RECENT ADVANCES IN THE TRIBOLOGY AND BIOENGINEERING OF THE SKIN
25 November 2014 Tribology Group and Biomedical One Birdcage Walk, London Division www.imeche.org/events/S6128 Seminar RECENT ADVANCES IN THE TRIBOLOGY AND BIOENGINEERING OF THE SKIN 25 November 2014, One Birdcage Walk, London
RECENT ADVANCES IN THE TRIBOLOGY AND BIOENGINEERING BENEFITS OF ATTENDANCE: OF THE SKIN WILL PRESENT CUTTING EDGE SOLUTIONS AND • Analyse how modelling techniques are RADICAL NEW THINKING THAT used to elucidate the complex mechanics CHARACTERISE AND PREDICT of the skin with Dr. Georges Limbert THE BIOPHYSICS OF THE SKIN IN HEALTH AND DISEASE. • Understand how microclimate factors influence the integrity of the loaded skin This seminar will explore modelling techniques interface with Prof. Dan Bader for biotribology, including the latest advanced computational models for skin biophysics. • Learn how to tackle current challenges The principal goal is to explore how they in healthcare and personal care device are developed and can be implemented in development with Dr. Steve Franklin commercial, finite element codes to accelerate product development. • Study the prospects of consultant engineers in the high-growth ‘engineering for life sciences’ market
AGENDA SNAPSHOT: (For the full programme, see page 2) • Predictive modelling of the static and dynamic friction behaviour of human skin • Biotribology: challenges in healthcare and personal care device development • Evaluation of the impact of sun exposure on the skin barrier using a biomechanics framework • Mechanical properties of the top-layers of human skin
SPONSORSHIP & EXHIBITION OPPORTUNITIES GET INVOLVED Attending this event as either an exhibitor or sponsor will give you the opportunity to display your solutions, services and products to the right people at the right time. This is an excellent way to enhance your company profile and communicate effectively to your target audience. BENEFITS OF SPONSORING • Showcase new products • Raise awareness of your operation • Improve perception of your brand • Influence other organisations’ spending plans For more information please call +44 (0)20 7973 1309 or email [email protected] PROGRAMME
TUESDAY 25 NOVEMBER 2014
08:30 REGISTRATION AND REFRESHMENTS
09:00 CHAIR’S WELCOME Dr. Georges Limbert, National Centre for Advanced Tribology, University of Southampton
09:10 PREDICTIVE MODELLING OF THE STATIC AND DYNAMIC FRICTION BEHAVIOUR OF HUMAN SKIN Dr. Marc Masen, Department of Mechanical Engineering, Imperial College • Friction and the prevention of Decubitus Ulcers • Modelling and measuring friction of the human skin • Relation contact, friction and experience
09:35 UNDERSTANDING THE GENERIC INFLUENCE OF MOISTURE ON THE FRICTION OF SKIN FROM THE CONTACT MECHANICS OF THE FINGER PAD Prof. Michael Adams, School of Chemical Engineering, University of Birmingham • Influence of secreted sweat on the friction of the finger pad • A kinetic description of the changes in the contact mechanics • Role of hydrophobicity, roughness and permeability of contacting surfaces
10:00 A COMPARISON OF THE TRIBOLOGICAL BEHAVIOUR OF EX-VIVO HUMAN, TISSUE-ENGINEERED AND SYNTHETIC SKIN Prof. Roger Lewis and Dr. Matt Carré, Department of Mechanical Engineering, University of Sheffield • A comparison of friction behaviour • Understanding the effects of moisture • Characterising tissue damage
10:25 Q&A SESSION
10:40 NETWORKING REFRESHMENT BREAK
11:10 BIOTRIBOLOGY: CHALLENGES IN HEALTHCARE AND PERSONAL CARE DEVICE DEVELOPMENT Dr. Steve Franklin, Chief Technologist, Tribology & Human Tissue Interaction, Philips Research • How does biotribology influence applications in healthcare and personal care? • What are the biotribology challenges in relation to device development?
11:35 SKIN DEEP IN MODELLING: FROM WRINKLES TO BIOMIMETIC SURFACES Dr. Georges Limbert, National Centre for Advanced Tribology, University of Southampton • How modelling techniques are used to elucidate the complex mechanics of skin • Interplay between material and structural properties • The physics of skin wrinkles: understanding and exploitation
12:00 Q&A SESSION
12:10 NETWORKING LUNCH
13:10 EVALUATING THE IMPACT OF SUN EXPOSURE ON THE SKIN BARRIER USING A BIOMECHANICS FRAMEWORK Dr. Kemal Levi, Founder, Bio-X Consulting • How does the stress state of skin and its mechanical properties change with sun exposure? • Measuring the propensity for sun-induced skin damage and the efficacy of sun protection strategies in alleviating this damage 13:35 HOW MICROCLIMATE FACTORS INFLUENCE THE INTEGRITY OF THE LOADED SKIN INTERFACE Prof. Dan Bader, Faculty of Health Sciences, University of Southampton • The effects of temperature and humidity of the metabolism of loaded skin • Model systems to monitor temperature and humidity • Bioengineering strategies to prevent mechanical-induced skin breakdown
14:00 EXPLOITING INHERENT PROPERTIES OF DERMAL PAPILLA CELLS TO ENGINEER A HAIR FOLLICLE Dr. Claire Higgins, Department of Bioengineering, Imperial College • Epithelial: mesenchymal interactions in the follicle • The concept of follicle neogenesis • Artificial skins
14:25 Q&A SESSION
14:40 NETWORKING REFRESHMENT BREAK
15:10 INVERSE METHOD TO ASSESS IN VIVO THE MECHANICAL PROPERTIES OF THE SKIN LAYERS Dr. Roberto Santoprete, Senior Research Engineer, L’Oréal Research and Innovation • Approach coupling of three experimental devices with a multi-layer biomechanical model of the skin • Application to study the effect of a moisturiser • Application to study the effect of ageing
15:35 MECHANICAL PROPERTIES OF THE TOP-LAYERS OF HUMAN SKIN Dr. Cees Oomens, Associate Professor in Biomechanics and Continuum Mechanics, Eindhoven University of Technology • An overview of a series of indentation and shear tests on isolated stratum corneum, epidermis and dermis • A new method to measure in-vitro local shear properties of skin using inverse methods • A first proposal for a non-linear, visco-elastic constitutive model for the top-layers of skin
16:00 MEASURING MECHANICAL PROPERTIES OF THE SKIN Prof. Sam Evans, Deputy Director, Institute of Mechanical and Manufacturing Engineering, Cardiff University
16:25 Q&A SESSION
16:40 CHAIR’S CLOSING COMMENTS Dr. Georges Limbert, National Centre for Advanced Tribology, University of Southampton
17:00 END OF SEMINAR
Find out more about our speakers at www.imeche.org/events/S6128 • This programme is subject to change. • The Institution is not responsible for the views or opinions expressed by individual speakers.
With thanks to: Dr. Georges Limbert, National Centre for Advanced Tribology, University of Southampton SPEAKERS AND CONTRIBUTORS
DR. GEORGES LIMBERT CHAIR NATIONAL CENTRE FOR ADVANCED TRIBOLOGY, UNIVERSITY OF SOUTHAMPTON Georges Limbert joined nCATS as an Assistant Professor in Mathematical THE BIOMEDICAL Modelling in Biotribology in 2009. His current research focuses on the modelling of skin biophysics, the continuum mechanics of biological soft tissue structures ENGINEERING and biomaterials and novel computational techniques for thin structures. ASSOCIATION AT Georges has expertise in non-linear continuum/computational mechanics THE INSTITUTION and the formulation of constitutive models for biomaterials, biological tissues and structures. He is a Chartered Engineer and Fellow of the Institution of OF MECHANICAL Mechanical Engineers, sits on the board of the Engineering in Medicine and ENGINEERS IS THE Health Division of the Institution (since 2004) and chairs the Technical Activity LARGEST GROUP Committee on Skin that he established in 2012. OF PROFESSIONAL BIOMEDICAL DR. STEVE FRANKLIN ENGINEERS IN THE UK. CHIEF TECHNOLOGIST, TRIBOLOGY & HUMAN TISSUE - The Biomedical Engineering INTERACTION, PHILIPS RESEARCH Association (BmEA) Steve Franklin joined Philips Electronics in 1986, starting his career working on coatings and surface treatments, tribology, lifetime performance and reliability, biotribology and device-human tissue interactions. He initially achieved a BSc 1st Class Hons. in Applied Physics and Materials Science from Sheffield Hallam University, followed by a PhD in Metallurgy at Loughborough University. Steve is also a visiting Industrial Professor in Tribology/Biotribology/Human Tissue Interaction at the University of Sheffield.
DR. CLAIRE HIGGINS DEPARTMENT OF BIOENGINEERING, IMPERIAL COLLEGE Claire Higgins received a PhD in Skin Developmental Biology from Durham University in 2007. She then moved to the Department of Dermatology at Columbia University in New York for postdoctoral training before joining the Department of Bioengineering at Imperial as a Lecturer in April this year. As a postdoc, she received a Career Development Award from the Dermatology Foundation to research the ‘Molecular Basis of Human Hair Follicle Induction.’ At Imperial, the main focus of the research group is to understand mechanisms of skin and hair development and regeneration, both during homeostasis and in response to disease or injury.
DR. CEES OOMENS ASSOCIATE PROFESSOR IN BIOMECHANICS AND CONTINUUM MECHANICS, EINDHOVEN UNIVERSITY OF TECHNOLOGY Cees Oomens is Associate Professor in Biomechanics and Continuum Mechanics. He studied Physics at Eindhoven University of Technology and obtained his PhD at the University of Twente, studying the mechanical behaviour of skin. Currently his research is focused on damage and adaptation of soft biological tissues. A major application field is the study on the aetiology of pressure ulcers. The goals are to develop an objective method to identify patients at risk of developing a pressure ulcer and to develop techniques for early detection of deep tissue injury. He is the first author of the text book ‘Biomechanics: Concepts and Computation.’
DR. ROBERTO SANTOPRETE SENIOR RESEARCH ENGINEER, L’ORÉAL RESEARCH & INNOVATION Roberto Santoprete has a PhD in semiconductor physics and since 2005 has been in charge of the development of multi-physics modelling approaches to help design new cosmetic treatments for skin and hair. Roberto currently works for the Physics Department at L’Oréal Research & Innovation.
PROFESSOR SAM EVANS DEPUTY DIRECTOR, INSTITUTE OF MECHANICAL AND MANUFACTURING ENGINEERING, CARDIFF UNIVERSITY Sam Evans joined the Cardiff School of Engineering in 1996 from the University of Southampton. His particular interests lie in biomaterials and nanocomposites, specifically the fatigue of biomaterials such as bone cement and aerospace materials, the use of acoustic emission and ultrasound techniques to detect damage, and computational modelling using finite element and boundary element models. Further interests include the use of digital image correlation techniques to measure strain distribution in bones, skin, implants and aerospace components, and the development of constitutive models and new implicit solution algorithms for skin and soft tissues. SPEAKERS AND CONTRIBUTORS
PROFESSOR ROGER LEWIS DEPARTMENT OF MECHANICAL ENGINEERING, UNIVERSITY OF SHEFFIELD Roger Lewis heads a group investigating a wide range of industrial tribological THE AIM OF THE issues. One of his main themes is human tribology, including skin friction, BIOMEDICAL damage and medical device interactions with human tissue, but also including ENGINEERING teeth cleaning and leg waxing. ASSOCIATION IS TO BRING TOGETHER KEY WORKERS FROM BOTH MEDICINE DR. MATT CARRÉ AND ENGINEERING DEPARTMENT OF MECHANICAL ENGINEERING, UNIVERSITY OF TO DISCUSS THE SHEFFIELD LATEST ADVANCES Matt Carré leads a group working closely on the area of skin tribology, initially AND ISSUES, TO carrying out investigations through an undergraduate project on rugby ball handling performance. This has since led to the completion of four PhD studies ENABLE NETWORKING and numerous papers on the fundamental understanding of the effects of surface AMONG DIFFERENT roughness, moisture and loading on skin tribology, as well as a range of medical INDUSTRY LEADERS, and consumer applications. They are currently working on a major EPSRC project to link OCT (Optical Coherence Tomography) measurements with human AND TO PROMOTE skin behaviour, as well as the UNITISS Marie Curie project with Philips on THIS GROWING FIELD catheterisation. TO GOVERNMENT, HEALTHCARE PROFESSIONALS AND PROFESSOR MICHAEL ADAMS THE WIDER PUBLIC. SCHOOL OF CHEMICAL ENGINEERING, UNIVERSITY OF - The Biomedical Engineering BIRMINGHAM Association (BmEA) Michael Adams has published over 170 scientific papers, book reviews, book chapters on particle technology, as well as co-editing four books on Tribology in Particulate Technology, Theoretical and Computational Methods in Tribology, Solid-Solid Interactions and Dynamics of Complex Fluids. He has co-ordinated major grants from the TSB and the EU including a current FP7 project. As an academic lead for the Science City Research Alliance, he is responsible for a laboratory that has specialist facilities to study advanced materials and biomaterials.
DR. MARC MASEN DEPARTMENT OF MECHANICAL ENGINEERING, IMPERIAL COLLEGE Marc Masen received his MSc and PhD degrees in Mechanical Engineering from the University of Twente. He joined Imperial College as a Senior Lecturer in 2013. Marc’s main areas of research are Tribology of Human Tissue and Wear Mechanisms. Recent work includes the development of analytical models for the contact and friction behaviour of compliant, visco-elastic materials, an investigation of the wear behaviour of UHMWPE for use in implants and the design of a novel portable tribometer that has been used in the development of a statistics-based model for friction forces in human skin contacts.
PROFESSOR DAN BADER FACULTY OF HEALTH SCIENCES, UNIVERSITY OF SOUTHAMPTON Dan Bader studied Physics at Liverpool University, followed by an MSc in Medical Physics and a PhD at Southampton University. He later moved to Queen Mary, University of London (QMUL) as a lecturer in biomaterials and was one of the core research staff in the IRC in Biomedical Materials. In 1999, he was appointed Professor of Medical Engineering in the Department of Engineering (QMUL). In 2011, he joined the Faculty of Health Sciences at the University of Southampton, where his multidisciplinary team is establishing bioengineering strategies to maintain skin health. He has published over 180 refereed scientific papers and edited three books.
DR. KEMAL LEVI FOUNDER, BIO-X CONSULTING Kemal Levi is a researcher, entrepreneur and scientific consultant for medical devices and biotechnology industries. He is the founder of Bio-X Consulting, a technology and consulting firm that partners with clients in technology innovation and development. He has authored numerous patents and publications in his field and is a frequent speaker on skin mechanics and reliability. Kemal received his doctorate in Materials Science and Engineering from Stanford University. RECENT ADVANCES IN THE BOOKING FORM TRIBOLOGY AND BIOENGINEERING EVENT CODE: S6128AB OF THE SKIN FIVE WAYS TO BOOK 25 November 2014 1 Online: One Birdcage Walk, London. SW1H 9JJ www.imeche.org/events/S6128 REGISTRATION Please complete in capitals. 2 Email: [email protected] Family Name Title (Mr, Mrs, Miss) 3 Phone: First Name Job Title +44 (0)20 7973 1258 Membership No Institution 4 Post completed booking form to: Name of Organisation (for name badge) Event Registrations Address for correspondence Institution of Mechanical Engineers 1 Birdcage Walk Town/City London SW1H 9JJ Postcode 5 Fax: Contact Telephone +44 (0)20 7304 6845
Email Please read the information listed below as Do you have any special requirements? each booking is subject to the Institution’s standard terms and conditions. CONDITIONS OF BOOKING How did you hear about this event? o Direct mail o Website o Colleague o Other Completed application forms should be returned to the address above, along with the We would like to keep you informed of relevant services that may be of benefit to you. correct payment. Attendance at the event will Please tick the boxes below to let us know what you’re interested in: be confirmed on receipt of the full balance. All participants are advised to bring a copy o Events and training opportunities of their confirmation with them on the day, to ensure the fastest possible entry. o News and updates from the Institution SPECIAL REQUIREMENTS o Services and offers from our preferred partners Please inform us of any special requirements, ie. dietary or access, on the relevant section of this form. CANCELLATION FEES AND CHARGES Please complete the appropriate box. For a refund (minus £25 +VAT admin charge), cancellations must be received at least 14 days Registration fees include entry to the sessions, refreshments, lunch and a copy of the event proceedings. prior to the event. Replacement delegates are welcome at any time. The Institution reserves the right to cancel any event. In this case, FEE VAT TOTAL the full fee will be refunded unless a mutually convenient transfer can be arranged. In the Member, Institution of Mechanical event that the Institution postpones an event £300.00 £60.00 £ for any reason and the delegate is unable or Engineers unwilling to attend on the rescheduled date, they will receive a full refund of the fee paid. Member, supporting organisation £300.00 £60.00 £ The Institution is not responsible for any loss or damage as a result of a substitution, alteration or cancellation/postponement of Non-member £410.00 £82.00 £ an event. The Institution shall assume no liability whatsoever if this event is cancelled, rescheduled or postponed due to a fortuitous Student/retired £80.00 £16.00 £ event, Act of God, unforeseen occurrence or any other event that renders performance of this conference impracticable, illegal or impossible. For purposes of this clause, a fortuitous event shall include, but not be limited to: war, fire, labour strike, extreme weather or other emergency. PAYMENT DETAILS Please note that while speakers and topics Payment must accompany this registration form. Registration will be confirmed only on were confirmed at the time of publishing, receipt of full payment. circumstances beyond the control of the organisers may necessitate substitutions, PLEASE INDICATE METHOD OF PAYMENT: alterations or cancellations of the speakers and/or topics. As such, the Institution o Cheque Cheques should be made payable to IMechE and crossed. Please note international delegates reserves the right to alter or modify the may pay only by credit card, BACS or banker’s draft. A copy of the draft must accompany this form. It is the advertised speakers and/or topics if necessary delegate’s responsibility to pay any bank charges. without any liability to you whatsoever. Any substitutions or alterations will be updated on o Credit Card the event’s webpage as soon as possible.
Card type: o Visa o MasterCard (please note we cannot accept American Express, Diners Club or Maestro) LIABILITY Card No Valid From / Expiry Date / The organisers do not accept liability for any injuries or losses of any nature incurred by Name of Cardholder delegates and/or accompanying persons, nor for loss or damage to their luggage and/or Billing Address of Cardholder (if different from above) personal belongings. Postcode VENUE Amount to be Deducted Signature One Birdcage Walk, Westminster, London SW1H 9JJ o BACS BACS bank transfers can be made to: IMechE Current Account, NatWest Charing Cross Branch. ACCOMMODATION Sort Code: 60-40-05 Acc No: 00817767 We have arranged special discounted rates at local hotels via the Corporate Team. Swift Code: NWBKGB2L IBAN Code: GB96NWBK60400500817767 Quote ID Number 8488ME A copy of the draft must accompany this form. www.corporateteam.com/events/8488ME o Invoice (UK residents only) Delegates wishing to be invoiced must provide an order number. Tel: +44 (0)20 7592 3050 If your company does not use order numbers please include a formal request for invoicing on your company’s E-mail: [email protected] letterhead. A charge of £10 +VAT will be made to cover additional administration costs. Invoices are payable on receipt and no alterations to these terms will be accepted. ENQUIRIES For event enquiries please call Order No +44 (0)20 7973 1258 or email [email protected] Contact Name Name and Address for Invoicing The Institution of Mechanical Engineers is a registered charity (no 206882) Postcode VAT No GB299930493. Tel Fax We are the market leader among professional FORWARD engineering bodies. We’ve been supporting engineers since 1847 and have 110,000 members in over 140 countries, working in the world’s most dynamic and THINKING important industries. Our comprehensive events programme brings you the latest research and best practice from industry and academia.
OTHER EVENTS TO LOOK FOR:
CELEBRATING OUR PROFESSION.
4 November 2014 20 November 2014 10 November 2015 Sheffield Dorchester Hotel, London London COMBATING 21ST ANNUAL DINNER INCONTINENCE: THE CENTURY CHALLENGES IN The Institution of Mechanical Engineers’ ENGINEERING CHALLENGE X MANUFACTURING: REDUCING Annual Dinner for 2014 will once again return Examine existing solutions and solve to London’s Dorchester Hotel. current engineering problems in the world FRICTION, VIBRATION AND of incontinence. New technologies will be WEAR showcased that could revolutionise current This seminar will provide you with the thinking. opportunity to hear lessons learnt and best- practices across the manufacturing industry to increase process optimisation.
www.imeche.org/events/S6169 www.imeche.org/events/O1558 www.imeche.org/events/C6177
INFORMATION AND BOOKINGS CALL: +44 (0)20 7973 1258 EMAIL: [email protected] VISIT: www.imeche.org/events
JOURNALS MEMBERSHIP GET INVOLVED You may be interested in Skin Whether you’re a student, apprentice, Whether you’re new to the profession or Research & Technology Proceedings graduate, qualified engineer or just have well established, volunteering is a great IMechE, Part H an interest in engineering, Institution way to gain new skills, knowledge and membership offers the highest professional experience. Professional Engineering Publishing prestige. As an Ambassador you have the chance is the publisher for the Institution Professional registration is a valuable to represent your profession and give of Mechanical Engineers. For more investment for any engineer who is serious something back to the engineering information about our magazines, journals about their career. community as well as inspiring the next and conference proceedings visit generation. www.uk.sagepub.com/imeche Find out which level you’re best suited for at www.imeche.org/membership or See www.imeche.org/volunteering To find out more contact Subscriptions email us on [email protected] for more information or go to on +44 (0)1952 214050 or email http://nearyou.imeche.org [email protected]
Continuing Professional Development (CPD) 1 Birdcage Walk Our online Career Developer tool can help you: Westminster • Plan Create an Action Plan and identify targets London • Record Download a record of your learning activities SW1H 9JJ • Review Reflect on your professional development Register for Career Developer and get more from your career T +44 (0)20 7222 7899 www.imeche.org/careerdeveloper www.imeche.org For tailored advice contact [email protected]
Improving the world through engineering