Stago 2011 Ed 2.Pub

1 Stago Newsletter Volume 2, Issue 2 August 2011 2 ISTH Internaonal Society on ISTH Kyoto Japan Thrombosis and Haemostasis INSIDE THIS ISSUE: The 23rd International Society on Thrombosis and Haemostasis met at Kyoto, Japan from July 23 -28, 2011. ISTH XXIII Kyoto 2 Kyoto ( 京都, Ky ōto, "Capital city") is a city in the central part of the is- Data backup options 3 land of Honsh ū, Japan. It has a population close to 1.5 million. Formerly the Training Needs? 3 imperial capital of Japan, it is now the capital of Kyoto Prefecture, as well as a major part of the architecture intact, it is one those bringing such items The CAT 4 Osaka-Kobe-Kyoto of the best preserved cities would be inclined to metropolitan area. in Japan. answer this truthfully? Luckily I had left my cobra Kyoto is renowned for its Kyoto has a humid sub- at home! Dabigatran 5 tropical climate. The abundance of delicious temperature was 32° Japanese foods and The ISTH meeting was “full Celsius (overnight 24°C) cuisine. The special on” with 8am starts for the Technical Information 6 and very humid. circumstances of Kyoto as sub committee meetings on a city away from the sea Saturday and Sunday Although ravaged by and home to many followed by the congress wars, fires, and Buddhist temples resulted program running Monday- Dates to Remember 7 earthquakes during its in the development of a Thursday. There were eleven centuries as the variety of vegetables approximately 500 posters imperial capital, Kyoto peculiar to the Kyoto area . on display each day was spared from much of together with a trade Educational Website 7 The key industry of Kyoto the destruction of World display comprising 49 is information technology War II. It was removed exhibitors. There were over and electronics: the city is from the atomic bomb 4500 delegates in total home to the headquarters target list (which it had attending the sub- of Nintendo, Intelligent headed) by the personal committees and general Systems, TOSE, OMRON, intervention of US congress. Secretary of War Henry L. Kyocera, Shimadzu Corp., Stimson, as Stimson Rohm, Horiba, Nidec Diagnostica Stago wanted to save this Corporation, Nichicon, GS conducted a number of cultural centre which he Yuasa and Murata lunch-time “Meet Our knew from his honeymoon Machinery and the Experts” sessions and a and later diplomatic visits. headquarters of Murata Satellite Symposium titled Manufacturing are located “Can we predict As a result, Kyoto is one in the suburbs of Kyoto in interventions in of the few Japanese cities the city of Nagaokaky ō. Haemostasis and that still has an abun- Sake brewing is Kyoto's Thrombosis.” A CD of dance of prewar buildings, traditional industry. these sessions will be such as the traditional available soon. townhouses known as The first interesting machiya. However, experience was the Diagnostica Stago was a modernization is customs declaration for Silver Sponsor for the ISTH continually breaking down passengers disembarking congress and generously the traditional Kyoto in in Japan. donated furniture and useful items from the favour of newer Am I bringing into the display stand to the architecture, such as the country Narcotic drugs, earthquake/tsunami Kyoto Station complex. Stimulants, Firearms such survivors of Japan. With its 2000 religious as pistols, machineguns, places- 1600 Buddhist bullets, dynamite, swords, Mark your calendars - the temples and 400 Shinto protected animals such as next ISTH is in shrines, as well as crocodiles, cobras, forged Amsterdam 2013. palaces, gardens and credit cards? Quite a (www.isth2013.org) collection and I wonder if 3 A new option for data backup • The use of external parallel or USB The STA Satellite is ready to add this port printers IMP box funconality with so ware version 422.05 (available September This means that you can back up your 2011). sengs, calibraons, and quality Floppy disks and parallel port printers are control for restoring onto the STA The price of the IMP box is only becoming more and more diﬃcult to Compact and STA Satellite at a later $900AUD (+GST) with free installaon. purchase and will one day become me, together with exporng your obsolete. Please contact us to arrange for a free paent ﬁles for use on a PC with instrument assessment. Currently the STA Compact and STA Microso Excel. Satellite analysers are not equipped with Email [email protected] If your STA Compact or STA Compact USB ports making it imposible for users to fax +61 3 9855 8999 or CT meets the minimum requirements connect USB keys or USB printers. phone 1800 4 78246 Australia the IMP box can be easily installed by Diagnosca Stago is pleased to announce your Stago representave. 0508 4 78246 New Zealand the availability of the IMP box for: Some older STA Compacts may need • an updated motherboard to allow this Bidireconal data transfer with a USB key funconality which would incur an addional cost. Do you have a need for training? Training is an integral key to the the training is as follows: easily deal with the more common smooth operation of any lab. Having errors and issues on the analyser. staff who are confident about using their equipment and analysers will help Bench-level training is suitable for make for a happy workplace. scientists / technicians / lab assistants who are performing However, many labs have regular staff routine tasks on the analysers, such turnover and it’s hard to make sure as running samples, loading that everyone is feeling adequately reagents, running QC’s, daily and trained with so many analysers in the weekly maintenance. laboratory. Often, even staff who have been in the lab for a long time feel that they would benefit from ‘refresher’ training. Training can be organized to be done by your local Applications Specialist at a time that suits you and your laboratory. To register your interest, please send us an email at [email protected] , or speak to your local Applications Specialist. More information is available at Key-operator training is a bit more in-depth, and is aimed at those our website: www.stago.com.au/en/ scientists / technicians who are products-services/stago-customer- looking after test setups, reagent lot services/ongoing-education/ number changes, calibrations, reactive maintenance and troubleshooting. The reactive maintenance and Stago would like to help you with this troubleshooting aspect can also be by offering both bench-level and very useful for scientists who are on key-operator training for your Stago shifts at times when there is no analysers. All training would be backup as it will give them the tailored to the laboratory and the confidence to be able to quickly and individual participants, but generally 4 Calibrated Automated Thrombogram (CAT) (reprinted due to popular demand) Diagnostica Stago has recently purchased Why measure thrombin? the Thrombinoscope™ company Thrombin is often seen as the end-product (Netherlands) and can now offer thrombin of the coagulation cascade and as such generation to our ANZ customers. responsible for the final step, the conversion of the soluble protein The Thrombogram describes the fibrinogen into the insoluble fibrin clot. concentration of thrombin in clotting plasma However, the coagulation cascade has so and is therefore a general physiologic many (nested) feedback loops and function test of the thrombotic haemostatic inhibitory pathways that are all directly or system. The CAT measures thrombotic as indirectly influenced by the developing well as bleeding tendency and can be used thrombin concentration that thrombin plays a central and pivotal role throughout the • to measure any genetic or acquired whole process. This makes the description thrombotic disorder such as AT deficiency of the concentration of thrombin in time an or use of oral contraceptives excellent tool to obtain a full picture of • to support the development of coagulability. The method uses the Thrombinoscope™ antithrombotic drugs such as antiplatelet software available from Diagnostica Stago * For Research Use Only. Not for use in drugs and direct inhibitors of thrombin. and is intended for research purposes only. diagnostic procedures. • to monitor the treatment of haemophilic disorders such as treatment More information can be found at with factor VIII, factor VIIa. Our patented technique is measured on a Thrombinograph™, a 96-well plate http://www.thrombinoscope.com/ • to monitor the treatment of thrombotic fluorimeter available from Diagnostica Stago Reagents and consumables are now ANZ (Thermo Scientific Fluoroskan), and disorders such as treatment with oral available from Diagnostica Stago ANZ. anticoagulant drugs (coumarin), any uses a thrombin calibrator that is needed to heparin (UFH, Fraxiparin), antiplatelet correct for inner filter effect, donor-to-donor drugs (Reopro, Clopidogrel) or any variability in colour of plasma, substrate Email [email protected] combination of drugs, to obtain a full picture depletion and instrumental differences. fax +61 3 9855 8999 or of the thrombotic tendency of patients at phone 1800 4 78246 Australia high risk for thrombosis or bleeding. 0508 4 78246 New Zealand Add your reagents to the 9696----wellwell plate… ...and watch the Thrombin generation on your screen 5 A New Oral Anticoagulant— Pradaxa® (dabigatran etexilate) Atrial Fibrillation (AF) is the most AF at the end of October, 2010. Kind thanks to our Diagnostica common type of cardiac arrhythmia Stago colleagues in the United Dabigatran (Pradaxa ®) is a member or abnormal heart rhythm involving States for this article. of a new class of drugs called Direct the upper two heart chambers. It is Thrombin Inhibitors (DTIs). DTIs are a named for the fibrillations or new class of anticoagulants that bind References: quivering of the heart muscles in the directly to thrombin and block its atria, instead of well controlled and 1.

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