Annual Report 2016 the UNIVERSITYTHE UNIVERSITY of TEXAS of TEXAS SYSTEM SYSTEM BOARD BOARD of REGENTS of REGENTS

Home , Hector Hall, James Avery (pilot boat), Tak Wah Mak

p53 genetics research genomics education prevention patient care patient survivorship clinical trials biochemistry neuroscience palliative care nanomedicine proton therapy global outreach nanotechnology molecular biology drug development genetic counseling cancer epigenetics integrative medicine translational research chromatin remodelers germline mutagenesis cancer care innovation cytogenetic technology stem cell transplantation molecular carcinogenesis experimental therapeutics gene expression research health disparities research clinical and translational research annual report 75 years75 of patient care research prevention education history cancer making

The University of Texas MD Anderson Cancer Center Annual Report 2016 THE UNIVERSITYTHE UNIVERSITY OF TEXAS OF TEXAS SYSTEM SYSTEM BOARD BOARD OF REGENTS OF REGENTS

® ® Paul L.Paul Foster, L. Foster, El Paso El Paso ChairmanChairman In honorIn honor of Charlesof Charles Aubrey Aubrey “Mickey” “Mickey” LeMaistre, LeMaistre, M.D. M.D. 7575 years years of of Making Making Cancer Cancer History History R. StevenR. Steven Hicks, Hicks, Austin Austin Vice chairmanVice chairman Feb.Feb. 10, 192410, 1924 – Jan. – Jan. 28, 201728, 2017 CharlesCharles LaMaistre, LaMaistre, M.D., M.D., was the was second the second full-time full-time president president of of JefferyJeffery D. Hildebrand, D. Hildebrand, Houston Houston Vice chairman Vice chairman The UniversityThe University of Texas of Texas MD AndersonMD Anderson Cancer Cancer Center, Center, serving serving ErnestErnest Aliseda, Aliseda, McAllen McAllen for 18for years, 18 years, from from 1978-1996. 1978-1996. Before Before taking taking the reins the reins from from DavidDavid J. Beck, J. Beck, Houston Houston R. LeeR. Clark, Lee Clark, M.D., M.D., LeMaistre LeMaistre spent spent seven seven years years as chancellor as chancellor of of The UniversityThe University of Texas of Texas System. System. KevinKevin Paul Eltife,Paul Eltife, Tyler Tyler MissionMission JanieceJaniece M. Longoria, M. Longoria, Houston Houston A pioneeringA pioneering figure figure in cancer in cancer prevention, prevention, LeMaistre LeMaistre served served on on the firstthe U.S. first Surgeon U.S. Surgeon General’s General’s Advisory Advisory Committee Committee on Smoking on Smoking The missionThe mission of The of UniversityThe University of Texas of Texas MD AndersonMD Anderson Cancer Cancer Sara MartinezSara Martinez Tucker, Tucker, Dallas Dallas JamesJames Conrad Conrad Weaver, Weaver, San Antonio San Antonio and Health,and Health, which which in 1964 in 1964issued issued its landmark its landmark report report identifying identifying CenterCenter is to iseliminate to eliminate cancer cancer in Texas, in Texas, the nation the nation and theand the cigarettescigarettes as a major as a major health health hazard. hazard. worldworld through through outstanding outstanding programs programs that integratethat integrate patient patient VarunVarun P. Joseph, P. Joseph, McKinney McKinney care,care, research research and prevention,and prevention, and throughand through education education for for StudentStudent regent regent UnderUnder his leadership, his leadership, MD Anderson’sMD Anderson’s prevention prevention program program undergraduateundergraduate and graduateand graduate students, students, trainees, trainees, FrancieFrancie A. Frederick A. Frederick becamebecame an international an international model model of research of research and service and service initiatives initiatives professionals,professionals, employees employees and theand public. the public. GeneralGeneral counsel counsel to the toBoard the Board of Regents of Regents that advancedthat advanced the science the science and application and application of cancer of cancer prevention prevention and populationand population sciences. sciences. He also He pioneered also pioneered multidisciplinary multidisciplinary care. care. THE UNIVERSITYTHE UNIVERSITY OF TEXAS OF TEXAS SYSTEM SYSTEM ADMINISTRATION ADMINISTRATION “Mickey’s“Mickey’s passing passing causes causes us to us pause to pause and rememberand remember his his VisionVision WilliamWilliam H. McRaven H. McRaven tremendoustremendous contributions contributions to the to growththe growth and scopeand scope of of ChancellorChancellor MD Anderson,”MD Anderson,” says Johnsays JohnMendelsohn, Mendelsohn, M.D., M.D., MD Anderson’sMD Anderson’s We shallWe shallbe the be premier the premier cancer cancer center center in the in world, the world, RaymondRaymond S. Greenberg, S. Greenberg, M.D., M.D., Ph.D Ph.D thirdthird full-time full-time president president and directorand director of the of Khalifa the Khalifa Institute Institute basedbased on the on excellence the excellence of our of people, our people, our our for Personalizedfor Personalized Cancer Cancer Therapy. Therapy. “MD “MDAnderson Anderson experienced experienced research-drivenresearch-driven patient patient care careand ourand science. our science. ExecutiveExecutive vice chancellor vice chancellor for Health for Health Affairs Affairs happyhappy and productive and productive years yearsunder under Mickey’s Mickey’s leadership, leadership, and I andwas I was fortunatefortunate to have to thehave privilege the privilege of building of building upon upon his legacy his legacy when when We areWe Making are Making Cancer Cancer History History®. ®. I succeededI succeeded him ashim president as president in 1996.” in 1996.” LOCATIONSLOCATIONS MD AndersonMD Anderson has Houston-area has Houston-area locations locations in the in Texas the TexasMedical Medical CoreCore values values Center,Center, Bay Area, Bay Area,Katy, SugarKaty, Sugar Land, Land, The Woodlands, The Woodlands, Bellaire Bellaire and and West HoustonWest Houston (diagnostic (diagnostic imaging), imaging), Memorial Memorial City (surgery) City (surgery) and The and The CaringCaring Woman’sWoman’s Hospital Hospital of Texas of Texas(gynecologic (gynecologic oncology). oncology). MD Anderson MD Anderson EDITOREDITOR By ourBy words our words and actions,and actions, we create we create a a physiciansphysicians also provide also provide cancer cancer care to care Harris to Harris County’s County’s underserved underserved AndyAndy Olin, Olin,program program director, director, Public Public Relations Relations caringcaring environment environment for everyone. for everyone. patientspatients at Lyndon at Lyndon B. Johnson B. Johnson Hospital. Hospital. In addition, In addition, there thereare two are two researchresearch campuses campuses in Bastrop in Bastrop County, County, Texas. Texas. The institution The institution also has also has developeddeveloped a network a network of national of national and international and international locations. locations. DESIGNERDESIGNER IntegrityIntegrity MichaelMichael Clarke Clarke We workWe work together together to merit to merit the trust the trust of of ® ® our colleaguesour colleagues and thoseand those we serve. we serve. MD ANDERSONMD ANDERSON CANCER CANCER NETWORK NETWORK www.mdanderson.org/cancernetworkwww.mdanderson.org/cancernetwork

DiscoveryDiscovery PARTNERPARTNER MEMBERS MEMBERS We embraceWe embrace creativity creativity and seekand seek new newknowledge. knowledge. • Banner• Banner MD Anderson MD Anderson Cancer Cancer Center Center (Gilbert, (Gilbert, Arizona) Arizona) ConquestConquest is published is published by the by MD the Anderson MD Anderson Cancer Cancer Center Center Board Board of Visitors of Visitors on behalfon behalf of MD of Anderson. MD Anderson. • MD• Anderson MD Anderson Cancer Cancer Center Center at Cooper at Cooper (Camden, (Camden, New Jersey)New Jersey) All correspondenceAll correspondence should should be addressed be addressed to the toPublic the Public Relations Relations Office Office – – • Summit• Summit Medical Medical Group Group MD Anderson MD Anderson Cancer Cancer Center Center (Berkeley (Berkeley Heights, Heights, New Jersey)New Jersey) Unit 700,Unit MD 700, Anderson MD Anderson Cancer Cancer Center, Center, 6900 Fannin6900 Fannin St., Houston, St., Houston, Texas Texas77030-3800, 77030-3800, • Baptist• Baptist MD Anderson MD Anderson Cancer Cancer Center Center (Jacksonville, (Jacksonville, Florida) Florida) 713-792-3457.713-792-3457. Email:Email: [email protected]. [email protected]. • Scripps• Scripps MD Anderson MD Anderson Cancer Cancer Center Center (San Diego,(San Diego, Calif.) Calif.) ArticlesArticles and photos and photos may be may reprinted be reprinted with permission. with permission. CERTIFIEDCERTIFIED MEMBERS MEMBERS • 15 health• 15 health systems systems and hospitals and hospitals in 12 statesin 12 states For informationFor information on supporting on supporting programs programs at MD at Anderson, MD Anderson, please please contact contact ASSOCIATEASSOCIATE MEMBERS MEMBERS PatrickPatrick Mulvey, Mulvey, vice president, vice president, Development, Development, 713-792-3450, 713-792-3450, or visit or the visit the myGivingmyGiving website website at www.mdanderson.org/WinterConquest. at www.mdanderson.org/WinterConquest. • Hospital• Hospital Israelita Israelita Albert Albert Einstein Einstein (São Paulo) (São Paulo) • MD• Anderson MD Anderson Cancer Cancer Center Center Madrid Madrid For informationFor information on patient on patient services services at MD at Anderson, MD Anderson, call call askMDAndersonaskMDAnderson at 877-632-6789, at 877-632-6789, or log oron log on •Vehbi•Vehbi Koc Foundation Koc Foundation American American Hospital Hospital (Istanbul) (Istanbul) to www.mdanderson.org/ask.to www.mdanderson.org/ask. AFFILIATEAFFILIATE MEMBERS MEMBERS • MD• Anderson MD Anderson Radiation Radiation Treatment Treatment Center Center at American at American Hospital Hospital (Istanbul) (Istanbul) © 2016© The 2016 University The University of Texas of MDTexas Anderson MD Anderson Cancer Cancer Center Center Not printedNot printed at state at expense. state expense. Printed Printed with soy-based with soy-based ink. ink. • Presbyterian• Presbyterian MD Anderson MD Anderson Radiation Radiation Treatment Treatment Center Center (Albuquerque, (Albuquerque, New Mexico)New Mexico) contents

2 A message from MD Anderson Cancer Center: 36 The Shared Governance Committee Opportunity and the evolution of cancer care 37 Administration 4 MD Anderson’s role in establishing the three pillars of modern cancer care 38 Faculty leadership

8 The history of Making Cancer History® 42 Our partners in Making Cancer History

12 75 years of progress: 67 Financial and statistical data A determined, patient effort

24 75 years of discovery: Pursuing the answer to cancer

Wheeler Williams’ “Wave of Life” was the centerpiece of the fountain located in front of MD Anderson’s Houston Main Building (formerly the Prudential Building) until 2012. The sculpture can still be seen outside the Dan L. Duncan Building. MD Anderson Annual Report

In its 75-year history, MD Anderson has experienced many changes on its way to becoming the premier cancer hospital in the nation.

From March 1, 1944, when The University of Texas’ M.D. Anderson Hospital Through strong strategic alliances, MD Anderson has created the nation’s leading for Cancer Research admitted its first patient, a 57-year-old man with lym- drug discovery infrastructure, which has led to new therapies and numerous phoma, to last year when The University of Texas MD Anderson Cancer Center clinical trials for patients failing the current standard of care. The program has served close to 135,000 patients, the institution has never slowed in its drive yielded major contracts with biopharmaceutical companies, enabled transfor- to advance cancer medicine through its patient care, research, prevention and mative agreements, catalyzed significant funding channels and created new education initiatives. companies that will advance our knowledge and provide long-term sources of Much of that success is due to the bold, brilliant and dedicated faculty mem- revenue to support our mission. You’ll read stories about such groundbreaking bers and staff who have never stopped learning, evolving and bringing new work in drug development in the pages of the annual report. approaches to the understanding and treatment of cancer. The MD Anderson We continue an unprecedented effort to more rapidly convert scientific discov- team is committed to defeating cancer because it’s one of humanity’s most eries into lifesaving advances through our Moon Shots Program™. Launched in important pursuits. 2012 with six Moon Shots™, the program has expanded to 13 multidisciplinary Cancer also evolves. It changes to become resistant to medication. It’s also deter- teams of cancer experts collaborating and innovating to stop close to 20 types mined, evasive, extremely complex and, in its way, intelligent. of the disease, which collectively account for 63% of cancer deaths annually. Of course, MD Anderson addresses all forms of cancer in its broad research But our intelligence and ability to adapt to change is far greater. And in evolution portfolio and vast clinical enterprise. and transition, there is opportunity. Through the Moon Shots’ APOLLO (Adaptive Patient-Oriented Longitudinal As an institution, MD Anderson is evolving and changing with the current Learning and Optimization) platform, high-quality biopsies and blood sam- health care environment. This time of transformation has made us stronger, ples are being collected from patients before, during and after treatment. Deep and in the past year we’ve continued to make significant progress toward our genomic and immune profile analysis of these longitudinally collected samples goal of ending cancer. provides a “moving picture” of cancer’s adaptability and enables our researchers to understand why some cancers respond to or resist certain treatments such as immunotherapy. APOLLO provides an opportunity to learn from every patient and have every patient benefit from research. It is true precision medicine. Over the next two years, such penetrating analysis will be conducted in thousands of tumor biopsies in more than 2,000 patients enrolled in 28 clinical trials for a number of cancers. The development of “liquid biopsies” holds the potential to replace tumor biopsies with blood-based profiling, providing a less invasive way to detect certain tumor mutations or changes in the immune cells that can point toward the best therapy for a specific person. A multi-year partnership recently was announced to make comprehensive liquid biopsy technology the standard of care in cancer treatment.

2 OPPORTUNITY AND THE EVOLUTION OF CANCER CARE

“Intelligence is the ability to adapt to change.” — Stephen Hawking

All of this massive molecular information will be integrated with clinical infor- His commitment to forward-looking cancer prevention is found in the DNA of mation from more than 250,000 patients and automatically imported into a big other institutional tobacco-control policies such as the EndTobacco program data warehouse dubbed the Translational Research Accelerator. This platform, and tobacco-free hiring policy. MD Anderson’s expertise and leadership in pre- which now houses the largest data set in the history of the field, empowers our vention set an important example for the entire University of Texas System and scholarly efforts with a never-before-seen capacity to more quickly and effi- helped pave the way for the system’s Eliminate Tobacco Use initiative. Because ciently bring about new insights and convert such discoveries into improved of that initiative, all 14 UT System institutions will be tobacco-free by June 1. outcomes for patients. This historic advance is one of our finest examples of In September, nearly 54 years to the day after President John F. Kennedy inspired Making Cancer History™. the nation to lead the world in innovation and space exploration with his “We Advances generated in MD Anderson’s labs, institutes and clinics, along with choose to go the moon” speech at Rice University, Vice President Joe Biden the partnerships and affiliations formed around the world through its Cancer shared a deeply personal message about his family’s battle with cancer and their Network® and other programs, have enabled the institution to influence the experience with the brilliant team of physicians and nurses at MD Anderson. cancer care of one-third of the world’s population today. Meanwhile, our cancer He also emphasized ideas critical to both the Moon Shots Program and the prevention efforts, such as research, education and risk assessment, will help national Cancer Moonshot initiative — increased collaboration, the importance reduce the burden of the disease for future generations. Speaking of prevention, of sharing data and the need for better access to clinical trials. 2016 marked 27 years since past president Charles “Mickey” LeMaistre made MD Anderson smoke-free. We were all saddened by Dr. LeMaistre’s passing in The vice president returned a few months later to join more than 2,000 January. He was a champion for cancer prevention and multidisciplinary care guests, including dignitaries from around the world such as former President who drove innovation and positioned MD Anderson to be the world’s most George H.W. Bush — a past Board of Visitors chair — at a stellar gala honor- impactful cancer center. ing MD Anderson’s 75th anniversary. During the celebration, the creation of the Beau Biden Chair for Brain Cancer Research was officially announced. It was part of an exciting week of events that raised close to $15 million to support our cancer-fighting efforts. It’s philanthropic support such as this that makes our mission possible. Without your commitment, the institution wouldn’t be able to test the limits with high-impact, high-reward research projects. We couldn’t take aim at major breakthroughs in patient care and hope to dramatically reduce mortality and suffering sooner through the Moon Shots Program and its platforms. Without you, we wouldn’t be the No. 1 cancer hospital in the nation and the most impactful cancer institution in the world as we look back over 75 years of Making Cancer History.

3 MD Anderson Annual Report

MD Anderson and the pillars of modern cancer treatment Three of the institution’s faculty members have played significant roles in the development of chemotherapy, targeted therapy and immunotherapy

hen the MD Anderson Cancer Center opened its doors to patients in 1944, the standard method for removing W tumors was surgery. Then came radiation treatment, its use accelerated by Drs. Gilbert Fletcher and Leonard Grimmett, pioneers in the field and MD Anderson faculty members, who designed the first affordable radiotherapy machine. Approved by the U.S. Atomic Commission in 1950, the cobalt-60 unit proved to be a more effective source of radiotherapy than existing machines and quickly became used around the world. The methods and machines that deliver radiation therapy have steadily improved since — and MD Anderson led the way. From the use of the betatron in the mid-1950s, to high-voltage linear accelerators (also developed by Fletcher) and the development of interventional radiology in the 1970s, to fractionated radiotherapy and intraoperative radiotherapy in the 1980s, in addition to many other breakthroughs, such as the combination of radiation and surgery or chemotherapy, MD Anderson was on the leading edge of what is known as the second pillar of cancer treatment. In the decades that followed, more effective, targeted and personalized approaches to treating cancer were developed and emerged as major pillars of modern cancer treatment. These include combination chemotherapy, in which multiple anticancer drugs are given simultaneously; targeted therapy, which uses drugs or other substances to more precisely identify and kill cancer cells without harming surrounding healthy tissue; and immunotherapy, an approach that enlists the body’s own immune system to fight cancer. As with radiotherapy, MD Anderson has been at the forefront of creating, improving and implementing these new treatments. Three of the institution’s trailblazers, in particular, are among the physicians and researchers throughout the world who have discovered new approaches that would forever change the way cancer care is delivered.

4 THE PILLARS OF MODERN CANCER TREATMENT

Chemotherapy Emil J Freireich, M.D., clinical professor of Leukemia

When Emil J Freireich, M.D., arrived at the National Cancer With bleeding as a cause of death essentially eliminated, Institute (NCI) in 1955 to head its leukemia program, the Freireich, who was assigned to the pediatric leukemia ward, disease was a virtual death sentence. Newly diagnosed patients turned his attention to curing children. soon died, usually from massive hemorrhaging or infections. Another difficult-to-treat disease, tuberculosis, recently had “Back then, the treatment for acute leukemia was very prim- been cured by administering three drugs simultaneously. itive,” says Freireich. “Chemotherapy drugs had recently When given separately, they didn’t work. become available, but patients died before the drugs had a Freireich believed this approach might work for leukemia as chance to work.” well. So he began combining chemotherapy drugs instead of To buy time for patients while the giving them one at a time. drugs killed cancer cells, Freireich First he administered two of the highly toxic drugs, then Inspired by the success knew he needed to halt the non- three. With each addition, children became sicker from the of using three drugs at stop bleeding that is the hallmark drugs’ side effects. Some almost died. When he upped the the same time to cure of leukemia. tuberculosis, Emil J ante to four drugs in a 1961 trial, an outcry arose from the Freireich, M.D., began He conducted studies that revealed medical establishment. Freireich’s toxic cocktail would kill combining chemotherapy patients’ bleeding was caused by the children, they said. Instead, 90% went into remission drugs to treat childhood an insufficient number of plate- immediately. lets — the tiny, colorless discs that leukemia. Once children were in remission, Freireich continued their circulate in blood and promote four-drug regimen for a full year to kill any residual cancer clotting. Further studies by Freireich cells. That exact strategy, called early intensification, is still showed that platelets needed to be obtained from freshly used today, and the cure rate for childhood leukemia is 92%. donated blood. “The disease recurs in some patients, but not many,” Freireich “Platelets in blood only last 48 hours,” he explains. “At the says. “Most are cured for the duration of their lifetime. Their time, blood bank protocol specified that the oldest blood on survival rates are the same as for people who hadn’t had the shelf be used first. So the platelets patients were getting leukemia.” didn’t work — they had already expired.” He next applied this approach to Hodgkin’s disease, also These findings inspired Freireich to help invent a machine rendering it curable in many cases. to separate blood into three components: plasma, red blood cells and white blood cells. Separating the blood into parts let Combination chemotherapy is now a standard treatment for patients get only the specific part of the blood they needed to a wide range of cancers, including breast, bone and testicular, combat infections, control hemorrhaging and help manage and has been credited with saving millions of lives worldwide. other complications of cancer and its treatment. Later models In 1965, Freireich and his NCI friend and collaborator Tom are used around the world today. Frei, M.D., were recruited by MD Anderson to launch a chemotherapy program. Until then, the cancer center had treated patients with surgery and radiation. The two doctors formed the Department of Developmental Therapeutics and hired brilliant young scientists who developed drug combinations that cured various cancers based on the same methods used to treat childhood leukemia. Today, nearly all successful chemotherapy regimens use this approach of administering multiple drugs simultaneously.

5 MD Anderson Annual Report

Targeted Therapy John Mendelsohn, M.D., professor of Genomic Medicine and director of the Sheikh Khalifa Bin Zayed Al Nahyan Institute for Personalized Cancer Therapy

While the 1970s and ’80s continued to see progress arising the EGF receptors and turning them off by preventing them from innovations in surgery, radiation and chemotherapy, as from binding to EGF. well as bone marrow transplantation, the late 1990s ushered Mendelsohn likens the process to “putting chewing gum in a in the era of targeted therapies — drugs and other agents like car’s ignition to prevent the key from turning on the engine.” antibodies that interfere with specific molecules found inside of and on the surface of cancer cells, effectively blocking the For this discovery, he and Sato are widely acknowledged as disease’s growth. the physician-scientists who shaped the landscape for today’s research into targeted therapies. Unlike chemotherapy’s random blast, which kills both healthy and cancerous cells, targeted therapies, also called Mendelsohn says he had the privilege Targeted therapies usually precision medicine, act like a sniper shot aimed precisely at of benefiting from the influence of a are not cures, but they the growth signal in malignant tumors. Targeted therapies number of physicians and mentors stop tumors from growing usually are not cures, but they stop tumors from growing and early in his career, including James D. and spreading, which spreading, which is significant because it’s a tumor’s ability to Watson, Ph.D., who won the Nobel Prize is significant, because reproduce and metastasize throughout the body that makes in Medicine for identifying the structure it’s a tumor’s ability to it deadly. By stopping cancer growth, targeted therapies often of DNA. While working toward his reproduce and metastasize bachelor’s degree at Harvard College, work in combination with other treatments, such as surgery, throughout the body that Mendelsohn became the first under- makes it deadly. chemotherapy or radiation, to effectively remove, shrink or graduate student in Watson’s lab. destroy tumors. “The field of molecular biology was in its infancy, ready to The advent of targeted therapy saw the creation of precision explode,” he recalls. “I was introduced into rigorous exper- drugs by scientists worldwide, including rituximab (Rituxan), imental science and new technologies in a superb scientific which targets certain forms of lymphoma and leukemia; environment.” imatinib (Gleevec), for the treatment of certain leukemias, skin cancers, and stomach and digestive system cancers; The past several decades have witnessed a quantum leap in and trastuzumab (Herceptin), which targets the product of understanding the genetic and molecular causes of cancer, a gene in breast cancers. Mendelsohn says, and the pace of drug discoveries is increas- ing as more abnormal molecular signals and pathways are One of the very first targeted drugs, cetuximab (Erbitux) was discovered. born from research conducted by John Mendelsohn, M.D., and Gordon Sato, Ph.D., while they were faculty members at “It’s an exhilarating time to be part of the growing rise of the University of California, San Diego. Mendelsohn would precision medicine,” he says. later become president of MD Anderson, which under his Mendelsohn stepped down in 2011 after 15 years of leader- leadership in the early 2000s, became the leading clinical ship as MD Anderson’s president. He remains on faculty as trial site for smart drugs that target cancers at the molecular a professor of Genomic Medicine and director of the Sheikh level. Today, Erbitux is used for colon, pancreatic, head and Khalifa Bin Zayed Al Nahyan Institute for Personalized neck, and lung cancers. Cancer Therapy. The institute focuses on targeting the abnor- Simply put, here’s how it works: Many cancer cells have mal genes and products of genes that cause cancer, tailoring receptors called epidermal growth factor receptors (EGFR) specific treatments for individual patients. on their surfaces. A protein produced naturally in the body “I remain committed to doing what I can to translate the called epidermal growth factor (EGF) attaches to these many new scientific discoveries about cancer into better receptors. This triggers the cancer cell to grow and divide treatments that ease the burden of cancer on our patients into more cancer cells. Erbitux works by attaching itself to today and in future generations.”

6 THE PILLARS OF MODERN CANCER TREATMENT

Immunotherapy Jim Allison, Ph.D., chair of Immunology

For more than 100 years, scientists and physicians found tan- Treating T cells, not cancer talizing hints that our immune system is capable of detecting, Allison’s key insight was to block the brake with an antibody, destroying, remembering and permanently stifling cancer, freeing T cells to attack cancer. as it does viral or bacterial infections. “I didn’t set out in my research to treat cancer, but it was In 1891, surgeon William Coley began treating patients with in the back of my mind,” Allison says. “My mother died of a mixture of bacteria and bacterial fragments called Coley’s lymphoma when I was 11, and she suffered greatly from Toxins. Coley cured a few patients, but the treatment failed the effects of chemotherapy and radiation. An uncle died of for most and was completely unpredictable. By the early prostate cancer, and another of lung cancer.” 1900s, it was superseded by radiation, a new therapy with more consistent results. His drug treated the immune system, not the cancer, with powerful results in mice. German scientist and 1908 Nobel Over 3,500 patients have Laureate Paul Ehrlich, M.D., pro- Given the past failures of immune-based therapies, it took been enrolled in more than posed that the immune system Allison years to persuade a small biotech company to develop 165 immunotherapy clinical routinely suppresses tumor forma- the treatment for people. Ipilimumab, a drug developed from trials at MD Anderson. tion, a hotly contested hypothesis his research, became the first ever to extend the survival of for decades. patients with late-stage melanoma. A trickle of immune-related cancer therapies emerged. These His efforts cleared the way, both scientifically and commer- included the tuberculosis vaccine Bacillus Calmette-Guérin cially, for a new class of drugs. for non-invasive bladder cancer; an immune signaling Today, immune checkpoint blockade drugs are approved for molecule, interleukin-2, a harsh drug that helps a small late-stage lung, kidney, bladder, head and neck cancers, mel- percentage of melanoma patients; and a host of therapeutic anoma and Hodgkin lymphoma; with 15 to 30% of patients vaccines designed to stimulate an immune attack on cancer, responding. Allison’s drug, known commercially as Yervoy, which largely failed. has been in the clinic the longest, and research shows that approximately 22% of late-stage patients live for 10 years or Basic science breaks through longer — previously unprecedented results. A combination of curiosity-driven basic science research and Hundreds of clinical trials are expanding the reach of these an intimate familiarity with the personal tragedy of cancer drugs to other cancers and to earlier stages of disease. The helped Jim Allison, Ph.D., chair of Immunology, lay the answer to higher response rates and longer survival in more foundation for immunotherapy to emerge as the next pillar cancers, Allison says, is more science. of cancer treatment. As executive director of the immunotherapy platform of “I’ve always wanted to know how things work,” Allison says. MD Anderson’s Moon Shots Program™, Allison and col- “I became fascinated with the immune system as an under- leagues seek to identify new checkpoints to block, and new graduate, and eventually settled on studying T cells — these immune-stimulating molecules to activate and protect. remarkable cells that travel all over our bodies detecting and Examination of tumors before, during and after treatment destroying infections and abnormal cells, usually without has provided a scientific basis for drug combinations that harming normal cells.” might make immunotherapy work for prostate, colorectal As a young scientist, he immersed himself and his lab and other common cancers. in understanding the basic biology of T cells, first at And scientists have developed and are testing new therapies MD Anderson’s Science Park-Research Division in Smithville, that expand a patient’s own T cells in the lab or genetically Texas, and later at the University of California, Berkeley. modify them to attack specific targets before infusing them Allison helped identify a brake on the immune system, an back into patients. off-switch on T cells that for decades eluded investigators “Cancer immunotherapy is still in its early stages, but as trying to develop immune treatments. science progresses and clinical research grows, we’ll be able to talk about curing or greatly extending the lives of more cancer patients,” Allison says.

7 MD Anderson Annual Report

The history of making cancer history

t MD Anderson, everything revolves around patients, which is why it’s been ranked the nation’s top cancer hospital for nine 1941 A of the past 10 years. The institution has changed the world by The Texas Legislature votes to establish a turning research discoveries into life-saving care. Through its Moon state cancer hospital devoted to research and treatment. Shots Program™, these breakthroughs are being converted into clinical It’s placed under the jurisdiction of The University of Texas and its Board of Regents. advances more quickly than ever. Here are some of the highlights of what’s been accomplished over the past 75 years.

Physician R. Lee Clark, M.D., is appointed director and surgeon-in-chief. Clark immediately begins planning for permanent facilities.

1944 1946 1949 1950 M. D. Anderson Hospital for English physicist Leonard Grimmett, M.D. The U.S. Atomic Energy Commission Cancer Research is dedicated (bottom row, middle) arrives to work with approves Fletcher (second from left) and on February 17. On March 1, French-born physician Gilbert Fletcher, Grimmett’s original concept for the cobalt-60 the hospital, with fewer than M.D. Within months, they design a 1,000- unit. The machines deliver more effective, Curie cobalt-60 unit that will revolutionize less expensive radiation therapy and will 25 full-time employees, radiation therapy. eventually be used in nearly all of the takes in its first patient in a world’s hospitals. makeshift clinic at the Baker Estate. Admission is limited to indigent Texas residents without treatment facilities 1954 in their home communities, Forty-six patients from the though staff seek to make the Baker Estate are moved to hospital available to all Texans the new hospital in the Texas as quickly as possible. Medical Center. The 320,000 square-foot facility has 310 beds and is hailed as the most modern hospital in the nation.

8 THE HISTORY OF MAKING CANCER HISTORY

1967 The effects of hyperbaric 1960 oxygen therapy are tested on mice in the Department of A landmark study shows Experimental Radiotherapy. the effectiveness of mammography in detecting early breast cancers, paving the way for routine use of screening mammograms for women throughout the world.

The nation’s first germ-free plastic isolation units, called “Life Islands,” open for patients whose immune systems have been impaired by chemotherapy.

1958 196 4 1966 1968 1971 Emil J Freireich, M.D., designs the Wataru Sutow, M.D., greatly Microscopes such The National Cancer Institute (NCI) President Richard Nixon continuous-flow blood cell separator, improves survival rates for as this one were selects MD Anderson to become declares war on cancer by which greatly improves the process of children with Wilms’ tumor by used in the study the headquarters for a new program signing the National Cancer removing white blood cells from donor introducing the first successful of tumor virology, designed to make sure radiation Act, which appropriates a field that has led blood. The technique will later be chemotherapy to treat the to breakthrough dosimetry is uniform at all institutions millions of dollars to cancer adapted for both immunotherapy and inoperable kidney cancer. discoveries and a participating in NCI-cooperative research. The majority of bone marrow transplantation. Soon better understanding clinical trials. The Radiological Physics funds are designated for NCI- after, Freireich, a legendary figure in of cancer over Center establishes MD Anderson as a recognized “comprehensive oncology, joins MD Anderson. the years. These primary radiation physics resource for cancer centers,” of which discoveries have hospitals throughout the U.S. MD Anderson is one of resulted in improved the first three. treatments and ways to prevent many forms of the disease.

9 MD Anderson Annual Report

1976 MD Anderson demonstrates in clinical studies that “lumpectomy” followed by radiation therapy for breast cancer can be as effective as radical surgical 1981 mastectomy. The new procedure With a $2.8 million grant becomes a worldwide standard and from the National Cancer replaces the highly invasive and widely Institute, installation practiced radical mastectomy. of the country’s first medical cyclotron begins.

1973 1985 1986 19 8 8 Isaiah Fidler, D.V.M, Ph.D., finds that Gabriel Lopez-Berestein, M.D., develops an A team directed by Waun Ki Hong, MD Anderson becomes cancerous tumors are composed of antifungal, liposomal-encapsulated agent for M.D., proves the effectiveness of the first hospital in the many distinct cell types. Fidler proposes the treatment of potentially life-threatening chemoprevention by showing that country to open an operating and confirms that metastasis is a non- systemic fungal infections, common synthetic vitamin A can significantly room that includes a random event unique to specific cell among patients with reduced immunity reduce the incidence of second linear accelerator to treat types within a tumor environment, a due to chemotherapy. Lopez-Berestein’s primary tumors in head and neck tumors with electron beam breakthrough that will transform the development is an incredible advancement, cancer patients. radiotherapy during surgery. study of tumors, drug development and as regular antibiotics have proven too toxic targeted cancer treatments. He will for cancer patients to withstand. bring his research to MD Anderson and continue on as one of the foremost experts on cancer metastasis. 1978 MD Anderson physicians collaborate with the IBM Corporation to develop An organic vapor and introduce a simplified blood- chromatograph such cell separator for practical use as this one was used in small hospitals. The machine to check the parts per million of gas in areas revolutionizes the availability and such as laboratories, use of blood component therapy where potentially throughout the U.S. dangerous chemicals were used.

10 THE HISTORY OF MAKING CANCER HISTORY

1995 2009 The Texas Legislature approves Senate Bill 192, An experimental drug developed at MD Anderson is able to starve allowing patients to refer themselves to human neuroblastoma cells by shutting down their energy source. MD Anderson. In addition to self-referral, the The drug, 3-BrOP, is found to reduce tumor growth by more than 75% as a single agent. Pre-clinically, this drug has proven effective measure helps the institution become more against other cancers, including glioblastoma, colon cancer, competitive in the area of managed care. lymphoma and acute leukemia.

19 92 1994 2005 2006 2013 The National Institutes of Health Scientists at MD Anderson MD Anderson pioneers the first A team of MD Anderson researchers Juan Fueyo, M.D., and Candelaria gives MD Anderson approval to invent the concept of varying pencil beam scanning capability demonstrates the effectiveness Gomez-Manzano, M.D., create conduct gene therapy trials for the intensity of radiation beams, in the nation’s most advanced of two new drugs, dasatinib and an experimental therapy that patients with lung cancer. leading to the revolutionary proton therapy facility. The precise nilotinib, in Gleevec-resistant genetically modifies the adenovirus MD Anderson doctors use gene development of intensity- treatment builds upon proton chronic myelocytic leukemia, that causes the common cold, therapy for ovarian and breast modulated radiation therapy, in therapy, which uses protons to leading to FDA approval. transforming it into a cancer-seeking cancer patients, and within six which radiation doses are tightly deliver radiation directly to a missile that attacks brain tumors. years, the techniques will be conformed in three dimensions to tumor, leaving surrounding healthy applied to multiple types of cancer. the shape of the tumor. tissue unharmed. 2012 Jim Allison, Ph.D., a pioneer in the innovative field of immunotherapy, joins MD Anderson to lead critical immunology research and work with the Moon Shots Program™. Allison’s groundbreaking discoveries have led 2000 the way for oncologists to unleash the immune system to attack cancer. The institution’s first international partnership, MD Anderson Madrid, opens, giving patients access to many MD Anderson clinical trials closer to home, and allowing specialists at each center to exchange expertise in clinical care and basic science research.

11 MD Anderson Annual Report

During a routine checkup, Kylie Delaney’s pediatrician noticed an unusual mass in her middle ear that turned out to be an extremely rare bone tumor called an osteoblastoma. Her parents brought the 8-year-old to MD Anderson, whose cancer experts are renown for treating rare and uncommon forms of the disease. Surgeons Paul Gidley, M.D., and Franco DeMonte, M.D., successfully removed the entire tumor. Read Kylie’s story on Page 21. photo by Wyatt McSpadden

12 75 YEARS OF PROGRESS

For 75 years, one determined, patient effort to end cancer

Seventy-five years. Think about it. That’s 900 months. 27,375 days. 657,000 hours. That’s a lot of time committed to treating, researching, studying and learning about one thing: cancer. Since 1941, MD Anderson has attracted many of the brightest minds in medicine to Houston, where they’ve changed the world and the way cancer is treated through innovation, creativity and breakthroughs. They’ve developed and put into practice leading-edge technologies. Their commitment has resulted in improved outcomes and a steady rise in survival rates for cancer patients around the world. That tradition of discovery continues in 2017, and will carry the institution through the years to come as the advances of today lay the foundation for the cancer care of tomorrow. And care is the operative word, because in addition to discovery and integ- rity, it’s one of the three keystones of what has been — and will be — built at MD Anderson.

immune checkpoint blockade monoclonal antibodiesvirotherapy Chimeric Antigencombination Receptor chemotherapy(CAR) T cell therapyprecision medicinetargeted therapyproton therapy genetic screeningearly detection andstem prevention cell transplant radiation therapypersonalized cancer care chemoprevention

13 MD Anderson Annual Report

Rosa Hwang, M.D., associate professor of Breast Surgical Oncology photo by Wyatt McSpadden

14 75 YEARS OF PROGRESS

Treatment puts the freeze on breast cancer

By Ronda Wendler

hen Jo Ann West learned she had early-stage breast cancer, her doctor Boosting an immune response suggested an inventive new treatment that involves no major surgery, Besides the advantages of no pain, no downtime and no no chemotherapy and no radiation. scarring, there’s another potential perk with this technique: W It appears to stimulate an anti-cancer immune response, The simple outpatient procedure, called cryoablation, “deep- The regimen includes a 6- to 8-minute freeze at temperatures Hwang says. freezes” tumors, killing cancer cells on the spot. Recovery 40 degrees below zero or colder, followed by a 10-minute “We think that cryoablation causes tumor cells to burst and is measured in minutes instead of months. thaw, then another 6- to 8-minute freeze. Doctors then release their cancer genetic material into the body,” Hwang remove the probe, place a Band-Aid over the tiny incision, “It sounded like science fiction to me, but I thought, ‘why explains. “The patient’s immune system ramps up to attack and the patient goes home. not try it?’” says West, 79. “It sure beat the alternatives.” this flood of cancer.” The entire procedure takes less than half an hour. There’s The retired elementary school teacher said yes, and was Immune cells, researchers believe, will attack the primary no hospitalization, no sedation, no scarring and no pain. placed in a clinical trial designed to determine cryoabla- cancer, as well as cancer cells that have spread to other areas tion’s effectiveness. “I’ve prescribed pain pills but no one fills their prescriptions,” in the body. And because the immune system “remembers” Hwang says. “They simply don’t need to.” the cancer cells, it will annihilate any cancer that attempts The study took place at 19 cancer centers across the country, to recur. including MD Anderson. Recovery is instantaneous, she says. Some women have even walked out of the hospital and gone shopping or to Researchers have confirmed this revved-up immune “Cryoablation has been used for years to successfully treat a restaurant. response in mice, and they’re preparing to test it on people. benign breast tumors called fibroadenomas, as well as other cancers such as prostate and kidney,” says Rosa Hwang, M.D., After cryoablation, patients are seen for follow-ups, includ- “Only time and further research will uncover the full benefits associate professor of Breast Surgical Oncology and princi- ing mammograms, every six months for the first five years, of cryoablation for breast cancer,” Hwang says. “But right pal investigator of MD Anderson’s trial site. “It worked for then annually after that. Some may be followed more fre- now the potential looks promising.” other cancers, so we thought, ‘let’s try it on breast cancer.’” quently, depending on their individual health. How it works Promising results To perform the procedure, doctors use ultrasound imaging In the multicenter trial, cryoablation was performed on to guide a thin, needle-like device through the skin and into women with early-stage breast cancer whose tumors were the breast tumor, where it blasts liquid nitrogen to freeze 2 centimeters or smaller. and destroy the cancerous tissue. “Before and after” MRI images were taken so doctors could “Everyone in the treatment room, including the patient, examine each patient’s tumor to confirm it had been fully watches the action in real time on the ultrasound screen,” frozen. Hwang says. “An ice ball forms around the tumor and freezes Several weeks after cryoablation, the women’s now-dead it from the inside out. It’s visually impressive.” tumors were surgically removed and examined so doctors could confirm that all cancer cells were killed. In a multicenter clinical trial of cryoablation on women with early-stage breast cancer whose The results: At all 19 cancer centers, cryoablation killed tumors were 2 centimeters or smaller, the treatment 92% of cancers — meaning no remaining cancer was found killed 92% of cancers and 100% of tumors smaller — and 100% of tumors smaller than 1 centimeter. In the than 1 centimeter. In the MD Anderson trial, 100% MD Anderson trial, 100% of all tumors were killed. of all tumors were killed. “This is a huge advance for women,” Hwang says. “I think it could be the wave of the future.” “It sounded like science fiction to me, but I thought, ‘why not try it?’” says breast cancer survivor Jo Ann West of her initial reaction to cryoablation therapy. photo by Wyatt McSpadden

15 MD Anderson Annual Report

Study draws attention to what could be a costly trend in treatment

By Laura Sussman

hen Caroline Wetherall of Kentucky was diagnosed with early-stage breast $22,000 more expensive than lumpectomy followed by cancer at age 43, her doctors recommended a complete mastectomy. radiation. In the older population, lumpectomy with W brachytherapy was most expensive, at approximately Stunned by her diagnosis and her doctors’ aggressive These therapies offer equal survival profiles, explains $38,000. Mastectomy and reconstruction was around recommendation, Wetherall returned to her hometown Smith, an associate professor of Radiation Oncology, but $36,000, while lumpectomy with radiation was $34,000. of Houston seeking a second opinion. differ greatly in terms of what patients endure. Smith says he found the results shocking, especially the There, she met radiation oncologist Benjamin Smith, “We haven’t had a nuanced understanding of the pros and fact that, on average, insurance companies pay roughly M.D., and was immediately relieved to learn her treatment cons of these different treatment approaches,” says Smith. $10,000 in the two years following diagnosis to deal with could be limited to lumpectomy — surgery in which only complications experienced by patients who chose mas- That is, until now. the tumor and some surrounding tissue is removed — and tectomy and reconstruction. three weeks of radiation. In a study published in the Journal of the National Cancer “For the first time, we show that while the patient is under- Institute, Smith and colleagues found that mastectomy “Personally, I couldn’t imagine having both of my breasts going more surgery, she is also taking on a considerable followed by reconstruction had the highest rate of com- unnecessarily removed at such a young age if I didn’t have amount of risk with regard to what could happen,” Smith plications and complication-related costs for women with to,” Wetherall says. says. “If the patient can have a lumpectomy and radiation, early-stage disease, regardless of their age. it may be a smoother course than going through a mas- Women with early-stage breast cancer have a number “There’s been little data to understand the differences tectomy, reconstruction and, potentially, other surgeries.” of treatment options, including lumpectomy plus whole in complications, and even less data to understand the breast radiation, lumpectomy plus brachytherapy, in difference in cost between those options,” which tiny radioactive seeds are implanted to destroy says Smith. “Quantifying this information cancer cells, mastectomy alone, mastectomy plus recon- In a study published in the Journal of the National Cancer Institute, is helpful both for patients making treat- struction, and, in older women, lumpectomy alone. Benjamin Smith, M.D., and colleagues found that mastectomy ment decisions and for payers.” followed by reconstruction had the highest rate of complications The rate of mastectomy plus reconstruction and complication-related costs for women with early-stage breast has continued to rise across the country cancer, regardless of their age. over the past decade as reconstruction has become more widely accessible. This study is the first to quantify the harm associated with this trend, He stresses decisions shouldn’t be based solely on cost, Smith points out. but instead on what’s personally best for each patient. In conducting the study, researchers analyzed data from “Many women with early-stage breast cancer differ in more than 100,000 early-stage breast cancer patients who their family histories, genetic profiles and experiences were split into two age groups – younger than 65 and 66 and situations,” he says. and older. Data was collected from Medicare and other Wetherall says she’s relieved to have been offered lumpec- insurance claim databases. tomy with radiation. In both age groups, the risk of complications in patients “The ‘less-is-more’ option was the right decision for me.” undergoing mastectomy and reconstruction was almost twice that of patients undergoing lumpectomy and radiation. The most common problems were infections, fluid buildup, breast pain, blood clots, implant removal or graft failure. Mastectomy and reconstruction was the most expensive therapy. The total cost within two years of diagnosis in the younger population was about $88,000, which was Caroline Wetherall says she was relieved when Benjamin Smith, M.D., told her her breast cancer treatment could be limited to lumpectomy and radiation. photo by Karen Warren / ©Houston Chronicle. Used with permission.

16 75 YEARS OF PROGRESS

Partnerships expand MD Anderson’s reach from coast to coast Anderson’s four newest partnerships are providing adult cancer patients in The Cancer Network MDCalifornia, Texas and New Jersey with access to the most advanced oncology by the numbers care in the country.

In November, MD Anderson and The University of Texas Health Growing in the Garden State Science Center at San Antonio announced an affiliation that will In April, MD Anderson and Summit Medical Group, the larg- Partner Members: provide care for patients in 38 South Texas counties. Through est and oldest physician-owned multispecialty practice in New 5 this agreement, the Cancer Therapy & Research Center of the Jersey, announced they would join together to form the Summit Banner MD Anderson Cancer Center UT Health Science Center will be known as UT Health San Medical Group MD Anderson Cancer Center, bringing world- (Gilbert, Arizona) Antonio MD Anderson Cancer Center when it opens this year. class cancer services to patients in northern New Jersey and the MD Anderson Cancer Center at Cooper At the new center, patients will have access to MD Anderson’s surrounding area. MD Anderson first brought its top-ranked (Camden, New Jersey) treatment protocols, standards of care, extensive clinical trials cancer care to the state in 2013, when it partnered with Cooper and translational research. University Health Care to create MD Anderson Cancer Center Baptist MD Anderson Cancer Center “Beyond all these obvious advantages is that we will be able to at Cooper in Camden, New Jersey. Summit Medical Group is an (Jacksonville, Florida) offer our region the very best care close to home,” says UT Health extension of MD Anderson at Cooper. MD Anderson’s partner- Summit Medical Group MD Anderson Science Center President William Henrich, M.D. ship with Summit is the first time the cancer center has partnered Cancer Center with a physician-owned-and-governed multispecialty group. (Berkeley Heights, New Jersey) Leveraging the UT System’s strengths Scripps MD Anderson Cancer Center In another move toward collaboration across the UT System, Better care for Southern California (San Diego) MD Anderson and The University of Texas Health Science In August, MD Anderson and San Diego-based Scripps Health On the way: Announced partnerships UT Center at Tyler announced a partnership in December that will agreed to an affiliation that creates Scripps MD Anderson Health San Antonio MD Anderson Cancer provide care for patients in northeast Texas and the surrounding Cancer Center. The center provides care to patients in eight Center and UT Health Northeast MD Anderson region. Through this agreement, UT Health Northeast’s Cancer Southern California counties, from Santa Barbara to the U.S.- Cancer Center take effect later in 2017. Treatment and Prevention Center will be known as UT Health Mexico border. Northeast MD Anderson Cancer Center when it officially “This new alliance gives Southern Californians easy access to Certified Members: 15 launches in late 2017. MD Anderson’s proven, research-based approach to cancer care,” The new cancer center will be fully integrated with MD Anderson says Scripps Health President and CEO Chris Van Gorder. “Our 15 health systems and hospitals in 12 states in Houston, which means Tyler patients will have access to partnership builds on Scripps’ history of providing exceptional the same high level of cancer care and clinical trials as those cancer care to our region and allows us to offer the best cancer in Houston. treatment available anywhere.” Associate Members: 3

UT Health Northeast MD Anderson will practice multidisci- Physicians and administrators from MD Anderson and Scripps Hospital Israelita Albert Einstein (São Paulo) plinary care based on MD Anderson’s model, and physicians in together oversee patient care and research at Scripps MD Tyler will collaborate with MD Anderson faculty members on Anderson, where patients have access to comprehensive can- MD Anderson Cancer Center Madrid clinical discussions and tumor boards to make recommendations cer care, including medical, radiation and surgical oncology; Vehbi Koc Foundation American Hospital for individual patients. pathology; laboratory and diagnostic imaging; and other clinical (Istanbul) and support services. “This partnership will help reduce cancer rates in our region, where citizens are among the unhealthiest in the state due to These most recent partnerships make Scripps MD Anderson, UT Affiliates: 2 lack of access to care,” says Kirk Calhoun, M.D., president of Health San Antonio MD Anderson and UT Health Northeast UT Health Northeast. MD Anderson part of MD Anderson Cancer Network, a global MD Anderson Radiation Treatment Center collaborative network of hospitals and health care systems ded- at American Hospital (Istanbul) The agreements between MD Anderson, UT Health San Antonio icated to MD Anderson’s mission to end cancer. and UT Health Northeast support the vision of UT System Presbyterian MD Anderson Chancellor William McRaven to create a “quantum leap” by Radiation Treatment Center building collaborative teams of UT System institutions based (Albuquerque, New Mexico) on the respective strengths and expertise of the institutions within the UT System.

17 MD Anderson Annual Report

Tonya Edwards helps patients deal with pain caused by their disease and treatment. photo by Wyatt McSpadden

18 75 YEARS OF PROGRESS

One nurse’s prescription for curbing pain pill addiction

By Ronda Wendler

sk Tonya Edwards how frequently she encounters cancer patients When drug misuse is detected, MD Anderson’s Opioid Safety Initiative squad pays the patient a visit. Team mem- Aaddicted to prescription painkillers, and she offers a weary reply. bers include Edwards, as well as a doctor, patient advocate, pharmacist and psychologist. Only a handful of hospitals “Every day,” she sighs. First responder across the country have such a resource. Edwards is a nurse in MD Anderson’s Supportive Care As a nurse, Edwards is on the front lines of the addiction Center, where health care providers help patients deal crisis. She’s first to see patients who show up unannounced, Compassionate care with pain caused not only by their disease, but also their demanding, cajoling or asking politely for more medication. “This isn’t about playing detective, spying on patients, or treatment. Some claim their pills have been lost or stolen, while others reprimanding them,” says Suresh Reddy, M.D., professor “Not everyone with cancer will have pain, but more than say they’ve run out of pills early, with no explanation. Then of Palliative Care and Rehabilitation Medicine. “The team’s half will,” Edwards says. “Our mission is to lessen their there are the “doctor shoppers” who seek opioids from sole purpose is to provide compassionate care to those who suffering.” multiple MD Anderson doctors in the hospital’s various need our help and to see them safely through their cancer departments. A few go so far as to visit emergency rooms j ou r n e y.” Prescription opioids, with brand names such as Vicodin, at other hospitals. “Our message to Oxycontin, Percocet and Fentanyl, have long proven supe- Together, patients, their families patients is, ‘We’ll rior to other drugs for easing cancer-related discomfort. “They use excuses — whiplash, back pain, toothache — and team members agree upon control your pain. It’s anything they can think of, to get the drugs,” Edwards says. a plan of action that includes up to you to control “These drugs interact with receptors in the brain to produce rules, boundaries and inter- A quick check of MD Anderson’s computerized patient your behavior.’” a powerful, pain-numbing effect,” says Eduardo Bruera, ventions. M.D., chair of Palliative Care and Rehabilitation Medicine. records and Texas’ statewide drug dispensing registry “They also make some patients feel happy, relaxed, even reveals who’s been making the rounds in search of pre- Almost always, the plan calls for euphoric.” scriptions. more frequent clinic visits — perhaps twice a week instead Over time, Edwards has learned to sense when she’s being of twice a month — to ensure opioids are being taken Such soothing and pleasurable effects can lead to addiction. as prescribed. Patients meet regularly with an addiction Most people won’t run into trouble when taking opioids “gamed,” but she doesn’t judge. Her first concern always is for each patient’s safety. counselor. Those on stronger pain pills are transitioned to prescribed for pain, but some will. weaker ones and offered other forms of pain management. “One in five people have a larger than average number of “This is a chronic disease that patients didn’t choose,” she Claims of lost or stolen medication must be backed up by opioid receptors in the brain,” Bruera explains. “These are says. “No one wakes up one morning and says, ‘I want to a police report before a new prescription can be written. the individuals who are predisposed to getting hooked.” get addicted to my opioid pills because it’ll be fun.’ This could happen to me, and it could happen to you.” And to prepare for a “worst-case” scenario, patients’ family members are provided with Narcan, a prescription nasal Opioid epidemic Extra attention spray that blocks the effects of opioids and reverses an overdose. The lure of addiction is the driving force behind an opioid Realizing the magnitude of the problem, Edwards devised epidemic that began slowly in the late 1990s and today a plan to help patients at risk, with assistance from Bruera All these measures can help, Edwards says, but patient has burgeoned into a public health crisis. Overdoses of and Supportive Care Center colleagues. cooperation is key. prescription painkillers and the illegal opioid heroin are killing more than 27,000 people a year. Put simply, it works like this: “Our message to patients is, ‘We’ll control your pain. It’s up to you to control your behavior.’” “No one is immune,” Bruera says. “Emergency rooms across Every patient who’s newly admitted to the Palliative Care the country are treating young and old, professional and Center completes two written tests that reveal whether The program launched a year ago and is working, says blue-collar, urban and rural, all races and backgrounds. they’re susceptible to addiction and how much supervi- Edwards, who for her efforts won this year’s Brown sion they may need. Foundation Award for Excellence in Oncology Nursing. The problem is seen everywhere, Bruera says, including The award is MD Anderson’s highest nursing honor. MD Anderson. Those whose test scores raise a red flag for potential abuse are closely monitored by clinic staff. If their behavior sug- “Most patients do much better when they understand that “Opioids are essential to controlling cancer pain,” he says, gests they’re already abusing drugs – for example, they ask certain behaviors are required,” she says. “A little extra “but those who fail to take the drugs strictly as prescribed for new prescriptions, claim their pills were lost, or request attention makes a big difference.” may find themselves dealing with cancer and addiction.” stronger opioids — they undergo a urine drug screen.

19 MD Anderson Annual Report

Leukemia was no match for her donor sister and a ‘reduced-intensity’ stem cell transplant By Ron Gilmore

Matthews’ sister Debbie was found to be a perfect match, and she happily donated stem cells to help her sibling battle cancer. The transplant kept Matthews in remission for 18 months, but her cancer came back. Her sister donated a second time in 2006, and Matthews’ remission has lasted ever since. “After each transplant, I was hospitalized for four weeks, then I had home care,” she says. “Since my second transplant, I see my doctor monthly and after each visit I receive five booster shots of azacitidine, an anticancer chemo- Cinda Matthews’ leukemia is in therapy drug. It’s obviously been remission after she underwent and will continue to be a long pro- a reduced-intensity stem cell cess, but the entire treatment has transplant that uses lower not been painful and I continue levels of chemo and radiation to live my life fully.” than those used in standard transplants. The procedure After her second transplant, allows older patients and those Matthews decided to join the who are sick or frail to receive ranks of the volunteers who lifesaving transplants. spent time with her during treatment. “I enjoyed visiting with the volunteers and appreciated their work during both of my long-term stays,” she says. “I’m so grateful for my treatment at Cinda Matthews underwent a “reduced-intensity” stem cell transplant to put her chronic myelomonocytic leukemia in MD Anderson and wanted to give to others something long-term remission. photo by Wyatt McSpadden of what had been given to me.” hen Cinda Matthews began working as a speech therapist in the As a volunteer, Matthews is especially touched by young W1960s at the Houston Speech and Hearing Center on the campus of mothers and fathers who undergo treatment and have to the Texas Medical Center, there were more trees than buildings. leave young children at home, often far away. “Some tell me they just want to survive to see their Little did Matthews know that years later, her life would Although Matthews wasn’t considered young enough children grow up,” she says. “Seeing my grandchildren depend on MD Anderson Cancer Center, only blocks for a full stem cell transplant, a less rigorous method of develop and grow was very important to me, so I can from where she’d worked. That life-altering revelation infusing stem cells from a matching donor had recently only imagine what a parent must feel.” came in 2003, when Matthews was diagnosed with been introduced. Known as a “reduced-intensity” trans- Today, Matthews, 74, enjoys time with her six grandchil- chronic myelomonocytic leukemia (CMML), a blood plant, the procedure uses lower levels of chemotherapy dren, husband, three daughters and friends. cancer that at the time had an average survival rate of and radiation to wipe out most, but not all, of the cancer two to five years. cells in the patient’s own bone marrow before replacing “I learned from this experience that many things happen them with a donor’s healthy cells. in life beyond our control,” she says, “and that caring, “I was totally surprised and upset with the initial diagno- smart doctors and nurses, as well as loving family and sis,” Matthews says. “I’d always been healthy. I was told “The advantage was that the reduced-intensity transplant friends, can make all the difference. The disease as well that chemotherapy might put my disease in remission, was much less risky,” says Matthews, “but my doctor as the treatment process has caused me to appreciate but it wouldn’t last. My only hope for long-term remis- also told me that only 1 in 3 patients who undergo the my many blessings. It’s deepened and strengthened my sion was a stem cell transplant.” procedure experience long-term remission.” faith and my relationships.”

20 75 YEARS OF PROGRESS

Routine pediatric exam uncovers extremely rare tumor By India Ogazi

Franco DeMonte, M.D., left, and Paul Gidley, M.D., are members of the Skull Base Tumor Program’s multidisciplinary team at MD Anderson. photos by Nick de la Torre

ike many parents, San Antonio residents Richard and Heather Delaney “They were thorough, knowledgeable and answered all almost skipped their daughter Kylie’s annual checkup. The 8-year-old of our questions,” Richard says. “As a physician, I really L appreciated that.” seemed healthy and wasn’t due for immunizations. But Heather decided Before surgery, Heather shaved Kylie’s favorite stuffed to keep the appointment anyway. animal — a kitten — to match Kylie’s pre-surgical hair- cut. Gidley and DeMonte successfully removed Kylie’s “Looking back, I’m so glad I did,” she says. The Delaneys, doctors themselves, selected Gidley to entire tumor, and the only remnant of her disease is perform their daughter’s surgery. During Kylie’s checkup, the pediatrician noticed an mild hearing loss. unusual mass in the girl’s middle ear and referred her “After speaking with the skull base tumor experts at “I’m so grateful we took Kylie for her checkup,” says her to a nearby hospital for further testing. MD Anderson, we knew this was the place for Kylie,” mom. “If we had waited one more year, the tumor could Heather says. “And, when we came to stay in the The result? Kylie was diagnosed with a rare, noncancer- have grown into her brain.” MD Anderson Rotary House Hotel, everyone was so ous bone tumor called an osteoblastoma. These tumors nice — it just felt right.” Gidley also points to the important role Kylie’s annual usually develop in the bones of the spine, legs, hands exam played in the discovery of her tumor. and feet. But Kylie’s tumor was located in her temporal “Plus, it was so close to San Antonio, which made it very bone, which encloses the ear. convenient for us,” adds Richard. “The fact that her pediatrician completed a thorough checkup and recognized the abnormality makes her the “Only 35 cases of this tumor type have ever been docu- Before surgery, the couple met with Gidley and neuro- hero in this story,” Gidley says. mented, and Kylie is one of the youngest patients ever,” surgeon Franco DeMonte, M.D., co-director of the Skull says Paul Gidley, M.D., a neurotologist and skull base Base Tumor Program. The doctors would work together tumor surgeon at MD Anderson. to remove the portion of the tumor near Kylie’s brain.

21 MD Anderson Annual Report

Cancer Prevention: How a division came together

By Clayton Boldt, Ph.D.

he commitment to ending cancer through prevention isn’t new for current vice president and division head, Ernest Hawk, M.D., who he describes as “the clear choice.” T MD Anderson, but it has evolved over time. Hawk focused first on clarifying the division’s four mission-oriented domains — research; clinical care; The institution’s Division of Cancer Prevention and recruiting a multidisciplinary group with an initial focus education, training and mentoring; and cancer control Population Sciences began as a fledgling program with on tobacco, says Levin. — all with a focus on translating research into services just 35 faculty and staff members in 1979. Today it’s one However, LeMaistre’s efforts were not met without con- that benefit individuals, future generations, and the com- of the largest and most respected prevention programs troversy. Levin, who’s now retired and living in New York, munity at large. This required in the nation. recalls opposition from senior scientists and clinicians better communication across Over the past four decades, the division’s success and who either did not understand the vision or thought departments and establishing In 1979, Charles LeMaistre, growth required strong institutional dedication and just resources were better used elsewhere. a clear vision for progress in M.D., then president of the right catalyst to get things started. MD Anderson, created Nevertheless, with LeMaistre’s support, Levin was able to each of these domains, he says. That initial push came from Charles LeMaistre, M.D., turn the dream into reality. He recruited leading faculty in “The vision was much aligned the Division of Cancer the second president of MD Anderson. the field of prevention, which helped MD Anderson build with the institution’s vision to Prevention. He envisioned a strong reputation in the cancer prevention community. be a change agent in cancer recruiting a multidisciplinary “Dr. LeMaistre possessed a longtime interest in cancer group of doctors and prevention,” says Bernard Levin, M.D., the first vice “These were really first-rate people,” Levin says. “The prevention,” says Hawk. “It was all about making science scientists, with an initial president and head of the division. “He really believed prominence of these individuals at a national level helped focus on tobacco. this was an important new direction for the institution. establish this as an effort of high quality. It was pulling relevant to the clinic and the It would never have happened without him.” its own weight in every sense.” patients we serve as well as to the broader public.” LeMaistre bolstered the existing cancer prevention For 13 years, Levin oversaw expansion of research and program by raising it to new prominence and formally clinical services, new departments and even a new divi- Hawk’s vision was aided by “transformative” philanthropic creating the Division of Cancer Prevention. He envisioned sion name. When he retired, he transferred the reigns to gifts, which established the Duncan Family Institute for Cancer Prevention and Risk Assessment and the Lyda Hill Cancer Prevention Clinic. When it was created in 1979, the Division of Cancer Prevention, which is now known as the Division of Cancer Prevention and Population Sciences, was focused on three main areas: Now with more than 500 faculty and staff, the division Preventive Epidemiology, to identify markers of risk; Health Maintenance, to detect and remove continues to provide high-quality care to patients and to cancers early; and Health Education, to disseminate information on the causes of cancer and help implement and disseminate evidence-based actions lifestyle changes to health professionals and the public. Much has changed in the past 40 years. in public policy, public and professional education, and Here’s a look at some of the highlights: community-based services.

1978 1979 1986 1988 1989 1991 1992

The Texas The Division of Cancer The Department of Cancer All prevention The division expands to Bernard Levin, The Department of Legislature Prevention is created on Prevention and Control activities are placed two departments, Cancer M.D., is named Behavioral Science appropriates Sept. 1, 1979, with a staff of — the division’s only under the direction Prevention and Control and ad interim vice is created. $160,810 for 35 (including faculty). It was department — oversees of the VP for Patient Studies. Its programs president of Cancer “prevention” at formalized as an integral four main programs: Clinical Academic Affairs. include Clinical Epidemiology, Prevention. MD Anderson. part of the institution’s Epidemiology, Nutrition, Nutrition Research and mission in 1980. Community Oncology and Application, Behavioral Behavioral Research. Research, Prevention Clinic, Professional Education, Outreach Activities and the Cancer Prevention and Detection Program.

22 75 YEARS OF PROGRESS

Responding to a growing need to better understand and demonstrate the value of all aspects of cancer care, Hawk led the creation of the Department of Health Services Research. The department’s goal is to study health care delivery and its outcomes, so that safety, timeliness, effectiveness, efficiency and equity of care will be better measured and promoted. Researchers use a patient-centered approach that addresses each person’s cultural, socioeconomic and medical needs. Research focuses on healthy individuals, those currently battling cancer, and those who have completed cancer treatment. The cancer prevention and control platform, part of MD Anderson’s Moon Shots Program™, is committed to extending prevention efforts beyond MD Anderson’s walls, particularly for the uninsured and underserved. “Serving those in greatest need is something I think everyone in our division is very passionate about, but it’s hard to reach all the places where it’s needed,” says Hawk. “So I think we’ve been creative in trying to study and serve those communities in a variety of ways.” With a foundation in stellar research, Hawk looks forward to continued success for the division. As new discoveries clarify the connections between lifestyle factors and cancer risk, MD Anderson will continue to translate those discoveries into actionable interventions. “It’s the greatest place in the world for these types of initiatives,” Hawk says. Ernest Hawk, M.D., head of Cancer Prevention and Population Sciences photo by Wyatt McSpadden

1994 2004 2007 2008 2010 2012 2013

The Division of Cancer To better reflect its Levin retires as vice The Duncan Family The Department The Moon Shots The Lyda Hill Cancer Prevention is formed on expanded scope, the president and division Institute for Cancer of Health Services Program and the Prevention Center Aug. 1, 1994, and Levin division is renamed head in August. In Prevention and Research is Cancer Prevention is established. is named vice president the Division of November, Ernest Hawk Risk Assessment created. and Control Platform and division head. In Cancer Prevention is named vice president is created. are created. December 1994, the and Population and division head. division expands to Sciences. three departments: Behavioral Science, Health Disparities Epidemiology, Clinical Research becomes Cancer Prevention and the division’s fourth one core, the Basic department. Science Laboratory.

23 MD Anderson Annual Report

moon shots program clinical and translational research

photo by Adolfo Chavez III 24 75 YEARS OF DISCOVERY

“We have every opportunity in the world to find here in Houston the answer to the question of the cause and cure of cancer.”

— Dudley Woodward, chairman of The University of Texas System Board of Regents from 1944-55 75 years of discovery

Since day one, MD Anderson researchers have worked tirelessly to find an answer to cancer. In that time, they’ve made great progress in understanding the disease — how it adapts, survives and spreads. Three-quarters of a century later, the institution’s labs and research institutes continue to turn out discoveries and breakthroughs that lead to better and more effective treatments for cancer patients. In many of today’s labs, experts from different fields who have a shared research vision are brought together in the same space to encourage collaboration, communication and creativity, which are vital to the rapid and dramatic reductions in death and suffering that are at the heart of the Moon Shots Program™. MD Anderson doctors and researchers are building on the success of immune checkpoint blockade drugs, which are now approved for many late-stage cancers. They also are learning why these drugs don’t work for all patients. And through the Moon Shots™ platforms, new and innovative drugs and therapies are being developed to fight the disease. And the research continues to pay off. Just as the amount of money invested in cancer research at MD Anderson has grown each year — from just over $15,000 in 1944, to more than $787.3 million in 2016 — the five-year survival rates for cancer patients have continued to rise.

clinical trials genomics biostatistics drug development molecular pathology proteomics cancer biologybiomarkers epigenetics longitudinal data

25 MD Anderson Annual Report

Impressive results against BRCA-positive breast cancer show drug’s game-changing potential By Scott Merville

fter every breast cancer patient responded positively to a new targeted A therapy in a first-of-its-kind clinical trial, MD Anderson researchers have quickly taken the next step toward potentially establishing a new standard of care.

After just two months of treatment with a drug called a PARP “After we saw the extensive clinical response, confirmed by inhibitor, tumors in all 13 newly diagnosed breast cancer ultrasound, and with a favorable toxicity profile, we really patients shrank significantly. wanted to move forward into an extension to evaluate this drug as a single treatment,” Litton says. “If the extension study Tumors shrank anywhere from 30% to 98% with a median produces similarly strong results, the next step would be to reduction of 88% in the 13 patients studied. directly compare talazoparib to chemotherapy in the presur- PARPs — short for Poly (ADP-ribose) polymerase — are gical, curative setting.” proteins that can help different types of cells, including cancer Chemotherapy may even be delayed or replaced if the exten- cells, repair and survive damaged DNA. Inhibiting PARPs can sion trial is similarly effective and shows less toxicity than the keep cancer cells from surviving DNA damage and spreading. initial trial, she adds. “Acknowledging that this is a small study, I can’t think of any PARP inhibitors are approved by the Food and Drug drug-based therapy that gives results this consistently strong Administration for advanced ovarian cancer, but are not yet in only two months,” says Jennifer Litton, M.D., associate approved for breast cancer. professor of Breast Medical Oncology and leader of the study. Jennifer Litton, M.D., associate professor of Breast Medical Oncology photo by Nick de la Torre Litton originally expected the study would sign up 20 patients in two years. Instead, 13 enrolled in eight months, and the results were striking enough that the study was stopped in The Moon Shots Program is paving the way to faster results early 2016. In addition to the trials above, Litton is principal inves- tion, providing a unique opportunity for researchers An extension of the study to enroll 20 more patients began in tigator of an international clinical trial of talazoparib and the drug company to better understand how the August, and is filling quickly. for patients with advanced or metastatic breast cancer drug works and identify patients who will respond in The idea is to first give the PARP inhibitor talazoparib to who have been previously treated. advance. newly diagnosed patients who also have BRCA mutations. To more quickly offer talazoparib to newly diagnosed Biopsies taken before and after PARP inhibition are BRCA-related cancers, including ovarian cancer, are thought patients who have not undergone surgery, Litton pro- evaluated for DNA and RNA changes, and proteom- to be vulnerable to PARP inhibitors. Currently, a chemother- posed an investigator-initiated pilot study backed by ics (proteins) by Gordon Mills, M.D., Ph.D., chair and apy combination followed by surgery is the frontline therapy. MD Anderson’s Moon Shots Program™. The pharma- professor of Systems Biology. In the initial trial, patients agreed to delay chemotherapy and ceutical company that owns the drug agreed to the Helen Piwnica-Worms, Ph.D., vice provost for science first take talazoparib for two months, then proceed to chemo- study. Litton noted that institutional support through therapy and surgery. In the extension trial, patients are treated the Moon Shots Program helped convince the com- and professor of Experimental Radiation Oncology, only with talazoparib before surgery. pany to provide the drug for her trials. Moon Shot™ and colleagues harvest tissue samples from patients’ backing decreased the time needed to launch the first tumors that can be transplanted into mice to further None of the 13 patients had to withdraw from the first trial study how tumors respond to treatment. due to side effects, which were limited mainly to fatigue and trial by about two years, she estimates. “We will be able to learn a great deal,” Litton says. low blood counts. Eight of the 13 had triple-negative dis- Extensive, unique biomarker research ease — a difficult-to-treat breast cancer that doesn’t have the “These models that are being built will be available cancer-promoting HER2 protein or two hormones (estrogen The pilot and extension studies also tap Moon Shots for multiple investigators in the future to study and and progesterone) that fuel breast cancer growth and can be Program resources for extensive biomarker evalua- test other drugs and drug combinations.” targeted by anticancer drugs.

26 75 YEARS OF DISCOVERY

BRCA1 and BRCA2 are tumor- suppressing genes and are found to have mutations in 5 to 10% of all breast cancer patients. BRCA-related cancers, including ovarian cancer, are thought to be vulnerable to PARP inhibitors.

27 MD Anderson Annual Report

Cutting off a cancer’s food supply or decades, combination chemotherapy has been the main treatment for patients with acute myeloid A drug developed at MD Anderson to starve cancer F is tested on an aggressive leukemia leukemia (AML) – an aggressive cancer of the blood and bone marrow. By Scott Merville “About 40 percent of younger patients survive long term, and for those over 65, survival drops to 10 percent,” says Marina Konopleva, M.D., Ph.D., professor of Leukemia. “There’s been no drug approved for the last 40 years for AML, and outcomes haven’t significantly improved with targeted therapies.” Researchers at MD Anderson’s Institute for Applied Cancer Science (IACS) are hoping to put an end to that drought with a drug they developed to starve these malignant blood cells to death. The initial Phase I clinical trial of the drug known as IACS-10759 opened for patients in October, a milestone for IACS, which acts as a biotech company embedded in a cancer center. The institute connects MD Anderson faculty with drug discovery and development expertise. “We’re hopeful we’ll soon see in patients the promising response to IACS-10759 that we observed in preclinical models,” says Giulio Draetta, M.D., Ph.D., head of Therapeutics Development and director of IACS. While researchers have found AML to be vulnerable, they’ve also discovered that sub- groups of tumors in lymphoma, glioblastoma, melanoma, colorectal and pancreatic cancers harbor this weakness. Leukemia and Lymphoma Society funds innovative trial Konopleva and Naval Daver, M.D., assistant professor of Leukemia, lead the AML trial, which is funded by a $3.5 million investment from the Leukemia and Lymphoma Society under its Therapy Acceleration Program, part of an intensive campaign the society launched against AML in late 2016. IACS aims to provide MD Anderson physicians and patients access to novel drugs tailored specifically to vulnerabilities found in tumors of unique groups of patients. These projects are based on findings coming from basic scientists at MD Anderson. “The IACS model emphasizes the need for us to deeply understand the biological effects of drugs,” Draetta says. “We want to increase the precision with which we identify and develop new molecules, and to ask critical questions about the effects of any new drug within the most relevant contexts.” Putting cancer on a lethal diet Based on an approach discovered by the institute, IACS-10759 is designed to target a metabolic vulnerability of AML cells. Most cells rely on two metabolic processes to survive. Cellular organelles called mitochondria use oxygen to convert energy stored in sugars, fatty acids and proteins into energy through a process called oxidative phosphorylation (OXPHOS). Cells also convert glucose to energy in the absence of oxygen through a less efficient process called glycolysis. IACS-10759 inhibits OXPHOS, thus one of two arms of metabolism that provide energy and building blocks to cancer cells. Joseph Marszalek, Ph.D., head of Translational Biology for the Center for Co-Clinical Trials, and Emilia Di Francesco, Ph.D., associate director of Medicinal Chemistry at the Institute for Applied Cancer Science photo by Wyatt McSpadden

28 75 YEARS OF DISCOVERY

AML FACTS Konopleva says her team’s research has shown that AML cells are highly depen- Acute myeloid leukemia occurs when dent on these mitochondria-driven the myeloid stem cells that usually processes. become healthy versions of some types of white blood cells, platelets or red “OXPHOS is how they survive, but no blood cells instead become immature one has had a clinically viable inhibitor,” versions of those cells. she says. The Leukemia and Lymphoma Society Enter IACS, where scientists, applying estimates there were 19,950 new cases their drug development expertise and of AML diagnosed in 2016, mostly in capacity for rapidly testing and under- adults, and the disease caused some standing the mechanism of possible 10,430 deaths. drugs in preclinical models, developed IACS-10759. “Normal cells can get around OXPHOS inhibition by turning up glycolysis, but we’ve identified some cancers like AML that can’t do that enough to survive,” says Joseph Marszalek, Ph.D., head of Translational Biology for the Center for Co-Clinical Trials. “We’re already working closely with several MD Anderson Cancer Moon Shots Program™ teams to develop IACS-10759 treatment for patients whose tumors rely on oxidative phosphorylation,” says IACS Executive Director Philip Jones, Ph.D. Create, test, refine, test again It’s taken a team of more than 25 people to successfully bring IACS-10759 into clinical trials. Emilia Di Francesco, Ph.D., associate director of Medicinal Chemistry at IACS, leads a group that crafts small-molecule drugs to efficiently hit targets in cancer cells Marina Konopleva, M.D., Ph.D., professor of Leukemia photo by Wyatt McSpadden while avoiding off-target effects. Marszalek’s group puts those drugs to the test in cell lines and mouse models. What A clinical trial takes on a deadly blood cancer they discover about the drug’s efficacy and side effects is fed back to Di Francesco’s group, which fine-tunes the drug. with an experimental drug

This intensive, reiterative process allowed them to analyze a series of molecules over IACS-10759 was developed by the Institute for Applied Cancer Science, which was 18 months before zeroing in on IACS-10759 for development. established in 2011 to develop new treatment options for cancer patients. IACS is a “We needed to refine the drug for the clinic and build in all the properties to make it platform of the Moon Shots Program™ — the ambitious effort launched in 2012 to more effective in patients,” Di Francesco says. reduce cancer deaths by more rapidly developing and implementing advances in prevention, early detection and treatment based on scientific discoveries. Marszalek and Di Francesco say the collaborative nature of MD Anderson clinicians is invaluable. They connected with Konopleva, whose knowledge of AML and preclin- The trial will enroll up to 48 patients with relapsed or resistant AML. ical models was vital to developing IACS-10759 and has enabled the development of Primary goals: Determine the safety and tolerability of the drug, establish a clinical assays to study the biology of OXPHOS inhibition in the ongoing clinical trial. maximum tolerated dose and a recommended dose for a Phase II trial. Additionally, the institute has a pipeline of other experimental drugs working their way Secondary goals: Learn more about the drug’s pharmacokinetics and early toward first-in-human use, with others expected to enter clinical trials in the next year. indications of clinical impact, including overall response rates, duration of “There’s no shortage of good ideas at a place like MD Anderson,” Jones says. “Identifying response, progression-free survival and overall survival. therapies that will be impactful for specific patient populations and moving those The expansion phase allows for enrollment of 12 patients to receive the medicines into clinical trials at MD Anderson is our mission.” recommended Phase II dose. Leukemia and Lymphoma Society funding also provides for analysis and development of biomarkers for the drug.

29 MD Anderson Annual Report

Breakthrough research leads to new hope for patients resistant to immunotherapy

By Leslie Loddeke

tories of immunotherapy’s success against metastatic melanoma in patients such as former SPresident Jimmy Carter are well publicized, but the treatment doesn’t work for everyone. In fact, checkpoint blockade drugs such as pembrolizumab and nivolumab, “These results allowed us to devise a means of combating resistance to which inhibit protein molecules on T cells that keep the immune system immunotherapy due to PTEN loss in melanoma patients,” Peng says. from attacking tumors, only work for about one-third of patients. Findings of the study, which was Cancer Discovery’s February 2016 cover Why do some tumors respond to immunotherapy and others don’t? story, have led to a Phase I and II clinical trial that will test a combina- That’s a question MD Anderson’s Weiyi Peng, M.D., Ph.D., and her team tion of immunotherapy and targeted therapy in patients with metastatic of investigators are getting closer to answering. melanoma who lack the PTEN gene. Peng, an assistant professor of Melanoma Medical Oncology, led a study Hussein Tawbi, M.D., Ph.D., associate professor of Melanoma Medical that showed a link between the loss of a tumor-suppressor gene called Oncology, is leading the Phase I and II clinical trial of pembrolizumab, PTEN and resistance to checkpoint inhibitor immunotherapy. an FDA-approved anti-PD-1 antibody, and GSK2636771, a PI3K-beta inhibitor, in patients with metastatic melanoma who lack the PTEN gene. Patients with inactive PTEN had fewer T cells in their tumors, indicating that a lack of PTEN suppresses the immune response against melanoma. The study represents the first clinical trial to test the effects of the PI3K-beta Patients with inactive PTEN also had worse outcomes when treated with inhibitor in melanoma patients checkpoint inhibitors compared to melanoma patients with intact PTEN. — and the first to test its effects in combination with immuno- These findings indicate PTEN loss may be an important biomarker to How checkpoint therapy in any cancer type. predict melanoma patients’ resistance to immunotherapy. The study also blockade drugs work showed that treatment with an experimental drug that blocks a molecular “About one-third of melanoma pathway called PI3K improved the effectiveness of anti-PD-1 treatment patients respond to pembroli- PD-1 is a checkpoint protein on T cells — white blood in laboratory models of melanomas with loss of the PTEN gene. zumab, which means there are cells that find and kill invaders — that acts as an “off two-thirds of patients in whom switch” when it binds with the protein PD-L1 on healthy we need to do better,” Tawbi cells, protecting them from attack. However, PD-L1 can says. “This trial is a very sig- also be found on cancer cells, allowing them to prevent nificant step in that direction.” an immune response by joining with a T cell’s PD-1. Anti-PD-1 immunotherapies target the checkpoint and This research and trial capitalize prevent it from binding with PD-L1 on a cancer cell, on the skills of targeted therapy effectively turning “on” an immune attack against cancer. experts such as Michael Davies, M.D., Ph.D., deputy chair of Melanoma Medical Oncology and co-leader of the Melanoma Moon Shot™, and immune therapy experts like Peng and Patrick Hwu, M.D., chair of Melanoma Medical Oncology and head of Cancer Medicine. Davies and Hwu were co-senior authors on the article. “This exciting clinical trial builds upon the collaborative research we have undertaken at MD Anderson to understand the interactions between oncogenic signaling pathways in cancer cells and the regulation of the anti-tumor immune response, based on our extensive expertise and resources in these two areas,” Davies says. “In addition to representing an important new clinical trial for patients with advanced melanoma, the results and translational research from this trial may have impact for the many other cancer types in which loss of PTEN occurs.” Hussein Tawbi, M.D., Ph.D., associate professor of Melanoma Medical Oncology photo by Wyatt McSpadden

30 75 YEARS OF DISCOVERY

Weiyi Peng, M.D., Ph.D., assistant professor of Melanoma Medical Oncology photo by Wyatt McSpadden

31 MD Anderson Annual Report

Meet the visionary leader of Pediatrics who’s on a ‘research and destroy’ mission

By Katrina Burton

fter his own diagnosis at age 13, Richard A Gorlick, M.D., set out on a lifelong journey to end cancer in children.

Along the way, he has focused his clinical and research studies on sarcomas — tumors that grow in connective tissues including the bones, muscles, tendons and cartilage. These are the same tumors that interrupted his teenage years. Now, the physician-scientist’s journey has brought him to MD Anderson Cancer Center, where, as division head and chair of Pediatrics, he’ll use his pediatric oncology expertise and experience as an educator, clinician, scientist and cancer survivor to help children, adolescents and young adults treated at MD Anderson Children’s Cancer Hospital. “Research, clinical care and education are all important priorities,” says Gorlick. “Providing multi-disciplinary care, minimizing the burden to patients and families, and developing a global model for treating young cancer patients are all important to me.” Gorlick’s MD Anderson laboratory focuses on targeted therapies, new drugs for childhood cancers, and understanding the mechanisms behind the development and progression of osteosarcoma, the most common form of childhood bone cancer. Gorlick, whose research resulted in the establishment of the world’s largest osteosarcoma tissue bank, leads the Bone Tumor Disease Committee for the Children’s Oncology Group, a collaborative clinical trials system and the largest organization focused exclusively on pediatric cancer research. He is drawing on that spirit of teamwork to forge collaborations with MD Anderson colleagues who’ve seen success using adult therapies such as immunotherapy and genetic profiling, which can ensure the right drugs get to the right patients. “Therapies developed for adults don’t become effective therapies for children as quickly as they should,” says Gorlick. “Children aren’t simply small adults, they are unique, and we must acknowledge and study their unique- ness. That includes pursuing funding to support childhood cancer research, which is often lacking.” Richard Gorlick, M.D., will lead research focused on targeted therapies and new drugs for childhood cancers, as well as a more complete understanding of osteosarcoma. photo by Wyatt McSpadden

32 75 YEARS OF DISCOVERY

Better data — and more of it — translates to better care “Cancers are exceptionally adaptive in the face of treatment pressure,” says Andrew Futreal, Ph.D., chair of Genomic Medicine and co-leader of MD Anderson’s Moon Shots Program™. “We know a tumor after therapy is likely to be different than before, but we haven’t done a good job of tackling this from a research perspective until now.” To understand how tumors evolve and resist treatment, Futreal is helping lead APOLLO, which stands for Adaptive Patient-Oriented Longitudinal Learning and Optimization. It’s a systematic approach that relies on taking blood samples and biopsies before, during and after treatment, and conducting deep molecular and immune analysis of those tumor samples to understand what causes them to respond to or resist a given treatment. In the next two years, APOLLO is scheduled to conduct such analyses in 2,100 patients enrolled in 28 high-priority clinical trials for melanoma, multiple myeloma, glioblastoma, lymphoma, sarcoma, lung, breast, colorectal, pancreas and ovarian cancers, and cancers caused by the human papillomavirus. Results of these analyses, plus clinical information, will be added to the Translational Research Accelerator (TRA), which is a big data platform that integrates longitudinal clinical and research data — the same sample tracked at different points in time — to support translational research throughout the institution. These enormous amounts of data are housed in data centers like the one pictured here. Information from approximately 250,000 patients treated at MD Anderson since 2012, along with research data from Moon Shots™ platforms, has been loaded into the secure database. The TRA will provide researchers with an unprecedented capacity to more quickly and efficiently generate science-based inquiries in the pursuit of better cancer treatment. “APOLLO, with its pipeline of comprehensive data feeding the Translational Research Accelerator, drives our vision of every patient contributing to, and potentially benefiting from, research,” says Futreal.

— Scott Merville Enormous amounts of data that can benefit researchers in their pursuit of cancer breakthroughs are housed in MD Anderson data centers such as this one. photo by Nick de la Torre

33 MD Anderson Annual Report

ORBIT revolves around collaborative partnerships

by Ron Gilmore

Anderson’s ORBIT program may have an otherworldly name, MDbut the Oncology Research for Biologics and Immunotherapy Translation unit was established and continues to thrive through purely Earth-bound partnerships that pair novel therapeutic targets discovered at MD Anderson with state-of-the-art pharmaceutical technologies for biologic drug development.

Since its inception in 2014, ORBIT’s primary mis- “Hematologic cancer is certainly a current area of sion has been to develop innovative monoclonal interest for ORBIT in terms of novel mAb discov- antibodies — “magic bullets” that first recognize ery,” says Toniatti. “However, we are agnostic about specific target molecules on the surface of cancer tumor type as far as we have good targets. The rea- cells, then zero in to kill the cells. son why we can be agnostic is that MD Anderson has experts in almost every type of cancer.” ORBIT is one of the three drug development platforms that support MD Anderson’s Moon One potential new therapy for leukemia is h8F4, Shots Program™ and grew out of a $330 million a mAbs invented by Molldrem, which targets alliance with GlaxoSmithKline to develop in a specific peptide expressed on the surface of the clinic an OX40 agonist antibody generated acute lymphocytic leukemia. ORBIT acceler- at MD Anderson. The OX40 mAb, now named ated its development by funding the start of the GSK3174998, entered the clinic in late 2015 manufacturing process for the antibody, creating and is now in the advanced stage of a Phase I a detailed, three-year plan to bring the drug to trial. ORBIT works closely with MD Anderson’s clinic, and contacting potential pharmaceutical Strategic Industry Ventures (SIV) office to company partners. develop partnerships — primarily with biotech As a result, in April 2015, MD Anderson signed an and pharmaceutical companies — in an effort agreement with the international drug company to quickly develop new antibody-based cancer Astellas Pharma Inc., to develop h8F4, which will therapies that can be brought to clinical trials at enter the clinic in mid 2017. an accelerated pace. “Current treatments for aggressive leukemias are Today, ORBIT is comprised of a core group often toxic,” says Molldrem. “We are developing of 16 people led by Executive Director Carlo a safer, more potent therapy for cancers with Toniatti, M.D., Ph.D., and Scientific Directors poor survival outcomes. Jeffrey Molldrem, M.D., professor of Stem Cell photo by Adolfo Chavez III We hope this important Transplantation and Cellular Therapy, and Collaboration with biotech collaboration will allow us Michael Curran, Ph.D., assistant professor of and pharmaceutical companies is to deliver much-needed Immunology. The team works closely with col- crucial given the high cost of drug antibody-based treatment leagues in a number of MD Anderson’s clinical development. In addition to h8F4, to patients’ bedsides more departments to fight melanoma, prostate, ovarian ORBIT has four immune checkpoint quickly.” and hematologic cancers, among others. programs and one T cell receptor antibody in various stages of Although ORBIT is focused on advancing novel development. therapeutics for several forms of cancer, the development of a novel antibody-based therapy for hematologic cancers has shown great promise and will enter Phase I trials early this year.

34 75 YEARS OF DISCOVERY

Graduate School emphasizes ‘core’ value EDUCATION AND TRAINING

With a commitment to educating and training the next generation of for research students cancer doctors, researchers, nurses and health care professionals, MD Anderson offers a number of degrees in biomedical sciences and By Gillian Kruse allied health professions, as well as nursing training programs and more. Graduate School of Biomedical Sciences he transition from undergraduate studies to graduate research can be daunting. T Degrees awarded But for first-year students at The University of Texas The course evolved as students and instructors adjusted to Master of Science 11 MD Anderson Cancer Center UT Health Graduate School the new format. Students gave feedback in weekly surveys Specialized Master of Science 9 of Biomedical Sciences (GSBS), the school’s Core Course is on what worked and what didn’t, and their suggestions were cushioning that bumpy ride. included in the following week’s sessions. Combined M.D./Ph.D. 4 Ph.D. 59 “The Core Course helped me adjust to the life of a researcher The nontraditional structure also meant students were able in a big way,” says Kimiya Memarzadeh, a third-year graduate to pick up some of the soft skills necessary for becoming student in Neuroscience. “It really helped me become more successful scientists. Most degrees awarded analytical and not take things at face value.” “I had to give a presentation to about 30 people in another Cancer Biology 14 The GSBS premiered the course for incoming first-year course, which I normally would have found nerve-racking,” Biomedical Sciences 13 students in the fall of 2014 to give them a foundation of Memarzadeh says. “But because we’d received practice and Experimental Therapeutics 10 science and research skills they’d need to succeed in their tips on presentation skills each week in the core course, individual programs. I was confident I’d deliver a solid presentation.” Medical Physics 9 Genetic Counseling 8 Previously, each of the 13 GSBS programs had its own Students also formed friendships that may someday further curriculum and graduation requirements, with no course their careers. standardization and very little communication between School of Health Professions “People often say that it’s not what you know, but who programs. Dean Michelle Barton, Ph.D., knew a core course you know,” Memarzadeh notes. “I’ve formed relationships Bachelor of Science degrees awarded 143 for every first-year student would help new students become with fellow students and faculty members I wouldn’t have acclimated to the many aspects of the academic biomedical Diagnostic Imaging ...... 34 encountered otherwise. These people are my future mentors, research world. Molecular Genetic Technology ...... 13 collaborators and potential employers.” “We develop the leaders of the future here,” she says. “In any Radiation Therapy ...... 21 This story originally appeared in Messenger, MD Anderson’s field they enter — research, science policy, law, pharmaceu- ...... magazine for employees, volunteers, retirees and their families.. Medical Dosimetry 16 ticals or biotechnology — it will be ingrained in them to use Clinical Laboratory Sciences ...... 14 their leadership skills and work collaboratively.” Cytogenetic Technology ...... 18 Starting from scratch Histotechnology ...... 15 Based on input from all 13 GSBS programs, the course, titled Diagnostic Medical Sonography ...... 6 Foundations of Biomedical Research, launched in January Cytotechnology ...... 6 2014 with 41 students enrolled. A different faculty member led each of the 15 weeks, with guest lecturers from various departments giving overviews of their areas. Wednesday Master of Science degrees awarded mornings were reserved for biostatistics, since that had been Diagnostic Genetics ...... 6 identified as a weak area for young researchers. There were no exams; instead students were evaluated on Educational trainees take-home exercises and group projects. By the time the ...... course ended, students had interacted with more than Clinical 1,693 70 faculty members from different specialties. Research ...... 1,847 “Because this was so different from anything we’d done Special programs ...... 56 before, we had to really come at this with an open mind,” Student programs ...... 810 Barton says. School of Health Professions programs ...... 317 Nursing programs ...... 1,499 Observers ...... 782 Total ...... 7,004 35 MD Anderson Annual Report

THE UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER SHARED GOVERNANCE COMMITTEE

Marshall E. Hicks, M.D. Stephen Hahn, M.D. Robert Brigham Thomas Buchholz, M.D. Ethan Dmitrovsky, M.D. President ad interim Deputy President and Senior Vice President, Executive Vice President Executive Vice President Chief Operating Officer Hospitals and Clinics and Physician-in-Chief and Provost

Giulio Draetta, Ph.D., M.D. Dan Fontaine, J.D. Richard Gorlick, M.D. Carin Hagberg, M.D. Stanley Hamilton, M.D. Co-leader, Moon Shots Program Executive Vice President, Division Head, Division Head, Division Head, Pathology and Institute for Applied Cancer Administration Pediatrics Anesthesiology and and Laboratory Medicine Science Platform Critical Care

Ernest Hawk, M.D., M.P.H. Steven Haydon Mien-Chie Hung, Ph.D. Patrick Hwu, M.D. Julie Izzo, M.D. Vice President and Division Vice President and Chair, Molecular and Division Head, Chair, Faculty Senate Head, Cancer Prevention Chief Legal Officer Cellular Oncology Cancer Medicine and Population Sciences

Osama R. Mawlawi, Ph.D. Helen Piwnica-Worms, Ph.D. Tadd Pullin Stephen Swisher, M.D. David Tweardy, M.D. Chair-elect, Faculty Senate Vice Provost, Science Senior Vice President, Division Head, Surgery Division Head, Institutional Advancement Internal Medicine

Randal S. Weber, M.D. Gary Whitman, M.D. George Wilding, M.D. Crista Latham Shibu Varghese Chair, Head and Past Chair, Vice Provost, Clinical and Vice President, Vice President, Neck Surgery Faculty Senate Interdisciplinary Research Strategic Communications Human Resources (non-voting) (non-voting)

36 ADMINISTRATION

OFFICE OF THE PRESIDENT OFFICE OF THE PROVOST AND OFFICE OF THE EXECUTIVE VICE PRESIDENT EXECUTIVE VICE PRESIDENT AND PHYSICIAN-IN-CHIEF Marshall E. Hicks, M.D. President ad interim Ethan Dmitrovsky, M.D. Thomas Buchholz, M.D. Provost and Executive Vice President Executive Vice President and Physician-in-Chief Stephen Hahn, M.D. Deputy President and Chief Operating Officer Robert C. Bast Jr., M.D. Robert Brigham Vice President, Translational Research Senior Vice President, Hospital and Clinics Tadd Pullin Senior Vice President, Institutional Advancement Diane Bodurka, M.D. John Bingham Vice President, Medical Education Vice President, Performance Improvement and Crista Latham Chief Quality Officer Vice President, Strategic Communications Oliver Bogler, Ph.D. Senior Vice President, Academic Affairs Lewis Foxhall, M.D. Mark Moreno Vice President, Global Academic Programs Vice President, Health Policy Vice President, Governmental Relations Aman Buzdar, M.D. Joel Lajeunesse Patrick Mulvey Vice President, Clinical Research Administration Vice President, Pharmacy Vice President, Development Maureen Cagley Paul Mansfield, M.D. Vice President, Academic Operations Vice President, Acute Care Services OFFICE OF ADMINISTRATION Ernest Hawk, M.D. Alma Rodriguez, M.D. Dan Fontaine, J.D. Vice President, Cancer Prevention Vice President, Medical Affairs Executive Vice President, Administration and Head, Division of Cancer Prevention and Chief Financial Officer ad interim Population Sciences Frank Tortorella, J.D. Vice President, Clinical Support Services Chris Belmont Mien-Chie Hung, Ph.D. Vice President and Chief Information Officer Vice President, Basic Science

Brad Gibson Helen Piwnica-Worms, Ph.D. Vice President, Revenue Cycle and Treasurer Vice Provost, Science

Amy Hay George Wilding, M.D. Vice President, Business Development Vice Provost, Clinical and Interdisciplinary Research

Steven Haydon, J.D. Vice President and Chief Legal Officer

Rebecca Kaul Vice President and Chief Innovation Officer

Allyson Kinzel, J.D. Vice President and Chief Compliance Officer

Sherri Magnus Vice President and Chief Audit Officer

Chris McKee Vice President, Business Operations

Spencer Moore Vice President and Chief Facilities Officer

Ferran Prat, Ph.D., J.D. Vice President, Strategic Industry Ventures

Margaret Row, M.D. Vice President, Operations, MD Anderson Cancer Network®

Shibu Varghese Vice President, Human Resources

37 MD Anderson Annual Report

MD ANDERSON CANCER CENTER FACULTY

DIVISION OF ANESTHESIOLOGY, CRITICAL CARE AND PAIN MEDICINE

DIVISION HEAD DEPARTMENT OF CRITICAL CARE AND Carin Hagberg, M.D. RESPIRATORY CARE PROFESSOR AND CHAIR DEPARTMENT OF ANESTHESIOLOGY AND Kristen J. Price, M.D. DIVISION HEAD PERIOPERATIVE MEDICINE DEPARTMENT OF PAIN MEDICINE Carin Hagberg, M.D. PROFESSOR AND CHAIR Tom F. Rahlfs, M.D. PROFESSOR AND CHAIR Salahadin Abdi, M.D., Ph.D.

DIVISION OF CANCER MEDICINE

DIVISION HEAD DEPARTMENT OF GASTROINTESTINAL DEPARTMENT OF NEURO-ONCOLOGY Patrick Hwu, M.D. MEDICAL ONCOLOGY PROFESSOR AND CHAIR AD INTERIM PROFESSOR AND CHAIR John Frederick de Groot, M.D. DEPARTMENT OF BREAST MEDICAL ONCOLOGY James C. Yao, M.D. PROFESSOR AND CHAIR DEPARTMENT OF PALLIATIVE CARE AND Debasish Tripathy, M.D. DEPARTMENT OF INVESTIGATIONAL REHABILITATION MEDICINE DIVISION HEAD CANCER THERAPEUTICS Patrick Hwu, M.D. PROFESSOR AND CHAIR DEPARTMENT OF EXPERIMENTAL THERAPEUTICS PROFESSOR AND CHAIR Eduardo Bruera, M.D. PROFESSOR AND CHAIR AD INTERIM Funda Meric-Bernstam, M.D. Varsha V. Gandhi, Ph.D. DEPARTMENT OF SARCOMA DEPARTMENT OF LEUKEMIA PROFESSOR AND CHAIR DEPARTMENT OF GENERAL ONCOLOGY PROFESSOR AND CHAIR Patrick Hwu, M.D. PROFESSOR AND CHAIR Hagop M. Kantarjian, M.D. Alyssa Rieber, M.D. DEPARTMENT OF STEM CELL TRANSPLANTATION DEPARTMENT OF LYMPHOMA/MYELOMA PROFESSOR AND CHAIR DEPARTMENT OF GENITOURINARY PROFESSOR AND CHAIR AD INTERIM Richard E. Champlin, M.D. MEDICAL ONCOLOGY Robert Orlowski, M.D., Ph.D. PROFESSOR AND CHAIR DEPARTMENT OF THORACIC/HEAD AND NECK Christopher J. Logothetis, M.D. DEPARTMENT OF MELANOMA MEDICAL ONCOLOGY MEDICAL ONCOLOGY PROFESSOR AND CHAIR PROFESSOR AND CHAIR DEPARTMENT OF GENOMIC MEDICINE Patrick Hwu, M.D. John Victor Heymach, M.D., Ph.D. PROFESSOR AND CHAIR Andrew Futreal, Ph.D.

DIVISION OF CANCER PREVENTION AND POPULATION SCIENCES

VICE PRESIDENT AND DIVISION HEAD DEPARTMENT OF CLINICAL CANCER PREVENTION DEPARTMENT OF HEALTH DISPARITIES RESEARCH Ernest Hawk, M.D., M.P.H. PROFESSOR AND CHAIR PROFESSOR AND CHAIR AD INTERIM Powel H. Brown, M.D., Ph.D. Sharon Hermes Giordano, M.D., M.P.H. DEPARTMENT OF BEHAVIORAL SCIENCE DEPARTMENT OF EPIDEMIOLOGY DEPARTMENT OF HEALTH SERVICES RESEARCH VICE PRESIDENT PROFESSOR AND CHAIR AND DIVISION HEAD Paul M. Cinciripini, Ph.D. PROFESSOR AND CHAIR AD INTERIM PROFESSOR AND CHAIR Ernest Hawk, Sanjay Shete, Ph.D. Sharon Hermes Giordano, M.D., M.P.H. M.D., M.P.H.

38 MD ANDERSON FACULTY

DIVISION OF DIAGNOSTIC IMAGING

DIVISION HEAD DEPARTMENT OF DIAGNOSTIC RADIOLOGY DEPARTMENT OF INTERVENTIONAL RADIOLOGY Marshall E. Hicks, M.D. PROFESSOR AND CHAIR PROFESSOR AND CHAIR AD INTERIM Wei Tse Yang, M.D. Sanjay Gupta, M.D. DEPARTMENT OF CANCER SYSTEMS IMAGING DEPARTMENT OF IMAGING PHYSICS DEPARTMENT OF NUCLEAR MEDICINE DIVISION HEAD PROFESSOR AND CHAIR Marshall E. Hicks, M.D. David Piwnica-Worms, M.D., Ph.D. PROFESSOR AND CHAIR PROFESSOR AND CHAIR John D. Hazle, Ph.D. Homer A. Macapinlac, M.D.

DIVISION OF INTERNAL MEDICINE

DIVISION HEAD DEPARTMENT OF GASTROENEROLOGY, DEPARTMENT OF PSYCHIATRY David Tweardy, M.D. HEPATOLOGY AND INFECTUOUS DISEASES PROFESSOR AND CHAIR PROFESSOR AND CHAIR AD INTERIM Alan D. Valentine, M.D. DEPARTMENT OF DERMATOLOGY John R. Stroehlein, M.D. DEPARTMENT OF PULMONARY MEDICINE DIVISION HEAD PROFESSOR AND CHAIR DEPARTMENT OF GENERAL INTERNAL MEDICINE David Tweardy, M.D. Ronald P. Rapini, M.D. PROFESSOR AND CHAIR PROFESSOR AND CHAIR Burton F. Dickey, M.D. DEPARTMENT OF EMERGENCY MEDICINE Carmelita P. Escalante, M.D. PROFESSOR AND CHAIR DEPARTMENT OF SYMPTOM RESEARCH Kumar Alagappan, M.D. DEPARTMENT OF INFECTIOUS DISEASES, PROFESSOR AND CHAIR AD INTERIM INFECTION CONTROL AND EMPLOYEE HEALTH Annemieke Kavelaars, Ph.D., M.S. DEPARTMENT OF ENDOCRINE NEOPLASIA AND PROFESSOR AND CHAIR HORMONAL DISORDERS Issam I. Raad, M.D. PROFESSOR AND CHAIR Steven I. Sherman, M.D.

DIVISION OF NURSING DIVISION OF PATHOLOGY AND LABORATORY MEDICINE

VICE PRESIDENT AND DIVISION HEAD DEPARTMENT OF PATHOLOGY CHIEF NURSING OFFICER Stanley R. Hamilton, M.D. PROFESSOR AND CHAIR Carol Porter, D.N.P. Victor Gerardo Prieto, M.D., Ph.D. DEPARTMENT OF HEMATOPATHOLOGY DEPARTMENT OF NURSING PROFESSOR AND CHAIR DEPARTMENT OF TRANSLATIONAL VICE PRESIDENT AND DIVISION HEAD MOLECULAR PATHOLOGY CHIEF NURSING OFFICER ASSOCIATE PROFESSOR AND CHAIR AD INTERIM Stanley R. Hamilton, M.D. L. Jeffrey Medeiros, M.D. PROFESSOR AND CHAIR Carol Porter, D.N.P. Joyce E. Dains, Dr.P.H., J.D DEPARTMENT OF LABORATORY MEDICINE Ignacio Ivan Wistuba, M.D. PROFESSOR AND CHAIR Elizabeth A. Wagar, M.D.

DIVISION OF PEDIATRICS DIVISION OF RADIATION ONCOLOGY

DIVISION HEAD DIVISION HEAD DEPARTMENT OF RADIATION ONCOLOGY Richard Gorlick, M.D. Stephen Hahn, M.D. PROFESSOR AND CHAIR Stephen Hahn, M.D. DEPARTMENT OF PEDIATRICS DEPARTMENT OF EXPERIMENTAL RADIATION ONCOLOGY DEPARTMENT OF RADIATION PHYSICS DIVISION HEAD PROFESSOR AND CHAIR AD INTERIM DIVISION HEAD PROFESSOR AND CHAIR Richard Gorlick, M.D. Richard Gorlick, M.D. Stephen Hahn, M.D. PROFESSOR AND CHAIR AD INTERIM Junjie Chen, Ph.D. Mary Martel, Ph.D.

39 MD Anderson Annual Report

DIVISION OF SURGERY

DIVISION HEAD DEPARTMENT OF NEUROSURGERY DEPARTMENT OF THORACIC AND Stephen Swisher, M.D. PROFESSOR AND CHAIR CARDIOVASCULAR SURGERY Raymond E. Sawaya, M.D. PROFESSOR AND CHAIR DEPARTMENT OF BREAST SURGICAL ONCOLOGY ARA A. VAPORCIYAN, M.D. DIVISION HEAD PROFESSOR AND CHAIR DEPARTMENT OF ORTHOPEDIC ONCOLOGY Stephen Swisher, M.D. Kelly K. Hunt, M.D. PROFESSOR AND CHAIR DEPARTMENT OF UROLOGY Valerae O. Lewis, M.D. PROFESSOR AND CHAIR DEPARTMENT OF GYNECOLOGIC ONCOLOGY AND Colin P. Dinney, M.D. REPRODUCTIVE MEDICINE DEPARTMENT OF PLASTIC SURGERY PROFESSOR AND CHAIR PROFESSOR AND CHAIR Karen H. Lu, M.D. Charles E Butler, M.D.

DEPARTMENT OF HEAD AND NECK SURGERY DEPARTMENT OF SURGICAL ONCOLOGY PROFESSOR AND CHAIR PROFESSOR AND CHAIR Randal S. Weber, M.D. Jeffrey E. Lee, M.D.

EXTERNAL ADVISORY BOARD MD Anderson’s External Advisory Board is comprised of highly regarded scientific advisors who consult with MD Anderson faculty leaders on research programs and initiatives.

Carolyn “Bo” R. Aldigé Levi A. Garraway, M.D., Ph.D. William G. Nelson, M.D., Ph.D. Prevent Cancer Foundation Eli Lilly and Company Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins David B. Allison, Ph.D. Gad Getz, Ph.D. University of Alabama at Birmingham Broad Institute Giovanni Parmigiani, Ph.D. Harvard School of Public Health Frederick Appelbaum, M.D. Lauren E. Hackett, M.P.A. Dana Farber Cancer Institute Fred Hutchinson Cancer Research Center Vanderbilt-Ingram Cancer Center Antoni Ribas, M.D., Ph.D. Monica Bertagnolli, M.D. Dorothy Hatsukami, Ph.D. UCLA Jonsson Comprehensive Cancer Center Dana-Farber Cancer Institute University of Minnesota Robert Schreiber, Ph.D. Brigham and Women’s Hospital Lee J. Helman, M.D. Washington University School of Medicine Elizabeth Blackburn, Ph.D. Clinical Research Center for Cancer Research, National Institutes of Health Department of Pathology and Immunology Salk Institute Norman E. “Ned” Sharpless, M.D. Paul A. Bunn, Jr., M.D. Lydia Kavraki, Ph.D. Rice University Lineberger Comprehensive Cancer Center, University of Colorado Cancer Center University of North Carolina Quynh-Thu Le, M.D. Steven K. Clinton, M.D., Ph.D. Yang Shi, Ph.D. Stanford School of Medicine The Ohio State University Boston Children’s Hospital David N. Louis, M.D. Graham A. Colditz, M.D., Dr.P.H. Ellen Sigal, Ph.D. Harvard Medical School Washington University School of Medicine Friends of Cancer Research Massachusetts General Hospital Nancy E. Davidson, M.D. David R. Spriggs, M.D. Tak Wah Mak, Ph.D. Seattle Cancer Care Alliance, Memorial Sloan Kettering Cancer Center University of Toronto Fred Hutchinson Cancer Research Center Craig B. Thompson, M.D. Elaine Mardis, Ph.D. University of Washington, Memorial Sloan Kettering Cancer Center The Ohio State University Fred Hutchinson Cancer Research Center Daniel Von Hoff, M.D., F.A.C.P. Monica Morrow, M.D., F.A.C.S. Keith T. Flaherty, M.D. TGen Memorial Sloan Kettering Cancer Center Massachusetts General Hospital Ralph Weissleder, M.D., Ph.D. Harold Moses, M.D. Judy E. Garber, M.D., M.P.H. Massachusetts General Hospital Vanderbilt-Ingram Cancer Center Dana-Farber Cancer Institute Harvard Medical School

40 MD ANDERSON FACULTY

BASIC SCIENCE DEPARTMENTS

RESEARCH DEPARTMENTS DEPARTMENT OF IMMUNOLOGY Helen Piwnica-Worms, Ph.D. PROFESSOR AND CHAIR Vice provost for science James P. Allison, Ph.D.

DEPARTMENT OF BIOINFORMATICS AND DEPARTMENT OF MOLECULAR AND COMPUTATIONAL BIOLOGY CELLULAR ONCOLOGY PROFESSOR AND CHAIR PROFESSOR AND CHAIR John N. Weinstein, M.D., Ph.D. Mien-Chie Hung, Ph.D.

DEPARTMENT OF BIOSTATISTICS DEPARTMENT OF SYSTEMS BIOLOGY PROFESSOR AND CHAIR PROFESSOR AND CHAIR Kim-Anh Do, Ph.D. Gordon B. Mills, M.D., Ph.D.

DEPARTMENT OF VETERINARY MEDICINE DEPARTMENT OF CANCER BIOLOGY AND SURGERY PROFESSOR AND CHAIR PROFESSOR AND CHAIR Raghu Kalluri, M.D., Ph.D. Peggy T. Tinkey, D.V.M.

DEPARTMENT OF EPIGENETICS AND DEPARTMENT OF VETERINARY SCIENCES MOLECULAR CARCINOGENESIS PROFESSOR AND CHAIR PROFESSOR AND CHAIR Christian Abee, D.V.M. Sharon R Dent, Ph.D.

DEPARTMENT OF GENETICS SCHOOL OF HEALTH PROFESSIONS PROFESSOR AND CHAIR PROFESSOR AND DEAN Guillermina Lozano, Ph.D. Shirley Richmond, ED.D.

41 MD Anderson Annual Report

MD Anderson Cancer Center Board of Visitors The MD Anderson Cancer Center Board of Visitors is an appointed board of people committed to helping MD Anderson achieve its mission of eliminating cancer. Board programs emphasize private fund development, public relations and outreach on behalf of the institution.

James J. Mulva Marsha Shields The Honorable Donald L. Evans Melvyn N. Klein Chair Chair Elect Vice Chair Immediate Past Chair

Officers The Honorable James A. Baker, III Mr. Clarence P. Cazalot, Jr. Mrs. Linnet F. Deily Mr. Lee Barberito Mr. Michael J. Cemo Mrs. Patricia Hamilton Dewhurst Mr. James J. Mulva Chair Mr. John W. Barnhill, Jr. Mr. Albert Y. Chao Mr. Jerry Dickman Mrs. Marsha Shields Mr. Michael G. Bartolotta Mr. Tony Chase Mr. Ben A. Donnell Chair Elect Mr. Lawrence E. Bathgate II Ms. Lois Chiles Mr. William J. Doré, Sr. The Honorable Donald L. Evans Mr. Alan R. Batkin* Mr. Arthur Ciocca Mr. Walter W. Driver, Jr. Vice Chair Mr. David J. Beck Mrs. Cindy Citrone Mrs. Jan E. Duncan Mr. Melvyn N. Klein Mr. Paul E. Begala Mr. David A. Cockrell Mr. John H. Duncan, Sr. Immediate Past Chair Mr. Brent Alan Benoit Mr. Ernest H. Cockrell Mr. Raymond A. Eckstein, Jr. Mr. G. Alex Bernhardt, Sr. Mr. Ted Collins, Jr. Mr. Jay S. Eisenberg Members Mrs. Sally B. Berry Mr. Gus H. Comiskey Jr. Mrs. Elizabeth G. Epley Mrs. Linda L. Addison Mrs. Kelli L. Blanton The Honorable Peter R. Coneway Dr. Susan Zane Epstein* Mr. Richard C. Adkerson Mrs. Patricia Bodin Mrs. Anne P. Connally Mrs. Christine Gaylord Everest Dr. Durga D. Agrawal Mr. Giorgio Borlenghi Mr. John B. Connally III Mr. James H. Everest Mrs. Peggy Brunet Ahuja Dr. W. E. Bosarge, Jr. Mr. Rufus Cormier, Jr. Mr. Gregg H. Falgout Mr. Mark W. Albers Mr. Joel Brochstein Mrs. Shirley Coskey Mr. G. Steven Farris Mr. John D. Alexander, Jr. Mr. Robert T. Brockman Mr. Edwin L. Cox Mr. Stephen L. Feinberg Mr. Stanford J. Alexander Mr. Kyle C. Brooks Mrs. Nadine Craddick Mr. Alan D. Feld Mrs. Judy Ley Allen Mr. J. Robert Brown Mrs. Cheryl Creuzot Mr. Dillon J. Ferguson Mrs. Nita Ambani Mr. I. Jon Brumley Mrs. Rose S. Cullen Mr. Jason B. Few Mr. Richard H. Anderson* Mrs. Barbara Bush Mr. William M. Daley* Mr. George A. Finley III Mr. Barry G. Andrews The Honorable George H. W. Bush Mr. Christopher Damico* Mr. William B. Finneran Mr. Glynn Andrews Mr. William R. Bush Mr. James D. Dannenbaum Mrs. Alejandra De la Vega Foster Mr. Matthew Anthony Mr. Charles Butt Mr. Doug Deason* Mrs. Patsy S. Fourticq Mr. James B. Archer* Pastor Kirbyjon H. Caldwell Mr. Alfred L. Deaton III Mr. Steve L. Fox Mr. Andrew M. Baker Mr. Rick J. Calhoon Mrs. Myrna J. Deckert Mr. Michael E. Frazier

* New members 42 PARTNERS IN MAKING CANCER HISTORY

Mr. James L. Gallogly Mr. T. Mark Kelly Mr. Allen A. Meyer Joan Weingarten Schnitzer Mr. Gilbert A. Garcia Mrs. Nancy G. Kinder Mr. Howard M. Meyers Mr. John C. Schweitzer Mrs. Lily C. Garfield Dr. Henry A. Kissinger Mr. Steven L. Miller Mr. Milton L. Scott Mrs. Diane D. Gates Mr. Wyck A. Knox, Jr. Mrs. Kit Moncrief Dr. Thomas Seitz Mr. Wayne Gibbens Mr. David H. Koch Mr. W. A. “Tex” Moncrief, Jr. Mrs. Nancy M. Seliger Mr. Jimmy I. Gibbs Mr. Gregory A. Kozmetsky Mrs. Denise D. Monteleone Mrs. Peggy Sewell Mr. Gary F. Gibson Dr. Demos T. Kyrazis Mr. William C. Montgomery Mr. Marc J. Shapiro Mr. Terry M. Giles Mrs. Julie Kyte Dr. Laura G. Murillo Mr. John H. Shields II Mr. Thomas S. Glanville Ms. Neda Ladjevardian Ms. Martha W. Murphy Mrs. Jan A. Levit Silver Mr. George Y. Gonzalez Mr. Eric S. Lane Mr. Henry G. Musselman Mr. Doyle Simons Dr. Marie Goradia Mrs. Elyse Lanier Mr. Joseph Neubauer Mr. Herbert D. Simons Mr. Steven L. Gordon Mr. Pierre F. Lapeyre, Jr. Mr. W. Robert Nichols III Mr. Donald R. Sinclair Mr. Richard W. Gray III Mr. Stephen A. Lasher Mr. Dennis E. Nixon Mr. Lester H. Smith Mr. F. O’Neil Griffin Mrs. Helen H. Laughery Mr. George E. Norcross III Mr. Walter J. Smith Mr. David M. Grimes II Mr. C. Berdon Lawrence Mr. Marvin Odum Mr. Glenn B. Stearns Mrs. Rosalind Redfern Grover Dr. Charles A. LeMaistre** Mrs. Kay M. Onstead Mrs. Ida Louise Clement Steen Mr. Felo Guerra Ms. Marty V. Leonard Mrs. Pamela K. Onstead Mr. Gary W. Stein Mr. Ben A. Guill Mrs. Mary V. Lester Mr. Paul F. Oreffice Mrs. Lenise Stephenson Mr. Robert G. Gwin Mr. Max S. Levit Mr. Patrick C. Oxford Mr. H. Leighton Steward Mrs. Maureen Hackett Mr. Michael R. Levy Ms. Ebru Ozdemir Mr. Charles W. Stiefel Mrs. Janelle Hail Mr. Michael C. Linn Ms. Ana Palacio Mrs. Gayle B. Stoffel Mrs. Katherine C. Hatcher Mrs. Nancy B. Loeffler Mrs. Vicky M. Pappas Rabbi Alvin M. Sugarman Mr. Lawrence H. Hayward* Ms. Janiece Longoria Mrs. Roseann Park Mr. Sam L. Susser Ms. Adrea D. Heebe Mr. Harry J. Longwell Mrs. Melinda Hill Perrin Mr. Charles W. Tate Mrs. Becky Bradfield Heiser Mr. Angel Losada Mrs. Jan R. Pickens Mr. Mac Tichenor, Jr. Mrs. Gloria Hicks Mr. Jeff B. Love Mr. T. Boone Pickens Mrs. Sue S. Timken Mrs. Mindy Hildebrand Ms. Mary Ralph Lowe Mr. Ralph Ponce de Leon Mr. Robert B. Tudor III Miss Lyda Hill Mrs. Marlene A. Malek Dr. Leslie Rainbolt-Forbes Mr. Tony Vallone Mr. Yerger Hill III Mr. Jed Manocherian Mr. Jack P. Randall Mr. S. Wil VanLoh, Jr. Mr. Jeffrey C. Hines Mr. Rodney H. Margolis Mrs. Ashley Scott Rankin Mr. Steven H. Wasserman Mr. Forrest E. Hoglund Mr. Kade L. Matthews Mrs. Sheila Reese Mr. William M. Webster IV Mr. D. Alter Holand Mrs. Karen R. Matthews Mr. Reynaldo Reza Mr. Herbert D. Weitzman Mr. John A. Holland Mr. L. Lowry Mays Dr. Robert C. Robbins The Honorable Mark White Mrs. Desiree Lyon Howe Mrs. Linda Mays McCaul Ms. Regina J. Rogers Mrs. Margaret Alkek Williams Mr. Woody L. Hunt Mrs. Mary Anne McCloud Mr. William E. Rosenthal Mrs. Michel H. Williams Mrs. Barbara R. Hurwitz Mr. Red McCombs Dr. Alexander Rovt Mrs. Sheridan Williams Mr. Charles E. Hurwitz Mr. Andrew D. McCullough, Jr. Mr. Scott E. Rozzell Mr. John H. Wilson III The Honorable Kay Bailey Hutchison Mrs. Stacie McDavid Mr. Thomas V. Rushing Mr. Melvyn L. Wolff Mrs. Judith Jaynes Mr. Michael D. McKinnon Mrs. Helen Lho Ryu Mr. Don M. Woo The Honorable Brenda L. Johnson Mr. R. Drayton McLane, Jr. Mr. Andrew E. Sabin The Honorable Joseph Zappala Ms. Luci B. Johnson The Honorable Thomas F. McLarty III Mr. Federico Sada Mr. Eric S. Zorn Mr. Tom Johnson Mr. Charles D. McVean Mr. Michael S. Samis Mrs. Glenda R. Kane Mr. Michael J. Medrano Mr. A. R. “Tony” Sanchez, Jr. Mrs. Danielle Kavanagh Mrs. Sonceria Messiah-Jiles Mr. Christopher Sarofim

* New members ** Deceased 43 MD Anderson Annual Report

® Ms. Kim Alfonso Mr. Derek Anderson Partners in Making Cancer History Mr. and Mrs. Vic Alfonso Mr. and Mrs. Gary D. Anderson Albert and Margaret Alkek Foundation Mr. Howard T. Anderson, Jr. MD Anderson gratefully acknowledges the following individuals, foundations, organizations Kristin and Gregory Allemann Mr. James E. Anderson and others who made commitments of $1,000 or more from Sept. 1, 2015, to Aug. 31, 2016. Mr. and Mrs. Curtis L. Allen, Jr. Mr. and Mrs. James F. Anderson Dr. Harold A. Allen and Bertha Allen John Henry and Dora Anderson Mr. Jack V. Allen, Jr. The Honorable and Mrs. John S. Anderson Mr. and Mrs. Joe B. Allen Karen and Charles Anderson Mr. Joseph Allen Mr. and Mrs. Kenneth W. Anderson Mrs. Judy Ley Allen Mr. and Mrs. Marcus A. Anderson Mr. and Mrs. Lemuel Allen, Jr. Mr. and Mrs. Mark Anderson Mr. and Mrs. Marion T. Allen Ms. Martha L. Anderson Mr. Meredith B. Allen Mr. Robert R. Anderson Mrs. Nancy C. Allen Mr. Robert W. Anderson Nick and Barbara Allen Sydney J. Anderson Mr. Robby R. Allen Mr. Thorvin Anderson Dr. and Mrs. Robert Allen Mr. William C. Anderson Mr. and Mrs. William W. Allen Mr. and Mrs. William L. Anderson, Jr. Allen Enterprises, Inc. M. D. Anderson Foundation Rita Allen Foundation Rose-Marie & Jack R. Anderson Foundation Mrs. Catherine C. Alley Mrs. Adele W. Anding Alliance Financial Group Mr. and Mrs. Gilbert H. Andres The Alliance for Clinical Trials in Oncology Mr. and Mrs. Barry G. Andrews Mr. and Mrs. Pierce M. Allman Mr. Glynn Andrews Almeda Holdings Mr. Joseph J. Andrews Mr. and Mrs. Joseph Alonzi Mr. and Mrs. Richard L. Andrews Mr. Arthur J. Alper Andrews Distributing of North Texas, Ltd. Mr. and Mrs. Jim Alsup Glynn Andrews Family Foundation Mr. and Mrs. Fahad Al-Tamimi Andrews Foundation Altec/Styslinger Foundation A. W. and Suan Angelo Foundation Altman Goldstein Foundation Angie’s Spa Cancer Foundation Mr. and Mrs. Anthony Altmann Kelley and Michael Annino Mr. Carlos Alvarez Anonymous Amarillo Area Foundation The Honorable and Mrs. Hushang Ansary American Academy of Neurology Institute Mrs. Joyce A. Antes American Alloy Steel, Inc. and A. J. Moore Mr. and Mrs. Matthew Anthony American Association for Cancer Research Ms. Samuel Ella Antoine Ronald DePinho, M.D., MD Anderson’s fourth full-time president, officially announced the creation of the Beau Biden Chair American Association of Neurosurgeons Mr. Charles Anzek for Brain Cancer Research at the 75th anniversary gala. W.K. Alfred Yung, M.D., who served as Biden’s doctor, presented a American Bank, N.A. Aon Foundation commemorative memento to Dr. Jill Biden and Vice President Joe Biden. American Board of OB/Gyn Educational Apache Corporation Foundation Mr. Ronald H. Apel American Borate Company Aplastic Anemia & MDS International 5 Sisters Inc. Mr. and Mrs. Irwin B. Ackerman Affiliated Solutions LLC American Brachytherapy Society Foundation, Inc. 38th Street Pharmacy, Inc. Mr. Michael Ackerman Aflac American Cancer Society Ms. Roberta K. Apolant and Mr. David Duerr Mr. and Mrs. Richard Acosta Mrs. Sushila Agrawal and Dr. Durga D. Agrawal The American Endowment Foundation Dr. and Mrs. Bruce S. Appelbaum A Acosta Management, Inc. Mr. Dominic Ahearn American Legion Post 208 Apple Corporation Dr. Kenneth S. Adam and Ms. Gayle Goodman Mr. and Mrs. David Ahlquist The American Lung Association National Applied Petroleum Technologies Mr. and Mrs. Albert T. Adams Mr. and Mrs. Avinash C. Ahuja A & A Cattle Company American Society of Colon and Rectal Arbella Charitable Foundation, Inc. Estate of Alvin F. Adams Ms. Dana Aichler A. E. Machine Works, Inc. Surgeons Mr. Harlan T. Archer Mr. and Mrs. Brian D. Adams Mr. Daniel G. Aiken A G Equipment Company American Society of Health-System Mr. Scott W. Archer Mr. and Mrs. James E. Adams AIM at Melanoma Foundation Pharmacists Research and Education Carol and Steve Aaron James B. & Lois R. Archer Charitable Mr. Kevin D. Adams Mr. Jamal Akhtar Foundation Mrs. Karen S. Abbott Foundation Mr. and Mrs. Noel T. Adams Mr. Barry Albano American Society of Hematology Abbrigen Inc. Ms. Elizabeth A. Ardito ADB Airfield Solutions The Albany Foundation American Steel & Aluminum Company Dr. and Mrs. Christian R. Abee Ardmore Institute of Health Mrs. Patricia N. Adcock Albemarle Foundation American-Italian Cancer Foundation Maky and Carlos Abello Mrs. Bonnie Ardoin Mr. Terence E. Adderley Mr. and Mrs. Mark W. Albers America’s Charities Mr. Richard R. Abello Mr. and Mrs. George E. Ardoin Addi’s Faith Foundation Dr. and Mrs. Todd J. Albert Mr. William Amerman Ms. Barb Abernethy Mr. and Mrs. Greg Ardoin Mr. and Mrs. Kevin L. Adds The Leo and Anne Albert Institute for Bladder Amgen, Inc. Dorothy and Mickey Ables Dr. Van Ardoin and Mrs. Cynthia Ardoin Dr. Miriam and Sheldon G. Adelson Medical Cancer Care and Research Mr. Dan T. Amis Mr. Benjamin P. Abney The Arena Energy Foundation Research Foundation Mrs. Joyce Albrecht Mr. and Mrs. Robert C. Ammann III Mr. Bruce A. Argetsinger Mr. Peter Aboytes Mr. and Mrs. Gerhard P. Adenacker Ms. Patrice Alessandra The Homer Ammann Trust Dr. Susan C. Abraham ARIAD Pharmaceuticals, Inc. Adenoid Cystic Carcinoma Research Charles Alexander and LaVerne Alexander Mr. Jack W. Amschwand Arkansas Community Foundation Mr. and Mrs. Gary M. Abramson Foundation Joan and Stanford Alexander Amschwand Sarcoma Cancer Foundation Ms. Kathleen Abshire Mr. and Mrs. Charles F. Armbrust Ms. Mildred C. Adicks Mr. and Mrs. John D. Alexander, Jr. Anadarko Petroleum Corporation Mr. and Mrs. David S. Armbruster Abundant Living Faith Center Church, Inc. Mrs. Rose Adkison Jerri and Jim Alexander Endowment for Cancer Mr. and Mrs. Curtis V. Anastasio Acelity Corporation Dan and Mary Armour Mr. and Mrs. Jim S. Adler Research Anatom-E XRT Information Systems Ltd. Mr. and Mrs. Lester Armour III Achillion Pharmaceuticals, Inc. Advance Medical, Inc. Mr. Steven R. Alferi Mr. Byron H. Anderson Mr. and Mrs. Robert G. Ackerley Armour Trust

44 PARTNERS IN MAKING CANCER HISTORY

Mr. Dale E. Armstrong Baddour Family Foundation Inc. Mr. and Mrs. Kenneth J. Barr Mr. and Mrs. Brett Beardsley Mr. Richard Bennett Mr. Bruce P. Arnett, Jr. Mr. Alan P. Baden The Kenneth J. and Cora Barr Foundation Mr. and Mrs. Robert H. Beavers Mr. and Mrs. Brent Alan Benoit Mr. and Mrs. Daniel C. Arnold Mr. and Mrs. Robert M. Baer Ms. Colleen C. Barrett Bechtel Employees Club of Houston Mr. Jon E. Benson Laura and John Arnold Mr. and Mrs. Randy Baetz Michael Barrett Mr. and Mrs. David J. Beck Mr. Edmond B. Bentley Mr. and Mrs. Truman Arnold Mr. and Mrs. David Baggett Mr. Ryan Barrett Dr. and Mrs. Edward Beck Bentley & Associates, P.C. Arnold Foundation Mrs. Barbara Conway Bailey Barriere Construction Co., L.L.C. Mr. Robert Beck Mrs. Bette V. Benton Truman and Anita Arnold Foundation Mr. George Bailey, Jr. Mr. and Mrs. James Barrow Sharon and John Beck Mr. Brian K. Berg Mr. and Mrs. Robert B. Arnot Mrs. Margaret C. Bailey Mr. and Mrs. Linda and Tommy Barrow Beck Bros., Inc. Mr. and Mrs. John E. Bergeron, Jr. Arnot Oil Company, LLC Mr. Robert Baillargeon Mr. John Barry Mr. and Mrs. Harry G. Beckner Mr. and Mrs. Steve Bergstrom Mr. and Mrs. Sandy P. Aron Mr. Thomas B. Baird Clint Barsch Foundation Dr. and Mrs. Samuel Bederman Bergstrom Family Foundation Ms. Rachel Arredondo Dr. Joseph S. Bak Bartlesville Community Foundation Mr. and Mrs. William W. Bedford Mr. Lloyd Berhoff Mr. Zane W. Arrott Mr. and Mrs. Alan A. Baker Sally and Jim Bartlett Mr. and Mrs. Elton G. Beebe Howard and Wendy Berk Lovee and Bob Arum Mr. and Mrs. Andrew M. Baker Mr. and Mrs. Michael G. Bartolotta Mr. and Mrs. John T. Beecherl Mr. Matthew Berki Mr. and Mrs. Vijay K. Arya Mr. and Mrs. B. Robert Baker, Jr. Mr. Terry Basehore Mr. and Mrs. Louis A. Beecherl, III Mr. Brian Berkle Mr. H. G. Ash Mr. and Mrs. Bradford N. Baker Mr. and Mrs. Jim Basil Mrs. Linda Beek Mr. Christopher J. Berman The H. G. Ash Foundation Mr. and Mrs. Darrel P. Baker Mrs. Mercedes Bass Mr. David C. Beeman Mr. and Mrs. G. Alex Bernhardt, Sr. Mr. and Mrs. John K. Ashby Mrs. Dusty Baker Bass Energy Company Tom and Janet Behanick Bernhardt Design Ashley Collins Studios Mr. Gary J. Baker Mrs. Suzanne S. Bassett JoAnna and Robert Behl Ms. Cathy E. Bernier Kelly D. Ashmead Mr. James Baker Dr. and Mrs. Robert C. Bast, Jr. Mrs. Marie E. Behrle Mr. and Mrs. Frank V. Bernobich AT&T Mr. and Mrs. James A. Baker, III John and Nellie Bastien Memorial Foundation Mr. and Mrs. Brent R. Behrman Dr. and Mrs. Michael M. Berns Employees of AT&T Estate of Lamar Robert Baker, Jr. Ms. Julie A. Bateman Martin and Kathleen Beirne Mr. and Mrs. Howard Bernstein AT&T Political Action Committee Mr. Lewis T. Baker, Jr. Mr. and Mrs. Bruce B. Bates Mr. and Mrs. William H. Belden, Jr. Mrs. Jayusia P. Bernstein Dr. Russell P. Atchley Estate of Renza Moscatelli Baker Mr. Gus Bates III Mr. Harley D. Belew Mr. and Mrs. Buford P. Berry Mrs. Nancy B. Atha Mr. Robert A. Baker Jane and Alan Batkin Mr. and Mrs. Robert A. Belfer Mr. Hugh C. Berry, Jr. Mr. and Mrs. John S. Atherton Mr. and Mrs. Robert H. Baker Baton Rouge Area Foundation Robert A. and Renée E. Belfer Foundation Mr. and Mrs. William B. Berry Ms. Christie Atkerson Baker Botts L.L.P. Mr. Joseph E. Batson, Jr. Mrs. Billie B. Bell Mr. and Mrs. Stephen W. Bershad Mrs. Eugenia M. Atkins Baker Hughes Foundation Mr. and Mrs. James A. Baudin Mr. and Mrs. Brian M. Bell Mr. Clarence Bertrand Atlas General Agency, LLC Bakers Sign & Manufacturing Inc. Mr. and Mrs. A. Glenn Bauguss, Jr. Mr. and Mrs. Brad Bellah Bessemer Trust Mr. and Mrs. Douglas C. Atnipp Mrs. Jodi Bakes Mr. and Mrs. Eddy Bauman Mr. Ray L. Bellande Bethyl Laboratories, Inc. Mr. Kim Attaya Mrs. Deborah A. Bakewell Ms. Annell R. Bay and Mr. Robert Suchecki Mr. and Mrs. James Bellinger, Jr. Dr. and Mrs. Elmo M. Beyer, Jr. Atwood Oceanics Mr. Vincent C. Baldasare Dr. Roberto J. Bayardo Mrs. Joan S. Bellinger Mr. William E. Bezanson Dr. Michelle Aucoin and Dr. B. Michael Aucoin Jerry and Emy Lou Baldridge Mr. Gary R. Bayer Mr. and Mrs. John W. Bellinger Mr. and Mrs. Ravi S. Bhatia Dr. and Mrs. Arthur I. Auer Mr. Steven L. Balfe Mr. and Mrs. Walter S. Bazarsky Ms. Yvonne M. Bellinger Mr. and Mrs. Fred B. Bialek Wayne B. and Jeanette K. Aurich Mr. and Mrs. Robert C. Balfour III Employees of BBVA Compass Mr. and Mrs. David S. Bellows Mr. Richard H. Bickerstaff, Jr. Ms. Rebecca Austen Mr. and Mrs. George L. Ball BCM & Associates, Inc. Mr. and Mrs. Steve Belt Mr. William M. Biddison Mr. Gene Austin Mr. John G. Ball Be The Difference Foundation Mr. Gonzalo Beltran Wayne and Caroline Bienvenu Austin Community Foundation Mr. Bruce K. Ballard Mr. and Mrs. Bill Beach Belvedere Trading Mrs. Diane Bigelow Australia and New Zealand Melanoma Trials Ms. Cynthia Ballas Mrs. William N. Beach Ms. Carol K. Belvedresi Mr. and Mrs. Thomas J. Billings Group Ms. Francys A. Ballenger Karen and Spencer Beal Ben E. Keith Company Mr. and Mrs. David Frederic Bingham Autobahn Motorcar Group Estate of James R. Ballinger Mr. and Mrs. David S. Beall Benefit Concepts, Inc. Biocartis NV Mrs. Rachel Cruz Auwarter and Mr. Todd Mr. and Mrs. Joseph Balusik Mr. and Mrs. Michael A. Beam Ms. Michelle M. Bengue and Mr. Lawrence E. BioMedical Solutions Inc. Auwarter Mr. and Mrs. P. Banavalkar Ms. Sharon K. Beaman Bathgate II BIP Inc. Avalon Risk Management Insurance Bancorp Investments, Inc. Mr. Robert H. Bean Mr. and Mrs. David Benjamin Stephen and Mary Birch Foundation, Inc. Agency, LLC Mr. Mark Bandy Mr. and Mrs. M. Stephen Beard Dr. and Mrs. Robert S. Benjamin Mr. and Mrs. Carl Bird Mr. and Mrs. James Avery Bank of America Corporation Dr. and Mrs. Andrew Avillo Employees of Bank of America Corporation AVJ Foundation Bank of America Foundation Avon Foundation for Women Endowed Distinguished University Chairs Bank of America Philanthropic Management Mr. Kenneth R. Awad Mrs. Barbara Banker Mr. and Mrs. Robert R. Awe HARRY CAROTHERS WIESS DISTINGUISHED UNIVERSITY CHAIR SAMSUNG DISTINGUISHED UNIVERSITY CHAIR Mrs. Hugh A. Bankhead Mr. Allen L. Aycox FOR CANCER RESEARCH IN CANCER MEDICINE Mr. and Mrs. R. Clifford Banks Estate of Donna M. Ayers Robert C. Bast Jr., M.D. Hagop Kantarjian, M.D. Mrs. Michelle Banton Dr. and Mrs. Robert C. Ayers, Jr. Mr. and Mrs. Lee Barberito OLGA KEITH AND HARRY CAROTHERS WIESS DISTINGUISHED SHEIKH KHALIFA BIN ZAYED AL NAHYAN DISTINGUISHED Lawson Ayo Mr. Gregory R. Barbosa UNIVERSITY CHAIR IN CANCER RESEARCH UNIVERSITY CHAIR IN CANCER RESEARCH Dr. and Mrs. Jamil Azzam Mr. and Mrs. Larry G. Barbour Charlotte and Jamil Azzam Foundation Ethan Dmitrovsky, M.D. Anirban Maitra, M.B.B.S. Ms. Tracey S. Barclay Mr. and Mrs. John N. Barineau III THE ROBERT A. WELCH DISTINGUISHED UNIVERSITY CHAIR OLGA KEITH WIESS DISTINGUISHED UNIVERSITY CHAIR B John and Lee Barker IN CHEMISTRY FOR CANCER RESEARCH Estate of Bruce A. Barkhurst Andrew Futreal, Ph.D. Gordon B. Mills, M.D., Ph.D. B & B Foundation Mr. and Mrs. Leroy R. Barnes, Jr. FREDERICK F. BECKER DISTINGUISHED UNIVERSITY CHAIR THE JOHN BROOKS WILLIAMS AND ELIZABETH WILLIAMS B & B Iron & Metal Co., Inc. Mr. Vess Barnes III B. P. Newman Investment Co. The Barnett Family Foundation FOR CANCER RESEARCH DISTINGUISHED UNIVERSITY CHAIR IN CANCER MEDICINE Mr. and Mrs. Ralph W. Babb, Jr. Mr. James C. Barnette Stanley R. Hamilton, M.D. Randal S. Weber, M.D. John and Jo Babbitt Barney Family Foundation SHEIKH MOHAMED BIN ZAYED AL NAHYAN DISTINGUISHED SHEIKH ZAYED BIN SULTAN AL NAHYAN DISTINGUISHED Ms. Melinda Bachelor Mr. and Mrs. Steven J. Baron UNIVERSITY CHAIR IN CANCER RESEARCH UNIVERSITY CHAIR OF MEDICAL ONCOLOGY Mr. Cecil F. Backus, Jr. Mr. Donald Barr Patrick Hwu, M.D. Robert A. Wolff, M.D. Dr. Raymond J. Baddour Dr. and Mrs. F. T. Barr

As of Sept. 1, 2016 45 MD Anderson Annual Report

Mr. Edwin A. Birdwell Mr. and Mrs. Frank Blakley Blum-Kovler Foundation/Judy and Peter Blum Ms. Mary Bond Mr. and Mrs. Chase Boswell Mr. Frank M. Bireley Mr. and Mrs. Myron G. Blalock III Kovler Mr. and Mrs. Gordon Bonfield Mr. and Mrs. Winston F. Bott, Jr. B.I.S.H. Foundation Mr. Antoine Blanchard BNY Mellon Community Partnership Estate of Frank J. Bonitati Mr. and Mrs. Don A. Boudreaux David and Nancy Bishop Blank Rome LLP Mrs. Evelyn V. Boake Ms. Donna Pace Bonner Mr. and Mrs. Jay B. Boudreaux Mr. Jim B. Bishop Mr. and Mrs. Ron Blankenship Edwin L. and Carla M. Boardman Mr. and Mrs. E. V. Bonner, Jr. Mr. and Mrs. E. H. Boullioun, Jr. Kathy and Gene Bishop Mr. and Mrs. Eddy S. Blanton Boardwalk Pipeline Partners Mrs. Jeanie P. Bonner Mr. and Mrs. Lynn L. Bourdon III Mr. David Biwer Mr. and Mrs. Jack S. Blanton, Jr. Ms. Sherri Boatwright Henry and Pamela Bonura Foundation Mr. and Mrs. Gregory Bourland BKCW Insurance Agency Mrs. Virginia Renfroe Blanton Bob Grimmer Electric, Inc. Mr. Terry L. Booker Mr. and Mrs. Douglas J. Bourne Mr. Chris Black Blessing American Legion Auxiliary No. 649 Mr. and Mrs. William R. Bobbora Ms. Sheryl J. Bookman Ann and André Boutté Mr. and Mrs. Dan P. Black Mr. and Mrs. Robert L. Blevins, Jr. Mr. and Mrs. Fredrich Boden Mr. and Mrs. James A. Boone Mrs. Doris E. Bouwensch James L. and Doris Black Mr. and Mrs. Kenneth Blewett Mr. Philip L. Boehk Ms. Patsy H. Boone Bowen, Miclette & Britt, Inc. Dr. Karen Black and Dr. Jim J. Black Mr. and Mrs. Steven R. Block Linda and Dick Boettcher Booster U. S. S. Theresa Bowers Revocable Trust Mr. and Mrs. Van Lear Black III Mr. John Blome Ms. Martha Boettcher Boot Barn Mr. Clark G. Boyce, Jr. Black Foundation Ms. Joanne Bloom Susan and Dan Boggio Mr. and Mrs. I. M. Booth Robert and Julia Boyce BlackArch Partners Mike and Lori Bloomfield Betsy C. Bolin Mrs. Amy Lizbeth Boquist Mr. Doug Boyd Mr. Gary W. Blackie Mr. Michael A. Blue Ms. Andrea H. Bollinger and Mr. Jacob A. Mr. and Mrs. Raymond Bordelon Mrs. Lavinia P. Boyd Susan Poorman Blackie Ovarian Cancer Blue Bell Creameries Giardina Border Equipment Sales, LLC Mrs. Patricia K. Boyd Foundation Blue Grass Community Foundation Mr. Brandon Bollinger Mr. and Mrs. John Borders Dr. Liam Boyle Blackrock, Inc. Bluebonnet Electric Cooperative, Inc. Mr. and Mrs. Michael J. Bolner The Kenneth E. Boring Charitable Foundation, Ms. Sherri Boyter The Blackwell Foundation Mr. and Mrs. Edwin A. Bluestein, Jr. Mr. and Mrs. Farhad Bolourchi Inc. BP Foundation, Inc. Mr. and Mrs. Donald G. Blair Bluff Creek Ranch Company Dr. and Mrs. James L. Bolton Mr. and Mrs. Giorgio Borlenghi Ms. Billye B. Bradley Mr. and Mrs. Larry W. Blair In Memory of Linda Blum Ms. Giovanna R. Bonanno and Mr. James Scott Mr. and Mrs. Douglas Bostrom Mr. and Mrs. Francis R. Bradley Cargile Katherine K. Blake Mr. Robert I. Blum Mrs. Joy Bostrom Mr. and Mrs. Jeff S. Bradley Estate of Aleck C. Bond Mr. Kendrick F. Bradley Mr. and Mrs. Thomas Bradley Endowed Distinguished Chairs Maria and Patrick Brady Braly Family Limited Partnership VIVIAN L. SMITH DISTINGUISHED CHAIR IN LEVIT FAMILY DISTINGUISHED CHAIR IN DIAGNOSTIC BARNTS FAMILY DISTINGUISHED CHAIR FOR Branch Banking and Trust Company Ms. Nancy Brand IMMUNOLOGY IMAGING IN HONOR OF DR. SIDNEY WALLACE CANCER RESEARCH The Norman Paul Brandstatt Revocable Trust James P. Allison, Ph.D. Marshall E. Hicks, M.D. William K. Plunkett, Jr., Ph.D. Mr. and Mrs. Tom Brandt JOHN CHARLES CAIN DISTINGUISHED CHAIR IN RUTH LEGETT JONES DISTINGUISHED CHAIR BUD JOHNSON CLINICAL DISTINGUISHED CHAIR Mr. and Mrs. James J. Braniff III CANCER PREVENTION Mien-Chie Hung, Ph.D. Jack A. Roth, M.D. Mr. John Braniff, Jr. Powel H. Brown, M.D., Ph.D. Mr. Paul A. Branum OLLA S. STRIBLING DISTINGUISHED CHAIR FOR ANNE C. BROOKS AND ANTHONY D. BULLOCK III Mr. Kenneth L. Brasel HUBERT L. AND OLIVE STRINGER DISTINGUISHED CHAIR CANCER RESEARCH DISTINGUISHED CHAIR IN NEUROSURGERY Mr. and Mrs. Fred Braselton IN ONCOLOGY IN HONOR OF SUE GRIBBLE STRINGER Raghu K. Kalluri, M.D., Ph.D. Raymond Sawaya, M.D. Mr. and Mrs. Arthur J. Brass Thomas A. Buchholz, M.D. Mr. and Mrs. Douglas K. Bratton MARY V. AND JOHN A. REILLY DISTINGUISHED CHAIR CHARLES A. LEMAISTRE DISTINGUISHED CHAIR IN Bratton Family Foundation PAMELA AND WAYNE GARRISON DISTINGUISHED CHAIR Eugenie S. Kleinerman, M.D. THORACIC ONCOLOGY, GIVEN BY W. A. “TEX” AND Mr. and Mrs. Kenneth C. Braud IN CANCER RESEARCH DEBORAH MONCRIEF, JR. W. T. AND LOUISE JARRETT MORAN DISTINGUISHED Mr. and Mrs. Alexander M. Brauer Junjie Chen, Ph.D. Stephen G. Swisher, M.D. CHAIR IN PEDIATRIC ONCOLOGY Breast Cancer Research Foundation Mr. Ward Breaux JANE AND JOHN JUSTIN DISTINGUISHED CHAIR IN Shulin Li, Ph.D. THE ROBERT A. WELCH DISTINGUISHED CHAIR Mr. and Mrs. Brad M. Brechtel LEUKEMIA RESEARCH IN HONOR OF DR. ELIHU ESTEY IN CHEMISTRY ROY M. AND PHYLLIS GOUGH HUFFINGTON CLINICAL Mr. Erich E. Bredl Jorge E. Cortes, M.D. John A. Tainer, Ph.D. RESEARCH DISTINGUISHED CHAIR IN UROLOGIC Mr. and Mrs. Daniel L. Breeding NATHAN W. LASSITER DISTINGUISHED CHAIR ONCOLOGY JOAN AND STANFORD ALEXANDER DISTINGUISHED Ms. Linda L. Breihan IN UROLOGY Christopher J. Logothetis, M.D. CHAIR FOR PROSTATE CANCER RESEARCH Dr. Katherine Lay Breiter and Dr. Eric Breiter Mr. and Mrs. Raymond Brekke Bogdan A. Czerniak, M.D., Ph.D. Timothy Thompson, Ph.D. LOCKTON DISTINGUISHED CHAIR IN PANCREATIC Mr. and Mrs. John Brennan W. A. “TEX” AND DEBORAH MONCRIEF, JR. CANCER RESEARCH ROBERT D. MORETON DISTINGUISHED CHAIR IN Mrs. Anne R. Brennan-Hooser and Mr. Gregory DISTINGUISHED CHAIR IN UROLOGY Craig Logsdon, Ph.D. DIAGNOSTIC RADIOLOGY, GIVEN BY W. A. “TEX” AND Hooser Colin P. N. Dinney, M.D. DEBORAH MONCRIEF, JR. Mr. Peter Breunig J. TAYLOR WHARTON, M.D., DISTINGUISHED CHAIR IN Mr. Joe L. Brewton Wei Tse Yang, M.D. WAUN KI HONG DISTINGUISHED CHAIR IN GYNECOLOGIC ONCOLOGY Ms. Stefanie Breyer TRANSLATIONAL ONCOLOGY Karen H. Lu, M.D. ELLEN F. KNISELY DISTINGUISHED CHAIR IN Mrs. Sara Brice Elizabeth A. Grimm, Ph.D. COLON CANCER RESEARCH Mr. and Mrs. Thomas K. Brichford JOHN S. DUNN DISTINGUISHED CHAIR IN James Yao, M.D. Mr. Richard W. Brietzke GILBERT H. FLETCHER MEMORIAL DISTINGUISHED CHAIR DIAGNOSTIC IMAGING Mr. John Blakemore Briggs Stephen Hahn, M.D. William A. Murphy, Jr., M.D. HUBERT L. AND OLIVE STRINGER DISTINGUISHED CHAIR Mr. and Mrs. Phillip Briggs IN BASIC SCIENCE IN HONOR OF SALLY STRINGER Mr. Robert A. Briggs, Jr. EVELYN AND SOL RUBENSTEIN DISTINGUISHED CHAIR GERALD DEWEY DODD, JR. DISTINGUISHED CHAIR IN Dihua Yu, M.D., Ph.D. Mr. and Mrs. Ronald P. Briggs FOR THE CANCER PREVENTION DEPARTMENT DIAGNOSTIC IMAGING Briggs & Veselka Co., P.C. Samir Hanash, M.D., Ph.D. David Piwnica-Worms, M.D., Ph.D. The Ronnie and Gwen Briggs Foundation BOONE PICKENS DISTINGUISHED CHAIR FOR EARLY SENATOR A. M. AIKIN, JR. DISTINGUISHED CHAIR As of Sept. 1, 2016 Mr. and Mrs. Bennie Brigham PREVENTION OF CANCER Helen M. Piwnica-Worms, Ph.D. Mr. and Mrs. Michael D. Brill Ernest Hawk, M.D. Mr. and Mrs. David Brink

46 PARTNERS IN MAKING CANCER HISTORY

Dr. and Mrs. William R. Brinkley The Brunetti Foundation Mrs. Cynthia Buttram Mr. and Mrs. Mark S. Carnes The Chaplaincy Fund, Inc. Mr. and Mrs. David A. Bristol, Jr. Donna and Robert Bruni Mr. Leon G. Byerley, Jr. Mr. and Mrs. Charles E. Carpenter Mr. and Mrs. Alexander J. Chapman Mr. and Mrs. B. Daryl Bristow Colonel Michael A. Brunsvold Mr. and Mrs. George T. Byers Mr. and Mrs. Don Carpenter Gayla C. Chapman and George C. Chapman Ms. Karen L. Brittain Mr. and Mrs. Jonathan B. Bruser Mr. and Mrs. Mike Byers Mr. and Mrs. William A. Carpenter, Jr. Mrs. Louise G. Chapman Mr. Ted Britton Mrs. David D. Bruton, Jr. Valerie and Michael Bynum The Carrig Family Mr. Patrick W. Chapman Ms. Jamie Broach and Mr. Jeff S. Byrd Mr. and Mrs. Charles J. Bryan Mr. Gerald R. Byrd Mr. and Mrs. Al J. Carrion Mrs. Rebecca Chapman The Broach Foundation for Brain Cancer Ms. Nancy Bryan Mr. Lance Byrd Mr. Daniel J. Carroll H.A. and Mary K. Chapman Charitable Research Ms. Peggy L. Bryant Mr. and Mrs. John J. Byrnes SGM. and Mrs. James T. Carroll Foundations Mr. and Mrs. Joel Brochstein Mr. Ray Brysch Mr. and Mrs. James E. Byrns Mr. Jody Carroll Mr. and Mrs. O. Don Chapoton Raymond and Susan Brochstein Mr. Robert Thomas Buchanan Mr. and Mrs. Don V. Carruth Chardan Capital Markets, LLC Mr. and Mrs. John B. Brock III Mrs. Laura L. Bucholz Mr. and Mrs. Richard A. Carruth Charles Schwab Corporation Sophia and G. W. Brock The Helen R. Buck Foundation C Ms. Susan B. Carruthers Mrs. Tanitra Charnsangavej Mr. Jerome S. Broder Buckeye Partners, L.P. Mr. James B. Carson, Jr. Mr. and Mrs. Ricky H. Chastain C.H. Guenther & Son, Inc. Ms. Judith A. Brodkin Ms. Carol M. Buckley Carson Sarcoma Foundation Mrs. Lorena J. Chavis Burt and Hermys Cabanas Peter and Karen Brohn Mr. Richard Buckley Mr. Jeffrey A. Carter Mr. and Mrs. Charles E. Cheever, Jr. Mr. and Mrs. Joseph A. Cabaniss Mr. David S. Brollier Mr. W. P. Buckthal Mr. Larry W. Carter Mr. George L. Chelius Cabot Oil & Gas Corporation Ms. Emily S. Bronstein Mr. and Mrs. Jimmie A. Bufkin W Michael Carter Mr. and Mrs. James Michael Chennault Mr. Frederick Cagle Mr. Austin R. Brooks Vinh X. Bui Mr. and Mrs. Gary J. Cartright Mr. and Mrs. C. Dan Chenoweth Ms. Kristyn Cain Mrs. Carla P. Brooks Mr. and Mrs. William T. Buida Mr. and Mrs. Henry Carwile Ms. Jolene Cherry The Cain Foundation Ms. Diane L. Brooks Dr. Rosaria A. Bulgarella Ms. D. Casas Mr. and Mrs. Faris F. Chesley Mr. Joe Calcaterra, Jr. Estate of Eleine H. Brooks Dr. Robert Bulger Mr. Americo Cascella Mr. and Mrs. Joel Chess Mr. and Mrs. Charles W. Caldwell Mr. and Mrs. Garnett T. Brooks Bull Shirts - Rod Ryan Cares Mr. Keith Casey Chevron Humankind Mr. and Mrs. Dalton L. Caldwell, Jr. Mr. and Mrs. Tim Brookshire Bulldog Club of America - Division IV Mr. and Mrs. Stephen H. Casey Chevron Phillips Chemical Co. LP Mr. John Caldwell Mr. Tom C. Brookshire Mrs. Doris Bullock Mr. Roger Cash The Chicago Community Foundation Mr. John R. Caldwell Mrs. Carolyn ZeBrack Brophy Mr. James R. Bullock, Jr. Mr. and Mrs. S. D. Cashat Mr. and Mrs. Craig P. Chick Mr. and Mrs. Lee Caldwell Mr. and Mrs. Thomas J. Brorby Ms. Sherry W. Bullock Mr. Phillip Cashion Mr. Brian D. Childress California Community Foundation Mrs. Kay Brotherton Mr. Stephen S. Bullock Mrs. Josephine C. Cassata Mr. and Mrs. William C. Childs Mr. and Mrs. Dean Lynn Callender Mrs. Charles Broudy Mr. and Mrs. Dean L. Buntrock Mr. Gabriel C. Castillo Lois Chiles and Richard Gilder Billy and Verline Calley Mr. and Mrs. Scott N. Broudy Burberry Americas John H. and Dorothy M. Castle Charitable Lead Mr. and Mrs. William E. Chiles Cambrian Consultants America, Inc. Mr. Carroll W. Broussard Burberry - Galleria Annuity Trust Dr. Lynda Chin and Dr. Ronald A. DePinho Cameron International Corporation Ms. Cynthia R. Broussard Mr. and Mrs. Joe Tom Burch Mr. Reynaldo Castro, Jr. China Medical University and Hospital Ms. Dawn Camp Broussard & Kay, L.L.C. Penny Burck Mr. and Mrs. Robert B. Caswell Mr. William J. Ching Mrs. Brenda L. Campbell Ms. Alice Brown and Mr. Bruce H. Harkness Mr. and Mrs. C. Scott Burford Mr. and Mrs. John F. Cates, Jr. Mr. and Mrs. Sherman S. Chiu Elena and Bob Brown Ms. Eileen M. Campbell and Mr. Douglas D. Linda and Conley Cathey Mr. Donald D. Chizk, Sr. Mr. and Mrs. Thomas V. Burford Perley Mr. and Mrs. Dale Brown The Catholic Foundation Mr. Charles Cho Mr. and Mrs. David R. Burgess Mr. G. Anthony Campbell David and Janna Brown Mr. and Mrs. Earl D. Catlett Ms. Ernestine B. Choate Mr. Jerry Burgess Mr. and Mrs. R. Trent Campbell, Jr. Mr. Derrick Brown Cauble Sportswear, Inc. Choose Hope, Inc. Ms. Alice L. Burguieres Mr. and Mrs. Robert S. Campbell Mr. and Mrs. Don J. Brown Mr. and Mrs. Charles Causey Mr. and Mrs. Colin C. Chopin Philip Burguieres Mr. Tim Campbell Mr. and Mrs. Gordon H. Brown, Jr. Hershell and Cynthia Cavin David A. and Mary Jo Christensen Mr. Arthur I. Burke, Jr. Canali Trading LLC Mr. Isaac Brown Mr. Sealy H. Cavin Mr. Gary L. Christian Mr. and Mrs. Stephen W. Burke Mr. and Mrs. Denney Cancelmo Mr. and Mrs. James D. Brown Mr. Andrew Caylor Mrs. Melodie M. Christian Tom and Cathy Burke Cancer Kicks, Inc. Mr. Jim Brown Ann and Clarence Cazalot Mr. and Mrs. Terry Christie Mr. and Mrs. William A. Burke Cancer Recovery Foundation International Mr. and Mrs. John Ric Brown CBRE Chronic Lymphocytic Leukemia Foundation Gale and Jean Burkett Cancer Research Institute Mr. and Mrs. Mike Brown Mr. and Mrs. Jeff L. Cecil Dr. and Mrs. William P. Chu Estate of Harry Burkhart III Mr. Ernest H. Cannon In Honor of Wayne Rita Ellis Brown Mr. Eugene Burleson Gibbens, Beth Gibbens, and Elizabeth Epley Cedar Street Charitable Foundation Mr. and Mrs. Russell P. Chubb Mr. and Mrs. Robin Brown Mr. Robert Burleson Mr. and Mrs. James J. Cano Celgene Corporation Mr. Tony Ciabattoni Mr. Steve T. Brown The Burleson Family Foundation Mr. and Mrs. Joe Ed Canon Estate of Joe Celli Mr. and Mrs. Michael M. Ciaccio Mr. Steven Brown Estate of Ena Burlingame Mr. Richard D. Cantalini Michael and Rebecca Cemo Foundation Brenda and Joseph Cialone, II Mr. Thomas A. Brown Mr. George K. Burnett Capital Farm Credit Central Louisiana Community Foundation Mr. and Mrs. Jim Cicconi Mr. Willard B. Brown Sue and Rusty Burnett Capitol Volkswagen Ms. Sandra L. Cepeda Ciera Bank Mr. William C. Brown Mrs. Susan E. Burns Mr. and Mrs. Jack Elias Capps Cepeda Systems & Software Analysis Ms. Barbara A. Ciesla Mr. and Mrs. William R. Brown Mr. Louis H. Buron, Jr. Mr. and Mrs. Raul Cardenas Mr. John Certa Circle D Land & Cattle Company, LLC T. J. Brown and C. A. Lupton Foundation, Inc. Mr. and Mrs. William A. Burrell Cardinal Health Foundation CFP Foundation Mr. and Mrs. Tim Cissell H. L. Brown, Jr. Family Foundation Mr. and Mrs. Harry W. Burrow Mr. Charles Carducci CGP Manufacturing, Inc. CITGO Petroleum Corporation Robert B. Brown Family Fund of the Toledo Sarah Lu Burrowes Mr. and Mrs. Bradley Cardwell Mr. and Mrs. D. B. H. Chaffe III Mr. and Mrs. Rob Citrone Community Foundation, Inc. Mr. Gerald G. Burtner Ms. Melissa B. Carery Mr. and Mrs. Gerald E. Chait D. Davidson Claiborne The Joe W. and Dorothy Dorsett Brown Mr. Charles Burton Mr. and Mrs. Rex W. Chamberlain The Clarence and Almeda Conrad Foundation The Andy Caress Melanoma Foundation Mrs. Billie Burwick Mr. and Mrs. Eugene C. Chambers Foundation Inc. The Brown Foundation, Inc. Mr. Charles P. Carey The Honorable and Mrs. George H. W. Bush Mr. and Mrs. Tommy Jack Chambers Mr. Jeffrey F. Clark Bradford and Yvonne Brown Gift Fund Dr. and Mrs. John S. Cargile Mr. Steven S. Bush Mr. William L. Chambers Mr. and Mrs. John P. Clark Mr. and Mrs. James R. Browning Mr. Blake M. Carlson Mr. and Mrs. William R. Bush The Carole and Gene Chambers Foundation Mrs. Kathryn Forrest Clark Mr. and Mrs. John Brozovich Mr. and Mrs. Joseph Carlson Ms. Anne H. Bushman Mr. and Mrs. Timothy J. Carlson Champion Realty, Ltd. Mr. Larry J. Clark The Samuel B. and Lorena J. Bruce Charitable Mrs. Ida M. Chan Meredith and Tom Clark Trust Dr. and Mrs. Rex D. Bushong, Jr. Mr. and Mrs. James E. Carlton III Estate of Cicely Chandler Mr. and Mrs. Paul N. Clark Mr. and Mrs. D. Forrest Brumbaugh Mr. and Mrs. John B. Butler Estate of Nancy D. Carmichael Mrs. Paula S. Butler Mr. and Mrs. Russ Chandler Mrs. Priscilla M. Clark and Mr. Robert J. Rebecca and Jon Brumley Mr. and Mrs. Brian J. Carmines Ensworth, Jr. Charles Butt Dr. Anne Chao and Mr. Albert Y. Chao Mr. Brent Brummett David M. Carmines Memorial Foundation, Inc. Mr. Ramsey E. Clark Mr. Herbert H. Butt Ms. Alicia G. Carner Mr. and Mrs. Brad Chapin

47 MD Anderson Annual Report

Mr. Richard Clark Coastal Transport Co., Inc. Mr. and Mrs. Archie L. Colburn Dr. and Mrs. Charles J. Colvin Concierge Services of Atlanta, Inc. The Honorable Ron and Joanna Clark Mr. and Mrs. Tim L. Cobb Mr. Shane Colburn Mrs. Michelle Comeau and Mr. William L. Concordia Foundation Mr. and Mrs. Charles F. Clarkson III Dr. and Mrs. Benton Cocanougher Mr. and Mrs. Carl W. Cole Schoen Mr. and Mrs. Robert Condon Mr. and Mrs. David A. Clay Mr. and Mrs. David A. Cockrell Estate of Marguerite Elizabeth Cole Comiskey Foundation C-One LLC Clays for Cara Mr. and Mrs. Ernest H. Cockrell Mr. and Mrs. Paul L. Cole Commonwealth Foundation for Cancer Conejos Group Corporation Mr. and Mrs. John D. Clayton Cockrell Family Fund Mr. and Mrs. Robert Cole Research The Honorable and Mrs. Peter R. Coneway Mr. and Mrs. Joseph A. Cleary, Jr. The Cockrell Foundation Mrs. Rose M. Cole Communities Foundation of Texas The Coneway Family Foundation Dr. and Mrs. John B. Clemmons Cockrell Interests LLC Sue and Jim Cole Communities of Coastal Georgia Foundation Mr. Lewis P. Conger The Cleveland Foundation Mr. and Mrs. Arthur B. Coen, Jr. Ben and Rose Cole Charitable PRIA Foundation Community Charity Advancement, Inc. dba Ms. Teresa Conger Breast Cancer Research & Support Fund Mr. and Mrs. Richard L. Clifford Mr. Bruce R. Cofer Mr. and Mrs. Chase Coleman III Mr. and Mrs. E. A. Conley The Community Foundation for Greater Mr. James R. Clifton Mary and Edward Coffey Mr. and Mrs. Peter Coleman Atlanta, Inc. Mr. and Mrs. John B. Connally III The Clifton Foundation Mr. Michael Coffey The Chase and Stephanie Coleman Foundation The Community Foundation for Northeast Mr. John B. Connally IV Mr. and Mrs. Gerald P. Clinch Mr. Perry Cohan Collaborative Ependymoma Research Network Florida Mr. and Mrs. Mark M. Connally Mr. and Mrs. James F. Clingman, Jr. Barton and Phyllis Cohen Mr. and Mrs. Charles F. Collard Community Foundation for Southeast Michigan Ms. Nell Frances Connally CLL Global Research Foundation Irwin and Gail Cohen Ms. Ruth Anne Colley The Community Foundation for the National Mr. Kevin J. Connealy Clorox Company Foundation Mr. and Mrs. James H. Cohen Drs. Wendy and Pat Collini Capital Region Mr. and Mrs. Jeffrey A. Connelly Mr. and Mrs. Omer Cloutier Mr. Melvin Cohen Ms. Carol J. Collins The Community Foundation of Abilene Mr. and Mrs. Jim Conner ClubCorp, Inc. Mr. and Mrs. Richard A. Cohen Mr. and Mrs. Philip N. Collins Community Foundation of Acadiana Mr. Robert Connolly Coach Sherrill’s Kickoff Team Scholarship Mr. and Mrs. Bernard L. Cohn Mr. and Mrs. T. Jay Collins Community Foundation of Greater Memphis Mr. and Mrs. Robert C. Connor Coastal Bend Community Foundation Mr. and Mrs. Bertram J. Cohn Mr. and Mrs. Ted Collins, Jr. The Community Foundation of Louisville, Inc. ConocoPhillips Coastal Deli Inc. Mr. Morton Allan Cohn Mr. William A. Collins III Community Foundation of North Texas Conquer Cancer Foundation of the American Coastal Spray Company Mr. and Mrs. Joseph Colaruotolo Colon Cancer Coalition Community Foundation of South Georgia, Inc. Society of Clinical Oncology Mr. Gregory N. Conrad Mr. and Mrs. Oliver A. Conrads Endowed Chairs Dr. and Mrs. Francis P. Conroy Dr. and Mrs. Scott Conroy PAUL AND MARY HAAS CHAIR IN GENETICS IN HONOR CHARLES AND DANEEN STIEFEL CHAIR IN CANCER HOWARD FOSTER SMITH AND LEE DENNIS SMITH CHAIR The Consulate General of the United Arab OF AMANDA MARIE WHITTLE RESEARCH IN HONOR OF MERRILL KIES, M.D., DAVID FOR CANCER RESEARCH IN THE FIELD OF HEMATOLOGY Emirates Michael Andreeff, M.D., Ph.D. ROSENTHAL, M.D., AND RANDAL WEBER, M.D. Elizabeth J. Shpall, M.D. Continental NH3 Products Ehab Y. Hanna, M.D. Convenience Marketing Services, Inc. COLIN POWELL CHAIR FOR CANCER RESEARCH FRANK T. MCGRAW MEMORIAL CHAIR IN CANCER Mr. Brian Cook Michelle Barton, Ph.D. BERNARD W. BIEDENHARN CHAIR IN CANCER RESEARCH RESEARCH Mr. and Mrs. Brian C. Cook John D. Hazle, Ph.D. Anil Sood, M.D. BEN F. LOVE CHAIR IN CANCER RESEARCH Mr. and Mrs. John R. Cook Richard R. Behringer, Ph.D. DAVID BRUTON, JR. CHAIR SUE AND RADCLIFFE KILLAM CHAIR Mr. and Mrs. Robert M. Cook John V. Heymach, M.D., Ph.D. Louise C. Strong, M.D. Mr. and Mrs. Si E. Cook FRANK T. MCGRAW MEMORIAL CHAIR IN THE Dr. and Mrs. Thomas Edwin Cook TREATMENT OF CANCER DALLAS/FORT WORTH LIVING LEGEND CHAIR FOR CHRISTOPHER AND SUSAN DAMICO CHAIR IN VIRAL Mr. and Mrs. Noel Coon Eduardo Bruera, M.D. CANCER RESEARCH ASSOCIATED MALIGNANCIES Mr. and Mrs. Clifton W. Coonrod Geoffrey S. Ibbott, Ph.D. Erich M. Sturgis, M.D. Ms. Cheryl A. Cooper CHARLES B. BARKER CHAIR IN SURGERY Mr. and Mrs. Glenn D. Cooper Charles E. Butler, M.D. DALLAS/FORT WORTH LIVING LEGEND CHAIR FOR MOSHE TALPAZ ENDOWED CHAIR IN IMMUNOLOGY Cooper Oil & Gas, Inc. CANCER RESEARCH II Shao-Cong Sun, Ph.D. ROBERT C. HICKEY CHAIR IN CLINICAL CARE Mr. and Mrs. Jerry E. Copeland V. Craig Jordan, Ph.D. Mrs. Lynn Copeland Richard E. Champlin, M.D. DALLAS/FORT WORTH LIVING LEGEND CHAIR FOR Corestates, Inc. JOHN G. AND MARIE STELLA KENEDY MEMORIAL CANCER RESEARCH III ANN RIFE COX CHAIR IN GYNECOLOGY Mr. and Mrs. Vic Corley FOUNDATION CHAIR David Tweardy, M.D. Robert L. Coleman, M.D. Loretta R. Cormier J. Jack Lee, Ph.D. M. G. AND LILLIE A. JOHNSON CHAIR FOR CANCER Dr. Yvonne C. Cormier and Mr. Rufus MARY BETH PAWELEK CHAIR IN NEUROSURGERY IN Cormier, Jr. IRVING AND NADINE MANSFIELD AND ROBERT DAVID TREATMENT AND RESEARCH HONOR OF DR. AND MRS. SAMUEL DICKENS BUGG AND Mr. and Mrs. Ron Corn LEVITT CANCER RESEARCH CHAIR Ara A. Vaporciyan, M.D. MR. AND MRS. ALBERT F. PAWELEK Mr. Allen Cornell Jeffrey E. Lee, M.D. Franco DeMonte, M.D. JOSE M. TRUJILLO CHAIR IN LABORATORY MEDICINE CorpTax, Inc. MATTIE ALLEN FAIR RESEARCH CHAIR Elizabeth A. Wagar, M.D. Carol and Thomas Corr J. RALPH MEADOWS CHAIR Guillermina Lozano, Ph.D. Mr. and Mrs. Charles A. Correll IN CARCINOGENESIS RESEARCH HUBERT L. STRINGER CHAIR IN CANCER RESEARCH Corrigan Family Holdings AT SCIENCE PARK-RESEARCH DIVISION NELLIE B. CONNALLY CHAIR IN BREAST CANCER John N. Weinstein, M.D., Ph.D. Corrigan Properties, Inc. Sharon Y. R. Dent, Ph.D. Funda Meric-Bernstam, M.D. Cos Bar at Woodlands, Inc. ANDERSON CLINICAL FACULTY CHAIR FOR CANCER Shirley and J. B. Coskey WILLIAM C. LIEDTKE, JR. CHAIR IN CANCER RESEARCH FRANK T. MCGRAW MEMORIAL CHAIR IN THE STUDY OF TREATMENT AND RESEARCH Mr. Steven Cosse Lee M. Ellis, M.D. CANCER Ignacio Wistuba, M.D. Mrs. Lisa C. Costello Bruce Minsky, M.D. REBECCA MEYER BROWN AND JOSEPH MELLINGER BETTY B. MARCUS CHAIR IN CANCER PREVENTION Cheryl Cotner BROWN CHAIR IN BASIC SCIENCE RESEARCH LARRY AND PAT MCNEIL CHAIR IN RADIATION Xifeng Wu, M.D., Ph.D. Mr. and Mrs. Charles H. Cotros Mr. and Mrs. Donald R. Cotten Varsha V. Gandhi, Ph.D. ONCOLOGY HONORING DR. JAMES D. COX Ms. Mariana P. Cotten Radhe Mohan, Ph.D. Mr. and Mrs. William T. Cottle DR. KENNETH B. MCCREDIE CHAIR IN CLINICAL As of Sept. 1, 2016 LEUKEMIA RESEARCH FERENC AND PHYLLIS GYORKEY CHAIR FOR RESEARCH Mr. and Mrs. James A. Cotton II Guillermo Garcia-Manero, M.D. AND EDUCATION IN PATHOLOGY Mr. David V. Couch Victor G. Prieto, M.D., Ph.D. Mr. William V. Couch Ms. Sylvia Y. Coulter

48 PARTNERS IN MAKING CANCER HISTORY

Ms. Shelia Countryman Mrs. Anna Tokareva Cukr Mr. and Mrs. Raymond G. Daugherty Del Sol Food Co., Inc./Briannas Distribuidora Domo, S.A. DE C.V. Mr. Leslie K. Courson Mr. and Mrs. Harry H. Cullen, Jr. Mr. and Mrs. Daniel Davenport Mr. and Mrs. Mark A. Delaney Di-Trol Systems, Inc. Mr. and Mrs. Mark A. Cover Mr. and Mrs. Harry H. Cullen, Sr. Mr. Raymond E. Davenport Mr. and Mrs. Edward J. Delatte, Jr. DKG Foundation Mr. and Mrs. Rox B. Covert The Cullen Trust For Health Care Mr. and Mrs. Robert M. Davenport Dr. Nancy J. Delboy DLJ Commercial Roofing, LLC Mr. and Mrs. James T. Covin Mr. Daniel E. Cullers David Yurman Enterprises LLC Mr. Michael L. Delcambre Dr. Ethan Dmitrovsky Mr. David Covington Mr. and Mrs. Dan R. Cullum Mr. and Mrs. Bruce G. Davidson Deli Management Inc. Mr. and Mrs. Robert J. Doan Mr. and Mrs. Jerry B. Cowan Mr. and Mrs. Tommy Culp Mr. and Mrs. Dennis R. Davidson Mr. William B. Deline Mr. and Mrs. Porter Dobbins Ms. Nancy Cowan Ivon and Jane Culver Charitable Trust Mr. and Mrs. Marc L. Davidson Dr. Alexander Dell Mr. and Mrs. James K. Dobbs III Mr. and Mrs. Philip Cowan Mr. and Mrs. Harry H. Cunningham Mr. and Mrs. Marty Davidson The Lorraine and Alexander Dell Foundation Ms. Kay C. Dobbs Mr. and Mrs. Holt Cowden Colonel and Mrs. Hamil M. Cupero, Sr. Mr. and Mrs. Philip A. Davidson Michael & Susan Dell Foundation Mr. Randall W. Dobbs Mr. Wright E. Cowden, Jr. Cure Fur Cancer Estate of Robert V. Davidson Dell Inc. Mr. Paul Dobson Mr. and Mrs. Michael C. Cowen The Cure Starts Now Foundation Mr. and Mrs. Simon D. Davidson Mr. Robert J. Dellafiora Mrs. Judy Dodson Mr. and Mrs. Joe Tom Cox Mr. Robert A. Curley, Jr. The M. N. Davidson Foundation Employees of DeLoitte & Touche Mr. and Mrs. Samuel R. Dodson III Mr. Thomas D. Cox Jim and Marion Currow Sheila Lee Davies Charitable Trust Mr. Benno J. Deltz Mr. and Mrs. Don J. Doerfler Chandler Cox Foundation Joan and Keys Curry Foundation Mr. Anthony M. Davila Mr. and Mrs. Willie G. Dement Ed and Susan Doherty Advised Fund Mr. and Mrs. Randy Coy Mr. Dennis P. Curtin Mr. Robert Davila Dement Contruction Company, LLC Mr. and Mrs. Steven Dola Mr. and Mrs. Richard Coy Mr. and Mrs. John Curtin Mr. and Mrs. Barry M. Davis Mr. John E. Dempsey Mr. and Mrs. Michael J. Dolan David and Nancy Coyle Mrs. Carolyn Ruth Curtis Ms. Blakely E. Davis Dr. Karin DeNevi Mrs. Beverly Dolinsky Mr. and Mrs. Thomas R. Craddick Mr. and Mrs. Robert C. Curtis Mr. and Mrs. Bruce G. Davis Mr. and Mrs. Early Denison Ms. Anna Dombrowski Mr. and Mrs. Larry J. Craddock Christy and Lou Cushman Carolyn and Platt Davis Denman/Newman Foundation Mr. and Mrs. Richard J. Domercq Mr. and Mrs. Vincent Dmitri Craig Ms. Teresa Cvitanovich Mr. and Mrs. Charles N. Davis, Jr. Ms. Margaret Dennett Mr. Michael W. Domino The Crain Foundation Cypress-Fairbanks ISD Mr. and Mrs. Don W. Davis Mr. and Mrs. Benjamin L. Denny Mr. David M. Donald Mr. Fred Cramm Cystic Fibrosis Foundation Estate of Ira Winfield Davis Hayden and Sandy Dent Oliver S. and Jennie R. Donaldson Charitable Trust Dr. and Mrs. William Crandall Mr. and Mrs. Dan Cytryn Mr. and Mrs. James E. Davis Mr. Leet E. Denton Mr. and Mrs. Ben A. Donnell Mr. Claude L. Crane Mr. and Mrs. Joe Bob Davis Ms. Gabrielle I. Dentraygues Mr. and Mrs. Michael S. Donoho Mr. and Mrs. Larry Crane Mr. and Mrs. Lee H. Davis Mr. and Mrs. R. Bruce DenUyl D Mr. and Mrs. Thomas J. Donohue Mr. Robert Cratchit Mr. and Mrs. Mark C. Davis The Denver Foundation The Donohue Family Foundation, Inc. Crave Cupcakes Houston, LLC Mrs. Patricia A. Davis Mr. and Mrs. Herb Depp D & H Cattle Company Don’s Specialty Meats II, Inc. Dr. Judith L. Craven and Dr. Moritz V. Craven Mrs. Peggy Davis Mrs. Charlotte J. Der Garry D & S Development LLC Sally and Rhew Dooley Mr. and Mrs. Thomas E. Cravens Mrs. Sheila G. Davis Mr. Joseph G. DeSantis D.E. Harvey Builders, Inc. Eddie E. Doré Cravens Warren & Company Davis Affiliates, LP Design Science Consulting, Inc. Mr. Richard M. Dadeks Mr. and Mrs. William J. Doré, Sr. Mrs. Joan W. Cravey Sam & Freda Davis Charitable Trust Detar Volunteer Services, Inc. Dadeks Machine Works Corp. Davis Chevrolet The Doré Family Foundation Mr. and Mrs. Daniel Crawford Dr. and Mrs. Dirk A. Dahlgren Mr. and Mrs. Jerry H. Deutser Mrs. Georgia M. Dorrough Mr. Donald B. Crawford The Charles and Melissa Davis Foundation Mr. and Mrs. David DeVido Mr. Raymond Dahlman Joe E. Davis Foundation Mr. and Mrs. Michael R. Dorsey Andrea and Bob Crawmer Ms. Eileen Devries Mr. and Mrs. William P. Dahlquist Davis Partners, LTD. Mr. and Mrs. Richard Parr Doss, Jr. Create Foundation, Inc. Gary and Cathy Dewey Mr. Forrest Daigle Mr. Danny Dawes Mr. Joe A. Dotterweich Creative Alloy Products Co. Inc. Mr. and Mrs. Gene Dewhurst Ms. Mary Dailey Dawes Contruction LLC Doug Boyd Motor Co. Creator’s Canvas Cancer Research Foundation Mrs. Patricia Hamilton Dewhurst Mr. Michael W. Dale Mr. L. Decker Dawson Mrs. Melinda Douglas Mr. and Mrs. Percy P. Creuzot III Dewitt and Associates LLC Mr. Mitchell M. Dale David Q. and Lois Day Mr. Russell Douglas Mr. and Mrs. Jerry M. Crews Mrs. Diana L. Di Pietro Mr. Robert Dale Mr. James C. Day The Dow Chemical Company Foundation Mr. John E. Crisp DialAmerica, Inc. Mr. Joseph Daley Mr. and Mrs. Robert S. Dayton Mr. and Mrs. Dan M. Dowdey Mr. and Mrs. Douglas E. Crockard Mr. and Mrs. George Diamantis Mr. Bob Dallas Dayton Foundation Depository, Inc. Mr. and Mrs. Greg Dowell Mr. and Mrs. James H. Crocker Ms. Allyson Dias Dallas Fort Worth Metropolitan Dayton Independent School District Downman Family Foundation Miss Krista Crockett Allyson K. Dias Foundation Dallas Jewish Community Foundation Dayton-Phoenix Group, Inc. Mr. Eric J. Doyal Harry Crockett Trust Dr. and Mrs. Eduardo M. Diaz, Jr. Mr. and Mrs. Louis J. D’Ambrosio Mr. Richard J. De Blieck Mr. and Mrs. Robert J. Doyle Crohn’s and Colitis Foundation of America Mr. and Mrs. Christopher Dickens Mrs. Shilpa C. Damle-Mogri Mr. Rafael De La Vega Mr. and Mrs. Robert W. Doyle Mr. and Mrs. Christopher J. Crosby, Sr. Donald P. Dampf Mr. and Mrs. David M. de Leon Mr. Ronald J. Dickens Jeff and Ann Drabing Mr. and Mrs. Steve Crosby Estate of Mary Victoria Damsgaard Mr. and Mrs. John A. Deakins Mr. and Mrs. John R. Dickerson Ms. Diann D. Drake Mr. John W. Cross Mr. Richard Dangelmayr Mr. Samer Danial Deal Sikes & Associates Mr. and Mrs. Peter H. Dickerson Mr. and Mrs. Harold M. Draughon RNR Cross Family Foundation Mr. Bill Daniel Ms. Alisa Dean Mr. and Mrs. William H. Dickert, Jr. Ms. Truedy M. Dreier Mr. William B. Crouch, Jr. Mr. and Mrs. Thomas J. Daniel Estate of Clemence Alice Deane Dr. Burton F. Dickey Mr. Walter W. Driver, Jr. Mr. and Mrs. Guinn D. Crousen Daniel B. Hastings, Inc. Mr. Henry DeAngelis, Jr. Mr. Ernest J. Dickinson Alfonso and Mary Young Duarte The Robert Page Crozer Family The Leo Daniel Foundation Dr. James R. Dear Mr. and Mrs. Marcus D. Dickson Mr. Melvin Dube Mr. and Mrs. Thomas H. Cruikshank, Sr. Mr. Earl N. Daniels Mr. and Mrs. Alfred L. Deaton III Mr. Terry Dickson Oscar and Loretta Dube John and Vicki Crum Marjorie M. and William R. Daniels Ms. Judith DeBoard Didak, Inc. Ms. Judy Walker Duck Sylvie and Gary Crum Mr. and Mrs. James D. Dannenbaum Estate of Hall J. DeBusk Mr. and Mrs. Peter U. Diebold Mrs. Karen Arthur Duddlesten Mr. and Mrs. E. Lea Crump Danny’s Asphalt Paving, Inc. DeCesaris/Prout Cancer Foundation Martin W. Dies III Wayne Duddlesten Foundation Mr. and Mrs. Richard K. Crump Danny’s Dining, Inc. Mrs. Elizabeth A. Decker Mr. and Mrs. Hadden M. Dietrich Ms. Jane C. Dudek Mrs. Lin G. Cruse Darden Family Charitable Foundation Mr. and Mrs. Michael W. Deeds Mr. and Mrs. Timothy W. Dietrich Mr. and Mrs. Robert L. Dudzik Mr. and Mrs. Joe Crutcher Ms. Anna Hilary Darilek Deerfield Episcopal Retirement Mr. and Mrs. Richard E. Dietrichson, Jr. Mr. James E. Duffy III Mr. and Mrs. Edward E. Crutchfield Ms. Dianne L. Darlin Community, Inc. Mr. and Mrs. Alfred G. Diggles Mr. and Mrs. Michael Duffy Crutchfield Family Foundation Mr. Daniel G. Darling Mr. Brad G. Defenbaugh Dr. Nancy Hiatt Dilley and Dr. Jim Dilley Dr. and Mrs. Jack Dugan Mr. and Mrs. Nicholas Csendes Mr. and Mrs. Dennis J. Darling Mr. Bill Deffebach Mr. Perry A. Dillon, Jr. Dugan Family Foundation Dr. and Mrs. Matthew P. Cubbage Mr. and Mrs. Thomas P. Darmstadter Mr. and Mrs. Homer H. DeFord Mr. and Mrs. Nicholas DiMeglio Mrs. Marta H. Duhon Mr. and Mrs. John S. Cubbon Mr. Charles G. Darnell, Jr. Mrs. Linnet F. Deily The Dinerstein Companies Mr. Albert Dukart Cubbon Lumber and Land Co. Dart Container Rafael del Barrio Mr. and Mrs. Michael J. Dipp Dulles High School - FBISD Mr. Kevin James Cuene Mrs. Martha C. Daugherty Del Papa Distributing Co., Inc. Shanon and Lori DiSorbo Mr. and Mrs. Charles E. Dunagan 49 MD Anderson Annual Report

Endowed Distinguished Professorships Mrs. Gail L. Dupre Mr. James B. Ellis II and Ms. Margaret R. Mr. and Mrs. Rob Dupree Brady BIRDIE J. AND LYDIA J. RESOFT DISTINGUISHED PROFESSORSHIP DEL AND DENNIS MCCARTHY DISTINGUISHED PROFESSORSHIP Dr. and Mrs. Leonel D. Durbin Mr. Ernest Ellison II IN GASTROINTESTINAL ONCOLOGY IN GASTROINTESTINAL CANCER RESEARCH Mr. Robert R. Durden The Ellison Medical Foundation Robert Bresalier, M.D. Jeffrey Morris, Ph.D. Ms. Denise D. Durel Mr. John E. Ellisor Mr. Richard S. Durham Mr. Kyle Ellisor EDWARD ROTAN DISTINGUISHED PROFESSORSHIP HUBERT L. AND OLIVE STRINGER DISTINGUISHED Mr. and Mrs. Kenneth W. Dusek The Ellwood Foundation Aman Buzdar, M.D. PROFESSORSHIP IN CANCER RESEARCH Ms. Dede Duson Mr. Ahmed El-Mahdawy Jeffrey N. Myers, M.D., Ph.D. Mr. and Mrs. Gerry M. Elphingstone, Jr. ANNIE LAURIE HOWARD RESEARCH DISTINGUISHED Dwight Andrus Insurance Mr. Kevin W. Dwyer Barry R. and Karen B. Elson and Family PROFESSORSHIP N. G. AND HELEN T. HAWKINS DISTINGUISHED PROFESSORSHIP Mrs. Lois W. Dyk Mr. Matthew B. Ely Paul M. Cinciripini, Ph.D. FOR CANCER RESEARCH Mr. and Mrs. Gregory B. Dykes Mr. and Mrs. Mads Emanuelsen Hui-Lin Pan, M.D., Ph.D. RICHARD E. HAYNES DISTINGUISHED PROFESSORSHIP Mr. and Mrs. John Dzubinski Walter and Gayle Embrey FOR CLINICAL CANCER PREVENTION JAY AND LORI EISENBERG DISTINGUISHED PROFESSORSHIP Dr. and Mrs. Michael W. Emerson Emerson Process Management Valve Lorenzo Cohen, Ph.D. Vali Papadimitrakopoulou, M.D. E Automation GLORIA LUPTON TENNISON DISTINGUISHED PROFESSORSHIP ROBERT R. HERRING DISTINGUISHED PROFESSORSHIP Mr. Leonard E. Emge E. A. Sween Company Emily’s Power for a Cure Foundation IN LUNG CANCER RESEARCH IN CLINICAL RESEARCH Mr. and Mrs. Rodney W. Eads Ritsuko Komaki Cox, M.D. Shreyaskumar R. Patel, M.D. Mr. John Emmitte Mr. and Mrs. Jerry T. Eason EnCana Cares (USA) Foundation CLIFTON D. HOWE DISTINGUISHED PROFESSORSHIP KATHERINE RUSSELL DIXIE DISTINGUISHED PROFESSORSHIP East Tennessee Foundation’s Richard H. Encore 3.0 CD - Southcoasters Roberts Fund IN PULMONARY MEDICINE IN PEDIATRICS Energy Transfer Partners LP East Texas Communities Foundation Burton F. Dickey, M.D. Alexander V. Prokhorov, M.D., Ph.D. EnergyQuest II, LLC Mr. and Mrs. Lyle A. Eastham Mr. George B. Eng TEXAS 4000 DISTINGUISHED PROFESSORSHIP GERALD P. BODEY, SR. DISTINGUISHED PROFESSORSHIP Mr. and Mrs. S. Stacy Eastland Engineered Air Balance Co., Inc. Kim-Anh Do, Ph.D. IN INFECTIOUS DISEASE Dr. and Mrs. Charles Eaton Mr. and Mrs. John M. Engler Issam Raad, M.D. Ms. Wanda J. Eaton Mrs. Shirley B. Engler SOPHIE C. STEVES DISTINGUISHED PROFESSORSHIP Mr. and Mrs. Raymond H. Eaves Mr. and Mrs. Michael T. English IN CANCER RESEARCH DR. JOHN R. STROEHLEIN DISTINGUISHED PROFESSORSHIP Ms. Nancy Ebe and Mr. Steven H. Meyer Ms. Ann Enloe Cathy Eng, M.D. IN GASTROENTEROLOGY Ms. Elise Renee Eberwein ENT of Georgia, LLC G. S. Raju, M.D. Mr. E. Llwyd Ecclestone, Jr. HELEN SHAFER FLY DISTINGUISHED PROFESSORSHIP OF Employees of Entergy Mrs. Christy G. Echols EOG Resources, Inc. ANESTHESIOLOGY, IN HONOR OF BERTHA DAVIS-CLARK, M.D. CHARLES M. MCBRIDE DISTINGUISHED PROFESSORSHIP Dr. and Mrs. David J. Eckberg Thomas W. Feeley, M.D. IN SURGICAL ONCOLOGY EPIC Mr. and Mrs. Jack P. Eckels Elizabeth and Mark Epley Merrick I. Ross, M.D. ABELL-HANGER FOUNDATION DISTINGUISHED PROFESSORSHIP Estate of Mae Eckstein Mr. Richard B. Eppler Mr. and Mrs. Raymond A. Eckstein, Jr. Bonnie S. Glisson, M.D. EDGAR LEWIS CURTIS, SAVILLA ELIZABETH CURTIS AND Epsilon Raymond A. Eckstein, Jr. and Roslyn S. Susan and Bobby Epstein ELEANOR LEWIS CURTIS DISTINGUISHED PROFESSORSHIP Eckstein Foundation THE HAMILL FOUNDATION DISTINGUISHED PROFESSORSHIP Mr. and Mrs. Wayne Epstein IN PEDIATRIC CANCER RESEARCH Eddy Packing Company, Inc. IN HONOR OF DR. RICHARD G. MARTIN, SR. Equifax, Inc. Cindy L. Schwartz, M.D. Mr. and Mrs. Robert L. Edenbaum Kelly K. Hunt, M.D. Equine Medical Associates, PA Mr. David Edge NAGUIB A. SAMAAN DISTINGUISHED PROFESSORSHIP Erdheim-Chester Disease Global Alliance P. H. AND FAY E. ROBINSON DISTINGUISHED PROFESSORSHIP IN Estate of Erna A. Edmunds Mr. and Mrs. Earl P. Erdmann IN ENDOCRINOLOGY Mr. and Mrs. Jack B. Edrington CANCER RESEARCH Mrs. Cynthia Erickson Steven I. Sherman, M.D. Mr. and Mrs. David Edwards Henry Mark Kuerer, M.D., Ph.D. Mr. and Mrs. Sheldon R. Erikson Mr. and Mrs. James R. Edwards BARNTS FAMILY DISTINGUISHED PROFESSORSHIP Dr. and Mrs. Fred Erisman III RUBY E. RUTHERFORD DISTINGUISHED PROFESSORSHIP Mr. Jeffrey Stuart Edwards IN CANCER RESEARCH Ernest H. Cannon & Associates Zhimin Lu, M.D., Ph.D. Mr. Patrick M. Edwards Maria E. Suarez-Almazor, M.D., Ph.D. Ernst & Young, LLP Ms. Ruth A. Edwards JAMES E. ANDERSON DISTINGUISHED PROFESSORSHIP Mr. and Mrs. John Erskine NYLENE ECKLES DISTINGUISHED PROFESSORSHIP Mr. and Mrs. Wes Edwards Mr. and Mrs. John W. Erwin IN NUCLEAR MEDICINE Joseph Eglin IN BREAST CANCER RESEARCH The Honorable and Mrs. Mark W. Erwin Homer A. Macapinlac, M.D. Mr. Lynn R. Eidson Naoto T. Ueno, M.D., Ph.D. Mr. Raul T. Espino Myra Eilenberg Trust MONTELEONE FAMILY FOUNDATION DISTINGUISHED Mr. and Mrs. Wilmot J. Estes GRADY F. SAUNDERS, PH.D. DISTINGUISHED PROFESSORSHIP Mr. and Mrs. Donald Joseph Einecker PROFESSORSHIP FOR RESEARCH OF BLADDER AND Mr. John Estey FOR MOLECULAR BIOLOGY Mr. and Mrs. Pete Eischen KIDNEY CANCERS Mr. and Mrs. Billy G. Euell, Jr. Richard D. Wood, Ph.D. Mr. and Mrs. Charles W. Eisemann Surena Matin, M.D. Mrs. Ann A. Eutsler Mr. and Mrs. Stefan Eisen, Jr. Mr. and Mrs. Arthur Russell Evans Mr. and Mrs. Jay S. Eisenberg VIRGINIA H. COCKRELL DISTINGUISHED PROFESSORSHIP As of Sept. 1, 2016 Pame and Roy Gene Evans Ms. Joyce H. Eiszner IN IMMUNOLOGY Susie and Don Evans Eiszner Family Foundation Jeffrey Molldrem, M.D. Dr. Tracy Bialy Evans Elaine Turner Designs, LLC Mr. and Mrs. Russell L. Everatt Mr. and Mrs. Phillip O. Elbert Mr. and Mrs. James H. Everest Mr. Carel Vernon Dunaway Mr. and Mrs. John H. Duncan, Jr. Linda and Archie Dunham Elgin Breeding Service, Inc. Mr. and Mrs. Carl B. Everett III Kathy Raby Dunaway Mr. and Mrs. John H. Duncan, Sr. Mr. and Mrs. Robert A. Dunkel Mr. and Mrs. John W. Elias Mr. Eric Everett Mr. Donald G. Dunbar, Jr. Robert Duncan The Honorable and Mrs. Caswell J. Dunlap The Howard and Susan Elias Foundation Exxon Mobil Corporation Bob and Patty Duncan and Family Mr. Robert L. Duncan Mr. Gary Dunlap Susan M. Ellerbeck and Ronald L. Ellerbeck Linda and Simon Eyles Foundation Mr. and Mrs. Charles W. Duncan, Jr. Mr. and Mrs. William G. Duncan Mr. and Mrs. Andrew Dunn Ellerbeck Family Foundation Mrs. Elles V. Eysbroek Mrs. Dan L. Duncan Dan L Duncan Family Mr. and Mrs. John S. Dunn, Jr. Mr. John Ellior Mr. Donald R. Duncan The Duncan Genesis Foundation John S. Dunn Foundation Mr. and Mrs. James E. Elliott

50 PARTNERS IN MAKING CANCER HISTORY

F Fidelity Investments Fondation AVEC Mr. and Mrs. Stanley K. Friedman Mrs. Wanda M. Garner Mr. and Mrs. A. Gary Fieger The Fondren Foundation Dr. and Mrs. Evan T. Friend Mr. and Mrs. Gardiner W. Garrard, Jr. Mr. and Mrs. Mauricio Fabre Mr. and Mrs. Jerry D. Fields Mr. Eric Fontenot Dr. Kathleen Daniel Friesenhahn and Mr. James and Janet Garrett Dr. and Mrs. John E. Fagan Dr. Tina T. Fields Mr. and Mrs. Bill Foote Vernon C. Friesenhahn Mr. and Mrs. James H. Garrison, Jr. Mr. and Mrs. Robert Fagenson Mr. Daniel Fierro Dr. Susan Foote and Mr. Stephen L. Feinberg Mr. Parker Frisbie Pamela and Wayne Garrison Mr. and Mrs. Neil N. Fahmy Fifth Generation, Inc. Mr. John C. Forbes Mr. Mike Frisk Mr. Robert W. Garthwait, Sr. Mr. Steven J. Fair Brendan and Louisa Fikes Mr. and Mrs. Daniel P. Ford Mr. Gregory T. Fritsch Mr. and Mrs. Mike Garver Mr. Richard Fairbanks Mr. and Mrs. Jude B. Filippone Mrs. Judith A. Ford Ms. Candice Fritschner The Garver Foundation Mr. and Mrs. Richard W. Fairchild, Jr. Mr. and Mrs. Matthew J. Filpovich Mr. and Mrs. Victor F. Fore Mr. Michael H. Fritz Mr. and Mrs. Charles F. Garvey FAITH “Fighting Cancer” In Montgomery Mrs. Mildred F. Finch Mr. Thomas Forestier Mrs. Dorothy C. Fritze Mr. and Mrs. Anthony F. Garvin County Mr. & Mrs. D. Bruce Fincher Mr. and Mrs. Leonard Forey Mr. David R. Frohn Mr. Abraham Garza III Ms. Patrice Falagrady and Mr. William Young Mrs. Nanette B. Finger Mr. Elbert Forman Mr. and Mrs. Robert C. Froman Sharon Lee Gaskill Ms. Christine M. Falgout and Mr. William Jerry and Nanette Finger Foundation Ms. Tracy J. Forrest Frontier Bank of Texas, Elgin & Bastrop Mr. Kenneth L. Gaspar Gutknecht Sandy Chait Finiasz Cancer Foundation, Inc. Mrs. Anne A. Forrester Frontier Communications Ms. Jill Gaston Jo Lynn and Gregg Falgout Estate of John K. Finlayson Mr. and Mrs. Brad Forrester Frontier Science & Technology Research Gastroesophageal Cancer Foundation Inc. Ms. Kimberly A. Falgout George and Phyllis Finley Mrs. Sylvia L. Forsyth Foundation, Inc. Mr. and Mrs. Thomas A. Gates Patty and Larry Fallek Mr. and Mrs. Jody J. Finley Mr. and Mrs. John J. Foster Mr. and Mrs. David B. Frost Gateway for Cancer Research Diane Lokey Farb in honor of Harold Farb Mr. and Mrs. John W. Finney, Jr. Foster Poultry Farms Frost Bank Mr. and Mrs. Mike Gatewood Ms. Claudia E. Farinola and Mr. Brad Dorsey First Christian Church Foundation for Anesthesia Education and The Fruehauf Foundation Ms. Susan Gatton Mr. and Mrs. Bernard Farkas First Clearing, LLC Research Mrs. Adrienne Frumovitz Mr. and Mrs. John O. Gaudin Mr. Carrie Farmer First Financial Bank Foundation for the Carolinas Mr. and Mrs. Jay N. Fry Dr. Dianna Gaultney Mrs. Jennie Snyder Farmer First National Bank Albany/Breckenridge The Foundation for the National Institutes of Mrs. Eleanor M. Frye Dorothy L. Gaultney Health Mr. and Mrs. Richard T. Farmer First National Bank of Bastrop, Elgin, Smithville Mr. and Mrs. Barton L. Fuchs Mr. and Mrs. Luther P. Gause The Farmer Family Foundation FirstSouthwest Company Foundation for Women’s Cancer Mr. and Mrs. Isidro Fuentes Four Seasons Landscaping, Inc. Mr. and Mrs. Kelly Gauthreaux Mr. and Mrs. Bobby R. Farris Mr. and Mrs. William T. Firth Full of Grace 5K Mr. and Mrs. Edgar L. T. Gay Mr. and Mrs. G. Steven Farris Estate of Helen H. Fourmy Mr. Thomas V. Fischer Mr. and Mrs. George L. Fuller, Jr. Mr. William M. Gayhart Mr. and Mrs. Spencer Fast Mr. Greg Fourticq, Jr. Mrs. Courtney Fischer-Brown and Mr. Jason Mrs. Sandra T. Fuller Mrs. Martha Gayle Mrs. Jane Elizabeth Fatino Brown Mr. and Mrs. Michael J. Fourticq William M. Fuller Foundation Mrs. Louise Gaylord Mr. and Mrs. Gerald L. Faulconer Anders and Ossa Fisher Mrs. Patsy Fourticq Anna Fuller Fund E. L. and Thelma Gaylord Foundation Ms. Betty J. Faulkner Mr. and Mrs. Andersen C. Fisher Mr. and Mrs. Randy A. Foutch Mrs. Monica E. Fulton GBC Benefits, LTD. Dr. Renee Favret Mr. and Mrs. Bryan Fisher Ms. Janet Fowler Dr. and Mrs. James M. Funk Mr. Michael R. Fowler Ms. Cynthia Gdula and Mr. L. Charles Ms. Romelia Favrot and Mr. M. Harris Mr. Chuck Fisher Mr. and Mrs. J. Rex Fuqua Westervelt Greenwood Mr. and Mrs. Gregory J. Fisher Mr. and Mrs. Michael R. Fowler FutureUS Foundation GE Foundation Carolyn Grant Fay Mr. Joseph J. Fisher, Jr. Dr. Sandra C. Fowler and Mr. Earl L. Fowler Jr. GE United Way Campaign Mr. and Mrs. Robert L. Feavel Bella and Ilya Fishman Mrs. Christina Fox Mr. and Mrs. James F. Geary Mr. and Mrs. Lonnie M. Fedrick Mrs. Dorothy S. Fitch Mr. G. Douglas Fox G Mr. and Mrs. Robert T. Gebert Dr. Kelli Cohen Fein and Mr. Martin J. Fein Kathy and Kerry Fitzgerald Mr. and Mrs. Steve L. Fox Mr. and Mrs. Gregory R. Geib Mr. and Mrs. Andrew M. Feinberg Dr. and Mrs. Mel Flamenbaum Mr. Wayne C. Fox Mr. and Mrs. Louis S. Gaeke, Jr. Mr. and Mrs. Thomas R. Geisenheimer Randi Feinberg Mr. and Mrs. Jimmy Flanagan Woody Fox Ms. Deena L. Greer and Mr. Carl Gagliardi Mr. and Mrs. William R. Geiser Feinberg Foundation Ms. Cindy Fleischer The Terry Fox Foundation Mrs. Carol J. Gagnon The Honorable Bruce S. Gelb Betty Feinberg, Randi Feinberg, Lori Feinberg David and Judy Fleischer Mr. and Mrs. Michael S. Francisco Mrs. Anna L. Gahm Mr. and Mrs. Glen J. Gelormini Kany, Peter E. Feinberg, and Jami Simons Mr. and Mrs. Richard Fleischman The Rhoda & Henry Frank Family Foundation II Mr. and Mrs. Jim L. Gaines Dr. Donald C. Gentry Mrs. Bernice R. Feld Ms. Catherine P. Fleischner Estate of Ruth “Ella” Lara Franklin Mr. and Mrs. Orville D. Gaither Mr. and Mrs. James Gentry Mr. and Mrs. James Feldick Mr. and Mrs. Justin Flick E. A. Franklin Charitable Trust, Mary McCrary, The Gaither Foundation Mrs. Margaret Anderson Gentry Dr. Gayla B. Feldman and Mr. Steven W. Mr. and Mrs. James A. Flieller Trustee Dr. Carol A. Galeener Feldman Mr. Bruce Flint Mr. and Mrs. Rick D. Fransen Melvyn P. and Eleanor N. Galin Family Genzyme Corporation Mrs. Ouida W. Felker Flint Hills Resources Mr. Merlon Frantom Foundation Mr. Freddie C. George Mr. Sam Fellows Ms. Mary A. Flood Mr. and Mrs. Fred Frantz Mr. and Mrs. David K. Gallagher Mr. and Mrs. R. James George, Jr. Mr. and Mrs. Jones A. Felvey II Ms. Jan Florence Mr. Charles Fraser Mr. and Mrs. Gordon L. Gallagher Georgia Power Foundation, Inc. Mr. Michael Felvey Cherie and Jim Flores Mr. Loyd R. Fraser Parents of Kevin M. Gallagher Ms. Judy Geraci Feng Shui Inc. Florida Irrigation Supply, Inc. Mr. Mark Frazer Mrs. Patricia M. Gallagher Mrs. Angie Gerber Mr. Wade G. Fennel Mrs. Juliet Flory Mr. and Mrs. Gregory R. Frazier Lt. Colonel Thomas W. Gallagher, Jr. Mr. Denny Gerdeman Mrs. Joan K. Fenner Dr. John W. Flory Foundation Mrs. Jean W. Frazier Mr. and Mrs. James L. Gallogly Mr. Jack L. Gerdes Ms. Nhu T. Fenske Mrs. Patricia L. Flower Mr. and Mrs. Michael E. Frazier Gallogly Family Foundation Mrs. Janelle Gerhardt Mr. Allen Ferguson Sharon and Bobby Floyd Ms. Sandra A. Frazier Dorothy and Ray Galvin Ms. Kleta J. Gerhart Mrs. Betty M. Ferguson Mrs. Gracia E. Floyd Fred Hutchinson Cancer Research Center Mrs. Janet C. Gambell Mr. and Mrs. Rod Gesten Mr. and Mrs. Earl M. Ferguson Mr. Jay H. Floyd, Jr. Mr. and Mrs. Norman D. Frede Mr. and Mrs. Gary B. Gamble Mrs. Vera Getz Mr. and Mrs. John W. Ferguson Jim and Gracia Floyd and Mr. and Mrs. William Marguarette and George Frederick Mr. and Mrs. James J. Ganger GFWC Woman’s Wednesday Club of Granbury Mr. Lazaro H. Fernandez B. Batt Mr. and Mrs. Robert J. Fredrikson Jenkins Gann Foundation Mr. Suhail J. Ghandour Mr. Melvin J. Ferreira Mr. and Mrs. Peter J. Fluor Twilight and Marc Freedman Foundation Mr. Edward J. Gannon The Giardina Family Foundation Mr. and Mrs. Frank J. Fertitta III Fluor Corporation Mr. and Mrs. Bill D. Freeman Ann and Larry Garberding Beth and Wayne Gibbens Mr. and Mrs. Jason L. Fertitta The Fluor Foundation Mr. and Mrs. Jerry W. Freeman, Jr. Mr. Carlos Acosta Garcia Mr. Edward E. Gibbs Ms. Kelley-Ann Fertitta Mr. Troy Fogarty Ms. Julie Ann Freeman Mr. and Mrs. Joe E. Garcia Mr. and Mrs. James R. Gibbs Mr. Joseph Fidanque, Jr. Ms. Carolyn E. Fogg Mr. and Mrs. Kenny Freeman Mr. Saul Garcia Mr. John D. Gibbs Mr. Joseph Fidanque III Mr. and Mrs. Donald G. Fogg, Jr. Freeport-McMoRan Foundation Mr. and Mrs. David S. Gardner Mr. and Ms. Michael E. Gibbs Ms. Myra Fidanque Mr. and Mrs. Kenneth G. Follansbee, Sr. Mrs. Marcia Fuller French Lily and Ronald Garfield Mr. Walter P. Gibbs, Jr. Fidanque Foundation Mr. and Mrs. John Follis Mr. Harold Friedman Mr. and Mrs. John C. Gargani Mr. Fred D. Gibson, Jr. Fidelity Brokerage Services LLC Dr. and Mrs. David S. Followill Mr. Richard S. Friedman Mr. Donald Garland Mr. and Mrs. Gary F. Gibson

51 MD Anderson Annual Report

Endowed Professorships Godfather’s Pizza Ms. Mary Ann Graf Mr. Gary Godwin Mr. Larry O. Graff Dr. and Mrs. Helmuth Goepfert Mr. Creig Graham DOCTOR R. LEE CLARK PROFESSORSHIP FELIX L. HAAS PROFESSORSHIP IN BASIC SCIENCE Mrs. Joyce L. Goerke Mrs. Donna A. Graham Christian R. Abee, D.V.M. Macus Tien Kuo, Ph.D. Mr. and Mrs. Glenn Goertz Mr. and Mrs. Robert H. Graham HELEN BUCHANAN AND STANLEY JOSEPH SEEGER RESEARCH ELZA A. AND INA S. FREEMAN ENDOWED PROFESSORSHIP IN Mrs. Frances A. Goetz Dr. and Mrs. William L. Graham PROFESSORSHIP LUNG CANCER Mr. and Mrs. Charles F. Goff Phil and Wendy Gramm Salahadin Abdi, M.D., Ph.D. Jonathan M. Kurie, M.D. Mr. and Mrs. John C. Goff Claire and Jeff Granberry Mr. and Mrs. Walter S. Going III Mr. and Mrs. William R. Granberry RANSOM HORNE, JR. PROFESSORSHIP FOR CANCER RESEARCH DR. JOHN MURRAY PROFESSORSHIP IN ORTHOPAEDIC Mrs. Carol S. Gold Grand Prix Charities of Houston Keith Baggerly, Ph.D. ONCOLOGY Ms. Kim Gold Grand Trunk Western Railroad Company Valerae O. Lewis, M.D. Mr. and Mrs. Lawrence J. Gold Merle and William Granek THE KENNETH D. MULLER PROFESSORSHIP IN TUMOR GENETICS Lance Goldberg Mrs. Betty L. Grant Mark Bedford, Ph.D. HUBERT L. AND OLIVE STRINGER PROFESSORSHIP FOR Mr. Neil A. Goldberg Mary A. & Thomas F. Grasselli Endowment CANCER TREATMENT AND RESEARCH ASHBEL SMITH PROFESSORSHIP Mr. and Mrs. Robert L. Goldberg Foundation Lei Li, Ph.D. Mr. and Mrs. Andrew E. Graves Diane Bodurka, M.D. Mr. Barry Golden Mrs. Eloise L. Golden Mr. and Mrs. Robert R. Graves UNITED ENERGY RESOURCES, INC. PROFESSORSHIP ASHBEL SMITH PROFESSORSHIP Linda and Ray Golden Mr. and Mrs. Horace A. Gray Xin Lin, Ph.D. Paul J. Chiao, Ph.D. Barbara Segal Goldfield Dr. and Mrs. Kenneth N. Gray JOHN Q. GAINES FOUNDATION PROFESSORSHIP FOR Golding Barge Line, Inc. Mr. Richard W. Gray III MCCULLOUGH PROFESSORSHIP FOR CANCER RESEARCH CANCER RESEARCH Goldman, Sachs & Co. The Greater Cincinnati Foundation Charles S. Cleeland, Ph.D. Gabriel Lopez-Berestein, M.D. Goldman Sachs Philanthropy Fund Greater Horizons H-E-B PROFESSORSHIP IN CANCER RESEARCH Mr. and Mrs. Frank A. Goldsmith Greater Houston Community Foundation FLORENCE MAUDE THOMAS CANCER RESEARCH The Greater Kansas City Community Patrick M. Dougherty, Ph.D. Golfers Against Cancer, Inc. PROFESSORSHIP Mr. and Mrs. Julio C. Gomez Foundation BLANCHE BENDER PROFESSORSHIP IN CANCER RESEARCH Robert Z. Orlowski, M.D., Ph.D. Julio and Ana Gomez Foundation The Greater Miami Jewish Federation Madeleine Duvic, M.D. Mr. Jorge Gonzales, Jr. Mr. and Mrs. William E. Greehey RUTH AND WALTER STERLING PROFESSORSHIP Mr. and Mrs. Kevin G. Gonzales Greehey Family Foundation KENNETH D. MULLER PROFESSORSHIP IN MELANOMA Nancy D. Perrier, M.D. Mr. and Mrs. Adrian G. Gonzalez Mr. and Mrs. Charles Edward Green RESEARCH Ms. Haley Green JANIECE AND STEPHEN A. LASHER PROFESSORSHIP Ms. Jeanie C. Gonzalez Adel K. El-Naggar, M.D., Ph.D. Ms. Mayra Gonzalez Mr. Joe R. Green Farhad Ravandi-Kashani, M.D. Mr. Mark Green KATHRYN O’CONNOR RESEARCH PROFESSORSHIP Ms. Sylvia Gonzalez A CONVERSATION WITH A LIVING LEGEND PROFESSORSHIP Mr. and Mrs. Norman N. Green Ziding Feng, Ph.D. Mrs. Nancy C. Good Yu Shen, Ph.D. Good Friday Golf Tournament Sherrie and Robert Green DR. JOHN M. SKIBBER PROFESSORSHIP FOR Ms. Anne L. Goodman Mr. and Mrs. William H. Green, III ANISE J. SORRELL PROFESSORSHIP SURGICAL ONCOLOGY Scott K. Goodman Mr. Dean Greenberg Peter F. Thall, Ph.D. Jeffrey Gershenwald, M.D. Mr. and Mrs. Jimmy Goodson Mr. and Mrs. Raymond Greenberg Mr. Theodore S. Greenberg MATTIE ALLEN FAIR PROFESSORSHIP IN CANCER RESEARCH Mr. and Mrs. Kenneth E. Goodson ASHBEL SMITH PROFESSORSHIP Mr. and Mrs. Irving I. Greenblum Elizabeth L. Travis, Ph.D. Mr. and Mrs. Peter Goodwin Peng Huang, M.D., Ph.D. Philip and Kay Goodwin Mr. and Mrs. Jim Greene DALLAS/FORT WORTH LIVING LEGEND PROFESSORSHIP Mr. and Mrs. Michael S. Greene HUBERT L. AND OLIVE STRINGER PROFESSORSHIP IN Mr. and Mrs. William H. Goodwin, Jr. Stephen E. Ullrich, Ph.D. Mr. William J. Goodwin The Greentree Fund MEDICAL ONCOLOGY The Donald G. Goodwin Family Foundation, Mr. and Mrs. Wayne A. Greenwalt Khandan Keyomarsi, Ph.D. BESSIE MCGOLDRICK PROFESSORSHIP IN CLINICAL Inc. Mr. and Mrs. James F. Greer CANCER RESEARCH FRANCES KING BLACK MEMORIAL PROFESSORSHIP FOR Ms. Dorothy Goodykoontz Mr. James H. Greer Jean-Nicolas Vauthey, M.D. CANCER RESEARCH Google, Inc. The Greeting Pen Company Employees of Google Ann Gregory Dimitrios P. Kontoyiannis, M.D. DOUGLAS E. JOHNSON, M.D. PROFESSORSHIP Vijay and Marie Goradia Charitable Foundation Mrs. Charlotte Gregory Christopher G. Wood, M.D. JOHN E. AND DOROTHY J. HARRIS PROFESSORSHIP IN Mr. and Mrs. Daniel P. Gordon Mr. and Mrs. Gray Gregory GASTROINTESTINAL CANCER RESEARCH Mr. and Mrs. Sheldon Gordon Ms. Terri White Gregory Sunil Krishnan, M.D. As of Sept. 1, 2016 Mrs. Caroline Cole Gordy Mr. and Mrs. Clifford H. Greisen Mr. and Mrs. Michael G. Goris Mr. Brett Gremillion Gorlitz Foundation Ltd. Mr. and Mrs. Gaynor G. Gremillion Mr. and Mrs. John W. Gibson Mr. and Mrs. Bobby Gillham Mrs. Judy M. Glass Mr. Nick Gosda and Mrs. Rhonda Gosda Mr. and Mrs. Edward Grenvicz Mr. Rex H. Gibson Mr. Jack Gillis Ms. Rayna Glass Mr. George K. Gosko Mr. John Greytak Mr. and Mrs. Campbell A. Griffin, Jr. Mr. and Mrs. John M. Gidley The Gillson Longenbaugh Foundation Mrs. Judith Glenn Dr. Sandra L. Goss and Mr. Bill N. Goss Jules D. Gosseaux Foundation, Inc. Mr. and Mrs. F. O’Neil Griffin Mr. and Mrs. McHenry Giffin, Jr. Ms. Jamie L. Gilmore and Mr. Garrick Glascock Mr. and Mrs. Lanny G. Glick Ms. Cathy C. Gottesfeld Mr. and Mrs. Guy W. Griffin Mr. and Mrs. Charles J. Giglio Mr. and Mrs. John R. Giordano Mr. and Mrs. Robert F. Glickert Mr. and Mrs. Morris S. Gottesman Linda and John Griffin Mr. and Mrs. Daniel M. Gilbane Ms. Patricia Giordano Mr. and Mrs. Donald Glickman Dr. Robert G. Gottlieb Ms. Merlene Lou Griffin Mr. Adam Gilbert Mr. and Mrs. John F. Gisselbeck GLN Investments LLC Damon and Carolyn Gowan Ms. Christine R. Griffith Mr. and Mrs. Doug Gilbert-Smith Mr. and Mrs. Stan Gitlin Dr. and Mrs. Gary A. Glober Mr. J. Robert Grace, Jr. Billy Royce Griggs Terry M. Giles and Kalli S. O’Malley Mr. and Mrs. Robert T. Givens GlycoMimetics, Inc. Mr. and Mrs. Kenny Grace Mr. Dennis C. Grimm Mrs. Catherine Egan Gilet Mr. and Mrs. Henry A. Gladstone Dr. John R. Gochnour and Mrs. Paula Ruth Mr. J. Martin Grady Mr. and Mrs. Robert H. Grimmer Ms. Mary Gayle Gill Mr. and Mrs. Thomas S. Glanville Gochnour Grady-White Boats, Inc. Mr. and Mrs. W. David Grindle Gill Family Partnership LTD. Mr. and Mrs. Douglas B. Glass Mr. and Mrs. Bill Goddard Mr. and Mrs. Skip Graeber Mr. Tevis Grinstead and Ms. Marilee Wood Mr. and Mrs. Richard F. Gillette Mr. Grayson Glass The Charles B. Goddard Foundation Trust Graeber Foundation Mr. Richard L. Groebel

52 PARTNERS IN MAKING CANCER HISTORY

Billye Spicer Grogan Mr. and Mrs. Charles W. Hall Mr. and Mrs. Ross Harris Mr. and Mrs. Richard W. Heath Ms. Karla Hertzog Mr. Glenn Gros Debbie, Amy and Jessie Hall Mr. Roy D. Harris Mr. Thomas Heathman Mr. and Mrs. Edwin J. Hess Dr. Gail Gross and Mr. Jenard M. Gross Mr. and Mrs. James E. Hall Mr. and Mrs. Titus H. Harris III H-E-B Mr. and Mrs. Earl J. Hesterberg Ms. Mary E. Grosser Mr. Sam H. Hall III Mr. William M. Harris Mr. John M. Hebert Colonel Don Heyden Mr. and Mrs. Irwin Grossman Mr. and Mrs. Willie M. Hall John E. and Dorothy J. Harris Family Mr. and Mrs. Michael D. Hebert Estate of Robert Heyman Mr. and Mrs. Jeffrey Grossman Employees of Halliburton Foundation Mr. and Mrs. Virgil Hebert, Jr. Mr. Russ Hibbeler Mr. and Mrs. Stuart Grossman Halliburton Charity Golf Tournament, Inc. Mr. and Mrs. Bob D. Harrison Mrs. Mary S. Hecht Mrs. Kimberly B. Hibler The Robert and Lynne Grossman Family Halliburton Foundation, Inc. Ms. Elizabeth Harrison Randy and Nancy Hecht Mr. and Mrs. Edward L. Hickl, Jr. Foundation Mr. and Mrs. William P. Hallman Mrs. Evelyn M. Harrison Hector Hall Investments Mr. and Mrs. Alan Hicks Mr. Rakinder Grover Ms. Rebecca Halpern Mr. and Mrs. Judd Harrison Owen and Betsy Hedden Gloria and Ed Hicks Mrs. Rosalind Redfern Grover Mr. John Hambrick Mrs. Mary Ann Harrison Mr. and Mrs. Kirby L. Hedrick Ms. Deborah J. Higbee Mr. and Mrs. Carter S. Groves The Hamill Foundation Mr. and Mrs. John D. Harrower Ms. Adrea D. Heebe and Mr. Dominick A. Dr. Dennis A. Higdon Mrs. Helen K. Groves Mr. and Mrs. Brett L. Hamilton Mr. and Mrs. Robert N. Hart Russo, Jr. Mr. and Mrs. Shayne Higdon Mr. Bob Grubbs J. Stephen Hamilton Mrs. Sylvia Hart Robert & MeiLi Hefner Foundation Mr. Kevin E. Higgins Mr. and Mrs. Justin W. Grubbs Dr. Mary J. Hamilton Mr. and Mrs. William Hart II Mrs. Carol M. Heidbreder Mrs. Sally W. Higgins Mrs. Maureen Grubbs Mr. and Mrs. Robert C. Hamilton Aucoin Hart Foundation Mr. and Mrs. Paul A. Heilman Mr. and Mrs. William G. Higgs Dr. and Mrs. Randy Grubbs Mr. and Mrs. Robert J. Hamilton Mr. and Mrs. James Hartensteiner Hein & Associates LLP The Higgs Foundation Mr. and Mrs. Richard S. Grund, Sr. Mr. and Mrs. Jerrol D. Hamlin Lucy Hartwell Mrs. June G. Heinen Highland Homes Ltd. Mr. and Mrs. James Gruver Mr. Edward H. Hamm Mr. and Mrs. John D. Harvison, Sr. Dr. Peter R. Heinze Mrs. Dorothy H. Hightower GSP Marketing Technologies, Inc. The Nancy and Alan Hamm Charitable The Hasey Foundation Mr. and Mrs. Rodney R. Heisch Hildebrand Foundation Mr. and Mrs. A. R. “Felo” Guerra Foundation, Inc. Mr. and Mrs. James C. Haskins Roger and Anita Heiser of the Ayco Charitable Ms. Mary K. Hildebrandt Guerra Bros. Successors Mr. and Mrs. Royce M. Hammons Ms. Razan A. Hassan Foundation John P. and Mildred O. Hildebrandt Foundation Mr. Craig Guidry Mr. and Mrs. Michael E. Hancock Mr. Fareed Hassen Mr. and Mrs. Harlan Heitkamp Mr. and Mrs. Randy Hiley Mr. and Mrs. Ben A. Guill Ms. Jessica A. Hanfling Hassen’s Department Store Mr. and Mrs. David T. Helffrich, Jr. Hiley Cars Fort Worth Gulf Coast Community Foundation, Inc. Mr. Paul Hanks Mr. Micheal W. Hatch Mrs. Elaine Helfman Hiley Mazda Volkswagen Gulf Stream Marine Mr. and Mrs. Daniel J. Hanley Katherine and Bobby Hatcher Mr. Edwin Heller Al G. Hill, Jr. Mr. Corky Gullo Mr. Robert M. Hanley Mr. Gregory B. Hatchett Mr. and Mrs. Danny Hellmers Anne and Yerger Hill, III Ms. Lora L. Gunn Pete M. Hanna Charitable Foundation Mrs. Claudette A. Hatfield Ms. Glora Helm Mr. and Mrs. B. F. Hill Dr. and Mrs. Jack P. Gunter Mr. Steven R. Hannah The George and Claudette Hatfield Mr. and Mrs. H. Monroe Helm III Ms. Betty J. Hill Mr. and Mrs. Michael Gunter Mr. and Mrs. Steven P. Hannifin Foundation, Inc. The Helmle Shaw Foundation Mr. and Mrs. Gerald S. Hill Roy and Judy Gurley Charitable Foundation Ms. Kathryn A. Hannum Mr. Brian S. Hattendorf Ms. Donna J. Hemphill Mr. and Mrs. Houston Hill Mr. and Mrs. Rodger Gurrentz Hans Brothers Industries Mr. and Mrs. David W. Hattman Mr. and Mrs. John B. Hemphill Ms. Keri Hill Ms. Janet L. Gurwitch Mrs. Mary R. Hansard Mr. Richard A. Hauptfleisch Estate of Gerald Henderson Miss Lyda Hill Mr. and Mrs. Gary R. Gurwitz Ms. Teresa Hansen Richard A. and Wendy S. Hauptfleisch Family Mr. and Mrs. Hal Henderson Lyda Hill Foundation Mr. Jose M. Gutierrez Mr. and Mrs. Joe G. Hanson Foundation Mr. and Mrs. Herman Henderson The Sally F. and James Scott Hill Foundation Mr. Max Gutierrez Happy Grasshopper Mr. Frank R. Hausenfluck Ms. Janice Henderson Mr. and Mrs. David M. Hillberry Mr. and Mrs. Michael W. Guttersen, Sr. Harbin Family Foundation Don and Monica Hausmann Mrs. Michele Henderson The Hillcrest Foundation Guttersen & Company Hardee Family Foundation Inc. Mrs. Suzi Haven Mr. and Mrs. Jim Hendricks Mrs. Linda Hillenburg Mrs. Judith C. Guy Mr. John J. Hardgrave Mr. and Mrs. Robert R. Hawk Mr. and Mrs. Dennis R. Hendrix Ms. Cora L. Hilliard Mr. and Mrs. Richard D. Guyer Mr. and Mrs. Joe S. Hardin Mrs. Constance Hawkins The Dennis and Jennie Hendrix Foundation Ms. Patricia B. Hilliard Ms. Mary F. Gwin Mr. Gary A. Harding Ms. Margaret D. Hawkins and Mr. Fred J. Mrs. Margaret S. Henican Mr. and Mrs. Gerald E. Hillier John Charles Hardison Redeker Don Henley Mr. Steve Hillmer Ms. Maralyn Hare The Hawn Foundation, Inc. Mr. Karl K. Hennessee Mr. and Mrs. James E. Himoff H Mr. O. O. Hare, Jr. Mr. Preston M. Hayes Mr. Jeff Hennis The Hinds Family Mr. and Mrs. Dan Hargesheimer Mr. and Mrs. Cordell H. Haymon Mr. and Mrs. Billy Don Henry Mr. Gilbert C. Hine H & V Equipment Services, Inc. Mrs. Marion S. Hargrove Mr. Houston B. Haymon Mr. Charles L. Henry Wendy and Jeff Hines Mr. Joe M. Haas Mr. William R. Hargrove Mr. and Mrs. William M. Hayner Mr. Gaile M. Henry, Jr. Hines Ms. Fran Haasch and Mr. Rhett Jones Mr. Donald A. Harkey The Reverend and Mrs. George F. Haynes Mr. and Mrs. James C. Henry Ms. Camilla Hinsch Mr. Craig Hacche Kathy S. Harkey Breast Cancer Foundation Mrs. Dorothy C. Hays Mr. John A. Henry III Mr. and Mrs. Ron Hinson Mr. and Mrs. Michael A. Hachtman Mr. and Mrs. Jay D. Harkins Estate of Adrienne M. Hayslip Mr. and Mrs. Milton Henry Ms. Amanda Hinton Ms. Dorothy Hackbarth Mrs. Joann J. Harkins Mr. and Mrs. Johnny P. Hayter Mrs. Pamela I. Henry Mr. Dave Hintz The Hackett Family Mr. and Mrs. John D. Harkins Mr. and Mrs. Lawrence H. Hayward The Henry Foundation Mr. Donald Hintz Dr. Yasmine Haddad Mr. Robert Guy Harley, Jr. L. S. Hayward Foundation Mr. and Mrs. William R. Hensarling Mr. B. Paul Hirsch Mrs. Lana Lowry Hadlock Harley’s Angels, Cruzin’ To Cure HCA Community Relations Margaret Whelan Hensley Mr. Robert F. Hirsch Mr. and Mrs. Joseph A. Hafner, Jr. Mr. and Mrs. Gary H. Harmon HCC Service Company, Inc Mr. and Mrs. Jeffrey K. Hepper Mr. and Mrs. Robert Hirsch Hagopian Family Foundation Mrs. Julie G. Harms HCRA Dr. Kenneth Hepps Mrs. Martha I. Hluchanek Mr. and Mrs. Frank Eugene Hahn III Mr. and Mrs. Alan Harp Mrs. Doris Jean Head Mr. Jeff Herbert Nancy and Jim Hoak Dr. and Mrs. Stephen Hahn Mrs. Harriet M. Harper Mr. and Mrs. Joseph H. Head, Jr. Ms. Karen Hering Roy Hobbs Foundation Mr. and Mrs. John H. Haire Ms. Donna Harr Head for the Cure Foundation Mr. and Mrs. Lawrence Shepley Hermann Mr. and Mrs. Paul W. Hobby Mrs. Ramona G. Hairston Mr. Ronald D. Harrar Ms. Marjorie Headd Mr. and Mrs. Fernando M. Hernandez Hobby Family Foundation Hairy Cell Leukemia Foundation Mr. and Mrs. Wilson Harriman Mr. and Mrs. Arval D. Headrick Mr. and Mrs. Hector M. Hernandez Mrs. Diana Hodge Mr. Mark E. Hakemack Mr. and Mrs. David A. Harris Mrs. Mary Ray Heard Mr. Jose Hernandez and Mrs. Evette Mock- Margaret and Jerry Hodge Mr. and Mrs. Thomas C. Halbouty Mr. and Mrs. James P. Harris Ms. Katy Hearn Hernandez Mr. and Mrs. Mark C. Hodges Mr. Arthur Hale Jim and Jan Harris Mr. Michael Hearne Mrs. Linda P. Hernandez Mr. Ernest F. Hodson Mr. and Mrs. James Edward Haley Mr. and Mrs. Michael H. Harris Heart Sing Foundation Mr. and Mrs. H. David Herndon Mr. Karl Hoepfner Ms. Mary Nell Haley Mr. and Mrs. Richard L. Harris Mr. and Mrs. Jesse B. Heath, Jr. Mr. and Mrs. David T. Herr Mr. and Mrs. Ervin Hofferek Ms. Carol D. Hall Mr. and Mrs. Robert B. Harris Laurie and Dennis Heath Mr. and Mrs. Homer H. Hershey Mr. Hugh H. Hoffman

53 MD Anderson Annual Report

Mr. Robert B. Hoffman Houston Galleria Retail Dr. Christopher W. Huston Mr. Max W. Jacobs Mr. and Mrs. James A. Johnson The Hoffman Foundation Houston Jewish Community Foundation Mr. and Mrs. Oliver Hutaff Emma Jacobs Breast Cancer Foundation Mrs. Jing Johnson Mr. and Mrs. Dan Hogan III Houston Pi Beta Phi Foundation Ms. Nina C. Hutton Mrs. Joanie Jacobsen Ms. Kimberly Johnson Mike Hogg Fund Houston Racquet Club Mr. Don Hyatt Mr. and Mrs. Paul Jacobsen Mr. and Mrs. Leslie W. Johnson Mr. and Mrs. Forrest E. Hoglund Houston Racquet Club Women’s Association Hyundai Hope on Wheels Mr. and Mrs. Norman K. Jacobson Luci Baines Johnson and Ian Turpin The Hoglund Foundation Houston Shoe Hospital Hyundai Motor America Catherine H. Jacobus Estate of Marilyn E. Johnson Dr. Deborah Hohn Houston Texas Fire Fighters Federal Credit Mr. and Mrs. A. J. Jacques Ms. Melody A. Johnson Ms. Phyllis S. Hojel and Mr. John Mascotte Union Jaga Motor Co., Inc Mr. and Mrs. Neil R. Johnson Mr. and Mrs. Christopher T. Hoke Houston Tri Delta Philanthropies, Inc I Mr. and Mrs. Michael V. Jaggers Mr. Ray Johnson MaraLessa and Alter Holand The Houstonian Hotel, Club & Spa JAH Partners Mr. and Mrs. Robert W. Johnson Dr. and Mrs. Geoffrey S. Ibbott Mrs. Arlene M. Holden Mr. Souren A. Hovsepian The Jakubik Family Mr. and Mrs. Scot W. Johnson IBC Bank Don L. and Julie Holden Foundation Mr. and Mrs. Bill Howard Mr. and Mrs. J. E. Jalufka Mr. and Mrs. Shelton C. Johnson, Sr. The IBC Network Foundation Mr. and Mrs. Tim K. Holder Mr. and Mrs. Bill J. Howard Mr. and Mrs. Frank M. James Mr. and Mrs. Tom Johnson IBE Trade Corp. Mr. and Mrs. Glen Z. Holender Mr. and Mrs. Bo Howard Mrs. Lynn Karroll James Mr. and Mrs. Walter E. Johnson IBM Employee Services Center Mrs. Lisa L. Holifield Laura and William Howard Mr. and Mrs. Richard L. James Mr. and Mrs. William F. Johnson IBM International Foundation Mr. and Mrs. Britton Holland Mrs. Mary E. Howard Raymond James Charitable Endowment Fund Mr. William T. Johnson Ideal Partners Management Group LLC Dr. and Mrs. Robert C. Hollander Mr. Randall L. Howard Jamie’s Hope Johnson & Johnson Foundation Mr. Robert Ideus Ms. Barbara Holley Mr. Michael W. Howe Jane Wallace Charitable Fund The Johnson Family Foundation IGT Global Solutions Mr. and Mrs. Charles E. Hollier Dr. and Mrs. Richard J. Howe Mrs. John C. Jansing J. Howard & The Honorable Brenda LaGrange Illinois Tool Works Foundation Ms. Susan M. Hollingsworth Bob and Aubyn Howe Foundation Jansing-Cook Foundation Johnson Family Fund Mr. and Mrs. Andy Immroth Mr. John C. Holloway Mr. and Mrs. Hilton H. Howell, Jr. January Baby Cakes Inc. Chris CJ Johnson Foundation Barbara F. Immroth, Ph.D. Ms. Patti Jones Holloway Mr. and Mrs. Peter Paul Howell Mr. and Mrs. Emil Edward Jaster Christine and John Johnston Impact Fulfillment Service, Inc. Ms. Ellen L. Holman Robert and Catherine Howell Eric Javits Family Foundation Mr. James J. Johnston, Jr. Indian Industries, L.P. Mr. and Mrs. Richard Holmes Howl At The Moon Promotions Ltd. Co. Jaxon’s F.R.O.G Foundation Estate of Jerald D. Johnston Industrial Alloy Fabrication, Inc. Mr. and Mrs. Thomas J. Holmes, Jr. Mr. Ben Hoyes Dr. and Mrs. Thirumalairaj Jayakumar Mr. and Mrs. John Bishop Johnston Industrial FFA Mr. and Mrs. Conrad T. Holt Andrew and Ingrid Hoyle Mr. and Mrs. L. Weldon Jaynes Ms. Jo-Lynn Johnston Inflammatory Breast Cancer Foundation Mr. and Mrs. Jason B. Holton Dr. and Mrs. Gaylord M. Hoyt Jazz Pharmaceuticals, Inc. Mr. and Mrs. Mark F. Johnston Input Creative Studio LLC Mr. and Mrs. Michael Holton Mrs. Phyllis Hubbard The JB Ashtin Group, Inc. Mrs. Virginia H. Jolly Mrs. Ashley Inselman Mr. and Mrs. Stephen B. Holton Mr. Frederick N. Hubbell JBA Houston Foundation, Inc. Mr. and Mrs. A. V. Jones, Jr. Insulation Products Corporation Mr. and Mrs. Joe Holyfield Mr. and Mrs. Gerald S. Huchital JBA Investments, LTD. Colonel Allan M. Jones InterActive HealthCare, Inc. Dr. and Mrs. Kenneth L. Homann Mr. and Mrs. Gary Huckabay The JBD Foundation Mr. Clark Jones The Interfin Companies LP Homeowners Asoociation of Heritage Mr. Donald Hudler JBJ Foundation Inc. Mr. and Mrs. Jeffrey A. Jones International Connections of Houston Ranch Inc. Estate of Adeline D. Hudson Mr. Michael J. Jeansonne Mr. and Mrs. Jerry W. Jones Intruder Alert Systems, Inc. Mrs. Gail Homerding Mr. and Mrs. Bill F. Hudson Mrs. Tiffany Jedlicka Mr. and Mrs. Jon Rex Jones Intuitive Surgical William E. and Audrine Honey Foundation, Inc. Mr. Chris Hudson Jefferies & Company, Inc. Mr. and Mrs. K. C. Jones Dr. Katie D. Irani Honeywell International Ms. Patricia O. Hudson and Mr. Hatcher E. Mr. Donald R. Jefferis Mr. Kirk G. Jones Mr. and Mrs. Jerry E. Irwin Dr. and Mrs. Waun Ki Hong Chalkley Ms. Carol T. Jeffrey Mr. and Mrs. Merritt Jones Dr. A. Christine Isaac and Mr. William Isaac Mr. and Mrs. J. Kyle Hooper Mr. and Mrs. Warren J. Hudson Estate of William R. Jeffryes Mr. Michael Jones Mr. Jerry Isackson Mr. and Mrs. Milton L. Hooper, Jr. Mr. and Mrs. Bert L. Huebner Mrs. Jui-Chu Jen and Mr. Kai-Lo Mao Mr. and Mrs. Paul K. Jones Island Operating Company, Inc. Mr. Carl H. Hoover Mr. and Mrs. James R. Huffines Ms. Linda Jenkins Paul and Marilyn Jones Ms. Cynthia J. Isley The Hope Foundation Mrs. Sydney Huffines Mr. and Mrs. Ricky Jenkins Mr. Raymond Jones The Lawrence Israel Family Foundation Mr. Bob C. Hopkins Ms. Terry Huffington and Dr. Ralph Dittman Mr. Svend A. Jensen Mr. and Mrs. Raymond A. Jones Mr. and Mrs. Verne G. Istock Mr. and Mrs. David L. Hopkins Ms. Catherine E. Huffman Jewelers of Louisiana, Inc. Mr. Roland Jones, Jr. Ms. Kim D. Istre Estate of Helen H. Hopper Mr. and Mrs. Gary R. Huffman Nancy Glanville Jewell Mr. and Mrs. Stephen R. Jones Dr. Cristina Ivan Vicki and Dennis Hopper Mr. Gerald E. Huggs Mr. and Mrs. Robert V. Jewell Mr. and Mrs. Wayne Jones Mr. and Mrs. Jose Ivo Mr. and Mrs. James P. Horan Mr. and Mrs. Gordon L. Hughes Jewish Communal Fund Gene & Jerry Jones Family Foundation The Ivy Foundation Mr. and Mrs. Dan Hord, III Ms. Liz Hughston Jewish Federation of Greater Atlanta The Dodge Jones Foundation Hord Foundation, Inc. Mr. and Mrs. James R. Hull Jewish Federation of St. Louis Ms. Juliet H. Jones-Moss Mr. and Mrs. David M. Horgan Mr. and Mrs. Jeffrey O. Hull J Mrs. Fauzia Jillani Mrs. Renee B. Jongebloed Hormel Foods Corporation Mr. Riter C. Hulsey Ms. Judith Jimenez Mr. John E. Jonietz Mr. Robert Horner Mr. and Mrs. William H. Hulsey, Jr. J & E Leasing Properties LTD. Mr. Julio M. Jimeno Mr. and Mrs. William F. Joplin Mr. and Mrs. Merritt Horrell, Jr. Mr. and Mrs. James G. Humphrey J. Schneider and Associates, Ltd. JJR Enterprises Mr. and Mrs. John W. Jordan, II Ms. Jeanne A. Horrigan Estate of John W. Hunt J.O. Alvarez, Inc. JM Enterprises, Inc. Estate of Joyce M. Jordan Mr. and Mrs. John Horstman Mr. and Mrs. T. Elwood Hunt Ms. Irene Jablonsky Joe Basil Chevrolet, Inc Mrs. Paula Jordan-Foster and Mr. David Foster Mr. and Mrs. Henry Hortenstine The Woody and Gayle Hunt Family Foundation Jack Hilliard Distributing Co., Inc. Joey’s Wings Mr. Wayne Joseph Mr. Richard J. Horvath Mr. and Mrs. Gerhart E. Hunter Alan and Cristina Jackson Mr. and Mrs. Thomas T. Johansen Ms. Karen Pines Josephs Mr. David C. Houck Mr. and Mrs. Jasper E. Hunter Barbara Uscian Jackson John 3:16 Mr. and Mrs. Lenoir M. Josey II Mrs. Dorothy Knox Houghton Mrs. Miranda Hunter Mr. and Mrs. Carl R. Jackson Mr. and Mrs. Terry Johns Employees of JPMorgan Chase & Co. Houseman/Wilkins Ophthalmological Mr. and Mrs. Robert C. Hunter Mr. and Mrs. James M. Jackson Johns Marrs Ellis & Hodge LLP JSD Capital LLC Foundation Hunter Marine Mr. and Mrs. John C. Jackson II Ambassador Brenda LaGrange Johnson and J. Mr. Lenin Juarez Mr. Daniel T. Houston Mr. and Mrs. Richard O. Hunton Sr. (Hunton Mr. Karl W. Jackson Howard Johnson Mrs. Diane Judah-Mayberry Mr. James R. Houston Group) Mr. Kenneth R. Jackson Mr. and Mrs. Darrel D. Johnson Mr. and Mrs. Michael S. Juden Houston Baptist University Barbara and Charles Hurwitz Ms. Leslie Jackson Mr. David J. Johnson Mr. David Judkins Houston Chapter Oncology Nursing Society Susan and Martin Hurwitz Dr. Paul A. Jackson Mr. and Mrs. David M. Johnson Julian Gold, Inc. Houston Christian High School Hurwitz Family Foundation Mr. Thomas I. Jackson Ms. Ellen K. Johnson Ms. Aimee Jungman Houston Endowment Inc. Mr. and Mrs. Syed S. Hussaini Jackson Sjoberg McCarthy & Townsend, LLP Mr. and Mrs. Eric Johnson The Junior League of Houston, Inc. Houston Foam Plastics, Inc. Mr. and Mrs. William L. Husted Jackson-Merkey Contractors, Inc. Mr. and Mrs. George H. Johnson Ms. Rebecca B. Junker

54 PARTNERS IN MAKING CANCER HISTORY

Estate of Johnathan Martin Juricek T. Mark Kelly The Kinkaid School Mr. and Mrs. Michael Konrad Mr. and Mrs. Keith Landsness Mr. Donald Jurow Mr. and Mrs. John W. Kelsey Mr. Glenn V. Kinsey Dr. Dimitrios P. Kontoyiannis Mr. and Mrs. Bryan Lane JWC Covenant, Inc. Kelsey Research Foundation Mr. Joseph Kinsey Mr. Rollins M. Koppel Mr. Eric S. Lane Garth and Jean Kemp Mr. and Mrs. Gene L. Kirby Dr. and Mrs. John T. Korinek Ms. Mary Lane Mr. Stuart H. Kemp Mr. and Mrs. Jack L. Kirby Mr. and Mrs. Joshua M. Korman Mr. and Mrs. Kenny Lang K Ms. Nicholas I. Kemsley Ms. Janet Kirk Ms. Jane S. Korn Ms. Stephanie Lang The Kenan Advantage Group, Inc. Mr. and Mrs. John P. Kirk Mr. Marvin R. Korn Mr. and Mrs. John J. Langdon Kadiki Creative, Llc Kendra Scott Design, Inc. Mr. and Mrs. G. C. Kirkmyer III Dr. Barbara Kornblau and Dr. Donald J. Mr. and Mrs. Edmond J. Langhetee, Jr. Sir Michael and Lady Kadoorie The John G. and Marie Stella Kenedy Memorial Dr. Rickey C. Kirkpatrick and Rev. Kathy Newell Kornblau Mr. Gerald P. Langlykke Mr. and Mrs. Jeremiah R. Kafka Foundation Kirkpatrick The Kort Family Mr. David M. Langston Mr. and Mrs. Alan R. Kahn Mr. and Mrs. James C. Kennedy Kissick Family Foundation Mr. and Mrs. Harold G. Kotler Thomas H. Lanier Foundation Mr. and Mrs. W. Barry Kahn Mr. and Mrs. Ronald E. Kennedy Ms. Nancy Kissinger Mrs. Charlene F. Kovarik I. A. Lanier-Goodman Foundation Mr. and Mrs. Robert M. Kain Mr. Steve Kennedy and Mrs. Mary Ellen “Mel” Travis and Susan Kitchens Mr. Gary Koverman Mr. and Mrs. Charles Lankford, Jr. Mr. Grant Kaiser Kennedy Estate of Mary B. Kite Ms. Rosemary E. Kowalski Mr. Leonard F. LaNoue Mr. Ridge Matthew Kaiser Mr. W. Elton Kennedy Mr. Robert J. Kite Mr. Majid Koza Mr. James M. Lapeyre, Jr. Mr. and Mrs. Kenneth W. Kaltwasser J. C. Kennedy Foundation, Inc. Mr. Albert Kittle KPMG Foundation Mr. and Mrs. Pierre F. Lapeyre, Jr. Mr. Parviz Kamangar W. Elton Kennedy Foundation Mr. Jeremy Klapprodt Donna E. and Frank J. Kracmer Mr. and Mrs. Jaime G. Lara Parviz Kamangar Charitable Foundation Ms. Jill F. Kenney Mr. and Mrs. Roger L. Klasse Tom Kraft Ms. Lucy D. Lardner The Curt Kamradt Family Ms. Louise Kennon Mr. John C. Klaus Mr. Gerald L. Krakaur Estate of Kay D. Laro Mrs. Virginia Lee Kanaly Keown Charitable Trust Mr. and Mrs. Terry A. Klebe Mr. and Mrs. Michael W. Krall Mr. Roderick S. Laseter Mr. Spikes Kangerga Mr. and Mrs. Roger L. Kesseler Mr. and Mrs. Richard M. Kleberg III The Gladys and Lee A. Krause Jr. Fund of the Janiece and Stephen Lasher Kansas City Southern Industries, Inc. Mr. Barry R. Kessler Robert J. Kleberg, Jr. and Helen C. Kleberg Lutheran Community Foundation Mr. Anthony Lasita Steven C. and Lori Feinberg Kany Mr. Mort Kessler Foundation Mr. John H. Krehbiel, Jr. Mrs. Linda M. Last Dr. Asha S. Kapadia Mr. and Mrs. Paul D. Kestler Kleemeier Family Fund Kay and Fred Krehbiel Latattore Foundation Mr. and Mrs. Marvin Kaplan Mr. and Mrs. Siddharth Keswani Alan A. and Janetta B. Kleier Mr. Chuck Kreutz Mr. Chester Lathem Kaplan Family Foundation Dr. Charles B. Key Mr. Barry J. Klein Ms. Vivian Kreutzberger Ms. Pamela A. Lathem Mr. Ozden M. Karakurt, Sr. Mr. Clifton W. Key Mr. Donald F. Klein Mr. and Mrs. William Kreykes Mr. Bruce E. Latimer Ms. Seema V. Karande Mr. and Mrs. J. Scott Key In honor of Mel Klein, Ernie Cockrell and Dr. Mr. James D. Kruciak Tim L. Laudadio Mrs. Geraldine Karkowsky Larissa Meyer and her team KeyBank National Association Dr. Iris M. Krupp Mrs. Helen H. Laughery Mrs. Robin L. Karlik Mr. and Mrs. Melvyn N. Klein Mr. and Mrs. Howard W. Kiatta Mr. and Mrs. Paul W. Kruse Ms. Erica Laughlin Ms. Jean L. Karotkin Mr. and Mrs. Michael L. Klein Ms. Kelli Kickerillo and Mr. Todd Forester Mr. Ken Kruss Mr. and Mrs. John F. Lauletta Mr. and Mrs. Ronald P. Kasik Mr. and Mrs. Thomas Klein Kickerillo Companies Mrs. Helen H. Kuester Ms. Yolanda M. Laurel and Dr. Richard D. Mr. Bruce M. Kasper Mr. and Mrs. Craig S. Kiefer Alvin A. and Roberta T. Klein Trust Mrs. Desiree G. Kuether Swope Kasting, Kauffman & Mersen, PC Kiefer Mazda Mr. Martin Kleinbart Mr. Andrew E. Kurie Ms. Leigh Lausen Mrs. Darrell J. Kastner Mr. and Mrs. Matti Kiik Mr. and Mrs. John C. Klemm Mr. and Mrs. Neal Kurn Mr. Jeff Lautt Mr. and Mrs. Bernard H. Kastory Mr. Earl J. Kilbride Mr. and Mrs. William Philip Kliewer Kurtz Designs Frances Ann Lavergne Kastory Family Foundation Mr. Gary Hartman Kilgore Mr. and Mrs. Jan M. Klinck Mr. Robert R. Kurz Mr. and Mrs. Kase L. Lawal Mrs. Abe M. Katz Ms. Mary K. Kilgore Klinck Foundation, Inc. Michael Kutsch and Tammy Coselli Mrs. Sydney Touchstone Lawder Mrs. Doris Brand Katz John and Barbara Killian Thomas P. Kline KW Cares Mr. and Mrs. Bill L. Lawler The Katz Foundation Mr. and Mrs. J. Reese Killion Mr. Mackie L. Klingbeil KWS Foundation Mr. and Mrs. C. Berdon Lawrence Mr. George Kaufman Ms. Suzanne L. Kilpatrick Mrs. Mary Kloc Ms. Linda J. Kyle Mr. and Mrs. Michael A. Lawrence Mrs. Shirley Kaufman Mr. and Mrs. John Z. Kimberlin, Jr. Ms. Guta Klug Dr. and Mrs. Demos T. Kyrazis J. M. Lazarus Foundation Sylvia and Dick Kaufman Mr. and Mrs. Richard H. Kimberly KMG Consulting, LLC Mr. and Mrs. William J. Kyte Lazy Two Cattle Company Kaufman Foundation Mr. and Mrs. Sidney Kimmel Mr. and Mrs. Corey L. Knapp LBJ Family Foundation Kavanagh Family Foundation Angela and Bob Knauss Sidney Kimmel Foundation L Ms. Dianne D. Leach Kay R. McMillan Investments Mr. and Mrs. Henry C. Kimmey Mr. and Mrs. Don R. Knauss Mr. and Mrs. Geoff Leach Ms. Dena Kaye Ms. Amy Kincaid Patricia L. Knebel Memorial Fund of The The Honorable and Mrs. Howard H. Leach Pittsburgh Foundation Labatt Food Service Danny Kaye and Sylvia Fine Kaye Foundation Kinder Foundation Mr. and Mrs. Timothy A. Leach Mr. Daniel Knight Mr. and Mrs. Daniel M. Lacaci The Kayser Foundation Kinetica Partners LLC Leaddog Marketing Group Ms. Sherry L. Knight Mr. and Mrs. Robert A. Lacey Mr. and Mrs. Joseph S. Kazda Mrs. Amelia S. King Mr. and Mrs. Ralph Leatherman Clifford L. Knight Foundation Mr. and Mrs. Todd E. Lachenmyer Dr. and Mrs. Michael J. Keating Ms. Audria Borders King Mr. Lance A. LeBlanc Mr. and Mrs. Terry G. Knighton Ms. Christine E. Lacke Mrs. Donna K. Keeling Mr. and Mrs. Jerry Allan King Mr. and Mrs. Marc LeBlanc Mr. George W. Knorr, Jr. Kent Lacy Mr. and Mrs. Douglas H. Keeling Mr. and Mrs. Luther King Sandra and Roger LeBlanc Mr. and Mrs. Wyck A. Knox, Jr. Mr. and Mrs. Bob Ladd Dr. Ralph Keen Mr. Mike King Mr. and Mrs. Joe Leblow KOA Care Camps Mr. and Mrs. Frank A. Ladd The Honorable and Mrs. James L. Keffer Mr. and Mrs. Rex C. King Steven and Deborah Lebowitz Foundation Mr. and Mrs. Randall Kob Ms. Patricia Ladd KEG 1 O’Neal, LLC Ms. Sheeran H. King Mr. and Mrs. Lewis B. Ledlow Mr. Mark Kobmann Ladies Leukemia League, Inc. Estate of Mildred H. Keith Mr. and Mrs. Terry King Mr. and Mrs. Dwight J. Ledoux Mr. David H. Koch Mrs. Kandace Ladis Mr. and Mrs. Herbert D. Kelleher Mr. Thomas M. King, Jr. Amy and Gentry Lee Jeff and Gail Kodosky Ms. Neda Ladjevardian Mr. Keith Keller King Aerospace Inc. Mr. and Mrs. Bradley A. Lee Mr. and Mrs. Clinton H. Koerth Mr. Mats B. Lagmanson Ms. Kimberly C. Keller Rex and Marillyn Lee King Family Foundation Ms. Catherine Lee Mr. and Mrs. Donald R. Koester Lake Travis United Methodist Church Mr. Richard P. Kelley King Ranch, Inc. Mr. Chul-Jae Lee Mr. Edwin C. Koh The Lakefield Family Foundation Mr. and Mrs. James W. Kellogg, Sr. Mr. and Mrs. Ken B. Kingon Mr. and Mrs. Eddie L. Lee Mr. and Mrs. Gary A. Kolstad CJ Lammers Dr. and Mrs. Charles R. Kelly Ms. Jane C. Kingsbury Mr. and Mrs. Edward T. Lee Susan G. Komen® Mr. and Mrs. Dale Land Dr. Michael Kelly Tim and Jan Kingsbury Mr. Ian Lee Mr. J. M. Komes Landon Homes, LP Mr. Patrick Kelly The Sally M. Kingsbury Sarcoma Research Mr. and Mrs. Jack G. Lee Komes Foundation Mrs. Dolores Landrum Mr. and Mrs. Richard J. Kelly Foundation, Inc. Mr. and Mrs. James H. Lee Susie and Pat Kelly Mr. Oliver D. Kingsley, Jr. Mrs. Janice A. Konarik Mr. and Mrs. Les J. Landry Landsdowne-Moody Company LP Mr. and Mrs. Jim Lee

55 MD Anderson Annual Report

Mr. Quincy Lee Dr. and Mrs. Charles A. LeMaistre Leukemia & Lymphoma Society Linebarger Goggan Blair & Sampson, LLP Ms. Elizabeth Luera Mr. Quincy J. Lee Dr. and Mrs. Mark L. Lemmon Leukemia Research Foundation Mr. and Mrs. Jonathan S. Linker Ms. Janet M. Luiz Mr. Robert Lee, Jr. Mr. and Mrs. Richard W. Lemmons Leukemia Texas, Inc. Dr. Emma L. Linn Lumina Foundation Mr. and Mrs. William Gentry Lee, Sr. Mr. Kenneth W. Lemons Mr. and Mrs. J. Waymon Levell Linn Energy The Luminescence Foundation, Inc. Dr. Norman E. Leeds in Honor of Ms. Bette Mr. and Mrs. Charles R. Lenert Mr. Daniel Leventhal Michael C. Linn Family Foundation Lunch Mony, Inc. G. Leeds Mr. and Mrs. John H. Lenihan Mr. John Lever Ann Noel Lisenby Mr. Wallace L. Lundgren, Sr. Dr. and Mrs. Peter J. Leeson Mr. and Mrs. Craig R. Lentzsch Charles and Margaret Levin Family Foundation Mr. and Mrs. Joseph Listengart Lung Cancer Research Foundation Legacy Christian Academy Mr. Charles A. Lenzie Mr. Jerome Levine Mr. and Mrs. Joel M. Litman LUNGevity Foundation Legacy Energy Company Mr. Jeremy Leonard Mrs. Lee Levit Mr. and Mrs. Keith G. Little Ms. Jean R. Lunt Dr. Randy J. Legerski Ms. Marty V. Leonard Rochelle and Max Levit Mr. and Mrs. Ronald E. Little Mr. and Mrs. Ted W. Lusher Lehigh Cement Company Leonard-Meron Biosciences, Inc. Milton and Lee Levit Family Mr. Brian Littleton Mr. and Mrs. Homer L. Luther, Jr. Mr. and Mrs. David H. Lehman Mr. and Mrs. Richard J. Leroux Mr. and Mrs. Dan Levitan Franna and Ted Litton Luther King Capital Management Lehman Family Charitable Foundation Mr. Rob Leslie Mr. and Mrs. Irwin L. Levowitz Mr. and Mrs. Billy Liu Mr. Bill Luyties Mrs. Selma Leiber Mrs. Mary Vaughan Lester Mr. and Mrs. David Levrier Mrs. Jean C. Liu LVM Holdings LP Dr. Janet Elisabeth Leigh The Lester Family Foundation Ms. Carol R. Levy The LLEE Foundation Mr. and Mrs. Robert W. Lydick Kathleen L. and Edward B. Leinbach Mr. and Mrs. Robert Lestz Judith M. and Irwin L. Levy Locke Lord LLP Mrs. Rosemary K. Lykos Mr. Michael R. Levy Lockheed Martin Employees Political Action Ms. Patricia S. Lyle Mr. Ralph B. Levy Committee Mr. and Mrs. Jeffrey L. Lyman Mr. Shimon Levy Lockheed Martin University Matching Gift Lymphoma Research Foundation Advance Team The Meyer Levy Charitable Foundation/Rachel Program Mr. Francis L. Lynch Levy Goldberg, Mara Elizabeth Levy, Tobin Mr. John W. Lodge III Deborah A Lyon The following people comprise a volunteer leadership board Janel Levy & Michael R. Levy Ambassador John L. Loeb, Jr. LyondellBasell Industries focused on advancing MD Anderson’s mission to eliminate Mr. and Mrs. Chris W. Lewis Nancy B. Loeffler Mr. Allan R. Lyons Michael and Tina Loehr cancer through community-based initiatives centered on basic Mr. and Mrs. Griffith T. Lewis Mr. David F. Lyons Harriet Yoshida Lewis and I. Norman Lewis Mr. and Mrs. G. W. Loewenbaum Toni and David Lyons Charitable Foundation science research, education and cancer prevention. Mr. and Mrs. Jack Lewis Mr. John T. Loftus Mrs. Kasey Asarch Mr. Barry R. Kessler Mr. Jerome Lewis Mr. Christopher S. Lolley Mr. and Mrs. Jerome F. Lewis Mr. Dennis Lombardo M Mrs. Ashli R. Blumenfeld Ms. Kelli Kickerillo Mr. and Mrs. Michael A. Lewis Mr. and Mrs. Dennis F. Loner Mr. William R. Bobbora Mr. John W. Kraft Mr. and Mrs. Robert F. Lewis Ms. Dana Long M2 The Agency, Inc. Mr. Rodney R. Lewis Ms. Martha Long Mr. Tamotsu Mabuchi Mr. Brian Carney Mrs. Lisa D. Kurtz Mrs. Rupert S. Lewis Mr. and Mrs. Meredith J. Long Mr. and Mrs. C. Robert Mace Ms. Carolyn Chachere Mr. Gentry Lee, Jr. Lewis Energy Group Mr. and Mrs. Stacy D. Long Ms. Vanilla Macias-Rodriguez Mr. and Mrs. John Mack Ms. Nell F. Connally Mrs. Karissa R. Ma Richard Spencer Lewis Memorial Foundation Longhorn Lexington Livestock Commission Mr. and Mrs. Harry J. Longwell/Longwell Mr. Andrew MacKechnie Mrs. Rachel Cruz Auwarter Mr. Chuck Matthews Mr. David W. Ley Family Foundation Mr. Nick MacKenzie Mrs. Jennifer Womble Daniels Mrs. Caroline C. McAllister Ley Development Company, LLC Mr. and Mrs. Cecil J. Looke Mr. Bruce G. Macklin Ms. Angela Li Mrs. Elia Lopez Mr. and Mrs. John Phillip Madden Mr. Daniel G. Darling Ms. Sterling McDavid Yinquan Li Dr. and Mrs. Frank W. Lopez Mr. and Mrs. Robert R. Madden Mr. Danny David Mrs. Carrie Chamberlin Miller Employees of Liberty Mutual Mr. Dan Lorance Mr. and Mrs. Steven H. Madden Mr. Richard E. Lore, Sr. Mr. Melvin H. Madewell Mrs. Holly B. Deshields Mrs. Kristen C. Nix Mr. Brian L. Libman Mr. and Mrs. Robert M. Lichten Mr. and Mrs. Francisco A. Lorenzo Mr. John W. Madigan Ms. Margaret G. Doyal Mrs. Margye Northington Mr. and Mrs. Cary Lichtenstein Estate of Sara P. Loshak Mr. and Mrs. Richard L. Madison Mr. and Mrs. Andrew Maebius Mrs. Ann Margaret H. Dudley Mr. J. C. Pace III Ms. Frann G. Lichtenstein Mr. and Mrs. Mitchell T. Lou Frann Gordon Lichtenstein Foundation Mrs. Patricia M. Loucks Mr. and Mrs. Steve F. Mafrige Mr. James T. Dudley Mrs. Sharon M. Parker Mr. and Mrs. Don B. Lichty Loucks Family Foundation Mr. and Mrs. Hubert E. Magee, Jr. Mr. Robert A. Elliott Mrs. Amy G. Pierce Mr. and Mrs. Martin J. Lide Mr. Robert D. Loughney Mr. Mark Magee Mrs. William C. Liedtke, Jr. Louisiana Machinery Co. Mr. Frank C. Maguire, Jr. Ms. Christine M. Falgout Mrs. Lauren Loeffler Powers Mr. and Mrs. Kenneth J. Lien Mr. and Mrs. Jeff B. Love Mr. Jim Mahler Ms. Kimberly A. Falgout Mr. Brendon C. Quick Mr. Jeffrey A. Liggett The Jeff B. and Katherine B. Love Foundation Mr. and Mrs. Jeffrey S. Mahlmann Ms. Alice Loveless Mr. Brian A. Mahoney Mrs. Courtney Hill Fertitta Mr. Anson M. Reilly Mr. and Mrs. Don Lightfoot Julie Lightfoot, Discovery Toys Mrs. Jane Maury Lovitt Mr. Glen Maikranz Jr Mrs. Louisa Fikes Mr. Michael C. Rodriguez Mr. Vincent M. Lightfoot Ms. Martha Low Mr. Edward F. Malanda Mrs. Eleanor H. Gilbane Mrs. Jamille W. Ruebsahm Captain Thomas N. Lightsey, Jr. Ms. Margaret Lowden Mr. Edward J. Malek Tom & Betty Lightsey Family Trust Mr. Dennis Lowe Marlene A. and Frederic V. Malek Mrs. Kristin C. Hamilton Mr. Thomas Holden Rushing Lila Construction Company Mr. and Mrs. Doug Lowe Mr. and Mrs. Kevin Maley Ms. Susan Oliver Heard Mrs. Heather Russo Mr. Byung K. Lim The Lowe Foundation Malibu Floors Mr. and Mrs. Brent L. Lowery Mr. and Mrs. Jean Malo Mr. Bradfield W. Heiser Mrs. Laine Santamaria Mrs. Huaying Lin Ms. Nora Linares-Moeller and Mr. Mike Mr. and Mrs. Paul B. Loyd, Jr. Bob and Diane Malone Mrs. Mullaney Nichols Heiser Dr. Jennifer Segal Moeller The Loyd Charitable Foundation Mr. and Mrs. M. S. Mandell LPL Financial Services Mr. and Mrs. Moez S. Mangalji Mr. David T. Herr Ms. Robyn Stringfellow Linbeck Group, LLC Mr. Robert D. Linder, Sr. LSI Industries Inc. Ms. Zein B. Mangalji Mr. Brandon K. Holcomb Mrs. Claire C. Thielke George B. Lindler Foundation Mr. Guanqiu Lu Mangen Family Charitable Foundation Mr. Ryan Hughes Mrs. Ashley Weathers Mr. and Mrs. Steven J. Lindley Mr. and Mrs. Sheldon Lubar The Harry T. Mangurian, Jr. Foundation, Inc. The Marty Lindley Foundation, Inc. The Lubrizol Foundation Mr. and Mrs. Harendra M. Mankodi Mrs. Jocelyn Johnson Dr. Neshat Yazdi Mr. Robert D. Lindner, Sr. Mr. and Mrs. Mark C. Lucas Mr. and Mrs. Robert M. Manley Linear Controls, Inc. Mrs. Seymour Luckoff Ms. Elizabeth Mann Mrs. Kim Johnson As of Dec. 1, 2016

56 PARTNERS IN MAKING CANCER HISTORY

Ms. Kathryn N. Manning Lucinda and Bill Matthews Mr. and Mrs. Donald G. McCoy Mr. and Mrs. Leo R. McLean Mrs. Merna W. Metz Mr. and Mrs. Greg Manocherian Mr. and Mrs. Steve Mattingly The McCrea Foundation Ms. Dianne A. McLoughlin James H. and Jill Metzger Ms. Patricia M. Mansfield Mrs. Phil Matza Mrs. Dorothy M. McCreath Mr. Douglas McMillan Mr. Brian Meuth Manteca Rotary Club Mr. and Mrs. Richard H. Matzke Mrs. Barbara L. McCrocklin Mr. and Mrs. Gordon McMillan Charlie and Virginia Meyer Mrs. Nancy C. Manweiler Mrs. Dawna Mauldin Mr. and Mrs. Andrew D. McCullough, Jr. Mrs. Kay R. McMillan Mr. and Mrs. Derrick R. Meyer Mr. Wolfgang Manz Mrs. Patricia M. Maxin Ralph H. and Ruth J. McCullough Foundation Don & Colletta McMillian Foundation Mr. George Meyer Ms. Jessiele C. Manzano Ms. Anne Maxwell Mr. Glenn McCutchen Dr. Jeanie B. McMillin-Vanwinkle Mrs. Gloria B. Meyer Mr. and Mrs. John E. Manzione Mr. James J. May Ms. Terry L. McCutcheon Mr. and Mrs. W. D. McMoran Ms. Marjorie Jean Meyer and Mr. Allan B. Ms. Hsin-Chih Mao Estate of Patricia A. May Mrs. Sharon L. McCutchin Mr. Donald A. McMullen, Jr. Korsakov Mr. and Mrs. James J. Maran Mr. and Mrs. Robert A. May Mr. and Mrs. Thomas R. McDade Mr. and Mrs. William McNabb Su-Su and Jerry M. Meyer Employees of Marathon Oil Ms. Susan S. May and Mr. Andrew J. Estate of John C. McDaniels Mr. and Mrs. Cary McNair Mr. and Mrs. Howard M. Meyers Marathon Oil Corporation Owczarek Mr. Pat McDavid Mr. and Mrs. Robert C. McNair Mr. Stuart I. Meyers Mr. and Mrs. Jerry E. Marbut Bob Mayberry Foundation Dr. Alison McDermott and Dr. Adrian Glasser The Robert and Janice McNair Foundation Stuart I. Meyers Family Foundation Dr. Steven J. Marcello Dr. Dan Maydan John and Patricia McDonald Mr. and Mrs. Corbin A. McNeill, Jr. Mr. and Mrs. Al M. Micallef March of Dimes Foundation The Jill & Clarence Mayer Family Ms. Mary A. McDonald McNeill Charitable Foundation Michael Rudelson and Company Ms. Nancy W. Marcus Mrs. Nancy J. Mayers Fain McDougal Corbin and Dorice McNeill Foundation Mr. and Mrs. Edward G. Michaels III Mr. Steve J. Marcus Mr. and Mrs. Kenneth R. Mayfield Mr. and Mrs. Fred S. McDuffie Estate of Laura Friedeck McNemar Mr. and Mrs. Harvey Michaels Mr. Edward Mardigian, Jr. Ms. Easter A. Maynard and Mr. John Parker Mr. and Mrs. James McElvany Mr. and Mrs. Terry McPhail Mr. and Mrs. Mark D. Michaud Mardigian Foundation Mr. and Mrs. James H. Maynard Mr. and Mrs. M. Kevin McEvoy Mr. and Mrs. Michael R. McQueen The Michelle-Adele Foundation Ms. Frances Marek Mrs. Jessica Maynard and Mr. William Quinton Mr. and Mrs. Lance C. McFaddin Mr. and Mrs. Charles D. McVean Ms. Abigail J. Michelson and Mr. Roy S. Mr. and Mrs. Joe A. Marek Maynard McFadin Foundation McVean Trading & Investments, LLC Thomas III Mr. and Mrs. R. Stan Marek, Jr. Maynard Family Foundation Thomas W. and Patricia A. McGarity Dr. and Mrs. Gilbert R. Meadows Mr. and Mrs. George Michulka Mr. Ralph S. Marek Mr. and Mrs. Gary R. Maynor Mr. and Mrs. Mike McGee Mr. Henry E. Meadows, Jr. Micro Metals Incorporated Marek Family Foundation Mr. Ted Mayo Suzanne and Patrick McGee Ms. Lynn Meagher Microsoft Giving Campaign Ms. Violet R. Margly Peggy and Lowry Mays Mr. and Mrs. Terrell McGee Jason and Laura Meaux Mr. John Gregg Middleton Mr. and Mrs. Rodney H. Margolis Mays Family Foundation Ms. Virginia A. McGee Med Fam Benefits Private Foundation Frank H. and Elrose Migl Mrs. Ellen Marino Mazda North American, Inc. Mr. and Mrs. Terry McGill Mediaison Texas LLC Ramon F. and Stephanie A. Miguez Mrs. Teresa P. Markle Ms. Susan E. Mazer Dr. and Mrs. James W. McGinity Mr. James G. Medill Mr. and Mrs. Marvin J. Migura Mrs. Leigh Marks Mr. David R. McAtee II Louise and Denzil McGlashan Mr. and Mrs. Frank Medina IV The Mike Doiron Legends of Friendswood Golf Tournament Mr. Steve M. Marks Mr. and Mrs. Clifton H. McCall John P. McGovern Foundation Stacy and Mike Medrano Mr. Raymond Mikolajczyk Ms. Ann Marmion Mrs. Dolores L. McCall Mr. Edward McGowan The Medrano Family Foundation Mr. and Mrs. Stephen W. Miles Mrs. Janey B. Marmion Dr. Sandra A. McCalla Ms. Amy McGrath Medtronic, Inc. Mr. and Mrs. Marty McCambridge Stephen Warren Miles and Marilyn Ross Miles Ms. Mary Sue Marmion Mr. Jim McGrath Mr. and Mrs. Edward M. Medvene Foundation Mr. Eugene O. Marquette Mr. and Mrs. David McCann Mr. and Mrs. Timothy M. McGrath Ms. Linda Meek Mr. and Mrs. Kelly F. McCann, Sr. Mr. and Mrs. Andy Miller Mrs. Jo Marsh Mr. Kyle A. McGraw Mrs. Nancy C. Meek Mr. and Mrs. Barry R. Miller Mr. and Mrs. Tom F. Marsh Ms. Tanya J. McCann Mr. and Mrs. Jack McGuire Mrs. Sue E. Meek Mr. and Mrs. David McCarthy Catherine and Hugh Miller Tom and Charlene Marsh Family Foundation Estate of John A. McGuire The Meek Foundation Mr. Cecil Miller Mrs. Marie M. Marshall McCarthy Building Companies, Inc. McGuire Family Foundation Dr. Elke B. Meier and Dr. William B. Gail McCarthy ROW Partners, LLC Mr. and Mrs. David L. Miller Mr. and Mrs. Robert H. Marshall Brenda and Joe McHugh Nancy and Peter Meinig Mr. and Mrs. Dennis C. Miller Marshall’s Service Center Mr. and Mrs. James W. McCartney Mr. and Mrs. Edmund McIlhenny The Meinig Family Foundation The Catherine Terrell McCartney Foundation Ms. Doris E. Miller and Mr. Donald R. Mr. and Mrs. Ralph S. Marston McIlhenny Company Estate of Caroline V. Meirs Fitzgibbons Mr. and Mrs. Charles E. McCarty T. J. Martell Foundation Mr. and Mrs. Bruce McIninch Mr. and Mrs. James Meischen Mr. and Mrs. Jack E. Miller Mr. Matthew McCauley Mr. and Mrs. Charles D. Martin Mr. and Mrs. Cal McIntosh Mr. Mario Melancon Mary Catherine Farrington Miller Ms. Diana McClaferty Ms. Janet A. Martin Mr. William A. McIntosh Melanoma Research Alliance Mrs. Patricia J. Miller Mr. and Mrs. Matt McClain Mr. and Mrs. Joe R. Martin, Jr. McIntosh Foundation, Inc. Mr. and Mrs. David Melass Mrs. Rhea J. Miller Captain Robert P. McClanahan, Jr. Estate of Josephine Williams Martin Ms. Janet M. McIntyre Larry and Nancy Mellenbruch Mr. and Mrs. Richard L. Miller Ms. Mary G. McClean The Charles D. and Twyla R. Martin Foundation Shirley & William McIntyre Foundation Mr. and Mrs. James Melloan, Jr. Mr. Ronald Miller Mr. and Mrs. Ron McClellan Martin Preferred Foods Mr. and Mrs. Sidney Barksdale McKay Ms. Betty B. Melnik Mr. and Mrs. Scott Michael Miller Mr. and Mrs. Scott McClelland Mr. and Mrs. Carlos A. Martinez Mrs. Eileen McKean Mr. and Mrs. Joseph J. Melnyk Mrs. Shirley B. Miller Mr. and Mrs. Sam W. McClendon Mr. Oscar Martinez Mr. and Mrs. Jerome S. McKee Mr. and Mrs. Lawrence J. Melody Dr. and Mrs. Stephen Miller Mr. Galen McCloskey Ms. Patricia Martinez Mr. and Mrs. Philip R. McKee Mr. Henry H. Melton, Jr. Mr. and Mrs. Steve Miller Mr. and Mrs. Ray McCloskey Mr. and Mrs. Robert F. Martinovich Rob and Ann McKee Family Foundation Mr. and Mrs. Mike H. Meltzer The William D. Miller Family in honor of Kristina Mr. and Mrs. David Marye The Honorable and Mrs. Austin McCloud McKee Family Foundation Inc. Dr. and Mrs. John Mendelsohn Eckman Flora Mason Mr. Mark McCloy Mr. and Mrs. David S. McKeehan Mercedes Benz of The Woodlands Arnold and Suzanne Miller Charitable Fund John B. and Doris Casey Mason Mr. and Mrs. Curt McClymond J. Steven and Carol Porter McKenzie Mercedes T. Bass Charitable Corporation The David B. Miller Family Foundation Masraff’s Mr. and Mrs. Brian T. McCole Mr. and Mrs. Timothy M. McKeon Mr. Clyde Merchant C. Wayne & Patricia J. Miller Foundation Mr. and Mrs. Michael J. Massie Judy and Bill McColgan Mr. Martin McKerrow Ms. Gail Merel and Mr. Christopher E. Dack Steven and Sheila Miller Foundation Mr. and Mrs. Andrew Massimilla Mr. Craig and Mrs. Sharon McCollam Mr. and Mrs. William L. McKinney Mr. William D. Meriwether, Jr. Ms. Wendy Millhouse Mr. and Mrs. Henry J. Massman IV Mr. and Mrs. James R. McComas Mr. Doug McKinnon Merlin Development LTD CO Mr. and Mrs. Frank Milton, Jr. Massman Construction Company Red and Charline McCombs Ms. Jean T. McKnight Mrs. Helen J. Merrill Mrs. Claire Mindock Mr. and Mrs. Eric E. Masterson The Red and Charline McCombs Family McLane Company, Inc. Captain and Mrs. Hugh A. Merrill Mr. and Mrs. David Minton Foundation Masterword Services, Inc. Drayton and Elizabeth McLane Foundation Mr. Jeff Merritt Mirador Group The Walter and Nancy McConnell Designated Mr. Charles E. Mathis Fund of The Community Foundation of Dr. Darlene W. McLaughlin and Mr. James Colonel and Mrs. Robert A. Mesick Ms. Paula Mischer Mrs. Cheryl M. Mathis Western North Carolina McLaughlin, Jr. Dr. and Mrs. Joseph F. Messenbaugh III Mischer Investments, L.P. Mr. and Mrs. William C. Mattei, Sr. Kathy and Jim McCool Ms. Laure C. McLaughlin Ms. Peggy S. Metcalf Ms. Rhonda Mishler Mr. and Mrs. Kade L. Matthews Cathy and Ron McCormick Mr. and Mrs. Bart A. McLean MetLife Foundation Ms. Cheryl Mitchell Karen and Charles Matthews Ms. Janet A. McCormick Mr. and Mrs. Bruce W. McLean Mr. and Mrs. Harold Metts Mrs. John Mitchell

57 MD Anderson Annual Report

Mr. Morris Mitchell Mr. and Mrs. Huey Morris Ms. Martha W. Murphy and Mr. John W. Mr. and Mrs. Thomas B. Nenninger Mr. and Mrs. Wade T. Nowlin, Jr. Mr. and Mrs. Leonard F. Mitschke Mr. and Mrs. Matthew Morris “Jack” Leahy, Jr. Mr. and Mrs. Daniel Nerbonne Mr. and Mrs. Wade T. Nowlin, Sr. Mr. and Mrs. David A. Mitteis Mr. Paul L. Morris Mr. and Mrs. Richard J. Murphy Nerenberg Foundation Mrs. Susan M. Noyes Mr. and Mrs. Ronald Mittelstaedt Mr. and Mrs. Thomas C. Morris, III Murphy Oil Corporation Joseph and Debra Neskora NRG Oncology Foundation, Inc. Mr. Neal Miura Dr. and Mrs. W. T. Morris, Jr. Mr. James D. Murray Mr. and Mrs. Joseph H. Netherland, Jr. NuStar Logistics, L.P. Mr. and Mrs. Sam Mizrahi Morris/McCarthy Mr. and Mrs. Michael W. Murray Mr. and Mrs. Tom Netting Mr. and Mrs. Thomas B. Nusz Mobil Foundation, Inc. Ms. Carla B. Morrison Mrs. Sally C. Murray Mr. and Mrs. Lee F. Nettles Mr. and Mrs. Freddie A. Nutt Mobil Steel International, Inc. Mr. and Mrs. Chet W. Morrison Mr. Stephen B. Murray NEU Foundation of California Mr. Mark Nyquist Modern Machine Shop, Inc. Mr. and Mrs. David G. Morrison III Murray Law Firm The Neubauer Family Foundation Modestus Bauer Foundation Ms. Kellie Jean Morrison Mr. Tony Muscarello Mr. and Mrs. Toby R. Neugebauer Carlton and Nancy Moffett Mr. Tom A. Morrison IV Mr. and Mrs. Jeff Musgrove Mr. and Mrs. Joseph R. Neuhaus, Jr. O Ms. Louise H. Moffett Morrison and Morrison, Inc. Mr. and Mrs. Henry G. Musselman Mr. and Mrs. Donald R. Neumeyer Mr. and Mrs. William D. Oates Mr. and Mrs. Roger Mogonye Ms. Penny Morriss Mr. Elmer T. Musshorn Mr. and Mrs. Carl W. Neun The Marilyn and Sonny Oates Foundation Dr. and Mrs. Radhe Mohan Mr. Lyle Morrow Mr. and Mrs. Gray H. Muzzy Neuroendocrine Tumor Research Foundation Mrs. Carolyn C. Oatman Mr. and Mrs. Jerry A. Mohn Mr. and Mrs. David S. Morse Mr. Donald C. Myers Neustadt Charitable Foundation Mr. Howard F. Oberg Mr. and Mrs. Randolph M. Moity, Sr. Jeff and Jana Morton Dr. Georgia Myers and Mr. S. C. Myers The New York Community Trust Mr. and Mrs. Bill O’Brien Mr. and Mrs. John N. Molbeck, Jr. Morton Family Foundation Mr. and Mrs. Jeremy B. Myers New York Life Foundation Ms. Megan O’Brien Molex, LLC Mr. and Mrs. Charles D. Moseley, Jr. Mrs. Maxine Myers Mr. Gary A. Newberry Obie O’Brien Shelah and Marc S. Moller Paula and Jon Mosle Mr. and Mrs. Mike A. Myers Mr. and Mrs. Robert Newberry Mr. Patrick O’Brien Mr. and Mrs. Thomas D. Molzahn, Sr. Bill and Janis Mosley Arthur B. & Marion V. Myers Trust Fund Mr. and Mrs. David Newell Mr. and Mrs. T. B. O’Brien Mr. Joseph S. Monaghan, Jr. Dr. Mark Mosley and Mrs. Kristan Mosley Myriad Genetics, Inc. Mr. and Mrs. John A. Newkirk Mr. Thomas B. O’Brien Mr. and Mrs. Charles B. Moncrief Mr. Lewis Moss Mr. Gary G. Newman Occidental Petroleum Corporation Mrs. Nancy E. Moncrief Mr. and Mrs. William P. Moss Mr. and Mrs. Raleigh Newman N Occidental Petroleum Corporation Matching Mr. Gary Monie Ms. Amy Mosser Mr. Keith O. Newton Oceaneering International, Inc. Mr. and Mrs. Thomas A. Monson Mr. Wiley L. Mossy Employees of NextEra Energy Nabors Corporate Services, Inc. Ms. Virginia O’Connell Monster Energy Company The Jane P. and Wiley L. Mossy Jr. Foundation The Ney Foundation Nabors Industries Ltd. Dr. Brendan D. O’Connor Mrs. Denise D. Monteleone Mr. Ben Motion Ms. Amy T. Ng Ms. Sandy Nachman Mr. Jerald A. O’Connor Mr. and Mrs. Terry R. Montesi Ms. Kimberly Mount Ms. Anne Nghiem Naegeli Transportation, Inc. Mrs. Lorraine Odasso Mr. and Mrs. Ben C. Montgomery Mountain Area Health Education Center, Inc. Mr. Paul Niccum Ms. Flolyn Naegelin Mrs. Charles Oden Mr. Jimmy B. Montgomery Mr. Wayne W. Moureau Mr. Joe M. Nichols, Sr. Mr. and Mrs. Firozali M. Nagji Mr. Jerry L. Oden Mrs. Mary C. Montgomery Beverly and Jerry Mouser Mr. Randy Nicholson Dr. Roy Y. Nakamoto The Sydnor and Olga Oden Foundation Mr. and Mrs. William C. Montgomery Mr. Robert W. Mouton The Stiles Nicholson Foundation Ms. Fatima Naqvi Mr. and Mrs. Clayton Odom Montgomery Family Foundation Inc. Mr. Jim Moylan, Sr. Mr. and Mrs. Michael R. Nicolais Mr. Govind Narasimhan Mrs. Mary C. Odum Montgomery Trucking Co., LLC Mr. and Mrs. Robert C. Mueller Mr. and Mrs. Jerome A. Nicolas Mr. and Mrs. Albert Narath The OFIS - Office Furniture Interior Solutions Ms. Patricia O. Monti Mr. and Mrs. Steven L. Mueller Mr. and Mrs. Ronald E. Nilson Mr. and Mrs. Peter Nardo Mr. and Mrs. John H. Ogden Mr. Cecilio Montoya Mr. and Mrs. Steve Mukavitz Mrs. Patricia Nishihata National Beverage Corp. Mr. and Mrs. Charles M. Oglesby Monument Investments, Inc. Lisa and Greg Mullen Ms. Kay Nix National Brain Tumor Society Mr. and Mrs. James E. Oglesby Jeff and Sandy Monzingo Mr. and Mrs. Timothy T. Mullen Nix Forest Industries, Inc. National Breast Cancer Foundation, Inc. Ms. Maureen A. O’Gorman Cory Monzingo Foundation Mr. Michael I. Muller Mr. and Mrs. Dennis E. Nixon National Christian Foundation Houston Beverly and Will O’Hara Mr. Frank S. Mooney Muller Honda Noah’s Light Foundation National Foundation for Cancer Research Mr. and Mrs. Robert Ohmes Mr. Arthur J. Moore Mr. Terence Mullervy Kathy and Bill Noble National Marrow Donor Program Mr. David E. Ohre Mrs. Betty Moore Ms. Suzanne Mulligan Noble Corporation plc National Pancreas Foundation Mrs. Patricia S. O’Kieffe Mr. and Mrs. Christopher M. Moore Mr. and Mrs. Don R. Mullins Noble Tile Supply, Inc. National Philanthropic Trust Dudley and Judy Oldham Mrs. Marie O. Moore Mr. and Mrs. Joe C. Mullis, Jr. Mr. and Mrs. James W. Nobles, Jr. National Science Foundation Mark and Lynette Oldham Mr. Terry Moore Mr. and Mrs. David G. Mulock Mr. William Noe Mr. and Mrs. John L. Nau III Mr. and Mrs. Dan J. O’Leary Mr. and Mrs. Lewis J. Moorman III Multiple Myeloma Research Foundation Mr. and Mrs. William D. Noel Mr. Billy Navarre Mr. and Mrs. Alex H. Oliver Mr. and Mrs. Marvin C. Moos Miriam and Jim Mulva Mr. Jon Noeth Mrs. Carrie Navarre Mr. and Mrs. David E. Oliver Mr. and Mrs. John A. Moran Susan and Pat Mulvey Mr. and Mrs. Jimmy W. Nokes Mr. and Mrs. Louis K. Navias Mr. and Mrs. David M. Oliver, Jr. Mr. Patrick J. Moran Mr. and Mrs. William T. Mumford Mr. David P. Nolan Navias Family Foundation Mrs. Mary Ann Olivier Mr. and Mrs. Sidney S. Moran Ms. Betty J. Munnell Mr. and Mrs. Steve M. Nolan Mr. Tom Nawa Mr. Homer Olsen, Jr. Mr. and Mrs. William M. Moran Mr. Henry Munoz Mrs. Vickie T. Nolen Ms. Mary Naylor Mr. and Mrs. Rudolph K. Olson P. J. Moran Foundation Mr. Bill Munro Mr. Adil O. Noorani Nazrid Inc. Mrs. Mary Olszewski Janet Mordecai Munro’s Dry Cleaning Company Mr. and Mrs. Karim K. Noorani Mr. Jim Neal Once Upon A Time... Mr. David M. Moreau Mr. and Mrs. Kenneth A. Munson Mr. and Mrs. Richard Noppe Mr. and Mrs. Richard Neal Mrs. Helen P. Oncken Mr. and Mrs. Roland L. Moreau Mr. and Mrs. Nick Munson Mr. Andres S. Noriega, Jr. Mr. and Mrs. Edward J. Neckar Oncoceutics, Inc. Mrs. Diana T. Morehouse Mr. and Mrs. George W. Murfee Mr. and Mrs. Carlos Noriega Dr. and Mrs. Warren F. Neely Oncomatryx Biopharma, S.L. Ms. Emily H. Moreland Murfee Engineering Company, Inc. Mrs. Esther R. Norris Dr. Shanti and Sirisha Neerukonda Mr. and Mrs. Don R. O’Neal Moretti Golf, LLC Mrs. Louise T. Murfey Mr. and Mrs. Timothy J. Norris Mr. and Mrs. James P. Neeves Mr. and Mrs. John A. O’Neal, Jr. Bill and Sara Morgan Murfey Foundation Dellora A. and Lester J. Norris Foundation Mr. and Mrs. Dru A. Neikirk Mrs. Patty Cerf O’Neil Mr. and Mrs. Doug Morgan Mr. George Murickan North American NeuroEndocrine Tumor Society Mrs. Laura B. Neill The Frank O’Neil Family Foundation Morgan Stanley Charitable Spending Account Ms. Reba Murphey North Carolina Community Foundation Inc. Mr. Corliss J. Nelson Mr. and Mrs. Harvey E. O’Neill Morgan Stanley Corporation Ms. Christine L. Murphy Northern Trust Mr. and Mrs. Donald Nelson Steven and Rose O’Neill Morgan Stanley Global Impact Funding Trust, Mr. David Murphy Carl Norton in memory of Shouling Liu Norton Mr. and Mrs. John C. Nelson ONEOK Inc. Ms. Erica M. Murphy Mr. and Mrs. Michael W. Norton Kathryn and Ted Nelson Kay M. Onstead Ms. Joan Morgenstern Ms. Kashetta Murphy Norton Rose Fulbright Mr. Lance Nelson Robert R. and Kay M. Onstead Foundation Mr. Dwight Morley Mr. Larry Murphy Mrs. Joan A. Noto Dr. and Mrs. Ronnie E. Nelson Ms. Frances C. Oppenheimer Mrs. Christine Morris Dr. M. John Murphy Novel Anti-Infective Technologies LLC

58 PARTNERS IN MAKING CANCER HISTORY

Estate of Mildred M. Oppenheimer Mr. Patrick Park Mr. Lee D. Pennington Monroe Dunaway Anderson Society Orange County Building Materials, Inc. Rosey and Ray Park Mr. and Mrs. Timothy M. Pennington Orange County Community Foundation Mr. Arthur Parker Pamela J. and James D. Penny Mrs. Franca G. Oreffice Dr. and Mrs. David Lyle Parker PepsiCo Foundation New members, Sept. 1, 2015 - Aug. 31, 2016 Mr. and Mrs. Paul F. Oreffice Mr. and Mrs. Jerre L. Parker Mr. Daniel Pequeno The Oreffice Foundation Maggie Ryden Parker Mr. and Mrs. Steven D. Percifield Established in 1995, the Monroe Dunaway Anderson Society Mr. and Mrs. Akinori Orimo Ms. Mary E. Parker Mr. Troy B. Percival recognizes individuals and families who have selected the Mr. and Mrs. Sanford H. Orkin Mr. and Mrs. Mike Parker The Percy Fund programs at MD Anderson to benefit from a planned gift such Barbara and Sanford H. Orkin Foundation, Inc. Mr. and Mrs. Phillip M. Parker Mrs. Janice M. Peregoy as a bequest, life insurance policy or other similar vehicle. Listed David A. and Cathy R. Orlando Mrs. Robert A. Parker Mr. Manuel A. Perez Orr Family Foundation Ms. Sharon Parker Perio Health Professionals, PLLCC here are new members of the society who recently named the Mrs. Althea Evelyn Osborn The Parker Foundation Colonel and Mrs. Peter L. Perkins institution in their estate plans. Osborn Surrey Enterprises Ltd Parker Highlander PLLC Mr. and Mrs. Richard Perkins Mr. and Mrs. Dee S. Osborne Parker’s Building Supply Mr. Steve Perkins Mr. Alvin F. Adams Mr. Val L. Lofgren Mr. and Mrs. Guy J. Ossello Mr. James T. Parkinson III Permian Basin Area Foundation Ms. Kimberly M. Alfonso Mr. John E. Manzione Mr. Ronald Osterberger Mr. and Mrs. Donald W. Parks Mr. Frederick A. Perrenot Mr. Tom J. Oswalt The John C. and Carolyn Noonan Parmer Mr. and Mrs. Joe L. Perrin Mr. M. Stephen Beard Mr. Robert J. Mathews Ms. Martha Farish Oti Private Foundation Mr. Leo F. Perron, Jr. The Otis Booth Foundation Mr. Allen Parnell Mr. Sam R. Perry Mr. Ray J. Belsley Ms. Janice C May Mr. and Mrs. Maury Otterstetter Mr. Jerry Parrish Estate of Celina R. Peterle Mr. Richard Bennett Mrs. Nancy J Mayers Mrs. Jeanne Oudenhoven Mr. and Mrs. Ronald L. Parrish Mr. and Mrs. Charles P. Peterman Mr. and Mrs. John F. Oudt Mr. and Mrs. Mike Parsons Judge and Mrs. Jimmie C. Peters Mr. Hugh C. Berry, Jr. Mrs. Laura McNemar Ms. Carol E. Oukrop Morton and Susan Parsons Mrs. Lee Ann Peters Mr. Aleck C. Bond Mr. Kenneth K. Mercer Out Source Machine Co. Mr. and Mrs. Charles A. Partain Mr. and Mrs. BJ Petersen Ovarcome Non-Profit Inc. Partners Healthcare System Dr. Judith A. Peterson and Dr. Donald N. Mr. Frank J. Bonitati Mr. Carlton Moffett Ovarian Cancer Research Fund, Inc. Gary and Barbara Pasquinelli Peterson Mr. Bruce A. Broadbent Ms. Joan Morgenstern Mr. and Mrs. Marvin N. Overstreet Patco Machine & Fab. Inc. The Peterson Foundation Mrs. Anne Dale Owen Mrs. Patrick J. Patek Mr. Alfred J. Petit-Clair, Jr. Ms. Ena Burlingame Ms. Rosa Pennick Petroleum Solutions, Inc. Mr. Kenneth A. Owen Dr. Daksha M. Patel Ms. Hutis O. Carlson Ms. Joyce L. Phillips Mr. Thomas E. Owen Mr. and Mrs. Malcolm Paterson Mrs. Shirley Petrosky Dian Graves Owen Foundation The Patient-Centered Outcomes Research Ms. Diana Petross Mrs. Candy Castle Ms. Linda L. Pirtle Institute Mr. and Mrs. Roald Pettersen Mrs. Cindy G. Owens Mr. Irwin M. Cohen Mrs. Kathy D. Plaeger Mr. and Mrs. Wilton L. Owens Mr. and Mrs. Howard J. Patin Caroline Pettit and R. Richardson Pettit Nancy Owens Memorial Foundation Patten Law Firm PC June Pettus Mr. Donald P. Dampf Mrs. Gretchen Pressburg Katie and Patrick Oxford Mr. and Mrs. Charles D. Patterson Mr. and Mrs. Scott Petty, Jr. John and Nora Patterson Petty Group, LLP Ms. Mary Victoria Damsgaard Ms. Paralee Price Mr. and Mrs. Robert L. Patton, Jr. Mr. and Mrs. Elliott Pew, Jr. Mrs. Clemence Alice Deane Major General Jack W. Ramsaur II P Mr. Suhas P. Patwardhan Mr. and Mrs. Carl Pfeiffer Ms. Janelle M. Pauer and Mr. Andrew E. David and Kelly Pfeil Mr. Hall J Debusk Ms. Mary F. Rich P & L Cast Stone Inc. Shirley Pfizer Foundation, Inc. Mr. Raymond H. Eaves Mr. William J. Roberson, Jr. Mr. and Mrs. Gary H. Pace Dr. and Mrs. James A. Paulson Pfizer Inc. Mr. and Mrs. J. C. Pace III Paulson Family Foundation Ms. Marjorie L. Pflaum Myra Eilenberg Trust Ms. Martha Rolingson Mr. and Mrs. Wayne H. Pace Mr. and Mrs. Henry B. Paup PGA TOUR Mr. Donald F. Fisher Mr. Donald Cameron Ross The Pace Fund, Fort Worth Ms. Arlene Payne PGA Tour Wives Association Dr. Jerrold M. Pachman In Memory of Diane PDI Mr. Ha Q. Pham Mrs. Helen H. Fourmy Mr. Andrew E. Sabin Pachman Mr. and Mrs. Arthur W. Peabody, Jr. Mr. and Mrs. Robert E. Phaneuf Pacira Pharmaceuticals, Inc. Mrs. Marguarette Frederick Mr. Michael J. Schimberg Peach Outreach Mr. and Mrs. Bill Phelps Mr. Andrew K. Packard Mr. Guy P. Peacock Mr. and Mrs. Dionne S. Phelps Mr. William A. Frumovitz Ms. Lucy L. Sharp Mr. and Mrs. Carter F. Page Mr. Paul A. Peacock Mr. and Mrs. Elliott W. Phillips Ms. Despina Page The Honorable Bruce S. Gelb Marvin Silverman Trust Ms. Nola Pearman Mr. Harry H. Phillips James and Linda Painter Mr. Clint H. Pearson Mr. Jack D. Phillips Mr. Robert M. Hanley Sheila Silverman Trust Mr. James Pajakowski Mr. and Mrs. Lee Roy Pearson III Mrs. Jennie L. Phillips Palafox Hospitality, LTD Mr. B. Paul Hirsch Harry J. Skefos Pecan Deluxe Candy Company Mr. John S. Phillips Palermo Properties, LLC. Mr. and Mrs. Patrick A. Peck Phillips 66 Mr. and Mrs. Bruce Palfreyman Mr. Randall Howard Mr. Allen L. Smith Mrs. Rodman S. Peddie The Waite and Genevieve Phillips Foundation Mr. Max Palisson Peerless Events And Tents Mr. Ross Philo Mrs. Adeline D. Hudson Mr. Terry Speed Mr. and Mrs. C. Robert Palmer Mr. and Mrs. Roger Peery Mr. Paolo Piacentini Stuart and Caroline Palmer Mr. Herbert L. Ingram Mrs. Lily Stark Mrs. Kimmie C. Peet Mr. and Mrs. James M. Piccione Palmer Foundation Mr. and Mrs. Harry N. Pefanis Mr. Steven Pickel Mr. Jerry Irwin Ms. Mickey Stern Palmetto Partners, Ltd. Mr. David T. Peirce Beverly and Robert S. Pickelner Mr. and Mrs. Terry Pannell Dr. Marilyn E. Johnson Dr. Robert S. Toth Mr. and Mrs. Robert A. Peiser Mary Martha and John Pickens Anastasia and Nicholas Papadakes Mr. Owen H. Pelham, Sr. Mr. and Mrs. Robert H. Pickens Ms. Mary B. Kite Mrs. Vernita J. Turpin Ms. Natalie I. Papadam Richard and Kaye Pendleton Mr. T. Boone Pickens Vicky and Harris Pappas Ms. Lucy Lane Ms. Lori D. Valencic Penland Foundation Mr. and Mrs. William C. Pickens Pappas Restaurants, Inc. Mr. and Mrs. Donor D. Penn Mr. and Mrs. W. E. Pielop III Mr. Bruce E. Latimer Mr. Jerry M. Waldschmidt Mr. and Mrs. Daniel K. Park Pennies in Action Foundation - Susan G. Mr. and Mrs. W. Bernard Pieper Mr. and Mrs. Kelly Park Atkinson Fund Mr. Charles Lemoine Ms. Doris E. Zagon Mr. and Mrs. Edward K. Pier

59 MD Anderson Annual Report

Mr. and Mrs. Henry F. Pierce Preng & Associates Major General and Mrs. Jack W. Ramsaur II Renaissance Charitable Foundation, Inc. Mr. and Mrs. Edward E. Robbs Mr. and Mrs. Robert R. Pierce Mrs. Sheila Prenowitz Mr. and Mrs. Gary M. Ramsey Mr. and Mrs. John W. Renfro Mr. William J. Roberson, Jr. Pin Down Bladder Cancer Inc. Mr. and Mrs. Norman G. Preskitt Ms. Kim E. Ramsey Renfro Foods, Inc. Don and Jennifer Robert Mr. and Mrs. Sheldon Pinchuk Mrs. Gretchen Pressburg Mr. Ray D. Ramsey Mrs. Renfro’s Salsas Ms. Barbara H. Roberts Pinion Family Foundation Prevent Cancer Foundation Rancho Viejo Cattle Co., Ltd. The Research Foundation for State University Mr. and Mrs. Braxton L. Roberts, Jr. Pink Peonies Foundation The Honorable and Mrs. John Price Fairfax and Risher Randall of New York Mrs. Carrie A. Roberts The Pink Ribbon Shop Mrs. Marcia J. Price Mr. and Mrs. Jack P. Randall Retina Research Foundation Ms. Dorothy N. Roberts Pink Ribbons Project John and Marcia Price Family Foundation Roberta K. Randall Charitable Foundation Miss Nancie L. Rettig Mr. Grady W. Roberts Ms. Patti Pinkston Price Gregory International, Inc. Jack & Beverly Randall Foundation, Inc. Ms. Connie Reum and Heather’s Heroes Mr. and Mrs. Jerry O. Roberts Pioneer Natural Resources USA, Inc. PricewaterhouseCoopers Foundation Mr. and Mrs. Robert L. Randolph The Reutzel Foundation Mr. Richard H. Roberts Mr. and Mrs. Gregory P. Pipkin Mr. and Mrs. Rod Prichard Randy Lyne Preferred Pump Rexanna’s Foundation for Fighting Lung Cancer Ms. Sheryl L. Roberts Mr. and Mrs. Bob Pitcock Ms. Lori F. Priess Mr. and Mrs. Salvatore A. Ranieri Mr. and Mrs. Charles T. Reynolds Mr. and Mrs. Thomas C. Roberts Mr. and Mrs. Robert Pitcock Primrose School of Coppell Ms. Ashley Scott Rankin Mr. and Mrs. Ted Reynolds Robert’s China Crystal & Sliver, Inc. Mr. and Mrs. William Pitts Prostate Cancer Foundation Mr. Paul Ranon Mr. and Mrs. Reynaldo Reza The Aileen K. and Brian L. Roberts Foundation Mr. and Mrs. Frederick J. Plaeger II Mr. and Mrs. Bill Prout Mr. and Mrs. Karl A. Ransleben Mr. Phillip Rhee Trish Roberts-Miller and Mr. Jim Roberts-Miller Dr. Carl Plager Mr. Tony Puleo Mr. Gilbert J. Ransonet The Rheumatology Research Foundation Mr. and Mrs. Corbin J. Robertson, Jr. Plains All American Pipeline Mr. Tadd Pullin Leon W. B. Rasberry M.D. Mrs. Charlene Rhodes F. D. Robertson PlainsCapital Bank Dr. Katherine Pulse and Mr. Dewey A. Ms. Connie B. Rasor Mr. Thomas L. Rhodes, Jr. Mr. and Mrs. Jack Y. Robertson Mr. and Mrs. Roger B. Plank Stringer III Steven and Maureen Rathgaber Mr. and Mrs. Gary G. Rich Jack Robertson and Joanne Havner Plano Land Trust Corporation Puppy Up Foundation Carolyn and Karl Rathjen, M.D. Ms. Mary F. Rich Mr. Julian H. Robertson, Jr. Mrs. Madeline C. Plansky Mrs. Fredna E. Purkey Mr. and Mrs. Robert D. Rathmell Martin D. and Barbara H. Rich Family Ms. Lillie T. Robertson Mr. James Platt Dr. Roger Purser Rathmell Family Foundation Charitable Foundation Robertson Foundation Mr. and Mrs. Steven W. Platt Mr. J. R. Purvis Ms. Frances E. Ratliff Mr. and Mrs. Michael A. Richard Mr. and Mrs. Bruce A. Robin Pledgeling Foundation Mr. and Mrs. Kyle Purvis Mr. and Mrs. Lyle J. Ratner Ms. Darla J. Richards Ms. Nancy G. Robinett and Mr. John J. Hamlin Mr. and Mrs. Edward A. Plummer Putting for Prostates Mrs. Gail Williamson Rawl Mrs. Diane Richards and Dr. George Revtyak Dr. Chester D. Robinson Mr. and Mrs. Poe Ms. Marilou E. Pych Mr. and Mrs. Charles D. Ray Mr. and Mrs. Frank H. Richardson Chris and Jennifer Robinson Dr. and Mrs. David F. Pohl Mr. and Mrs. Donald Ray Ms. Lou Ann Richardson Mrs. Edgar A. Robinson Mr. and Mrs. Martin T. Richardson Colonel and Mrs. Robert C. Poland Q Mrs. Vera L. Ray Mr. George A. Robinson IV Mr. David G. Polis Raydon, Inc. Mr. and Mrs. Richie Richardson Mrs. Harriett J. Robinson Mr. and Mrs. Joe Polk Bessie L. Rayford Foundation Mr. and Mrs. Robert B. Richardson Mr. Joseph E. Robinson Qatar Foundation Ms. Stephanie Richardson Mrs. Janet E. Pollock Quagga Accessories, LLC Mr. and Mrs. Martin S. Raymond Mr. and Mrs. Michael J. Robinson Mr. and Mrs. David Pollok Ms. Kim Raynor Frank and Marilyn Richardson Family Nancy and Oscar Robinson Quality Assurance Roofing Foundation Mr. and Mrs. Ralph Ponce de Leon RB Group International Freight Forwarding, Inc. Mr. and Mrs. Steve Robinson Quality Electric Steel Castings, L.P. Dr. Ellen R. Richie and Mr. Sheldon E. Richie Ms. Lenora Pool Realan Foundation, Inc. Robinson Family Foundation Mr. and Mrs. Steven J. Quamme Gail and Gene Richter Mr. and Mrs. Otis R. Pool Mr. Jim Ream George A. Robinson IV Foundation Dr. and Mrs. Albert Quan Liz and Al Richter Mr. William D. Pool Ms. Emily Reaser The Judith Liebenthal Robinson Ovarian Cancer Quanex Foundation Mr. Donald E. Ricketts Lewis H. Pool Foundation Rebecca’s Foundation Foundation Quantum Gas & Power Services, Ltd. Mr. and Mrs. Thomas G. Ricks Jon L. Poole Red Bull North America, Inc Robinson Ranch Mr. Brendon C. Quick Mr. and Mrs. Robert Ridgley Mrs. Lois B. Pope Mr. Gerald B Redditt Mr. and Mrs. Jonathan Robson Mr. and Mrs. Mark Quick Mr. and Mrs. Sid Ridlehuber Mr. William L. Pope Mrs. Irene I. Reece Mr. and Mrs. Joel H. Robuck Ms. Eileen R. Quinn Ms. Susan M. Riedel Mr. and Mrs. Roy Popham Mr. and Mrs. Joe G. Reed Mr. Joseph Rocha Ms. Lydia Quinones Mr. and Mrs. John J. Riedmueller Mr. and Mrs. Frank P. Popoff The Reel Deel Foundation Rocha Consulting LLC Mr. and Mrs. James D. Rieker, Jr. Porsche Club of America-Peachstate Ms. Judi A. Rees Carolyn Jones Roden Mr. and Mrs. F. Kelleher Riess Region, Inc. R Mr. and Mrs. Jordan W. Reese, III Mr. Roger J. Rodriguez Ariela Rifkin – The Len-Ari Foundation Ms. Kimberly Vanbelle Porterfield Mr. and Mrs. Tim Reese Mr. and Mrs. James M. Roe Mrs. Gloria A. Riggins Mr. Lee W. Portwood, Jr. R & P Ramirez, Ltd. Mr. and Mrs. Forrest D. Reeve Mr. and Mrs. Richard K. Roeder Dr. and Mrs. Leonard M. Riggs, Jr. Mr. and Mrs. Don E. Posey The R. R. Family Foundation Ms. Elaine L. Reeves Ms. Shannon F. Roethemeyer Mr. and Mrs. H. John Riley, Jr. Andrew & Lillian A. Posey Foundation Dr. and Mrs. Issam Raad Katherine and Eric Reeves Ms. Brandee S. Rogers Mr. and Mrs. Neil E. Rinehart Mr. and Mrs. Mike Post Mr. and Mrs. Ivar Rachkind Ms. Jill Regina Mr. and Mrs. Joe M. Rogers Mr. and Mrs. Patrick J. Riordan The Post Oak School Mr. John Raden Ms. Alexis Reich Mr. and Mrs. Jordan Rogers Mr. John Rippel Dr. and Mrs. Robert J. Potter Radiological Society of North America Mr. Edward A. Reichert Pat and Glenda Rogers Rising Tide Foundation Robert J. Potter Foundation Mr. and Mrs. William Joseph Rafferty Mrs. Aleene J. Reid Regina Rogers RITA Foundation Houston Ms. Bridget Potts Susan and Alan Rafte Ms. Alison T. Reid Sandra Rogers in Loving Memory of Bobby Mr. and Mrs. William R. Ritchie Michael and Mary Kay Poulos Mr. C. E. Ragsdale Mr. and Mrs. Andrew J. Reid Rogers Mr. and Mrs. Luis F. Rivas Mr. Kyle K. Poulson Dr. Judith A. Ragsdale and Mr. Arlin Maddox Mr. and Mrs. Donald W. Reid Estate of William F. Rogers River City Chiropractic, P.A. NE Dana and Gene Powell Mr. and Mrs. W. K. Rainbolt, Jr. Mrs. James H. Reid, Jr. T. Gary and Kathleen Rogers Supporting Family River West Meeting Associates Foundation Mr. Mark S. Powell Rainbow Pizza LLC Royce H. Reid Jaime Rivero-Santos Mr. and Mrs. Rodger R. Rohde Tom and Jane Cheever Powell Mr. and Mrs. James F. Raithel Mr. and Mrs. William P. Reid Mr. and Mrs. George A. Rizzo The RoKe Foundation, Inc. The John and Jane Powers Foundation Mr. and Mrs. W. M. Ralls Reid Family Foundation RL Investments Richard and Beverly Roland Tim and Katherine Pownell Rally Foundation For Childhood Cancer Mr. Walter Reifel, Jr. Research RLB Investments Mr. and Mrs. W. Clark Roland Mr. and Mrs. Tomaso Pozzi Mr. and Mrs. Anson M. Reilly Mr. Robert L. Ralston RLC Helicopters Mr. and Mrs. Thomas J. Rolen Mr. and Mrs. Richard E. Prasek Mrs. Diane C. Reimann Mr. and Mrs. Ronald E. Rambin RNM Investments Ltd. Ms. Martha A. Rolingson Ms. Karen H. Prather Mr. and Mrs. Kenneth P. Reis Mr. Renato Ramirez Jean and John Roach Mr. and Mrs. William R. Rolingson Mr. Anthony C. Pratt Mr. Owen A. Reischman Ms. Therese S. Ramirez and Mr. George C. The Roach Foundation, Inc. Terry and Bert Romberg Mrs. Susan S. Pratt Mr. and Mrs. James J. Reiss, Jr. Billings The Honorable and Mrs. Charles S. Robb Mr. and Mrs. Joel Romines Precision Medicine Research Associates Trust Mr. and Mrs. Rick Reitz Ms. Crystal E. Ramon-Miranda Mr. Marc E. Robb Mr. and Mrs. A. Ross Rommel, Jr. Mr. and Mrs. David E. Preng reLogistics Services Dr. Michelle Ramos and Mr. Ernest L. Ramos Robbins Geller Rudman & Dowd LLP Mr. John N. Rooney

60 PARTNERS IN MAKING CANCER HISTORY

Mrs. Sybil F. Roos Ms. Melanie A. Rustenbeck Marilyn and Donald H. Schaffer Mr. Marc S. Sclafani Mr. and Mrs. Paul J. Shaughnessy Roppolo’s Pizzeria II, Inc. Rusty Dusty LLC Mr. Jerry S. Scheer Scleroderma Foundation Mr. Scott Shaver Mr. William H. Roquemore Dr. Glenn Ruthven Mr. and Mrs. Steven E. Scheer Dr. Annette Scott Beth and David Shaw Mr. and Mrs. Thomas L. Roscetti Kathryn and Patrick W. Ryan Mr. and Mrs. Rudi E. Scheidt, Jr. Mr. and Mrs. Bill Scott Mr. Donald Shaw Mr. and Mrs. Jerome R. Rose Ms. Nancy J. Ryan David and Amy Scheihagen Dr. David W. Scott Mr. and Mrs. Kelton Shaw Ms. Pamela Rose Mr. and Mrs. Joseph W. Rybarski Mr. and Mrs. Brad A. Scherer Mr. and Mrs. Dwight Scott John and Dorothy Shea Dr. Marnie Rose Foundation Mr. and Mrs. Mike Rydin Mr. and Mrs. William R. Scherer, Jr. Mr. and Mrs. Gerald L. Scott Mr. David B. Shealy Mr. Glen A. Rosenbaum Mr. James R. Ryffel Mr. and Mrs. Robert Scheuer Mr. and Mrs. James W. Scott Mr. and Mrs. Scott Shean Mrs. Gayle Rosenberg Mrs. Helen Lho Ryu Bob and Patricia Schieffer Neal and Sally Scott Ms. Karen K. Shebaro Rozanne and Billy Rosenthal J. Thomas and Susanne Schieffer Mr. Thomas D. Scott Mr. and Mrs. Charles E. Sheedy The Rosewood Corporation Mr. and Mrs. Bobbie E. Schiel The Thomas H. and Mayme P. Scott The Sheedy Foundation Bonnie and David N. Rosner S Schiel B-R-C-P-B-B-L Foundation Inc. Foundation, Inc. Mrs. Nancy H. Sheehan Mrs. Raizy Rosner Dennis and Dorothy Schiffel Scott Universal Foundation, Inc. Mr. and Mrs. Myron M. Sheinfeld Andrew Sabin Family Foundation David N. Rosner Charitable Foundation Mr. and Mrs. Herbert E. Schilling II Mr. and Mrs. Nick Scotto Shell Oil Company Mr. and Mrs. Scott Charles Saenger Mr. and Mrs. James E. Ross Estate of Michael J. Schimberg Scripps Howard Foundation Employees of Shell Oil Company Ms. Theron D. Sage Mr. James J. Ross Mr. Donald T. Schlattman Kim and Jeff Scrivener Shell Oil Company Foundation Sage Patient Advocates Mrs. JoAnn S. Ross Dr. and Mrs. Russell H. Schlattman II Mr. and Mrs. Phillip L. Scudder Mrs. Beatrice M. Shelly Sagis, PLLC Mr. William F. Ross Mr. and Mrs. Thomas A. Schleigh, Jr. Scurlock Foundation James E. Shelly Family Trust Ms. Moni S. Sagoo Mr. Robert H. Rossen Ms. Carla K. Schlemmer Mrs. Saralyn C. Sears Mr. Charles B. Shelton III Mrs. Frances M. Saladin Ms. Elizabeth Rosso Mr. and Mrs. Pierre M. Schlumberger Mr. and Mrs. William A. Sears Mr. James D. Shelton Mr. Luis Salas The Rotary Club of Houston Foundation Schlumberger Technology Corporation Ms. Sue H. Secker Mr. Robert J. Shelton Mr. and Mrs. Franklin G. Salazar Mr. and Mrs. Clarence Roth Dr. and Mrs. Walter R. Schmeal Securit Metal Products Co. Shelving Concepts Mr. Louis Saldana Mr. Jim C. Roth Ms. Susanne M. Schmelz Seegers Foundation Mr. and Mrs. Joseph J. Shemenski Salem Baptist Church Mr. and Mrs. Charley H. Rougeau Mr. Alexander Schmidt Mr. and Mrs. Elliot M. Segal Mr. Sam Shemper Mr. and Mrs. Alan J. Sales Mr. and Mrs. Don C. Rountree Ms. Leslie A. Schmidt SEI Energy, LLC Shep F. Comeaux, CPA, MBA & Associates Ms. Margaret Saliba Mr. James J. Rouse Mr. and Mrs. Paul B. Schmidt Mr. and Mrs. Philip W. Seidenberger Mr. and Mrs. Stanley O. Sher Sally K. Ride Elementary School Mr. and Mrs. Thomas M. Rouse Mr. and Mrs. Richard W. Schmidt Arnold and Janice Seidule Mr. and Mrs. Lewis M. Sherer Mr. and Mrs. Phillip Salvador Rouse Family Foundation Dru Schmitt Mr. and Mrs. Michael J. Seiler Mr. and Mrs. Donald C. Sherman Mr. and Mrs. Rodney Salvaggio Mr. Louie J. Roussel III Mr. and Mrs. Mark Schmitz Mr. Terry Seitz Mr. and Mrs. George V. Sherman, Jr. Mr. Victor E. Salvino Arch and Stella Rowan Foundation, Inc. Mr. and Mrs. Henry T. Schmueckle Mr. and Mrs. Peyton M. B. Self III Mr. and Mrs. Jeff Sherrick Mr. and Mrs. Michael S. Samis Kevin Rowe and Irene Vlitos-Rowe Mr. and Mrs. Charles W. Schneider Self Foundation Mr. and Mrs. Richard Sherry Dr. and Mrs. Barry I. Samuels Mr. Herman G. Rowland, SR. The Honorable Harvey Schneider and Mrs. Dr. Veronica Selinko-Curran and Mr. Michael Mr. and Mrs. Austin Sherwood Mrs. Betty Claire Samuels Mr. Kenneth Rowland Marilyn Lee Schneider F. Curran Mr. Joseph A. Shewski Mrs. Marie R. Samuels Mrs. Peggy Rowley Mr. and Mrs. Jay R. Schneider Mr. and Mrs. Jerome Sella Mrs. Francis A. Shields Mr. and Mrs. Michael Samulin Mr. L. Peter Roy Mr. and Mrs. Michael Schneider Ms. Lauren Sella Mr. and Mrs. John H. Shields II San Antonio Area Foundation Karen and Scott Rozzell Mr. and Mrs. Robert W. Schneider Ms. Carolyn Sellers Ms. Shirleyann Mr. and Mrs. Adalio T. Sanchez Estate of Odette M. Ruben Trey and Debi Schneider Karen Abramson Selzer and John Scott Ms. Sogand Shodja Mrs. Caroline B. Sanders Podsednik Mr. and Mrs. Jerry Rubenstein Schneider Electric USA, Inc. Mr. and Mrs. Derek W. Shoobridge Mr. and Mrs. Harold H. Sanders Seneca Resources Corp. Dr. and Mrs. William S. Rubenstein Schneider Family Fund of the Jewish Mr. and Mrs. Timothy P. Shook Dr. Sherri Lynn Sanders Mrs. Lindi Kooke Senez The Jerry and Maury Rubenstein Foundation Communal Fund Shooting for a Cure Mr. and Mrs. Ronald P. Sandmeyer, Jr. David Senez Jr. Foundation Mr. Philip Rucka Mr. and Mrs. David Schnell Ms. Jennifer L. Shufelt Mr. and Mrs. Patrick B. Sands Sensient Technologies Foundation Inc. Mr. and Mrs. Gerry C. Rudd Joan Weingarten Schnitzer Ms. Patricia Shure Mrs. Cindy Sanford Sephardic Hospital Fund Mr. Terrence L. Ruddick Cynthia Schoeller Mr. Paul J. Sides, JR. Sanofi-Aventis U.S. Charitable Trust Septembeard Mr. Michael Rudelson Ms. Pamela B. Schoen Mrs. Anna Sie Mr. Luis Carlos Sarmiento Serene LLC Mr. and Mrs. Gary K. Ruff Mr. Carl Schoener Anna and John J. Sie Foundation Mrs. Luz Angela Sarmiento and Mr. Antonio Dr. and Mrs. Antonio C. Serna IV J. D. Ruffolo Family Foundation Dr. Myron Scholes Muriel F. Siebert Foundation Ardila Mr. and Mrs. Vernon A. Sevier, Jr. Mr. and Mrs. Eric C. Ruhlin Susan and David Scholes Bobbi and Gary Siegel Mr. and Mrs. Christopher Sarofim Mr. and Mrs. Collin Sewell Mr. Charles J. Ruhmann IV Mr. and Mrs. Jack W. Scholl Bobbi and Gary Siegel Family Fund of the Mr. Fayez S. Sarofim Peggy and Carl Sewell Nancy and Clive Runnells Foundation Dr. and Mrs. Don F. Schomer Jewish Community Foundation of New Mr. and Mrs. John Sarraf Sewell Village Cadillac Dr. Mary Runnels Mr. Kurt E. Schon Mexico Mr. and Mrs. Laurence R. Saslaw Mr. and Mrs. Nasser Shadparvar Mr. Ron Runnels The Schon Charitable Foundation Sigma Phi Epsilon Fraternity - Texas Delta Mr. and Mrs. Trebes Sasser Mr. and Mrs. Mel A. Shaftel Estate of William A. Runnels III Mr. and Mrs. John D. Schoolfield Signature Real Estate Services, Inc. Mr. and Mrs. Tom Saucier Shah Smith & Associates, Inc. Mr. Orville Rupell Mr. and Mrs. Richard D. Schreiber Mr. Leonard L. Signeski The Saudi Arabian Cultural Mission Mr. and Mrs. Lamar Shane, Jr. Mr. Perry V. Rupp Mrs. Sandra S. Schremp Mr. Robert E. Sikes Judy and Henry Sauer Mrs. Abie Shanks Dr. Robert A. Rupp Mr. Andrew C. Schroeder Mrs. Sue C. Sikes Mr. and Mrs. Hugh H. Saum III Mr. Jeff Shannon Mr. and Mrs. Edward J. Ruppert Mr. and Mrs. Fred Schroeder Mr. and Mrs. Ronald Silber Mr. and Mrs. Dan C. Savage Ms. Kerry A. Shannon and Mr. Steve Byrne Mr. W. Marvin Rush Mr. LeRoy H. Schulz, Jr. Silicon Valley Community Foundation Mrs. Una Savoie Dr. and Mrs. Tzu-Fann Shao Mr. and Mrs. Thomas V. Rushing Mr. and Mrs. Leo R. Schuster, Jr. Mr. Ebed M. Silva Mr. and Mrs. Wayne Sayatovic Marc and Jeri Shapiro Mr. and Mrs. Todd Rushing Joan & Leo Schuster Charitable Trust Dr. and Mrs. Bernard Silver Mr. Dennis Sbach Mr. Steven J. Shapiro Mr. and Mrs. Derral Russell Schwab Charitable Fund Silver Eagle Distributors SBSB Law PLLC Steve and Trish Shapiro Family Foundation Mr. and Mrs. Gene G. Russell Mr. Roger W. Schwandtner Marvin Silverman Trust Mr. John F. Scarborough Mr. and Mrs. Rich Shappard Mr. R. Kevin Russell Ms. Catherine M. Schwartz Sheila Silverman Trust Ivy and Joe Scarpinato Mr. and Mrs. Mehdi Sharifian Mr. Roy D. Russell Mr. and Mrs. Joseph M. Schwartz Mr. and Mrs. Larry Silverstein Mr. and Mrs. Stephan Schaar Mrs. Marlene J. Schwartz Ms. Catherine A. Sharkey Mr. and Mrs. Randy Sim Mr. Stephen Dale Russell and Ms. Cathy L. Mr. and Mrs. Donald J. Schade Layton Mr. and Mrs. John F. Schwarz Mary and Patrick Sharkey Mrs. Suzy Simar Mr. and Mrs. Jamie Schade Mrs. Vale Asche Russell Alan and Marilyn Schwedel Estate of Lucy Lane Sharp Ms. Shannon H. Simek Leah R. & Alfred E. Schaefer Charitable Mr. John C. Schweitzer Mr. and Mrs. Richard C. Sharp Mrs. Annette C. Simmons Mr. Michael Russo Foundation Mrs. Carole R. Sclafani Mr. and Mrs. James A. Shaughnessy Ellen C. L. Simmons and Family

61 MD Anderson Annual Report

Mr. and Mrs. Scott Simmons Mr. and Mrs. Howard Sinor, Jr. Mr. and Mrs. Damir S. Skerl Mr. and Mrs. Michael L. Slive Mr. and Mrs. Darrell Smith Mr. Thomas D. Simmons, Jr. SIR Foundation Mr. and Mrs. James W. Skidmore Mr. and Mrs. Melvin Sloan Mr. and Mrs. David H. Smith Mr. Tony A. Simmons Mr. and Mrs. Eric C. Sirgo Ms. Lillian Susan Skiles Mr. and Mrs. Albert H. Small Mr. Edwin Bomer Smith Simmons & Company International Mr. and Mrs. Steve Sirmon Ms. Marlise C. Skinner Small Army For A Cause, Inc. Mr. and Mrs. Forrest M. Smith III Ms. Morene Simon Mr. and Mrs. John J. Sisler Mr. and Mrs. Richard H. Skinner Don and Lori Smart Mr. Franklin R. Smith Mr. Herbert D. Simons Ms. E. R. Sisson Dr. Jerald L. Sklar Mr. and Mrs. Frank M. Smeal Gaylyn and Larry Smith Mrs. Jami Simons SIUT North America, Inc. Mr. and Mrs. Cory Slagle Ms. Alice U. Smith Mr. and Mrs. Harvey W. Smith, Jr. Ms. Sydney Simons Mr. Bill Sjolander Mr. and Mrs. Denys R. Slater, Jr. Mr. and Mrs. Billy A. Smith J. Chance Smith Estate of Cecil P. Simpson SK Foundation Mr. and Mrs. Gene Sledge Mr. Bruce C. Smith Dr. and Mrs. James A. Smith Mr. and Mrs. Elvin C. Simpson, Jr. Mr. Mark Skaggs Mr. and Mrs. Jack W. Sledge Mr. and Mrs. Bruce H. Smith Mr. Jason O. Smith Ms. Ora Lee Sims Mr. and Mrs. Millard L. Skaggs Mr. and Mrs. Steven Sletten Mr. and Mrs. Bubba Smith Mrs. Jimmie Miller Smith Mr. and Mrs. Donald R. Sinclair Mr. and Mrs. Michael B. Skalka Mr. and Mrs. William T. Slick, Jr. Mrs. Catherine C. Smith Mr. Karl Russell Smith, Jr. The Paul E. Singer Foundation Mr. and Mrs. Harry J. Skefos Alan B. Slifka Foundation Mr. Charles Aubrey Smith, Jr. Mr. Kenneth James Smith

Anderson Assembly Members

Since its inception in 1989, The Anderson Assembly has recognized those whose support and financial contributions have enabled MD Anderson’s continued growth and progress. Listed here are members who have committed $1 million or more through cash gifts, documented cash pledges, irrevocable planned gifts and/or charitable remainder trusts to support MD Anderson programs. Mr. and Mrs. Jerry Abbott The Brown Foundation, Inc. El Paso Corporation The Hawn Foundation Addi’s Faith Foundation David Bruton, Jr. Charitable Trust The Margaret and James A. Elkins, Jr. Foundation Head for the Cure Foundation Dr. Miriam & Sheldon G. Adelson Medical Research Harry Graves Burkhart III The Ellwood Foundation The Hearst Foundations Foundation Burlington Resources Entertainment Industry Foundation Miss Lyda Hill Mr. and Mrs. Avinash C. Ahuja Burroughs Wellcome Fund Exxon Corporation Hoffmann-LaRoche, Inc. Mr. and Mrs. Mark W. Albers Charles Butt ExxonMobil Foundation Estate of George S. Hogan/Scott Kochran, Trustee Joan and Stanford Alexander Kathleen Cailloux Family Foundation Diane Lokey Farb Mike Hogg Fund Mr. and Mrs. Albert B. Alkek The Cain Foundation Farmer Family Foundation The Hoglund Foundation American Brain Tumor Association Gordon and Mary Cain Foundation Mr. and Mrs. G. Steven Farris Don L. and Julie Holden Foundation American Cancer Society CaP CURE The Favrot Fund Houston Endowment Inc. Amgen, Inc. Ann and Clarence P. Cazalot, Jr. Carolyn Grant Fay Roy M. and Phyllis Gough Huffington Homer Ammann Trust Ting Tsung and Wei Fong Chao Foundation Mr. and Mrs. David L. Feavel IBC Foundation Anadarko Petroleum Corporation The Chaplaincy Fund, Inc. Mr. and Mrs. George A. Finley, III Interferon Foundation Estate of June Carol Anderson Chapman Foundations Management, LLC Mr. William B. Finneran Introgen Therapeutics, Inc. M. D. Anderson Foundation Ms. Lois Chiles and Mr. Richard Gilder Ray C. Fish Foundation Ben and Catherine Ivy Foundation Mrs. Rita Anderson China Medical University and Hospital/ Louis & Gloria Flanzer Charitable Trust Mr. and Mrs. Joseph D. Jamail, Jr. Chang-Hai Tsai Mr. and Mrs. Barry G. Andrews David and Judy Fleischer Judith and Weldon Jaynes Mr. and Mrs. Arthur Ciocca Apache Corporation Flight Attendant Medical Research Institute, Inc. The Honorable Brenda L. Johnson and CLL Global Research Foundation Mr. J. Howard Johnson James B. & Lois R. Archer Charitable Foundation Maria & Raymond Floyd Family Foundation The Cockrell Foundation M. G. and Lillie A. Johnson Foundation, Inc. Laura and John Arnold Foundation Mr. and Mrs. Ford-Petrin Mr. and Mrs. Gus Comiskey, Jr. Jane and John Justin Foundation AstraZeneca LP Mr. and Mrs. George E. Foreman The Honorable and Mrs. Peter R. Coneway Mr. and Mrs. Michael Kadoorie Avon Foundation for Women Nancy and Steve Fox ConocoPhillips The Jake and Nina Kamin Foundation Mr. and Mrs. James A. Baker, III Freeport-McMoRan Copper & Gold Foundation Conquer Cancer Foundation of the American John Kanzius Cancer Research Foundation Mr. and Mrs. Perry R. Bass Society of Clinical Oncology Estate of Frank H. Gabriel Abraham J. & Phyllis Katz Foundation Paul Beck Mr. and Mrs. Jack B. Corey Mr. and Mrs. James L. Gallogly Kavanagh Family Foundation Robert A. and Renée E. Belfer Foundation The James M. Cox, Jr. Foundation Pamela and Wayne Garrison W. M. Keck Foundation Estate of Gwin C. Blair Robert Page Crozer Mose A. Gimbel The John G. and Marie Stella Kenedy Memorial Mr. and Mrs. Jack S. Blanton, Sr. Mr. and Mrs. Edward E. Crutchfield Golfers Against Cancer Foundation Dr. Eric Bodin and Pat Hewlett Bodin The Cullen Foundation Mr. Harold V. Goodman Mr. and Mrs. James C. Kennedy The Bosarge Family Office The Cullen Trust for Health Care Mr. and Mrs. William H. Goodwin, Jr. Khalifa Bin Zayed Al Nahyan Foundation Breast Cancer Research Foundation Mrs. Delmer W. Dallas Mr. and Mrs. Steven L. Gordon Killam Family Foundation Bristol-Myers Squibb Company Christopher and Susan Damico Mr. and Mrs. F. O’Neil Griffin Kimberly-Clark Foundation Bristol-Myers Squibb Oncology The Charles A. Dana Foundation Estate of Dr. and Mrs. Ferenc Gyorkey Sidney Kimmel Foundation The Broach Foundation for Brain Cancer Research The Sidney and Charline Dauphin Foundation Mr. and Mrs. Paul R. Haas Kinder Foundation Mrs. Eleine Brooks Mr. William J. Doré, Sr. Maureen and Jim Hackett/Hackett Family Foundation Robert J. Kleberg, Jr. and Helen C. Kleberg Mr. and Mrs. Henry T. Brooks John S. Dunn Research Foundation Halliburton Foundation Mr. Kyle C. Brooks Raymond A. Jr. and Roslyn S. Eckstein Foundation The Hamill Foundation Mr. and Mrs. Melvyn N. Klein 62 PARTNERS IN MAKING CANCER HISTORY

Mr. and Mrs. L. R. Smith Mr. and Mrs. Steven M. Smith J & J Smythe Family, LLC Mrs. JoAnn P. Soderquist Southern Distributing Co., Inc. Mr. Larry Smith Mr. Stuart H. Smith Mr. and Mrs. Malcolm Sneed III Ms. Evelyn Soforenko Southern R&R Construction, Inc. Larry J. and Marsha Smith Mr. Terence J. Smith Mr. and Mrs. Thomas M. Snell The Harry and Estelle Soicher Foundation Southwest Bank Mr. Lawrence L. Smith Mr. and Mrs. W. Brett Smith Mr. James Stephen Snider Mr. and Mrs. Harvey Solway Southwest Oncology Group Mr. Louis E. Smith Ryan Smith ACC Cancer Research Foundation Mr. and Mrs. Currin Snipes The Somekh Family Foundation Southwestern Energy Company Mrs. Lynn Smith Clara B. & W. Aubrey Smith Charitable Mr. and Mrs. J. Dudley Snyder Somerset High School Student Council Mr. and Mrs. David N. Sovchen Mr. and Mrs. Mark D. Smith Foundation Mrs. Joan M. Snyder Mr. and Mrs. Paul G. Somerville Mr. and Mrs. Rod A. Sovereign Mr. and Mrs. Michael A. Smith Vivian L. Smith Foundation Mr. John C. Snyder Mr. and Mrs. Robert D. Somerville Mr. Richard Sowden Onnie Leach Smith The William A. and Madeline Welder Smith Ms. Rosanna Snyder Mr. John A. Sommers Mr. and Mrs. Rex L. Spahn Mr. and Mrs. Paul H. Smith Foundation Mr. and Mrs. Roy Snyder Mrs. Marianne D. Sondak Ms. Catherine L. Spain and Mr. Dean Mr. Randlow Smith Mr. Gerrit J. Smitskamp Ms. Ruth Snyder Frances and Gregory Sones Strombom Mr. Robert G. Smith, Jr. Mr. and Mrs. Mark S. Smock G. Whitney Snyder Charitable Fund Ms. Xiaomei Song Mrs. Joyce C. Sparks Mr. and Mrs. Robert L. Smith Mr. Paul N. Smolen Mr. Robert Sobczak Mr. Lazern O. Sorensen Ruth Parr Sparks Foundation Mrs. Shirley Ann Smith Mrs. Barbara Harab Smolowitz Mr. and Mrs. Robert E. Socia Dr. Nancy and Mr. John Soteriou Mrs. Heather F. Spector Mr. Stephen F. Smith Mr. and Mrs. James T. Smythe Social and Environmental Entrepreneurs, Inc. Mr. David Sour Spectra Energy Foundation

Estate of Ellen F. Knisely Red and Charline McCombs The Reynolds and Reynolds Company Sunoco LP Mr. and Mrs. David H. Koch John P. McGovern Foundation RGK Foundation Mr. and Mrs. David M. Talla Estate of Lillian C. Koehler The Robert and Janice McNair Foundation Sid W. Richardson Foundation Ms. Electa C. Taylor Susan G. Komen Breast Cancer Foundation Mr. and Mrs. Charles D. McVean Rising Tide Foundation Dr. and Mrs. John C. W. Taylor Saranne and Livingston Kosberg J. Ralph and Lillian H. Meadows Corbin J. Robertson and Wilhelmina C. Robertson Smith T.L.L. Temple Foundation The State of Kuwait Melanoma Research Alliance Mr. and Mrs. James C. Roe Tenneco Inc. Mr. and Mrs. William Kyte Mr. and Mrs. LeRoy Melcher Ben, Julie, and Regina Rogers Texas 4000 For Cancer Estate of Emma Lou Lancaster Mr. and Mrs. Allen A. Meyer Mr. T. Gary Rogers Texas Federation of Business and Professional Estate of Nathan W. Lassiter Estate of Anne W. McGraw Midgley Dr. Marnie Rose Foundation Women’s Clubs, Inc. Helen H. Laughery Mr. and Mrs. George P. Mitchell Estate of David Rosenstone William G. and Dorothy K. Theisinger Mrs. Theodore N. Law Estate of A. Clifton Mock Rotary Club of Houston Foundation, Inc. Mr. and Mrs. Jon L. Thompson Mr. and Mrs. C. Berdon Lawrence W. A. “Tex” and Deborah Moncrief, Jr. The Jerry and Maury Rubenstein Foundation Timken Foundation of Canton Sun Lee, CRNA Monteleone Family Foundation Damon Runyon Cancer Research Foundation Tony’s Prostate Cancer Research/Tony Masraff Mr. and Mrs. Howard Lester Estate of Mary E. Montrose Mr. Andrew E. Sabin Mrs. Shirley W. Toomim Leukemia & Lymphoma Society Jean H. and Jerry J. Moore Dr. Raymond and Beverly Sackler Mr. and Mrs. Morton L. Topfer Mr. and Mrs. Milton Levit and Family Estate of Louise J. Moran Mr. and Mrs. Federico Sada Triumph Over Kid Cancer Foundation Rochelle and Max Levit Estate of Frances Morse Samsung Electronics America, Inc. Estate of Harold L. Tull Mr. and Mrs. Jack Lewis, Jr. The Honorable and Mrs. Robert A. Mosbacher, Sr. The A. R. “Tony” and Maria J. Sanchez Family Beverly and John Turner Mr. and Mrs. Thomas C. Liebman Ralph E. and Virginia Mullin Foundation Herbert H. and Katharine Moore Unsworth LIVESTRONG Multiple Myeloma Research Foundation SBC Foundation The V Foundation For Cancer Research Mr. and Mrs. John T. Lockton, III Mr. and Mrs. James J. Mulva Schecter Family Foundation Vale-Asche Foundation The Gillson Longenbaugh Foundation Estate of Wanda L. Murry Schering-Plough Corporation Mr. and Mrs. J. Virgil Waggoner The Longwell Family Foundation/Norma and Harry Ms. Sara Brown Musselman Estate of Gene Schulze Ms. Lindsay Lavine Webster Longwell National Breast Cancer Foundation, Inc. Estate of Dr. Sam Schwartzberg Mr. William M. Webster IV Mr. and Mrs. Ben F. Love National Foundation for Cancer Research Mr. Solon Scott, III The Weingarten Schnitzer Family Mr. Jho Low/Jynwel Charitable Foundation Limited The Robert R. and Kay M. Onstead Foundation Mr. Thomas D. Scott Ms. Donna Arp Weitzman and Mr. Herbert D. LUNGevity Foundation The John M. O’Quinn Foundation Scurlock Foundation Weitzman The Lustgarten Foundation The Ovarian Cancer Research Fund Peggy and Carl Sewell The Robert A. Welch Foundation Lymphoma Research Foundation Elsa U. Pardee Foundation Estate of Jeanne F. Shelby Neva and Wesley West Foundation LyondellBasell Industries Ray Park and Family Shell Oil Company Foundation E. L. Wiegand Foundation The Harry T. Mangurian, Jr. Foundation, Inc. The Parker Foundation Cecil P. and Anna C. Simpson Harry Carothers and Olga Keith Wiess Jed Manocherian Pennzoil-Quaker State Company Clara B. and W. Aubrey Smith Charitable Foundation J. Brooks Williams Marathon Oil Corporation Phillips 66 Estate of Mowry Smith, Jr. Mr. and Mrs. John Eddie Williams, Jr. The G. Harold and Leila Y. Mathers Charitable Mr. T. Boone Pickens R. E. “Bob” and Vivian L. Smith Mrs. Margaret Alkek Williams Foundation Mr. Hanns Pielenz The William A. and Madeline Welder Smith Mr. and Mrs. Melvyn L. Wolff M. D. Matthews Foundation Mr. Gene Rainbolt Foundation The Wortham Foundation, Inc. The Mayer Family Jack and Beverly Randall Mrs. Terry Sonnevil Karen Buchwald Wright Maynard Family Foundation The Randalls Foundation Ron and Tycha Stading WWWW Foundation, Inc. (QuadW) Lowry and Peggy Mays Bernard and Audre Rapoport Mr. and Mrs. Charles W. Stiefel Mr. and Mrs. Oscar S. Wyatt, Jr. Del and Dennis McCarthy Ms. Judi A. Rees The Sunderland Foundation The Anne and Henry Zarrow Foundation

This historical listing reflects the original names of individuals, foundations and corporations as they were brought into The Anderson Assembly. 63 MD Anderson Annual Report

Gerry and J.J. Spedale STCube Pharmaceuticals, Inc. Carl J. and Glenda W. Streva Mr. and Mrs. George Swytnyk Texas Capital Bancshares, Inc. Estate of Terry Speed Mr. and Mrs. Michael J. Stehling Ms. Judy A. Stringer Mr. and Mrs. David S. Sykes Texas Gulf Coast CFC Community Health Mr. William T. Speller E. F. Stein Mr. and Mrs. Robert P. Stringfellow Mr. and Mrs. Mellick T. Sykes, Jr. Charities Mary John Spence Mr. and Mrs. Phil Steinberg Stripes LLC Gerald and Nancy Syler Texas Instruments Foundation Educational Peggy and Bob Spencer Dr. Tobi Steinhardt Dr. John R. Stroehlein Mr. Charles W. Synnamon Matching Gift Program Mr. Mark Spenrath Dr. and Mrs. Fred Steinman Mr. David Stroh Mr. and Mrs. Charles H. Szabuniewicz Texas Methodist Foundation Mr. John P. Spergl Mrs. Betty Stelzer Dr. and Mrs. David R. Strome Texas Neurofibromatosis Foundation Mr. Jan W. Spin Mr. and Mrs. John D. Stenson Ms. Lisa Strong Texas Prairieland Foundation Mr. James A. Spinks Dr. Maria Stephan-Laham and Dr. James L. Brody Strong Foundation T Texas Presbyterian Foundation Mr. Joel I. Spira Laham Mr. and Mrs. Jim Stroud Texas Rangers Baseball Foundation Ms. Cynthia Stephens The T. Rowe Price Program for Charitable Mr. and Mrs. Roy J. Textor The Joel & Brenda Spira Foundation Structural Concepts Giving Mr. and Mrs. John J. Stephens Mr. and Mrs. William L. Thacker III Mr. and Mrs. Kenneth F. Spitler Deana McNorton Strunk and Paul Strunk Mrs. Elizabeth Y. Taber Mr. Mark Stephens Miss Tiffany Thai Dr. Craig A. Spletzer Leslie D. Strupp Mr. and Mrs. Albert S. Tabor, Jr. Mr. and Mrs. James M. Stephenson Thai Express Inc. Mrs. Mary F. Spletzer Steven and Gina Stryker Mr. and Mrs. Yasuro Tachibana Mr. and Mrs. Randall L. Stephenson Mr. Chester Allen Thames, Jr. Sponsel Miller Greenberg Pllc STS Foundation Takeda Pharmaceuticals North America, Inc. Mr. and Mrs. Mike Stepp The CM Group Sport Clips Mr. Michael D. Stuart Mr. and Mrs. Everette L. Talbot Dale and Lola Spradley Mr. and Mrs. Roderick D. Stepp Mr. and Mrs. James E. Stueve The Conn/Fertitta Charitable Foundation Mrs. Mary Lynn Talbot-Davidson and Mr. The Guteman Family Foundation Estate of Langford Spraggins Mr. and Mrs. Dan P. Ster Mr. and Mrs. David S. Stukalin William F. Davidson The Oshay Family Foundation Mr. and Mrs. John Springer Mr. and Mrs. M. C. Stetzer Dr. Janet P. Stukalin and Dr. Ronald Stukalin Mr. and Mrs. Tony L. Talbott The Pasquinelli Foundation Mr. and Mrs. Jeff Springmeyer Mr. John Stevenson and Ms. Robyn Rothman Mr. and Mrs. Frederick W. Stumpf Mr. and Mrs. David M. Talla Mrs. Castine B. Theriot Springmeyer Family Mr. and Mrs. H. Leighton Steward Mr. Justin K. Stuppy The Talla Family Revocable Trust J. Theriot Mr. and Mrs. Michael E. Sprintz Alan G. and Kathy Kurtin Stewart Mrs. Mike P. Sturdivant, Sr. Mr. Alan H. Talley Mr. and Mrs. Donald L. Thiel Mr. Scott A. Sproull Mr. Don A. Stewart, Jr. Mr. and Mrs. William B. Sturgis Mr. G. Richard Talley Mr. Edward E. Thiele SSS Foundation Mr. and Mrs. Douglass M. Stewart Mr. and Mrs. John H. Styles, Sr. Bob Tallman’s Charities, Inc. Mr. and Mrs. Rick Thielke Mr. Jack B. St. Clair Mr. and Mrs. Michael W. Stewart Mr. Nelson Suarez Talonvest Capital, Inc. Mr. Mario Ricardo Thiem St. John Paul II Catholic School Mr. and Mrs. Richard R. Stewart Ms. Shalini Bala Subramaniam Mr. Vincent K. Tam Lt. General Billy Marshall Thomas St. Jude Medical, Inc. Mrs. Leona R. Stich Mr. Mark M. Suedhoff Mr. Brian J. and Rebecca Tanner Mrs. Cathy P. Thompson St. Martha Catholic School Mr. and Mrs. Charles W. Stiefel Duane and Denise Suess Mr. Charles R. Tanner Mr. and Mrs. Charles Thompson Mr. James P. Stabler Mr. and Mrs. John D. Stiefel Sugarland OMS Mr. R. E. Tanner Mr. Drew Thompson Stache & Associates LLC Mr. and Mrs. Joe A. Still In Memory of Patti Sulkin Brian & Rebecca Tanner Family Foundation Mr. and Mrs. Jon L. Thompson Mr. Howard G. Stacker Mr. and Mrs. William M. Stillman Mr. and Mrs. Donald M. Sullivan Mrs. Beatrice B. Taplin Dr. and Mrs. Peter K. Thompson Debbie and Bill Stacy Mr. and Mrs. C. David Stinson Mr. and Mrs. Gerald Sullivan Mrs. Arlene Tash Mr. Richard J. Thompson The Stading-Younger Cancer Research Mike and Pamela Stinson Ms. Mari Sullivan Mr. and Mrs. Burton M. Tashman Thompson & Associates Foundation Mr. Richard Stinson Mr. Richard Sullivan The Brett Tashman Foundation Cathy and Dwight Thompson Foundation Mrs. Claudia J. Stafford Mr. and Mrs. John L. Stiteler Mr. and Mrs. Robert L. Sullivan, Jr. Mr. Jerry Tate Stage Stores, Inc. Stock Consulting Group, LLC Mr. and Mrs. John M. Suman The Jon L. and Beverly A. Thompson Judy and Charles Tate Foundation Mr. and Mrs. Allen C. Staggers, Jr. Ms. Charlotte C. Stockard Mr. and Mrs. Carroll E. Summers, Jr. Mr. James E. Tatum Dr. and Mrs. Kevin G. Thomson Mr. Hugh I. Stahlman III Ms. Mary Anne Stockard Summit Medical Group The Tatum Family Foundation Mr. William L. Thorpe Mr. and Mrs. Fred E. Staible Mr. and Mrs. Gregory W. Stockholm Mr. Cal Sumrall Bonnie and George Taubel Thorpe Specialty Services Corporation Mr. Gillian Staley Mr. and Mrs. John H. Stockton Mr. Charles Sunderland Mr. and Mrs. Alford I. Taylor Ms. Mary L. Thorstenberg Linda and Joe Staley Mr. Charles Stoddard The Sunderland Foundation Mr. and Mrs. Craig Taylor Mr. Burnis E. Thrash Staley Business Partnership, Ltd. Gayle and Paul Stoffel The Sunoco Foundation Mr. David Taylor Threshold Pharmaceuticals, Inc. Mr. and Mrs. Charles P. Stall Ms. Sara S. Stokes Mr. and Mrs. Mark T. Sunwall Estate of Electa C. Taylor Thunder Run Land & Cattle, LLC Ms. Brenda Stallings Mr. and Mrs. Tom J. Stollenwerck Mr. and Mrs. Kurt Suprynowicz Mr. and Mrs. Jack Taylor Mr. and Mrs. Brian L. Thurman Stand Up To Cancer Laura Ziskin Prize Mr. Howard L. Stone Dr. and Mrs. Ali G. Surek Mr. and Mrs. John N. Taylor Mr. and Mrs. Norris Tibbetts Standard Sales Company, L.P. Mr. and Mrs. James Clif Stone Surety Management, Inc. Ms. Wendy S. Taylor Mr. Warren W. Tichenor Mr. William Standera Dr. Norma K. Stone and Mr. Donald J. Stone Mr. and Mrs. Sam L. Susser Ms. Mary Ann Teague Mr. and Mrs. Bob Tidwell Mr. Todd Standlee The Storehouse Foundation The Sutaruk Foundation Team Nat Foundation Inc. Mr. and Mrs. Don Tidwell Mr. George R. Standridge Mr. Robert E. Storey, Jr. Mr. and Mrs. John L. Sutey Ted W. Walters and Assoc., LLC Tilford, LTD Mrs. Jo Ellen Stanfield Celika Storm Mr. and Mrs. James D. Sutton Susan and Patrick Teixeira Ms. Kimberly A. Tiller Stanford C. Bernstein and Co., Inc. Mr. and Mrs. John W. Storms Mr. and Mrs. L. E. Sutton Mr. and Mrs. Kenneth Tekell Louis D. Tilotta Charitable Foundation Mary J. and Paul D. Stang Mr. and Mrs. N. E. Stouder Linda and Rick Svoboda Mr. and Mrs. Thomas J. Tella II Timken-Sturgis Foundation Mr. and Mrs. Blair A. Stanicek Mr. and Mrs. Fred S. Stovall, Jr. Swalwell-Connor Family Foundation Inc. Mrs. Ellen Temple Mrs. Geraldine C. Timmermann John and Sharon Stankey Dr. Marilyn A. Stovall Mr. Bill Swanson T.L.L. Temple Foundation In Memory of Dr. Joseph Ting Mr. and Mrs. Bret Stanley Mr. and Mrs. George W. Strake, Jr. Mrs. Carene S. Swanson Mr. Lawrence P. Templet Mr. Terrence N. Tingley Mr. and Mrs. R. John Stanton, Jr. Strake Foundation Mr. and Mrs. Gary L. Swanson Mr. Robert N. Tenczar Ms. Ashley Tinley Mr. Michael L. Stanwood Charlotte and Terry Strange Gretchen Swanson Family Foundation, Inc. Estate of Edith Tener Mr. Phillip D. Tippen Mr. Danny J. Stark Strategia Therapeutics, Inc. Mr. Robert M. Swartz David B. Terk Foundation Louis Tiseo Lois and George Stark Stratford High School Mr. and Mrs. Stephen G. Sweet Mary and Mike Terry TLC Wealth Management Group, Inc. Mr. and Mrs. Steven Stark Stratford Playhouse Booster Club Mr. and Mrs. Thomas D. Swepston Mr. and Mrs. Michael D. Terry Dr. Teresa M. Todd and Dr. David L. Todd Stark Community Foundation Mr. and Mrs. Scott Stratton Mr. and Mrs. Robert L. Swickley Tesoro Foundation Todd Family Charitable Foundation Dr. and Mrs. John H. Starkey Colonel and Mrs. Tom J. Strauss Mr. and Mrs. Phelps Swift Mr. Wayne H. Teumer Mr. and Mrs. George W. Tolleson Mr. and Mrs. David W. Starowicz Ms. Edith Street Ms. Kimberlee Swig Tex Fed of B&PW Foundation, Inc Mr. and Mrs. John C. Tolleson State Employee Charitable Campaign Ms. Elaine Street Mr. and Mrs. Mark S. Swim Texas 4000 for Cancer Tolleson Wealth Management State Farm Agents, Employees, and Retirees Lucille Anderson Streeter Ms. Nettie Swinney Texas Aggregates, L.L.C. Mr. and Mrs. Eric Tom Mr. Daniel J. Staub Jannette and Gerald Streit SWM International Inc. Texas Business and Professional Women’s Tom Amoss Racing Stable Inc. Mr. and Mrs. Roger T. Staubach Mr. and Ms. Edward B. Strempel Mrs. Juanita E. Sword Foundation

64 PARTNERS IN MAKING CANCER HISTORY

Mr. and Mrs. Don Tomlin Dr. Daksha Turakhia and Mr. Bipin Turakhia Mr. V. H. Van Horn W Mr. and Mrs. Dewitt Waltmon Phuong Tonthat Mr. Randall J. Turk Ronald and Deborah Van Ness Dr. Xiangbo Wan Mr. Bill Toomey Turn’em Barrel Racing Association Van Zandt, Emrich and Cary W. F. Foundation Mr. and Mrs. MoKiang Wang Mrs. Shirley W. Toomim Mr. and Mrs. David O. Turner Dr. William R. Vance Mark and Debbie Waage Ms. Qingsu Wang and Mr. John G. Zvonar Toot’n Totum Food Stores, LLC Ms. Diane Turner Dr. George F. Vande Woude Wachtell, Lipton, Rosen & Katz Ms. Sue Hwa Wang Mr. and Mrs. Morton L. Topfer Mr. and Mrs. James G. Turner Mr. Donald VanDenbos, Jr. Mr. and Mrs. Bill Wade Dr. Xin Shelley Wang and Dr. Charles S. Topfer Family Foundation Mr. and Mrs. Langston Turner Mr. and Mrs. Richard H. Vander Meer Mr. and Mrs. Byron L. Wade Cleeland TopIQue Associates, Inc. Mr. and Mrs. Lawrence A. Turner Gary and Debby Vandergriff Mr. and Mrs. Michael J. Wadino, Jr. Mr. R. Wanner Torchy’s Tacos Ms. Carol A. Turni Mr. and Mrs. John C. Vanderhider Mr. John Wadsack Mr. Albert J. Ward, Jr. Mr. and Mrs. Shane Torr Mrs. Vernita J. Turpin Ms. Sasha Vanderhurst Mr. and Mrs. Robert Waechter Ms. Courtney Ward Mr. and Mrs. Donaldo E. Torres Tustin Mazda Mrs. Eleanor Vandeventer Dr. Elizabeth A. Wagar Mr. and Mrs. John M. Ward Mr. and Mrs. Victor M. Torres, Sr. Twang Partners, LTD Ms. Margaret Morrow Vandyken Ms. Glenna Wagenschein Mr. Newton E. Ward, Jr. Mr. and Mrs. Joe V. Tortorice, Jr. Drs. David J. Tweardy and Ruth Falik Vanguard Charitable Endowment Program Mrs. M. June Waggoner Mr. Troy Ward Total Petrochemicals USA, Foundation Mr. Roger M. Tweed Mr. and Mrs. S. Wil VanLoh, Jr. Mr. and Mrs. Stephen E. Waghorne Mr. Rick Wardlaw Total System Services, Inc. Mr. and Mrs. Kenneth L. Tye Mr. Douglas H. VanMiddlesworth Mr. and Mrs. Edwin A. Wahlen, Jr. Emily C. Ware Mrs. Fiona Toth and Dr. Robert S. Toth Colonel William H. Tyler Mrs. William W. Vann Mr. J. Dale Wainwright Mrs. Lezlye S. Ware DeeDee and Stephen Tou Mrs. Betty R. Tynes Mr. David R. Vannoy Mr. and Mrs. Andrew L. Waite Mr. and Mrs. Chauncey Edward Warner Mr. William Touchstone, Jr. Mr. and Mrs. H. Michael Tyson Mr. and Mrs. Mark VanStekelenburg Mrs. Pam Wakefield Mr. and Mrs. David A. Warner Ms. Pearl Tourville Mr. Curtis L. Vantine Ms. Barbara Walcott Ms. Megan Warren Mr. and Mrs. Robert M. Warren Jean and Severn Townsend U Mr. and Mrs. Adalberto Vara Mr. and Mrs. Tommy Wald Mrs. Sachiko P. Toy Varian Medical Systems, Inc. Barbara J. Walden Warren Charitable Foundation Toyota Motor Sales, U.S.A., Inc. Mr. Elkin Vasco Mr. Paul Warthen UBS Foundation USA Walden 100 Golf Charities Inc. Traf-Tex, Inc. Mr. and Mrs. Cesar S. Vasquez Mr. and Mrs. Tom Washburn Mr. and Mrs. James I. Uihlein Mr. and Mrs. Nathan Waldman Trafton Academy Daphne Vaughan Mr. and Mrs. Steven H. Wasserman Mr. and Mrs. Richard E. Uihlein Mr. John E. Waldron Transocean Offshore Mr. George C. Vaughan Mr. and Mrs. Jim B. Waterfield Ms. Jeanne S. Umstattd Sharon and Bob Waldron Transwestern Mr. Gerald E. Vaughan Ms. Ann H. Watkins Uncle Kory Foundation Mr. and Mrs. Kirby D. Waldrop Mr. and Mrs. Joseph L. Trapolino, Jr. Mr. and Mrs. Luther M. Vaughan, Jr. Dr. and Mrs. David L. Watkins Mr. Frederick L. Unger Estate of Jerry M. Waldschmidt Ms. Eileen Trautmann Susan and Gene Vaughan Mr. Robert Watkins Mr. and Mrs. Timothy J. Unger Mr. and Mrs. Daniel Walent Mr. and Mrs. Don Traweek Jim M. Vaughn Foundation Mr. and Mrs. Tony G. Watkins Unified Wealth Management, Llc Ms. Ann Wales Mr. James Traylor, Jr. Mr. and Mrs. Paul G. Veale, Jr. Howard Watson United Recovery Systems Mrs. Bonita D. Walker Mr. and Mrs. Travis Traylor, Jr. Mr. and Mrs. Andy Veit Mr. and Mrs. John C. Watson United Seafood, Inc. Mr. Dylan Walker Mrs. Betty J. Treadaway Mr. and Mrs. John Verity Mrs. Martha Watson United Way for the Greater New Orleans Area Mr. and Mrs. Foster Walker III Mr. Herbert E. Treder Mr. and Mrs. C. Richard Vermillion, Jr. Mr. and Mrs. Patrick S. Watson United Way of Central Maryland Mr. Jerry W. Walker Tres Aguilas Management, LLC Mr. and Mrs. Jim Vernon Dr. and Mrs. Philip C. Watt United Way of Central New Mexico Mr. Kenneth B. Walker Dr. Alfredo Trevino, Jr, MD, PA Mr. and Mrs. Van C. Vernon Ms. Marilyn Kay Watts United Way of Metro Chicago Mrs. LaVerne Walker Trillium, LLC Mr. Charles H. Verrill Mr. and Mrs. William A. Watts United Way of The Bay Area Mr. and Mrs. Michael J. Walker Mr. and Mrs. George L. Trimble III Ms. Mary Shelton Simpson Vescovo Mr. and Mrs. Robert C. Walker Mr. and Mrs. Alan S. Waxman The University of Texas Health Science Center Waxman Lawson Financial Mr. Gilbert Trimble at Houston Mr. and Mrs. Johnny J. Veselka Mr. Robert M. Walker Weatherford Chicken Express, LLC Mrs. Margaret C. Trimble UPMC Health System Mr. Samuel H. Vester, Jr. Mr. and Mrs. Ronald B. Walker Mr. and Mrs. Walter Weathers III Trinity Lutheran Booster Club Nick and Nancy Uppal Veterans of Foreign Wars Auxiliary Mr. and Mrs. Steven Walker Mr. and Mrs. Andy Weaver Ms. Mary J. Trinkle UT Health Northeast VFW Post 9187 Mr. and Mrs. Thomas L. Walker Dr. and Mrs. William R. Weaver Mrs. Lorraine M. Tripses Mr. and Mrs. George E. Uthlaut Mr. and Mrs. Thomas A. Viator WalkerStrong, Inc. Bill and Katie Weaver Charitable Trust Triumph Over Kid Cancer Foundation Ms. Darlene C. Utskot Mr. Dennis W. Vicars Mr. Donald E. Wall The Gil & Dody Weaver Foundation TRM Oncology, LLC Mr. and Mrs. Bob Utter Mr. and Mrs. John E. Vick Mr. and Mrs. Ken Wall Mr. and Mrs. Ryan Trott Mr. Sidney Victory, Jr. Mr. H. Dalton Wallace Mr. Charles Webb Mr. and Mrs. Kenneth Troutt Mrs. George F. Vietor Mr. and Mrs. Kent Wallace Mr. and Mrs. Michael R. Webb Mrs. Betty H. Trover V Mrs. Jamie L. Villegas Meridith and Brad Wallace Mr. Robert D. Webb, Jr. Mr. Edward R. Troy Mr. and Mrs. Gerald J. Vilmont Mr. Michael R. Wallace Mr. and Mrs. Terrence M. Webb Mrs. Linda M. Troy The V Foundation For Cancer Research Vilore Foods Company, Inc. Ms. Nancy V. Wallace Mr. Max Weber Mr. and Mrs. Brian K. Truby Mr. and Mrs. Vic E. Vacek, Jr. Mr. and Mrs. Michael T. Vincitore Mr. and Mrs. William F. Wallace Ms. Jeana Webster Leslie and John Trudeau Vadell Family Mr. James L. Vining Wallgren Environmental Services, Inc. Mr. William M. Webster IV Taylor Trudeau Cycle for Life Charitable Mr. and Mrs. Nitin Vaidya VISA International Mr. Robert Wallick Joan and Michael Wechsler Foundation Mr. and Mrs. Kenneth J. Valach Mr. Marc Viscogliosi Mr. Harold H. Walling Mr. and Mrs. David M. Weekley Mr. Robert E. True Mr. and Mrs. Hector C. Valadez Mr. Daniel Vizel Mr. Billy H. Walls David Weekley Family Foundation True Oil Enterprises, Llc. Valeant Pharmaceuticals VLM Services LLC Wal-Mart /Sam’s Club Foundation U. R. Weems TRUIST Jose L. Valencia, M.D. Mr. and Mrs. Gregory A. Vogt Mr. Hughes Walmsley Mr. Bobby Wehmeyer Mr. and Mrs. Dean B. Truitt Ms. Lori D. Valencic and Mr. William D. Pellerin Mr. John C. Vogt Mrs. Janice L. Walsh Mr. and Mrs. Robert E. Wehmeyer, Jr. Kirk and Julie Trussell Ms. Martha Jane Valent Mr. and Mrs. Jack Volkel Mr. Richard Walsh Mr. Russell E. Wehrman Mr. Joseph J. Tryba Valero Energy Foundation Volunteers: Madie Jones, Betty Bell, and Ms. Elisse Barbara Walter and Mr. Ronald Alan Mr. and Mrs. Christian C. Weichsel II Mr. and Mrs. Ronald W. Tuchschmidt Mr. and Mrs. Johnnie J. Valis Vivian Vann Stern Mr. and Mrs. S. Conrad Weil, Jr. Stephanie and Brad Tucker Vallone’s Ms. Gay Vondohlen Jean and Tom Walter The Diana and S. Conrad Weil, Jr. Family Drs. Mark and Bettina Tucker Mr. Frank Valuk Mr. and Mrs. Michael J. Vorst Mr. and Mrs. Joseph C. Walter III Foundation Mr. and Mrs. Robert B. Tudor III The Honorable Leticia Van de Putte Mrs. Wilma Jean Voss Walter Oil & Gas Corporation Dr. and Mrs. Frank Weiner Mr. and Mrs. George R. Tuerk Mr. and Mrs. Walter Van De Vijver Mr. and Mrs. Robb L. Voyles Mr. Arnold B. Walters Emily Weingarten Mr. and Mrs. Robert W. Tully Mr. William J. Van Devender Vs. Cancer Foundation Charles W. Walters The Weingarten Schnitzer Foundation, Inc. Tulsa Community Foundation Van Devender Family Foundation Mr. and Mrs. Ted W. Walters Mr. Daniel M. Weingeist Mr. Walter G. Tuma Roger and Diana Van Duzer Ms. Cindy Waltman Mr. and Mrs. Morris H. Weinstein

65 MD Anderson Annual Report

Ms. Laurie A. Weiss and Mr. John K. Mauser Allyson Whitney Foundation, Inc. Ms. Sue Ellen Wilson and Mr. Guy R. Lipof Dr. Kendra V. Woods and Mr. Brent P. Francis Mr. Brian J. Younger and Mr. Tige T. Stading Mr. Ron Weiss Mr. and Mrs. Robert H. Whitten, Jr. SuEllen and John Wilson Mr. Bill Woodson Younger Foundation Herb and Donna Weitzman Mrs. Sharon Wichterich Wilson Wolf Manufacturing Corporation Mr. William D. Woodul Colonel James Youngson Betty Marie Welch Mr. and Mrs. Bryan J. Wick Mr. James I. Wimsatt Mr. Peter W. Woolley Mrs. Adele Younkin Mr. James C. Welch E. L. Wiegand Foundation Mrs. Comfort Holt Winders Mrs. Kitty Wooten Mr. and Mrs. Dean F. Yow, Jr. Mr. and Mrs. John Welch Mrs. Cynthia Wiesner Ms. Carol Lynn Windham Mrs. Pauline Word Mr. and Mrs. Edward Yruma The Robert A. Welch Foundation Mr. Robert A. Wiggins Mrs. Carolyn Wingfield Mrs. Carol C. Workman Dr. and Mrs. W. K. Alfred Yung Mr. and Mrs. Raymond J. Welder III Estate of Brenda Joyce Wilburn Mr. and Mrs. Marshall Wingo Mr. and Mrs. David Workman Mr. Anthony Yurgaitis Mr. and Mrs. M. Weller Mrs. Elizabeth T. Wilde Mr. and Mrs. Joseph C. Winkler III Worldwide Institute of Medical Education Mr. Thomas Weller Mr. and Mrs. Charles John Wilder, Jr. Mr. Steve Winn Mr. and Mrs. Terry N. Worrell Wellesley Mazda John and Susan Wilder Foundation Mr. and Mrs. Richard P. Winnike Henry N. Worrest Z Wellmed Medical Management Mr. Lawrence E. Wilderman Dr. J. David Winningham Mr. and Mrs. Bob Worth Zachry Construction Corporation Carole and D. Brent Wells In Memoriam for Todd and Mark Wilems Mrs. Judith Winograd Ms. Diana G. Wortham Ms. Doris E. Zagon Ms. Linda S. Wells Mr. and Mrs. Wayne T. Wiles Mr. and Mrs. Herbert S. Winokur, Jr. Mr. and Mrs. Walter F. Worthington His Excellency Ardeshir Zahedi Mr. P. Michael Wells Mr. and Mrs. Michael E. Wiley The Winokur Family Foundation, Inc. Brad and Lois Wright Mr. and Mrs. Daniel R. Zak Dr. and Mrs. Samuel F. Wells, Jr. Wilfin Inc. Mrs. Totsye Winslow Mr. Gordon L. Wright Mr. and Mrs. Stephen Zak Mr. Sean Wells Mr. and Mrs. Johnathan N. Wilhelm Mr. Peter Winstead Janet and Arthur Wright Mr. Vicente C. Zamora, Jr. Mr. and Mrs. Steven T. Wells Mrs. Dolores K. Wilkenfeld Mrs. Candace Winter Mr. and Mrs. Joe Wright The Bradley Zankel Foundation, Inc. Employees of Wells Fargo W. David and Phyllis Wilkerson The David C. Winter Charity Ms. Karen A. Wright and Dr. Tom Rastin Mrs. Cheryl Zapata Wells Fargo Advisors, LLC Mr. Sam Wilkes David and Eula Wintermann Foundation Ms. Marla L. Wright and Mr. Nathaniel Jackson The Honorable and Mrs. Joseph Zappala Wells Fargo Community Support Campaign Mr. and Mrs. Craig Alan Wilkins Mr. and Mrs. William Winters Mr. Stephen R. Wright Mrs. Anne G. Zappe Wells Fargo Foundation Dr. Mary Ann Reynolds Wilkins and Dr. Robert Mr. and Mrs. Tom G. Winterton Lorraine and Ed Wulfe Stuart and Gaye Lynn Zarrow Mr. and Mrs. David D. Welsh B. Wilkins Ms. Barbara Winthrop and Mr. Jay Steinfeld WWWW Foundation, Inc. (QuadW) Mr. William B. Welte III Mr. and Mrs. Warren S. Wilkinson Dr. and Mrs. John L. Wirth Maxine and Jack Zarrow Family Foundation Mr. and Mrs. Merrill D. Wynne The Anne and Henry Zarrow Foundation Dr. Richard E. Wendt Mr. and Mrs. Dan Wilks Mr. Christopher Wirtz Dr. Mary Ann Wyss-Cummings Rosemary and Bruce Wentworth Dr. and Mrs. W. Darrell Willerson, Jr. Mr. and Mrs. Gordon Wise Mr. and Mrs. Jack Zbar Mr. and Mrs. Eugene Werlin, Jr. William Blair & Company, LLC Mr. and Mrs. William A. Wise Mr. Stephen A. Zeff Mr. and Mrs. Douglas E. Werner Ms. Anita M. Williams William and Marie Wise Family Foundation XY Mr. and Mrs. Steven A. Zenthoefer Estate of Joan S. Werner Ms. Beth Williams Watson W. Wise Foundation Mr. Douglas Zercoe Mr. and Mrs. Lon T. Werner Charles and Randa Williams Mr. and Mrs. Alan Wishnow XTO Energy Inc. Zeta Tau Alpha Foundation, Inc. Mr. and Mrs. Steven L. Wessinger Mr. Chris Williams Mr. James V. Withey Mr. Blaine Yamagata Zeta Tau Alpha Houston Alumnae Association Jeff West Memorial Fund Mr. and Mrs. Edward B. Williams Mrs. Cynthia G. Witte Dr. Stacy A. Yamasaki Dr. and Mrs. Lane D. Ziegler Mr. Warren G. Wester Mr. Gary R. Williams Witte Museum Mr. and Mrs. Wilson M. Yancey, Jr. Mr. Paul Ziegler Western Shade Cloth Charitable Foundation Gene and Colleen Williams Mr. and Mrs. Tom Allen Wittenbraker Mrs. Mary Jane Yanta Mr. and Mrs. Robert C. Ziegler Mr. and Mrs. Jerome M. Westheimer, Jr. Mr. George Williams Tom and Carolyn Wittenbraker Ms. Andrea J. Yarbrough Mr. and Mrs. Scott Ziegler Jerome Westheimer Family Foundation, Inc. Mr. and Mrs. Harold Mern Williams Dr. and Mrs. James Wittmer Fernando A. Yarrito Mr. and Mrs. Wayne P. Ziemianski Dr. Valda Kay Westmoreland Mr. and Mrs. Jack P. Williams, Jr. Mr. and Mrs. Brad Witty Dr. James R. Yates and Dr. Alba A. Ortiz Ziler Architects Westwind Helicopters, Inc Estate of James A. Williams Mrs. Helen Haynes Wofford Mr. Peyton Yates Ms. Merri Zilka Mr. Brenton Wetmore Mr. John A. Williams Mr. Michael D. Woinsky The Pat Yates Memorial Trust Mr. Charlie Zimmerman Weycer, Kaplan, Pulaski & Zuber, P.C. Kenneth C. (K.C.) and Theresa S. Williams Mr. and Mrs. Steven E. Wolf Dr. Neshat Yazdi and Mr. Shoa Abedi Mr. and Mrs. Martin Zimmerman Whataburger Mr. Kenneth R. Williams Cyvia & Melvyn Wolff Dr. Michael R. Yeaman Mr. and Mrs. Neil S. Zimmerman Mr. and Mrs. Patrick L. Whatley Mrs. Michel H. Williams Mr. and Mrs. David S. Wolff Mr. and Mrs. Kyle Yeates Mr. and Mrs. Thomas W. Zimmerman Mr. James E. Wheeler Mr. Ray P. Williams Mrs. Millicent Kaye Wolff Ms. Paulette Yeatts and Ms. Sheryl Carlson Mr. F. Richard Zitzmann Ms. Karen Wheeler Mr. Robert E. Williams Wolff Family Foundation Sonia and Gary Yeck Mrs. Marion C. Zoch & Family Mr. Zachary Wheeler Mr. Seth Williams Mr. and Mrs. Mark Wolfson Mr. and Mrs. Yuan-Lee Yeh Mr. Charles L. Zody Mr. and Mrs. William M. Wheless IV Sheridan and John Eddie Williams, Jr. Mr. and Mrs. Robert E. Wolitarsky Mr. and Mrs. Robert A. Yellowlees Mr. and Mrs. William C. Zollner The Wheless Foundation Ms. Terri Williams and Mr. Timothy J. Drexler Mr. and Mrs. William T. Womble Mr. Paul Yeomans Mr. and Mrs. Robert L. Zorich Mr. Wade H. Whilden, Jr. Mr. and Mrs. Tom W. Williams Women of Rotary Houston YES Prep Public Schools - Southwest The Zorich Family Foundation Mr. and Mrs. Edward E. Whitacre, Jr. Mr. and Mrs. Walter R. Williams Wonderful Giving Mr. and Mrs. Chong O. Yi Lois and Eric Zorn Mrs. Wilma Whitaker Williams Companies, Inc. Mrs. Teresa Wong Mrs. Molly C. Yieh Mr. and Mrs. James W. Zug Mr. and Mrs. A. Craig White Williams Elementary School Teresa and Jimmy Wong Family Foundation Mr. Him Yin Mr. and Mrs. Joseph F. Zullo Mr. and Mrs. Bob White The Paul J. Williams Foundation Mr. and Mrs. David Wood Mr. and Mrs. Samuel C. Yocum Mr. and Mrs. John E. Zumberge Mr. and Mrs. H. Blair White Mr. Ellis J. Williamson Mr. and Mrs. F. Michael Wood, Jr. Mr. and Mrs. Jeff Yoesel Mrs. Sophie Zurquiyah Estate of Helen N. White Mrs. Gerry Odom Williamson Mr. and Mrs. Jeffrey R. Wood Mr. Gregory D. York Mrs. Melanie Zwernemann Mr. and Mrs. Hunter H. White Dr. and Mrs. Hugh J. Williamson Mr. Joseph C. Wood, Jr. Mr. and Mrs. Johnny York Mr. Ron Zyzelewski Mrs. Joan I. White Mr. Donald W. Willingham Mrs. Karen L. Wood The Johnny and Lisa York Foundation Ms. Joy White James. A. and Marja A. Willis Mr. Larry D. Wood Mrs. Linda Yosten Dr. Lois White Willis Independent School District Mr. Larry W. Wood Mr. and Mrs. John F. Young In an effort to reduce printing costs, Ms. Marie C. White Wilrock LLC Dr. Tanya Wood and Mr. Don Wood Mr. and Mrs. Keith E. Young beginning next year, the Donor Honor Ms. Marilyn A. White Ms. Carolyn G. Wilson Mr. and Mrs. Thomas V. Wood Dr. Paul Young and Mrs. Susan Torn Young Roll will no longer appear in the The Honorable and Mrs. Mark White Mr. and Mrs. Herman T. Wilson, Jr. Ms. Sherry L. Woodard Mr. and Mrs. Richard Young print version of the Annual Report. Marilyn Ann White Charitable Foundation Mr. and Mrs. James A. Wilson Woodforest National Bank Mr. T. Michael Young This was a difficult, but critical, cost- Dr. Jill W. Whitehurst and Mr. Brad Whitehurst Mr. John Wilson The Woodlands High School Mrs. Vernon R. Young, Sr. Ms. Glenda G. Whiteley Mrs. Lonna Wilson Mr. and Mrs. Stephen R. Woodley Mrs. Virginia Young saving decision. We appreciate your Mr. and Mrs. Lowell D. Whitlock III Mr. Robert L. Wilson, Jr. Mr. and Mrs. Allan C. Woodruff Mr. and Mrs. William M. Young understanding in this matter, as well Mr. William B. Whitman Mr. and Mrs. Ron Wilson Ms. Mary M. Woodruff Young Texans Against Cancer - Houston as your continued support in Mr. and Mrs. Jon R. Whitney Scott Wilson and Laura King Mr. and Mrs. Carey A. Woods III Chapter Making Cancer History®.

66 Fiscal Year 2016 financial and statistical data Sept. 1, 2015 – Aug. 31, 2016

67 MD Anderson Annual Report

Sources of revenue FY 2012 FY 2013 FY 2014 FY 2015 FY 2016

Patient Revenue

Gross patient revenue (Includes inpatient, outpatient and professional services) $6,144,132,636 $6,582,112,827 $6,994,996,215 $7,567,179,285 $7,571,426,899

Deductions from gross patient revenue1 3,185,346,342 3,403,247,816 3,659,313,782 3,935,319,324 4,044,324,615

Net patient revenue $2,958,786,294 $3,178,865,011 $3,335,682,434 $3,631,859,960 $3,527,102,284

Restricted grants and contracts, philanthropy $426,455,579 $505,144,559 $421,761,275 $402,702,183 $466,883,217

State-appropriated general revenue 170,383,019 154,562,093 185,393,182 187,350,746 201,848,484

Auxiliary income2 36,957,473 40,674,618 41,502,690 44,808,473 42,462,462

Other income3 56,151,131 75,564,178 99,702,455 107,422,200 112,515,085

Investment and other non-operating income 87,098,290 180,428,432 328,881,907 121,624,475 129,632,830

TOTAL REVENUE $3,735,831,786 $4,135,238,891 $4,412,923,943 $4,495,768,037 $4,480,444,361

Sources of revenue (in millions)

$3,527.1 | Net Patient Revenue | 78.7%

$466.9 | Restricted Grants and Contracts, Philanthropy | 10.4%

$201.8 | State Appropriated General Revenue | 4.5%

$42.4 | Auxiliary Income | 0.9% $129.6 | Investment and Other Non-Operating Income | 2.5%

$112.5 | Other Income | 2.9%

1 Amounts discounted from established rates as a result of agreements with third-party payors, including Medicare, Medicaid and insurance companies. Also includes deductions associated with indigent care and bad debt. 2 Funds received from parking fees, valet services, dining facilities, hotel charges, gift shop sales and vending-machine sales 3 Includes tuition and student fees, Children’s Art Project sales, management fees and other sources 68 DATA

Uses of revenue FY 2012 FY 2013 FY 2014 FY 2015 FY 2016

Research $546,836,560 $588,664,553 $631,944,987 $668,243,371 $687,940,063

Instruction, academic support and public service 164,580,132 209,633,502 195,958,981 225,871,577 234,488,229

Patient care 1,880,230,560 2,013,554,826 2,055,617,566 2,369,972,993 2,642,145,329

Facilities and depreciation 460,445,328 471,935,938 486,793,306 508,973,014 550,277,895

Institutional support, auxiliary and other4 280,844,123 305,390,616 312,865,408 155,828,553 158,060,132

Allocation to capital plan (For future projects to replace and improve facilities and 402,895,083 546,059,455 729,743,695 566,878,529 207,532,714 technology)

TOTAL EXPENSES $3,735,831,786 $4,135,238,891 $4,412,923,943 $4,495,768,037 $4,480,444,361

Uses of revenue (in millions)

$207.5 | Allocation to Capital Plan | 4.6% $687.9 | Research | 15.4%

$158.1 | Institutional Support, $234.5 | Instruction, Academic Support Gross revenue by payor Auxiliary and Other4 | 3.5% and Public Service | 5.2% classification (in millions)

$550.3 | Facilities and $4,179.6 | Managed Care | 55.2% Depreciation | 12.3%

$2,642.1 | Patient Care | 59.0% $211.0 | Medicaid | 2.8%

$52.9 | Indigent | 0.7%

$327.5 | Other (International/Self Pay/Other) | 4.3%

$2,800.4 | Medicare | 37.0%

4 Includes support for parking, food and gift shop services, as well as general institutional support (e.g. information technology, human resources, administration, development activities, etc.) 69 MD Anderson Annual Report

Clinical profile FY 2012 FY 2013 FY 2014 FY 2015 FY 2016

Hospital admissions 26,726 27,905 27,761 28,167 27,391

Patient days 191,735 202,553 202,636 202,483 198,080

Average daily census 536 569 571 574 561

Average length of stay 7.2 7.3 7.3 7.2 7.2

Average number of inpatient beds 616 635 654 665 661

Outpatient clinic visits, treatments, procedures 1,281,489 1,338,706 1,363,008 1,440,684 1,404,329

Pathology/laboratory medicine procedures 11,619,591 11,718,405 12,005,766 12,334,917 12,073,679

Diagnostic imaging procedures 497,660 501,887 523,297 530,590 524,044

Surgery hours 66,241 70,221 69,506 69,987 67,936

Total active clinical protocols 1,078 1,065 1,101 1,197 1,202

Workforce

21,119 1,711 953 2,146 total employees faculty onsite trained offsite volunteers myCancerConnection trained survivor volunteers

MD Anderson provided more than $287.3 million in uncompensated care to Texans with cancer in FY16.*

*This figure includes unreimbursed costs of care for patients who either have no insurance or are underinsured, or whose care was not fully covered by 121,356 government-sponsored health programs. volunteer hours

70 DATA

Total philanthropic gift support by type

Cash gifts Amount

Corporations $11,248,710

Foundations 33,921,440

Individuals 61,162,580

Organizations 3,716,324

Trusts and estates 7,838,4 49

Subtotal $117,887,503

Pledge gifts

Corporations $13,586,781

Foundations 42,853,552 Total philanthropic gift support by purpose (in millions) Individuals 45,965,177

Organizations 18,605,370 $267.6 | Research2 | 91.0% Trusts and estates 54,896,801

Subtotal $175,907,681

Gifts-in-kind

Corporations $216,271

Foundations 1,771

Individuals 18,396

Organizations 6

Subtotal $236,444

$14.7 | Annual/unrestricted/ TOTAL $294,031,628 undesignated 1 | 5.0% $11.8 | Education/prevention/ patient assistance | 4.0%

1 These dollars fund institutional peer-reviewed research. 2 Donor-targeted gifts to research conducted in all mission areas.

71 MD Anderson Annual Report

Sources of research expenditures FY 2012 FY 2013 FY 2014 FY 2015 FY 2016 External funding for research

Federal grants, contracts $196,753,104 $182,970,502 $158,986,303 $161,170,908 $155,043,499

Private industry grants, contracts 68,413,794 65,579,036 75,307,463 81,076,353 89,454,454

Philanthropy, foundations 100,794,491 101,642,898 147,016,586 172,412,727 166,374,314

Total external funding $365,961,389 $350,192,436 $381,310,352 $414,659,988 $410,872,268

State funding allocated for research

State-appropriated general revenue $11,618,126 $11,776,785 $13,636,669 $13,658,113 $14,991,640

Tobacco settlement receipts 8,854,774 5,837,249 11,175,016 10,227,690 12,188,092

CPRIT 19,546,278 24,262,525 25,072,890 32,049,453 40,227,040

Total state funding $40,019,178 $41,876,559 $49,884,575 $55,935,256 $67,406,772

Internal funding allocated for research

Hospital operating margins $215,527,886 $182,770,342 202,607,346 198,607,568 193,071,901

Institutional grants* 26,032,444 95,730,271 102,391,157 111,374,655 115,938,206

Total internal funding $241,560,330 $278,500,613 $304,998,503 $309,982,223 $309,010,107

TOTAL RESEARCH EXPENDITURES $647,540,897 $670,569,608 $736,193,430 $780,577,467 $787,289,147

Education profile

FY 2012 FY 2013 FY 2014 FY 2015 FY 2016

Clinical residents, fellows 1,187 1,231 1,276 1,507 1,693

Research trainees 1,714 1,743 1,853 1,890 1,847

Observers, visitors, special programs 431 507 452 752 838

Nursing trainees 2,531 1,306* 1,238 1,352 1,499

Student programs participants 1,317 1,396 1,204 817 810

School of Health Professions students 316 291 318 303 317

TOTAL TRAINEES 7,496 6,474 6,341 6,621 7,004

*Total includes academic credit clinical placement only. Previous data included outreach and CPRIT education programs.

72 THE UNIVERSITYTHE UNIVERSITY OF TEXAS OF TEXAS SYSTEM SYSTEM BOARD BOARD OF REGENTS OF REGENTS

® ® Paul PaulL. Foster, L. Foster, El Paso El Paso ChairmanChairman In honorIn honor of Charlesof Charles Aubrey Aubrey “Mickey” “Mickey” LeMaistre, LeMaistre, M.D. M.D. 7575 years years of of Making Making Cancer Cancer History History R. StevenR. Steven Hicks, Hicks, Austin Austin Vice chairmanVice chairman Feb.Feb. 10, 192410, 1924 – Jan. – Jan. 28, 201728, 2017 CharlesCharles LaMaistre, LaMaistre, M.D., M.D., was thewas second the second full-time full-time president president of of JefferyJeffery D. Hildebrand, D. Hildebrand, Houston Houston Vice chairmanVice chairman The UniversityThe University of Texas of Texas MD AndersonMD Anderson Cancer Cancer Center, Center, serving serving ErnestErnest Aliseda, Aliseda, McAllen McAllen for 18for years, 18 years, from from 1978-1996. 1978-1996. Before Before taking taking the reins the reins from from DavidDavid J. Beck, J. Beck, Houston Houston R. LeeR. Clark, Lee Clark, M.D., M.D., LeMaistre LeMaistre spent spent seven seven years years as chancellor as chancellor of of The UniversityThe University of Texas of Texas System. System. KevinKevin Paul Eltife,Paul Eltife, Tyler Tyler MissionMission JanieceJaniece M. Longoria, M. Longoria, Houston Houston A pioneeringA pioneering figure figure in cancer in cancer prevention, prevention, LeMaistre LeMaistre served served on on the firstthe U.S. first Surgeon U.S. Surgeon General’s General’s Advisory Advisory Committee Committee on Smoking on Smoking The Themission mission of The of TheUniversity University of Texas of Texas MD MDAnderson Anderson Cancer Cancer Sara MartinezSara Martinez Tucker, Tucker, Dallas Dallas JamesJames Conrad Conrad Weaver, Weaver, San Antonio San Antonio and Health,and Health, which which in 1964 in 1964issued issued its landmark its landmark report report identifying identifying CenterCenter is to iseliminate to eliminate cancer cancer in Texas, in Texas, the nationthe nation and andthe the cigarettescigarettes as a major as a major health health hazard. hazard. worldworld through through outstanding outstanding programs programs that thatintegrate integrate patient patient VarunVarun P. Joseph, P. Joseph, McKinney McKinney care,care, research research and andprevention, prevention, and andthrough through education education for for StudentStudent regent regent UnderUnder his leadership, his leadership, MD MDAnderson’s Anderson’s prevention prevention program program undergraduateundergraduate and andgraduate graduate students, students, trainees, trainees, FrancieFrancie A. Frederick A. Frederick becamebecame an international an international model model of research of research and service and service initiatives initiatives professionals,professionals, employees employees and theand public.the public. GeneralGeneral counsel counsel to the to Board the Board of Regents of Regents that advancedthat advanced the science the science and applicationand application of cancer of cancer prevention prevention and populationand population sciences. sciences. He also He pioneered also pioneered multidisciplinary multidisciplinary care. care. THE UNIVERSITYTHE UNIVERSITY OF TEXAS OF TEXAS SYSTEM SYSTEM ADMINISTRATION ADMINISTRATION “Mickey’s“Mickey’s passing passing causes causes us to us pause to pause and andremember remember his his VisionVision WilliamWilliam H. McRaven H. McRaven tremendoustremendous contributions contributions to the to growththe growth and andscope scope of of ChancellorChancellor MD Anderson,”MD Anderson,” says Johnsays JohnMendelsohn, Mendelsohn, M.D., M.D., MD Anderson’sMD Anderson’s We shallWe shall be the be premierthe premier cancer cancer center center in the in world,the world, RaymondRaymond S. Greenberg, S. Greenberg, M.D., M.D., Ph.D Ph.D thirdthird full-time full-time president president and directorand director of the of Khalifa the Khalifa Institute Institute basedbased on the on excellencethe excellence of our of people,our people, our our for Personalizedfor Personalized Cancer Cancer Therapy. Therapy. “MD “MD Anderson Anderson experienced experienced research-drivenresearch-driven patient patient care careand andour science.our science. ExecutiveExecutive vice chancellor vice chancellor for Health for Health Affairs Affairs happyhappy and productive and productive years years under under Mickey’s Mickey’s leadership, leadership, and I and was I was fortunatefortunate to have to havethe privilege the privilege of building of building upon upon his legacy his legacy when when We areWe Makingare Making Cancer Cancer History History®. ®. I succeededI succeeded him ashim president as president in 1996.” in 1996.” LOCATIONSLOCATIONS MD AndersonMD Anderson has Houston-area has Houston-area locations locations in the in Texas the Texas Medical Medical CoreCore values values Center,Center, Bay Area, Bay Area, Katy, Katy,Sugar Sugar Land, Land, The Woodlands, The Woodlands, Bellaire Bellaire and and West WestHouston Houston (diagnostic (diagnostic imaging), imaging), Memorial Memorial City (surgery)City (surgery) and The and The CaringCaring Woman’sWoman’s Hospital Hospital of Texas of Texas (gynecologic (gynecologic oncology). oncology). MD Anderson MD Anderson EDITOREDITOR By ourBy wordsour words and andactions, actions, we createwe create a a physiciansphysicians also provide also provide cancer cancer care to care Harris to Harris County’s County’s underserved underserved AndyAndy Olin, Olin,program program director, director, Public Public Relations Relations caringcaring environment environment for everyone. for everyone. patientspatients at Lyndon at Lyndon B. Johnson B. Johnson Hospital. Hospital. In addition, In addition, there thereare two are two researchresearch campuses campuses in Bastrop in Bastrop County, County, Texas. Texas. The institution The institution also has also has developeddeveloped a network a network of national of national and international and international locations. locations. DESIGNERDESIGNER IntegrityIntegrity MichaelMichael Clarke Clarke We workWe work together together to merit to merit the trustthe trust of of ® ® our colleaguesour colleagues and andthose those we serve.we serve. MD ANDERSONMD ANDERSON CANCER CANCER NETWORK NETWORK www.mdanderson.org/cancernetworkwww.mdanderson.org/cancernetwork

DiscoveryDiscovery PARTNERPARTNER MEMBERS MEMBERS We embraceWe embrace creativity creativity and andseek seek new new knowledge. knowledge. • Banner• Banner MD Anderson MD Anderson Cancer Cancer Center Center (Gilbert, (Gilbert, Arizona) Arizona) ConquestConquest is published is published by the by MD the Anderson MD Anderson Cancer Cancer Center Center Board Board of Visitors of Visitors on behalfon behalf of MD of Anderson. MD Anderson. • MD• Anderson MD Anderson Cancer Cancer Center Center at Cooper at Cooper (Camden, (Camden, New Jersey)New Jersey) All correspondenceAll correspondence should should be addressed be addressed to the to Public the Public Relations Relations Office Office – – • Summit• Summit Medical Medical Group Group MD Anderson MD Anderson Cancer Cancer Center Center (Berkeley (Berkeley Heights, Heights, New Jersey)New Jersey) Unit 700,Unit MD 700, Anderson MD Anderson Cancer Cancer Center, Center, 6900 Fannin6900 Fannin St., Houston, St., Houston, Texas Texas 77030-3800, 77030-3800, • Baptist• Baptist MD Anderson MD Anderson Cancer Cancer Center Center (Jacksonville, (Jacksonville, Florida) Florida) 713-792-3457.713-792-3457. Email:Email: [email protected]. [email protected]. • Scripps• Scripps MD Anderson MD Anderson Cancer Cancer Center Center (San Diego,(San Diego, Calif.) Calif.) ArticlesArticles and photos and photos may be may reprinted be reprinted with permission.with permission. CERTIFIEDCERTIFIED MEMBERS MEMBERS • 15 health• 15 health systems systems and hospitals and hospitals in 12 instates 12 states For informationFor information on supporting on supporting programs programs at MD at Anderson, MD Anderson, please please contact contact ASSOCIATEASSOCIATE MEMBERS MEMBERS PatrickPatrick Mulvey, Mulvey, vice president, vice president, Development, Development, 713-792-3450, 713-792-3450, or visit or the visit the myGivingmyGiving website website at www.mdanderson.org/WinterConquest. at www.mdanderson.org/WinterConquest. • Hospital• Hospital Israelita Israelita Albert Albert Einstein Einstein (São Paulo)(São Paulo) • MD• Anderson MD Anderson Cancer Cancer Center Center Madrid Madrid For informationFor information on patient on patient services services at MD at Anderson, MD Anderson, call call askMDAndersonaskMDAnderson at 877-632-6789, at 877-632-6789, or log or on log on •Vehbi•Vehbi Koc Foundation Koc Foundation American American Hospital Hospital (Istanbul) (Istanbul) to www.mdanderson.org/ask.to www.mdanderson.org/ask. AFFILIATEAFFILIATE MEMBERS MEMBERS • MD• Anderson MD Anderson Radiation Radiation Treatment Treatment Center Center at American at American Hospital Hospital (Istanbul) (Istanbul) © 2016© The 2016 University The University of Texas of TexasMD Anderson MD Anderson Cancer Cancer Center Center Not printedNot printed at state at expense. state expense. Printed Printed with soy-based with soy-based ink. ink. • Presbyterian• Presbyterian MD Anderson MD Anderson Radiation Radiation Treatment Treatment Center Center (Albuquerque, (Albuquerque, New Mexico)New Mexico) p53 genetics research genomics education prevention patient care patient survivorship clinical trials biochemistry neuroscience palliative care nanomedicine proton therapy global outreach nanotechnology molecular biology drug development genetic counseling cancer epigenetics integrative medicine translational research chromatin remodelers germline mutagenesis cancer care innovation cytogenetic technology stem cell transplantation molecular carcinogenesis experimental therapeutics gene expression research health disparities research clinical and translational research annual report 75 years75 of patient care research prevention education history cancer making

The University of Texas MD Anderson Cancer Center Annual Report 2016