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Method for Producing Methacrylic Acid And/Or Ester Thereof
(19) TZZ _T (11) EP 2 894 224 A1 (12) EUROPEAN PATENT APPLICATION published in accordance with Art. 153(4) EPC (43) Date of publication: (51) Int Cl.: 15.07.2015 Bulletin 2015/29 C12P 7/62 (2006.01) C12N 15/09 (2006.01) (21) Application number: 13835104.4 (86) International application number: PCT/JP2013/005359 (22) Date of filing: 10.09.2013 (87) International publication number: WO 2014/038216 (13.03.2014 Gazette 2014/11) (84) Designated Contracting States: (72) Inventors: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB • SATO, Eiji GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO Yokohama-shi PL PT RO RS SE SI SK SM TR Kanagawa 227-8502 (JP) Designated Extension States: • YAMAZAKI, Michiko BA ME Yokohama-shi Kanagawa 227-8502 (JP) (30) Priority: 10.09.2012 JP 2012198840 • NAKAJIMA, Eiji 10.09.2012 JP 2012198841 Yokohama-shi 31.01.2013 JP 2013016947 Kanagawa 227-8502 (JP) 30.07.2013 JP 2013157306 • YU, Fujio 01.08.2013 JP 2013160301 Yokohama-shi 01.08.2013 JP 2013160300 Kanagawa 227-8502 (JP) 20.08.2013 JP 2013170404 • FUJITA, Toshio Yokohama-shi (83) Declaration under Rule 32(1) EPC (expert Kanagawa 227-8502 (JP) solution) • MIZUNASHI, Wataru Yokohama-shi (71) Applicant: Mitsubishi Rayon Co., Ltd. Kanagawa 227-8502 (JP) Tokyo 100-8253 (JP) (74) Representative: Hoffmann Eitle Patent- und Rechtsanwälte PartmbB Arabellastraße 30 81925 München (DE) (54) METHOD FOR PRODUCING METHACRYLIC ACID AND/OR ESTER THEREOF (57) To provide a method for directly and efficiently producing methacrylic acid in a single step from renew- able raw materials and/or biomass arising from the utili- zation of the renewable raw materials. -
UCC Library and UCC Researchers Have Made This Item Openly Available. Please Let Us Know How This Has Helped You. Thanks! Downlo
UCC Library and UCC researchers have made this item openly available. Please let us know how this has helped you. Thanks! Title Bacterial inhabitants of tumours: methods for exploration and exploitation Author(s) Walker, Sidney P. Publication date 2020-05-04 Original citation Walker, S. P. 2020. Bacterial inhabitants of tumours: methods for exploration and exploitation. PhD Thesis, University College Cork. Type of publication Doctoral thesis Rights © 2020, Sidney P. Walker. https://creativecommons.org/licenses/by-nc-nd/4.0/ Item downloaded http://hdl.handle.net/10468/10055 from Downloaded on 2021-10-08T08:21:36Z Coláiste na hOllscoile, Corcaigh THE NATIONAL UNIVERSITY OF IRELAND, CORK School of Microbiology Bacterial inhabitants of tumours: Methods for exploration and exploitation Thesis presented by Sidney Walker Under the supervision of Dr. Mark Tangney and Dr. Marcus Claesson For the degree of Doctor of Philosophy 2016-2020 1 Contents Abstract .................................................................................................................................................. 3 Chapter I: Literature Review .............................................................................................................. 7 Section 1: Sequencing and the Microbiome ........................................................................ 7 The Microbiome ............................................................................................................... 8 Sequencing .................................................................................................................... -
Effect of Vertical Flow Exchange on Microbial Community Dis- Tributions in Hyporheic Zones
Article 1 by Heejung Kim and Kang-Kun Lee* Effect of vertical flow exchange on microbial community dis- tributions in hyporheic zones School of Earth and Environmental Sciences, Seoul National University, Seoul 08826, Republic of Korea; *Corresponding author, E-mail: [email protected] (Received: November 2, 2018; Revised accepted: January 6, 2019) https://doi.org/10.18814/epiiugs/2019/019001 The effect of the vertical flow direction of hyporheic flux advance of hydrodynamic modeling has improved research of hydro- on the bacterial community is examined. Vertical velocity logical exchange processes at the hyporheic zone (Cardenas and Wil- change of the hyporheic zone was examined by installing son, 2007; Fleckenstein et al., 2010; Endreny et al., 2011). Also, this a piezometer on the site, and a total of 20,242 reads were zone has plentiful micro-organisms. The hyporheic zone constituents analyzed using a pyrosequencing assay to investigate the a dynamic hotspot (ecotone) where groundwater and surface water diversity of bacterial communities. Proteobacteria (55.1%) mix (Smith et al., 2008). were dominant in the hyporheic zone, and Bacteroidetes This area constitutes a flow path along which surface water down wells into the streambed sediment and groundwater up wells in the (16.5%), Actinobacteria (7.1%) and other bacteria phylum stream, travels for some distance before eventually mixing with (Firmicutes, Cyanobacteria, Chloroflexi, Planctomycetesm groundwater returns to the stream channel (Hassan et al., 2015). Sur- and unclassified phylum OD1) were identified. Also, the face water enters the hyporheic zone when the vertical hydraulic head hyporheic zone was divided into 3 points – down welling of surface water is greater than the groundwater (down welling). -
Phenotypic and Microbial Influences on Dairy Heifer Fertility and Calf Gut Microbial Development
Phenotypic and microbial influences on dairy heifer fertility and calf gut microbial development Connor E. Owens Dissertation submitted to the faculty of the Virginia Polytechnic Institute and State University in partial fulfillment of the requirements for the degree of Doctor of Philosophy In Animal Science, Dairy Rebecca R. Cockrum Kristy M. Daniels Alan Ealy Katharine F. Knowlton September 17, 2020 Blacksburg, VA Keywords: microbiome, fertility, inoculation Phenotypic and microbial influences on dairy heifer fertility and calf gut microbial development Connor E. Owens ABSTRACT (Academic) Pregnancy loss and calf death can cost dairy producers more than $230 million annually. While methods involving nutrition, climate, and health management to mitigate pregnancy loss and calf death have been developed, one potential influence that has not been well examined is the reproductive microbiome. I hypothesized that the microbiome of the reproductive tract would influence heifer fertility and calf gut microbial development. The objectives of this dissertation were: 1) to examine differences in phenotypes related to reproductive physiology in virgin Holstein heifers based on outcome of first insemination, 2) to characterize the uterine microbiome of virgin Holstein heifers before insemination and examine associations between uterine microbial composition and fertility related phenotypes, insemination outcome, and season of breeding, and 3) to characterize the various maternal and calf fecal microbiomes and predicted metagenomes during peri-partum and post-partum periods and examine the influence of the maternal microbiome on calf gut development during the pre-weaning phase. In the first experiment, virgin Holstein heifers (n = 52) were enrolled over 12 periods, on period per month. On -3 d before insemination, heifers were weighed and the uterus was flushed. -
Abstract Daughtry, Katheryne Virginia
ABSTRACT DAUGHTRY, KATHERYNE VIRGINIA. Phenotypic and Genotypic Characterization of Lactobacillus buchneri Strains Isolated from Spoiled Fermented Cucumber. (Under the direction of Dr. Rodolphe Barrangou and Dr. Suzanne D. Johanningsmeier). Lactobacillus buchneri is a facultative anaerobe and member of the lactic acid bacteria. L. buchneri has been isolated from various environments, but most commonly from decomposing plant material, such as silage and spoiled food products, including wine, beer, Swiss cheese, mayonnaise, and fermented cucumber. Recently, the metabolic pathway for the conversion of lactic acid to acetic acid and 1,2-propanediol was annotated in this species. Although this metabolic pathway is not common in most lactic acid bacteria, L. buchneri degrades lactate under various conditions. Lactic acid utilization in fermented cucumbers leads to a rise in pH, ultimately spoiling the product. In previous studies, strains of L. buchneri isolated from fermented cucumber spoiled displayed variation in colony morphologies. It was predicted the isolates were phenotypically and genotypically diverse, and that the abilities to degrade lactic acid may be strain specific. To examine this hypothesis, thirty-five L. buchneri cultures isolated from spoiled fermented cucumber and the type strain isolated from tomato pulp were characterized and unique strains were subjected to whole genome sequencing. Each isolate was genotypically and phenotypically characterized using 16S rDNA sequencing, DiversiLab® rep-PCR, colony morphology on MRS agar, carbohydrate profiling, growth rates in MRS media, and the ability to degrade lactic acid in a modified MRS medium. Great diversity in colony morphology revealed variations of color (ranging from opaque yellow to white), texture (brittle, viscous, or powdery), shape (umbonate, flat, circular, or irregular) and size (1 mm- 11mm). -
Molecular Mechanisms of Inhibition of Streptococcus Species by Phytochemicals
molecules Review Molecular Mechanisms of Inhibition of Streptococcus Species by Phytochemicals Soheila Abachi 1, Song Lee 2 and H. P. Vasantha Rupasinghe 1,* 1 Faculty of Agriculture, Dalhousie University, Truro, NS PO Box 550, Canada; [email protected] 2 Faculty of Dentistry, Dalhousie University, Halifax, NS PO Box 15000, Canada; [email protected] * Correspondence: [email protected]; Tel.: +1-902-893-6623 Academic Editors: Maurizio Battino, Etsuo Niki and José L. Quiles Received: 7 January 2016 ; Accepted: 6 February 2016 ; Published: 17 February 2016 Abstract: This review paper summarizes the antibacterial effects of phytochemicals of various medicinal plants against pathogenic and cariogenic streptococcal species. The information suggests that these phytochemicals have potential as alternatives to the classical antibiotics currently used for the treatment of streptococcal infections. The phytochemicals demonstrate direct bactericidal or bacteriostatic effects, such as: (i) prevention of bacterial adherence to mucosal surfaces of the pharynx, skin, and teeth surface; (ii) inhibition of glycolytic enzymes and pH drop; (iii) reduction of biofilm and plaque formation; and (iv) cell surface hydrophobicity. Collectively, findings from numerous studies suggest that phytochemicals could be used as drugs for elimination of infections with minimal side effects. Keywords: streptococci; biofilm; adherence; phytochemical; quorum sensing; S. mutans; S. pyogenes; S. agalactiae; S. pneumoniae 1. Introduction The aim of this review is to summarize the current knowledge of the antimicrobial activity of naturally occurring molecules isolated from plants against Streptococcus species, focusing on their mechanisms of action. This review will highlight the phytochemicals that could be used as alternatives or enhancements to current antibiotic treatments for Streptococcus species. -
Probiotic Dairy Products Society of Dairy Technology Series
Probiotic Dairy Products Society of Dairy Technology Series Series Editor: Adnan Y. Tamime The Society of Dairy Technology has joined with Wiley‐Blackwell to produce a series of technical dairy‐related handbooks providing an invaluable resource for all those involved in the dairy industry; from practitioners to technologists working in both tradi- tional and modern large‐scale dairy operations. Probiotic Dairy Products, 2nd Edition, ISBN 9781119214106 by Adnan Y. Tamime and Linda V. Thomas (Editors) Microbial Toxins in Dairy Products, ISBN 9781118756430 by Adnan Y. Tamime (Editor) Biofilms in the Dairy Industry, ISBN 9781118876213 by Koon Hoong Teh, Steve Flint, John Brooks, and Geoff Knight (Editors) Milk and Dairy Products as Functional Foods, ISBN 9781444336832 by Ara Kanekanian (Editor) Membrane Processing: Dairy and Beverage Applications, ISBN 9781444333374 by Adnan Y. Tamime (Editor) Processed Cheese and Analogues, ISBN 9781405186421 by Adnan Y. Tamime (Editor) Technology of Cheesemaking, 2nd Edition, ISBN 9781405182980 by Barry A. Law and Adnan Y. Tamime (Editors) Dairy Fats and Related Products, ISBN 9781405150903 by Adnan Y. Tamime (Editor) Dairy Powders and Concentrated Products, ISBN 9781405157643 by Adnan Y. Tamime (Editor) Milk Processing and Quality Management, ISBN 9781405145305 by Adnan Y. Tamime (Editor) Cleaning‐in‐Place: Dairy, Food and Beverage Operations, 3rd Edition, ISBN 9781405155038 by Adnan Y. Tamime (Editor) Structure of Dairy Products, ISBN 9781405129756 by Adnan Y. Tamime (Editor) Brined Cheeses, ISBN 9781405124607 by Adnan Y. Tamime (Editor) Fermented Milks, ISBN 9780632064588 by Adnan Y. Tamime (Editor) Probiotic Dairy Products, ISBN 9781405121248 by Adnan Y. Tamime (Editor) Probiotic Dairy Products Second Edition Edited by Adnan Y. -
The Bacterial Communities of Sand-Like Surface Soils of the San Rafael Swell (Utah, USA) and the Desert of Maine (USA) Yang Wang
The bacterial communities of sand-like surface soils of the San Rafael Swell (Utah, USA) and the Desert of Maine (USA) Yang Wang To cite this version: Yang Wang. The bacterial communities of sand-like surface soils of the San Rafael Swell (Utah, USA) and the Desert of Maine (USA). Agricultural sciences. Université Paris-Saclay, 2015. English. NNT : 2015SACLS120. tel-01261518 HAL Id: tel-01261518 https://tel.archives-ouvertes.fr/tel-01261518 Submitted on 25 Jan 2016 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. NNT : 2015SACLS120 THESE DE DOCTORAT DE L’UNIVERSITE PARIS-SACLAY, préparée à l’Université Paris-Sud ÉCOLE DOCTORALE N°577 Structure et Dynamique des Systèmes Vivants Spécialité de doctorat : Sciences de la Vie et de la Santé Par Mme Yang WANG The bacterial communities of sand-like surface soils of the San Rafael Swell (Utah, USA) and the Desert of Maine (USA) Thèse présentée et soutenue à Orsay, le 23 Novembre 2015 Composition du Jury : Mme. Marie-Claire Lett , Professeure, Université Strasbourg, Rapporteur Mme. Corinne Cassier-Chauvat , Directeur de Recherche, CEA, Rapporteur M. Armel Guyonvarch, Professeur, Université Paris-Sud, Président du Jury M. -
Microbiology in Shale: Alternatives for Enhanced Gas Recovery
Graduate Theses, Dissertations, and Problem Reports 2015 Microbiology in Shale: Alternatives for Enhanced Gas Recovery Yael Tarlovsky Tucker Follow this and additional works at: https://researchrepository.wvu.edu/etd Recommended Citation Tucker, Yael Tarlovsky, "Microbiology in Shale: Alternatives for Enhanced Gas Recovery" (2015). Graduate Theses, Dissertations, and Problem Reports. 6834. https://researchrepository.wvu.edu/etd/6834 This Dissertation is protected by copyright and/or related rights. It has been brought to you by the The Research Repository @ WVU with permission from the rights-holder(s). You are free to use this Dissertation in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you must obtain permission from the rights-holder(s) directly, unless additional rights are indicated by a Creative Commons license in the record and/ or on the work itself. This Dissertation has been accepted for inclusion in WVU Graduate Theses, Dissertations, and Problem Reports collection by an authorized administrator of The Research Repository @ WVU. For more information, please contact [email protected]. Microbiology in Shale: Alternatives for Enhanced Gas Recovery Yael Tarlovsky Tucker Dissertation submitted to the Davis College of Agriculture, Natural Resources and Design at West Virginia University in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Genetics and Developmental Biology Jianbo Yao, Ph.D., Chair James Kotcon, Ph.D. -
United States Patent (10) Patent No.: US 7820,184 B2 Stritzker Et Al
USOO782O184B2 (12) United States Patent (10) Patent No.: US 7820,184 B2 Stritzker et al. (45) Date of Patent: Oct. 26, 2010 (54) METHODS AND COMPOSITIONS FOR 5,833,975 A 1 1/1998 Paoletti et al. ............. 424.93.2 DETECTION OF MICROORGANISMS AND 5,976,796. A 1 1/1999 Szalay et al. ................... 435/6 SirNRTREATMENT OF DISEASES AND 6,025,155 A 2/2000 Hadlaczky et al. ......... 435/69.1 6,045,802 A 4/2000 Schlom et al. ........... 424,199.1 (75) Inventors: Jochen Harald Stritzker, Kissing (DE); 6,077,697 A 6/2000 Hadlaczky et al. 435/1723 Phil Hill, West Bridgford (GB); Aladar 6,080,849 A 6/2000 Bermudes et al. .......... 536,23.7 A. Szalay, Highland, CA (US); Yong A. 6,093,700 A 7/2000 Mastrangelo et al. ......... 514,44 Yu, San Diego, CA (US) 6,099,848. A 8/2000 Frankel et al. ........... 424,246.1 6,106,826 A 8/2000 Brandt et al. .............. 424.93.2 (73) Assignee: stylus Corporation, San Diego, CA 6, 190,657 B1 2/2001 Pawelek et al. ............ 424,931 6,217,847 B1 4/2001 Contaget al. ................ 4249.1 (*) Notice: Subject to any disclaimer, the term of this 6,232,523 B1 5/2001 Tan et al. ...................... 800, 10 patent is extended or adjusted under 35 6,235,967 B1 5/2001 Tan et al. ...................... 800, 10 U.S.C. 154(b) by 362 days. 6,235,968 B1 5/2001 Tan et al. ...................... 800, 10 6,251,384 B1 6/2001 Tan et al. -
Variation of the Frog Skin Microbiota Across an Environmental Gradient: Taxonomic Diversity and Potential Function
VARIATION OF THE FROG SKIN MICROBIOTA ACROSS AN ENVIRONMENTAL GRADIENT: TAXONOMIC DIVERSITY AND POTENTIAL FUNCTION Brandon J. Varela Department of Biology, Neotropical Environment Option McGill University, Montreal August, 2017 A thesis submitted to McGill University in partial fulfillment of the requirements of the degree of Master’s in Science in Biology Brandon J. Varela, 2017 1 TABLE OF CONTENTS ABSTRACT .............................................................................................................. 4 RÉSUMÉ .................................................................................................................. 5 ACKNOWLEDGEMENTS ...................................................................................... 7 CONTRIBUTIONS OF AUTHORS ......................................................................... 9 Introduction ............................................................................................................ 10 Thesis objectives ......................................................................................................................... 14 Hypothesis 1 ........................................................................................................................................ 15 Hypothesis 2 ........................................................................................................................................ 15 Hypothesis 3 ....................................................................................................................................... -
1 Supplementary Material a Major Clade of Prokaryotes with Ancient
Supplementary Material A major clade of prokaryotes with ancient adaptations to life on land Fabia U. Battistuzzi and S. Blair Hedges Data assembly and phylogenetic analyses Protein data set: Amino acid sequences of 25 protein-coding genes (“proteins”) were concatenated in an alignment of 18,586 amino acid sites and 283 species. These proteins included: 15 ribosomal proteins (RPL1, 2, 3, 5, 6, 11, 13, 16; RPS2, 3, 4, 5, 7, 9, 11), four genes (RNA polymerase alpha, beta, and gamma subunits, Transcription antitermination factor NusG) from the functional category of Transcription, three proteins (Elongation factor G, Elongation factor Tu, Translation initiation factor IF2) of the Translation, Ribosomal Structure and Biogenesis functional category, one protein (DNA polymerase III, beta subunit) of the DNA Replication, Recombination and repair category, one protein (Preprotein translocase SecY) of the Cell Motility and Secretion category, and one protein (O-sialoglycoprotein endopeptidase) of the Posttranslational Modification, Protein Turnover, Chaperones category, as annotated in the Cluster of Orthologous Groups (COG) (Tatusov et al. 2001). After removal of multiple strains of the same species, GBlocks 0.91b (Castresana 2000) was applied to each protein in the concatenation to delete poorly aligned sites (i.e., sites with gaps in more than 50% of the species and conserved in less than 50% of the species) with the following parameters: minimum number of sequences for a conserved position: 110, minimum number of sequences for a flank position: 110, maximum number of contiguous non-conserved positions: 32000, allowed gap positions: with half. The signal-to-noise ratio was determined by altering the “minimum length of a block” parameter.