FSHB Monoclonal ANTIBODY Catalog Number:67131-1-Ig

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FSHB Monoclonal ANTIBODY Catalog Number:67131-1-Ig

For Research Use Only FSHB Monoclonal ANTIBODY www.ptglab.com Catalog Number:67131-1-Ig Catalog Number: GenBank Accession Number: Purification Method: Basic Information 67131-1-Ig BC113488 Protein A purification Size: GeneID (NCBI): CloneNo.: 150UL , Concentration: 1000 μg/ml by 2488 1B10A11 Bradford method using BSA as the Full Name: Recommended Dilutions: standard; follicle stimulating hormone, beta IHC 1:500-1:2000 Source: polypeptide Mouse Calculated MW: Isotype: 129 aa, 15 kDa IgG2b Immunogen Catalog Number: AG13788 Applications Tested Applications: Positive Controls: IHC, ELISA IHC : human pituitary tissue, human pituitary Species Specificity: adenoma tissue Human Note-IHC: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 The FSHB gene encodes the beta subunit of follicle-stimulating hormone (FSH), particularly expressed in Background Information gonadotroph cells within the anterior pituitary gland and plays a critical role in the regulation of gonadal function, pubertal maturation and reproductive processes in mammals. The transcription of the FSHB gene is critical for the production of the FSH hormone(PMID:28281143). And FSH is required for ovarian folliculogenesis in females, in males it promotes spermatogenesis in conjunction with testosterone(PMID:11739331). Mutations in FSHB gene would result in infertility both in men and women (PMID: 23766128). Storage: Storage Store at -20°C. Storage Buffer: PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Aliquoting is unnecessary for -20ºC storage For technical support and original validation data for this product please contact: This product is exclusively available under Proteintech T: 1 (888) 4PTGLAB (1-888-478-4522) (toll free E: [email protected] Group brand and is not available to purchase from any in USA), or 1(312) 455-8498 (outside USA) W: ptglab.com other manufacturer. Selected Validation Data Immunohistochemical analysis of paraffin- Immunohistochemical analysis of paraffin- embedded human pituitary tissue slide using embedded human pituitary tissue slide using 67131-1-Ig (FSHB antibody) at dilution of 1:1000 67131-1-Ig (FSHB antibody) at dilution of 1:1000 (under 10x lens. Heat mediated antigen retrieval (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). with Tris-EDTA buffer (pH 9.0)..

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Strategies to Increase ß-Cell Mass Expansion
This electronic thesis or dissertation has been downloaded from the King’s Research Portal at https://kclpure.kcl.ac.uk/portal/ Strategies to increase -cell mass expansion Drynda, Robert Lech Awarding institution: King's College London The copyright of this thesis rests with the author and no quotation from it or information derived from it may be published without proper acknowledgement. END USER LICENCE AGREEMENT Unless another licence is stated on the immediately following page this work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International licence. https://creativecommons.org/licenses/by-nc-nd/4.0/ You are free to copy, distribute and transmit the work Under the following conditions: Attribution: You must attribute the work in the manner specified by the author (but not in any way that suggests that they endorse you or your use of the work). Non Commercial: You may not use this work for commercial purposes. No Derivative Works - You may not alter, transform, or build upon this work. Any of these conditions can be waived if you receive permission from the author. Your fair dealings and other rights are in no way affected by the above. Take down policy If you believe that this document breaches copyright please contact [email protected] providing details, and we will remove access to the work immediately and investigate your claim. Download date: 02. Oct. 2021 Strategies to increase β-cell mass expansion A thesis submitted by Robert Drynda For the degree of Doctor of Philosophy from King’s College London Diabetes Research Group Division of Diabetes & Nutritional Sciences Faculty of Life Sciences & Medicine King’s College London 2017 Table of contents Table of contents .................................................................................................
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