 146, 154-159, 164-166, N., Yoshitake,J., Kondo,K., Shazo, C V., de, McGrade, M., 168, 169, 175, 178, 181, 188, Tanaka, K. 113, 124, 134 Henson, P. M., Cochrane, 205,387,422,601,615 Senda,N., see Shibata,N. 269, CG. 452 Scott,D., Jr. 589, 603, 614 293 Shea, S. M. 31, 45, 66 Scott,G.K., see Barkas,T. 426, Senda,N., see Tatsumi,N. 124, Shea, S. M., Caulfield,1. B., 450 134 Burke,J.F. 43,66 Scott,J.G., see Ozge-Anwar, Senior,R.M., Bielefeld,D.R., Shea,S.M., see Majno,G. 36, A.H. 472,516 Jeffrey,J.J. 280,293 66 Scott,J.L., Cartwright,G.E., Senyi,A., see Mustard,J.F. Sheally,C N., see Collins, W. F. Wintrobe,M.M. 165,201 176,199 591,609 Scott,R. B., Robb-Smith,A. H. T. Sergent,J.S., see Frank,M.M. Sheard, P., see Augstein,J. 363, 99, 106 453 366 Scott,S., see Packham,M.A. Setowsky,CA., see Holmsen,H. Shearer, G. M., Melmon, K. L., 151,155,161,200 170,195 Weinstein, Y., Sela, M. 359, Sear,CH.J., Poller,L. 177, Severson,CD., see Thompson, 372 201 J.S. 352,373 Shearer, G. M., Weinstein, Y., Sedgley,M., see Ford,W.L. Sevitt, S. 46, 66, 485, 519 Melmon,K.L. 359,372 112,131 Sevitt,S., Bull,J. P., Cruikshank, Shearer,G. M., see Bourne,H.R. Seeger, R. C, see Oppenheim, CN.D., Jackson,D.M., 345,350,366 J.J. 77,105 Lowbury,E.J.L. 504, 519 Shearer,G.M., see Melmon, Seegmiller,J.E., see Melmon, K.L. 356,358,370 Shafer,A. W., see Karnovsky, K.L. 491,498,499,515,590, Shearer, G. M., see Mozes, E. M.L. 76,104 594,600,613 358,371 Seeler,R., see Booyse,F. 167, Shaff,R.E.,seeKaplan,A. P. Sheffer, A. L., Austen, K. F., 190 352,361,369 Rosen,F.S. 461 Segal,S., Weinstein, Y., Melmon, Sha'hafi,R.L., see Naccache, Sheffer,A. L., Crait,J. M., Wilms• K.L., McDevitt,H.O. 359, H. J. 124, 133 Kretchmer, K., Austen, K. F., 372 Shanahan,R. W. 538,566 Rosen,F.S. 439, 449,461 Segre,D., see Garattini,S. 527, Shanaman,J., see Emele,J.F. Sheffer,A.L., Fearon,D.T., 528,563 602,605,610 Austen,K.F. 461 Seki, T., see Abe, K. 499, 506 Shanberge,J. N., see McKay, Sheffer,A. L., Fearon,D. T., Sela,M., see Matthyssens,G.E. D.G. 184,197 Austen,K.F., Rosen,F.S. 359,370 Shand,F.L., Bell,E.B. 77, 106 461 Sela, M., see Melmon, K. L. Shapanka,R., see Camargo, Sheffer,A. L., see Austen, K. F. 359,370 A. C. M. 473,507 439,450 718 Author Index

Sheffer,AL., see Ruddy,S. Shin, H. S., see Marcus, R. L. Sicuteri,F., Franchi,G., 439,460 432,457 Fanciullacci, M., Del Bianco, Shelton, E., Y onemasu, K., Shin,H.S., see Nicholson,A. P.L. 481,519 Stroud,R.M. 426,461 430, 432, 458 Sicuteri,F., Franchi, P. L., del B., Shemano, I., see Goldstein, S. Shin, H. S., see Snyderman, R. Franciulacci, M. 598, 606, 528, 529, 531, 534, 538-540, 118,134,286,293 614 555,563 Shin,H.S., see Winkelstein,l.A Sicutari, F., Franciulacci, M., Shemano, I., see Hitchens,l T. 444,463 Franchi, G., Del Bianco, P. L. 527, 531, 532, 534, 541, 564 Shin,M.L., see Gelfand,M.e. 592,594,596,614 Sherington, L., see Ziegler, J. B. 447,454 Siegel,A., Liischer,E.F. 272, 430,463 Shio,H., Ramwell,P.W. 156, 293 Sherman,H., Fiasconaro,J.E., 181,201 Siegel,D.e., see Gordon,A.S. Grundfest,H. 601, 602, 614 Shiraishi, S., see N agasa wa, S. 95, 103 Sherrington,e.S. 589,591,614 430,458 Siegert, R., see Phillipp• Sherrington, e. S., see Wood• Shirley,H.H., Jr., see Mayerson, Dormston, W. K. 638, 640, worth,R.S. 589,617 H.S. 33,66 654 Sherry,S.J., see Alkjaersig, N. Shoene,N.W.,Iacono,J.M. Siegmund, E. A., Cadmus, R. A., 449,450 159,170,201 Lu,G. 589, 594, 596, 597, Sheth, U. K., Borison, H. L. Shoji,M., see Meyers,O.L. 602,614 620,655 331,339 Siggins, G., Hoffer,B., Bloom, Shevach,E. M., laffe, E. S., Shore, P.A., Burkhalter, A., F. 607,614 Green,I. 277,293 Cohn, V.A, lr. 352, 372 Sih,e.J., Takeguchi,e.A., Shevach, E. M., see Rosenthal, Shorley, P. G., see Collier, 382, 395, 396, 421 A.S. 76,106 H. O. J. 17,20, 499, 501, 508 Sih,e.J., see Chan,l.A. 390, Shibata, N., Tatsumi, N., Shoshan, S., see Parnham, M. J. 394,395,416 Tanaka, K., Okamura, Y., 554,565 Sih,C.J., see Takeguchi,e. Senda, N. 269,293 Show,E., see Sampaio,C. 470, 395,396,422 Shibata, N., see Senda, N. 113, 518 Sikes,D. 256,264 124,134 Showell, H. J., Becker, E. L. Shibata,N., see Tatsumi,N. Silberman,H.R., see Rosse, 124,134 124,134 W.F. 449,460 Shick,B., see Pirquet,C.V. 12, Showell, E. L., see N accache, Silver, LA. 213,230 23 H.l. 124,133 Silver, M. D., Stehbens, W. E. Shier,K.J., see Dolovich,l. Showell,H.J., see Becker,E.L. 186,201 345,367 119,124,130,271,288 Silver,M.J., Smith,J.B., Shih, T. Y., see Lim, R. K. S. Showell,H.J., Freer,R.J., Ingerman,e. M. 172, 201 589, 594, 613 Zigmond,S.H., Schiffmann, Silver, M. J., Smith, J. B., Inger• Shima, K., see Dannenberg, E., Aswanikumar, S., Corco• man, e., Kocsis,J.l 146, A.M. 87,101 ran, B., Becker,E.L. 122, 153,155,160,201 Shimada, A., see Tamura,N. 134,137 Silver, M.J., Smith,J. B., 434,462 Showell, H. V., see Schiffmann, Webster,G.R. 177, 178,201 Shimamoto, T., see Ishioka, T. E. 120, 134 550,564 Silver, M.J., see Bills, T. K. Shru, K. W., see Robertson, P. B. 159,178,190 Shin,H.S., Mayer,M.M. 428, 280,293 436,448,449,461 Silver,M.J., see Kocsis,ll. Shwartzman,G. 185,201,232, Shin,H.S., Pickering,R.l., 153, 173, 179, 196, 401, 419 236,237,245-247,264 Mayer,M.M. 433, 434,461 Silver,M.l, see Smith,1.B. Shin,H.S., Smith,M.R., Wood, Shyn, K. W., see Robertson, P. B. 154, 157-159, 164, 165, 170, 302,3ff W.B. 436,445,461 173,175-178,202 Shin,H.S., see Brade,V. 431, Sicuteri,F. 17,24,481,500,519, 593,595,596,600,614 Silver,M.J., see Spector,A.A 451 182,202 Shin, H. S., see Cook, e. T. 433, Sicuteri, F., Fanciullacci, M., Silverstein,S.e., see Bianco,e. 452 Franchi,G., Del Bianco, Shin, H. S., see Goldlust, M. B. P. L. 578,586 73,100,442,451 433,434,454 Sicuteri,F., Franchi,G., Bianco, Silverstein, S. C., see Griffin, Shin,H.S., see Kay,A.B. 127, P.L.D., Fanciollacci,M. F. M. 73, 103, 115, 132,442, 132 467,501,519 455 Author Index 719

Silvestrini,B., Burberi,S., Siess, F., see Russell,R.J. 117, Smith,J. B., see Kocsis,l.J. Catanese, B. 548,566 124,126, 128,133 153, 173, 179, 196, 401, 419 Simmons, A, see Thompson, Slichter,S.J., see Harker, L.A. Smith,J.B., see Mills,D.e.8. J.S. 352,363 164,194 150,198 Simmons,H.A, see Horton,J.E. Sloane,E.M., see Erdos,E.G. Smith,J. B., see Silver, M.J. 319,330,339 473,496,509 146, 153, 155, 160, 172, 177, Simmons,S.R., see Karnovsky, Slocumb,C.H., see Hench,P.S. 178,201 M.L. 75,104 550,564 Smith, 1. 8., see Spector,AA Simmons,S., see Karnovsky, Slonecker,e.E., Lim, W.C. 182,202 M.L. 76,104 88, 106 Smith,J. W., Steiner,A.L., Simon,M., see Liideritz,O. Slott, R.I., Zweiman, B. 345, Newberry, W. M., Parker, 618,653 373 e.W. 323,333,341 Simpson,e.W., see Baile,C.A Smaje, L. M., see Verrinder, A. Smith,J. W., Steiner,A.L., 626,627,649 581,587 Parker,e. W. 306, 312, 322, Sinc\air,D.C., Stokes,B.A.R Smart,lV., see Bray,M.A. 341 591,615 320, 325, 327, 332, 333, 337 Smith,J. W., see Parker,e. W. Sinc\air,J.G., Chaplin,M.F. Smerdel,S., see Dekaris,D. 305,311 633,634,655 319,338 Smith,M.E., see Ford,W.L. Sindo,T., see Fujii,G. 449,454 Smiley,J.D., see Ishikawa,H. 112,131 Singclair,M.C., Moore,T.C., 285,291 Smith,M.J.H. 547, 549, 566 Lemmi,e.A.E.,Orlando,J.e. Smith,A.D., Winkler,H. 177, Smith,M.J.H., Colledge,A.J., 359,372 201 Elliott, P. N. e., Bolam,J. P., Singer,S., see Rosenthale, M.E. Smith,A. N., see Feldberg, W. Ford-Hutchinson,A. W. 598,614 578,585 547,566 Singleton,AO. 593,615 Smith, B., see Willis,A.L. 153, Smith,M.1.H., Dawkins,P.D. Singleton,A.O., see Moore, 168, 170, 175, 177, 186,205, 413,421 R.M. 589,593,613 627,631,645,646,655 Smith, M.1. H., Ford-Hutchin• Sinha,J.N., see Bhalla,T.N. Smith, C., Hamerman,D. 299, son,A.W., Elliott,P.N.C., 469,506 312 Bolam,J.P. 547,566 Siraganian,R. P. 352, 372 Smith, E., see Schiffmann,E. Smith,M.l.H., Walker,J.R., 120, 134 Ford-Hutchinson,A. W., Siraganian,R.P., Hook,W.A Smith, F., see Rous, P. 34, 66 Pennington,D.G. 185,202 351,372 Smith,G.M. 152,202 Smith,M.J.H., see Bolam,J.P. Siraganian,R. P., Osler,A.G. Smith,G. M., Egbert,L.D., 488,507,547,561 348,372 Markowitz,R.A., Mosteller, Smith, M. 1. H., see Elliott, Siraganian,R P., Siraganian, F., Beecher,H.K. 596,615 P.N.e. 547,562,563 P.A. 351,372 Smith,J.B. 153, 177,202 Smith,M.J.H., see Ford• Siraganian,R. P., see Hook, Smith, J. B., Ingerman, e., Hutchinson,AW. 175, W.A. 348,351,369 Kocsis,1.J., Silver,M.l 193,547,558,563 Siraganian,R. P., see Ida,S. 154, 159, 164, 170, 173, 177, Smith,M.J.H., see McArthur, 351,369 202 1. N. 547,558,565 Siraganian, P.A., see Sira• Smith,J.8., Ingerman, E. M., Smith,M.R., see Allison,F. ganian,R. P. 351, 372 Silver,M.J. 157, 158, 165, 111, 124, 128, 129 Sissons,J.G. P., see Peters, 175,176,202 Smith, M. R, See Allison, J r., F. D.K. 447,459 Smith,J.B., MacFarlane,D.E. 28,49,62 Sitomer,G., Stroud,R.M., 375,421 Smith,M.R., see Shin,H.S. Mayer,M.M. 428,461 Smith,J.B., Silver,M.J., 436,445,461 Sjoerdsma,A., see Roberts, Ingerman,C., Kocsis,J.J. Smith,M.R, see Winkelstein, W.C. 225,229 175,202 J.A. 444,463 Skaer, R. J., Peters, P. D., Smith,J.B., Silver,M.J., Smith,P.K. 602,615 Emmines,J.P. 141, 201 Webster,G.R. 170,178,202 Smith,P.K., see Davison,e. Skerry,R.J., see Collier,H.O.J. Smith,J. B., Willis, A L. 153, 607,610 609 160, 169, 171, 173, 177, 178, Smith,R., see Roden,L. 215, Skouby,A P. 593, 596,615 202,575,586,606,615 229 Sledge, C., Bing,D.H. 448,461 Smith,J.B., see Bills,T.K. 159, Smith,R.J., Ignarro,L.J. 305, Siess, see Wilkinson, 136 178,190 312 720 Author Index

Smith,R.T., Bauscher,J.A.C., Solomon, L. M., Juhlin, L., Spangler,A.S., Antoniades, Adler, W. H. 322, 330, 341 Kirschbaum,M.B. 598, H.N., Sotman,S.L. 551,566 Smith,T. 12,24 615 Spanoudis,S., Eichbaum,F., Smith, W.L., Lands, W.E.M. Solotorovsky, M., Tewari, R. P. Rosenfeld,G. 236,264 401,402,421 76, 106 Sparrow,E. M., Wilhelm,D. L. Smyth,D.C., see Elliot,D.F. Solum,N.O. 145,202 477,478,505,519 464,509 Somers,K., see Collier,J.G. Sparrow,E.M., see Wilhelm, Snell,E.S. 619,647,655 598,609 D.L. 478,522 Snider, D. E., see Parker, C. W. Sommer,G., see Katz,S.!. Sparshott,S.M., see Ford,W.L. 322,340 249,263 112,131 Snyder,D.S., see Hsia,S.L. Somogyi,A., see Selye,H. 529, Spaulding,W.B. 449,461 606,612 555,566 Speck,L., see Thueson,D.O. Snyder,S.H., Baldessarini,R.J., Sonak,R., see Fischer,H. 111, 351,373 Axelrod,J. 352,373 131 Spector,A.A., Hoak,J.C., Snyderman, R., Altman, L. C., Sl

Spieler,P.T., see Weissmann, Sproull, M., see McIntire, F. C. Stecher, V.J., Sorkin, E., G. 268, 270, 294 15,22 Ryan,G.B. 120,134,176, Spielvogel,A.R. 185,202 Spudich,J.A., Lin,S. 269, 202 Spilberg, I., Osterland, C. K. 293 Stecher, V.J., see Wissler,J.H. 490,519 Spuddich,J.A., see Lin,S. 269, 118,136 Spilberg,l., see Weissmann,G. 292 Stecher-Levin, V.J., see Rother, 299,313 Spurlock,S.E., see Bing,D.H. U. 434,460 Spink, W., see Melby,J. 550, 427,451 Stecher-Levin, V.J., see Wilkin• 565 Srurges,E.A., see Ford-Hut• son,P.C. 176,205 Spires, V.M.C., see Curtis, chinson,A. W. 547, 558, 563 Stechschulte,D.J. 352, 362, AS.G. 111,131 Stahlman,M.T., see Friedman, 373 Spiro, D., see Giacomelli,!. Z. 159, 193 Stechschulte,D.J., Austen,K.F. 36,64 Stanford, D., see Roth,G.J. 182,202 Spiro, D., see Wiener,J. 51,67 179,201 Stechschulte,D.J., Orange,R. P., Spitler,1., Benjamini,E., Stanford,N., see Roth,G.J. Austen,K.F. 362, 373 Young,J.D., Kaplan,H., 383,421 Stechschulte,D.J., see Kay, A. B. Fudenberg, H. H. 332, Stanley,E.R., Hansen,G., 127,132 341 Woodcock,J., Metcalf,D. Stechschulte,D.J., see Orange, Spitzer,R.E., Vallota,E.H., 95, 107 R.P. 371 Forristal,J., Sudora,E., Starbuck,W.C., see Delmonte, Steele,R.H., Wilhelm,D.1. Stitzel, A., Davis,N.C., West, 1. 95,101 29,66 C.D. 430,447,462 Starkey, P.M., see Barrett,A.J. Stefanovic,J., see Ferencik,M. Spitzer,R.E., see Vallota,E.H. 300,307 300,308 447,462 Starling,E.H. 33,66 Steggemann,1., see Gemsa,D. Spitznagel,J.K., Chi,H.Y. Starr, I., Jr., see Gammon,G.D. 305,308 112,134 531,563 Stehbens,W.E., see Silver,M.D. Spitznagel,J.K., Daldorf,F.G., Starr, M.S., West,G.B. 484, 186,201 LetTell, M.S., Folds,J.D. 494,495,503,519 Stein, A., see Powers,S.R. 499, 296,312 516 Spitznagel,J.K., Dalldorf,F.G., Starr, M.S., see Ankier,S.1. LetTell,M.S., Folds,J .D., 467,506 Steinberg,P., Ishizaka,K., Welsh,I.R.H., Cooney,M.H., Starr,M.S., see Dawson,W. Norman,P.S. 360,373 Martin,1.E. 268,293 494,495,503,508 Steiner,A.1., see Smith,J. W. Spitznagel,J.K., see Folds,J .D. Starzecki,B., see Margolis,J. 306, 312, 322, 323, 333, 341 268,290 467,515 Steiner,M. 139,202,422 Spitznagel,J.K., see Golub,E.S. Stastny,P., Cooke,T.D., ZifT,M. Steinetz,B.G., see Di Pasquale, 302,309 255,264 G. 531,537,538,562 Spitznagel,J. K., see Herion,J .C. Stastny, P., Stembridge, V. A., Steinman,R. M., Cohn,Z. A. 303,309 Vischer, T., ZifT, M. 224, 230 72,74,76,107,277,293 Spitznagel,J.K., see Lefell,M.S. Stastny,P., ZifT,M. 256,264 Stekelman,R., see Pounder, 296,311 Stastny,P., see Andreis,M. R. E. 355,371 SpitznageJ,J.K., see Welsh, 259,260 Stelle,R., see Chang,J. 286, I.R.H. 296,313 Staszewska-Barczak,J., 289 Spitznagel,J.K., see Zeya,H.1. Ferreira,S. H., Vane,J.R. Stelwagen, P., see Hamberg, U. 184,205,303,313 600,615 467,512 Spooner,B.G., see Wessels, Staub,A. M. 14,24 N.K. 269,294 Stembridge, V.A., see Stastny, P. Staub,AM., see Bovet,D. 14, Spooner,B.S., see Wessells, 224,230 20 N.K. 140,204 Stephenson,J.D., see Artunkal, Staub,A.M., see Ltideritz,O. Spragg,J. 345,373 A.A 621,629,631,632,647, 653 Spragg,J., Austen,K.F. 467, 649 Stawiski, M., see Hammarstrom, 519 Stern,J.A., see Brown,M.1. Sprecher, H., Lee,C.J. 380, S. 375,405,418 534,562 421 Stecher,V.J. 76,107 Stetson,C.A. 299,312,443, Springer, A., see Kletzien,R.F. Stecher, V.J., Sorkin,E. 234, 462 269,291 264 Stetson, C. A., Jr. 245,264 722 Author Index

Stetson,e.A., Jr., Good,R.A. Stoughton, R. B., see Wuepper, Sturmer, E., see Boissonnas, 246,264 K.D. 234,265 R.A. 16,20 Stetson, C., J L, see Thomas, L. Stovin, P., see Ding1e,J. T. 283, StUrmer,E., see Konzett,H. 236,265 290,300,308 477,499,513 Stevenson,D.D., see McDo• Strand,J.e., see McGiff,J. e. StUrmer,E., see Pless,J. 464, nald,J.R. 351,370 408,419 516 Stewart,J.M., Woolley,D.W. Strandberg,K., Hamberg,M. Sturgess,R., see Parratt,J.R. 500,519 404,422,601,611 185,200,412,420 Stewart,J. M., see Greene,L.J. Strannegard, I. -L., S trannegard, Sturner,E., see Boissonas,R.A. 488,511 b. 358,365,373 474,507 Stewart,J. M., see Ryan,J. W. Strannegard, b., see Stranne• Subramanian,G., see 473,518 gard,I.-L. 358,365,373 Northover, B.J. 185, 199, Stewart,J. W., see Armstrong,D. Straugham, D. W., see Harvey, 501,502,516 16,19,480,484,493,498,502, e.A. 638,652 Suby,H.I., see Graham,J.R. 506,591,593,608 Streeten, D. H. P., Kerr, e. B., 225,228 Stewart,1. W., see Jepson,J. B. Kerr, L. P., Prior, J. e., Sudora,E., see Spitzer,R.E. 16,22 Dalakos, T. G. 500, 519 430,447,462 Stitt,J. T. 624,628,630,655 Streseman.E., see Herxheimer, Suhaciu, G., see Cirstea, M. Stitt,lT., Hardy,J.D. 625, H. 499,512 467,495,507 629,630,655 Strobach,H., see Greeff,K. Sullivan, T. J., Parker, K. L., Stitt,J.T., Hardy,J.D., Stolwijk, 467,469,499,511 Eisen, S. A., Parker, e. W. A.J. 628,630,655 Strom, T. B., Deisseroth,A., 349,373 Stitt,l. T., see Crawshaw, L.I. Morganroth,J., Carpenter, Sullivan, T. J., see Parker, e. W. 625,629,651 C.B., Merrill,J.B. 306, 312 322,340 Stitzel, A., see Spitzer,R. E. Strong,e.G., Bohr,D.F. 604, Sun,D. D. 408 430,447,462 605,615 Sun,F.F., Armour,S.R. 409 Stokes, B. A. R., see Sinclair, Stroud,R.M., Austen,K.F., 422 D.e. 591,615 Mayer, M. M. 428, 448, 462 Sun,F.F., see Johnson,R.A. Stroud,R. M., Nagaki,K., Stoklaska,E., see Rudas,B. 196 Pickering,R.J., Gewurz,H., 528,529,531,533,566 Suolanen,R., see Toivanen, P. Good,R.H., Cooper,M.D. Stolfi,R. 435,448,462 551,566 Stolwijk,A.J., see Stitt,J.T. 427,462 Suriyapa,e., see Schiller, W.R. Stroud,R. M., see Hurst, M. M. 628,630,655 499,518 426,456 Stolwijk,J.A.J., see Cabanac, Sutcliffe,M.e., see Bryant,R.E. Stroud, R. M., see Loos, M. M. 630,650 111,130 Stolwijk,J.A.J., see Hardy,J.D. 449,457 Sutherland, E. W., see Broadus, Stroud,R. M., see Nagasawa,S. 591,611 A. E. 305, 308 Stone,K.J., see Willis,A.L. 430,458 Suttie,l W., Jackson,e. M. 157,172,178,205 Stroud,R. M., see Pickering, Stoner,J., Manganiello, V.C., R. J. 426,459 163,202 Sutton,J.S., Weiss,L. 69, 107 Vaughan,M. 346,373 Stroud,R. M., see Sakai, K. Storm,E., see Holmsen,H. 426,461 Suwanwela,N., see Kwaan, 141, 160, 164,195 Stroud,R. M., see Shelton,E. A.C. 159,196 Stormoken,H.,Owren,P.A. 426,461 Suzuki,K., Suzuki,K. 98, 107 162,202 Stroud,R. M., see Sitomer,G. Suzuki, K., see Suzuki, K. 98, Stormorken, H., see Day, H. 1. 428,461 107 176,192 Stroud,R.M., see Yonemasu,K. Suzuki,M., see Fujii,G. 449, Stormorken,H., see Holmsen, 426,463 454 H. 141, 146, 160, 164, 195 Strunk,R., Colten,H.R. 428, Suzuki,T., Iwanaga,S., Sato,T., Stossel, T. P., Hartwig,J.H. 462 Nagasawa,S., Kato, H., 124, 125, 134 Strunk, R. S., Tashjian, A. H., Yano,M., Horiuchi,H. 465, Stossel, T., Pollard, T. D. 124, Colten,H.R. 428,433,462 466,469,519 134,269,293 Stuart,A.E. 68,107 Suzuki, T., Nagasawa, M. Y., Stossel,T.P., see Hartwig,J.H. Sturmer,E. 486,519 Takahashi,H., Kato,H. 124,132 Sturmer,E., Berde,B. 464,519 176,202 Stossel, T. P., see Mangianello, Sturmer, E., Cerietti,A. 477, Suzuki,T., see Komiya,M. V. 305,311 480,519 466,513 Author Index 723

Suzuki,T., see Oshima,G. 471, Taichman,N.S., see Movat, Tangri,K.K., see Bhalla,T.N. 516 H.Z. 183,198 469,506 Suzuki,T., see Yano,M. 466, Tainer,J.A., Turner,S.R., Tappel,A.L. 302,312,402, 469,522 Lynn, W. S. 120, 134 404,422 Svanborg,K., see Portoghese, Tainer,J.A., see Turner,S.R. Tappel,A.L., see Hutton,J.J., P. S. 401,42 I 120,135,375,376,422 Jr. 220,228 Svejcar,J., Johanovsky,J., Tainer,S.A., see Turner,S.R. Tashjian,A.H., see Rommel, Pekarek,]. 315,341 176,203 F.A. 434,460 Svejcar,J., see Krejci,J. Taira,N., see Hashimoto,K. Tashjian,A.H., see Strunk,R.S. 331,339 594,611 428,433,462 Svensson,J., Hamberg,M., Takahashi, H., see Suzuki, T. Tashjian,A.H.J., Voelkel,E.F., Samuelsson,B. 157,202, 176,202 McDonough,]., Levine,L. 601,615 Takeguchi,e., Kohno.E., 178,202 Svensson,]., see Hamberg,M. Sih,C.J. 395,396,422 Tatsumi,N., Shibata,N., 146, 154, 156-160, 164, 168, Takeguchi,C., Sih,e.J. 396, Okamura, Y., Takeuchi, K., 169, 172, 181, 194, 386-388, 422 Senda,N. 124,134 390-392,404,418,601,611 Takeguchi,C., see Chan,J.A. Tatsumi,N., see Shibata,N. Svensson,J., see Malmsten,e. 390,394,395,416 269,293 146, 157, 166, 168, 171, 172, Takeguchi, C. A., see Sih, C. J. Tattersall, M. L., see Augstein, 197,406,419 382,395,396,421 J. 363,366 Svensson,J., see Nishizawa, Takeuchi,K., see Tatsumi,N. Tauben,D., see DeBernardo, R. M. 359,367 E.E. 157,175,199 124,134 Swangler, M., see Alexander, B. Takeuchi,T., see Umezawa,H. Taubman, S. B., Goldschmidt, P.R., Lepow,I.H. 301, 312 163,189 300,312 Sweatman, W.J.F., see Collier, Takeuchi, Y., see Movat, H.Z. Taylor,E.L., see Wessells,N.K. H.O.J. 606,609 302,311 140,204,269,294 Sweatman,W.J.F., see Dawson, Talamo,R.e., see Bagdasarian, Taylor, E. W., see Weisenberg, W. 410,416 R.A. 472,506 R.C. 303,304,312 Sweetman,B.J., see Oelz,O. Taylor,R.E., see Robertson, Talamo,R.e., see Lahiri,B. 173,200 P.B. 280,293,302,311 469,470,514 Sweetman, F., see Ornstein, L. Taylor,S.M., see Kerby,G.P. 70,105 Talamo,R.e., see Newball, 299,310 Swenson,C.B., see Neher,G.M. H.H. 345,348,351,371 Temple,A., Loewi,G., Davies, 256,263 Talamonti,R. 1,4 P., Howard,A. 270,293 Swieton, Baron G. von 1,4 Talbot,e.H., see Trapnell,J.E. Ten Bensel,R., see Kohler,P.F. Swingle,K.F. 588,615 500,520 446,456 Swinson,D.R., Bennet,A., Tallarida,G., Cassone,R., Terada, H., Baldini,M., Hamilton,E.B.D. 179, Semprini,A., Condorelli, Ebbe,S., Madolf,M.A. 186, 202 590,615 203 Switzer,W.P., see Roberts,E.D. Tampion,W., see Ahkong,Q.F. Ter Laan,B., Molenaar,J.L., 256,264 115,129 Feltkamp-Vroom, T. M., Szabo, E., see Goldstone,A. Tamura,H., see Senda,N. 113, Pondman, K. W. 440, 462 297,309 124,134 Terragno,A. M., see McGilf, Szczeklik,A., see Gryglewski, Tamura,N., Nelson,R.A. 430, J.e., 488, 514 R.J. 168,172,194 462 Terragno,N.A., see McGilf,J.C. Szentgyorgyi,A. 525 Tamura,N., Shimada,A. 434, 408,419,606,613 Szidon,J.P., see Pietra,G.G. 462 Tevethia,S.S., Zarling,J.M., 38,66 Tamura,N., see Nelson,R.A. Flax, M. H. 77, 107 Szolcsanyi,]., see Jancs6, N. 433,438,458 Tewari, R. P., see Solotorovsky, 487,513,557,564 Tan,L., Wang,H.M., Lehoux, M. 76,106 Szolcsanyi,]., see Jancso• J.-G. 402,422 Thal,A. P., Kobold,E.E., Gabor,A. 557,564 Tanaka,K., see Senda,N. 113. Holenberg,M.l. 499, 519 124,134 Theobald,M., see Domenjoz,R. Tai,H.H., see Zurier,R.B. Tanaka,K., see Shibata,N. 528,562 303-305,313,356,357,373 269,293 Theofilopoulos,A. N., Perrin, Taichmann, N.S., Uriuhara, T., Tangri, K. K., Bhargava, A. K., L.H. 441,462 Movat,H.Z. 186,202 Bhargava,K. P. 621,655 Thoma,R. 7,24,212,230 724 Author Index

Thomas,G., West,G.B. 489, Till,G., see Gemsa,D. 305, Trinkaus,J.P. 109,134 520 308 Tripp,L., see Di Pasquale,G. Thomas,J., see Partridge,S.M. Tilney,L.G., see Marsland,D. 553,562 222,229 304,311 Trnka,Z., Hay,J.B., Lachmann, Thomas,L. 246, 265, 299, 312 Timsit,J., see Giroud,J.P. 259, P. J. 239,265 Thomas,L., Stetson,C., Jr. 262,536,563 Troll,W., see Zweifach,B.W. 236,265 Timsit,J., see Velo,G.P. 257, 502,522 Thomas,L., see David,J.R. 265 Troquet,J., see Lecomte,J. 315,338 Tislow,R., see La Belle,A. 597, 499,501,514 Thomas,L., see Good,R.A., 612 Trost,R., see Ginsburg,1. 255, 185,.193,246,262 Todd,E., see Piliemer,L. 235, 261 Thomas,L., see Weissmann,G. 264 Truax,J.F., see Vinegar,R. 482,521 Todd,E.W., see Pensky,J. 459 528-530,567 Thomas,L.L., Bochner,B.S., Todd,E.W., see Piliemer,L. Tsagaris, T.G., see Anderson, Lichtenstein, L. M. 365, 428,432,459 F.L. 412,415 373 Todd,J., see Gordon,S. 282, Tsan,M.F., Berlin,R.D. 115, Thomas, L. L., Lichtenstein, 290 134 L. M. 351,373 Toivanen,P., Maatta,K., Ts'ao,C.H. 142,203 Thomas,R.H., see Arman,C.G. Suolanen,R., Tykkylainen,R. Tschopp,T.B. 144, 151,203 van 490,504,520 551,566 Tschopp,T.B., Baumgartner, Thomas, W., see Braunstein,H. Tomioka,H., see Ishizaka, T. H.R. 151,203 99,100 347,369 Tschopp,T.B., Weiss,H.J. Thomas Blake,J., see Rosenthal, Tomita,K., see Ichikawa,A. 165, 169,203 A.S. 77,106 554,564 Tschopp,T.B., Weiss,H.J., Thompson, A. G., see Popierai• Tomita,K., see Yoshimoto,A. Baumgartner,H.R. 166, tis,A.G. 499,516 395-397,422 203 Thompson,A.G., see Ryan, Tomkins,G.M., see Kram,R. Tschopp,T.B., Zucker,M.B. J. W. 467,499,518 306,310 169,203 Thompson, E. B., see Levisohn, Tomlinson,R.V., Ringold,H.J., Tschopp,T.B., see Baum• S.R. 428,457 Qureshi, M. C., Forchielli, E. gartner,H.R. 143, 190 Thompson,J., Furth,R. van 203,396,422 Tschopp,T.B., see Weiss,H.J. 79,88-90,107 Tompkins,E.H. 88,107 165,166,169,204 Thompson,J.S., Severson,C.D., Tonietti,G., see Dixon,F.J. Tse,R.L., Phelps,P., Urban,D. Parmely, M.J., Marmorstein, 243,261 125,135 B.L., Simmons,A. 352, 373 Toorenenbergen,A. van, see Tsuda,T., see Dannenberg, Thompson, P.L. 49,67 Scherphof,G.L. 411,421 A.M. 87,101 Thompson,P.L., Papa• Toppozada,M., see Green,K. Tsung, P.-K., Hermina, M., dimitriou,J.M., Waiters, 402,417 Weissmann,G. 306,312 M.N.1. 112,134 Torioni,H., see Enzinger,F.M. Tsuno,H., see Sato,H. 300, Thompson,R.A. 430,462 224,228 312 Thompson,R.A., Lachman, Toullet,F., see Voisin,G.A. Tucker m,E.S., see Wuepper, P.J. 434,462 326,341 K.D. 522 Thompson,R.A., see Lach• Townsend,D., see Gerrard,J.M. Turitto, U. T., see Baumgartner, mann,P.J. 235,263, 434, 193 H.R. 143,190 457 Toyoda,T., see Inoki,R. 491, Turk,J.L. 247, 265, 314, 341 Thorbecke,G.J., see Rother, U. 513 Turk,J.L., Parker,D. 249,265 434,460 Turk,J.L., Parker,D., Thorogood,P., see Moncada,S. Trainier, Y., see Vargaftig,B.B. Pouiter,L.W. 249,265 198 156,203 Thorp,G.A., see Miert,A.S. van Tranzer,J. P., see Pletscher,A. Turk,J.L., Pouiter,L. W. 249, 640,655 141,200 265 Thorpe,W.V., see Best,C.H. Trapnell,J.E., Righby,C.C., Turk,J.L., see Katz,S.1. 239, 13,19 Talbot,C.H., Duncan,H.L. 249,250,263,359,369 Thrasher, S. G., Yoshida, T., 500,520 Turk,J.L., see Lewis,E. 241, Oss,C.J. van, Cohen,S., Traub,W., Piez,K.A. 217, 246,263 Rose,N.R. 121,134 230 Turk,J.L., see Maillard,J.L. Thueson,D.O., Speck,L., Trautschold,l., see Werie,E. 239,263 Grant,J.A. 351, 373 465,469,521 Turk,J.L., see Nath,I. 252,263 Author Index 725

Turk,J.L., see Pick,E. 239, Unkeless,J.C., Gordon,S., Vane,J.R. 17,24,175,181,203, 264,317,326,340 Reich,E. 281,293 334, 341, 375, 412, 422, 488, Turk,J.L., see Polak,L. 236, Unkeless,J.e., see Gordon,S. 520, 572, 575, 586, 587, 604, 246,250,264 274,281,290 615,617,631,637,655 Turk,J.L., see Wemambu, Urban,C.L., see Jamieson,G.A. Vane,J.R., see Bennett,A. 393, S.N.C. 242,265 110,132 416 Turk,J.L., see Whittle,H.e. Urban,D., see Tse,R.L. 125, Vane,J.R., see Blackwell,G.J. 244,265 135 159, 178, 190, 396, 397, 400, Turk,J.L., Willoughby,D.A. Urbanitz,D., Sailer,R., 409,411,416 231,265,536,567 Habermann,E. 467,520 Vane,J.R., see Bunting,S. 155, Turk,V., see Lebez,D. 300, Urihara,T.S., see Burke,J.S. 191, 601,609 311 270,289 Vane,J.R., see Ferreira,S.A. Turker,R.K., see Khairallah, Uriuhara,T., see Movat,H.Z. 375, 406, 408, 417, 472, 473, P.A. 604,605,612 183,198 488, 501, 503, 509, 510, 527, Turner,S.R., Campbell,J.A., Uriuhara,T., see Taichmann, 563, 575, 576, 585, 589, 590, Lynn, W.S. 120,135 N.S. 186,202 592, 594-600, 602, 604-608, Turner,S.R., Tainer,J.A., 610 Lynn, W.S. 120, 135, 176, Vaes,G., Eechout, Y. 301,312 Vane,J.R., see Ferreira,S.H. 203,375,376,422 Vagg, W.J., see Baumgarten, 17,28, 178, 193 Turner,S.R., see Tainer,J.A. A. 477,506 Vane,J.R., see Flower,R.J. Vail,M.S., see Robertson,P.B. 120, 134 153, 193, 400, 417, 607, 610, Tweed,M.F., see Jasani,M.K. 280,293 645,646,652 259,262 Vainer,H. 138.139,203 Tykkylainen,R., see Toivanen, Vairel,E., see Hureau,J. 499, Vane,J.R., see Gilmore,N. P. 551,566 513 152,193 Valentine, F. T., Lawrence,H.S. Vane,J.R., see Gryglewski,R. Ubatuba,F.B., Harvey,E.A., 321,341 142, 157, 158, 175, 194, 392, Ferreira,S.H. 181-183, 203 Valentine,L., see Praga,e. 417,601,611 Udenfriend,S., Waalkes,T.P. 164,200 Vane,J.R., see Johnson,R.A. 15,24,183,204 Valentine,M.D., see Orange, 196 Udenfriend,S., see Hutton,J.J, R. P. 362,371 Vane,J.R., see Moncada,S. Jr. 220,228 Vallota,E.H., Forristal,J., 154, 173, 198, 488, 515, 588- Ukena, T.E., Berlin,R.D. 115, Spitzer,R.E., Davis,N.C., 590, 592, 594, 595, 597, 600, 135, 140,203 West,C.D. 447,462 601,604,606,613 Ukena,T.E., see Berlin,R.D. Vallota, E. H., Gotze, 0., Spiegel• Vane,J.R., see Needleman,P. 115,130 berg,H.L., Forrestal,J., West, 154,157,199,601,613 Ulett,G.A., see Brown,M.L. e.D., Miiller-Eberhard,H.J. Vane,J.R., see Nijkamp,F.P. 534,526 430,462 412,420 Ullman,H.L., see Marcus,A.J. Vallota,E.H., Miiller-Eberhard, Vane,J.R., see Palmer,M.A. 272,292 . H.J. 301,312,345,373,436, 380,420 Ullman,M.L., see Marcus,A.J. 462 Vane,J.R., see Piper,P.J. 157, 177,197 Vallota,E.H., see Spitzer,R.E. 181, 200, 377, 390, 392, 409, Ullyot,J.L., see Bainton,D.F. 430,447,462 421, 488, 516, 555, 566, 597, 297,307 Valone,F.H., Austen,K.F., 598, 601, 606, 614, 631, 654 Umezawa,H., Aoyagi,T., Goetzl,E.J. 173,176,203 Morishima,H., Matsuzaki, Valone,F.H., see Lewis,R.A. Vane,J.R., see Staszewska• M., Hamada,M., Takeuchi, 348,350,370 Barczak,1. 600, 615 T. 300,312 Van den Berg,G.J., see Kerck• Varagic, V.M., Beleslin,D.B. Umezu,K., see Ichikawa,A. haert,J.A.M. 250,263 636,643,655 554,564 Vanderhoek,J. Y., see Lands, Vargaftig,B.B., see Bonta,l.L. Unanue,E.R. 76,107 W.E.M. 400,419 551,562 Unanue,E.R., see Cochrane, Van der Wende,C., Margolin, Vargaftig, B. B., Chingard, M. e.G. 271,289,299,308 S. 597,615 155,156,203 Ungar,G., Damgaard,E., Vane,F.M., see Willis,A.L. Vargaftig,B.B., Dao Hai,N. Hummel,F.P. 502,520 141, 146, 154-159, 164-166, 380,411,422 Unger,W.G., see Eakins,K.E. 168, 169, 175, 178, 181, 188, Vargaftig,B.B., Trainier, Y., 175,192 205,387,422,601,615 Chignard,M. 156,203 726 Author Index

Vargaftig, B. B., Zirnis, P. 146, Vincent,J.E., Bonta,I.L., Vries• Voison,G.A., see Fallah,H.A. 153,157,203 Kragt,K., de, Bhargava,N. 358,368 Vargaftig,B.B., seeChignard,M. 551,567 Voisin,G.A., see Mai\lard,J.L. 154, 155, 191 Vincent,J.E., Melai,A., Bonta, 241,263 Vargaftig,B.B., see Lefort,J. I. L. 168, 172,203 Volanakis,J.E., see Hurst,M.M. 181, 182, 197 Vincent,J.E., Zijlstra,F.J., 426,456 Varley,H. 403,422 Bonta,l.L. 159,203 Volanakis,J.E., see Loos,M. Varsa,E.E., see Handler,E.S. Vincent,J.E., see Bonta,l.L. 449,457 95, 103 543,554,561,562 Volkman,A. 107 Vaughan,J.H., see George,M. Vinegar,R., Macklin.A.W., Volkman, A., Collins,F.M. 86, 315,317,338 Truax,J. F., Selph,J.L. 528, 107 Vaughan,M., see Mangianello, 530,567 Volta, F., see Coceani,F. 393, V. 305,311 Vinegar, R., Schreiber, W., Hugo, 416 Vaughan,M., see Stoner,J. R. 527,567 Vonkeman,H., Dorp,D.A., van 346,373 Vinegar,R., Truax,J.F. 529, 377,380,422 Veale, W.L., Cooper,K.E. 567 Vonkeman,H., see Dorp,D.A., 620-622, 624, 629, 633, 634, Virchow,R. 3,4,7, 10, 11, 18, van 384,417 Voorhees,J.J., see Hammar• 637,646,647,655 24 Veale, W.L., see Cooper,K.E. Virolainen,M. 77,107 strom,S. 375,405,418 Vreeken,J., see Aken, W.G., van 622,633,634,646,650 Vischer,T., see Stastny,P. 224, 187,203 Veale,W.L., see Feldberg,W. 230 Vries, A., de, see Jerushalmy,Z. 622,642,643,651,652 Vishwanathan,C.T., Rudy,T.A. 187,196 Veale, W.L., see Pittman,Q.L. 634,655 Vries-Kragt,K., de, see Vincent, 621,626,647,654 Viswanathan,C.T., see Rudy, J. E. 551,567 Veale,W.L., Whishaw,1. 627, T.A. 626,634,654 Vugman,1. 469,520 Vliet,L., van, see Bonta,l.L. 655 Vugman,l., Rocha e Silva,M. Vegh,P., see Kovats,T.G. 245, 554,562 573,587 263 Voelkel,E.F., see Tashjian, Vugman, T. 14,25 Vegh, P., see Selye,H. 555,565 A.H.J. 178,202 Veis,A., see Brownwell,A.G. Vogel,R., Werle,E. 469, 470, Waaler,B.A. 499,520 A.G. 220,227 520 Waaler,B.A., see Jacobsen,S. Veis,A. see Clark,C.C. 221, Vogel, R., see Werle,E. 470,521 487,513 227 Vogin,E.E.,seeHuber, W. 549, Waalkes,T.P., Weissbach,H., Velo,G.P., Dunn,C.J., Giroud, 564 Bozicevich, J., U denfriend, S. J. P., Timist,J., Willoughby, Vogt, W. 465,466,520 183,204 D.A. 257,265 Vogt, W., Dames, W., Schmidt, Waalkes, T. P., see U denfriend, S. Velo,G.P., Spector,W.G. 212, G., Dieminger,L. 429, 462 15,24 230 Vogt, W., Dieminger, L., Lynen, Waarde,D., van 96, t07 Velo,G. P., see Giroud,J. P. R., Schmidt,G. 429, 462 Waarde,D., van, Hulsing• 260,262 Vogt,W., Meyer,U., Kunze, H., Hesselink,E., Furth,R., van Verhaegen, H., DeCock, W., LulTt,E., Babilli.S. 380, 422 84, 93, 94, 96, 107 DeCree,J. 358, 365, 373 Vogt, W., Schmidt, G., Lynen, R., Waddell, A. W., Robson,R. T., Vermylen,J., see Donati,M.B. Dieminger,L. 447,462 Edwards,J.G. 111, 135 162,192 Vogt,W., Zeman,N., Garbe,G. Wagner,K., see Glatt,M. 76, Vernon-Roberts,B. 68, 107 440,462 103 Vernon-Roberts, B., Jessop, Vogt, W., see Bartels,J. 380, Wagner,M.,see Huber,H. 277, J.D., Dore,J. 259,265 415 291 Verrinder,A., Fraser,P., Smaje, Vogt,W., see Brade,V. 438, Wagner, W. H., Hahn, H., Evans, L. M. 581,587 451 R. 68,107 Verveen,A.A. 95,107 Vogt, W., see Kunze,H. 377, Wagner-J auregg, T., see Biich, Veselic,B., see Dekaris,D. 319, 411,419 O. 528, 529, 535, 562 338 Vogt,W., see Riihl,H. 119,133 Wahl,L.M., Wahl,S.M., Vick,J.A., see Hinshaw,L.B. Vogt, W., see Windaus,A. Mergenhagen, S. E., Martin, 184,195 13,25 G.R. 280,287,293 Vi\lablanca,J., Myers,R. D. Voisin,G.A., Toullet,F. 326, Wahl,S.A., see Corcoran,B.A. 620,655 341 121,122,134 Author Index 727

Wahl,S.M., Altman,L.C., Ward,P.A. 18,25,55,67, 125, Watanabe,N., see Abe,K. 499, Rosenstreich,D.L. 333,341 126, 135, 234, 265, 303,312, 506 Wahl,S.M., Iverson,G.M., 435,440,463,482,520,567 Waters,M.F.R., see Wemambu, Oppenheim,J.J. 119, 135 Ward,P.A., Becker,E.L. 124, S.N.C. 242,265 Wahl,S.M., see Hook,W.A. 135 Watson,D., see Galanos,C. 348,351,369 Ward,P.A., Cochrane,C.G. 618,652 Wahl,S. M., see Koopman, W.J. 235,241,265 Watson,L., see Alper,C.A. 442,456 Ward, P.A., Cochrance;C.G., 429,450 Wahl,S.M., see Wahl,L.M. Miiller-Eberhardt,H.J. 233, Wattiaux,R., see De Duve,C. 280,287,293 234,265 482,508 Wakabayashi,T., see Hamberg, Ward, P .A., Cohen,S., Flanagan, Waud,R.A., see Deneau,G.A. M. 154, 156, 158, 160, 164, T .D. 119,135 596,601,605,601 168, 181, 194,386,387,418 Ward,P.A., Dvorak,H.F., Waugh,D.F., see Noble,R.W. Walaszek, E. J., see Garcia Leme, Cohen,S., Yoshida, T., Data, 120,133 J. 480,501,510 R., Selvaggio,S.S. 345,348, Wawretscheck, W.A., see Lewis, Walker,J.R., see Ford• 359,373 G.P. 487,514 Hutchinson,A. W. 175, 193, Ward, P.A., Hill,J.C. 301, 312 Wax,J., see Winder,C.V. 531, 547,563 Ward,P.A., Hill,J.H. 234, 567, 582, 587 Walker,J.R., see Smith,M.J.H. 265,286,293 Waxman,B.H., see Ruddle,N. 185,202 Ward,P.A., Lepow,I.H., H. 279,293 Waiker,R.I., see Herion,J.C. Newman, L. J. 120,135 Webb,J., see Rooney,P.J. 544, 303,309 Ward,P.A., Remold,H.G., 566 Walker,R.I., see Herring, W.B. David,J.R. 118,135,319, Webster,G.R., see Silver,M.J. 185,195 328, 332, 341 177, 178,201 Wallach,D.P. 384,422 Ward, P .A., Zvaifler, N.J. 301, Webster,G.R., see Smith,J.B. Wallach,D.P., Daniels,E.G. 312,446,463 170,178,202 396,397,422 Ward,P.A., see Cohen,S. 319, Webster,M.,seePisano,J. 18, Waller,A.V. 3,9,10,25 337 23 Waller,M.B., Myers,R.D. Ward,P.A., see Lepow,I.H. Webster,M.E. 464,470,471, 625,655 18,22 520 Walsh,P.N. 162,204 Ward, P.A., see Remold,H.G. Webster,M.E., Clark, W.R. Walsh,R.T., see Barnhardt,M.1. 340 467,520 143,189 Ward, P .A., see Schiffmann,E. Webster,M.E., Guim1i.raes, Walters, M. N.-I.,seeThompson, 120,134 J.A., Kaplan,A. P., Colman, P.L. 112,134 Wardell,J.R., see Chakrin,L.W. R.W., Pierce,J.V. 472,520 Walthert,F., see Bovet,D. 14, 356, 357, 367 Webster,M.E., Guim1i.raes, 20 Wardlaw,A.C., see PiIIemer,L. I.A., Pierce,J.V. 466,472, Walton,K.G., see Delorenzo, 235,264,428,432,459 520 R.J. 306,308 Warner,B.T., see Collier,H.O.J. Webster,M.E., Maling,H.M., Walz,D., see Brune,K. 589, 609 Zweig,M.H., Wi11iams,M.A., 609 Warren,K.S., Boros,D.L. 87, Anderson, W., Jr. 490, 491, Wang,H.M., see Tan,L. 402, 107 502,503,521 422 Warren,K.S., Domingo,E.C., Webster,M.E., Pierce,J.V. Wang,R.W., see Lim,R.K.S. Cowan,R.B.T. 251,265 465,469,471,521 589,594,613 Warren,K.S., see Domingo,E. Webster,M.E., Ratnoff,O.D. Wang,S.C., see Chai,L.Y. 621, C. 251,261 465,471,521 650 Wasserman,K., see Mayerson, Webster,M.E., see Guim1i.res, Wang,S.C., see Schoener,E.P. H.S. 33,66 J.A. 466,511 621,630,631,654 Wasserman, S .1., Austen, K.F. Webster,M.E., see Maling, Wang,S.C., see Wit,A. 629, 362,373 H.M. 480,503,515 656 Wasserman,S. I., Goetzl,E.J., Webster,M.E., see Melmon, Wannamaker,L. W., Matsen,J. Austen,K.F. 286,293, K.L. 491,498,499,515,590, M. 273, 287, 293 302,312 594,600,613 Wansbrough-Jones, M.H., see Wassermann, S .1., see Goetzl, Webster,M.E., see Miller,R.L. Pepys,M.B. 442,459 E.J. 125,131 496,515 Wapshaw,K.G., see Wilkinson, Wasserman,S. I., see Lewis,R.A. Webster,M.E., see Pierce,J.V. P.C. 136 348,350,363,370 464-466,469,516 728 Author Index

Wechsler,A., see Bodel,P.T. Weiss,H.J., Chervinick,P.A., Weissmann,G., see Bourne, 619,650 Zulusky,R., Factor,A. 169, H.R. 305,307 Weddell,G. 591,615 204 Weissmann,G., see Davies,P. Weddell, G., Pallie,W., Palmer, Weiss,H.I., Rogers,J., Brand,H. 268,289,301,308 E. 592,615 166,204 Weissmann,G., see Goldstein,1. Wedner,H.J., see Parker,C.W. Weiss,H.J., Tschopp,T.B., 119, 132, 298, 301, 304, 305, 322,340 Baumgartner,H.R. 165, 309 Weeks,J.R., Wingerson,F. 166,169,204 Weissmann,G., see Goldstein, 627,655 Weiss,H.J., Tschopp,T.B., LM. 268, 269, 271, 286, 290 Weeks,J.R., see Pike,J.E. 410, Rogers,J., Brand,H. 169, Weissmann,G., see Hirschhorn, 420 204 R. 306,310 Weeks,R.E., see Gunnar,R.M. Weiss,H.J., Willis,A.L., Kuhn, Weissmann,G., see HolTstein,S. 504,511 D.C., Brand,H. 156, 166- 272, 291 Wegener,F. 99, 108 171,204 Weissmann,G., see Tsung,P.-K. Wedgwood,R.J., see Pensky,J. Weiss,H.J., see Holmsen,H. 306,317 459 195 Weissmann,G., see Zurier,R.B. Weigert,C. 10,25 Weiss,H.J., see Holmsen,M. 254,266,270,272,294,303- Weigle, W.O., see Cochrane, 169,195 305, 313, 356, 357, 373, 553, C.G. 240, 242, 251,261 Weiss,H.J., see Safrit,H. 171, 567 Weiler,J.M., Daha,M.R., 201 Weksler,B.B., Coupal,C.E. Austen,K.F., Fearon,D.T. Weiss,H.J., see Tschopp,T.B. 176,204 430,448,449,463 165, 166, 169,203 Weksler,B.B., see Nachman, Weiler,J.M., Yurt,R.W., Weiss,H.J., see Willis,A.L. R.L. 176,199, 186, 187,204 Fearon,D.T., Austen,K.F. 149,154,156,158-160,168, Weksler,B., see Nachman,R.L. 463 170, 173, 205 172,176,199 Weiss,L. 111,135 Weiner,R., see Kaley,G. 173, Welaj,P., see Di Pasquale,G. Weiss,L., see Sutton,J.S. 69, 175,196 553,562 107 Weinstein,H., see Green,J.P. Welch,J. P., see Lipton,J.M. Weiss,P. 222,230 361,368 621,626,627,653 Weissbach,H., see Waalkes, Weinstein, Y., Melmon, K. L., T. P. 183,204 Wellek,B.,Opferkuch,W. 434 Bourne,H.R., Sela,M. 359, Weissman,G. 18,25, 184,204, 463 373 286,294 Wells,F.R. 43,45,67 Weinstein, Y., see Bourne,H.R. Weissmann,G., Dingle,J. 482, Wells,F.R., Miles,A.A. 42,46, 345,350,366 521 67 Weinstein,Y., see Melmon,K.L. Weissmann,G., Dukor,P. 303, Welsh,LR.H., Zeya,H.J., 356, 358, 359, 270 312 Spitznagel,J.K. 296,313 Weinstein, Y., see Mozes,E. Weissmann,G., Dukor,P., Welsh,I.R.H., see Folds,J.D. 358,371 Zurier,R. B. 258,265,303, 268,290 Weinstein, Y., see Segal,S. 359, 312 Welsh, I. R. H., see Spitznagel, 372 Weissmann,G., Fell,H.B. 482, J.K. 268,293 Weinstein,Y., see Shearer,G.M. 521 Wemambu,S.N.C., Turk,J.L., 359,372 Weissman,G., Goldstein, T., Waters,M.F.R., Rees,R.J. W. Weisenberg,R.C., Borisy,G.G, HolTstein,S., Chauvet, G., 242,265 Taylor,E.W. 303, 304, 312 Robineaux,R. 18,25, 306, Wendlandt,S., see Dey,P.K. Weiser,C., see Halushka,P.V. 313 621,638,640,642-644,646, 159,194 Weissmann,G., Rita,G.A. 651 Weiser,R.S., see Pearsall, N .N. 551,567 Wendlandt,S., see Feldberg, W. 68,105 Weissmann, G., S pilberg, I., 621,638,641,644,651 Weiss,A.S., Gallin,J.I., Kaplan, Krakauer,K. 299, 313 A.P. 472,521 Weissmann,G., Thomas,L. Wendlandt,S., see Milton,A.S. Weiss,H.J. 138-145, 152, 153, 482,521 375, 419, 617, 621, 623, 264, 158-160, 162-169, 171, 172, Weissman,G., Zurier,R.B., 626,628,630-633,637,642, 179,188,204 HolTstein,S. 25,303,304, 644,653,654 Weiss,H.J., Aledort,L.M. 153, 313, 553, 556,567 Werb,Z., Gordon,S. 273, 280, 204 Weissmann,G., Zurier,R.B., 281,294 Weiss, H. J., Aledort, L. M., Spieler,P.T., Goldstein,LM. Werb,Z., Reynolds,J.J. 281, Kochwa,S. 204 268,270,294 294 Author Index 729

Werb,Z., see Harris,E.D., Jr. West,G.B., see Riley,J.F. 572, White,T.G., Puls,J.L. 255, 281,291 586 265 Werle,E. 470,482,521 West,G.B., seeStarr,M.S. 484, White,T.T., see Morgan,A. Werle, E., Appel,W. 470,521 494,495, 503,519 499,515 Werle, E., Erdos, E.G. 473,421 West,G.B., see Thomas,G. Whitehead, T. P., see Harpman, Werle, E., Forell,M.M., Maier, 489,520 J.A. 595,611 L. 470,471,521 Westberg,N.G., Naff,G.B., Whitehouse, M. W. 549, 567 Werle, E., Kaufmann-Boetsch, Boyer,J.T., MichaeI,A.F. Whitehouse, M. W., see Paulus, B. 469,521 447,463 H. E. 558,565 Whitelaw,D.M. 108 Werle, E., Kehl,R., Koebke,K. Weston,P.D. 300,313 WhiteIaw,D.M., Batho,H.F. 473,521 Weston,P.D., Barrett,A.J., 108 Werle, E., Maier,L. 469,521 Dingle,J.T. 300,313 Whitelaw,D.M., Bell,F.M. Werle, E., Roden,P., von 470, Weston,P.D., see Dingle,J.T. 283,290,300,308 Batho,H.F. 108 521 Whitelocke,R.A.F., see Eakins, Werle, E., Trautschold,L., Weston,W.L., Mandel,M.J., K. E. 175, 192 Krueger, G.G., Claman, H. N. Leysath, G. 465,469,521 Whitfield,J.F., MacManus,J.P., 287,294 Werle, E., Vogel,R. 470,521 GiIIan,D.J. 497,521 Westphal,O. 618, 642,655 Werle, E., see Fiedler,F. 470, Whitfield,J.F., Rixon,R.H., 510 Westphal,O., see Galanos,C. Mackmanus,J. P., Balk,S. D. Werle, E., see Fritz,H. 469,510 618,652 322,341 Werle, E., see Hochstrasser,K. Westphal, 0., see Llideritz,O. Whitefield,J.F., see Perris,A.D. 466,512 618,653 497,516 Werle, E., see Kraut,H. 470, Westphal, 0., see Rietschel,E.T. Withfield,J.F., see Rixon,R.H. 514 618,654 497,517 Werle, E., see Vogel,R. 469, Whaley,K., Ruddy,S. 430,463 Whittaker,N., see Johnson,R.A. 470,520 Wheelock,E.F., see Larke,R.P. 196 Wesp,M., see Krupp,P. 645, B. 187,196 Whittle, B. A. 481,521,603,615 653 Whishaw,I., see Veale, W.L. Whittle,H.C., Abdullahi,M . .J., Wessels,N.K., Spooner,B.S., 627,655 Fakunle,F.A., Greenwood, Ash,J.F., Bradley,M.O., White, A., see Crowder,J.C. B.M., Bryceson,A.D.M., Luduena,M.A., Taylor,E.L., 268,289 Parry,E.H.C., Turk,J.L. Wrenn,J.T., Yamada,K.M. White,A.M., see Butler,K.D. 244,265 140,204 184,191 Whittle, H. c., see Greenwood, Wessels,N.K., Spooner,B.G., White, F., see Leonardi,R.G. B. M. 244,262 Ash,J.F., Bradley, M.D., 153,197 Whitworth, C., see Mohamed, Luduena,M.A., Taylor,E.L. White, I. F., see Curry,F.E. S.F. 152,198 Wrenn,J.T., Yamada,K.M. 582,585 WHO Memorandum 265 269,294 White,J.G. 140,204 WHO Report 244,265 Wessler,S., see Ream, V.J. 184, White,J.G., Krivit,W. 139, Widmann,J.J., Cotran,R.S., 200 204 Fahimi,H.D. 72,108 West, B. C., Kimball,H.R. 296, White,J.G., Witkop,J.G. 170, Wiebkin, O. W., Hardingham, 313 204 T.E., Muir,H. 209,230 West,C.D., see Spitzer,R.E. White,J.G., see Clawson,C.C. Wiebkin,O.W., Muir,H. 209, 430,447,462 186,191 230 West,C.D., see Vallota,E.H. White,J.G., see Davis,R.B. Wienecke,A.A., see Woodin, 430,447,462 141,192 A.M. 124,136 West,G.B., see Brown,R.A. White,J.G., see Estensen,R.D. Wiener, E., see Cohn,Z.A. 282, 540,555,562 268,290,298,308,313 289 West,G.B., see Dawson, W. White,J.G., see Gerrard,J.M. Wiener,J., Lattes,R.G., Pearl, 494,495,503,508 140, 155, 170, 171, 179, 193 J.S. 51,67 West, G.B., see Feam,H.J. White,J.G., see Glass,D.B. Wiener,J., Latters,R. G., Spiro, 556, 557, 563 160,193 D. 51,67 West,G.B., see Harris,J.M. White,R.G., Estensen,R.D. Wiener,J., see Giacomelli, I. 580,585 268,294 36,64 West,G.B., see Parratt,J.R. White,R.G., see Russell,R.J. WilheIm,D.L. 16,25,475,477, 505,516,575,586 120,133 478,498,521,573,579,587 730 Author Index

Wilhelm,D.1., Mason,B. Williams,T., see Granger,G.A. Willis,A.1., see Smith,J.B. 486, 504, 522, 575, 579, 577 279,290 153, 160, 169, 171, 173, 177, Wilhelm, D. 1., Mill, P. J., Williams, T.J. 162,205, 327, 178,202,575,586,606,615 Sparrow, E. M., McKay, M. E., 341, 581, 583,587 Willis,A.1., see Weiss,H.J. Miles,A.A. 478,522 Williams, T.J., Granger,G.A. 156,166-171,204 Wilhelm,D.1.,seeCarr,J. 477, 330,341 Willms-Kretschmer,K., see 478,507 Williams, T.J., Morley,J. 59, Lepow,1.H. 345,348,351, Wilhelm,D.1., see Freund,J. 67,173,205,326,342,582,587 370 Wilms-Kretchmer,K., see 477,478,510 Williams, T.J., see Morley,J. ShetTer,A.1. 439,449,461 Wilhelm, D. 1., see Miles,A. A. 314,319,326,340 Willoughby,D.A. 6, 18, 19,25 16,23,477,478,515 Williamson, E., see Maudsley, Wilhelm,D.1., see Sparrow, Willoughby,D.A., Boughton, D. V. 365,370 B., Spector, W. G., Schild, E. M. 477,478, 505,519 Willies,G., see Laburn,H.P. H.O. 315,342,571,587 Wilhelm,D.1., see Steele,R.H. 633, 635, 636,653 29,66 Willoughby,D.A., Coote,E., Willies, G. H., see Laburn, H. Wilkinson, Parrott, Russell, Turk, J. 1. 536, 567 633,653 SIess 136 Willoughby,D.A., Ryan,G.B. Willis,G.H., see Woolf,C.J. Wilkinson,P.c. 109, 117-125, 252,265 631, 635, 636, 656 127,135 Willoughby,D.A., see Berry, Wilkinson, P. C., Basel,J. F., Willis,A.1. 138,146,151,153- H. 253, 255, 260 Stecher-Levin, V.J., Sarkin,E. 154,156-158,168,169,171, Willoughby, D. A., see Capasso, 176,205 175,205,488,522,572,573, F. 257,261 Wilkinson, P. C., McKay,!. C. 587,604,615 Willoughby,D.A., see Deporter, 121,135,136 Willis, A. 1., Comai,K., Kuhn, D.A. 259,261 Wilkinson,P.C.,O'Neill,G.J. D.C., Paulsrud,J. 382,422 Willoughby, D. A., see Dieppe, McInroy,R.J., Cater,J.C., Willis,A. 1., Cornelsen, M. P.A. 258,259,261 Roberts,J.A. 119, 120, 125, 173,205,600,601,615 Willoughby, D. A., see Di Rosa, 126,136 Willis, A. 1., Davison, P., M. 488, 502, 503, 508, 527, Wilkinson,P.C.,O'Neill,G.J., Ramwell, P. W., Brockle• 528, 530, 536, 562 Wapshaw,K.G. 136 hurst, W. E., Smith, B. 153, Willoughby,D.A., see Giroud, Wilkinson, P. c., Roberts,J. A., 168, 170, 175, 177,205, 627, J.P. 259,260,262,542,563 Russell,R.J., McLoughlin,M. 631,645,646,655 Willoughby,D.A., see Hurley,J. 120,136 Willis,A.1., Kuhn,D.C. 141, V. 46,65 Wilkinson, P.C., see Russell,R.J. 153, 157,205 Willoughby,D.A., see Schild, 117, 120, 124, 128, 133 Willis,A.1., Kuhn,D.C., Weiss, H.O. 331,341 Wilks,J., see Glenn,E.M. 181, H.J. 141,154, 156, 158-160, Willoughby,D.A., see Spector, 193 173,205 W.G. 29,45,61,66,482,486, Wille, G., see Bartels, J. 380, Willis,A.1., Stone,K.J. 157, 502, 504, 505, 519, 540, 555, 415 172,178,205 566,575,579,586 Willoughby,D.A., see Velo, Willers,J. M. N., see Kerck• Willis,A.1., Vane,F.M., Kuhn, G.P. 257,265 haert,l. A. M. 250, 263 D. c., Scott, C. G., Petrin, M. Willoughby,D.A., see Turk,J. 1. Williams,D.G., see Peters,D.K. 141,146,154-159,164-166, 231,265 447,459 168, 169, 175, 178, 181, 188, Willoughby,D.A., see Yama• Williams,G., see Jackson,D.S. 205,387,422,601,615 221,228 moto,S. 255,257,258,265 Willis,A.1., Weiss,H.J. 149, Williams,l., see Epps, D. E., van Wilson,1., see Mizel, S. B. 269, 154, 159, 160, 166, 168, 170, 292 137 173,205 Williams,M.A., see Maling, Windaus,A., Vogt, W. 13,25 Willis,A.1., see Anderson,A.J. H. M. 480, 503, 515 Winder,C. V. 597, 601-603, 177,189 Williams, M.A., see Webster, 605,606,615 M.E. 490,491,502,503,521 Willis,A. 1., see Crunk horn, P. Winder,C.V., PfeitTer,C,c., Williams,N., see Moore,M.A.S. 17,20, 173, 175,192,574,585, Maison,G.1. 601,605,616 76,93,105 598,610 Winder,C.V., Wax,]., Been, Williams,R.C., see Holley,T.R. Willis,A.1., see Farrow,J.F. M.A. 582,587 126, 132 145,193 Winder,C.V., Wax,]., Burr,V., Williams,S., see Davies, P. 227, Willis,A.1., see Kuhn,D.C. Been,M., Rosiere,C.E. 531, 289 173,196,600,612 567 Author Index 731

Windhorst, D. B., see Moncada, Wolfe,L.S., see Coceani,F. Woodin,A.M. 120,136 B. 426,458 393,416 Woodin,A.M., Wieneke,A.A. Window,J., see Casley-Smith, Wolfe,L.S., see Pace-Asciak,C. 124,136 J.R. 583,584,585 393,420 Woodruff,J., Gesner,B.M. Wingerson,F., see Weeks,J.R. Wolff,H.G. 606,616 112,136 627,655 Wolff,H.G., Hardy,J.D., Woodward, C. L., see Greisman, Winkelstein,J.A., Smith,M.R. Goodell,H. 601, 605, 616 S.E. 619,652 Shin,H. S. 444,463 Wolff,H.G., see Chapman,L.F. Woodworth, H. C., see Klem• Winkler,H., see Smith,A.D. 492,507,594,595,609 perer,M.R. 428,456 177,201 Wolff,H.G., see Hardy,J.D. Woodworth, R. S., Sherrington, Winne,D. 529,567 531, 533, 564, 591, 595-597, C.S. 589,616 Winter,C.A. 602,603,616 611 Wooley, G., see Hall,J.G. 59, Wolff,S.M., Kovats,T.G. 247, 64 Winter,C.A., Flataker,L. 480, 265 Woolf,C., see Laburn,H.P. 522, 531, 567, 597, 602, 603, Wolff,S.M., see Dale,D.C. 633,635,636,653 616 72,88,101 Woolf,C.J., Willis,G.H., Winter,C.A., Nuss,G.W. 504, Wolff,S.M., see Fauci,A.S. Laburn,H., Rosendorff,C. 522 99,102 631,635,636,656 Winter,C.A., Risley,E.A., Wolfram,C.G., see Mayerson, Nuss,G. W. 487,504,522 Woolf,C.J., see Laburn,H. H.S. 33,66 633,653 Winter,C.A., see Arman,C.G., Wolley,D.W., see Stewart,J.M. van 480,503,504,520,602, Work,E. 618,656 500,519 Work,T., see Lewis,G.P. 605,615 Wolstencroft, R. A., Dumonde, Winternitz,R. 529, 534, 567 465,470,514 D.C. 320--322,342 World Health Organization Wintrobe,M.M., see Boggs, Wolstencroft,R.A., see Bray, D.R. 95,100 463 M.A. 320,325,327,332,333, Wrenn,J.T., see Wessells,N.K. Wintrobe,M.M., see Scott,J.L. 337 140,204,269,294 165,201 Wolstencroft,R.A., see Wright,D.G., Gallin,J.1. Wiqvist,N., see Green,K. 402, Dumonde,D.C. 77, 101, 301,313 417 317,321,331,338 Wright,D.G., Malawista,S.E. Wiseman, E. H., Chang, Y. Wolstencroft,R.A., see 287,294,303,304,313 178,181,205 Franco, M. 328,338 Wright,H. P. 147,205 Wisse,H. 72,108 Wolstencroft,R.A., see Wright,L.J., see Gillman, T. Wisse, E., see Deams, W. T. 72, Kelly,R.H. 319,331,339 69, 103 101 Wolstencroft,R.A., see Morley, Wright,N.J., see Parmley,R.T. Wissler,lH. 234,265 J. 317, 320, 331, 334, 340 348,371 Wissler, I. H., Stecher, V.I., Wong,S. c., see Sampaio,C. Wright, V.A., see Cranston, W.1. 470,518 Sorkin,E. 118,136 641,651 Wood,G.C., see Pryce-Jones, Wit,A., Wang,S.c. 629,656 Wuepper,K.D. 18, 25, 472, Witkop,J.G., see White,J.G. R.H. 302,311 522 Wood,J.E., see Grant,R.T. 170,204 Wuepper, K. D., Bokisch, V. A., Witkum,P.A., see Flores,J. 54,64 Miiller-Eberhard,H.J., Wood, W.B., see Allison,F. 305,308 Stoughlon,R.B. 234,265 111, 124, 128, 129 Witz,J. P., see Keisari, Y. 300, Wuepper,K.D., Lawrence, Wood,W.B., see Shin,H.S. 310 T.G., Cochrane,C.G. 472, 436,445,461 Wlodawer, P., Samuelsson, B. 522 Wood, W.B., Jr., see Allison,F., 386, 387, 394, 422 Wuepper, K. D., Miller, D. R., Jr. 28,49,62 Wlodawer, P., see Marnett, L. 1. Lacombe,M.J. 472,522 Wood, W.B., Jr., see King,M.K. 401,419 620,653 Wuepper,K.D., Tucker III, Woessner,J.F., Jr. 482,522 Wood,W.B.,Jr., see Murphy, E.S., Cochrane,C.G. 522 Wohlenberg,C., see Snyder• P.A. 619,654 Wuepper,K.D., see Cochrane, man,R. 119,134 Wood, W.B., Jr., see Rafter, c.G. 472,507 Wohler,I.M., see Erdos,E.G. G.W. 619,654 WuIlf,D.L., see Bennett,]. 473,509 Woodbury,D.M. 602,616 382,416 Wohler,J.R., see Erdos,E.G. Woodcock,J., see Stanley,E.R. Wyatt,H.V., Colten,H.R., 473,496,509 95,107 Borsos, T. 428,463 732 Author Index

Wyche, A., see Needleman,P. Yeh,H.S.J., see Kakimoto,T. ZeJigs,J. D., see Janoff,A. 301, 154,157,199 302,310 310 Wyllie,1.H., see Gilmore,N. Yellin, T. 0., Sperow,J. W., Zeman,N., see Vogt,W. 440, 152,193 Buck,S.H. 354,373 462 Wyllie,J.H., see Piper,P.1. Yin,H.H., see Berlin,R.D. Zembala, M., Asherson, G. L. 409,421 115,130 250,251,266 Yonemasu,K., Stroud,R.M. Zeya,H.I., Spitznagel,J.K. 426,463 184,205,303,313 Xeros,N., see Hurley,1. V. 51, Yonemasu, K., see Shelton, E. Zeya,H.I., see Herion,1.C. 426,461 65 303,309 Yoshida, T., Cohen, S., Zeya,H.J., see We1sh,I.R.H. Bigazzi, P. E., K urasuzi, T., 296,313 Asmden,A. 320,342 Ziboh, V.A., see Hsia,S.L. 606, Yaksh,T.L., see Myers,R.D. Yoshida, T., Janeway,c.A., 612 621,625,654 Paul, W. E. 317,342 Ziccardi, R. l., Cooper, N. R. Yam,L.T., Li,C.Y., Crosby, Yoshida,T., see Thrasher,S.G. 426,436,463 W.H. 70,108 121,134 Ziegler, F. G., Lohmann• Yamada,K.M., see Wessells, Yoshida,T., see Ward,P.A. Mathes, M.-L. 319,325, N.K. 140,204,269,294 345, 348, 359, 373 339 Yamafuji,K., see Greenbaum, Yoshimoto,A., Ito,H., Tomita, Ziegler,]. B., Alper, C .A., L.M. 300,309,473,495,496, K. 395-397,422 Rosen,F.S., Lachman, P.l., 511 Yoshinaga,K., see Abe,K. Sherington,L. 430, 463 Yamamoto,!., see Inoki,R. 499,506 Zieler 7 491,513 Yoshinaga, M., see Hayashi, H. ZifT, M., see Andreis, M. 259, Yamamoto,S., Dunn,C.J., 120, 132, 537, 564 260 Capasso, F., Deporter,D.A., Yoshitake,J., see Senda,N. ZifT,M., see Cooke,T.D. 285, Willoughby,D.A. 258,265 113, 124, 134 289 Yamamoto,S., Dunn,C.l., Youlten,L.J.F., see McCall,E. ZifT, M., see Ishikawa, H. Deporter,D.A., Capasso,F., 173, 175, 197 285,291 Willoughby,D.A., Huskis• Youlten,L.J.T., see Higgs,G.A. ZifT, M., see Stastny, P. 224, son, E. C. 257,265 175,195 230,255,256,264 Yamamoto,S., Dunn,C.J., Young,D., see Chakrin,L.W. Zigmond,S.H. 117,136 Willoughby,D.A. 255,257, 356,357,367 Zigmond,S.H., Hirsch,J.G. 265 Young,1. D., see Spitler, L. 113, 116, 117, 124, 136, 269, Yamamoto,S., see Capasso,F. 332,341 294 257,261 Yurdin,D.L., see Zeiger,R.S. Zigmond,S.H., see Showell, Yamamoto,S., see Hayashi,H. 353,373 H.1. 122,134,137 120,132 Yurt,R.W., see Weiler,J.M. Zijlstra,F.J., see Vincent,J.E. Yamamoto,S., see Miyamoto, 463 159,203 T. 382,394,419 Zimmerman, T .S., Arroyave, Yang,H.Y.T., Erdos,E.G. C.M., MUller-Eberhard, 473,522 Zabucci,G., see Rossi,F.,76, H.1. 443,463 Yang,H.Y.T., see Erdos,E.G. 106 472-474,503,509 Zaher,C., see Chakrin,L.W. Zimmerman,T.S., Kolb,W.P. Yang, S. Y., see Ballow, M. 442, 356, 357, 367 443,463 450 Zaidi,S.H. 98,108 Zimmerman, T .S., MUller• Yang, Y.Z., Perdue,1. F. 269, Zalesky, M., see Braude, A.1. Eberhard,H.J. 184, 205, 294 185,191,621,650 442,463 Yano,M., Nagasawa,S., Hori• Zarco,R.M., see Maillard,1.L. Zinkernagel, R. M., see Bianden, uchi, K., Suzuki, T. 466, 469, 241,263 R.V. 76,100 522 Zarling,1. M., see Tevethia,S.S. Zinsser,H. 231,266, 314, 342 Yano,M., see Suzuki,T. 465, 77, 107 Zinsser,H., Mueller,l.H. 231, 466,469,519 Zeiger,R.S., Yurdin,D.L., 266 Yaron,A., see Schlossman,S.F. Colten,H.R. 353, 373 Zirnis,P., see Vargaftig,B.B. 238,264 Zeigler,E. 25 146,153,157,203 Yasmean,D., see Ellerson,J.R. Zeitlin, I. 1., see Brocklehurst, Zmuda,A., see Dembinska• 426,453 W. E. 468, 507 Kiec,A. 607,610 Author Index 733

Zottermann,Y., see Lewis,T. Zulusky,R., see Weiss,H.J. Zvailler,N.J., see Kravis,T.C. 13,22 169,204 356,369 Zuber,M., Sache,E. 470,522 Zurier,R.B. 346,364,373 Zvailler,N.J., see Pekin,T.J.. Jr. Zuberi,S., see Nugent,F.W. Zurier,R.B., Hoffstein,S., 445,446,459 467,499,516 Weissmann,G. 270, 272, Zvailler,N.J., see Ward,P.A. Zucker,M.B. 172,176,179, 294, 303, 30~313, 553,567 301, 312, 446, 463 186,205 Zurier,R.B., Krakauer,K. Zweifach,B.W. 474,475,477, Zucker,M.B., Grant,R.A. 295 522 161,205, 443,463 Zurier,R.B., Weissmann,G. Zweifach,B.W., Nagier,A.L. Zucker,M.B., Pert,J., Hilgart• 254,266 Troll,W. 502,522 ner,M.W. 166,205 Zurier,R.B., Weissmann,G. Zweifach, B. W., see Ascheim, E. 28,62 Zucker,M.B., Peterson,J. 141, Hoffstein,S., Cameron,S., Zweifach,B.W., see Chambers, 160,205 Tai,H.H. 356, 357, 373 Zucker,M.B., see Marcus,A.J. R. 27,49,63 Zurier,R.B., Weissmann, G., 162, 163, 165, 197 Zweifach,B.W., see Janoff,A. Hoffstein,S., Kammerman,S., Zucker,M.B., see Nagayama, 111,112,132,184,196,302, Tai,H.H. 303-305, 313 M. 184,199 310 Zucker, M . B., see Tschopp, T.B. Zurier,R.B., see Boume,H.R. Zweig,M.H., see Webster,M.E. 169,203 305,307 490,491, 502, 503, 521 Zucker-Franklin, D., Bloom• Zurier,R.B., see Weissmann,G. Zweiman,B., see Slott,R.1. berg, N. 140, 205 258,265,268, 27~294,303, 345,373 Zucker-Franklin, D., see 304,312,313,553,556,567 Zwet,T.L. van, see Furth,R. Marcus,A.J. 272, 292 Zvailler,N .J. 446,463 van, 72, 76, 102 Subject Index

Abcess, see ulcer n-Acetyl-l-tyrosyl ethylester Acetaminophen complement inhibitor 448 analgesic effect 606, 607 Acid hydrolase anti-Bk effect 501 autolysis and 482 antipyretic effect 621, 631, 638, 639, 641, drug effects on 286--288 643,645,646 release induced by complement-sufficient brain PG synthetase and 607,645,646 anti-serum 285 platelet PG synthetase and 153 release induced by immune complex 285 Acetic acid release from macrophage 76,77,273-280 counter-irritant 532 release, mechanism of 267-270, 304 n-Acetyl-p-aminophenol, see acetaminophen release from PMN 268-270, 296, 298, 299 Acetylcholine Acid phosphatase cGMP elevation 556 in PMN lysosome 296 hypothermic effect 627 oedema formation inhibition 482 inflammatory mediator 12 release 304 inflammatory mediator release and 350 Acid proteinase, see also cathepsin pain induction 593, 601 inflammatory mediator 299-301 Acetylsalicylic acid, see also aspirin-like drug; Actin salicylate acid hydrolase retention and 269 analgesic effect 601,602,606,607 leucocyte locomotion and 124 anti-BK effect 501,504 scar contraction and 223 antihaemostatic effect 153 Actinomycosis antipyretic effect 638,639,641 lesions 62 antithrombotic effect 153 Activating factor 392 carrageenin antagonist 504 Actomyosin counter-irritant 558 contraction by direct vascular injury 47 cyclo-oxygenase inhibition 179, 383 Dupuytren's Contracture and 224 endoperoxide synthesis inhibition 156,158, endothelial gap formation and 36, 38 161, 188 scar contraction and 223, 224 graft rejection and 188 Acupuncture 533, 534 hydrolytic enzyme release and 287 Acute inflammation, see also inflammation; kinin-forming enzyme inhibition 502 inflammatory reaction kininogen level and 469 collagenase from PMN and 280 lymphocyte reactivity and 333 counter-irritation and 527-529 platelet aggregation inhibition 146, 148, endogenous antigen and 252, 253 153, 156, 158, 160, 179, 188 homeostasis and 525 platelet PG synthetase inhibition 146, 153, immune complex induced 251 179,401 mediator from platelet 173 PG fever and 631 monocyte production in 86 PG inactivation and 413,414 mononuclear phagocyte and 84-86,95-97 PG synthesis inhibition 179,335,400,401, non-immunological, platelet and 181 607 progression to chronic inflammation, protein acetylation 179, 383 inhibition of 579 n-Acetyl-l-tyrosine methylester scar formation and 209 complement inhibitor 448 vascular event 571,580-584 736 Subject Index

Acute phase reactant Alkaline phosphatase increased synthesis by trauma 468 release from PMN 268,269, 296 inflammatory modulator 548 Allergic arthritis, see also adjuvant arthritis; Adenosine Glynn arthritis 253-256 platelet aggregation inhibition 155, 156 in swine 256 Adenosine diphosphate (ADP) Allergic vasculitis 242 direct aggregating agent 148, 150, 151 Allergy haemostasis, and 163 histamine and 12-15, 17 in PMN dense bodies 141 IgE antibody and 347 platelet shape change response 144, 145, Alphanaphthyl thiourea (ANTU) 150 pulmonary oedema, vascular leakage and release by PGG2 157, 163 42,46 second phase aggregation response 141, Amidopyrine 145, 146, 148, 156, 158, 159 Bk-induced bronchoconstriction and 501 vasoconstrictor 164 Bk-induced pain and 481 Adenylate cyclase plasmin inhibition 502 activation by PGE1 150,350 Amino acid sequence inhibition by aggregating agents 151-153 of collagen 216,217 mediator release and 350 Aminopeptidase platelet membrane and 139 Bk formation 466 Adjuvant arthritis kininase activity in pancreas 473 253,254 {3-Amino propionitrile counter irritation and 529 collagen effect on 217 kininogen level in 503 Amplification convertase 431 liver involvement 549 Analgesia oestrogen effect 551 measurement of 588-590,596---598 suppression by PGE1 254,554 mechanism of 589,590,601-607 suppression by cold stress 557 Analgesic agent, see also specific agents theophylline effect 554 weak, mechanism of action 588, 597, 600, Adrenaline 601-608 anti-inflammatory effect -350, 540, 555, 556 narcotic 601 cAMP elevation 350, 556 Anaphylatoxin, see also C3a, C5a counter-irritation and 540,541 biological activity 234, 440 direct aggregating agent 148, 151, 152 histamine release 13, 15,234,351,440 kininogen level and 469,496 production by complement classical path- platelet sensitization 151 way 233,234 pro-inflammatory effect 555 production by complement alternative second-phase aggregation 139, 141, 145, pathway 235 146, 148, 156, 158, 159 shock 13 Adrenal steroid theory 13 inflammatory modulator 549, 550 Anaphylatoxin inactivator (AI) 436 iJ(-Adrenoceptor Anaphylaxis 345-365 mediator release and 350, 363 anti-histamine agents and 13-15,183,364 platelet aggregation and 152 attenuation by hyperglycemia 551 pro-inflammatory involvement 350, 555 Bk and 15, 494 {3-Adrenoceptor cutaneous 231 anti-inflammatory involvement 556 dextran and 485, 579 histamine release and 350 histamine and 12-14,17,183,346, platelet disaggregation and 152 354--356,364,494 stimulation, cAMP elevation and 350, 556 history 12-17 Adrenocorticosteroid 5-HT and 15, 183, 346, 361, 364, 494, 579 inflammatory modulator 550 IgE antibody and 231, 233, 346, 347, 360 Afibrinogenemia 165 immunological aspects 183, 231, 232, 345, Agar 493 kininogen depletion 467 kininogen level and 495, 503 Shwartzman reaction and 236, 245 mediator release, mechanism of 349-352, Algogenic substance 480, 481 363 Subject Index 737

platelet aggregation and 183 reaginic, Arthus reaction and 240, 241 serum 12 reaginic, ECF-A release and 127 SRS-A and 346, 362, 364, 494 reaginic, immediate hypersensitivity and thermic oedema and 485 231,346 Anaphylactic shock reaginic, PCA and 182,183 Bk and 494 reaginic, wheal and flare reaction and 346 histamine and 14 rheumatoid arthritis and 445, 498 platelet and 183 secretion by B-lymphocyte, inhibition by Angiotensin histamine 356, 358 pain induction 593 sensitization, PCA and 182 Angiotensin C specificity 237 in lysosome 302 SRS-A release and 362 Angiotensin converting enzyme 473 vascular events of inflammation and 584 Antergan, see phenbenzamine 1'1 Antibody, see immunoglobulin G 1 (IgG 1) Anterior hypothalamus Antibody-dependent cellular cytotoxicity PGE1 febrile activity, site of 624 (ADCC) PGE 1 injection 626,628 PMN and 305 temperature sensitive neurone 629, 630 Antibody-mediated immunity unspecific fever and 636 anaphylaxis and 231 Antibody, see also immunoglobulin Arthus reaction and 231,234,235 anaphylaxis and 493 complement and 233 cartilage autolytic degradation and 283 delayed-in-onset hypersensitivity and 250, cellular cytotoxicity and 305 251 complement activation 240, 241, 432, 437 history 314 complement activation, autoimmune disease lymphokine and 331 and 445 transfer of 249 cytophilic, antigen-specific migration and Anti-Bk agent 500, 501 119,122 Antidromic stimulation cytophilic, delayed-in-onset hyper• inflammatory modulator release 556-558 sensitivity and 251 Anti-enzyme cytophilic, ECF-A release and 127 inflammatory modulator 546, 560 cytotoxic (Type II) hypersensitivity and Antigen, see also immune complex 283 anaphylactic shock and 183,494 delayed hypersensitivity and 314 anaphylaxis and 493, 494 endotoxin reaction and 185 Arthus reaction and 239,240,315 histamine release and 352, 360 cell migration and 315 histamine-induced vascular permeability cell-mediated immunity and 237, 493 and 365 cell-mediated immunity, local passive homocytotropic - see reaginic transfer and 237 humoral, delayed-in-onset hyper• delayed hypersensitivity and 247,248,314, sensitivity and 250,251 315, 326, 332, 334 humoral, granuloma formation and 251 Glynn arthritis model and 254, 255 humoral, immediate hypersensitivity and histamine release and 349, 351, 356, 359, 231,232 363 humoral, skin reaction and 231 immediate hypersensitivity and 346 Jones-Mote reaction and 314 immune reaction and 493 mast cell binding 347 immunoglobulin binding to Clq and 426 precipitating, against factor VIII 166 immunopathogenic mechanism and 346 precipitating, Arthus reaction and 235, immunosuppression and, inhibition by 240,241 histamine 358 precipitating, PCA and 182, 183,235 Jones-Mote reaction and 248,314 production, antigen recognition and 237 lymphocyte activation 118, 119, 239, 316, production, by mononuclear phagocyte 76 317,322,324,334 production, carrier specificity and 238 lymphocyte activation, inhibition by production, C3 and 442 glucocorticosteroid 333 production, lymphokine and 331 lymphocyte chemotaxis and 136 production, opsonisation and 12 lymphocyte DNA synthesis and 321 738 Subject Index

Antigen, lymphocyte migration and 316 mode of action 334, 335, 579 lymphocyte transformation and 238, 322 protein breakdown inhibition 482 lymphocyte transformation, inhibition by Anti-inflammatory humoral factor histamine 358 counter-irritation and 536--541,559 lymphokine biological activities and 317 Antilymphocyte serum (ALS) lymphokine cytotoxic activity and 330 inflammatory modulator 545 lymphokine heterogeneity and 332 Antimitotic agent, see also chalone; colchicine; lymphokine migration inhibitory activity vinblastine and 320, 324 collagen formation and 220 lymphokine mitogenic activity and 320, tissue regeneration and 207 321 Anti-phospholipase agent 411,412 lymphokine osteoclast activation and 330 Anti-platelet serum lymphokine production and 239, 252, inflammatory response 182 316--318,331,334 Antipyretic agent lymphokine production method and non-specific fever and 642 319-321 PG fever and 617, 630-632 macrophage migration and 316 PG synthesis inhibition 631, 637, 646 macrophage migration inhibition and 317 pyrogen fever and 621,645 macrophage migration, inhibition by Antirheumatic agent, see also individual drugs histamine 358 assay 255, 259 mediator release, CBH reaction and 359 mode of action 558 mediator release, IgE interaction and Antithrombin III 347-349,351,365 plasma kallikrein inhibition 470 mediator release, inhibition by histamine IXl-Antitrypsin 357 plasma kallikrein inhibition 470 mediator release, relative proportions and Antrypol, see suramin sodium 364 Aprotinin mitogenic effect 321 anti-proteasic action 482 presentation by macrophage 77 Bk-inhibition 484,502 PG production and 334 carrageenin oedema and 489 recognition in cell-mediated immunity kallikrein inhibition 470 237 pancreatitis and 500 serine esterase activation 349 urate oedema and 489 specificity in cell-mediated immunity 237 Arachidonic acid SRS-A release and 362, 363 biosynthesis 379 suppressor cell and 249,250 cyclo-oxygenase substrate 380, 382-384 wheal and flare reaction and 346 distribution 381 Antigen/antibody complex, see immune endoperoxide formation and 178, 179, complex 385,386 Antihistamine agent HPETE/HETE formation and 385, 404, anaphylaxis and 13--15,364 405 histamine receptor and 353, 354 inflammatory response 182 inflammatory mediator and 575, 578 lipoxygenase substrate 404,405 serum sickness and 360 minor oxidation products 392, 393 urate oedema and 490 nomenclature 377 Anti-human serum albumin (HSA) platelet aggregation and 146, 153, 156, 158 chemotactic effect 119, 128 pro-inflammatory effect 146, 182,375 Anti-inflammatory agent, see also specific PGDH inhibition 413 drugs thromboxane formation and 391, 392 anti-Bk effect 17, 501 Argyrophilia assay 256,258-260 of hypertrophic scars 223 auto modulation and 558, 559 of reticulin 221 experimental inflammation and 256--269, Arteriolar constriction, see vasoconstriction 504,505,579 Arteriole, see also microcirculation; small kinin formation inhibition 502 blood vessel lysosomal enzyme release inhibition blood flow in 27, 28, 39 286--288 constriction after injury 28,29 Subject Index 739

dilation alter injury 28, 29 Axial flow, see also laminar flow; vascular flow in normal microcirculation 27 27,28 leakage, direct vascular injury and 45 Azathioprine Arthritis, see also adjuvant arthritis; monocyte production and 81, 82, 90-92 rheumatoid arthritis Azurophil 268, 270, 296 experimental 253~256, 487 infection and 244 Bacille Calmette-Guerin (BCG) vaccine serum sickness and 244 adjuvant arthritis and 253 Arthus reaction delayed hypersensitivity and 247, 249 clinical 242 Bacterial lipopolysaccharide, see endotoxin complement and 233,235,443,444 Bacterial pyrogen, see endotoxin experimental 239~242, 257 Bacterial toxin history 12 leucocyte locomotion and 122, 126 immunological aspects 231,232,234,235 vascular permeability and 46 platelet and 183,184 Basement membrane pleural cavity and 257 collagen Type IV and 217 reversed passive 240,241,257 injury and 42 Arylsulphatase leucocyte migration and 52~54 SRS-A inactivation 302 lymphatic 57, 58 Ascorbic acid molecular sieving 54 collagen formation and 220 of small blood vessel 31 ~ 33 PG biosynthesis and 395 scar formation and 211--213 Aspartic acid Basophil in collagen 218 chemotactic factor release 345, 348, 350, Aspirin, see acetylsalicylic acid; salicylate 351 Aspirin-like drug, see also individual drugs chemotaxis 345, 365 analgesic effect 589,590,597,601--608 delayed hypersensitivity and 248~250, anti-Bk effect 501 345, 360 anti-cyclo-oxygenase activity 374, 387, histamine effect 356, 357 391,394 histamine release 345, 347~352, 357, 359, anti-inflammatory effect 374 360 antipyretic effect 607 5-HT release 361 assay 589 immediate hypersensitivity and 347--352 central mode of action 607, 608 IgE receptor 347 HHT formation inhibition 387 Jones Mote reaction and 359 migraine and 606 kallikrein release 345, 348, 350, 351 peripheral mode of action 602--607 platelet activating factor release 348, 361 PGDH inhibition 413 PG release 345, 348 PG synthetase inhibition 580 SRS-A release 345,348,351,363 PHD formation inhibition 391 Basophil kallikrein of anaphylaxis (Bk-A) platelet aggregation and 141, 158~160 348,350,351 Asthma Benadryl (T), see diphenhydramine hydro• histamine and 14, 15 chloride Astrocyte 226 Benzamidine Atropine complement inhibitor 448 fever and 634, 646 Bernhard Soulier syndrome 163, 166 histamine theory and 12, 14 Blister techniq ue 480 Autoimmune disease Blood-brain barrier complement deficiency and 444 pyrogen and 621,622,646 inflammation and 252~256 Blood clotting Autoimmune haemolytic anaemia 445 complement alternative pathway and 184, Automodulation 235,236 therapy and 558~560 endotoxin and 184, 185,235,236 Autonomic reflex heparin and 176, 185 pain/analgesia measurement 589, 590 5-HT and 360,361 Autopharmacology kinin and 176, 177,472 history 12 mechanism 162 740 Subject Index

Blood clotting macrophage origin and 77, 78, 80, 86 platelet and 162, 176, 177 monocyte production in 89, 93-96, 98 platelet coat and 139 mononuclear phagocyte kinetics and 82 Blood flow, see also axial flow; laminar flow; mononuclear phagocyte origin and 79 vascular stasis mononuclear phagocyte system and 97 blood viscosity and 29 platelet origin and 138 Bk effect 16, 17 Bradykinin (Bk), see also kinin delayed hypersensitivity skin reaction and adrenaline release 555 326 anaphylaxis and 15,348,494,495 histamine effect 28 anti-Bk agent and 17,500,501 lymphokine induced erythema and 327 blood pressure effect 16 measurement in inflammation 580, 581, bronchoconstriction 181, 376, 465, 499 583 bronchospasm 465 measurement, physiological 581 counter-irritation and 530, 532 microcirculation and 27 drug effects 500-505 normal 27 electrical stimulation and 491,492 plasma protein extravasation and 583 formation 465--467 PO effect 583 formation, inhibition of 502, 503 regulation of 27-29 half-life 472 temperature and 17,580,581 inactivation 472--474 tissue activity and 27, 28 infection and 492,493 tissue injury, initial response and 26-29 inflammatory mediator 16, 17, 346, 374, tissue pressure and 29 474, 573-575 vascular permeability and 29,574,581,583 leucocyte accumulation and 482 Blood platelet, see platelet lymph, effect on 486, 487 Blood pressure mitotic activity 497 Bk and 16 oedema formation 16, 17, 465, 480, 481, histamine and 14 589, 590, 592-594, 596, 598---608 inflammation and 579, 583 phospholipase stimulation 380 kinin and 478 potentiation by drugs 503 measurement 581, 582 potentiation by 5-HT 17 trypsin and 15 potentiation by polypeptide 482 Blood viscosity PO release 488, 606 vascular permeability and 29 pseudo effective response and 16 B-lymphocyte relative potency 479 antibody-mediated immunity and 352 release by kininogenase 345, 469--471 antibody production, C3 and 442 release by trauma 482--495 C3 receptor 442 synthesis 464 chemotactic factor release 442 thermic oedema and 484--486 complement and 442 urate oedema and 491 cyclophosphamide depletion 249 vascular permeability, effect on 16, 17, 36, histamine effect 356, 358 465,475,477,478,486,574,583 histamine receptor 358 vasodilation 16, 17, 465, 474, 477, 574, 590 homeostasis and 250 Bradykinin-like activity 464, 465, 473 lymphokine production 332 Bradykininogen (Bkg) lysosomal enzyme release and 273, 277 inflammatory mediator 16, 17 macrophage, effect on 273, 277 Bradykinin-potentiating factor (BPF) maturation, inhibition by histamine 358, 484, 503, 576 360 BPP9a 488 proliferation, C3 and 442 Bradykinin-system, see also plasma-kinin; Body temperature kininogen inflammation, effect on 579 kininogenase, kininase 464-505 PO effect 617,623---629,646,647 Bronchial asthma Bone kinin activity 499 repair 225 Bronchoconstriction Bone marrow by arachidonic acid metabolite 375 haemopoietic stem cell and 74 by Bk 181,376,465,499 Subject Index 741

by 5-HT 361 Carboxypeptidase B by plasma kinin 465, 499 Arthus reaction and 301 by PG 376 kininase activity 300, 473, 474, 495, 503 platelet and 181, 182 kininogen and 466 Bronchospasm lysosomal acid cathepsin 299 plasma-kinin and 465 urate oedema inhibition 490,491 Burimamide Carboxypeptidase N (kininase I) histamine-type 2 antagonist 14, 350, 353, kininase activity 473 354,357 Cardiovascular reflex pain and 591 Carrageenin Cadmium salts anti-inflammatory effect 536 intoxication, vascular permeability and 41 Bk release 487--490 Calcium cl inhibition 536 histamine release and 349,363 chronic inflammation and 275, 276 leucocyte adhesion and 49 complement activator 235 lysosomal enzyme release and 269 complement depletion 536 lysozyme release from PMN 298 counter-irritant 532, 534, 536 platelet aggregation, co-factor in 144, 145, delayed-prolonged leakage and 46,47 155, 156, 161 experimental arthritis 487 platelet dense body and 141,145,167 hyperalgesia and 602 platelet shape change and 144 kininogen depletion 467, 487 release in platelet release reaction 145 lysosomal enzyme release 275, 276 SRS-A release and 363 macrophage, effect on 275,276 storage pool disease and 167 pain threshold and 480 Calcium acetylsalicylate platelet aggregation potentiation 181 Bk-induced bronchoconstriction and 501 Carrageenin inflammation, see carrageenin Bk-induced pain and 481 oedema Calcium ionophore A23, 187 Carrageenin oedema mediator release and 351, 363 adrenaline and 555 SRS-A synthesis/secretion 363 anti-inflammatory drug assay 487 Capillary Bk and 487--489 blood flow in 27-29 complement activation and 528, 529 delayed prolonged leakage of 41,42,46 histamine and 488, 489, 527 direct vascular injury and 45-48 5-HT and 488,489,527,528 fenestrated 31-34,42 formation in scar tissue 210, 212, 213 inhibition by counter-irritation 527, 528 gap formation in 34-39 inhibition by hexadimethrine bromide 489 histamine-type permeability factor and 324, inhibition by indomethacin 181, 487, 488 38,45,46 inhibition by kininogen depletion 488, 489 inflammatory exudate resorption 56 inhibition by SBTI 487, 488, 576 kinin and 488,489,527, 576 in normal microcirculation 27 platelet and 181 leakage 34-48 leucocyte migration and 51 potentiation by BPP9a 488 lymphatic 57 PGE1 and 489, 527 permeability 33, 34 sequential release of mediators in 578 pore in 33, 34 Carrier specificity 237,238 sinusoid 33, 58 Cartilage structure 27, 30-33 autolytic degradation 283-285 Capillary labelling cell proliferation control 209 leakage and 42-46 healing 225,226 leucocyte migration and 54, 55 hyaluronic acid and 209 lymphokine and 327 Casein Carboxypeptidase A chemotactic effect 117, 120, 122, 128, 129 Arthus reaction and 301 leucocyte adhesion and 112 hydrolysis of Bk and kallidin 300 Catalase lysosomal acid cathepsin 299 platelet aggregation inhibition 156 742 SUbject Index

Catecholamine skin reaction and 231 anti-inflammatory effect 555 transfer of 237-239, 249 inflammatory mediator 12 tuberculin reaction and 237, 257, 258 kininogen level and 469, 496, 497 Cell membrane, see also basement membrane; Cathepsin A lipid bilayer in platelet IX granule 272 chemoattractant and 121, 122, 124, 126 lysosomal enzyme 299 cyclic nucleotide and 306 Cathepsin Bl cyclo-oxygenase activity and 382 Arthus reaction and 301 fusion, complement and 271 kinin formation and 300 fusion, lysosomal enzyme release and 268 lysosomal enzyme 299 hydrophobicity and 122 tissue repair and 301 leucocyte locomotion and 115, 122, 124, Cathepsin C 125 blood clotting and 301 lysis by cytotoxic particles 272 inflammatory mediator and 301 lysis, lysosomal enzyme release and 267 lysosomal enzyme 299 protein 122, 124 Cathepsin D Cell proliferation, see also specific cell types assay 300 blood supply and 213 degradation of cartilage 283, 300 kinin and 497 degradation of proteoglycan 285, 300 tissue regeneration and 206-208 inflammatory reaction and 300 Cellular immunity, see cell-mediated kinin generation 286, 300 immunity serum protein digestion 300 Cellulose-sulphate Cathepsin E Bk-release 487 kinin formation and 300 kininogen depletion 467, 488 lysosomal enzyme 299 oedema formation 489 Cathepsin F Central nervous system (CNS) cartilage and 300 repair 226 Cationic protein inflammatory modulator 557 anti-bacterial 186, 187 pyrogen entry 621, 622 in PMN granule 302 Cerebral ventricle platelet IX-granule 186, 189 fever production and 620-622 pro-inflammatory effect 302, 303 Cerebrospinal fluid (CSF) release by endotoxin 186, 187 PGE content 637---649 Cell-cell adhesion 109-111 pyrogen entry 622 Cell-mediated (Type IV) hypersensitivity, see Chalone delayed hypersensitivity cell proliferation and 207,208 Cell-mediated immunity inflammatory modulator 544, 556 allergic arthritis and 232, 239, 255, 259 Chemical injury antigen recognition in 237 kinin release and 487--491 carrier specificity in 237,238 resolution and 56 chemical contact sensitivity and 239, 247 vascular permeability and 43 delayed hypersensitivity and 232,237, 247, Chemical mediator, see endogenous mediator 314--317 Chemoattractant, see also chemotactic factor graft rejection and 239 classification 118-120 granuloma formation and 232, 237, 239, mode of action 121-124 251 Chemokinesis histamine and 357-360 chemotaxis and 116, 117 homeostasis in 249,250 definition 115 lymphokine and 239,252,331,334 in vivo 129 macrophage activation and 77, 251, 324, lymphocyte response 128 325 Chemoreceptor macrophage migration inhibition and 317, pain 591,592,594 326 Chemotactic factor mechanism 237-239,247 bacterial 120 mediator participation in 315-317 cellular 119 pleural cavity and 257, 258 complement component 118, 234, 440--442 Subject Index 743

cytophilic antibody 119 chronic delayed hypersensitivity and 232 cytotaxigen 118, 119 collagenase from macrophage and 280 cytotaxin 118, 119 complement alternative pathway and 279 from platelet 173-176 counter-irritation and 529, 530, 535 humoral 119, 120 defective lymphocyte reactivity to PGE and identification 116 336,554 kallikrein 119 endogenous antigen and 252, 253 leucocyte adhesion and 55 granuloma formation 251 leucocyte locomotion and 116-129 homeostasis and 525, 526 lipid 120 hydrolytic enzyme release and 267, 272, lymphokine 118, 119,328-330 273,277 mode of action 121-124 immune complex and 232 N-formyl-methionyl peptide 122 immune complex, acid hydrolase release and protein 120 277 specificity 126, 127 leucocyte migration and 61,62 Chemotaxis (leucocyte) lymphokine and 336 by arachidonic acid metabolite 375 macrophage and 272, 273, 530 by PG 374, 375 macrophage, hydrolalase release and 277 complement and 118,234,440--442 macrophage proliferation and 92 definition 115 mononuclear phagocyte and 87, 97, 98 Hageman factor and 472 non-immunological, hydrolase release and in vivo 128, 129 273-277 leucocyte adhesion and 55 platelet and 189 leucocyte migration and 55 vascular event 571,572 lymphokine and 118,119,328-330 Chymotrypsin measurement of 116,117 anti-enzyme and 346 membrane-active enzyme and 123 counter-irritant 558 motor mechanism of 124, 125 inhibition byaprotinin 470 ofleucocyte cell types 126-128 kinin release 471 protein/DNA synthesis and 126 kininase activity 473, 474, 495, 503 Chlorimiprazine thermic oedema and 484 PG hyperthermia and 634 Cimetidine p-Chlorophenyl-alanine (p CPA) histamine-type 2 antagonist 14, 350, fever, effect on 633 353-355 Chloroquine Cinanserin leucocyte locomotion and 126 PG hyperthermia and 634 rheumatoid arthritis and 412 Cinnarizine Chlorpromazine complement inhibitor 448 anti-cyclo-oxygenase activity 411 Cirrhosis 211 PG hyperthermia and 634 Cisterna magna Cholera enterotoxin fever production and 620 histamine release inhibition 350 Clonidine MIF and 358 histamine-type 2 agonist 354 Cholinoceptor Clostridium perfringens IX toxin mediator release and 350, 363 vascular permeability and 43,45,46 Chondroitin sulphate Clostripain Hageman factor activation 471 kinin release 471 in connective tissue 215 Clotting factor, see also calcium; fibrinogen; inhibition by hyaluronic acid 209 Hageman factor; PF3; PF4; prothrombin in hypertrophic scar 224 I 139 Chondromucoprotein V 139 scar tissue and 208 VII 139 Chronic inflammation, see also inflammation; VIII 139, 163, 165 inflammatory reaction IX 139 acute inflammation, inhibition and 579 X 139 carrageenin induced 275 XI 61,139 cell-mediated immunity and 237 XII 61,139 744 Subject Index

Clotting factor, Type II 217, 218 blood clotting mechanism and 162 Type III 217,218 plasmin activation and 61 Type IV 217, 218, 221 platelet coat and 139 Collagenase ristocetin and 163 acute inflammation and 280 Von Willebrand's disease and 165 Clq haemolytic function and 426 Coagulation, see blood clotting chronic inflammation and 280 Cobra venom factor collagen degradation 280,302 Arthus reaction and 241,242,257 inhibition by cysteine 302 Bk formation 16 inhibition by EDTA 179,280,302 C3 inactivation 235 inhibition by OC z macroglobulin 281 complement activator 447 inhibition by serum 179, 280, 302 complement depletion 236,241,257 in platelet oc-granule 179 complement phylogeny and 437 in PMN specific granule 302 Shwartzman reaction and 236,246, 247 oedema formation, inhibition 482 Codeine secretion by fibroblast 281 platelet PG biosynthesis and 153 secretion by macrophage 76, 77, 280, 281 Co-factor secretion, inhibition by dexamethasone 287 in PG biosynthesis 394-396 secretion, inhibition by hydrocortisone 287 in platelet aggregation 144, 145 synthesis, induced by lipopolysaccharide Colchicine 280. analgesic effect 608 synthesis, inhibition by cycloheximide 280, antimitotic agent 220 281 collagen formation and 220 tissue injury and 76, 302 fibroblast adhesion and 111 Collagen fibre histamine release inhibition 349 connective tissue formation and 216 leucocyte locomotion and 124 scar tissue formation and 208,211 lysosomal enzyme release inhibition 287, Colony-stimulating factor 76, 77, 93 303, 304 Complement microtubule disaggregation 111, 124, 140, 233-237,425--449 220,304,349 abnormality, acquired 425, 445--447 neutrophil degranulation 304 abnormality, genetic 233,235,241,242 Collagen activator 447 amino acid composition 216,217 allergic vasculitis and 242 basement membrane and 212, 217 Arthus reaction and 233,235,241,242,257, blood vessel wall and 217 443,444 bone healing and 225 biological activity 439--443 cartilage and 217 cartilage degradation and 282-285 chemoattractant 120 chemotactic factor 117, 118, 233, 234, 440, connective tissue formation and 214, 215 441 Dupuytren's Contracture and 224 counter-irritation and 530, 536 export 220,221 cytolysis 283, 434, 435 Hageman factor activation 471 cytolytic (Type II) hypersensitivity and lysosomal protease and 179,482 283-285 placenta and 217 deficiency 444 platelet adhesion and 142, 144 experimental tissue injury and 443, 444 platelet aggregation and 140,141, 145, 146, human disease and 242,244,444--447 153,156,159-161,179,188 immune adherence and 233,234,441--443 platelet collagenase and 179 immune complex disease and 243, 244 scar contraction and 222,223 immune haemolysis 233, 434, 435 scar formation and 208,211,212 immunological inflammatory reaction and segment long-spacing 218 239-247 skin and 217 inhibition by IT AIF 542 structure 216-218 inhibitor, synthetic 447--449 synthesis 211,212,214,215,218-220,222 leucocyte mobilizing factor 441 synthesis, inhibition by PG 554 lysosomal enzyme release from connective Type 1 217, 218 tissue cell 282-285 Subject Index 745

lysosomal enzyme release from macrophage Cl, rheumatoid arthritis and 446 and 279,280 Cl species compatibility 437 lysosomal enzyme release from PMN 270, Cl synthetic inhibitor 448, 449 271 clINH 426, 436 opsonisation 233, 283 clINH deficiency 439, 444, 445, 449 permeability factor 439, 440 Clq 425,426 phylogeny 436---439 Clq deficiency 444 platelet aggregation and 161, 184,233,234 Clq Ig binding inhibition 449 polyarteritis nodosa and 242 Clq, rheumatoid arthritis and 446 reaction, activation pathways 425----431 Clq synthetic inhibitor 448 reaction, amplification pathway 425,431 Clq, SLE and 446 reaction, control of 436 Clr 425,426 reaction, effector pathway 425, 433----436 Clr deficiency 42/i, 444 reactive lysis 434 Clr inhibition by CIINH 426, 436 receptor 73,441,442 Clr synthetic inhibitor 448, 449 serum sickness and 243 CIs 425----428 species compatibility 437----439 CIs deficiency 42C2, 444 urate oedema and 490,491 CIs inhibition by CIINH 426, 436 Complement alternative activating pathway CIs synthetic inhibitor 448, 449 235,236,428----433 C2 426---428 abnormality, acquired 445 C2, C4b binding inhibitor 448,449 activation 432, 433 C2 cleavage, inhibition by CIINH 436 amplification pathway 431 C2 deficiency 428, 444 component 235,428,429 C2, HAE and 439, 445 immunological inflammatory reaction and C2, rheumatoid arthritis and 446 245-247 C2, species compatibility 437 inhibitor 430, 432 C2a 427,428,431 lysosomal enzyme release and 279, 280 C2b 427 Shwartzman reaction and 232,236,237, C2i 428 245-247 C3 233,235,428----433 Complement classical activating pathway C3, antigenic 429 233-235,425----428 C3, Arthus reaction and 241,443 activation by immune complex 233, 235, C3 chemotactic activity 234, 440 425 C3, chronic glomerulonephritis and 446, arthritis and 244 447 Arthus reaction and 234, 235, 239-242, C3, CVF and 235, 437 443,444 C3 deficiency 444, 445 components 233, 425----428 C3 degradation by lysosomal enzyme 301 component deficiency 444 C3, infection and 244,444,445 dengue haemorrhagic fever and 244, 245 C3 leucocyte mobilizing factor 441, 530 glomerulonephritis and 244 C3 lymphocyte activation 119 immune adherence 233, 234 C3 lymphocyte receptor 442 immune complex disease and 244 C3, lysosomal enzyme release and 271,301 immune complex reaction and 231, 233, 243 C3, rheumatoid arthritis and 446 immunological inflammatory reaction and C3, serum sickness and 243, 444 239-245 C3, Shwartzman reaction and 236,237,246 rheumatoid arthritis and 446 C3 synthetic inhibitor 449 serum sickness and 243, 244 C3, SLE and 446 SLE and 244, 446 C3a 428,433, 435, 436 Complement component C3a, acid hydrolase release and 271, 279 anaphylatoxin inhibitor (AI) 436, 440 C3a anaphylatoxic activity 233, 234, 351, fJ 1 H 430----433, 436 440 Cl 235, 425----428 C3a chemotactic activity 234, 440 Cl degradation by lysosomal enzyme 301 C3b 429----433,436 CI esterase activity, HAE and 439 C3b fluid phase 430,431 Cl esterase inhibitor, kallikrein inhibition C3b immune adherence 233,430,433, 470 441----443 746 SUbject Index

Complement component C5a, lysosomal enzyme release and 271, C3b immune adherence, Arthus reaction 301 and 444 C5b 434, 436, 439 C3b immune adherence, lymphocyte C5b synthetic inhibitor 448 stimulation 442 C5b67 433-435 C3b immune adherence, lysosomal enzyme C5b67, activation and 447 release and 271, 279, 280, 442 C5b67 chemotactic activity 233, 234, 440, C3b, phagocytosis and 233,441,442 443,446 C3b species compatibility 438 C5b67, lysosomal enzyme release and 271 C3b surface bound 430,434 C5b67 synthetic inhibitor 448, 449 C3b surface bound, activation and 432 C5i 434 C3b surface bound, haemolysis and 433 C6-+C9 233, 434, 435 C3b surface bound, synthetic inhibitor 448 C6-+C9 deficiency 434, 445 C3b synthetic inhibitor 449 C6-+C9, species compatibility 439 C3bBb convertase 429-432,436 C6-+C9 synthetic inhibitor 448 C3bBb convertase neutrophil deactivation i) 429,431-433,437 441 i), species compatibility 438 C3bBb convertase species compatibility i) synthetic inhibitor 448 438 Factor A 428 C3b inactivator (C3bINA) 430,432,436 Factor B 235,429,431-433,437 C3b inactivator deficiency 444,445 Factor B species compatibility 438 C3b inactivator, immune adherence and properdin (P) 235, 428-433 441,442 properdin (P), species compatibility 438 C3b inactivator inhibition 447 Complement sufficient anti-serum C3c 430,431 lysosomal enzyme secretion and 282-285, C3 convertase, alternative 428-430 286 C3 convertase, classical 428, 431, 437, 441 Compound 48/80 C3d 430, 441, 442 counter-irritant 552, 536 C3 nephritic factor (C3NeF) 430,431,447 mediator release 351 C4 427,428 Concanavalin A (Con A) C4, Arthus reaction and 443 lymphocyte transformation and 322 C4, cleavage by C3bINA 430 mediator release and 351 C4 deficiency 444 Connective tissue C4, RAE and 439, 440, 445 cells of 213-215 C4 phylogeny 437 degradation by lysosomal enzyme 285,286 C4, rheumatoid arthritis and 446 fibrous component 216-222 C4, Shwartzman reaction and 246 formation 213-222 C4 synthetic inhibitor 448 lysosomal enzyme secretion 282-285 C4, SLE and 427,446 non-fibrous component 215, 216 C4b 427,428 scar formation and 208, 209 C4b immune adherence 441 Contact inhibition (of movement) C4b2A convertase 427,428,431,433,436 leucocyte locomotion and 114, 115 C4c 430 scar formation and 208, 209 C4d 430 Corticosteroid C4i 427,428 analgesic action 608 C5 233,428,433-435 anti-phospholipase activity 412 C5, Arthus reaction and 443, 444 counter-irritation and 540 C5 convertase 427,433, 434 leucocyte locomotion and 126 C5 deficiency 433, 445 mechanism of action 412 C5 degradation by lysosomal enzyme 301 Cortisol, see hydrocortisone C5, lysosomal enzyme release and 271 Counter-irritation C5 synthetic inhibitors 448,449 acute inflammation suppression 527-529 C5a 345,434,436 analgesic action 526,527,531,532,534,541 C5a anaphylatoxic activity 233, 234, 351, anti-inflammatory action 528, 532 436 534-541,558 C5a chemotactic activity 233,234,440, anti-inflammatory humoral factor and 441,446 536-541,559 Subject Index 747

chronic inflammation suppression 529 PG fever and 635, 636 competitive exhaustion 530, 533, 535, 536 reciprocal relationship with cGMP 305, complement activation inhibition 530 306 complement exhaustion 530, 536 second messenger 349 IT AIF 536---541 SRS-A release inhibition 305, 363 leucocyte migration inhibition 530 tuberculin reaction and 258 mechanism 535--541 Cyclic AMP, see cyclic adenosine 3',5'-mono• mediator inhibition 530 phosphate modulation of inflammation 526, 535, 536 Cyclic GMP, see cyclic guanosine 3',5'-mono• oedema, suppression 527-529 phosphate stimulus, chemical 532, 533 Cyclic guanosine 3',5'monophosphate stimulus, non-chemical 533 (cGMP) stimulus, site of 534 antibody-dependent cellular cytotoxicity vascular effect 530, 531, 533 and 305 Crushing injury elevation by cholinergic stimulation 305, vascular permeability and 42, 43 350, 556 Cu-chlorophyllin elevation by PHA 306, 322 complement inhibitor 449 histamine release and 305, 350 HI receptor activation 354 Cutaneous anaphylaxis 231 leucocyte locomotion and 125 Cutaneous basophil hypersensitivity (CBH) lymphocyte cytotoxicity and 306 248, 359 lymphocyte transformation and 322 CVF, see cobra venom factor lysosomal enzyme release and 304--306, Cyanogen bromide 218 556 Cyclic adenosine 3',5' -monophosphate mediation of inflammation and 553 (cAMP) mediator release and 350 analgesia and 608 microtubule and 306 antibody-dependent cellular cytotoxicity pro-inflammatory involvement 556 and 305 reciprocal relationship with cAMP 305, anti-inflammatory involvement 554, 556 306 Arthus reaction and 257 SRS-A release and 305, 350 assay, in vivo 259 Cyclic nucleotide, see also cAMP, cGMP DNA synthesis stimulation 322 anti-inflammatory effect of adrenaline and elevation by adrenaline 556 556 elevation by f3-adrenoceptor stimulation anti-inflammatory effect of PG and 554 350, 556 calcium effect 305 elevation by cholera enterotoxin 350, 358 cell function regulation 125,305-307 elevation by histamine 350, 354--356 leucocyte migration and 125, 126 elevation by PG 150, 322, 350, 553, 554, lymphocyte transformation and 322 608,635 lysosomal enzyme release and 304 elevation by theophylline 350, 554, 635 macrophage activation and 324 elevation by zymosan 305 mediator release modulation 349 histamine release inhibition 305, 350, 363 microtubule and 304 H2 receptor activation and 354,355, 553 Cycloheximide modulatory feedback leucocyte locomotion and 125 mechanism 554 lymphocyte cytotoxicity and 306 collagenase production inhibition 281 lymphocyte transformation inhibition 306, lysozyme secretion inhibition 282 322 Cyclohexylbutylphosphonofluoridate lymphocytotoxin release inhibition 305 complement inhibitor 448 lysosomal enzyme retention 303--306,553 Cyclo-oxygenase macrophage migration and 324 activating factor generation 392 microtubule disaggregation 304, 306 biochemical data 398, 399 modulation of inflammation and 350, 553, characterisation 382, 383 554,556,560 chemiluminescence and 401,402 pain production 608 co-factor requirement 394--396 phagocytosis inhibition 304 co-oxygenation 401,402 platelet aggregation and 150, 152, 155, 161 cyclic endoperoxide generation 384--387 platelet shape change and 144 deficiency 171, 172 748 Subject Index

Cyclo-oxygenase basophil and 249, 250 distribution 383, 384 carrier specificity 237,238 enzymology 394-402 cell-mediated immunity and 232, essential fatty acid substrate 377-382,384 237-239,247,314,315,326,336,345 HHT generation 387, 388 criteria for 314,315 inhibition by aspirin-like drug 171, 374, cyclophosphamide effect 249, 250 383,387,391,394,400 erythema 237, 326 location 382 histamine and 356, 360 non-prostaglandin product 375, 390--394 histology 315 optimal activity 396-400 history 231,314 PG generation 388-390,394-400,402 homeostasis 249, 250 purification 394 5-HT and 361 regulation by phospholipase A2 380--382 induration 237,248, 326 substrate specificity 379 lones-Mote reaction and 248,249,314, thromboxane generation 390--393 315 turnover/replacement 400,401 kinetics 247,248 Cyclophosphamide (CY) lymphocyte activation and 238, 315-318 delayed hypersensitivity and 249, 250 lymphocyte migration and 51 Cyproheptadine lymphokine mediation of 239, 314-318, 5-HT antagonist 361 326--328,331,334,336 PG hyperthermia and 634 lysosomal enzyme release 279 Cysteine monocyte accumulation 328 in collagen 218 skin reaction 231, 232, 247, 248, 314, 326 Cytochalasin B suppressor cell and 249, 250 collagen secretion and 281 tissue damage mechanism 279 collagen synthesis and 220,221 T-Iymphocyte and 238,279 lysosomal enzyme release and 268, 270, 271 transfer 237,249,314 microfilament function and 220, 269 tuberculin type 248, 249 phagocytosis inhibition 268-270 Delayed-prolonged leakage 41,42,46,47 Cytochrome P 450 Delirium PG biosynthesis and 402 in fever 644 Cytolysis Dental plaque by complement 435 macrophage and 274, 275 lysosomal enzyme release and 267 Dermatan sulphate of antibody-coated target cell 305 in hypertrophic scar 224 Cytophilic antibody in proteoglycan of connective tissue 215 chemotactic effect 119, 121 Desmosine Cytotoxic agent in elastin 222 cytoplasmic enzyme release 267 Dexamethasone inhaled 276 collagenase secretion inhibition 287 lysosomal enzyme release 267, 277 lysosomal enzym release inhibition 286, mediator release and 576 287 membrane rupture 267 macrophage, effect on 287 pneumoconioses and 276 monocyte, effect on 88 specificity 576 plasminogen activator secretion inhibition Cytotoxic (Type II) hypersensitivity 345 287 Cytotoxicity Dextran of asbestos 276, 277 anaphylactic syndrome 579 of mononuclear phagocyte 77 Bk release 487 of silica 276, 277 counter-irritant 532 hexadimethrine bromide and 489 Dehydromonocrotaline (DHM) hyperalgesia 602 capillary labelling and 42 kininogen depletion 467, 485 delayed-prolonged leakage and 46 local Shwartzman reaction and 236 Delayed hypersensitivity thermic oedema and 485 antigen recognition in 237 Dextran oedema Arthus reaction and 248 hyperalgesia 602, 605 Subject Index 749

pain threshold and 480 enzyme-induced oedema and 482 suppression by anti-histamine agent 489, in pancreatic extract 222 490 in platelet a-granule 179, 272 suppression by counter-irritation 528 in PMN lysosome 286, 301 suppression by decerebration 557 lesion healing and 76 suppression by hexadimethrine bromide synthesis/secretion by macrophage 76, 77, 489 281 suppression by 5-HT antagonist 489, 490 vascular subendothelium degradation 179, suppression by kininogen depletion 488 301 Dextran sulphate Elastic fibre, see also elastin complement inhibitor 448, 449 in collagenous structure 221 Diabetes in connective tissue 214 platelet aggregation in 159 scar tissue and 222 Diapedesis, see also leucocyte migration synthesis by fibroblast 214,222 discovery 9, 10 Elastin Dihomo-y-linolenic acid elastase and 222, 286 biosynthesis 379 Hageman factor activation 471 cyclo-oxygenase substrate 377,380, in connective tissue 221 382--384,387,393,394 structure 222 HHT generation 387 E1ectrocortical sleep

nomenclature 377 produced by PGE j 628,629 platelet aggregation, reversal 145 Ellagic acid PGE j generation 384 carrageenin oedema inhibition 489 8-iso-PGE j generation 393 Hageman factor activation 471 PGEz generation 384 kininogen depletion 467, 488, 489 PGH j generation 383 Endocapillary layer 13,14-dihydro-15-keto PGE leucocyte adherence and 49 biological activity 409,410 Endocytosis, see also pinocytosis; phagocytosis half life 408 73, 76 in PG catabolism 406,407 Endogenous antigen 13,14-dihydro-PGE j adjuvant arthritis and 253 biological activity 409,410 allergic arthritis in rabbit and 255 Diisopropylphosphofluoridate (DFP) inflammatory response and 252,253 complement inhibitor 429,448 rheumatoid arthritis and 253 Diphenhydramine hydrochlorid (Benadryl) Endogenous pyrogen, see also leucocyte histamine theory and 14 pyrogen Dipyrone antipyretic and 621,640,641,648 analgesic effect 607 blood brain-barrier and 622, 646 Direct vascular injury characterisation 619 delayed-prolonged leakage and 46, 47 CNS injection 620, 621 mechanism 47,48 endotoxin fever intermediary 618,619, vascular permeability and 45--48 622,640 Dupuytren's contracture 211,224 exogenous pyrogen and 618 fever production 617, 620--622, 646, 647 Egg albumin in CSF 622 kininogen depletion 467 induced by endotoxin 619,646 Ehlers-Danlos syndrome 220 induced by inflammation 619 5,8,11,14,17-eicosapentaenoic acid induced by tissue injury 619 PGE3 generation 384 intravenous injection 620--622 5,8,11,14-eicosatetraynoic acid (TYA) nomenclature 617 platelet aggregation inhibition 141, 158, PG synthesis stimulation 640, 648, 649 159 PGE in CSF and 640,641,648 Elastase pre-optic anterior hypothalamus and cartilage proteoglycan degradation 179, 620--622,646 286 release from Kupffer cell 619 connective tissue degradation 179, 286 release from leucocyte 618,619,646 elastin degradation 222, 286 release from microglia 647 750 Subject Index

Endogenous pyrogen vascular labelling and 34, 36, 38, 39, 42, 43, release from monocyte 619 583 release from neutrophil 618,619 venular localisation 38 release from reticulo-endothelial system Endothelium, see endothelial cell 619,647 Endotoxin Endopeptidase anti-bacterial protein release and 186, 187 lysosomal enzyme 299 blood-brain barrier and 621,646 Endoperoxide, see prostaglandin endo• blood clotting and 185, 186 peroxide and specific endoperoxides blood clotting and, inhibition by heparin Endoperoxide-PGD/PGE isomerases 185, 186 deficiency 390 catalepsy and 644 drug action on 415 cerebral ventrical injection 620, 624, 626, PGD formation 388 638,639,647 PGF formation and 390 characterisation 618 complement alternative pathway activation Endoplasmic reticulum (ER) 235,237,245,432,447 collagen synthesis and 218,220 focal infection activation 642 in epitheloid cell 69 haemorrhagic necrosis and 185, 236, 245, in mononuclear phagocyte, peroxidase 246 activity and 72, 73 hypotension and 185 Endothelial cell intravenous injection 185, 232, 236, 245, active transport and 34 618,624,626,638,639,641,647,649 actomyosin in 36, 38, 47 kneet joint inflammation and 186 acute inflammation and 38--42, 48, 49 local inflammation and 185,236,245 basement membrane synthesis 211 platelet aggregation and 139, 184-186, damage 41,42,486 236 delayed-prolonged leakage and 47, 48 platelet aggregation, inhibition by indo• direct vascular injury and 41--43, 45--48 methacin 185 histamine effect 354 platelet IX-granule and 186, 187 intercellular junction 30, 31, 34-36, 47, pre-optic hypothalamic region and 617, 48,51 620,624,625,637,640 leucocyte adhesion made 49, 51, 109, 111, PG synthesis stimulation 638,640,644,647 112,474, 571 Shwartzman reaction and 185-186, 232, leucocyte migration and 51-54,571 236,237,245--247 lymphatic 57, 58 temperature sensitive neurone and 629, lymphocyte adhesion and 51, 112 630 lymphocyte migration and 51 tolerance 245, 619, 621 metabolism in injury 48 Endotoxin fever passive transport and 33 antipyretic and 617,621,630,648 platelet adhesion and 51, 142 aspirin and 638 pore system and 34 Db-cAMP and 637 PGI2 generation 142 endogenous pyrogen and 618,619,640,646 scar formation and 210,211 indomethacin and 638,647 separation 47,48 mediation by PGE 617, 637, 647 shape change 48 paracetamol and 638 structure 30-33 pentobarbitone sodium anaesthesia and Endothelial gap formation 642 acute inflammation and 39--42, 59, 583 production 618,620,624-626 increased permeability and 34, 36, 38, 39, PGE in CSF and 637-639, 641, 642, 644, 41,47,583 648,649 induced by bradykinin 36 Endotoxin shock induced by histamine 34, 36, 574, 583 anti-bacterial cationic protein and 186, 189 induced by 5-HT 36,583 complement alternative pathway and 245 insulin and 551,552 platelet IX-granule and 186, 189 lymphatic 57,59 PG level in 412 mechanism 36, 38 Eosinophil molecular sieving and 54 adhesion 51 Subject Index 751

C3a/C5a effect 440 Exogenous pyrogen, see also bacterial pyrogen; C3b receptor 441 endotoxin chemotaxis 127,357,440 blood brain barrier and 621,622 histamine effect 127,357 cerebral ventricle injection 620 migration 51, 127, 357 fever production 618,620 Eosinophil chemotactic factor of anaphylaxis fever production, endogenous pyrogen and (ECF-A) 618 kinetics of release 350 fever production latency 620 pre-formed 351 fever production, PG in CSF and 637 release from basophil 127, 345, 348, 351 intravenous injection 620 release from mast cell 127,345,348,351 nomenclature 617 release from neutrophil 127,345,363 pre-optic anterior hypothalamus injection release induced by anaphylatic reaction 620 127, 348 Exopeptidase release induced by phagocytosis 363 lysosomal enzyme 299 Epitheloid cell Experimental arthritis in granuloma 87,251,252 allergic 253-256 nomenclature 69 carrageenin-induced 487 structure 69 cell-mediated immunity and 255 Epsilon aminocaproic acid (EACA) chronicity 254--256 complement activator 447 FCA induced 253, 254 complement inhibitor 449 in guinea pig 254 Ergamine, see histamine in rabbit 254, 255 Erythema in rat 253, 254 arachidonic acid metabolite and 375 in swine 256 Arthus reaction and 234, 240 mono-articular 254, 255 blood flow and 326, 327 mycoplasma and 256 Bk and 17 ovalbumin induced 254 C3a and 234 Experimental inflammation, see inflammatory delayed hypersensitivity and 234, 236, 247, model 248 Exudate, see inflammatory exudate H-colloid and 13 histamine and 13, 234 lymphokine and 326, 327 Factor increasing monocytopoiesis (FIM) measurement 247,327 inflammatory reaction and 93-96 Shwartzman reaction and 245 kinetics 93 Erythema nodosum leprosum 242 mode of action 94,95 Erythrocyte site of production 94 C3b receptor 441 Fatty acid kinase in 473 p and w oxidation 406 migration 51 cyclo-oxygenase substrate 377 precursor 207 esters 377 thrombus formation and 147 Jipoxygenase substrate 404 Erythropoietin nomenclature 376, 377 anoxia and 207 PG generation 382 Escherichia coli reaction rate 377,378 endotoxin 621 Fatty acid hydroperoxide suppuration and 62 pain production and 601 Essential fatty acid FCA, see Freund's adjuvant conversion to PG 384 Fenestra, see under capillary cyclo-oxygenase substrate 377 Fever, see endotoxin fever, PG fever, pyrogen deficiency 159, 172 fever Ethylenediaminetetraacetic acid (EDT A) Fever, non-specific 620, 632, 635, 636, 642, leucocyte adhesion and 49, 112 643 plasma kininase inhibition 473 FIA, see Freund's adjuvant platelet shape change and 144, 150 C fibre platelet aggregation and 150 pain transmission 591,592 752 Subject Index

b fibre Foetal ex-2-globulin pain transmission 591 inflammatory modulator 546,548,551 Fibrin Formoloedema haemostasis and 164 suppression by counter-irritation 528 resolution and 61 Freund's adjuvant scar tissue formation and 209~211, 212, allergic arthritis and 253~255 213 Arthus reaction and 240 Fibrinogen, see also clotting factor delayed hypersensitivity and 247~250 haemostasis and 164, 165 lones-Mote reaction and 248 platelet aggregation and 145, 152, 155, 161 tuberculin reaction and 247~249, 258 platelet coat and 139 F-substance 470 Fibrinolysin 61 Fumaropimaric acid Fibrinolysis complement inhibitor 449 capillary formation and 213 Hageman factor and 472 Gap formation, see endothelial gap formation Fibrinolytic enzyme 61 Gastrin Fibroblast inflammatory modulator 544 adhesion 111, 114 Giant cell capillary formation and 213 nomenclature 69 cartilage repair and 226 granuloma and 87 characteristics 75 Glandular kallikrein CNS repair and 226 kallidin release 465,466,469,474 collagen synthesis 212~214 plasma kallikrein and 469 collagenase secretion 281 Gliosis 226 contact inhibition 114 Glomerulonephritis Dupuytren's contracture and 224 experimental 243 esterase staining 75 clinical 244 mononuclear phagocyte and 74, 75 Glomerulonephritis, chronic, see also MPGN origin 75 complement and 243,446 proteoglycan synthesis 215 Glucocorticosteroid, see also specific drugs receptor 75 collagenase secretion inhibition 287 scar contraction and 223 lymphocyte and 333 scar maturation and 222 lymphoid tissue and 333 scar tissue formation and 208,210,212,213 lymphokine and 333 Fibrocyte lysosomal enzyme secretion and 287 proliferation 213 macrophage and 78, 87, 89, 287 scar formation and 213 monocyte and 81, 87~90 Fibrosis monocytopaenia and 78 drug-induced 225 mononuclear phagocyte and 78, 79, 82, Dupuytren's contracture and 224 87~90 granuloma formation and 252 plasminogen activator secretion inhibition mast cell and 214 287 scar tissue formation and 212 Glucose-I-phosphate systemic sclerosis and 224 proteoglycan synthesis and 215 Ficin fJ-glucuronidase kinin release 471 release from macrophage 274, 275, 278 Filtration coefficient 581,582 release from PMN 304 Flaujeac factor 472 Glutamic acid Fletcher factor, see also prekallikrein 472 in collagen 218 Flufenamic acid Glutathione (reduced) (GSH) Bk-induced bronchoconstriction and 501 co-oxygenation and 401 Fluorescent antibody technique PG biosynthesis and 394-396,399 C3 detection in serum sickness 243 Glutathione peroxidase cartilage autolytic degration and 284 PGE formation and 388, 396 Fluorosulphonyl compound Glycine complement inhibitor 448 in collagen 216, 218 Subject Index 753

Glycoprotein, see also kininogen, 1X-2-glyco- induced by PGEI 375 protein insulin effect 552 cell-cell adhesion and 110 lymphocyte infiltration and 252 leucocyte chemotaxis and 122, 128 mononuclear phagocyte and 87,97-99 lymphocyte adhesion and 112,115 multinucleate giant cell and 87 1X-2-glycoprotein non-toxic 251 inflammatory modulator 545, 547, 548, suppression by counter-irritation 531 559 toxic 251 Glycosominoglycan hypertrophic scar and 223,224 Haemoglobin Glynn arthritis model 254,255 chemotactic activity of 121 Gold sodium thiomalate Haemorrhage complement inhibitor 448, 449 Arthus reaction and 234, 240-242 Golgi vesicles Shwartzman reaction and 236, 245-247 proteoglycan synthesis and 216 Haemorrhagic shock lysosome formation and 297 kininogen depletion and 467 Gonococcal infection Haemostasis suppuration and 62 afibrinogenemia and 165 Goodpasture's syndrome 445 Bernhard Soulier syndrome and 166 Gouty arthritis collagen and 188 kinin and 498, 499 collagenase and 179 Gouty attack cyclo-oxygenase deficiency and 171, 189 urate deposition and 490 defect 138,163-172 Gradient sensing endoperoxide and 189 temporal sensing 117 platelet adhesion and 163 spatial sensing 117, 118 platelet aggregation and 138, 161, 163, 164, Graft rejection 188 cell-mediated immunity and 239 storage pool disease and 167-171, 189 fever production 617 thrombasthenia and 166,167 histamine effect 359 thrombin and 161, 164, 188 leucocyte migration and 51, 188 thrombocytopaenia and 164,165 platelet and 187-189 thromboxane synthetase and 158 Gram-negative bacteria Hageman factor endotoxin 618,236 activation by adrenaline 469 Granulation tissue activation by chondroitin sulphate 471 arthritic serum and 545 activation by collagen 471 counter-irritation and 529 activation by elastin 471 scar contraction and 223 activation by ellagic acid 471 scar tissue formation and 212, 222 activation by HMW kininogen 466 Granulocyte, see also basophil, eosinophil, activation by sodium urate crystals 471, neutrophil 490,491,499 adhesion 112 activation of plasmin 471 kininase in 473,496 blood clotting and 471,472,474 kinin formation/destruction 496 chemotaxis and 472,474 Granuloma formation dependent pathway 472, 474 cell-mediated immunity and 232,237,239, fibrinolysis and 472,474 251 fluid phase activation 471,472 chronic inflamma tion and 87, 232, 237, 251, kinin generation and 471,472,474 252 platelet aggregation and 145 epitheliod cell and 87,251,252 solid phase activation 471,472 fibrosis and 212, 252 thrombin formation and 471 humoral antibody and 232, 251 HI antagonist, see also specific agents 353, immune complex deposition and 232, 251 357, 580 induced by arachidonic acid metabolite lymphokine skin reaction and 328 375 H2 antagonist, see also specific agents 14,354, induced by microbial agent 87,252 357 754 Subject Index

Hapten specificity 237,238 itch and 599 H colloid 13 Lewis triple response and 13,29,475 Headache mechanism of release 349--352 aspirin-like drug and 602 metabolism 353, 403 PO induced 598 oedema formation and 346,480,574 Healing, see tissue repair pain production 481, 593, 598, 599, 601, Heat stroke 608 kinin system and 485 potentiation by PO 173, 578, 583 Heparin pro-inflammatory effect 173, 355, blood clotting inhibition 185 356,360,365 complement inhibition 448, 449 release by C3a 234 in mast cell 214 release by complement 234, 351, 436, 440 kininogen level and 469 smooth muscle effect 13, 353, 355 Hepatic necrosis 207 thermal injury and 484, 486 Hepatocuprein 549 tissue injury and 483 HerEditary angio-oedema (HAE) urate oedema and 490,491 CIINH deficiency in 439,445 vascular permeability and 14,36, treatment 449 353--355,478,486,573,574,583,584 Heterophagic vacuole, see phagolysosome vasodilation effect 574 Hexadimethrine bromide Histamine-type permeability factor, see under Bk release inhibition 475,484,502 permeability factor catecholamine release 493, 502 Histidine decarboxylase 353, 359 kinin release inhibition 489, 493, 502 Histocyte oedema formation inhibition 489, 493, 502 nomenclature 69 tuberculin reaction suppression 493 connective tissue formation and 214 High molecular weight (HMW) kininogen Homeostasis 466,474 defective 526, 560 Hageman factor activation 466,472 of cell-mediated immunity 249, 250 plasma kininogenase and 469 of inflammation 523, 525, 526, 535, 543, Histamine 352-360 546,548 anaphylatoxin and 13, 15, 234, 440 Hormonal control anaphylaxis and 12-14, 17,346-352, connective tissue formation and 215 354,355,360,364 HI receptor 14,353-357 antagonist, specificity 575 histamine mediator function and 553 anti-inflammatory effect 350, 355-360, lymphokine heterogeneity and 333 365,553 H2 receptor 14,353--357 Arthus reaction and 257 histamine modulator function and 350,553 assay 257,352 lymphokine heterogeneity and 333 blood pressure effect 14 on T -lymphocyte 357 C3a and 234,440 Humoural theory 1 cardiac effect 355 Hyaluronic acid carrageenin oedema and 487--489, 578 cartilage and 209 chemotactic effect 127, 356, 357 chondroitin sulphate synthesis inhibition counter-irritant 532 209 delayed hypersensitivity and 360, 365 collagen synthesis inhibition 209 endothelial gap formation and 36, 38, 574, connective tissue cell control 209, 224 583,584 hypertrophic scar and 224 gastric effect 355 proteoglycan synthesis inhibition 209 histamine theory 12-15 Hydraulic conductance 581, 582 immune complex deposition and 360, 365 Hydrocortisone in 1j>asophil 348, 352 anti-inflammatory effect 550 infection and 492 graft rejection and 188 inflammatory mediator 12-15,17,374, kinin release inhibition 502 475 lysosomal enzyme release inhibition 286, inhibition by counter-irritation 530 482 in mast cell 214,347,348, 573, 575 mononuclear phagocyte and 79, 81, 82, 86, in platelet 348 88-90,287 Subject Index 755

Hydrolase see acid hydrolase Bk -potentiation 17, 578 Hydrolytic enzyme, see also lysosomal enzyme bronchoconstriction 361 drug effect 286-288 carrageenin oedema and 488, 489, 578 inflammatory mediator generation 286 CNS effect 361 release by phagocytic cell 268-285, counter-irritation and 528, 532 303-307 delayed hypersensitivity and 360, 361 release, mechanism of 267-270 direct aggregating agent 144, 151 release, selective 268-280 drug-induced fibrosis and 225 Hydroperoxide endothelial gap formation and 574, 583 activating factor 392 fever production and 630, 632 arachidonic acid transformation and 385, gastric effect 361 386 histamine release 15,17,578 12L-hydroperoxy-5,8,10,14-eicosatetraenoic hypothermic effect 627 immune complex deposition and 360, 361 acid (HPETE) generation 385,404 in basophil 214, 348 inflammatory mediator 15, 17,361,374, pro-inflammatory effect 375 475,573 15-hydroperoxy PGE 388, 390 in mast cell 214, 348, 360, 573 15-hydroperoxy PG-R2, see prostaglandin in platelet 173, 348, 360, 361 endoperoxide G2 metabolism 360,361,403 Hydrophobicity pain induction 593 chemotactic recognition and 121 pain receptor sensitization 481, 595, 596, Hydroquinone 606,608 PG biosynthesis and 395 pro-inflammatory effect 360, 361 6-hydroxy-dopamine PG synthesis and 395 fever and 633 receptor 361 Il-hydroxy-5,8,12,14-eicosatetraenoic acid release by C3a: 234,351 393,394 release by immune complex 361 12L-hydroxy-5,8,lO,14-eicosatetraenoic acid release by IgE 361 (HETE) release by PAF 348,361 assay 578 smooth muscle effect 360, 361 generation 385, 388, 404 storage site 360 metabolism 410 thermic oedema and 484 pro-inflammatory effect 375 vascular permeability and 15, 35, 173, 360, 15-hydroxy-5,8,11,13-eicosatetraenoic acid 475,478 393, 394 vasoconstriction 361 15-hydroxy endoperoxide (PGR2), see 5-hydroxytryptamine antagonist prostaglandin endoperoxide H2 eNS effect of 5-HT and 361 12L-hydroxy-5,8,10-heptadecatrienoic acid migraine and 606 (HHT) PG hyperthermia and 634 generation 385,387,388,391 specificity 575 pro-inflammatory effect 374, 375 Hyperaemia Hydroxylysine histamine and 14 elastidin and 222 inflammatory sign lO in collagen 217,218 Hyperalgesia, see also analgesia, pain, pain 8-(I-hydroxy-3-oxopropyl)-9,12L-dihydroxy- receptor 5,10-heptadecadienoic acid (PHD), see aspirin effect 606 thromboxane B2 definition 595 Hydroxyproline inflammatory mediator and 608 in collagen 214,216,218 inflammatory model and 605 in elastin 222 inflammatory process and 588, 595 5-hydroxytryptamine (5-HT) 360-362 migraine and 606 anaphylaxis and 15, 346, 348, 360, 361, paracetamol effect 606 364,579 plasma kinin and 594 Arthus reaction and 257 production by arachidonic acid metabolite assay 257,352 375 blood clotting and 360,361 production by PG 374, 605 - 608 756 Subject Index

Hyperglycemia platelet aggregation and 233, 234, 442, 443 anaphylactoid reaction and 551, 556 Shwartzman reaction and 237 Hypernea rheumatoid arthritis and 446 pseudoefTective response and 589 Immune complex Hyperpyrexia, see fever allergic vasculitis and 242 Hypertensive reflex anaphylactic shock and 183 measurement of pain and analgesia 589, Arthus reaction and 184,242,443,444 590,599 C1 activation 425,446 Hyperthermia, see also fever C 1 activation, inhibition 449 produced by exercise 617 C3b coated, B lymphocyte stimulation and produced by PO 623-637, 645-M7, 649 442 Hypotension C3b coated, immune adherence and 233, Bk-induced 376 441,442,444 Hypotensive kinin, see also specific kinins 464 C3b coated, lysosomal enzyme release and Hypotensive polypeptide, see kinin 442,446 Hypothermia C3b coated, phagocytosis and 441,446 delayed-prolonged leakage and 46 C3b coated, rheumatoid arthritis and 446 produced by cAMP 636 cartilage autolytic degradation and 285 produced by drugs 632 chemotactic activity and 118 produced by endotoxin 624, 626 chronic experimental arthritis and 225 produced by PO 627,629,647 circulating, arthritis and 242,244 circulating, glomerulonephritis and 243, Imidazole 244 thromboxane synthetase inhibition 154 circulating, nephritis and 242, 244 p-imidazolethylamine, see histamine circulating, serum sickness and 444 Immediate (Type I) hypersensitivity, see also circulating, SLE and 445, 446 anaphylaxis complement activation 183, 188, 233-235, Arthus reaction; immune complex 345,346 242 basophil and 347,348 complement activation, autoimmune disease classification 345 and 444,445,494 eosinophil and 345 complement activation, Hageman factor histamine and 346, 354 activation and 495 5-HT and 346,361 complement activation, kinin release and 495 immunoglobulin and 232,314,360 complement activation, rheumatoid arthritis IgE and 346--348,360 and 445,446 IgO and 347,360 complement-dependent function 442 immunological skin reaction 232, 234, 346 dengue haemorrhagic fever and 244 manifestation of 346, 365 deposition, acute inflammation and 271 manifestation of, late 345 deposition, arteritis and 271, 444 mast cell and 346--348 deposition, chronic inflammation and 277 mediator release 346, 348, 364 deposition, glomerulonephritis and 277 mediator release, mechanism of 347, deposition, histamine and 360, 361, 365 349-352,365 deposition, 5-HT and 361 neutrophil and 345, 363 deposition in cartilage 285 platelet and 348 deposition, inhibition by antihistamine SRS-A and 346, 363 agent 243, 360 transfer of 314, 346 deposition, inhibition by 5-HT antagonist vasoactive amine release 345-347,360 243 wheal and flare reaction 346 deposition, nephritis and 271,444 Immune adherence 233,234,441--443 deposition, rheumatoid arthritis and 277, Arthus reaction and 444 285,445 blood clotting and 236, 237, 442 deposition, vascular permeability and 184, B lymphocyte stimulation and 442 243,360 C3 depletion and 237,442 deposition, vasoactive amine and 345, 360 C3bINA and 430 endocytosis by macrophage 277 lysosomal enzyme release and 442, 444 experimental lesion, C3 depletion and 443, phagocytosis and 233,441,442,444 444 Subject Index 757

graft rejection and 187, 188 lysosomal enzyme release 271 granuloma formation and 251 mediator release 346,347 histamine release from platelet and 183 mast cell activation 214,231,346,347 5-HT release from platelet and 361 production, C3 and 442 lymphocyte activation 119 receptor 346, 347 lymphocyte DNA synthesis and 321 SRS-A release 362 lysosomal enzyme release from macrophage Immunoglobulin G (IgG) 277,278 basophil activation 347 lysosomal enzyme release from PMN 234, cartilage autolytic degradation and 270,271 283~287 lysosomal enzyme release, mechanism and chemotactic activity 120 303 complement classical pathway activation lysosomal enzyme release, nephritis and 233 303 immediate hypersensitivity and 347, 360 lysosomal enzyme release, rheumatoid immune complex reaction and 231 arthritis and 303 lysosomal enzyme release and 271 lysosomal enzyme release, soft connective macrophage stimulation 277, 282 tissue cell and 285 mast cell activation 347 lysosomal enzyme release, vasculitis and mediator release 347 303 production, C3 and 442 macrophage stimulation, plasminogen receptor on basophil 347 activator release 282 receptor on mast cell 347 macrophage migration inhibition 317 receptor on mononuclear phagocyte 73 PCA and 182 Immunoglobulin G 1 (IgG 1 ; 1'1 antibody) phagocytosis and 233,441,446 Arthus reaction and 241,443 platelet aggregation and 183, 188 complement alternative pathway activation polyarteritis nodosa and 242, 243 443 receptor, on macrophage 277 immune complex binding and 277 receptor, on monocyte 277 lysosomal enzyme release and 271 rheumatoid arthritis and 277, 285, 303, PCA and 235 445,446 Immunoglobulin G 2 (IgG 2 ; 1'2 antibody) serum sickness and 184, 243, 244 Arthus reaction and 235,241,443 Immune complex disease 244, 245 complement fixation/haemolysis and 235 complement and 345,445 lysosomal enzyme release and 271 histamine and 360 Immunoglobulin G 3 (IgG 3 ; 1'3 antibody) Immune complex mediated (Type III) immune complex binding and 277 hypersensitivity 345 lysosomal enzyme release and 271

Immune haemolysis 233 Immunoglobulin G 4 (IgG 4 ) C3b and 433 lysosomal enzyme release and 271 Complement component phylogeny and Immunoglobulin M (IgM) 437 complement classical pathway activation complement effector sequence and 434,435 233 mechanism of 435 immune complex reaction and 231 Immunoglobulin, see also specific Ig's lysosomal enzyme release 271, 283 Arthus reaction and 242 Immunological reaction Clq binding and 426 cAMP and 350 cartilage autolytic degradation and 283, complement-dependent 233~237 284 histamine and 359, 360 immediate hypersensitivity and 314 inflammation and 231~260 immune complex disease and 243, 244 in skin 231~239 lysosomal enzyme release and 271,283 Imuran, see azathioprine Immunoglobulin A (IgA) Indomethacin lysosomal enzyme release 271 analgesic effect 481,501,606 production, C3 and 442 anti-aggregatoryeffect 153, 156, 185 Immunoglobulin E (IgE) anti-Bk effect 501, 606 anaphylaxis and 231,346-352,360 anti-cyclo-oxygenase activity 182, 383, histamine release 346,347 400,401,411,414 758 Subject Index

Indomethacin Inflammatory mediator antipyretic effect 638, 639, 641, 643 anaphylaxis and 12-15,346---352,364 carrageenin oedema inhibition 181, antagonistic effect 364, 578 487--489 anti-inflammatory effect 365, 553, 554 lymphokine and 336 assay 352, 376---378 lysosomal enzyme release inhibition 287 blocking agent, specificity 580, 584 PG fever and 638,639,641,643 blood flow and 580, 581 PG metabolism inhibition 413 blood pressure and 581 PG synthesis inhibition 153, 577, 646 criteria for 17,475,524,572-576 protein breakdown inhibition 482 filtration and 581,582 Induration half-life 578 delayed hypersensitivity and 237, 248 history 12, 14-17 Shwartzman reaction and 245, 256 hydrolytic enzyme and 286 Infarction hyperalgesia and 597, 608 scar formation and 207 leucocyte migration and 55, 56, 584 Infectious disease oedema and 582 fever and 617 physiological role 365 Inflammation, see also acute inflammation, receptor 580, 584 chronic inflammation, inflammatory release by anaphylatoxin 351,364 response release by antigen 351,363,364 autoimmune phenomena of 252, 253 release by anti-IgE 351,364 auto modulation of, drugs and 558-560 release by calcium ionophore A23187 351, cardinal signs of 1, 2, 6 363 cardinal signs of, Bk and 16, 17,477--482 release by concanavalin A 351 cardinal signs of, histamine and 12-14 release, cAMP and 350 cardinal signs of, 5-HT and 17 release, cGMP and 350 cardinal signs of, inflammatory mediator release from basophil 345, 347-349, 351, and 18 363 cardinal signs of, kinin and 477--482 release from mast cell 345, 346, 348, 349, cardinal signs of, microvascular change and 351 571 release from neutrophil 345, 363 cardinal signs of, pattern reaction and 12 release from platelet 173, 348, 584 cardinal signs of, PG and 374 release, mechanism of 349-352,363--365 cardinal signs of, theories of inflammation release, non-specific 351, 577 and 10,11 release, sequential 578 complement-dependent, alternative pathway synergistic effect 364, 578 245-247 terminology 523, 524 complement-dependent, classical pathway vascular effect, measurement of 574, 239-245 580--584 counter-irritation and 526---541 vascular stasis and 582 definition 1-3,6, 7, 11, 18, 19 vasoconstriction and 580 history 1-3,6---19 vasodilation and 580 homeostatic function 523, 525, 526, 548 Inflammatory model lymphokine and 334-336 anti-inflammatory drug assay and 259, mononuclear phagocyte and 68-99 260,334-336,487,504,505,559,579 specific 12 aspirin-like drug, analgesic assay and 589, specific, histamine and 12-14, 17 590,601,602 theories 10, 12, 13 aspirin-like drug, peripheral mechanism and Inflammatory exudate 590, 602, 603, 605, 606 blood cell in 10 autoimmunity and 252, 253 carrageenin inflammation and 488 counter-irritation and 527-535 inflammatory mediator in 15, 16, 573 histamine and 360,361,527 inflammatory modulator in 523, 543 5-HT and 360,361,527 removal from injured area 56, 57, 59, 60 hyperalgesia and 596,597,602,605 scar formation and 209, 210 immunological 231,232,234,236, suppuration and 61,62 239-252 Subject Index 759

immunological, acute, lysosomal enzyme cAMP and 350 release and 270, 271 cationic protein and 302 immunological, allergic arthritis 232, cell-mediated immunity and 237, 326 253-255 chemical injury and 487 immunological, autoimmunity and collagenase and 280, 302 253-256,529 complement-dependent 425,439 immunological, chronic 232, 252, 259 complement-dependent, alternative immunological, chronic, lysosomal enzyme pathway 235,236,245-247 release and 272, 277, 278 complement-dependent, classical pathway immunological, complement and 443, 444 233-235,239-245 immunological, counter-irritation and 529 counter-irritation and 529-532 immunological, in pleural cavity 232, cyclo-oxygenase and 414 253-255 delayed hypersensitivity and 237, 239, 315, immunological, lymphokine induced 239, 326 259 delayed hypersensitivity, lymphokine and immunological, non-specific 236, 245, 257 315, 326, 328, 334 inflammatory mediator assay and 573, endogenous antigen and 252, 253 579,580 FIM and 93-96 inflammatory mediator, specific antagonist histamine and 12-15, 17, 353, 355-360, and 574 365 kinin and 477,478, 505, 527 hydrolytic enzyme and 267 kininogen level and 467,503 hydrolytic enzyme release, drugs and 286 kinin release and 484---491, 493-495 5-HT and 15, 17, 361 monocytopoiesis and 93 immediate hypersensitivity and 345 mononuclear phagocyte kinetics and 84,86 immunological mechanism 231-239 mononuclear phagocyte kinetics, immunological mechanism, platelet and azathioprine and 90, 91 182-188 mononuclear phagocyte kinetics, inhibition by histamine 355 glucocorticosteroid and 88 initial response 26-56,109,571 non-immunological, autoimmunity and initial response, inhibition, chronic 252 inflammation and 579 non-immunological, chronic, lysosomal in pleural cavity 256-258 enzyme release and 273-277 kinin and 464,465,474,482,495,497-503, non-immunological, platelet and 181, 182 505 pain and 590 later stages 56-62,584 PMN and 270,271,298,299 lipoxygenase and 414 PGand 527 Jymphokine and 239, 334-336 PG hyperalgesia and 596, 597, 602, 605 lysosomal enzyme and 299-302,307 vascular event and 571 lysosomal enzyme release from PMN 270, vascular permeability and 47, 579 271, 298, 299 Inflammatory modulator, see also IT AIF and modulation 523-560 specific modulators monocytopoiesis and 92-96 algesic substance and 590 mononuclear phagocyte and 83-87, 97 definition 524 mononuclear phagocyte, azathioprine and endocrine factor 549-552 90-92 hepatic factor 547-549 mononuclear phagocyte, glucocorticosteroid humoral factor 541-554 and 87-90 local tissue factor 541-544 non-immunological mechanism 231 mediator as 257,553,554 non-immunological mechanism, neurogenic factor 554---558 endogenous antigen and 252 plasma factor 545-547 non-immunological mechanism, platelet Inflammatory reaction, see also acute and 181, 182 inflammation, chronic inflammation, non-specific 231,257 inflammatory mediator non-specific, endotoxin induced 236, 245 autopharmacologyand 12,14 pain and 587 Bk and 16,17,464,465,474,477-482 pattern reaction 12 760 Subject Index

Inflammatory reaction nomenclature 464 pattern reaction, AID and 504, 505 pain and 480, 481 platelet and 172-189 permeability factor 477,478 PMN and 298, 299 relative potency 479 polypeptide and 16 release by glandular kallikrein 465,469, PG and 414,415,598 482 PG inactivation and 406,415 release by trauma 482 proteinase release and 286 release by trypsin 471 SRS-A and 364 release, SBn and 470 thermal injury and 484 synthetic analogue 465 tissue repair and 206, 525 Kallikrein, see also glandular kallikrein, vascular event 571,580-584 kininogenase, plasma kallikrein 469,470 vascular event, pain and 587 activation 482, 490 Inflammatory sensitization, see also pain Bk release 465,469,470, 474 receptor sensitization 596, 597 chemotactic effect 119 Iniprol 482 infection and 493 Injury, see tissue injury inhibitor 470,474 Insulin in lymph 487 inflammatory modulator 552 kallidin release 464,465,469,470,474 Insulin receptor kininogen depletion 467 lymphocyte transformation and 323 methionyl-lysyl-Bk release 470,474 Intercellular junction 30,34,47,48,51 mitogenic activity 497 lymphatic 57, 59 vascular permeability and 15,475 Intercellular matrix Kaolin cell proliferation control 209 counter-irritant 532, 534 scar tissue formation and 208, 209 Shwartzman reaction and 236, 245 synthesis 208 Kaolin oedema Interferon suppression by counter irritation 528, 529 produced by mononuclear phagocyte 77 Keratan sulphate Irritated tissue anti-inflammatory factor in connective tissue 215 (IT AIF) 536--545, 559 ~-keto glutarate complement inhibition 542 collagen formation and 220 hepatic 548 15-keto PGE in blood plasma 538, 545, 546 biological activity 409,410 mode of action 542 PG biosynthesis by-product 388, 393 source 537,538,545 PG catabolism and 406, 407 Ischaemia 9-keto PG reductase 410 pain receptor sensitization 596 Kidney Isodesmosine repair 226 in elastin 222 Kinin Isoprenaline anaphylaxis and 494, 495 histamine release inhibition 350 carrageenin oedema and 487--489, 578 8-iso-PGE 1 393 destruction by kininase 472--474 Itch 595,599 disease and 498-500 Jones-Mote reaction drug effect 500-505 Arthus reaction and 240, 248 generation 471, 576 delayed hypersensitivity and 248, 249, 314 generation, inhibition of 502, 576 granulocyte and 496 histamine and 359 inactivation 472,473 Kallidin (Lys-Bk) infection and 492, 493 assay 464, 465 inflammatory reaction and 468, 482--495 bioassay 465 leucocyte migration and 482, 495 conversion to Bk 465 lymph effect 486, 487 generation 464,471 mitogenic activity 497 inactivation 473,474 neutrophil and 497 in plasma 464 oedema formation and 478 lympf effect 486, 487 pain and 465,481,591,593,594 Subject Index 761

PMN cell and 495, 496 Knee joint cavity pro-inflammatory effect 465,477---482 aspirin-like drug assay 589 release by chemical irritant 487---495 Bk-induced reflex response 590 release by kininogenase 466,469,470 endotoxin-induced inflammation in 186 release by plasmin 471 measurement of pain and analgesia 589, release by thermal injury 484---486 590 release by trauma 482 Koch phenomenon 231 release by trypsin 466 Kupffer cell release by urate crystals 490 adhesion 109 release from kininogen 465,466,471 cytochemistry 72 release, kininogen level and 467, 468 endogenous pyrogen production 619 release, regulation of 470,474 nomenclature 69 terminology 464 thermic oedema and 484---486 Labile aggregation stimulating substance tissue repair and 498 (LASS) 153-158 tissue injury and 471,482---486 endoperoxide content 154--156,387 urate oedema and 490,491 generation 387 vascular permeability and 477,478 generation, inhibition by aspirin 153, 154 vasodilation effect 477 generation, inhibition by indomethacin Kininase 472---474 153 I 473 platelet aggregation 153-160,171,188 II 473 release from platelet 145 Bk destruction 17,472---474 thromboxane content 154, 157 in biological material 473 Lactoferrin infection and 492, 493 in PMN specific granule 296 inhibition 482, 483, 497, 576 Lamellipodium 113 in leucocyte 496 Laminar flow 27 kallidin destruction 473,474 Lanthanum staining 51 terminology 464 Lathyrogenic agent, see also specific agents tissue injury and 482, 483 217 Kinin-forming enzyme, see kallikrein, Lecithin kininogenase arachidonic acid release 381 Kininogen leucocyte adhesion and 111 anaphylaxis and 495 structure 381 blood content 468 Leucocyte, see also specific cell types carrageenin oedema and 488---490 differentiation 75 class of 466, 467 kinetics in acute inflammation 85 depletion 467, 468, 488---490, 502 kinin release/destruction 495---497 heterogeneity 466, 467 mobilising factor 441 infection and 492, 493 origin 75 kinin release by heat 485,487 pavementing 28, 48 kinin release by kininogenase 464, 474 Leucocyte adhesion 48-51,109-113 kinin release by plasmin 471 Bk and 482 kinin release in tissue injury 471 chemotactic factor and 49, 55 level 467---469,477 endocapillary layer and 49, 111 lymph and 487 inflammation and 48, 111, 571 terminology 464 injury and 28,48,49,111 thermic oedema and 485 mechanism 49, 110, 111 Kininogenase, see also kallikrein specificity 51 acute phase reactant 468 vascular endothelium and 28, 48, 49, 111, Bk assay and 573 112,571 Bk release 465, 467, 573 Leucocyte chemotaxis, see chemotaxis inhibitor 470 Leucocyte locomotion kallidin release 469 chemotaxis and 115-129 kinin release 464, 467, 469---472, 474, 477, cyclic nucleotide and 125, 126 497 energy source for 125 terminology 464 ion flux and 124, 125 762 Subject Index

Leucocyte locomotion Lipoperoxide morphology of 113-115 generation 404,414 motor mechanism of 124, 125 leucocyte migration stimulation 414 Leucocyte migration, see also leucocyte pain production 481 locomotion pain receptor sensitization 481 Bk and 482 Lipoxygenase 404--406 chemotactic factor and 55, 126-129 arachidonic acid transformation 384 delayed hypersensitivity and 315-317 distribution 404, 405 inhibition by counter-irritation 530 enzymology 405,406 initial inflammatory response and 10, 26, generation of HETE 404,405 48,517 generation of HPETE 404, 405 leukotaxine induced 15 inhibition 414 lipid peroxide and 376,414 leucocyte migration and 376 measurement of 579,581,582 location 405 mediator of 55, 56 Liquoid morphology of 51-54 complement inhibitor 448,449 vascular permeability and 54, 55 Liver Leucocyte pyrogen, see also endogenous chemical toxin and 47 pyrogen homeostatic control of inflammation endotoxin induced 618,619,646 547-549,560 fever production, attenuation by atropine repair 226 634 Low molecular weight (LMW) kininogen fever production, attenuation by monoamine 466,467,474 depletion 633 Low molecular weight plasma factor 547 fever production, attenuation by PO Lymph antagonist 623, 649 inflammatory exudate removal 57,59 site of action 646 kininase activity 473 Leucocyte sticking, see leucocyte adhesion plasma kinin effect 486, 487 thermal injury and 486, 487 Leucocytosis Lymphatic vessel automodulation of inflammation and 543 acute inflammation and 59, 60 chemotaxis and 542 function 58, 59 Leucopenic factor structure 57, 58 automodulation of inflammation and 543 Lymph node produced by tissue irritation 530 T -cell proliferation in 238 Leucotaxis, see chemotaxis Lymph node permeability factor (LNPF) Leukotaxine cell-mediated immunity and 315 inflammatory mediator 15, 16 inflammatory mediator 571 Lewis' triple response 13, 29, 475 vascular permeability and 327 Linoleic acid Lymphoblast arachidonic acid biosynthesis 379 chemotaxis 128 dihomo-y-linolenic acid biosynthesis 379, Lymphocyte 380 adhesion 51,109,111-113 y-linolenic acid chemotaxis 128 arachidonic acid biosynthesis 379 delayed hypersensitivity and 315-318, dihomo-y-linolenic acid biosynthesis 379, 237,238 380 histamine effect 356-358 Lipid A in connective tissue 214 collagenase synthesis and 280 migration 51, 128 endotoxin and 618 mitogenesis 321-324,332,333 fever production 621, 626, 639, 640, 646 proliferation, inhibition by histamine 358 structure 618 transformation by lymphokine 321-324 Lipid bilayer transformation, inhibition by histamine cell-cell adhesion and 111,115 358 chemotactic recognition and 121, 122 Lymphokine 314---336 Lipid peroxidation 404,414 bioassay 323,324,326,328,329 Lipodystrophy, partial 445,447 biological action 318,319,321-331 Subject Index 763

cell-mediated immunity and 77, 239, 252, membrane lysis 267,303,482 259,334 primary 72, 297 chemotactic effect 118, 119,328-330,332, secondary 72,277,297 333 Lysosome stabilization cytotoxic activity 330, 332, 333 by adrenaline 556 definition 317 by anti-inflammatory drug 286 drug effects 333 by pregnancy serum 551 heterogeneity 331-333 by PG 553 inflammatory response and 239,252 Lysozyme 334-336 release from macrophage 73, 76, 77, 282 interferon-like activity 330 release from PMN 268, 269, 296, 304 lymphocyte transformation 321-324 Lysyl oxidase macrophage activation 77, 317, 318, collagen synthesis and 217 324-326 1X2 macroglobulin macrophage aggregating effect 317 collagenase inhibition migration inhibitory effect 239, 324-326, plasma kallikrein inhibition 470 331-333,326 mitogenic effect 239,260,321-324,332, Macromolecular polymer 333,336 kinin release and 487 plasma protein accumulation 328 Macrophage, see also mononuclear phagocyte production by lymphocyte activation 77, activation by lymphokine 77, 252, 318 324-326 production, inhibition by PGE 336,554 acute inflammation and 60,72,84-86,91, production in vitro 239,319-321 92,95,98 pro-inflammatory effect 239,326--328,333 adhesion 110 skin response 326--328 allergic arthritis and 255, 260 Lymphotoxin 279, 330 antibody production, C3 and 442 Lysine azathioprine and 90-92 in collagen 217 C3b receptor 441 Lysine hydroxylase C5 biosynthesis and 433 collagen synthesis and 220 carrageenin and 275,276 Lysolecithin cell-mediated immunity and 76, 77, 251 vascular permeability and 36 chemotaxis 118-120, 122, 126, 127, 129 Lysosomal enzyme, see also specific enzymes chronic inflammation and 87,98,251,252, 295-307 260,272-282 cartilage degradation and 283-286 classification 97 drug effect 286--288 collagenase secretion 76,280,281 lymphokine and 334 collagen synthesis stimulation 212 mediation of inflammation and 286, colony-stimulating factor 76, 77, 93 299-302,584 C receptor 71,73,75, 76 release, C3b adherence and 442 cytochemistry 71-73 release from connective tissue cell cytotoxicity 77 282-285 cytotoxic particles and 276, 277 release from macrophage 272-282 delayed hypersensitivity and 237,252,279, release from platelet IX-granule 141, 145, 315-318 160,177-180,272 dental plaque and 274 release from PMN 61,268-272,296--299, derivation 74, 75, 77-80, 83 584 elastase secretion 76, 281 release, mechanism of 267-270, 303 esterase staining 70-72,74,75 release, regulation of 303-307 exudate 73 scar formation and 210,212 fibrin and 61 suppuration and 61 fixed 70 Lysosome, see also azurophil, platelet free 70 IX-granule, PMN specific granule function 76,77,272 295-299 functional characterisation 73, 74 kininase activity in 496 glucocorticosteroid and 78, 87-90, 287 kinin-forming activity in 495, 496 granuloma formation and 87,251,252,273 764 Subject Index

Macrophage histamine release by antigen 351 history 68 histamine release by asthma 351 immune complex and 277, 278 histamine release by calcium ionophore IgG receptor 71,73, 75, 76, 277, 441 A23187 351 IgM receptor 73, 277 histamine release by compound 48/80 351 kinin release 496 histamine release by concanavalin A 351 lymphotoxin and 279 histamine release by damage 352 lysosomal enzyme release 76,212,268, histamine release by drugs 351 272--282,285--287 histamine release by IgE 182, 346, lysosomal enzyme release, complement and 348--351 279,280 histamine release by PGE2 350 lysosomal enzyme release, inhibition of histamine release by urticaria 352 286,287 histamine release by yeast 487 lysosome 72,273,277 histamine release, inhibition by histamine lysozyme 71, 73, 75, 76, 282 357 migration 60,61,84 5-HT in granules of 214, 348, 360 morphology 70 5-HT release by anaphylatoxin 234, 345 neoplastic process and 99 5-HT release by IgE 182 nomenclature 68, 69 IgE receptor 214,346,347 peroxidase staining 71--73, 75 mediator release, mechanism of 349--352 PPG and 273,274 NCF release 345, 348 phagocytosis 60, 68, 71, 73, 75, 76, 95, 251, PCA and 182 276 P AF release 348 pinocytosis 68,71,74-76,275 PG release 348 plasminogen activator secretion 76, 281 SRS-A release 345, 348, 351, 357, 362, 363 proliferation 92, 93, 260 Mediator, see inflammatory mediator and resident 73 specific mediators resolution and 60, 61, 208 Medulla oblongata storage disorder and 98 PGE 1 effect on 627 3H-thymidine labelled 78--82,84,86 Mefenamic acid Macrophage aggregating factor (MAF), see Bk-induced bronchoconstriction and 501 also lymphokine 317,318 Megakaryocyte Macrophage migration inhibition, see also platelet derivation and 138 lymphokine; migration inhibitory factor Membrane, see cell membrane allergic arthritis and 255 Membrane potential lymphokine activity 317,318,324-326, PG and 605 332, 333 Membrano-proliferative glomerulonephritis measurement of 326 (MPGN) release from lymphocyte 316 C3NeF and 430,447 reverse passive Arthus reaction and 257 complement alternative pathway and Maleopimaric acid 445--447 complement inhibitor 448 serum sickness and 243 Malondialdehyde (MDA) Meningococcal infection generation 385, 387, 388, 396, 398 suppuration and 62 pro-inflammatory effect 375 Mepacrine Mast cell phospholipase inhibition 178, 380, 411 activation by IgE 182,214,231,346,348 platelet aggregation inhibition 411 anaphylaxis and 231,346--352 rheumatoid arthritis and 412 Bk-A release 348,350 Mepyramine (Neo-Antergan) connective tissue and 214 anaphylatoxin shock inhibition 13 degranulation 234, 236, 345--347, 573 anti-inflammatory effect 488, 575 distribution 347,348 histamine theory and 14 ECF-A release 345,348,350 histamine Type I antagonist 353 heparin in granules of 214,347 oedema formation and 488 histamine in granules of 214, 347, 348, 573 Metabolic demand histamine release by anaphylatoxin 234, blood flow and 213, 222 345,351 capillary formation and 210,213 Subject Index 765

cell proliferation and 206, 207 derivation 74,75 scar maturation and 222 functional characterisation 73,74 scar tissue and 208 morphology 69,70 Metarteriole 27 nomenclature 69 Methionine 3H-thymidine labelled 78 in collagen 218 Monocyte Methionyl-Iysyl-bradykinin (Met-Lys-Bk) acute inflammation and 84--86, 90-96 bioassay 465 adhesion 51 pain and 480 azathioprine and 90-92 permeability factor 478 C3b receptor 441 relative potency 479 chemotaxis 118, 120-122, 126, 127, 440, release 471,482 442 terminology 464 chronic inflammation and 87 Methysergide classification 97 anti-inflammatory effect 575 colony stimulating factor 76, 77 drug-induced fibrosis and 225 C-receptor 71,73 platelet aggregation and 151 cytochemistry 71-73 PG hyperthermia and 634 derivation 74, 75 Metiamide endogenous pyrogen production 619 histamine Type 2 antagonist 14, 350, 353, function 76 354,356,357 functional characterisation 73, 74 Microcirculation glucocorticosteroid and 87-90 blood flow, change in 580,581 IgG receptor 71,73,441 function 27 kinetics 80-83, 86 inflammatory mediator and 574 migration 51, 126, 127 inflammatory response and 571, 581, 582 morphology 70 pressure change in 581,582 nomenclature 68, 69 structure 27, 30 peroxidase staining 71-73,76 Microfilament production 80-83, 86, 89-96 leucocyte locomotion and 124 proliferation 78, 87 Microglial cell 3H-thymidine labelled 78-82,86 endogenous pyrogen release 647 Monocyte production inhibitor (MPI) 96 nomenclature 69 Monocytopenia Microtubule induced by glucocorticosteroid 78, 89 leucocyte locomotion and 124 mechanism of 89 lysosomal enzyme release and 304--306 Monocytopoiesis mediator release and 349-352 humoral control in inflammation 92-96 Mid-brain monocyte kinetics and 83 site of pyrogen action 620, 624, 648 Monocytosis Migraine headache inflammatory response and 93-96 pain receptor sensitization by 5-HT and Mononuclear phagocyte, see also leucocyte 596,606 and individual cell types Migration inhibitory factor (MIF), see also acute inflammation and 84--86,91-98 lymphokine adhesion 109 allergic arthritis and 255 antibody formation and 76, 77 Arthus reaction and 255 azathioprine and 90, 92 inhibition by histamine 358, 360 cell-mediated immunity and 77,251 lymphokine activity 317,318 chemotaxis 126,127,328,329 production 320 chronic inflammation and 87,97,98,251, release from lymphocyte 316 252,276 Mitogenic factor (MF), see also lymphokine classification 97 317,318,320 C-receptor 71, 73, 75 lymphokine activity 317,318 culture 74 production 320 cytochemistry 70-73 Modulator, see endogenous modulator cytotoxicity 77 Monoblast delayed hypersensitivity and 237, 315 cytochemistry 71, 72 derivation 74,75, 77-80 766 Subject Index

Mononuclear phagocyte Necrotaxis 119 endogenous pyrogen production 619 Neo-Antergan, see mepyramine esterase staining 70, 71, 74, 75 Nephritis exocytosis 87 immune complex and 244 function 76, 77, 83 Nephrosclerosis 211 functional characterisation 73, 74 Neuraminidase fusion 87 leucocyte adhesion and 112, 113 glucocorticosteroid and 87-90 leucocyte chemotaxis and 122 granuloma formation and 87,97, 98, 251, Neurotransmitter 252 inflammatory modulation and 555-557 history 68 Neutral proteinase, see also specific enzymes iden tifica tion 69 complement activation and 301 IgO receptor 71, 73, 75 degradation of connective tissue 286 kinetics 77-87 drug effects 287 lysosomal enzyme release 76, 77, 268, 277, release from macrophage 272, 273, 285 280---282 lysozyme secretion 71, 76 release from PMN 270 migration 60---62, 84, 126, 127 release, mechanism of 268 morphology 69, 70 Neutrophil neoplastic process and 97-99 adhesion 51, 110, 114 nomenclature 68, 69 Arthus reaction and 183, 184,443,444 peroxidase staining 71-73, 75 C3b receptor 441 phagocytosis 71, 73, 75, 76, 87 chemotaxis 126 pinocytosis 71, 74, 75, 87 chemotaxis by casein 120 proliferation 78 chemotaxis by complement factor 118, resolution and 60,61 129,234,440,441 secretory function 76, 77 chemotaxis by cytophilic antibody 119 storage disorder and 97, 98 chemotaxis by N-formyl methionyl peptide 3H-thymidine labelled 78-82,86 122 Mononuclear phagocyte system chemotaxis by haemoglobin 121 classification 97 chemotaxis by HSA 120, 121 disease and 97-99 chemotaxis by lymphokine 118, 328, 329 regulation in acute inflammation 95, 96 chemotaxis, mechanism of 124 Morphine con tact inhibition 114 analgesic mechanism 601,607,608 endogenous pyrogen production 618, 619 post-operative pain and 601 gout and 490 PO hyperthermia and 634 hind paw oedema and 530 C-mucopolysaccharide-peptidoglycan (PPO) histamine effect 356, 357 chronic inflammatory lesion and 273 kinin release 490, 497 lysosomal enzyme release and 273, 274 lysosomal enzyme release 442, 584 macrophage and 273 mediator release 345 Multiple sclerosis migration 51, 126, 127 defective POE reactivity and 336 SRS-A source 362, 363 Mycoplasma Neutrophil chemotactic factor (NCF) arthritis and 256 release from basophil 345, 348 Myocardial infarction release from mast cell 345, 348 kininogen depletion 467 specificity 126 Myo-fibroblast 224 Newborn calf serum contractile filament in 210,224 monocyte production and 81, 82, 84----86 scar formation and 210 Nicotinamide-adenine dinucleotide (reduced) Myocin (NADH) leucocyte locomotion and 124 PO biosynthesis and 394----396 lysosomal enzyme retention and 269 Nicotinamide-adenine dinucleotide phosphate Nargase (reduced) (NADPH) kinin release 471 PO biosynthesis and 394----396 Necrosin Nicotinic acid inflammatory mediator 15 fever and 635 Subject Index 767

Nociceptor aspirin-like drug and 481, 589, 590, 597, pain 591 601-608 Non-steroid anti-inflammatory drug (NSAID), Bk-induced 480,481,589,593,594,596, see also aspirin-like drug, and specific 598-600,604 drugs experimental 606 anti-Bk effect 501 histamine induced 481,593,598,599 Bk-induced bronchoconstriction and 501 5-HT and 481,592,593,596,597,608 oc-2-glycoprotein inhibition 559 inflammatory mediator and 481,592-595, gouty attack and 490 608 lymphocyte activation and 333 measurement of 480, 588-590, 596, 597 lysosomal enzyme release inhibition 287, narcotic analgesic and 481, 601, 608 288 pathological 606 modulation of inflammation and 559 plasma kinin and 16, 17, 465, 480, 481, neutrophil enzyme release inhibition 490 591,593,594 platelet inflammatory mediator release PG and 374,481, 590, 598-601, 608 inhibition 172, 173 substance P induced 481,592,593 platelet PGE2 synthesis inhibition 173 suppression by counter-irritation 527, 531 PG metabolite excretion and 404 swelling and 480, 595 PG synthesis inhibition 173, 575, 580 types of 590,591 Noradrenaline Pain receptor 590-597 aggregating agent 148 identification 591,592 fever production 632, 633 nociception 591 hypothermic effect 627 sensitization 480, 595 PG biosynthesis and 395 sensitization by 5-HT 481, 594, 596, 600, 606 Oedema, see also specific oedemas sensitization by inflammation 592, 594, arachidonic acid metabolite and 375 596,597 Bk release in 484 sensitization by ischaemia 596 experimental, measurement of 579,582 sensitization by PG 481, 595, 597-601, formation by Bk 16,480 604-606,608 history of inflammation and 6, 10 sensitization by synergism of algesic initial inflammatory reaction and 26, 59 substances 596 Oestriol dihemisuccinate sensitization, mechanism of 596,604-606 anti-inflammatory effect 550,551 stimulation 480, 591, 592 Oestrogen stimulation by substance P 592, 593 anti-inflammatory effect 550,551,560 stimulation, chemical 480,591-594 Orgotein stimulation, hydrogen concentration and inflammatory mediator 549 593,594 Osmotic reflection coefficient 581 stimulation, mechanical 480, 592, 596 Osteoclast stimulation, potassium ions and 593, 594 nomenclature 69 stimulation, thermal 591, 592 Osteoid 213 stimulation, tissue damage and 591, 592, Osteomyelitis 594 abscess 62 Pancreatic kallikrein 470 and w-oxidising system p- Pancreatitis (acute) distribution 408 kinin activity 499 PG catabolism and 406, 407 kininogen depletion 467,499 6(9)-oxy-ll,15-dehydroxy prosta-7,13-dienoic Panting acid cyclo-oxygenase product 393 thermoregulation and 628, 629 Oxygen tension Papaine cell proliferation in scar formation and 213 kinin release 471 Oxyphenbutazone Paracetamol, see acetaminophen co-oxygenation 401 Passive cutaneous anaphylaxis (peA) complement and 182,183 Pain, see also hyperalgesia 588-608 histamine release in 182, 183 acetylcholine induced 481,593 hyperalgesia and 605 arachidonic acid metabolite and 375, 601 inhibition by histamine 356 768 Subject Index

Passive cutaneous anaphylaxis (PCA) by PMN 233,269,271,297 kininogen depletion in 495 complement and 76,233,271,441,442 platelet and 182, 183 definition 76 precipitating antibody and 182, 183 ECF release and 363 production 182,235 history of inflammation and 11 reaginic antibody and 182, 183 immune complex and 233, 271, 277, 303, Pattern reaction 441 of inflammation 11, 18 IgG and 76,441,442 D-penicillamine inhibition by cytochalasin B 268-270,304 collagen and 217 lysosomal enzyme release and 267, 268, Pentobarbitone sodium 270,271,276,281 PG hyperthermia and 635, 642 neutrophil activation 363 Pepsin of C3b-coated immune complex 441, 442, Met-Lys-Bk release 471 444 Peptidase P of cytotoxic agent 267,272,276 kininase in kidney 473 of endotoxin 185 Peptone shock of virus by platelet 187 SBTI and 470 opsonisation and 12, 73, 76, 233 Periendothelial cell Phagolysosome 297 actomyosin in 38 Phagosome 297 basement membrane 31 PHD, see also thromboxane B2 structure 30 generation 391,392 Peripheral nerve fibre Phenazone analgesic action of aspirin-like drug and Bk-induced bronchoconstriction and 501 602,603,607 Phenbenzamine transmission of pain 591 histamine theory and 14 Permeability factor, see also specific mediators Phenoxybenzamine Bk as 477 kininogen level and 469 cationic protein as 176 PG fever and 633 complement component as 439 Phen to lamine duration of effect 475 PG fever and 633 histamine-type, gap formation and 34, 35, Phenylbutazone 38 anti-aggregatoryeffect 188 histamine-type, venular leakage and 35,38, anti-Bk effect 501 45 carrageenin antagonist 504 in platelet Q(-granule 176 kinin release inhibition 502 in PMN azurophil 270 lysosomal enzyme release inhibition 287 kallidin as 477 pain and 481 leucocyte adhesion and 55, 112 protein breakdown inhibition 482 leucocyte migration and 53, 54 Phenytoin lymphatic vessel and 59 drug-induced fibrosis and 225 neutral proteinase as 270 Phloridzin Peroxidase complement inhibitor 448, 449 in lymphocyte 75 Phorbol myristate acetate (PMA) in mononuclear phagocyte 71-73,75 lysosomal enzyme release from PMN and in PMN azurophil 296 298 Pertussis vaccine pleurisy 258 Phosphatide Peyronies disease 224 arachidonic acid in 380 PF/dil cyclo-oxygenase activity and 382 prekallikrein and 472 dihomo-y-linolenic acid in 377,380 PF/phag Phosphatidyl choline vascular permeability and 302 arachidonic acid source in platelet 159, Phagocyte, see mononuclear phagocyte 178,381 Phagocytosis dihomo-y-linolenic acid in 377 by macrophage 76, 269, 276, 277 Phosphatidyl ethanolamine by mononuclear phagocyte 73, 75, 76, 83 arachidonic acid in source in platelet 381 by platelet 185 dihomo-y-linolenic acid in 380 Subject Index 769

Phosphatidyl inositol extravasation, vascular permeability and arachidonic acid source in platelet 159, 30,36,582,583 178,381 filtration and 582 Phosphoadenosine phosphosulphate platelet defect and 165 connective tissue polysaccharide and 215 Plasma skimming 27 Phosphodiesterase inhibitor Plasmin anti-aggregatoryeffect 150 complement and 449 Phospholipase connective tissue degradation and 286 arachidonic acid release 177, 178,380 Factor B activation 429 inhibition 178,380,410-412 fibrinolysis 61,210 in platelet IX-granule 159,177,178 inhibition by aprotinin 470, 482 PG synthesis and 177,380,382,410 inhibition by EACA 449,482 stimulation by adrenaline 159 kinin release 465,469--471,482 stimulation by Bk 380 oedema formation inhibition 482 stimulation by thrombin 159 resolution of inflammation and 61 Phospholipase A1 scar tissue generation and 210 arachidonic acid release 177, 178 Plasminogen in platelet IX-granule 177, 178 activation by active Hageman factor 449 PG synthesis and 177 activation by clotting factors XI and XII 61 thrombin and 178 activation, inhibition by EACA 449 Phospholipase A2 activator from macrophage 77,281,282 arachidonic acid release 178, 380 activator from mononuclear phagocyte cyclo-oxygenase activity regulation 380, 61, 76 382 activator in lysosome 301 inhibition 411 complement and 449 in platelet dense body 178 fibrinolysis and 61,210 PG synthesis and 380,410 resolution of inflammation and 61 Phospholipid scar tissue generation and 210 arachidonic acid source 380 Platelet arachidonic acid source in platelet 177,381 amorphous coat 139 cell-cell adhesion and 111 anaphylactic shock and 183 cyclo-oxygenase substrate and 377, 380, Arthus reaction and 183,184,189 410 chemotactic factor 173, 175, 176, 178 dihomo-y-linolenic acid source 377 clot retraction and 164 PG synthesis and 382,410 count 138 Phytohaemagglutinin (PHA) cyclo-oxygenase deficiency 171, 189 lymphocyte transformation and 322, 323 cYclo-oxygenase inhibition 159, 169, 171, Pinocytosis 178,179 by macrophage 76, 297 cyclo-oxygenase product 381,382,387 by mononuclear phagocyte 68, 74-76, 83 defect 164,166--172 capillary permeability and 34 dense-tubular system 140 history of inflammation and 68 endoperoxide generation 142, 145, 146, lysosomal enzyme release and 275 154,159,160,178 macropinocytosis 76 endoperoxide generation inhibition 158 micropinocytosis 76, 297 function 138, 139 of carrageenin 275 graft rejection and 187, 189 Plasma cell haemostasis and 163-172, 188 in connective tissue 215 histamine release 173 Plasma kallikrein 469,470 histamine release in anaphylactic shock activation 470, 482 189 Bk release 465,466,474 HHT generation 387 glandular kallikrein and 469 5-HT in dense body 141,151,348 inhibitor 470 5-HT release 160,173 Plasma kinin, see kinin 5-HT release in anaphylactic shock 189 Plasma kininase (kininase II) 473 5-HT release, migraine and 596,606 Plasma protein immune adherence 233, 236, 237 accumulation, lymphokine and 328 inflammatory mediator release 173, 189 770 Subject Index

Platelet impaired 165--172 inflammatory mediator release, indirectly induced by adrenaline 158, 159 IgE mediated 348 indirectly induced by ADP 158, 159 inflammatory response and 172,181-189, indirectly induced by collagen 159, 160 584 indirectly induced by ristocetin 163 LASS generation 145, 154 indirectly induced by thrombin 160, 161 lipid metabolism 142 indirectly induced by zymosan 161 lipoxygenase 158, 159,404,414 inflammation and 181-188 lysis by complement 442 inhibition by aspirin-like drug 141, 146, lysosomal enzyme 141,177-180 153, 158-160, 188 lysosomal enzyme release 272 inhibition by phosphodiesterase inhibitor microfilament 140 150 microtubule 140 inhibition by POE1 150, 155, 161, 163, 168, migration 176 172 morphology 139-142 LASS and 153-159 peA and 182 measurement of 147, 148 permeability factor 176 mechanism of 142, 144-146, 148-163, phospholipid synthesis 142 188 PO biosynthesis 153, 159, 173, 178, 179, platelet granules and 141 584 platelet morphology and 139 PO biosynthesis inhibition 153, 169, 173, potentiation by POE2 146, 155, 168, 169, 401 171 PO synthetase 153, 178 second phase 148 protein synthesis 142 sedond phase induced by adrenaline 141, Shwartzman reaction and 184-186,189 145, 146, 158, 159 surface connecting system 140 second phase induced by ADP 141, 145, thromboxane generation 154, 155, 157, 146, 158, 159 391,392 second phase, inhibition by aspirin-like drug trilaminar plasma membrane 139 141, 146, 153 young 138 second phase, potentiation by POE2 156 Platelet activating factor (PAF) second phase, storage pool disease and 167 IgE-mediated release and 348,361 Shwartzman reaction and 185,186,247 platelet 5-HT release and 361 storage pool disease and 167-171 Platelet adhesion 139,142-144 thromboxane A2 and 154, 157, 159, 390, impaired 165, 166 392 measurement of 147, 148 Platelet dense body 141 ristocetin-induced aggregation and 163 platelet release reaction and 145 thrombosis and 51 storage pool disease and 169 Platelet aggregation 138-189 Platelet factor 3 (PF 3) anaphylaxis and 183 clotting process and 164, 177, 185, 236 arachidonic acid and 146, 153, 169 deficiency 172 arachidonic acid metabolite and 375 haemostasis and 188 Arthus reaction and 184 in ex-granule 177 aspirin-like defect 171 platelet surface and 139, 177 bacteria and 186 release, ADP-induced aggregation and 139 co-factor 144-145 release by endotoxin 185, 235 complement and 234, 442, 443 release, immune adherence and 236 directly induced by adrenaline 151, 152 Platelet factor 4 (PF 4) directly induced by ADP 150 clotting process and 164 directly induced by 5-HT 151 haemostasis and 188 directly induced by thrombin 152 heparin and 176 endoperoxide and 154, 159, 161, 186, 189 in dense body 176 endoperoxide P002 and 156,157 in ex-granule 176 endoperoxide POH2 and 155, 156 Platelet ex-granule 141,272 first phase 148 cationic protein in 176 first phase induced by ADP 145 kinin formation and 176 HETEand 414 lysosomal enzyme in 180 SUbject Index 771

lysosomal enzyme, tissue damage and 179, connective tissue and 214 272 IgG receptor 441 PF3 in 177 inflammation and 298,299,584 PF4 in 176 kinin forming activity 495 phospholipase in 177 life span 60 platelet aggregation mechanism and 160 lysosomal cationic protein 271, 302, 303 platelet release reaction and 141, 145 lysosomal enzyme, inflammation and 298, Platelet release reaction 145, 146 299-302,584 aspirin-like drug and 141, 146 lysosomal enzyme release, complement and chemotactic activity and 176 271 endoperoxide and 146, 155, 157 lysosomal enzyme release, connective tissue graft rejection and 187 degradation and 286 induced by influenza virus 187 lysosomal enzyme release, cyclic nucleotide mechanism of 146,160 and 304-306 oxygen burst in 146 lysosomal enzyme release, cytochalasin B phospholipase and 178 and 286--270,304 platelet adhesion and 139 lysosomal enzyme release, immune complex platelet granules and 141 and 270 release I 145, 146 lysosomal enzyme release, mechanism of release I induced by adrenaline 141, 146, 269, 270 158 lysosomal enzyme release, NSAID and 287 release I induced by ADP 141,146,158 lysosomal enzyme release, regulation of release I induced by collagen 146 303-306 release I induced by thrombin 146, 160 lysosomal enzyme release, selective 268- release II 145, 146 271 release II, induced by collagen 141, 146 lysosomal release, toxic particles and 272 release II, induced by thrombin 141, 160, lysosome 268,296--299 176,178 membrane redistribution 115 Platelet shape change 144 migration 51,60,61 first phase aggregation and 145, 161 permeability factor in 271 induced by adrenaline 152 phagocytosis 297, 298 induced by ADP 150 phagocytosis, cytochalasin Band 269 induced by ADP, collagenase release and phagocytosis, immune complex and 233, 179 234 induced by PGHz 155 phagocytosis, lysosomal enzyme release and measurement of 148 268,270,303 microtubule and 140 phagocytosis of toxic particles 272 platelet energy metabolism and 150, 152 resolution of inflammation and 60 Platelet spreading 142-144 scar tissue formation and 210 microtubule and 140 Shwartzman reaction and 236, 246, 299 Platelet swelling, see platelet shape change suppuration and 62 Plethysmography tissue injury and 299 measurement of vascular change 17, 581, Polymorphonuclear leucocyte lysosome 286, 582 296--298 PMN-kinin 495,496 inflammation and 298,299 Pneumoconioses 276 Polymorphonuclear leucocyte specific granule Polyarteritis nodosa 268,296 immune complex and 242, 243 Polypeptide, see also specific polypeptides Polymorphonuclear leucocyte (PMN), see also in inflammatory reaction 16,478 specific cell types smooth muscle effect 478 abscess formation and 62 vascular permeability and 16,478 antibody-dependent cellular cytotoxicity Polyphloretin phosphate and 305 PG inactivation inhibition 413 Arthus reaction and 241,242,298 Polyunsaturated fatty acid, see also fatty acid C3b receptor 441 'activating factor' generation and 392 cell-mediated immunity and 237 chemiluminescence and 401 chemotaxis, anaphylatoxin induced 233,234 endoperoxide generation and 382 772 Subject Index

Polyunsaturated fatty acid Prolyl hydroxylase PG synthesis and 374, 382, 414 collagen synthesis and 214 'prostaglandin M l' generation and 393 Promonocyte transformation by cyclo-oxygenase 376, acute inflammation and 86, 90, 92 382,392,414 bone marrow content 80, 82 transformation by lipoxygenase 376, 404, bone marrow content, hydrocortisone and 405,414 89,90 Polyvinylpyrrolidine cell-cycle time, azathioprine and 92 counter-irritation and 529 cell-cycle time, hydrocortisone and 89, 90 kininogen depletion 467,490 cell-cycle time, inflammatory response and Polyvinyl sulphate 86,92 complement inhibitor 448, 449 cell-cycle time, monocyte production and oedema formation and 489 80, 83, 89, 92 Pore system 33, 34 cytochemisty 71, 72 Posterior hypothalamus derivation 74, 75 fever production and 620, 622, 624, 627 functional characterisation 73, 74 potassium morphology 70 pain receptor stimulation 593, 594 nomenclature 69 PPG, see C-mucopolysaccharide-peptido• 3H-thymidine labelled 78, 79, 86 glycan Pronase Practolol Factor B activation 429 drug-induced fribosis and 225 inhibition 482 Precapillary sphincter 27 kinin release 471 Prednisolone Propranolol lysosomal enzyme release and 287 p-adrenoceptor antagonist, histamine Peferential channel 27 release and 350 Pregnancy p-adrenoceptor antagonist, lysosomal modulation of inflammation 551 enzyme release and 556 Prekallikrein kininogen depletion inhibition 469 activation to plasma kallikrein 470, 490 PG fever and 633 depletion 489 Prostacyclin (PG 1z; PGX) Hageman factor activation and 466, 472, generation from platelet endoperoxide 158 490 platelet adhesion and 142 purified 470 thromboxane A and 158 Pre-optic anterior hypothalamus z Prostaglandin (PG), see also specific PGs; adenine nucleotide injection into 636, 637 prostaglandin biosynthesis noradrenergic terminal destruction 633 antagonist, PG fever and 632, 649 pentobarbitone sodium and 635 PG in CSF and 644, 649 antagonist, specificity of 575, 580 PGEt injection into 625-630, 633, 634, anti-inflammatory modulator function 637,646 257, 350, 553, 554, 586 PGEz injection into 627 aspirin-like drug analgesic action and PGE synthesis in 637,640, 645, 646 604-607 pyrogen injection into 621,624,646 body temperature and 617-649 site of PG febrile action 617, 626, 632, 646 Bk-induced bronchoconstriction and 376 site of pyrogen action 620, 646 Bk-induced hypotension and 376 unspecific fever and 643 calcium ions and 605 Pro-aggregatory substance, see also specific carrageenin oedema and 489, 578 substances 139, 145, 158-164 catabolism, chemistry of 406 Procaine catabolism, enzyme in 406,408 anti-phospholipase activity 411 catabolism, impaired 412,644,645 Procollagen 218-220 catabolism, inhibition of 413-415, 632 Pro-collagen peptidase 220--221 chemotactic effect 374 Proline collagen synthesis and 554 in collagen 216,218 delayed hypersensitivity and 334 Proline hydroxylase endotoxin shock and 412 collagen synthesis and 211, 220 fever mediation 374, 637, 645 Subject Index 773

fever production 621, 625, 626, 632, 634, urinary metabolite excretion, inhibition by 635,637,646,647,649 NSAID 404 fever production, anaesthetics and 635 vascular effect 374,583 fever production, antipyretics and 630- Prostaglandin Al (PGA1) 632 inactivation 408, 409 fever production, atropine and 634 Prostaglandin A2 (PGA2) fever production, chlorpromazine and 634 inactivation 408, 409 fever production, cAMP and 635---{)37 Prostaglandin antagonist fever production, drug effects 630--635 prostaglandin fever and 632, 649 fever production, monoamine depletion and pyrogen fever and 649 632-634 Prostaglandin biosynthesis fever production, morphine and 634 cc-adrenoceptor and 152 fever production, nicotinic acid and 635 arachidonic acid and 380, 384 fever production, pre-optic anterior co-factor and 394, 395 hypothalamus and 632, 637, 646, 647 cyclo-oxygenase and 382, 396, 402, 414 fever production, PG antagonist and 632 cytochrome P450 and 402 fever production, theophilline and 635 dihomo-y-linolenic acid and 380, 383, 384 histamine potentiation 578, 583 endoperoxide and 384,388-390 hyperalgesia 374, 414, 598, 600, 601, 605 in brain 153 inactivation 406,410 in inflammatory exudate 153 inactivation, inhibition of 412--414 in macrophage 76,77,334 inactivation, sites of 408, 409 in platelet 152, 153, 173, 179, 401 in CSF, fever and 637-641, 648, 649 in pre-optic anterior hypothalamus 637, in inflammatory exudate 374,481, 573, 604 644-646,648,649 inflammatory mediator 374,414,573-576, in spleen 152, 153 580 inhibition by anti-phospholipase drug lymphokine and 334, 335 410--412 metabolism - see catabolism inhibition by antipyretic agent 617, 631, nomenclature 377 632, 637, 645, 646, 648 pain production 374, 481, 598 inhibition by aspirin-like drug 173, 179, pain receptor sensitization 481, 590, 595, 335,400,401,575,576,578,580 599-601,604-606,608 inhibition by corticosteroid· 335,412 receptor 350,580 inhibition by NSAID 575 release, anaphylaxis and 348 irihibition by non-steroid oestrogen 551 release, Bk and 488, 501, 578 non-specific fever and 642, 643 release, inflammation and 598, 604, 605 optimal conditions for 396--400 release, sequential 578 phospholipase and 380,410 schizophrenia and 644, 645 platelet aggregation and 152, 153, 179 structure 378 polyunsaturated fatty acid and 374, 377, synthesis, see prostaglandin biosynthesis 382,384,414 temperature response at different ambient pyrogen and 622, 637, 644-648 temperatures 628 rheumatoid joint and 334 temperature response in bird 627 thrombin and 153 temperature response in cat 623 tissue sites of 383, 384 temperature response in Echidna 627 Prostaglandin D2 (PGD2) temperature response in human 625 anti-aggregatory effect 157, 158 temperature response in mouse 627 bioassay 577 temperature response in monkey 624 co-factor requirement 395 temperature response in rabbit 624 generation 385, 388, 389 temperature response in rat 626 generation, optimal conditions of 396, 398 temperature response in sheep 625 platelet and 577 temperature sensitive neurone and 629 pro-inflammatory effect 173, 375, 577 theory of fever 645---{)49 structure 378 tissue injury and 483 Prostaglandin E (PGE; E-type PGs), see also turnover 402 PGE1 and PGE2 urinary metabolite excretion 402, 403, 406 adjuvant arthritis suppression 254 774 Subject Index

Prostaglandin E (POE; E-type POs) body temperature modulation 631 allergic response regulation 336 Bk-induced pain and 481, 501 anti-inflammatory modulator function Bk-induced vascular permeability and 489 254,257,554 Bk reflex potentiation 599 aspirin treatment and 401 carrageenin oedema and 489 biosynthesis by macrophage 336, 554 chemotaxis and 175 biosynthesis, co-factor requirement of 395, cAMP elevation 150,161,305,322,350,554 396 cAMP elevation, inhibition by morphine biosynthesis from endoperoxide 388, 389 cyclo-oxygenase and 383 biosynthesis in pre-optic anterior hypo- electro cortical sleep 628, 629 thalamus 640, 643 fever production 617, 623, 625, 627, 628, biosynthesis, lymphokine and 325 630,646 body temperature effect 623 fever production, anaesthetic and 635 chemotaxis and 173 fever production, anterior hypothalamus chronicity of inflammation and 336, 554 and 624,626 cAMP and 554 fever production, antipyretic agent and fever mediation 617, 637, 640, 645 631,632 fever production 645 fever production, atropine and 634 fever production, antipyretic agent and fever production, chlorpromazine and 634 645 fever production, monoamine depletion and headache and 598 633,634 hyperalgesia 600 fever production, morphine and 634 hyperthermia 626 fever production, nicotinic acid and 635 hypothermia 627, 629 fever production, PO antagonist and 632 inactivation 406 fever production, theophilline and 635 in CSF in fever 637,638,640,641,645,648, hyperalgesia 598,600 649 hyperthermia 62~630, 647 lymphocyte activation inhibition 333, 335 hypothermia 627,629,647 336,554 hypothermia, indomethacin and 631 lymphocyte reactivity, defective, and 336, inactivation 408--410 554 inactivation, inhibition by indomethacin lymphocyte transformation and 322 413 lymphokine suppression 332, 333, 336, 554 in CSF in fever 637, 638 metabolism 406,410 itch and 599 nomenclature 377, 378 leucocyte reactivity, defective, and 336 pain production 598 lymphocyte activation and 333, 554 pain receptor sensitization 599, 600 lymphocyte transformation and 322 peripheral level in man 402 lymphokine suppression 332, 333, 554 platelet aggregation modulation 139, 155, multiple sclerosis and 336 157 nomenclature 377,378 pro-inflammatory effect 375 platelet migration and 176 rheumatoid arthritis and 336, 554 platelet shape change and 144 structure 378 pro-inflammatory effect 375 turnover 402,403 PODH inhibition 412 urinary metabolite excretion 403, 406 structure 378 vascular effects 578 temperature sensitive neurone and 630 Prostaglandin E J (POEd turnover, daily 403 adjuvant arthritis suppression 554 urinary metabolite excretion 402, 403, 406 algogenic substance and 481 Prostaglandin E2 (POE2) anti-aggregatory effect 150, 155, 161, 163, biosynthesis from arachidonic acid 384, 172,382 385 anti-inflammatory modulator function 554 biosynthesis from dihomo-i,-Iinolenic acid biosynthesis, co-factor requirement of 395 384 biosynthesis from arachidonic acid 384 biosynthesis from en do peroxide 154, 389, biosynthesis from dihomo-y-linolenic acid 390,393 384 biosynthesis induced by thrombin 160 body temperature effect 623-630 biosynthesis in platelet 145, 160, 173 Subject Index 775

biosynthesis, optimal conditions for 396, pain production and 601 398,399 platelet aggregation defect and 168, 171 body temperature effect 623-630 platelet aggregation mediation 154, 155, chemotaxis and 175 158-161, 163, 175, 186, 188 cAMP elevation 350 platelet release reaction and 146,155--157, endotoxin shock and 412 166, 168, 169, fever production 624, 625, 627 PO metabolite and 403 fever production, antipyretic agent and 631 storage pool disease and 167-169, 171, hyperthermia 626,629,630,647 189 hypothermia 627,629,647 thrombasthenia and 166 hypothermia, indomethacin and 631 thrombosis and 156, 188 inactivation 406, 408 transformation to HHT 387,388 inactivation, impaired 412 transformation to MDA 387 inactivation, inhibition of 413,414 transformation to PO 388-390 in CSF in fever 637-641, 644 transformation to thromboxane 154, 157, in CSF in fever, catalepsy and 644 158,390-392 in CSF in fever, non-specific fever and 642 vasoconstriction and 164 in CSF in fever, pentobarbitone sodium Prostaglandin endoperoxide 0 1 (POOl) anaesthesia and 642 transformation to thromboxane 158 inflammatory mediator 173, 573 Prostaglandin endoperoxide O2 (P002; lymphocyte activation and 333 15-hydroperoxy POR2) lymphokine suppression 332, 333 biosynthesis 385, 386 metabolism, impaired 412 direct aggregating effect 154 metabolism, inhibition of 413,414 in LASS 154, 387 metabolism in man 407 inRCS 392 nomenclature 377,378 platelet release reaction and 146, 157 platelet aggregation by LASS and 153 pro-inflammatory effect 375, 554 platelet aggregation by POH2 potentiation second phase aggregation mediation 159 156,169,171 structure 378 platelet migration and 176 transformation to HHT 387 platelet release reaction and 145 transformation to POE2 390 platelet release reaction potentiation 146 transformation to thromboxane 390-392 pro-inflammatory effect 173, 375 transformation to thromboxane in platelet storage pool disease and 169, 171 154, 157 structute 378 Prostaglandin endoperoxide HI (POHl ; turnover, daily 403 PORt) urinary metabolite excretion 402, 403, 406 biosynthesis from dihomo-y-linolenic acid Prostaglandin E3 POE3) 383 biosynthesis 384 platelet aggregation and 158 Prostaglandin endoperoxide, see also specific transformation to PO 388 endoperoxides transformation to thromboxane in platelet cOMP elevation and 160 158 cyclo-oxygenase activity and 382-384 Prostaglandin endoperoxide H2 (POH2; cyclo-oxygenase deficiency and 168, 171, POR2; 15-hydroxy endoperoxide) 189 biosynthesis 385,386 direct aggregating effect 155, 157, 168, 169, biosynthesis, inhibition by aspirin 146, 156, 175 169 generation 159, 160, 168, 384, 386, 394 biosynthesis in platelet 146,148,154 generation inhibition by aspirin 156, 179, biosynthesis, oxygen consumption and 146 188 direct aggregating effect 146, 148, 154, 155 generation in platelet 142, 145, 154, 160, direct aggregating effect, adrenaline and 169,178 151 generation, stimulation by thrombin 160, direct aggregating effect, inhibition by POEI 164 155 haemostasis and 164, 171, 188, 189 in LASS 154, 387 inflammation mediation 554 inRCS 392 LASS and 154 platelet release reaction and 146, 155 776 SUbject Index

Prostaglandin endoperoxide H2 biological activity 410 platelet release reaction, potentiation by PG catabolism and 406, 408 PGE2 156, 169 PG turnover and 402-404 pro-inflammatory effect 375 structure 378 second phase aggregation mediation 154, urinary excretion 402, 403, 406, 408 157 urinary excretion, inhibitation by NSAID storage pool disease and 159, 169 404 structure 378 Prostaglandin M 1 393 thrombocytopenia and 156 Prostaglandin ,j 13 reductase transformation to HHT 387 distribution 408 transformation to PG 388-390 PG catabolism and 406,407 transformation to thromboxane in platelet Prostaglandin synthetase, see also cyclo- 154, 157 oxygenase, prostaglandin biosynthesis Prostaglandin endoperoxide reductase biochemical properties 397, 398, 400 PGF formation 390 characterisation 382 Prostagladin F (PGF) distribution 383 co-factor requirement 395 in brain, antipyretic activity and 645, 646 generation 388,390 in brain, inhibition by aspirin-like drug 607 inactivation 406 in brain, inhibition by indomethacin 646 pro-inflammatory effect 375 in brain, inhibition by paracetamol 153, structure 378 645,646 turnover 403 in brain, inhibition by sodium acetyl Prostaglandin F la (PGF I.) salicylate 646 hyperthermic effect 626, 629 in brain, stimulation by pyrogen 645 metabolism 402, 403 in peripheral nervous tissue, analgesia and Prostaglandin F 2. (PGF 2.) 607 anti-inflammatory modulator function 257 in peripheral nervous tissue, antipyretic co-factor requirement 396 activity and 646 generation 385,389 in peripheral nervous tissue, inhibition by generation, optimal conditions for 396,398 dipyrone 607 hyperthermic effect 625, 626, 629 in peripheral nervous tissue, inhibition by inactivation 410 paracetamol 607, 645 inflammatory mediator 573 in platelet 153, 178, 179, 401 metabolism 402,403,408,410 inhibition, analgesia and 604, 606, 607 peripheral level in man 402 inhibition, antipyretic activity and 645,646 platelet aggregation and 145, 153, 154 inhibition by aspirin 400, 401, 580, 604 turnover 402,403 inhibition by chlorpromazine 645 urinary metabolite excretion 402, 408 inhibition by dipyrone 607 Prostaglandin 15-hydroxy-dehydrogenase inhibition by fenamate 606 (PGDH) inhibition by haloperidol 645 distribution 408 inhibition by indomethacin 400, 401 inhibition by aspirin-like drug 413 inhibition by NSAID in rheumatoid joint inhibition by diuretic agent 414 334 inhibition by fatty acid 413 inhibition by sodium salicylate 400, 401 inhibition by PG analogue 412 inhibition by tricyclic anti-depressant 645 inhibition by PGB 412 inhibition, schizophrenia and 645 level 409 isoenzyme 400 PG catabolism and 406, 407 nomenclature 376 PG inactivation and 409,412,414 optimal conditions for 396-400 replacement 400,409 synthesis 400 synthesis 400,409 turnover rate 400 Prostaglandin intermediate, see also prosta• Prostanoic acid glandin endoperoxide nomenclature 377 generation 384, 386, 387 structure 378 structure 378 Protease Prostaglandin metabolite, see also specific collagen breakdown 482 metabolites inhibition by aprotinin 491 Subject Index 777

inhibitor, site clearance and 208 mediation by endogenous pyrogen 618, in platelet IX-granule 179 622 pro-inflammatory effect 298 mediation by PGE 637, 645, 648 scar formation and 210 pre-optic anterior hypothalamus and 620, Protein, denatured 621,645 chemotactic activity 117, 120--122 production 617 Proteinase inhibitor PG in CSF and 637,644,645,648,649 kinin formation inhibition 576 Protein-bound dye Rabbit aorta contracting substance (RCS), see vascular permeability and 582 also thromboxane A2 Protein kinase biosynthesis 390--392 in human PMN 306 pain production and 597,601 Protein-purified derivative of tuberculin (PPD) platelet aggregation and 153, 157, 188 delayed hypersensitivity and 247 Rabbit ear-chamber technique 474 Proteoglycan Rat paw oedema, see also carrageenin oedema biosynthesis, inhibition by hyaluronic acid adrenaline and 555 209 anti-proteasic agent and 482 in connective tissue 215 measurement of 582 structure 215 suppression by counter-irritation symthesis 215,216 527-529,531 Proteolytic enzyme, see also specific enzymes Reactive lysis 434,437,442 anti-proteasic agent and 482 Reaginic antibody, see also IgE injury and 14 immediate hypersensitivity and 346 kinin release and 469, 471 PCA and 182,183 scar formation and 210 Receptor, see specific receptors Prothrombin Receptor paralysis 151 Hageman factor and 471 Reflex reaction platelet coat and 139 measurement of pain and analgesia Protocollagen 220 588-590 Pseudoeffective response Regeneration, see tissue regeneration aspirin-like drug screening and 589 Repair, see tissue repair Bk-induced 16 Reserpine hyperalgesia and 597 rever and 633,646 Pulmonary fibrosis Resolution (of inflammation) 56-61 collagen synthesis and 212 Respiratory rate Pus 62,63 in fever 625,627,629 abscess formation and 63 Respiratory reflex anti-inflammatory property 523 pain and 591 definition 523 Reticulin Pyrexia, see fever in connective tissue 221 Pyridinium Reticuloendothelial system (RES) complement inhibitor 448 endogenous pyrogen production and 619, Pyrogen, see also endogenous pyrogen; 647 endotoxin; exogenous pyrogen; fever mononuclear phagocyte and 97 617-619 Retroperitoneal fibrosis 211 blood-brain barrier and 621, 646 drug-induced 225 cerebral ventricle injection 620, 621, 646 Reverse endocytosis 303 intravenous injection 620, 621 Rheumatic fever nomenclature 617 group A streptococci and 273 pre-optic anterior hypothalamus and 620, Rheumatoid arthritis (RA) 621,644-646 aspirin-like drug and 602 production by macrophage 76, 77 chronicity, defective homeostasis and 526 PG synthesis stimulation 644,646, 648, 649 chronicity, experimental arthritis and 254, site of action 620, 646--648 255,259 Pyrogen fever chronicity, lymphocyte reactivity and 554 antipyretic agent and 621,637,645,646, chronicity, PG suppression of lymphokine 648 and 554 778 Subject Index

Rheumatoid arthritis (RA) clinical 244 complement and 445, 446 complement and 243,444 endogenous antigen and 253 experimental 183,243,299,444 gastrin and 544 glomerular lesion in 184, 243, 444 hepatitis and 548 immune complex deposition in 184, 243, immune complex deposition in 285, 445, 444 446 immune complex deposition, histamin and immune complex phagocytosis in 303 360 immune process in 253 immune complex deposition, inhibition by immunostimulant and 253 histamine antagonist 243 kinin release and 498 immune complex deposition, inhibition by lysosomal enzyme release and 299,303 5-HT antagonist 243 platelet protease and 179 immune complex deposition, vascular pregnancy and 550,551 permeability and 184, 243, 360 serum, anti-inflammatory effect of 545 necrotizing arteritis, inhibition by C3 Rheumatoid factor depletion 444 in rheumatoid synovial fluid 445, 446, 498 necrotizing arteritis, inhibition by PMN kinin formation in rheumatoid joint and depletion 299, 444 498 nephritis 243 Ristocetin platelet and 184 platelet aggregation and 163, 166 prophylaxis, anti-histamine agent and 360 urticaria, mediator release and 365 Salicylaldoxine Shivering complement inhibitor 448, 449 fever and 623-629 Salicylate Shwartzman reaction PG biosynthesis inhibition 400, 401 complement alternative pathway and 232, Salmonella enteritis infection 236,237,245,246 monocyte production and 86 generalised 185,245-247 Scar tissue haemorrhage in 185,236,246,247 abnormality 223-225 human disease and 247 contraction 222 local 185, 232, 236, 237, 245, 246 formation 208-222 local, inhibition by C3 depletion 237, 246 formation, capillary formation in 210, 212 local, inhibition by indomethacin 185 formation, connective tissue formation in platelet and 185, 189 213-222 PMN and 236, 246 formation in absence of fibrin 211 specificity in 245 formation in presence of fibrin 210 Sialic acid formation stimulus 208 platelet aggregation and 145 hypertrophic 223, 224 Sialoglycoprotein keloid 223, 224 hypertrophic scar and 223 maturation 222, 223 Sieving mechanism Schizophrenia leucocyte migration and 54 febrile episode in 644, 645 Silicosis Scleroderma, see systemic sclerosis collagen synthesis and 212 Sclerosing peritonitis Site clearance, see also resolution drug-induced 225 tissue regeneration and 207, 208, 525 Serine Skin connective tissue proteoglycan and 215 blood flow and 580,581 procollagen and 218 Skin reaction, see also Arthus reaction, Serine esterase erythema, induration, Shwartzman activation by antigen 349 reaction d active site 426, 448 antibody-mediated immunity and 231 D active site 429,448 assay of mediator 256 mediator release and 349 cell-mediated immunity and 231 Serotonin, see 5-hydroxytryptamine complement-dependent 233-237,245 Serum sickness delayed hypersensitivity 231,232,247,248, chronic 184, 243 314,326 Subject Index 779

delayed hypersensitivity, histamine and Smooth muscle relaxation 13, 356, 360 histamine and 355 delayed hypersensitivity, 5-HT and 361 Snake venom delayed hypersensitivity, lymphokine and Bk release 464,465,469,471 326-328 kininase activity 472,473 immediate hypersensitivity 232, 234, 247, kininogen depletion 467 346 Sodium fever 643 immunological 231,232 Sodium meclofenamate lymphokine and 326--328 Bk-induced bronchoconstriction and 501 measurement of 256, 580, 581 Sodium pump 213 mechanism of 233-239 Sodium salicylate vasoactive amine and 356,360,361 anti-Bk effect 501 Slow reacting substance of anaphylaxis antipyretic effect 640,641,648 (SRS-A) 362-364 kinin release inhibition 501 anaphylaxis and 346 platelet PG synthetase and 153 antagonist 363 protein breakdown inhibition 482 bioassay 352 histamine synergism 364 Sodium urate crystals inactivation by arylsulphatase 302 Hageman factor activation 471 PG release 364 Somnolence receptor 363 fever and 623 release from basophil 345, 348, 363 Soybean trypsin inhibitor (SBTI) release from mast cell 345, 348, 362, 363 Bk inhibition 475,476,484, 502 release from neutrophil 345, 362, 363 carrageenin oedema inhibition 487, 488, release induced by calcium ionophore 576 A23187 351,363 plasma kallikrein inhibition 469, 470 release, inhibition by cAMP-active drug urate oedema inhibition 490 363 SRS/phag 302 release, inhibition by cytochalasin B 363 Staphylococcal infection release, kinetics of 351 suppuration and 62 release, mechanism of 363 Starling's hypothesis 33 release, stimulation by acetylcholine 350, Steroid, see corticosteroid 363 Storage pool disease (SPD) 167-171 smooth muscle effect 346, 363, 364 phospholipase defect in 170 synthesis 351,362,363 phospholipid defect in 170, 171 vascular effect 363, 364 platelet ADP and 159, 161, 168, 169 Slow reacting substance from cobra venom platelet aggregation, collagen induced and (SRS-C) 362 159,160,170 Small blood vessel platelet aggregation, LASS induced and fenestrated 31,33 170,171 fenestrated, gap formation in 42 platelet aggregation, PGHz induced and fenestrated, injury and 42 159,169, 189 fenestrated, pore system in 34 platelet aggregation, PGEz potentiation and permeability, direct vascular injury and 169, 171 45-48 platelet aggregation, ristocetin induced and permeability, gap formation and 34-42 163 permeability, histamine-type permeability platelet PG synthesis and 170 factor and 34-48 PG mechanism 169 permeability, normal 33, 34 Streptococcal infection sinusoid 33 group A, chronic inflammatory lesion and structure, normal 30-33 273 transport across wall 33, 34 group A, lysosomal enzyme release 273, Smooth muscle contraction 274 histamine and 12-14,346,353-355 group A, rheumatic fever and 273 5-HT and 346,360,361 suppuration and 62 SRS-A and 346, 363, 364 Stress trypsin and 15 kinin release and 469 780 Subject Index

Strontium Tetranorprostane lysozyme release from PMN and 298 PG turnover and 403 Structure-linked latency Theophylline lysosomal enzyme and 295 adjuvant arthritis suppression 554 Stupor cAMP elevation 350 fever and 623, 644 fever and 635 Sulphated dextran Thermal injury complement activator 432,447 Bk release and 484, 486 Suppressor cell histamine release in 484, 486 delayed hypersensitivity and 249, 250 hyperalgesia and 596 histamine receptor 359 kinin and 486 Suppuration 26,61,62 kinin-forming activity in 485 Suramin sodium (Antrypol) kininogen release in 485 complement inhibitor 448 leucocyte migration and 54 Swelling, see oedema lipoprotein molecule sieving in 54 Swine erysipelas 256 peptide urinary excretion and 485 Synovial A cell vascular permeability, capillary leakage and nomenclature 69 42,43,45,46,486 Synovial B cell vascular permeability, delayed-prolonged complement-sufficient anti-serum and 284 leakage and 42, 43, 46 Synovial fluid vascular permeability, direct vascular acute gout and 303, 490, 491 injury and 46, 486 acute synovitis and 498 vascular permeability, histamine and 486 Hageman factor in 491 vasoconstriction 28 kininase activity in 473 Thermic oedema kinin formation in 490, 491, 499 Bk release in 484 rheumatoid, complement abnormality in direct vascular injury and 486 446 formation, mechanism of 486 rheumatoid, haemolytic complement histamine and 484 activity in 445, 446 kinin and 486 rheumatoid, immune complex in 303, 446 kinin-forming activity in 485 rheumatoid, kinin content 498 kininogen release in 485 rheumatoid, lysosomal enzyme in 299,303, Thermoregulation 446 heat loss versus heat production 628, 629 rheumatoid, PG in 179 PG and 617, 623-629 rheumatoid, rheumatoid factor in 445,498 Thiobarbituric acid (TBA) thromboplastin antecedent in 491 malondialdehyde assay 388 urate deposition in 490,491,499 Thioglycollate Systemic sclerosis 224 macrophage stimulation, C-coated Systemic lupus erythematosus (SLE) 244 erythrocyte ingestion and 73 C4 deficiency and 427 macrophage stimulation, collagenase complement and 445, 446 secretion and 280,281 immune complex and 445 macrophage stimulation, elastase secretion and 281 macrophage stimulation, plasminogen Tachycardia activator secretion and 281,282 measurement of pain and analgesia 589 Threonine Tachyphylaxis 151 in collagen 218 Telopeptide in connective tissue proteoglycan 215 in collagen 217, 218 Thrombasthenia 166, 167 Temperature, see body temperature platelet aggregation defect and 144, 163, Testosterone 166 complement inhibitor 449 platelet shape change and 144 Tetrahydrofolate ristocetin and 163, 166 PG biosynthesis and 394--396 thrombasthenin level in 167 Tetrahydrofurfuryl nicotinate (THFN) Thrombasthenin counter-irritation and 532, 533 clot retraction and 164 Subject Index 781

platelet aggregation and 153, 167 Thrombogenic surface 142 platelet surface and 139 platelet shape change and 144 Thrombin Thromboplastin clotting activity 152, 164 antecedent in synovial fluid 491 clotting activity, inhibition by heparin 152, clotting mechanism and 162 162 Fleaujeac factor and 472 direct aggregating agent 152, 164 formation by Fletcher factor 472 direct aggregating agent, inhibition by Hageman factor and 472 heparin 152 prekallikrein and 472 direct aggregating agent, inhibition by produced by macrophage 76, 77 PGE 1 149 Thrombosis direct aggregating agent, mechanism of endoperoxide and 156 149, 153, 161 platelet aggregation and 188 fibrinogen activation 164 platelet collagenase and 179 haemostasis and 161, 164, 188 thromboxane synthetase and 158 Hageman factor and 471 Thromboxane A2 (TXA2) inflammation and 178 biosynthesis from arachidonic acid 382, platelet endoperoxide production 154,160, 385,392 164 biosynthesis from PGG2 146,154,157,390, platelet LASS production 154, 160 391,392 platelet PG biosynthesis 160, 177 biosynthesis from PGH2 154,157 platelet PG biosynthesis, inhibition by biosynthesis in platelet 154, 381, 390, 392 aspirin 153 haemostasis and 163 platelet PG biosynthesis, inhibition by half-life 157, 392, 578 heparin 186 in LASS 154 platelet PG biosynthesis, inhibition by in ReS 155, 157, 390, 392, 601 indomethacin 153 pain production and 601 platelet PG biosynthesis, SPD and 168, platelet aggregation and 154,157,158,163, 170 376,381,382,392 platelet release reaction induction, platelet aggregation, ADP and 146,157, mechanism of 160,161 159 platelet release reaction I 146,160,161,164 platelet cAMP elevation and 155 platelet release reaction I, inhibition by platelet 5-HT release 392 aspirin 146, 160 pro-inflammatory effect 375 platelet release reaction II 141, 160, 164 vasoconstriction 164 platelet release reaction II, chemotactic Thromboxane B2 (TXB2; PHD) activity and 176 biosynthesis from arachidonic acid 385 platelet release reaction II, phospholipase biosynthesis from PGG2 157,391 and 170,178 biosynthesis, inhibition by aspirin-like drug platelet release reaction II, SPD and 168, 391 170 biosynthesis, inhibition by indomethacin thrombosis and 188 175 Thrombocyte, see platelet biosynthesis in lung 391, 392 Thrombocytopaenia biosynthesis in platelet 157, 175,392 autoimmunity and 165 chemotactic activity 175 generalised Shwartzman reaction and 247 metabolism 410 haemostasis and 164, 165 pro-inflammatory effect 375 platelet phagocytosis and 187 prostaglandin MI and 393 platelet production defect and 165 Thromboxane synthetase produced by influenza virus 186 haemostasis and 158 produced by intravenous endotoxin 246 inhibition by imidazole 154 produced by PGH2 156 inhibitor, platelet aggregation and 157 Thrombogenicity thrombosis and 158 of kidney machine membrane 1::1-2 TXA2 synthesis in platelet 154 of non-siliconi sed glass 142 3H-thymidine labelling of teflon 142 lymphocyte transformation and 323 of vascular subendothelium 142 lymphokine bioassay and 323, 324, 330 782 Subject Index

3H-thymidine labelling Tolazaline mononuclear phagocyte kinetics and histamine Type 2 agonist 354 78-82 p-tosyl-l-arginine methyl ester (TAMe) mononuclear phagocyte kinetics in complement inhibitor 429, 448, 449 inflammation and 84-86,91 Tranexamic acid Tissue injury, see also specific types of injury complement inhibitor 449 blood flow and 28, 29 Transcobalamin II Bk release in 15 production by mononuclear phagocyte 77 direct vascular damage and 45-48 Transferrin histamine release in 12, 14, 15,483 production by mononuclear phagocyte 77 5-HT release in 15 Trasylol, see aprotinin hyperalgesia and 596 Trauma immediate pain and 588 histamine and 14,15 immunopathological events of, classification kininogen depletion 467,468 345 kinin release 482-495 initial response to 26, 28-48, 525 Tropocollagen kinin release in 483 argyrophilia and 221 leucocyte migration and 51-56 in collagen 216--218 leucocyte pavementing and 28,29,48-51 in reticulin 221 resolution of 56 Trypsin suppuration and 61 anti-histamine agent and 15 vascular permeability and 38,39,41,42, blood pressure effect 15 45-48 Bk release 16,464-467, 469, 471 vasoconstriction and 28, 29 Bk release, inhibition by SBTI 470 vasodilation and 28, 29 C3b receptor and 441 Tissue regeneration, see also cell proliferation carrageenin oedema and 489 206--208,226 crystalline, kallidin release 471 kinin and 498 Factor B activation 429 Tissue repair, see also scar formation 206 histamine release 15 homeostasis and 525 inhibition by aprotinin 470 kinin and 497,498 kininogen depletion 467, 489 of specialised tissue 225 prekallikrein activation 470, 489 Tissue tension smooth muscle effect 15 pain and 595 Tryptophan T lymphocyte in collagen 218 acid hydrolase release from macrophage and Tuberculin reaction 273,278 assay 247,258 antibody production, C3 and 442 cell-mediated immunity and 237, 247, 257 antigen stimulation of, macrophage and 77 cAMP level in 258 cell-mediated immunity, antigen recognition delayed hypersensitivity and 231,237,247, and 237 248 cell-mediated immunity, macrophage erythema in 247,248 activation and 77,252,277,278 exudate 258 cytolytic activity, inhibition by histamine histamine release 258 256--258,360 5-HT release 258 cytolytic activity, inhibition by 5-HT 362 induration in 247,248 effector cell in delayed hypersitivity 249 in pleural cavity 257,258 granuloma formation and 252 PG release 258 histamine Type 2 receptor 257,258 transfer 231,237 lymphokine secretion 77,252,332 Tuberculosis proliferation, Bk and 497 collagen synthesis in scar formation and proliferation in lymph node in delayed 212 hypersensitivity 238 Tubulin suppressor cell in delayed hypersensitivity in platelet microtubule 140 250 Turpentine injury tuberculin reaction transfer and 237 abscess formation and 62 Subject Index 783

endothelial damage and 41 Bk and 16,17,36,327,465,477,478,486, exudate, mediator in 15 574, 583 PMN migration and 62 capillary leakage 42--44, 46, 327, 486 vascular permeability and 15 carrageenin and 46,47 Turpentine pleurisy chemical injury and 43, 46 delayed-prolonged leakage and 46, 47 clostridial toxin and 43, 45, 46 exudate, cellulose sulphate and 488 counter-irritation and 530,631 kinin and 488 crushing injury and 42, 43 venular leakage and 46 delayed hypersensitivity skin reaction and TY A, see eicosatetraynoic acid 326 Typhoid vaccine delayed-prolonged leakage 41,46--48 pyrogen 620 direct vascular injury and 45--48, 486 Typosine endothelial gap formation and 34, 36, 38, in collagen 218 39,41,42,583 histamine and 36,54,327,478,486,574, 583, 584 Ulcer histamine receptor and 14 formation 62, 212 5-HT and 15,36,327,478,574 Ultrafiltration 5-HT antagonist and 243 of water 33 immune complex deposition and 243 of solute molecule 33 induration and 326 Ultra-violet light injury insulin and 552 delayed-prolonged leakage and 46 Jones-Mote reaction and 314 leucocyte pavementing and 49 kallidin and 477, 478 mediator release and 14 kallikrein and 15,477 Urate crystal kinin and 465,477,478,486 deposition in synovial fluid, acute gout and leucocyte migration and 54, 55 272,303,490 leukotaxine and 15 Hageman factor activation 490,491 local Shwartzman reaction and 236 inflammation, kinin and 490,491 LNPF and 327 phagocytosis, lysosomal enzyme release and lymphokine and 326, 327 272 lymphokine, PGE effect and 333 Urate oedema measurement of 574, 579, 582, 583 kinin and 490,491 measurement of, blood flow and 581, 583 Uridine diphosphate (UDP) proteoglycan synthesis and 215 measurement of, blue test 36, 59, 574, 582 Uridine diphosphate glucose (UDP-glucose) measurement of, labelled protein 36, 328, proteoglycan synthesis and 215 574,582,583 Uropod mechanism of, increased leakage 34,41,45, lymphocyte locomotion and 115 47,583,584 mechanism of, normal 33, 34 mepyramine and 326, 327 Vascular calibre, see vascular flow normal small vessel and 33, 34 Vascular endothelium, see endothelial cell permeability factor and 34-38, 45, 478 Vascular flow, see blood flow PMN kinin and 495 Vascular labelling PG and 327, 583 delayed-prolonged leakage and 46 pulmonary oedema and 42, 46 endothelial gap formation and 34, 36, 39 serum sickness and 243 lymphokine skin reaction and 327 thermal injury and 41--46,486 of capillaries 42, 327 turpentine injury and 41,46,47 permeability factor and 36, 38, 42 UV light injury and 46,531 vascular leakage pattern in injury and vascular labelling and 34,42,46,54,327, 42--45 531,583 Vascular permeability vasodilation and 29 acute inflammation and 26, 30, 38--48 venular leakage 38,42,45,46,327,486,547, anti-histamine agent and 243 583 bioassay 328 X-irradiation injury and 42, 43, 46 784 Subject Index

Vascular stasis leucocyte adhesion and 28, 48, 49 filtration and 582 leucocyte migration and 51,53 thermal injury and 486 leakage induced by permeability factor 36, tissue injury and 28, 29 38,42,45 Vascular subendothelium leakage induced by direct vascular leakage thrombogenicity 142, 163 45,46 Vasoactive amine, see also acetylcholine; resolution of inflammation and 57 histamine; 5-HT Vinblastine delayed hypersensitivity and 345, 356, 360, fibroblast adhesion and 111 361 leucocyte locomotion and 124 immune complex deposition and 345, 360 lysosomal enzyme release and 303, 304 pain production 593 Vocalisation pro-inflammatory effect 360 measurement of pain and analgesia 589, release in immediate hypersensitivity 345, 590 348, 360 von Willibrand's disease 163, 165, 166 release, ischaemia and 480 Vasoactive peptide, see also bradykinin; kinin Wheal and flare reaction mediator release 345 anaphylatoxin induced 351,440 pain production 593, 594 antigen induced 346 Vasoactive substance histamine and 13, 354 pain production 589,591-593 mast cell degranulation and 346,440 Vasoconstriction pruritis and 440 acute inflammation and 28, 29 reaginic antibody and 346 haemostasis and 164 Wound healing 5-HT induced 361 counter-irritation effect 528, 533 measurement of 580 Writhing reaction of skin, blanching and 580 Bk-induced 481 of skin, PO hyperthermia and 623-629 Xenon-133 Vasodilation, see also blood flow blood flow measurement and 581,583 acute inflammation and 28, 29, 571 X-irradiation injury Bk-induced 465,477 vascular permeability and 42, 43, 46 counter-irritation and 531,533 kinin induced 465,477 Yeast measurement of 580 complement inactivator 235 PO induced hypothermia and 627, 628 histamine release 487 resolution of inflammation and 56 5-HT release 487 Venom, see also cobra venom factor oedema, counter-irritation and 528 Bk release 16 pharmacological effect 14, 15 Zinc Venule, see also microcirculation; small blood lysozyme release from PMN and 298 vessel Zymosan blood flow in 27-29 Arthus reaction and 241 constriction after injury 27 complement alternative pathway and 235, dilation after injury 28, 29 283,432,447 fenestrated 31 monocyte production and 84, 86 gap formation in 34, 54 platelet aggregation and 161 Handbuch Volume 16: Part 2 der experimentellen Erzeugung von Krank- Ions alcalino-terreux II heitszustiinden durch das Pharmakologie/ Experiment/ Volume 18: Part 1 Handbook Experimental Production Histamine of Experimental of Diseases Part 2 Pharmacology Part 1 Anti-Histaminics Blut (In Vorbereitung) Part 2 Volume 19: Heffter-Heubner, Atemwege 5-Hydroxytryptamine New Series Part 3 and Related Heart and Circulation Indolealkylamines Part 4 Niere, Nierenbecken, Volume 20: Part 1 Blase Pharmacology PartS of Fluorides I Liver Part 2 Part 6 Pharmacology Schilddriise ofFluorides II (In Vorbereitung) Part 7 Volume 21: Volume 4: Zentralnervensystem Beryllium General Pharmacology Part 8 Stiitz- und Hartgewebe Volume 22: Part 1 Volume 10: Part 9 Die Gestagene I Infektionen I Part 2 Die Pharmakologie Die Gestagene II anorganischer Anionen Part 10 Infektionen II Volume 23: Volume 11: Part llA Infektionen III Lobelin Neurohypophysial und Lobeliaalkaloide Part lIB Hormones and Similar lrifektionen IV Po lip ep tides Volume 12: Part 12 Tumoren I Morphin und morphin- iihnlich wirkende Part l3 Tumoren II Verb in du ngen Part 14 Volume 14: Part 1 Tumoren III (In preparation) The Adrenocortical Hormones I Part 15 Kohlenhydratstoff- Part 2 wechsel, Fieber! The Adrenocortical Springer-Verlag Carbohydrate Hormones II Metabolism, Fever Berlin Part 3 The Adrenocortical Volume 17: Part 1 Heidelberg Hormones III Ions alcalino-terreux I New York Clinical Pharmacology Drug Receptor Interactions of Anti-Epileptic Drugs in Antimicrobial International Symposium Chemotherapy Workshop on the Determination of Anti• Epileptic Drugs in Body Auid II Symposium, Vienna, September 4-6,1974 (WODADIBOFII) held in Bethel, Bielefeld, Editors: I Drews, F.E. Hahn Germany, 24-25 May 1974 130 figures. VI, 314 pages. 1975 Editors: H. Schneider, D. Janz, (Topics in Infectious Diseases, Volume 1) C. Gardner-Thorpe, H. Meinardi, ISBN 3-211-81311-X AL.Sherwin Distribution rights for Japan: 129 figures, 89 tables. X, 370 pages. 1975 Kaigai Pub!. Ltd., Tokyo ISBN 3-540-06987-9 Contents: Receptor Hypothesis. - DNA as a Contents: Pharmacokinetics. - Pharma• Drug-Receptor. - Ribosomes as Drug• cology of Anti-Epileptic Drugs. - Various Receptors. - The Mode of Action of Chi or• Aspects (Varia). - Quality Control and Stan• amphenicol. - Microbial Enzyme as Drug• dardization. - Methodology of Determi• Receptors. nation. - Dictionary of Anti-Epileptic Drug Synonyms, Chemical Names and Nonpro• prietary Names Subject Index. Marihuana: Chemistry, Drug-Inactivating Enzymes Biochemistry, and and Antibiotic Resistance Cellular Effects 2nd International Symposium on Antibiotic Resistance, Castle of Smolenice, Editors: G.G. Nahas, W.D.M. Paton, Czechoslovakia, June 5-8, 1974 IE. IdanpiUin-HeikkiUi Editors: S. Mitsuhashi, L. Rosival, 151 figures, 2 colorplates, 118 tables. V Krcmery XIX, 556 pages. 1976 142 figures, 235 tables. XIII, 493 pages. 1975 ISBN 3-540-07554-2 Prague: Avicenum Czechoslovak Medical Press Contents: Marihuana Chemistry: Detection ISBN 3-540-07113-X and Identification of Cannabinoids and of Contents: Preface. - Introductory Lectures.• Their Metabolites. Kinetics and Biotransfor• Beta-Iactam Antibiotics and Beta-Iacta• mation. - Marihuana-Biochemical and mases. - Aminoglycoside Antibiotics and Cellular Effects: Effects on Isolated Cell Enzymes Involved in their Inactivation. - Systems. Interactions with Neurotrans• mitters. Organic and Developmental Effects. Resistance to other Drugs. - Antibiotic Re• sistance in Ps. aeruginosa. - Ecology, Epide• miology and Nosocomial Problems of Anti• biotic Resistance. F. Th. von Briicke, O. Homykiewicz, E.B. Sigg The Pharmacology of Psychotherapeutic Drugs Springer-Verlag VIII, 157 pages. 1969 Berlin (Heidelberg Science Library 8) (Deutsche Ausgabe s. Briicke/Homykie• Heidelberg wicz, Pharmakologie der Psychopharmaka) New York ISBN 3-540-90009-8