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microbiologytoday vol34|may07 quarterly magazine of the society for general microbiology actinobacteria streptomyces – not just antibiotics good, bad, but beautiful actinobacteria corynebacteria – good guys and bad guys the mycobacteria review of uk microbial science contents vol34(2) regular features 54 News 88 Gradline 96 Reviews 82 Meetings 90 Hot off the press 99 Addresses 84 Schoolzone 93 Going public other items 59 Micro shorts 94 Members’ reports 98 Obituary articles 60 An introduction to the 74 Corynebacteria: actinobacteria the good guys and the bad David Hopwood guys Pathogenic, symbiotic and industrially important, Michael Bott this group of micro-organisms is diverse and The products of this genus range from useful amino acids fascinating. used as flavour-enhancing food additives to deadly toxins that help us to understand virulence. 64 Streptomyces: not just antibiotics 78 The mycobacteria Rosemary Loria, Madhumita Joshi & Matt Hutchings Simon Moll These successful pathogens, causing diseases An alternative insight into the pathogenic ability of these such as tuberculosis and leprosy, are still a usually life-saving organisms. major threat to global health. 68 Good, bad, but 100 Comment: beautiful: the weird and Review of UK microbial wonderful actinobacteria science Paul Hoskisson Charles Dorman Morphologically complex, challenging and Microbiology plays a pivotal role in the scientific and rewarding; we have barely scratched the surface economic life of the UK. Greater interaction between when it comes to the Jekyll and Hyde microbes. funders may strengthen this position in the future. Cover image False colour image of GFP-tagged Streptomyces turgidiscabies colonizing radish seedling root hair cells. Simon Moll & Kent Loeffler The views expressed Editor Dr Matt Hutchings––Editorial Board Dr Sue Assinder, Professor Iain Hagan, Professor Bert Rima––Managing Editor Janet Hurst––Assistant Editor Lucy Goodchild by contributors are not Design & Production Ian Atherton––Contributions are always welcome and should be addressed to the Editor c/o SGM Headquarters, Marlborough House, necessarily those of the Basingstoke Road, Spencers Wood, Reading RG7 1AG–Tel. 0118 988 1809–Fax 0118 988 5656–email [email protected]–web www.sgm.ac.uk–– Society; nor can the Advertising David Lancaster, McMillan-Scott PLC, London Office, 10 Savoy Street, London WC2E 7HR–t 0207 878 2316–f 0207 379 7118–e [email protected]–– Regular feature images pp. 55 SGM; 82, 85, 97 Comstock / Jupiter Images; 89, 91 Stockbyte; 99 Digital Vision/Getty claims of advertisers © 2007 The Society for General Microbiology––ISSN 1464-0570––Printed by Latimer Trend & Company Ltd, Plymouth, UK be guaranteed. news Promoting microbiology JGV back SGM Council The longest biological A poster with a difference archive now February Meeting Highlights experiment on record? We have produced a colourful and striking poster to raise the profile of microbiology. It online! Member Dr Richard Lawes and Henry Gilbert European virology on Lawes estate, now the contains high quality images of a range of micro-organisms and some descriptive text, plus The entire back content Jackson much enjoyed Council agreed to proposals to support both the European site of Rothamsted. The the relevant contact details to obtain further information from the SGM. The poster will of JGV, from volume 1 Dr Jean Lindenmann’s Society for Clinical Virology and the European Virology most famous of these field liven up your lab wall, but is also intended for distribution to schools and colleges. issue 1 (January 1967), is contribution to the February Forum in their activities. experiments is Broadbalk, a now available free online issue of Microbiology Today Careers matters field that was divided into at HighWire at http://vir. on the serial passaging of SGM Prize Lectures strips that receive either Our factsheets to promote microbiology degree courses sgmjournals.org the rabies virus in Saigon and careers after graduation have been updated and printed Council discussed some proposed revisions of the SGM from 1891 to 1953. In no or differing fertilizer in a new format. The first set, aimed at school students, is The project involved Prize Lecture rules. They decided that self-nominations will suggesting that this must treatments. This experiment called Studying Microbiology and includes three leaflets: scanning a total of 73,378 no longer be permitted and that some existing restrictions be one of the longest was started in 1843 and is (1) Applying to university; (2) First degree courses in pages and constructing on eligibility for the Fleming Prize lecture will be removed. biological experiments on still continuing with only a microbiology & biotechnology; and (3) Vacation work. full text PDFs for 8,716 Details of the revised rules are available on the SGM record, he feels sure that few changes during its 164 The second set describes various career paths for graduates. articles. This fills the gap website. Nominations for the 2008 SGM Prize Lectures Dr Lindenmann will have years. Regular assessments Under the heading Microbiology Careers, it features (1) to January 1997, when are now invited (see p. 58). expected, and perhaps are made of such parameters Options after graduation; (2) Postdoctoral research; (3) ‘regular’ online content hoped, that the claim as crop yield, soil chemistry SGM journals The healthcare sector; (4) Moving out of the laboratory; (5) begins. Full text searching would be challenged. and microbiology. I look Writing CVs and covering letters; (6) Job interviews; and is available from the entire Council was informed of developments in scientific forward to hearing of other ‘Since I worked for 10 (7) Postdoc and beyond – aiming for a lectureship. archive. Work continues on journal publishing which it continues to monitor carefully, experiments that have years of my career as a soil mounting the back archives in particular with regard to the issue of ‘open access’. continued for more than 100 All of the factsheets are packed with useful practical microbiologist at Rothamsted of Microbiology, Journal of years.’ information and lists of further resources. You can see them Medical Microbiology and SGM finances Experimental Station, I online at www.biocareers.org.uk immediately thought of the Can any reader rise to this International Journal of Council members heard that the audit of the SGM 2006 classical field experiments challenge? If so, email Copies of these resources are available from the External Systematic and Evolutionary accounts had successfully taken place. The financial situation which were initiated by John [email protected] Relations Office. Email [email protected] Microbiology. of the Society at the end of the year was healthy. FIS Conference 2006 Federation of Infection Annual SGM’s charitable status SGM provided the organizing secretariat for the 2006 Conference of the Federation of Infection Societies (FIS), at Societies (FIS) Conference 2007 The Society has enjoyed the benefits of charitable status since the 1950s, through General the request of the British Infection Society. The conference registration with the Charity Commission for England and Wales. Historically, there was 28–30 November 2007, Cardiff City Hall Meeting took place in Cardiff in November 2006, was well attended no Scottish equivalent of the Charity Commission: charitable status north of the border and very successful. In 2007 SGM will again provide the 2007 was approved by the Inland Revenue. Recently, however, with the advent of the Scottish organizing secretariat for the FIS conference as well as The AGM of the Society Parliament and Executive, moves have been made to introduce a regulatory regime broadly acting as the host scientific society. will be held on Tuesday, similar to that in England and Wales, and in December 2003 the Office of the Scottish 4 September 2007 at Charity Regulator (OSCR) was formally launched. Since then it has been moving forward Meetings the Society Meeting at the process of registering Scottish charities. The Scientific Meetings Officer noted that the working party the University of Edinburgh. Most charities registered in England and Wales are able to have a certain level of activities to review the SGM meetings and group structure would be Agenda papers, including in Scotland without the need for registration there. However, the advice received was that meeting at the end of February to start its deliberations. It is reports from Officers the scale of SGM’s meetings in Scotland – not least because Edinburgh is a very popular hoped to make recommendations for any changes to June and Group Conveners, venue for our events – indicated that registration was required. Accordingly, an application Council. the Accounts of the This year the SGM is hosting and organizing the FIS was made to OSCR, giving full details of the Society’s objectives, activities and finances. Society for 2006 and annual meeting. The event provides a forum for clinical The application has been approved, subject to a minor amendment to one of the Society’s MP to visit to Marlborough House a Resolution to amend microbiologists and other professionals working on governing documents, the Memorandum of Association. This needs to include an additional Sue Assinder informed Council that the shadow Minister the Memorandum of infectious diseases. The varied programme includes plenary clause, to the effect that the Society’s charitable purpose is regarded as charitable both in for Energy, Science and Technology,