DOCSLIB.ORG

September | 2013 ISSN 1660-3656 Epileptologie | 30. Jahrgang

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
September | 2013 ISSN 1660-3656 Epileptologie | 30. Jahrgang Epileptologie | 30. Jahrgang September | 2013 ISSN 1660-3656 Epilepsie-Liga Seefeldstrasse 84 Postfach 1084 CH-8034 Zürich Redaktionskommission Thomas Dorn | Zürich Reinhard E. Ganz | Zürich Martinus Hauf | Tschugg Hennric Jokeit | Zürich Christian M. Korff | Genève Günter Krämer | Zürich (Vorsitz) Inhalt Oliver Maier | St. Gallen Andrea O. Rossetti | Lausanne Stephan Rüegg | Basel Kaspar Schindler | Bern Editorial 147 – 149 Serge Vulliémoz | Genève Combination of Electroencephalographic and Magnetic Resonance Imaging to Beirat Characterize Epileptic Networks Christoph M. Michel 150 – 157 Alexandre Datta | Basel Thomas Grunwald | Zürich Structure, Function and Genes: Christian W. Hess | Bern What Can We Learn from MRI Anna Marie Hew-Winzeler | Zürich Giorgi Kuchukhidze, Eugen Trinka 158 – 166 Günter Krämer | Zürich Theodor Landis | Genève Hereditäre epileptische Enzephalopathie Malin Maeder | Lavigny mit Amelogenesis imperfecta Klaus Meyer | Tschugg Kohlschütter-Tönz-Syndrom Christoph Michel | Genève (KTZS). Bericht über einen weiteren, Christoph Pachlatko | Zürich posthum erfassten Patienten aus der Monika Raimondi | Lugano Zentralschweiz. Andrea O. Rossetti | Lausanne Otmar Tönz, Bernhard Steiner, Anna Stephan Rüegg | Basel Schossig, Johannes Zschocke, Markus Schmutz | Basel Alfried Kohlschütter 167– 174 Margitta Seeck | Genève Urs Sennhauser | Hettlingen Epilepsie-Liga-Mitteilungen 175 – 198 Franco Vassella | Bremgarten Kongresskalender 199 – 200 Schweizerische Liga gegen Epilepsie Ligue Suisse contre l’Epilepsie Lega Svizzera contro l’Epilessia Swiss League Against Epilepsy Richtlinien für die Autoren Allgemeines - Zusammenfassung, Résumé und englischer Ab- stract (mit Titel der Arbeit): Ohne Literaturzitate Epileptologie veröffentlicht sowohl angeforderte als und Akronyme sowie unübliche Abkürzungen (je auch unaufgefordert eingereichte Manuskripte über maximal 250 Wörter). alle Themen der Epileptologie. Es werden in der Regel - Text: Dabei bei Originalarbeiten Gliederung in Ein- nur bislang unveröffentlichte Arbeiten angenommen. leitung, Methode (inkl. Untersuchungsmaterial, Pa- Die Manuskripte oder wesentliche Teile daraus dürfen tienten, Versuchstiere etc., ggf. auch Angabe über auch nicht gleichzeitig anderen Zeitschriften angebo- Einwilligung bzw. Einhaltung der Deklaration von ten werden oder anderweitig bereits zur Publikation Helsinki inkl. Votum einer Ethikkommission), Ergeb- angenommen worden sein. Alle Manuskripte werden nisse und Diskussion. Abkürzungen sind bei ihrem zweifach begutachtet. Von den Beiträgen werden keine ersten Erscheinen im Text voll auszuschreiben. Sonderdrucke erstellt, sie werden jedoch als pdf-Datei - Literaturverzeichnis: Am Ende der Arbeit werden die zusätzlich auf der Liga-Homepage (www.epi.ch) veröf- Literaturstellen in der im Text zitierten Reihenfolge fentlicht und können von dort heruntergeladen wer- aufgeführt und nach untenstehendem Muster zi- den. tiert. Persönliche Mitteilungen, unveröffentlichte Befunde oder zur Publikation eingereichte Manu- Redaktionsanschrift skripte werden nicht aufgenommen, sondern ent- sprechend im Text vermerkt. Zitierungen „im Druck“ Unaufgefordert eingereichte Manuskripte (inkl. bzw. „in press“ beziehen sich nur auf von einer Zeit- Briefe an die Herausgeber) sind zu richten an: Frau M. schrift bereits angenommene Arbeiten (mit Angabe Becker, Redaktion Epileptologie, Schweizerische Liga von Zeitschrift und – soweit bekannt – Band und gegen Epilepsie, Seefeldstr. 84, Postfach 1084, 8034 Erscheinungsjahr. Das Zitieren von Arbeiten als „in Zürich. Tel. 043 488 67 79, Fax 043 488 67 78, e-mail: Vorbereitung“ oder „in preparation“ ist nicht zuläs- [email protected]. sig. Kongressmitteilungen können nur als zitierbare Abstracts oder Beitrag in Proceedings-Bänden be- Hinweise zur Manuskripterstellung rücksichtigt werden. - Tabellen: Jede Tabelle steht auf einer neuen Seite Manuskripte werden nur akzeptiert, wenn sie den und hat eine kurze erklärende Überschrift. Abkür- folgenden Kriterien entsprechen. Nicht entsprechend zungen oder Zeichen sind in einer Fussnote zu erklä- abgefasste Manuskripte werden vor der Begutachtung ren. zurückgesandt. - Abbildungslegenden: Die Legende für jede Abbil- 1. Sprache: Neben deutsch auch englisch und franzö- dung steht auf einer neuen Seite; alle Abkürzungen sisch möglich. oder Zeichen sind darin zu erklären. 2. Schreibweise (deutsch): Als Schreibweise gilt die - Abbildungen: Strichzeichnungen, schattierte Zeich- deutsche Form mit „z“ und „k“ (also z.B. Karzinom), nungen oder Fotografien (SW oder Farbe). lateinische Fachtermini behalten aber ihre Schreib- - Zitierweise: Zeitschriftenartikel: Daoud AS, Batie- weise (also z. B. Arteria carotis). ha A, Abu-Ekteish F et al. Iron status: a possible risk 3. Form: Der gesamte Text, einschliesslich Literaturver- factor for the first febrile seizure. Epilepsia 2002; zeichnis, Tabellen und Abbildungslegenden, ist fol- 43: 740-743 (bei bis zu vier Autoren werden alle ge- gendermassen zu formatieren: nannt; Abkürzungen der Zeitschriften nach der „List - DIN-A4-Papier, einseitig (1 1/2- oder 2-zeilig mit of Journals indexed in Index Medicus“); Bücher: max. 30 Zeilen je Seite). Shorvon S. Status Epilepticus. Its Clinical Features - Literaturverweise werden gemäss der Reihenfolge, and Treatment in Children and Adults. Cambridge: in der sie im Text vorkommen, arabisch nummeriert; Cambridge University Press, 1994; Buchkapitel: im Text erscheinen die Verweiszahlen in eckigen Holthausen H, Tuxhorn I, Pieper T et al. Hemis- Klammern. pherectomy in the treatment of neuronal migrati- - Tabellen und Abbildungen haben eine jeweils fort- onal disorders. In: Kotagal P, Lüders HO (eds): The laufende arabische Nummerierung. Epilepsies. Etiologies and Prevention. San Diego, 4. Reihenfolge: 1. Titelblatt (ggf. inkl. Danksagung, För- London, Boston et al.: Academic Press, 1999: 93-102 derung durch Hilfe anderer oder Drittmittelfinanzie- rung), 2. Zusammenfassung in Deutsch, Résumé in Was ist an die Redaktion einzureichen? Französisch und Summary in Englisch sowie je drei bis fünf Schlüsselwörter, 3. Text, 4. Literatur, 5. Ta- Alle Manuskripte sind inklusive Abbildungen und bellen, 6. Abbildungslegenden und 7. Abbildungen: Tabellen in dreifacher Ausführung einzureichen. Bevor- - Das Titelblatt enthält den vollen Titel der Arbeit zugt wird eine elektronische Manuskripteinreichung (deutsch und englisch), Namen und Titel der Auto- per e-mail (Textverarbeitung: MS Word), alternativ die ren, die Kliniken bzw. Institutionen, an denen alle Zusendung von drei Ausdrucken und einer Diskette (für Autoren arbeiten, sowie die vollständige Adresse Abb. und Tab. ist das verwendete Programm anzuge- des federführenden Autors mit Telefon- und Fax- ben). nummer sowie e-mail. Editorial Dr. med. Günter Krämer Giorgi Kuchukhidze und Eugen Trinka aus Salz- burg widmen sich dem spannenden Thema, worin der Beitrag der Bildgebung in der Diagnostik kortikaler Malformationen besteht, dies insbesondere auch in Verbindung mit neuesten genetischen Daten. Es zeigt sich immer mehr, dass verschiedene Mutationen eines Gens zu einem breiten Fehlbildungsspektrum führen können, und dass sich die Grenzen zwischen Störungen der Proliferation, Migration und Differenzierung verwi- schen. Der Beitrag von Professor Otmar Tönz zusammen mit seinen Co-Autoren (u.a. Professor Alfried Kohlschüt- Das vorliegende Heft der Epileptologie fällt aus ter aus Hamburg) bezieht sich auf das von ihnen erst- mehreren Gründen etwas aus dem üblichen Rahmen. mals 1974 bei einer Schweizer Familie beschriebene, Nachdem ich relativ kurzfristig für ein anderes Mitglied autosomal-rezessiv hereditäre epileptische Enzepha- der Redaktionskommission die Aufgabe übernehmen lopathie-Syndrom mit Epilepsie, Demenz und gelben musste, ein Heft zu koordinieren, lag es für mich nahe, Zähnen. In den letzten Jahren wurde auch die Genetik dies mit der erneut – sowohl wissenschaftlich als auch dieses seltenen Syndroms weitgehend aufgeklärt. Die finanziell – erfolgreichen Epilepsie-Dreiländertagung vorgestellte Krankengeschichte ist u.a. insofern bemer- zusammen mit den Deutschen und Österreichischen kenswert, weil der Patient von den Autoren schon vor Gesellschaften für Epilepsie Mitte Mai in Interlaken zu ihrer Erstbeschreibung beobachtet worden war und er verbinden. mit 37 Jahren ein für dieses Syndrom vergleichsweise Was lag näher, als die Referenten des Präsidenten- hohes Alter erreichte. Beide Eltern waren Träger der Symposiums mit jeweils einem Beitrag aus den drei Mutation im RODGI-Gen. Ländern zu bitten, ihre Vorträge als Manuskript einzu- Schliesslich erlaube ich mir auch noch den Hin- reichen. Erfreulicherweise sagten auch alle drei Refe- weis auf die in diesem Heft abgedruckten zahlreichen renten zu, letztendlich konnte der Beitrag aus Deutsch- Laudationes anlässlich der Dreiländertagung in Inter- land aber nicht fristgerecht erstellt werden. Den des- laken. Dies betrifft die Vergabe der Tissot-Medaille an wegen zur Verfügung stehenden Raum konnten wir für Professor Giuseppe Scollo-Lavizzari aus Basel, des For- ein eingereichtes Manuskript mit Langzeit-Daten zu schungsförderungspreises an PD Jean-Yves Chatton aus einem erstmals in der Schweiz beschriebenen seltenen Lausanne und Dr. Benjamin Stöcklin aus Basel, des Pro- Epilepsiesyndrom zur Verfügung stellen. Lassen Sie motionspreises an Frau Dr. Sarah Broicher aus Zürich, mich die Beiträge kurz kommentieren. des Alfred-Hauptmann-Preises an Frau Professor Yvon- Christoph Michel berichtet über die jahrelangen ne Weber aus Tübingen
Load more

Recommended publications
  • Therapeutic Class Overview Anticonvulsants
    Therapeutic Class Overview Anticonvulsants INTRODUCTION Epilepsy is a disease of the brain defined by any of the following (Fisher et al 2014): ○ At least 2 unprovoked (or reflex) seizures occurring > 24 hours apart; ○ 1 unprovoked (or reflex) seizure and a probability of further seizures similar to the general recurrence risk (at least 60%) after 2 unprovoked seizures, occurring over the next 10 years; ○ Diagnosis of an epilepsy syndrome. Types of seizures include generalized seizures, focal (partial) seizures, and status epilepticus (Centers for Disease Control and Prevention [CDC] 2018, Epilepsy Foundation 2016). ○ Generalized seizures affect both sides of the brain and include: . Tonic-clonic (grand mal): begin with stiffening of the limbs, followed by jerking of the limbs and face . Myoclonic: characterized by rapid, brief contractions of body muscles, usually on both sides of the body at the same time . Atonic: characterized by abrupt loss of muscle tone; they are also called drop attacks or akinetic seizures and can result in injury due to falls . Absence (petit mal): characterized by brief lapses of awareness, sometimes with staring, that begin and end abruptly; they are more common in children than adults and may be accompanied by brief myoclonic jerking of the eyelids or facial muscles, a loss of muscle tone, or automatisms. ○ Focal seizures are located in just 1 area of the brain and include: . Simple: affect a small part of the brain; can affect movement, sensations, and emotion, without a loss of consciousness . Complex: affect a larger area of the brain than simple focal seizures and the patient loses awareness; episodes typically begin with a blank stare, followed by chewing movements, picking at or fumbling with clothing, mumbling, and performing repeated unorganized movements or wandering; they may also be called “temporal lobe epilepsy” or “psychomotor epilepsy” .
    [Show full text]
  • Epilepsy and Communication
    fasic England Gloss ry Epilepsy and communication Epilepsy is a chronic disorder of the brain • Temporal Lobe epilepsy characterised by recurrent seizures, which affects • Dravet syndrome people worldwide (WHO, 2016). The World Health Organisation deKnes a seizure as a transient loss of There are a range of communication difficulties function of all or part of the brain due to excessive associated with epilepsy. For some people, electrical discharges in a group of brain cells. Physical, communication difficulties can become more sensory or other functions can be temporarily lost. pronounced at times immediately before, during or after seizure activity. Epilepsy affects 1 in 177 young people under the age of 25 so there are around 112,000 young people with Communication difficulties may include: epilepsy in the UK (Joint Epilepsy Council, 2011). In 75% • Comprehension difficulties: Children may Knd it of people, seizures are well controlled with medication hard to understand what others are saying to but 25% continue to have seizures despite treatment. them or what is expected of them, and may struggle to understand environmental cues, daily Epilepsy can be linked with learning, behavioural and routines or activity sequences. speech and language difficulties. This is increasingly • Attention and listening difficulties: Children recognised and the risks are greater if epilepsy occurs may have difficulties in attending to spoken before 2 years of age. Parkinson (1994) found that language, or to an activity. from a small study of children referred for assessment of their epilepsy, 40% had undiagnosed language • Expressive difficulties: It may be hard for impairment of varying degrees of severity.
    [Show full text]
  • 14582 IBE Newsletter 2003
    International Bureau for Epilepsy Annual Report 2003 Setting the Standard From Our Vision IBE has a vision of the world where everywhere ignorance and fear about epilepsy are replaced by understanding and care. Our Mission IBE exists to improve the social condition and quality of life of people with epilepsy and those who care for them. Our Goals • ORGANISATION To provide an international umbrella organisation for national epilepsy organisations whose primary purpose is to improve the social condition and quality of life of people with epilepsy and those who care for them. • SUPPORT To provide a strong global network to support the development of new Chapters, to support existing Chapters to develop to their fullest potential and to encourage co-operation and contact between Chapters. • COMMUNICATION To promote the facts about epilepsy and to communicate IBE’s vision, mission and messages to the widest possible audience. • EDUCATION To increase understanding and knowledge of epilepsy. • REPRESENTATION To provide an international and global platform for the representation of epilepsy. 2 International Bureau for Epilepsy Foreward During my fifteen years working, first in the British Parliament and Government and now in the European Parliament, I have seen and welcomed an ever-increasing awareness of the importance and benefits of strong partnerships. Networks and alliances are more than just “buzz words” – they are proven methods of achieving desired goals. They may not be easy to achieve, but, once in place, they make it simpler for patients, carers, professionals and academics to explain health needs and options for action and they make it easier for policy-makers to listen and to understand what is needed.
    [Show full text]
  • A Clinical Guide to Epileptic Syndromes and Their Treatment
    Published August 13, 2008 as 10.3174/ajnr.A1231 dures and principles of treatment. These chapters are particu- BOOK REVIEW larly important for readers unfamiliar with the overall clinical presentation of the epilepsies and their diagnostic evaluation. A Clinical Guide to Epileptic Omitting these topics was a certain pitfall that has been Syndromes and Their Treatment, avoided. Basic techniques used in the evaluation of patients with of epilepsy, including anatomic and functional neuroim- 2nd ed. aging, are also included. The discussion of the relative value of C.P. Panayiotopoulos, ed. London, UK: Springer-Verlag; 2007, 578 EEG and its problems is particularly valuable. pages, 100 illustrations, $99.00. Subsequent chapters are devoted to the meat of the book, the epilepsy syndromes. These are presented in age-based he syndromic classification of epileptic seizures has been chronologic order, beginning with syndromes in the neonate evolving for more than a quarter century. Piggy-backed T and infant and continuing through syndromes in adults. onto major advances in neurophysiology and neuroimaging, Complete coverage of reflex seizures and reflex epilepsies in the current nomenclature of specific clinical epilepsy syn- chapter 16 is particularly welcome. Chapter 17 covers a group dromes now supersedes earlier seizure classifications based of disorders that are associated with epileptic seizures. The exclusively on seizure types. The practice of epilepsy has thus chapter gives excellent coverage of these disorders but makes joined mainstream medicine through its newfound ability to no pretenses at being comprehensive. For example, coverage link the signs and symptoms of epilepsy with specific under- of important disorders with epilepsy such as the Wolf- lying disorders.
    [Show full text]
  • Best Practice Guidelines for Training
    Best practice guidelines for training professional carers in the administration of Buccal (Oromucosal) Midazolam for the treatment of prolonged and / or clusters of epileptic seizures in the community Safe & Effective | Kind & Caring | Exceeding Expectation Epilepsy Nurses Association (ESNA) June 2019 1. Foreword One of the most important components of epilepsy care is the pre-hospital community management of prolonged or repeated seizures, which, if untreated, can increase the risk of status epilepticus. Convulsive status epilepticus is a medical emergency requiring admission to hospital and has a mortality rate of up to 20 per cent. Effective management of seizures in the community in people at high risk of status epilepticus could significantly reduce mortality, morbidity and emergency health care utilisation. The Joint Epilepsy Council issued guidance until it was disbanded in 2015, leaving a vacuum in the review and update of clinical guidelines. Unfortunately, the clinical processes ensuring the safety and consistency of buccal midazolam usage demonstrates considerable heterogeneity. There are no current guidelines, standards or pathways to ensure the safety of all involved in the process i.e. patient, carer or professional. ESNA is an organisation principally formed by nurses with an interest in epilepsy. Most ESNA members support or complete training for buccal midazolam to ensure core competencies are up to date and patient safety is protected. ESNA is joined by the International League Against Epilepsy (British Chapter) and the Royal College of Psychiatrists (ID Faculty) as the other principal specialist clinical stakeholders with an interest to ensure governance in this complex care area is addressed robustly. ESNA has collaborated with the ILAE and the Royal College of Psychiatrists to produce updated buccal midazolam guidance.
    [Show full text]
  • Fenfluramine Hydrochloride for the Treatment of Seizures in Dravet Syndrome: a Randomised, Double-Blind, Placebo-Controlled Trial
    Articles Fenfluramine hydrochloride for the treatment of seizures in Dravet syndrome: a randomised, double-blind, placebo-controlled trial Lieven Lagae*, Joseph Sullivan*, Kelly Knupp, Linda Laux, Tilman Polster, Marina Nikanorova, Orrin Devinsky, J Helen Cross, Renzo Guerrini, Dinesh Talwar, Ian Miller, Gail Farfel, Bradley S Galer, Arnold Gammaitoni, Arun Mistry, Glenn Morrison, Michael Lock, Anupam Agarwal, Wyman W Lai, Berten Ceulemans, for the FAiRE DS Study Group Summary Background Dravet syndrome is a rare, treatment-resistant developmental epileptic encephalopathy characterised by Published Online multiple types of frequent, disabling seizures. Fenfluramine has been reported to have antiseizure activity in December 17, 2019 observational studies of photosensitive epilepsy and Dravet syndrome. The aim of the present study was to assess the https://doi.org/10.1016/ S0140-6736(19)32500-0 efficacy and safety of fenfluramine in patients with Dravet syndrome. See Online/Comment https://doi.org/10.1016/ Methods In this randomised, double-blind, placebo-controlled clinical trial, we enrolled children and young adults S0140-6736(19)31239-5 with Dravet syndrome. After a 6-week observation period to establish baseline monthly convulsive seizure *Contributed equally frequency (MCSF; convulsive seizures were defined as hemiclonic, tonic, clonic, tonic-atonic, generalised tonic- Department of Paediatric clonic, and focal with clearly observable motor signs), patients were randomly assigned through an interactive web Neurology, University of response system in a 1:1:1 ratio to placebo, fenfluramine 0·2 mg/kg per day, or fenfluramine 0·7 mg/kg per day, Leuven, Leuven, Belgium (Prof L Lagae MD); University of added to existing antiepileptic agents for 14 weeks.
    [Show full text]
  • September 2019 Research Quarterly
    THINK BIG RESEARCH Q UARTER LY ISSUE 11: SEPTEMBER 2019 MY SEIZURE GAUGE EPILEPSY LEARNING HEALTHCARE SYSTEM SUDEP INSTITUTE INNOVATOR SPOTLIGHT FOUNDATION AWARDEES IN THE NEWS WELCOME Every year, the Epilepsy Foundation hosts a leadership conference that brings together local Epilepsy Foundations to share best practices from the network. This year’s theme is “THINK BIG.” I love this theme as it perfectly captures our strategic planning approach. We think big, so that we can act big, to make meaningful change today that will bring hope for tomorrow. TO CELEBRATE THE THINK BIG THEME, we will be In 1997, Apple launched their Think Different campaign, devoting this fall issue to the ways that we are thinking which brought new life into a company that would go on big – from driving therapeutic innovations, to changing to help reshape how we interact with technology. The outcomes, and saving lives. On page 4, you can learn full text of the ad is below: about the exciting progress of the My Seizure Gauge team, an international consortium working together to create a seizure forecasting device that could assess “Here’s to the crazy ones. The misfits. The rebels. The the chance of seizures like a weather forecast. On page troublemakers. The round pegs in the square holes. The 6, you can learn about our leadership of the Epilepsy ones who see things differently. They’re not fond of rules Learning Healthcare System, a new model to transform and they have no respect for the status quo. You can the healthcare system. On page 7, you can learn more quote them, disagree with them, glorify or vilify them.
    [Show full text]
  • Neurodiagnostics Referral Form
    Kern Medical 1700 Mount Vernon Avenue Bakersfield, CA 93306 Fax: 661.862.4940 Neurodiagnostics Referral Form Patient Name (Last Name, First Name, Middle Initial) Date Gender □ Male □ Female Patient preferred language for healthcare communication Date of Birth Patient Home Telephone Patient Alternative Telephone Patient Home Address Patient insurance company and plan(s) Authorization Number: Referral Form: Referring Provider Name (Last Name, First Name, Middle Initial) Referring Provider Contact Telephone Referring Provider Fax Referring Provider Address Patient’s Primary Care Provider (Last Name, First Name, Middle Initial) Procedure Requested: □ Routine EEG (REEG) - 20 Minutes (95816) □ Extended EEG - 1-2 Hours (95813) □ Extended EEG Greater than 2 Hours (95713) □ Long-Term EEG Recording (95716) □ Long-Term Ambulatory (Outpatient) EEG Recording (95953) EMU or Critical Continuous EEG (CCEEG) Length of Monitoring (select one): □ 24 HR □ 48 HR □ 72 HR □ 96 HR □ 120 HR □ ________ HR *Please attach last progress note, history and physical, insurance cards, demographics, any associated imaging. Provider Signature Please fax referral form and records to 661.862.4940 NEURODIAGNOSTICS Kern Medical offers the following EEG and EMU services Indications for routine Indications of Ambulatory Indications of VEEG study in How to Refer Patients to EEG VEEG EMU the EMU • After new onset seizure Ambulatory • Determine whether spells • Referrals can be arranged electroencephalography are epileptic seizures (spell by calling the Kern Medical • For diagnosing
    [Show full text]
  • Epilepsy & My Child Toolkit
    Epilepsy & My Child Toolkit A Resource for Parents with a Newly Diagnosed Child 136EMC Epilepsy & My Child Toolkit A Resource for Parents with a Newly Diagnosed Child “Obstacles are the things we see when we take our eyes off our goals.” -Zig Ziglar EPILEPSY & MY CHILD TOOLKIT • TABLE OF CONTENTS Introduction Purpose .............................................................................................................................................5 How to Use This Toolkit ....................................................................................................................5 About Epilepsy What is Epilepsy? ..............................................................................................................................7 What is a Seizure? .............................................................................................................................8 Myths & Facts ...................................................................................................................................8 How is Epilepsy Diagnosed? ............................................................................................................9 How is Epilepsy Treated? ..................................................................................................................10 Managing Epilepsy How Can You Help Manage Your Child’s Care? ...............................................................................13 What Should You Do if Your Child has a Seizure? ............................................................................14
    [Show full text]
  • Epileptics Are Affected by Flashing Lights ~ Cutting-Edge Projects in 15 Countries Around Our Mission: Only the World in Their Search for a Cure
    The REAL Project Research & Epilepsy Awareness Shona Sulzbach What is Epilepsy: What to do if you see someone having a seizure: - Epilepsy is a neurological disorder that presents - Time the seizure. itself in the form of a seizure. - Remain calm - A person must have more than one seizure to be - Stay with the person until the seizure ends and diagnosed with epilepsy. they are fully awake. - Epilepsy does not discriminate and 1/26 people - Comfort the person as they regain full will develop a seizure disorder in their life. Consciousness. Types of Epilepsy: Only call 911 if: - There are two broad categories: generalized - The person has not had a seizure before. and focal. - The seizure lasts longer than 5 minutes. - Not all seizures present themselves with the loss - The person is hurt during the seizure. of consciousness and convulsions. - The seizure occurred in water. - Many seizure disorders include types of seizures - The person has difficulty walking or breathing where the person goes into “a trance”. after the seizure ends. What is CURE? - The person has another seizure just after the What Causes Epilepsy: - Citizens United for Research in Epilepsy (CURE) first - Genetics, brain injury or trauma, and/or is a nonprofit organization that works to One. structural changes (tumors, growths, nerve promote epilepsy research. damage). - It was founded in 1998 by Susan Axelrod and a DO NOT: - About half of all people diagnosed with epilepsy small group of parents of children with - Hold the person down or try to stop the seizure. do not know the cause. epilepsy. - Try to open/put anything in the person’s mouth.
    [Show full text]
  • A Rare Cause of Unexplained Abdominal Pain
    Open Access Case Report DOI: 10.7759/cureus.10120 Abdominal Epilepsy: A Rare Cause of Unexplained Abdominal Pain Anvesh Balabhadra 1 , Apoorva Malipeddi 2 , Niloufer Ali 3 , Raju Balabhadra 4 1. Department of Neurology, Gandhi Medical College and Hospital, Hyderabad, IND 2. Department of Internal Medicine, Gandhi Medical College and Hospital, Hyderabad, IND 3. Department of Neurology, Aster Prime Hospital, Hyderabad, IND 4. Department of Neurological Surgery, Aster Prime Hospital, Hyderabad, IND Corresponding author: Anvesh Balabhadra, [email protected] Abstract Abdominal epilepsy (AE) is a very rare diagnosis; it is considered to be a category of temporal lobe epilepsies and is more commonly a diagnosis of exclusion. Demographic presentation of AE is usually in the pediatric age group. However, there is recorded documentation of its occurrence even in adults. AE can present with unexplained, relentless, and recurrent gastrointestinal symptoms such as paroxysmal pain, nausea, bloating, and diarrhoea that improve with antiepileptic therapy. It is commonly linked with electroencephalography (EEG) changes in the temporal lobes along with symptoms that reflect the involvement of the central nervous system (CNS) such as altered consciousness, confusion, and lethargy. Due to the vague nature of these symptoms, there is a high chance of misdiagnosing a patient. We present the case of a 20-year-old man with AE who was misdiagnosed with psychogenic abdominal pain after undergoing multiple investigations with various hospital departments. Categories: Neurology, Gastroenterology, General Surgery Keywords: eeg, abdominal epilepsy, temporal lobe epilepsy, unexplained abdominal pain Introduction Abdominal epilepsy (AE) is a rare syndrome, even rarer when seen in adults and presents with paroxysmal symptoms favouring an abdominal pathology that result from seizure activity [1].
    [Show full text]
  • Initiating an Epilepsy Surgery Program with Limited Resources in Indonesia
    www.nature.com/scientificreports OPEN Initiating an epilepsy surgery program with limited resources in Indonesia Muhamad Thohar Arifn1*, Ryosuke Hanaya2, Yuriz Bakhtiar1, Aris Catur Bintoro3, Koji Iida4, Kaoru Kurisu4, Kazunori Arita2, Jacob Bunyamin1, Rofat Askoro1, Surya Pratama Brilliantika1, Novita Ikbar Khairunnisa1 & Zainal Muttaqin1 To share the experiences of organizing the epilepsy surgery program in Indonesia. This study was divided into two periods based on the presurgical evaluation method: the frst period (1999–2004), when interictal electroencephalogram (EEG) and magnetic resonance imaging (MRI) were used mainly for confrmation, and the second period (2005–2017), when long-term non-invasive and invasive video-EEG was involved in the evaluation. Long-term outcomes were recorded up to December 2019 based on the Engel scale. All 65 surgical recruits in the frst period possessed temporal lobe epilepsy (TLE), while 524 patients were treated in the second period. In the frst period, 76.8%, 16.1%, and 7.1% of patients with TLE achieved Classes I, II, and III, respectively, and in the second period, 89.4%, 5.5%, and 4.9% achieved Classes I, II, and III, respectively, alongside Class IV, at 0.3%. The overall median survival times for patients with focal impaired awareness seizures (FIAS), focal to bilateral tonic–clonic seizures and generalized tonic–clonic seizures were 9, 11 and 11 years (95% CI: 8.170– 9.830, 10.170–11.830, and 7.265–14.735), respectively, with p = 0.04. The utilization of stringent and selective criteria to reserve surgeries is important for a successful epilepsy program with limited resources.
    [Show full text]