PLOS NEGLECTED TROPICAL DISEASES RESEARCH ARTICLE Spatiotemporal variability in dengue transmission intensity in Jakarta, Indonesia 1 1 1 2 Megan O'DriscollID *, Natsuko Imai , Neil M. Ferguson , Sri Rezeki Hadinegoro , Hindra Irawan Satari2, Clarence C. Tam3,4, Ilaria Dorigatti1 1 MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom, 2 Department of Child Health, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, 3 Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, 4 London School of Hygiene & Tropical Medicine, London, United Kingdom a1111111111 a1111111111 *
[email protected] a1111111111 a1111111111 a1111111111 Abstract Background OPEN ACCESS Approximately 70% of the global burden of dengue disease occurs on the Asian continent, Citation: O'Driscoll M, Imai N, Ferguson NM, where many large urban centres provide optimal environments for sustained endemic trans- Hadinegoro SR, Satari HI, Tam CC, et al. (2020) mission and periodic epidemic cycles. Jakarta, the capital of Indonesia, is a densely popu- Spatiotemporal variability in dengue transmission lated megacity with hyperendemic dengue transmission. Characterization of the intensity in Jakarta, Indonesia. PLoS Negl Trop Dis spatiotemporal distribution of dengue transmission intensity is of key importance for optimal 14(3): e0008102. https://doi.org/10.1371/journal. pntd.0008102 implementation of novel