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HRS2017 Programme Book Food and Health Bureau The Government of the Hong Kong Special Administrative Region 16 June 2017 Creating Knowledge in Complex System for Sustainable Community Health Health and Medical Research Fund Health Research Symposium 2017 Creating Knowledge in Complex System for Sustainable Community Healt Programme 08:30 – 09:00 Registration 09:00 – 09:20 Welcoming Remarks Dr KO Wing-man, BBS, JP, Secretary for Food and Health 09:20 – 10:20 Keynote Lectures Moderator: Prof Gabriel Matthew LEUNG, GBS, JP, Research Council Research on Noncommunicable Diseases Dr Douglas William BETTCHER, MD, MPH, PhD (Econ) Director, Prevention of Noncommunicable Diseases, World Health Organization Systematic Development and Evaluation of Complex Interventions to Improve Health: A Route to Success? Prof Sally WYKE, PhD, FRCGP (Hon), FRSE Deputy Director, Institute of Health and Wellbeing, The University of Glasgow Question & Answer Session 10:20 – 10:50 Tea Break / Poster Session 10:50 – 12:25 Parallel Session 1 – Health and Health Services Parallel Session 2 – Advanced Medical Research Moderator: Prof YEOH Eng-kiong, GBS, JP, Moderator: Prof LAU Yu-lung, Research Council Research Council S1 - In-depth Cost-efectiveness Study of the Multidisciplinary Risk S5 - Autonomic Dysfunction as Measured by Ewing's Battery Test to Predict Factor Assessment and Management Programme (RAMP) of the Hospital Poor Outcome after Acute Ischemic Stroke Authority Dr XIONG Li Dr Colman FUNG Siu-cheung The Chinese University of Hong Kong The University of Hong Kong S6 – Uncovering Resistant Genes in EGFR-mutated Lung Adenocarcinomas S2 - Sustainability of Treatment Efect of a 3-year Early Intervention Prior to Targeted Therapy Programme for First-episode Psychosis in Hong Kong Dr Maria WONG Pik Dr CHANG Wing-chung The University of Hong Kong The University of Hong Kong S7 - Persistence of Ciguatera Fish Poisoning and its Associated S3 - Lifestyle Intervention in Obese Chinese Adolescents with Nonalcoholic Neurological Manifestations in Mice Fatty Liver Disease: A Randomized Controlled Study Dr Eddie MA Chi-him Dr Dorothy CHAN Fung-ying City University of Hong Kong The Chinese University of Hong Kong S8 - Uncovering the Genetic Lesions Underlying the Most Severe Form of S4 - Chinese Herbal Medicine (MaZiRenWan) for Functional Constipation: Hirschsprung (HSCR) Disease by Whole Genome Sequencing (WGS): A Pilot A Prospective, Double-blinded, Double-dummy, Randomized, Controlled Study in 8 Family Trios Study Dr GARCIA-BARCELO Maria-Mercè Prof BIAN Zhao-xiang The University of Hong Kong Hong Kong Baptist University Question & Answer Session Question & Answer Session 12:25 – 13:35 Lunch Break / Poster Session 13:35 – 15:10 Parallel Session 3 – Health Promotion Parallel Session 4 – Infectious Diseases Moderator: Dr Felix CHAN Hon-wai, JP, Moderator: Prof YUEN Kwok-yung, SBS, JP, Grant Review Board, Promotion Sub-committee Grant Review Board S9 - Promotion and Brief Intervention of Smoking Cessation at the S13 – Efcacy of Combined Infuenza and 23-valent Pneumococcal Smoking Hotspots Polysaccharide Vaccines in Patients with Chronic Illness Prof LAM Tai-hing, BBS, JP Prof Ivan HUNG Fan-ngai The University of Hong Kong The University of Hong Kong S10 –“WE WRAP”: An Innovative Empowerment and Education Program S14 – Human Parechovirus Infection in Hong Kong Neonates, Infants and for People with Mental Health Challenge and Young People Young Children Ms Sania YAU Sau-wai, JP Prof Paul CHAN Kay-sheung New Life Psychiatric Rehabilitation Association The Chinese University of Hong Kong S11 - A Geographical Study of Child Injury in Hong Kong: Spatial Variation S15 - Evaluating the Health Economics of Routine Female Adolescent HPV among 18 Districts Vaccination for Reducing the Burden of Cervical Cancer in Hong Kong Mr Wilfred WONG Hing-sang Dr Joseph WU Tsz-kei The University of Hong Kong The University of Hong Kong S12 - Every Women Counts - Cancer Prevention amongst Ethnic Minority S16 - Modelling the Impacts of PrEP Intervention on the HIV Epidemic in Women MSM in Hong Kong Ms Sharmila GURUNG Dr WONG Ngai-sze United Christian Nethersole Community Health Service The Chinese University of Hong Kong Question & Answer Session Question & Answer Session 15:10 – 15:40 Tea Break / Poster Session 15:40 – 17:10 Keynote Lectures Moderator: Prof Francis CHAN Ka-leung, JP, Research Council Big Data in Health and Medicine: Issues and Challenges Prof Louisa JORM, PhD Director, Centre for Big Data Research in Health, The University of New South Wales What is mPossible? Leveraging Mobile Technology for Community Health and Global Health Systems Dr Alain Bernard LABRIQUE, PhD, MHS, MS Director, Johns Hopkins University Global mHealth Initiative Question & Answer Session 17:10 – 17:35 Award Ceremony & Closing Remarks Mr Patrick NIP Tak-kuen, JP, Permanent Secretary for Food and Health (Health) Prof Sophia CHAN Siu-chee, JP, Under Secretary for Food and Health Venue: Hong Kong Academy of Medicine Jockey Club Building, 99 Wong Chuk Hang Road, Aberdeen, Hong Kong Run Run Shaw Hall (1/F) Lim Por Yen Lecture Theatre (G/F) Pao Yue Kong Auditorium (G/F) Table of Contents Message from the Secretary for Food and Health 2 Message from the Permanent Secretary for Food and Health (Health) 3 Organising Committee of the Health Research Symposium 2017 4 Awards 5 Keynote Lectures 6 Parallel Sessions 10 Abstracts of Poster Presentations 26 About Health and Medical Research Fund 113 Venue Floor Plan 114 Message from the Secretary for Food and Health I wish you all a warm welcome to the Health Research Symposium 2017 which also commemorates the 20th anniversary of the establishment of the Hong Kong Special Administrative Region (SAR). The Health Research Symposium provides a platform to facilitate dialogue and discussion amongst our many local researchers on their latest achievements in health-related research. It aims at setting a benchmark for excellent research in health and medicine and fostering collaboration in research to improve the health of the population. It also highlights the synergy created by merging the Health and Medical Research Fund (HMRF) with the Health Care and Promotion Fund which took effect earlier this year. Such consolidated framework helps translate new knowledge into evidence-based practices which promote population health. Practitioners of health promotion will also benefit from access to greater funding and increased collaboration with expertise in academia and the public health sector. The theme of this year’s Symposium is “Creating Knowledge in Complex System for Sustainable Community Health”. Under this forward-looking theme, the Symposium focuses on evidence-based interventions at molecular, individual and system levels which integrate Big Data analysis and Mobile Health (mHealth) to address important issues of effectiveness and efficiency of our health sector. The impact of non- communicable diseases has become increasingly apparent due to our ageing population. The research topics presented today could address some of the key issues and explore interventions with potential to improve the health outcomes of the community. Over the years, the Food and Health Bureau has provided funding support for investigator-initiated and commissioned research projects, as well as a number of research fellowships under the HMRF. Together, these researches have expanded the local evidence base, built capacity in terms of research expertise and infrastructure and generated important findings for clinical practices. The Hong Kong SAR Government will continue to strive to apply the findings from locally generated research to improve health policy and practice for the benefit of everyone in Hong Kong. I would like to express my gratitude to the renowned overseas speakers and our many local experts for participating in the Symposium and sharing their knowledge and experiences with us. I wish the Symposium a great success and you all a most stimulating and rewarding occasion. Dr KO Wing-man, BBS, JP Secretary for Food and Health The Government of the Hong Kong Special Administrative Region 2 Message from the Permanent Secretary for Food and Health (Health) I am delighted to welcome our distinguished speakers and all participants to the Health Research Symposium 2017. The Government is committed to building a healthy society for all and health and medical research plays an important role by informing our health policies with the latest knowledge and most advanced development in the field. Since the last Health Research Symposium in 2014, the Government has injected a further $1,500 million into the Health and Medical Research Fund (HMRF) to ensure its continued operation to 2021/22. Apart from investigator-initiated research conducted by local researchers who are guided by the Fund’s thematic priorities, the Government has also commissioned a series of studies on a wide range of health issues to fill knowledge gaps, inform healthcare policy and practice and to address public health needs and threats. Overall, the HMRF has supported 1,396 investigator-initiated projects worth $1,078 million and 20 portfolios of commissioned programmes worth $433 million. Ongoing commissioned studies address a wide range of health issues of local relevance including screening strategies for colorectal and breast cancer, effective models to integrate health and social care services for the elderly, emerging and re-emerging infectious diseases, capacity building in Phase 1 clinical trials, and projection of healthcare manpower
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