Astrobiology and the Possibility of Life on Earth and Elsewhere…
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Glossary - Cellbiology
1 Glossary - Cellbiology Blotting: (Blot Analysis) Widely used biochemical technique for detecting the presence of specific macromolecules (proteins, mRNAs, or DNA sequences) in a mixture. A sample first is separated on an agarose or polyacrylamide gel usually under denaturing conditions; the separated components are transferred (blotting) to a nitrocellulose sheet, which is exposed to a radiolabeled molecule that specifically binds to the macromolecule of interest, and then subjected to autoradiography. Northern B.: mRNAs are detected with a complementary DNA; Southern B.: DNA restriction fragments are detected with complementary nucleotide sequences; Western B.: Proteins are detected by specific antibodies. Cell: The fundamental unit of living organisms. Cells are bounded by a lipid-containing plasma membrane, containing the central nucleus, and the cytoplasm. Cells are generally capable of independent reproduction. More complex cells like Eukaryotes have various compartments (organelles) where special tasks essential for the survival of the cell take place. Cytoplasm: Viscous contents of a cell that are contained within the plasma membrane but, in eukaryotic cells, outside the nucleus. The part of the cytoplasm not contained in any organelle is called the Cytosol. Cytoskeleton: (Gk. ) Three dimensional network of fibrous elements, allowing precisely regulated movements of cell parts, transport organelles, and help to maintain a cell’s shape. • Actin filament: (Microfilaments) Ubiquitous eukaryotic cytoskeletal proteins (one end is attached to the cell-cortex) of two “twisted“ actin monomers; are important in the structural support and movement of cells. Each actin filament (F-actin) consists of two strands of globular subunits (G-Actin) wrapped around each other to form a polarized unit (high ionic cytoplasm lead to the formation of AF, whereas low ion-concentration disassembles AF). -
Imaginative Geographies of Mars: the Science and Significance of the Red Planet, 1877 - 1910
Copyright by Kristina Maria Doyle Lane 2006 The Dissertation Committee for Kristina Maria Doyle Lane Certifies that this is the approved version of the following dissertation: IMAGINATIVE GEOGRAPHIES OF MARS: THE SCIENCE AND SIGNIFICANCE OF THE RED PLANET, 1877 - 1910 Committee: Ian R. Manners, Supervisor Kelley A. Crews-Meyer Diana K. Davis Roger Hart Steven D. Hoelscher Imaginative Geographies of Mars: The Science and Significance of the Red Planet, 1877 - 1910 by Kristina Maria Doyle Lane, B.A.; M.S.C.R.P. Dissertation Presented to the Faculty of the Graduate School of The University of Texas at Austin in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy The University of Texas at Austin August 2006 Dedication This dissertation is dedicated to Magdalena Maria Kost, who probably never would have understood why it had to be written and certainly would not have wanted to read it, but who would have been very proud nonetheless. Acknowledgments This dissertation would have been impossible without the assistance of many extremely capable and accommodating professionals. For patiently guiding me in the early research phases and then responding to countless followup email messages, I would like to thank Antoinette Beiser and Marty Hecht of the Lowell Observatory Library and Archives at Flagstaff. For introducing me to the many treasures held deep underground in our nation’s capital, I would like to thank Pam VanEe and Ed Redmond of the Geography and Map Division of the Library of Congress in Washington, D.C. For welcoming me during two brief but productive visits to the most beautiful library I have seen, I thank Brenda Corbin and Gregory Shelton of the U.S. -
Solar System Simulator NASA SUMMER of INNOVATION
National Aeronautics and Space Administration Solar System Simulator NASA SUMMER OF INNOVATION UNIT Earth and Space Science – Year of the Solar System DESCRIPTION This online software generates views of GRADE LEVELS the bodies of our planetary system at any th th 7 – 9 date from any artificial or natural point of observation. CONNECTION TO CURRICULUM Science and technology OBJECTIVES TEACHER PREPARATION TIME Students will: 1 hour • Investigate how to determine the relative position of the sun, LESSON TIME NEEDED planets, and a number of 30 minutes Complexity: Basic planetary spacecraft using a simple web-based program • Explore how planets change their position in space over time NATIONAL STANDARDS National Science Education Standards (NSTA) Science and Technology Standards • Abilities of technological design • Understanding about science and technology Earth and Space Science • Earth in the solar system • Objects in the sky Common Core State Standards for Mathematics (NCTM) Number and Operations in Base Ten • Perform operations with multi-digit whole numbers and with decimals to hundredths Operations and Algebraic Thinking • Generate and analyze patterns ISTE NETS and Performance Indicators for Students (ISTE) Creativity and Innovation • Use models and simulations to explore complex systems and issues. Technology Operations and Concepts • Understand and use technology systems Aerospace Education Services Project MANAGEMENT MATERIALS Take time to practice with this software. While simple, it offers a • Computer with Internet variety of views with which to become familiar. access On the simulator homepage, a FIELD OF VIEW of 2 will show the inner solar system very nicely. It will be difficult to see the position of ALL the planets at one time. -
Submission from Jerry Cuttler
CMD 21-H4.22 File / dossier : 6.01.07 Date: 2021-05-03 Edocs: 6553919 Oral Presentation Exposé oral Written submission from Mémoire de Jerry Cuttler Jerry Cuttler In the Matter of the À l’égard de Darlington New Nuclear Project Projet de nouvelle centrale nucléaire de Darlington Application to renew the nuclear power Demande de renouvellement du permis de reactor site preparation licence for the préparation de l’emplacement d’une centrale Darlington New Nuclear Project nucléaire pour le projet de nouvelle centrale nucléaire de Darlington Commission Public Hearing Audience publique de la Commission June 10, 2021 10 juin 2021 Intervenor Report for CNSC Public Hearing by Dr. Jerry M. Cuttler, D.Sc., P.Eng. Vaughan, Ontario, Canada regarding Ontario Power Generation’s Application for renewal of its site preparation licence for the Darlington New Nuclear Project to be held June 10, 2021 Part A: Review of the licence renewal documents Part B: Evidence of beneficial effects of radiation and thresholds for detriment Intervenor written report Objective PFP contribution agreement PFP 2020 DNNP01 Cuttler, Section 2.2 requires: 1) participation in the proceedings of the Public Hearing on the OPG application to renew its site licence for the Darlington New Nuclear Project (DNNP), 2) review of the OPG licence renewal application and related documentation, including OPG and CNSC CMDs, and comment in its feasibility and safety aspects. The analysis must focus on OPG’s proposed site preparation licence. 3) submission of a written report summarizing comments from the review, 4) a presentation at the June 10, 2021 virtual Public Hearing. -
Bayesian Analysis of the Astrobiological Implications of Life's
Bayesian analysis of the astrobiological implications of life's early emergence on Earth David S. Spiegel ∗ y, Edwin L. Turner y z ∗Institute for Advanced Study, Princeton, NJ 08540,yDept. of Astrophysical Sciences, Princeton Univ., Princeton, NJ 08544, USA, and zInstitute for the Physics and Mathematics of the Universe, The Univ. of Tokyo, Kashiwa 227-8568, Japan Submitted to Proceedings of the National Academy of Sciences of the United States of America Life arose on Earth sometime in the first few hundred million years Any inferences about the probability of life arising (given after the young planet had cooled to the point that it could support the conditions present on the early Earth) must be informed water-based organisms on its surface. The early emergence of life by how long it took for the first living creatures to evolve. By on Earth has been taken as evidence that the probability of abiogen- definition, improbable events generally happen infrequently. esis is high, if starting from young-Earth-like conditions. We revisit It follows that the duration between events provides a metric this argument quantitatively in a Bayesian statistical framework. By (however imperfect) of the probability or rate of the events. constructing a simple model of the probability of abiogenesis, we calculate a Bayesian estimate of its posterior probability, given the The time-span between when Earth achieved pre-biotic condi- data that life emerged fairly early in Earth's history and that, billions tions suitable for abiogenesis plus generally habitable climatic of years later, curious creatures noted this fact and considered its conditions [5, 6, 7] and when life first arose, therefore, seems implications. -
Messengers from Outer Space
The complete absence of national laboratories for standardizing radiation measurements and the lack of physics departments in most radiotherapy centres in Latin America warrant the setting up of one or more regional dosimetry facilities, the functions of which would be primarily to calibrate dosimeters; to provide local technical assistance by means of trained staff; to check radiation equipment and dosimeters; to arrange a dose-intercomparison service; and to co-operate with local personnel dosimetry services. To be most effective, this activity should be in the charge of local personnel, with some initial assistance in the form of equipment and experts provided by the Agency. Although the recommendations were presented to the IAEA as the or ganization responsible for the setting up of the panel, the participants re commended that the co-operation of the World Health Organization and the Pan-American Health Organization should be invited. It was also suggested that the panel report be circulated to public health authorities in the countries represented. MESSENGERS FROM OUTER SPACE Although no evidence has yet been confirmed of living beings reaching the earth from space, it has been estimated that hundreds of tons of solid matter arrive every day in the form of meteorites or cosmic dust particles. Much is destroyed by heat in the atmosphere but fragments recovered can give valuable information about what has been happening in the universe for billions of years. Some of the results of worldwide research on meteorites were given at a symposium in Vienna during August. During six days of discussions a total of 73 scientific papers was present ed and a special meeting was held for the purpose of improving international co-operation in the research. -
The Space Race
The Space Race Aims: To arrange the key events of the “Space Race” in chronological order. To decide which country won the Space Race. Space – the Final Frontier “Space” is everything Atmosphere that exists outside of our planet’s atmosphere. The atmosphere is the layer of Earth gas which surrounds our planet. Without it, none of us would be able to breathe! Space The sun is a star which is orbited (circled) by a system of planets. Earth is the third planet from the sun. There are nine planets in our solar system. How many of the other eight can you name? Neptune Saturn Mars Venus SUN Pluto Uranus Jupiter EARTH Mercury What has this got to do with the COLD WAR? Another element of the Cold War was the race to control the final frontier – outer space! Why do you think this would be so important? The Space Race was considered important because it showed the world which country had the best science, technology, and economic system. It would prove which country was the greatest of the superpowers, the USSR or the USA, and which political system was the best – communism or capitalism. https://www.youtube.com/watch?v=xvaEvCNZymo The Space Race – key events Discuss the following slides in your groups. For each slide, try to agree on: • which of the three options is correct • whether this was an achievement of the Soviet Union (USSR) or the Americans (USA). When did humans first send a satellite into orbit around the Earth? 1940s, 1950s or 1960s? Sputnik 1 was launched in October 1957. -
The Water on Mars Vanished. This Might Be Where It Went
The water on Mars vanished. This might be where it went. timesofindia.indiatimes.com/home/science/the-water-on-mars-vanished-this-might-be-where- it-went-/articleshow/81599751.cms NYT News Service | Mar 20, 2021, 10:32 IST Mars was once wet, with an ocean’s worth of water on its surface. Today, most of Mars is as dry as a desert except for ice deposits in its polar regions. Where did the rest of the water go? Some of it disappeared into space. Water molecules, pummeled by particles of solar wind, broke apart into hydrogen and oxygen atoms, and those, especially the lighter hydrogen atoms, sped out of the atmosphere, lost to outer space. A tall outcropping of rock, with layered deposits of sediments in the distance, marking a remnant of an ancient, long-vanished river delta in Jezero Crater, are pictured in this undated image taken by NASA's Mars rover Perseverance. (Reuters) But most of the water, a new study concludes, went down, sucked into the red planet’s rocks. And there it remains, trapped within minerals and salts. Indeed, as much as 99% of the water that once flowed on Mars could still be there, the researchers estimated in a paper published this week in the journal Science. Data from the past two decades of robotic missions to Mars, including NASA ’s Curiosity rover and the Mars Reconnaissance Orbiter, showed a wide distribution of what geologists call hydrated minerals. “It became very, very clear that it was common and not rare to find evidence of water alteration,” said Bethany Ehlmann, a professor of planetary science at the California Institute of Technology and one of the authors of the paper. -
The Chemical Origin of Behavior Is Rooted in Abiogenesis
Life 2012, 2, 313-322; doi:10.3390/life2040313 OPEN ACCESS life ISSN 2075-1729 www.mdpi.com/journal/life Article The Chemical Origin of Behavior is Rooted in Abiogenesis Brian C. Larson, R. Paul Jensen and Niles Lehman * Department of Chemistry, Portland State University, P.O. Box 751, Portland, OR 97207, USA; E-Mails: [email protected] (B.C.L.); [email protected] (R.P.J.) * Author to whom correspondence should be addressed; E-Mail: [email protected]; Tel.: +1-503-725-8769. Received: 6 August 2012; in revised form: 29 September 2012 / Accepted: 2 November 2012 / Published: 7 November 2012 Abstract: We describe the initial realization of behavior in the biosphere, which we term behavioral chemistry. If molecules are complex enough to attain a stochastic element to their structural conformation in such as a way as to radically affect their function in a biological (evolvable) setting, then they have the capacity to behave. This circumstance is described here as behavioral chemistry, unique in its definition from the colloquial chemical behavior. This transition between chemical behavior and behavioral chemistry need be explicit when discussing the root cause of behavior, which itself lies squarely at the origins of life and is the foundation of choice. RNA polymers of sufficient length meet the criteria for behavioral chemistry and therefore are capable of making a choice. Keywords: behavior; chemistry; free will; RNA; origins of life 1. Introduction Behavior is an integral feature of life. Behavior is manifest when a choice is possible, and a living entity responds to its environment in one of multiple possible ways. -
51. Astrobiology: the Final Frontier of Science Education
www.astrosociety.org/uitc No. 51 - Summer 2000 © 2000, Astronomical Society of the Pacific, 390 Ashton Avenue, San Francisco, CA 94112. Astrobiology: The Final Frontier of Science Education by Jodi Asbell-Clarke and Jeff Lockwood What (or Whom) Are We Looking For? Where Do We Look? Lessons from Our Past The Search Is On What Does the Public Have to Learn from All This? A High School Curriculum in Astrobiology Astrobiology seems to be all the buzz these days. It was the focus of the ASP science symposium this summer; the University of Washington is offering it as a new Ph.D. program, and TERC (Technical Education Research Center) is developing a high school integrated science course based on it. So what is astrobiology? The NASA Astrobiology Institute defines this new discipline as the study of the origin, evolution, distribution, and destiny of life in the Universe. What this means for scientists is finding the means to blend research fields such as microbiology, geoscience, and astrophysics to collectively answer the largest looming questions of humankind. What it means for educators is an engaging and exciting discipline that is ripe for an integrated approach to science education. Virtually every topic that one deals with in high school science is embedded in astrobiology. What (or Whom) Are We Looking For? Movies and television shows such as Contact and Star Trek have teased viewers with the idea of life on other planets and even in other galaxies. Illustration courtesy of and © 2000 by These fictional accounts almost always deal with intelligent beings that have Kathleen L. -