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Integrating the Life Sciences from Molecule to Organism TheThe PhysiologistPhysiologist A Publication of the American Physiological Society Volume 54, No. 6 December 2011 2011 American Physiological Society Meetings Program and Abstracts Issue 20112 APS Conference: 7tht International Symposium on Aldosterone andan the ENaC/Degenerin Family of Ion Channels: MMolecular Mechanisms and Pathophysiology (September(S 2011, Pacific Grove, California) 2011 APS Conference: Physiology of Cardiovascular Disease: Gender Disparities (October 2011, Jackson, Mississippi) Fast track your research and publishing Accelerate the pace of your research with the data acquisition systems cited in more published papers*. ADInstruments PowerLab® systems are easy to use, intuitive and powerful, allowing you to start and progress research quickly. The system’s fl exibility enables you to add specialist instruments and software- controlled amplifi ers for your specifi c experiments. What’s more, LabChart® software (included with every system), offers parameters tailored to individual applications and unmatched data integrity for indisputably trustworthy data. When there’s no prize for second place, ADInstruments PowerLab systems help you to publish. First. To fi nd out more, visit adinstruments.com/publish *According to Google Scholar, ADInstruments systems are cited in over 50,000 published papers and other works of scholarly literature. USA • BRAZIL • CHILE • UK • GERMANY • INDIA • JAPAN • CHINA • MALAYSIA • NEW ZEALAND • AUSTRALIA SADI0004_APS_PowerLab_printsoni page 1.indd 1 31/03/11 3:03 PM Published by The American Physiological Society Integrating the Life Sciences from Molecule to Organism The PhysiologistPhysiologist Physiology: Evolving, Not Declining Dee U. Silverthorn Integrative Biology, Univ. of Texas INSIDE In April 2011 The Scientist maga- Physiology” is a theme that has been zine published an opinion piece by repeated many times and has been Richard Naftalin, a British physiolo- written about at regular intervals over gist, titled “The Decline of Physiology” the last 40 years (5, 8, 10, 11, 16, 28). APS Bylaw (20). Despite the foreboding title and The reality is that as research tools for accompanying photograph of a dissect- investigating physiological mecha- Changes ed grass frog, the article dealt largely nisms shifted from whole animal and p. 237 with the decline in physiology teaching tissue studies to cellular and molecu- in British medical schools: fewer lec- lar levels of organization, attention ture hours, the loss of animal-based moved away from the traditional sci- Experimental laboratory classes, and replacement of entific disciplines, and a chasm devel- Biology 2012 practical laboratories with demonstra- oped between researchers and physiol- p. 246 tions, computer-aided learning pro- ogy educators. Departments of physiol- grams and problem-based learning ogy disappeared, subsumed into (PBL) sessions that focused on human departments of basic biomedical sci- APS Promotes medicine to the exclusion of funda- ences for budgetary reasons or Physiology to mental basic science. An expanded ver- renamed, with titles such as Biology Educators sion of the article (actually the original “Molecular Physiology and Biophysics” essay, which was too long for The or “Cellular and Molecular at National Scientist) was subsequently published Physiology,” to be more attractive to Convention in Physiology News, The Physiological contemporary researchers. Even more p. 250 Society newsletter, under the title “The alarming in terms of the pipeline for decline of physiology teaching in physiologists of the future, physiology British universities” (19; R. Naftalin, began to disappear from the under- APS Conference personal communication). The two graduate biology curriculum. Reports articles were then followed by a debate Is Physiology a discipline that needs p. 253 at the July 2011 meeting of The to be preserved? In answer to the Physiological Society on the state- debate statement, “Physiology as a ment, “Physiology as a separate disci- separate discipline is no longer rele- Science Policy pline is no longer relevant to modern vant to modern science,” I would con- Members Advocate science” (24). Naftalin’s article in The tend that physiology will never be Scientist struck a chord with physiolo- irrelevant as long as there is life on for Research gists around the world, and evoked a earth. Physiology is arguably the most Funding lively discussion on the International egalitarian of the biological disci- p. 260 Union of Physiological Societies plines. It is integrative, spanning all (IUPS) Teaching listserve and a ses- levels of organization, from biochem- sion on “decline” at the September istry and cell biology to the physiolog- Brinster and Chien 2011 Federations of Asian and ical adaptations that allow species to Receive National Oceanian Physiological Societies occupy particular ecological niches. Medal of Science (FAOPS) meeting in Taiwan. Physiology embraces physics and But is Physiology really declining? mathematics and engineering and p. 262 Concern about “the future of (continued on page 238) Volume 54, No. 6 - December 2011 www.the-aps.org 233 Published bimonthly and distributed by The American Physiological TheThe Society PhysiologistPhysiologist 9650 Rockville Pike Bethesda, Maryland 20814-3991 ISSN 0031-9376 Joey P. Granger President Contents Peter D. Wagner Past President Susan M. Barman Physiology: Evolving, Not Declining Membership President-Elect Dee U. Silverthorn 233 New Regular Members 257 Martin Frank Editor and Executive Director New Undergraduate Student Institute for Integrative Members 257 Councillors Kenneth M. Baldwin, Physiology: Resurrection of New Graduate Student Members 257 David P. Brooks, Physiology at the Recently Deceased Member 257 Dennis Brown, Patricia E. Molina, Ida Llewellyn-Smith, Univ. of Chicago Usha Raj, Jane F. Reckelhoff, Nanduri R. Prabhakar 235 Science Policy Curt D. Sigmund, Alan F. Sved APS Comments on the Future Ex Officio APS News of the Biomedical Workforce 259 Pamela K. Carmines, John C. Chatham, APS Bylaw Changes 237 Science Policy Committee Thomas A. Pressley, Members Advocate for Research Hershel Raff, Jeff M. Sands Chapter News Funding 260 Tennessee Physiological Society Publications Committee: Chair: Hershel Raff; Members: Kim E. Meeting 2011 243 Mentoring Forum Barrett, William Chilian, Asrar Summer Research Programs 261 Malik, David Pollock, Helen E. Raybould, Celia Sladek. Director of Experimental Biology 2012 246 Publications: Rita Scheman. People & Places Design and Copy Editor: Joelle R. Grossnickle. Education Brinster and Chien Receive Subscriptions: Distributed to Two APS Members Awarded the 2011 National Medal of Science 262 members as part of their member- ASBMB STEM SEED Grant for Nishimura Receives Lifetime ship. Nonmembers in the USA (print only): individuals $85.00; PhUn Week Activities 248 Achievement Award 263 institutions $135.00. Nonmembers APS Leads Teachers to New APS Congratulates Garcia and in Canada: individuals $125.00; institutions $170.00. Nonmembers Physiology Frontiers in Online Hökfelt on Their IOM Election 263 elsewhere: individuals $125.00; Program 249 institutions $170.00. Single copies and back issues when available, APS Promotes Physiology to Book Review 264 $20.00 each; single copies and back Biology Educators at National issues of Abstracts issues when available, $30.00. Subscribers to Convention 250 Positions Available 265 The Physiologist also receive APS Archive of Teaching Resources abstracts of the Conferences of the American Physiological Society. Thanks its 2011 Reviewers 250 Current Calls for Papers 268 The online version is available free APS Undergraduate Summer to all worldwide. Research Fellows Wine Wizard 269 The American Physiological Society assumes no responsibility for the Finish Research 251 statements and opinions advanced Meetings & Congresses 270 by contributors to The Physiologist. APS Conferences Please notify the APS Member- ship Department as soon as 7th International Symposium on APS Membership Application 271 possible if you change your Aldosterone and the address or telephone number. ENaC/Degenerin Family of Ion APS Conference Programs 273 Headquarters phone: 301-634-7118 Fax: 301-634-7241 Channels: Molecular Mechanisms Email: [email protected] and Pathophysiology 253 http://www.the-aps.org Physiology of Cardiovascular Printed in the USA Disease: Gender Disparities 255 234 The Physiologist Resurrection of Physiology Vol. 54, No. 6, 2011 Institute for Integrative Physiology: Resurrection of Physiology at the University of Chicago Nanduri R. Prabhakar Institute for Integrative Physiology University of Chicago The University of Chicago is one of Anton Julius Carlson (“Ajax”) who a uniform potential. He used this tech- the oldest US universities founded in joined the faculty in 1904 after receiv- nique to clamp the current of neurons. 1890 by the American Baptist ing his doctorate (in physiology) from Using the idea of the space clamp, Education Society and oil magnate Stanford. Carlson was the Chair of the Kenneth S. Cole introduced the voltage John D. Rockefeller. The first president department from 1916 to 1940. Carlson clamp to the world, which was used William Rainey Harper, hoped for a had an impact on a variety of different soon afterwards by Hodgkin and university that combined an American- areas of physiology. He was undoubted- Huxley in their pioneering work. Both style undergraduate liberal arts college ly one of the preeminent
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