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4/23/2015 1 •Psychedelics Or Hallucinogens
4/23/2015 Hallucinogens •Psychedelics or This “classic” hallucinogen column The 2 groups below are quite different produce similar effects From the classic hallucinogens Hallucinogens Drugs Stimulating 5HT Receptors Drugs BLOCKING ACH Receptors • aka “psychotomimetics” LSD Nightshade(Datura) Psilocybin Mushrooms Jimsonweed Morning Glory Seeds Atropine Dimethyltryptamine Scopolamine What do the very mixed group of hallucinogens found around the world share in common? •Drugs Resembling NE Drugs BLOCKING Glutamate Receptors •Peyote cactus Phencyclidine (PCP) •Mescaline Ketamine All contain something that resembles a •Methylated amphetamines like MDMA High dose dextromethorphan •Nutmeg neurotransmitter •New synthetic variations (“bath salts”) •5HT-Like Hallucinogens •LSD History • Serotonin • created by Albert Hofmann for Sandoz Pharmaceuticals LSD • was studying vasoconstriction produced by ergot alkaloids LSD • initial exposure was accidental absorption thru skin • so potent ED is in millionths of a gram (25-250 micrograms) & must be delivered on something else (sugar cube, gelatin square, paper) Psilocybin Activate 5HT2 receptors , especially in prefrontal cortex and limbic areas, but is not readily metabolized •Characteristics of LSD & Other “Typical” •Common Effects Hallucinogens • Sensory distortions (color, size, shape, movement), • Autonomic (mostly sympathetic) changes occur first constantly changing (relatively mild) • Vivid closed eye imagery • Sensory/perceptual changes follow • Synesthesia (crossing of senses – e.g. hearing music -
Hallucinogens - LSD, Peyote, Psilocybin, and PCP
Information for Behavioral Health Providers in Primary Care Hallucinogens - LSD, Peyote, Psilocybin, and PCP What are Hallucinogens? Hallucinogenic compounds found in some plants and mushrooms (or their extracts) have been used— mostly during religious rituals—for centuries. Almost all hallucinogens contain nitrogen and are classified as alkaloids. Many hallucinogens have chemical structures similar to those of natural neurotransmitters (e.g., acetylcholine-, serotonin-, or catecholamine-like). While the exact mechanisms by which hallucinogens exert their effects remain unclear, research suggests that these drugs work, at least partially, by temporarily interfering with neurotransmitter action or by binding to their receptor sites. This InfoFacts will discuss four common types of hallucinogens: LSD (d-lysergic acid diethylamide) is one of the most potent mood-changing chemicals. It was discovered in 1938 and is manufactured from lysergic acid, which is found in ergot, a fungus that grows on rye and other grains. Peyote is a small, spineless cactus in which the principal active ingredient is mescaline. This plant has been used by natives in northern Mexico and the southwestern United States as a part of religious ceremonies. Mescaline can also be produced through chemical synthesis. Psilocybin (4-phosphoryloxy-N, N-dimethyltryptamine) is obtained from certain types of mushrooms that are indigenous to tropical and subtropical regions of South America, Mexico, and the United States. These mushrooms typically contain less than 0.5 percent psilocybin plus trace amounts of psilocin, another hallucinogenic substance. PCP (phencyclidine) was developed in the 1950s as an intravenous anesthetic. Its use has since been discontinued due to serious adverse effects. How Are Hallucinogens Abused? The very same characteristics that led to the incorporation of hallucinogens into ritualistic or spiritual traditions have also led to their propagation as drugs of abuse. -
Erowid Extracts — Number 13 / November 2007 Erowid Extracts Table of Contents Number 13, November 2007
Erowid® Extracts D OCUMENTING THE C OMPLEX R ELATIONSHIP B ETWEEN H UMANS AN D P SYCHOACTIVES November 2007 Number 13 “The problem to be faced is: how to combine loyalty to one’s own tradition with reverence for different traditions.” — Abraham J. Heschel The Absinthe Enigma • Wormwood and Thujone • P. viridis vs. M. tenuiflora Varieties of Nicotine Experience • Khat Legal Challenges LETTERS & FEEDBACK Hi there Erowid staff, First of all, thank you for such Awesome website! A more thoughtfully a wonderful site. I’m not a serious compiled compendium of information I’m just writing to say how much I recreational user, but having some on the topic of psychoactives does appreciate your website. My father chronic pain issues, I tend to experiment not exist—at least not for the public showed it to me several years ago a little to find ways to alleviate the at large. Bravo. and it’s been fun to watch it grow pain (aside from standard Rx’s from in quality and content over the — ANOnymOus doctors). […] years. My dad adjunctly teaches a Letter to Erowid psychopharmacology class in town and Keep up the good work. Although always lists Erowid on his syllabus of some might look at Erowid negatively, recommended readings. I’m a college I look at it positively, in the sense that After looking up information on the student and am surprised, once I I’m smart enough to research things antitussive properties of DXM, how start talking to other kids, how many before I try them, and hopefully keep shocked I was to find your website, of them know about the information myself from an early demise. -
JONATHAN OTT SPEAKS… PART TWO Interviewed by Will Beifuss and Jon Hanna at the 1998 BPC Salvia Divinorum Conference
VOLUME VIII, NUMBER 2 SUMMER SOLSTICE 1999 JONATHAN OTT SPEAKS… PART TWO Interviewed by Will Beifuss and Jon Hanna at the 1998 BPC Salvia divinorum Conference Jon: Living in México, what do you think that the interest in at home and make tea.” But if I do that in the U.S. I know for entheogens is there, given in a sort of comparative percent- a fact that there are going to be at least a dozen people there age? that have done it more than I have, and perhaps can teach me a thing or two if I can just connect with them afterwards Jonathan: Of course we have, at best, only soft figures in any and share information. And so the U.S. is a real leader there, case. But I would say that it’s less than it is in the U.S., in and I would say in México it’s a great deal less. But on the terms of the kind of interest that we know about—basement other hand, there’s this schizophrenic thing; on the one hand shaman. In the U.S. there’s a great deal of sophistication in there’s racism against Indians and there’s this whole socio- the so-called amateur sector. And that doesn’t exist any- economic one-upmanship, but on the other hand, all of where else, not even in Europe. In Europe, the only people México’s glory lies in the pre-Colombian past, and it’s been that are at that level of sophistication are in the business as all downhill—and very steeply—politically and economi- shamanic-plant dealers, and they’re very few. -
Psilocybin Mushrooms Fact Sheet
Psilocybin Mushrooms Fact Sheet January 2017 What are psilocybin, or “magic,” mushrooms? For the next two decades thousands of doses of psilocybin were administered in clinical experiments. Psilocybin is the main ingredient found in several types Psychiatrists, scientists and mental health of psychoactive mushrooms, making it perhaps the professionals considered psychedelics like psilocybin i best-known naturally-occurring psychedelic drug. to be promising treatments as an aid to therapy for a Although psilocybin is considered active at doses broad range of psychiatric diagnoses, including around 3-4 mg, a common dose used in clinical alcoholism, schizophrenia, autism spectrum disorders, ii,iii,iv research settings ranges from 14-30 mg. Its obsessive-compulsive disorder, and depression.xiii effects on the brain are attributed to its active Many more people were also introduced to psilocybin metabolite, psilocin. Psilocybin is most commonly mushrooms and other psychedelics as part of various found in wild or homegrown mushrooms and sold religious or spiritual practices, for mental and either fresh or dried. The most popular species of emotional exploration, or to enhance wellness and psilocybin mushrooms is Psilocybe cubensis, which is creativity.xiv usually taken orally either by eating dried caps and stems or steeped in hot water and drunk as a tea, with Despite this long history and ongoing research into its v a common dose around 1-2.5 grams. therapeutic and medical benefits,xv since 1970 psilocybin and psilocin have been listed in Schedule I of the Controlled Substances Act, the most heavily Scientists and mental health professionals criminalized category for drugs considered to have a consider psychedelics like psilocybin to be “high potential for abuse” and no currently accepted promising treatments as an aid to therapy for a medical use – though when it comes to psilocybin broad range of psychiatric diagnoses. -
Near the Himalayas, from Kashmir to Sikkim, at Altitudes the Catholic Inquisition, and the Traditional Use of These of up to 2700 Meters
Year of edition: 2018 Authors of the text: Marc Aixalà & José Carlos Bouso Edition: Alex Verdaguer | Genís Oña | Kiko Castellanos Illustrations: Alba Teixidor EU Project: New Approaches in Harm Reduction Policies and Practices (NAHRPP) Special thanks to collaborators Alejandro Ponce (in Peyote report) and Eduardo Carchedi (in Kambó report). TECHNICAL REPORT ON PSYCHOACTIVE ETHNOBOTANICALS Volumes I - II - III ICEERS International Center for Ethnobotanical Education Research and Service INDEX SALVIA DIVINORUM 7 AMANITA MUSCARIA 13 DATURA STRAMONIUM 19 KRATOM 23 PEYOTE 29 BUFO ALVARIUS 37 PSILOCYBIN MUSHROOMS 43 IPOMOEA VIOLACEA 51 AYAHUASCA 57 IBOGA 67 KAMBÓ 73 SAN PEDRO 79 6 SALVIA DIVINORUM SALVIA DIVINORUM The effects of the Hierba Pastora have been used by Mazatec Indians since ancient times to treat diseases and for divinatory purposes. The psychoactive compound Salvia divinorum contains, Salvinorin A, is the most potent naturally occurring psychoactive substance known. BASIC INFO Ska Pastora has been used in divination and healing Salvia divinorum is a perennial plant native to the Maza- rituals, similar to psilocybin mushrooms. Maria Sabina tec areas of the Sierra Madre Oriental Mountains of Mexi- told Wasson and Hofmann (the discoverers of its Mazatec co. Its habitat is tropical forests, where it grows between usage) that Salvia divinorum was used in times when the- 300 and 800 meters above sea level. It belongs to the re was a shortage of mushrooms. Some sources that have Lamiaceae family, and is mainly reproduced by cuttings done later feldwork point out that the use of S. divinorum since it rarely produces seeds. may be more widespread than originally believed, even in times when mushrooms were abundant. -
Mycological Investigations on Teonanacatl the Mexican Hallucinogenic Mushroom
Mycological investigations on Teonanacatl, the mexican hallucinogenic mushroom by Rolf Singer Part I & II Mycologia, vol. 50, 1958 © Rolf Singer original report: https://mycotek.org/index.php?attachments/mycological-investigations-on-teonanacatl-the-mexian-hallucinogenic-mushroom-part-i-pdf.511 66/ Table of Contents: Part I. The history of Teonanacatl, field work and culture work 1. History 2. Field and culture work in 1957 Acknowledgments Literature cited Part II. A taxonomic monograph of psilocybe, section caerulescentes Psilocybe sect. Caerulescentes Sing., Sydowia 2: 37. 1948. Summary or the stirpes Stirps. Cubensis Stirps. Yungensis Stirps. Mexicana Stirps. Silvatica Stirps. Cyanescens Stirps. Caerulescens Stirps. Caerulipes Key to species of section Caerulescentes Stirps Cubensis Psilocybe cubensis (Earle) Sing Psilocybe subaeruginascens Höhnel Psilocybe aerugineomaculans (Höhnel) Stirps Yungensis Psilocybe yungensis Singer and Smith Stirps Mexicana Psilocybe mexicana Heim Stirps Silvatica Psilocybe silvatica (Peck) Psilocybe pelliculosa (Smith) Stirps Cyanescens Psilocybe aztecorum Heim Psilocybe cyanescens Wakefield Psilocybe collybioides Singer and Smith Description of Maire's sterile to semi-sterile material from Algeria Description of fertile material referred to Hypholoma cyanescens by Malençon Psilocybe strictipes Singer & Smith Psilocybe baeocystis Singer and Smith soma rights re-served 1 since 27.10.2016 at http://www.en.psilosophy.info/ mycological investigations on teonanacatl the mexican hallucinogenic mushroom www.en.psilosophy.info/zzvhmwgkbubhbzcmcdakcuak Stirps Caerulescens Psilocybe aggericola Singer & Smith Psilocybe candidipes Singer & Smith Psilocybe zapotecorum Heim Stirps Caerulipes Psilocybe Muliercula Singer & Smith Psilocybe caerulipes (Peck) Sacc. Literature cited soma rights re-served 2 since 27.10.2016 at http://www.en.psilosophy.info/ mycological investigations on teonanacatl the mexican hallucinogenic mushroom www.en.psilosophy.info/zzvhmwgkbubhbzcmcdakcuak Part I. -
Chemical Composition of Traditional and Analog Ayahuasca
Journal of Psychoactive Drugs ISSN: (Print) (Online) Journal homepage: https://www.tandfonline.com/loi/ujpd20 Chemical Composition of Traditional and Analog Ayahuasca Helle Kaasik , Rita C. Z. Souza , Flávia S. Zandonadi , Luís Fernando Tófoli & Alessandra Sussulini To cite this article: Helle Kaasik , Rita C. Z. Souza , Flávia S. Zandonadi , Luís Fernando Tófoli & Alessandra Sussulini (2020): Chemical Composition of Traditional and Analog Ayahuasca, Journal of Psychoactive Drugs, DOI: 10.1080/02791072.2020.1815911 To link to this article: https://doi.org/10.1080/02791072.2020.1815911 View supplementary material Published online: 08 Sep 2020. Submit your article to this journal View related articles View Crossmark data Full Terms & Conditions of access and use can be found at https://www.tandfonline.com/action/journalInformation?journalCode=ujpd20 JOURNAL OF PSYCHOACTIVE DRUGS https://doi.org/10.1080/02791072.2020.1815911 Chemical Composition of Traditional and Analog Ayahuasca Helle Kaasik a, Rita C. Z. Souzab, Flávia S. Zandonadib, Luís Fernando Tófoli c, and Alessandra Sussulinib aSchool of Theology and Religious Studies; and Institute of Physics, University of Tartu, Tartu, Estonia; bLaboratory of Bioanalytics and Integrated Omics (LaBIOmics), Institute of Chemistry, University of Campinas (UNICAMP), Campinas, SP, Brazil; cInterdisciplinary Cooperation for Ayahuasca Research and Outreach (ICARO), School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil ABSTRACT ARTICLE HISTORY Traditional ayahuasca can be defined as a brew made from Amazonian vine Banisteriopsis caapi and Received 17 April 2020 Amazonian admixture plants. Ayahuasca is used by indigenous groups in Amazonia, as a sacrament Accepted 6 July 2020 in syncretic Brazilian religions, and in healing and spiritual ceremonies internationally. -
Toxic Fungi of Western North America
Toxic Fungi of Western North America by Thomas J. Duffy, MD Published by MykoWeb (www.mykoweb.com) March, 2008 (Web) August, 2008 (PDF) 2 Toxic Fungi of Western North America Copyright © 2008 by Thomas J. Duffy & Michael G. Wood Toxic Fungi of Western North America 3 Contents Introductory Material ........................................................................................... 7 Dedication ............................................................................................................... 7 Preface .................................................................................................................... 7 Acknowledgements ................................................................................................. 7 An Introduction to Mushrooms & Mushroom Poisoning .............................. 9 Introduction and collection of specimens .............................................................. 9 General overview of mushroom poisonings ......................................................... 10 Ecology and general anatomy of fungi ................................................................ 11 Description and habitat of Amanita phalloides and Amanita ocreata .............. 14 History of Amanita ocreata and Amanita phalloides in the West ..................... 18 The classical history of Amanita phalloides and related species ....................... 20 Mushroom poisoning case registry ...................................................................... 21 “Look-Alike” mushrooms ..................................................................................... -
Psychedelic Gospels
The Psychedelic Gospels The Psychedelic Gospels The Secret History of Hallucinogens in Christianity Jerry B. Brown, Ph.D., and Julie M. Brown, M.A. Park Street Press Rochester, Vermont • Toronto, Canada Park Street Press One Park Street Rochester, Vermont 05767 www.ParkStPress.com Park Street Press is a division of Inner Traditions International Copyright © 2016 by Jerry B. Brown and Julie M. Brown All rights reserved. No part of this book may be reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, or by any information storage and retrieval system, without permission in writing from the publisher. Note to the Reader: The information provided in this book is for educational, historical, and cultural interest only and should not be construed in any way as advocacy for the use of hallucinogens. Neither the authors nor the publishers assume any responsibility for physical, psychological, legal, or any other consequences arising from these substances. Library of Congress Cataloging-in-Publication Data [cip to come] Printed and bound in XXXXX 10 9 8 7 6 5 4 3 2 1 Text design and layout by Priscilla Baker This book was typeset in Garamond Premier Pro with Albertus and Myriad Pro used as display typefaces All Bible quotations are from the King James Bible Online. A portion of proceeds from the sale of this book will support the Multidisciplinary Association for Psychedelic Studies (MAPS). Founded in 1986, MAPS is a 501(c)(3) nonprofit research and educational organization that develops medical, legal, and cultural contexts for people to benefit from the careful uses of psychedelics and marijuana. -
In the Supreme Court of the United States
No. 04-1084 In the Supreme Court of the United States ALBERTO R. GONZALES, ATTORNEY GENERAL, ET AL., PETITIONERS v. O CENTRO ESPIRITA BENEFICIENTE UNIAO DO VEGETAL, ET AL. ON WRIT OF CERTIORARI TO THE UNITED STATES COURT OF APPEALS FOR THE TENTH CIRCUIT JOINT APPENDIX (VOLUME 1) PAUL D. CLEMENT NANCY HOLLANDER Solicitor General Freedman Boyd Daniels Department of Justice Hollander & Goldberg P.A. Washington, D.C. 20530-0001 20 First Plaza, Suite 700 (202) 514-2217 Albuquerque, NM 87102 (505) 842-9960 Counsel of Record Counsel of Record for Petitioners for Respondents PETITION FOR A WRIT OF CERTIORARI FILED: FEB. 10, 2005 CERTIORARI GRANTED: APR. 18, 2005 TABLE OF CONTENTS Page Court of appeals docket entries ........................................ 1 District court docket entries ............................................. 10 Plaintiffs’ original complaint (Nov. 21, 2000) .................. 17 Answer to plaintiffs’ original complaint (Feb. 1, 2001) ............................................................................... 37 Declaration of Jeffrey Bronfman (Nov. 17, 2000) (Plaintiffs’ Exh. A) ....................................................... 49 Human Psychopharmacology of Hoasca, etc. (Vol. 184, No. 3, 1996) (Plaintiffs’ Exh. G) ............... 75 District court order (May 31, 2001) .................................. 102 Index and mailing list of churches (Defendants’ Exh. D) ........................................................................... 105 Expert Report of Dr. Sander G. Genser (undated) (Defendants’ Exh. ZZ) -
Sacred Mushrooms of the Goddess and the Secrets of Eleusis
In memory of Blaise Daniel Staples, my companion and soul mate. He is dearly missed. PREFACE by Huston Smith WHEN I WAS ABOUT TO PUBLISH Cleansing the Doors of Perception: The Religious Significance of Entheogenic Plants and Chemicals, there were those who advised me not to do so, saying that it would destroy my reputation. Time has proved them wrong. As the religious significance of these substances comes to be increasingly accepted—the glaring exception being the Food and Drug Administration—the sales of that book (favorably reviewed from the beginning) continue to rise. As does my conviction of the importance of the issue, and I will say why. The great achievement of the linguist Noam Chomsky, who was my colleague during the fifteen years I taught at MIT, was to discover the universal grammar that every spoken language–– English, Chinese, French, whatever––must conform to, for it seems to be imprinted into the human brain. I, for my part, have worked out the universal grammar of religion to which authentic religions conform. Reduced to a single sentence, that grammar concludes that Reality is Perfect, and that human beings should do their best to conform their lives to that perfection. Reality’s perfection seems to be contradicted by perception of the world, but this is not surprising, for Reality is Infinite and our minds are not. Out minds must expand if they are to receive even glimpses of the Infinite Perfection. Thus the question is: how can they do this? Perfect Reality has provided a way. Through the entheogens, to be sure, but here we come to a point that has been under-noticed in the discussion of this important subject.