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Role in Skeletal Muscle Atrophy ���������������������������������������������������������������������������������������� 267 Anastasia Thoma and Adam P

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Role in Skeletal Muscle Atrophy ���������������������������������������������������������������������������������������� 267 Anastasia Thoma and Adam P Advances in Experimental Medicine and Biology 1088 Junjie Xiao Editor Muscle Atrophy Advances in Experimental Medicine and Biology Volume 1088 Editorial Board IRUN R. COHEN, The Weizmann Institute of Science, Rehovot, Israel ABEL LAJTHA, N.S.Kline Institute for Psychiatric Research, Orangeburg, NY, USA JOHN D. LAMBRIS, University of Pennsylvania, Philadelphia, PA, USA RODOLFO PAOLETTI, University of Milan, Milan, Italy NIMA REZAEI, Tehran University of Medical Sciences, Children’s Medical Center Hospital, Tehran, Iran More information about this series at http://www.springer.com/series/5584 Junjie Xiao Editor Muscle Atrophy Editor Junjie Xiao Cardiac Regeneration and Ageing Lab, Institute of Cardiovascular Sciences, School of Life Science Shanghai University Shanghai, China ISSN 0065-2598 ISSN 2214-8019 (electronic) Advances in Experimental Medicine and Biology ISBN 978-981-13-1434-6 ISBN 978-981-13-1435-3 (eBook) https://doi.org/10.1007/978-981-13-1435-3 Library of Congress Control Number: 2018958628 © Springer Nature Singapore Pte Ltd. 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore Contents Part I Overview 1 An Overview of Muscle Atrophy ������������������������������������������������������������ 3 Shengguang Ding, Qiying Dai, Haitao Huang, Yiming Xu, and Chongjun Zhong Part II Basic Aspects of Muscle Atrophy 2 Myofibers �������������������������������������������������������������������������������������������������� 23 Dragos Cretoiu, Luciana Pavelescu, Florentina Duica, Mihaela Radu, Nicolae Suciu, and Sanda Maria Cretoiu 3 Muscle Mass, Quality, and Composition Changes During Atrophy and Sarcopenia �������������������������������������������������������������������������� 47 Yosuke Yamada 4 Muscle Changes During Atrophy . 73 Adrian Dumitru, Beatrice Mihaela Radu, Mihai Radu, and Sanda Maria Cretoiu 5 Skeletal Muscle Damage in Intrauterine Growth Restriction . 93 Leonard Năstase, Dragos Cretoiu, and Silvia Maria Stoicescu Part III Molecular Mechanisms of Muscle Atrophy 6 The Role of IGF-1 Signaling in Skeletal Muscle Atrophy �������������������� 109 Louk T. Timmer, Willem M. H. Hoogaars, and Richard T. Jaspers 7 mTOR Signaling Pathway and Protein Synthesis: From Training to Aging and Muscle Autophagy . 139 Jocemar Ilha, Caroline Cunha do Espírito-Santo, and Gabriel Ribeiro de Freitas v vi Contents 8 Past, Present, and Future Perspective of Targeting Myostatin and Related Signaling Pathways to Counteract Muscle Atrophy �������� 153 Willem M. H. Hoogaars and Richard T. Jaspers 9 Hormones and Muscle Atrophy �������������������������������������������������������������� 207 Ana Isabel Martín, Teresa Priego, and Asunción López-Calderón 10 Ubiquitin-Proteasome Pathway and Muscle Atrophy �������������������������� 235 Rania Khalil 11 Noncoding RNAs in Muscle Atrophy . 249 Yongqin Li, Xiangmin Meng, Guoping Li, Qiulian Zhou, and Junjie Xiao 12 NF-kB and Inflammatory Cytokine Signalling: Role in Skeletal Muscle Atrophy ���������������������������������������������������������������������������������������� 267 Anastasia Thoma and Adam P. Lightfoot 13 Redox Homeostasis in Age-Related Muscle Atrophy ���������������������������� 281 Giorgos K. Sakellariou and Brian McDonagh 14 Disturbed Ca2+ Homeostasis in Muscle- Wasting Disorders . 307 Guillermo Avila Part IV Muscle Atrophy in Diseases and Aging 15 Muscle Atrophy in Cancer ���������������������������������������������������������������������� 329 Jian Yang, Richard Y. Cao, Qing Li, and Fu Zhu 16 The Molecular Mechanisms and Prevention Principles of Muscle Atrophy in Aging �������������������������������������������������������������������� 347 Yu Zhang, Xiangbin Pan, Yi Sun, Yong-jian Geng, Xi-Yong Yu, and Yangxin Li 17 Muscular Atrophy in Cardiovascular Disease . 369 Isadora Rebolho Sisto, Melina Hauck, and Rodrigo Della Méa Plentz 18 Muscle Atrophy in Chronic Kidney Disease ������������������������������������������ 393 Jociane Schardong, Miriam Allein Zago Marcolino, and Rodrigo Della Méa Plentz 19 Sarcopenia in Liver Disease: Current Evidence and Issues to Be Resolved ������������������������������������������������������������������������������������������ 413 Meiyi Song, Lu Xia, Qi Liu, Mengxue Sun, Fei Wang, and Changqing Yang Contents vii Part V Diagnosis, Drugs and Promising Agents of Muscle Atrophy 20 Muscle Atrophy Measurement as Assessment Method for Low Back Pain Patients . 437 Elżbieta Skorupska 21 Drugs of Muscle Wasting and Their Therapeutic Targets . 463 Kunihiro Sakuma and Akihiko Yamaguchi 22 Nutritional Support to Counteract Muscle Atrophy ���������������������������� 483 Daniel John Owens 23 Nutritional Considerations in Preventing Muscle Atrophy. 497 Sanda Maria Cretoiu and Corina Aurelia Zugravu 24 Physical Exercise for Muscle Atrophy ���������������������������������������������������� 529 Liang Shen, Xiangmin Meng, Zhongrong Zhang, and Tianhui Wang Part VI Treatment Strategies of Muscle Atrophy 25 To Contrast and Reverse Skeletal Muscle Atrophy by Full-Body In-Bed Gym, a Mandatory Lifestyle for Older Olds and Borderline Mobility-Impaired Persons ������������������������������������������ 549 Ugo Carraro, Karma Gava, Alfonc Baba, Andrea Marcante, and Francesco Piccione 26 Overview of FES-Assisted Cycling Approaches and Their Benefits on Functional Rehabilitation and Muscle Atrophy . 561 Michelle Rabelo, Renata Viana Brigido de Moura Jucá, Lidiane Andréa Oliveira Lima, Henrique Resende-Martins, Antônio Padilha Lanari Bó, Charles Fattal, Christine Azevedo-Coste, and Emerson Fachin-Martins 27 To Reverse Atrophy of Human Muscles in Complete SCI Lower Motor Neuron Denervation by Home-Based Functional Electrical Stimulation ������������������������������������������������������������������������������ 585 Helmut Kern, Paolo Gargiulo, Amber Pond, Giovanna Albertin, Andrea Marcante, and Ugo Carraro 28 Preventing Muscle Atrophy Following Strokes: A Reappraisal . 593 Sunil Munakomi Part VII Future Prospects 29 Muscle Atrophy: Present and Future . 605 Richard Y. Cao, Jin Li, Qiying Dai, Qing Li, and Jian Yang Contributors Giovanna Albertin Section of Anatomy, Department of Neuroscience, University of Padova, Padova, Italy Guillermo Avila Department of Biochemistry, Cinvestav, México City, Mexico Christine Azevedo-Coste INRIA, Université de Montpellier, Montpellier, France Alfonc Baba IRCCS Fondazione Ospedale San Camillo, Venezia-Lido, Italy Antônio Padilha Lanari Bó NTAAI – Núcleo de Tecnologia Assistiva, Acessibilidade e Inovação, Campus de Ceilândia, Universidade de Brasília, Brasília, Brazil Electrical Engineering Department, Faculty of Technology, Universidade de Brasília, Brasília, Brazil Richard Y. Cao Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China Shanghai Clinical Research Center, Chinese Academy of Sciences, Shanghai, China Ugo Carraro IRCCS Fondazione Ospedale San Camillo, Venezia-Lido, Italy Interdepartmental Research Center of Myology (CIR-Myo), Department of Biomedical Science, University of Padova, Padova, Italy A&C M-C Foundation for Translational Myology, Padova, Italy Dragos Cretoiu Alessandrescu-Rusescu National Institute of Mother and Child Health, Fetal Medicine Excellence Research Center Bucharest, Bucharest, Romania Division of Cell and Molecular Biology and Histology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania Sanda Maria Cretoiu Division of Cell and Molecular Biology and Histology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania Qiying Dai Metrowest Medical Center, Framingham, MA, USA Department of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China ix x Contributors Gabriel Ribeiro de Freitas Programa de Pós-Graduação em Fisioterapia (PPGFt), Departamento de Fisioterapia, Centro de Ciências da Saúde e do Esporte (CEFID), Universidade do Estado de Santa Catarina (UDESC), Florianópolis, Santa Catarina, Brazil Renata Viana Brigido de Moura Jucá NTAAI – Núcleo de Tecnologia Assistiva, Acessibilidade e Inovação, Campus de Ceilândia, Universidade de Brasília, Brasília, Brazil Physical Therapy Department, Universidade Federal do Ceará, Fortaleza, Brazil Shengguang Ding Department of Thoracic and
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