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Adult Congenital Megacolon with Acute Fecal Obstruction and Diabetic Nephropathy: a Case Report
2726 EXPERIMENTAL AND THERAPEUTIC MEDICINE 18: 2726-2730, 2019 Adult congenital megacolon with acute fecal obstruction and diabetic nephropathy: A case report MINGYUAN ZHANG1,2 and KEFENG DING1 1Colorectal Surgery Department, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310000; 2Department of Gastrointestinal Surgery, Yinzhou Peoples' Hospital, Ningbo, Zhejiang 315000, P.R. China Received November 27, 2018; Accepted June 20, 2019 DOI: 10.3892/etm.2019.7852 Abstract. Megacolon is a congenital disorder. Adult congen- sufficient amount of bowel should be removed, particularly the ital megacolon (ACM), also known as adult Hirschsprung's aganglionic segment (2). The present study reports on a case of disease, is rare and frequently manifests as constipation. ACM a 56-year-old patient with ACM, fecal impaction and diabetic is caused by the absence of ganglion cells in the submucosa nephropathy. or myenteric plexus of the bowel. Most patients undergo treat- ment of megacolon at a young age, but certain patients cannot Case report be treated until they develop bowel obstruction in adulthood. Bowel obstruction in adults always occurs in complex clinical A 56-year-old male patient with a history of chronic constipa- situations and it is frequently combined with comorbidities, tion presented to the emergency department of Yinzhou including bowel tumors, volvulus, hernias, hypertension or Peoples' Hospital (Ningbo, China) in February 2018. The diabetes mellitus. Surgical intervention is always required in patient had experienced vague abdominal distention for such cases. To avoid recurrence, a sufficient amount of bowel several days. Prior to admission, chronic bowel obstruction should be removed, particularly the aganglionic segment. -
The American Society of Colon and Rectal Surgeons' Clinical Practice
CLINICAL PRACTICE GUIDELINES The American Society of Colon and Rectal Surgeons’ Clinical Practice Guideline for the Evaluation and Management of Constipation Ian M. Paquette, M.D. • Madhulika Varma, M.D. • Charles Ternent, M.D. Genevieve Melton-Meaux, M.D. • Janice F. Rafferty, M.D. • Daniel Feingold, M.D. Scott R. Steele, M.D. he American Society of Colon and Rectal Surgeons for functional constipation include at least 2 of the fol- is dedicated to assuring high-quality patient care lowing symptoms during ≥25% of defecations: straining, Tby advancing the science, prevention, and manage- lumpy or hard stools, sensation of incomplete evacuation, ment of disorders and diseases of the colon, rectum, and sensation of anorectal obstruction or blockage, relying on anus. The Clinical Practice Guidelines Committee is com- manual maneuvers to promote defecation, and having less posed of Society members who are chosen because they than 3 unassisted bowel movements per week.7,8 These cri- XXX have demonstrated expertise in the specialty of colon and teria include constipation related to the 3 common sub- rectal surgery. This committee was created to lead inter- types: colonic inertia or slow transit constipation, normal national efforts in defining quality care for conditions re- transit constipation, and pelvic floor or defecation dys- lated to the colon, rectum, and anus. This is accompanied function. However, in reality, many patients demonstrate by developing Clinical Practice Guidelines based on the symptoms attributable to more than 1 constipation sub- best available evidence. These guidelines are inclusive and type and to constipation-predominant IBS, as well. The not prescriptive. -
Delayed Presentation of a Retained Fecalith
Open Access Case Report DOI: 10.7759/cureus.15919 Delayed Presentation of a Retained Fecalith Fawwad A. Ansari 1 , Muhammad Ibraiz Bilal 1 , Muhammad Umer Riaz Gondal 1 , Mehwish Latif 2 , Nadeem Iqbal 2 1. Medicine, Shifa International Hospital, Islamabad, PAK 2. Gastroenterology, Shifa International Hospital, Islamabad, PAK Corresponding author: Fawwad A. Ansari, [email protected] Abstract A fecalith is a common cause of acute appendicitis, and laparoscopic surgery is the mainstay of its management. Literature review shows that a fecalith may be retained in the gut following a laparoscopic appendectomy in some rare cases. In most cases, the fecalith becomes symptomatic with time due to the formation of an abscess, fistulous tract, or inflammation of the appendicular stump (stump appendicitis). We report a case of retained appendicular fecalith presenting with symptoms similar to acute appendicitis, 15 years after laparoscopic appendectomy. Categories: Gastroenterology, General Surgery Keywords: colonoscopy, acute appendicitis, appendectomy, fecalith, right iliac fossa pain, complications Introduction A fecalith is a hard stony mass of feces in the intestinal tract. Fecal impaction occurs when a large amount of fecal matter gets compacted and cannot get evacuated spontaneously [1]. In its extreme form, fecal impaction can lead to the formation of a fecalith due to the hardening of fecal material that forms a mass separate from other bowel contents [2]. It can occur in any part of the intestine [1]. Most often, a fecalith arises in the colon (mostly sigmoid) or rectum and very rarely in the small intestine [2]. Here we present a case of a retained appendicular fecalith in a patient who presented with an acute abdomen. -
Gastroenterology and the Elderly
3 Gastroenterology and the Elderly Thomas W. Sheehy 3.1. Esophagus 3.1.1. Dysphagia Esophageal disorders, such as esophageal motility disorders, infections, tumors, and other diseases, are common in the elderly. In the elderly, dysphagia usually implies organic disease. There are two types: (1) pre-esophageal and (2) esophageal. Both are further subdivided into motor (neuromuscular) or structural (intrinsic and extrinsic) lesions.! 3.1.2. Pre-esophageal Dysphagia Pre-esophageal dysphagia (PED) usually implies neuromuscular disease and may be caused by pseudobular palsy, multiple sclerosis, amy trophic lateral scle rosis, Parkinson's disease, bulbar poliomyelitis, lesions of the glossopharyngeal nerve, myasthenia gravis, and muscular dystrophies. Since PED is due to inability to initiate the swallowing mechanism, food cannot escape from the oropharynx into the esophagus. Such patients usually have more difficulty swallowing liquid THOMAS W. SHEEHY • The University of Alabama in Birmingham, School of Medicine, Department of Medicine; and Medical Services, Veterans Administration Medical Center, Birming ham, Alabama 35233. 87 S. R. Gambert (ed.), Contemporary Geriatric Medicine © Plenum Publishing Corporation 1983 88 THOMAS W. SHEEHY than solids. They sputter or cough during attempts to swallow and often have nasal regurgitation or aspiration of food. 3.1.3. Dysfunction of the Cricopharyngeus Muscle In the elderly, this is one of the more common forms of PED.2 These patients have the sensation of an obstruction in their throat when they attempt to swallow. This is due to incoordination of the cricopharyngeus muscle. When this muscle fails to relax quickly enough during swallowing, food cannot pass freely into the esophagus. If the muscle relaxes promptly but closes too quickly, food is trapped as it attempts to enter the esophagus. -
Case Studies of Two Cystic Fibrosis Patients with Distal Intestinal Obstruction Syndrome (DIOS) and a Literature Review
Case report Case Studies of Two Cystic Fibrosis Patients with distal intestinal obstruction syndrome (DIOS) and a Literature review Johanna Pacheco A., MD,1 Olga Morales M., MD,2 Alejandra Wilches L., MD.3 1 Pediatrician from the University of Antioquia, Abstract Master’s Degree Student in Pediatric Clinical Nutrition at INTA in Chile Patients with cystic fibrosis (CF) have greater than normal mucosal viscosity and prolonged intestinal transit 2 Pediatric Pulmonologist in the Faculty of Medicine at times which can result in meconium ileus, distal intestinal obstruction syndrome (DIOS) and constipation of the University of Antioquia in Medellin, Colombia varying severity. 3 Pediatric Gastroenterologist at San Vicente Fundación Hospital Universitario in Medellín, The cystic fibrosis working group of the European Society of Gastroenterology, Hepatology and Pediatric Colombia Nutrition produced a consensus in 2010 that defined distal intestinal obstruction syndrome (DIOS) as acute intestinal obstruction which may be complete or incomplete. Fully developed DIOS is defined as bilious vo- The cases reported here were treated at San Vicente Fundación Hospital Universitario in Medellín, miting and/or sufficient amounts of fluid and air in the small intestine to be observed in an abdominal X-ray, a Colombia. fecal mass in the ileocecal area, pain and/or bloating. Incomplete DIOS is defined as abdominal pain and/or No financial resources or other resources from any bloating and fecal mass in the ileocecal area, but without the other signs of complete obstruction. Colombian or international entity were received for this research. The incidence of this condition in cystic fibrosis patients varies. Depending on the definition used, the preva- lence of DIOS has been measured between 7% and 8% in children with cystic fibrosis, but has been reported ........................................ -
Constipation.Pdf
Constipation National Digestive Diseases Information Clearinghouse What is constipation? The large intestine absorbs water and any remaining nutrients from partially digested Constipation is a condition in which a person food passed from the small intestine. The has fewer than three bowel movements a large intestine then changes waste from week or has bowel movements with stools liquid to a solid matter called stool. Stool that are hard, dry, and small, making them passes from the colon to the rectum. The painful or difficult to pass. People may feel rectum is located between the last part of bloated or have pain in their abdomen—the the colon—called the sigmoid colon—and area between the chest and hips. Some the anus. The rectum stores stool prior people think they are constipated if they do to a bowel movement. During a bowel not have a bowel movement every day. Bowel movement, stool moves from the rectum to movements may occur three times a day or the anus, the opening through which stool three times a week, depending on the person. leaves the body. Most people get constipated at some point in their lives. Constipation can be acute, which means sudden and lasting a short time, or chronic, which means lasting a long time, even years. Most constipation is acute and not dangerous. Understanding the causes, prevention, and treatment of constipation can help many people take steps to find relief. What is the gastrointestinal (GI) tract? Colon The GI tract is a series of hollow organs joined in a long, twisting tube from the mouth to the anus. -
Exponential Increase in Stool Crosslinking Is Mirrored in Systemic Inflammation and Associated to Fecal Acetate and Methionine
H OH metabolites OH Article The Importance of Objective Stool Classification in Fecal 1H-NMR Metabolomics: Exponential Increase in Stool Crosslinking Is Mirrored in Systemic Inflammation and Associated to Fecal Acetate and Methionine Leon Deutsch 1 and Blaz Stres 1,2,3,4,* 1 Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, SI-1000 Ljubljana, Slovenia; [email protected] 2 Faculty of Civil and Geodetic Engineering, University of Ljubljana, Jamova 2, SI-1000 Ljubljana, Slovenia 3 Department of Automation, Jožef Stefan Institute, Biocybernetics and Robotics, Jamova 39, SI-1000 Ljubljana, Slovenia 4 Department of Microbiology, University of Innsbruck, Technikerstrasse 25d, A-6020 Innsbruck, Austria * Correspondence: [email protected]; Tel.: +386-41-567-633 Abstract: Past studies strongly connected stool consistency—as measured by Bristol Stool Scale (BSS)—with microbial gene richness and intestinal inflammation, colonic transit time and metabolome characteristics that are of clinical relevance in numerous gastro intestinal conditions. While retention time, defecation rate, BSS but not water activity have been shown to account for BSS-associated Citation: Deutsch, L.; Stres, B. The inflammatory effects, the potential correlation with the strength of a gel in the context of intestinal Importance of Objective Stool forces, abrasion, mucus imprinting, fecal pore clogging remains unexplored as a shaping factor for Classification in Fecal 1H-NMR intestinal inflammation and has yet to be determined. Our study introduced a minimal pressure ap- Metabolomics: Exponential Increase proach (MP) by probe indentation as measure of stool material crosslinking in fecal samples. Results in Stool Crosslinking Is Mirrored in reported here were obtained from 170 samples collected in two independent projects, including males Systemic Inflammation and and females, covering a wide span of moisture contents and BSS. -
Report of an Unusual Case with Severe Fecal Impaction Responding to Medication Therapy
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by PubMed Central J Neurogastroenterol Motil, Vol. 16 No. 2 April, 2010 DOI: 10.5056/jnm.2010.16.2.199 Case Report JNM Journal of Neurogastroenterology and Motility Report of an Unusual Case With Severe Fecal Impaction Responding to Medication Therapy Wei Zhao, MD and Meiyun Ke, MD* Department of Gastroenterology, PUMC Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China ㅋ Fecal impaction is a disorder characterized by a large mass of compacted feces in the rectum and/or colon, which cannot be evacuated. For mild and moderate fecal impaction, recommended treatments include stool softeners, oral mineral and olive oil, and edema; for severe fecal impaction, manual removal is needed and sometimes laparotomy may be indicated if medical therapies are not effective. Here we report a case with severe fecal impaction who did not defecate for 75 days. We treated this patient with vegetable oil, Chinese traditional medicine and enema in sequence. After 12 days of therapy, she evacuated hard fecal masses, and the symptoms were relieved. (J Neurogastroenterol Motil 2010;16:199-202) Key Words Fecal impaction, Intestinal obstruction, Therapy severe fecal impaction with no bowel movements for 75 days, in whom vegetable oil, Chinese traditional medicine and enema ad- Introduction ministered in sequence successively relieved the symptoms. Fecal impaction is a disorder characterized by a large mass of compacted feces in the rectum and/or colon, which cannot be evacuated. It is reported fecal impaction can occur in childhood, Case Report old age and some patients with spinal cord injury.1 With less sys- A 55-year-old Chinese woman visited gastrointestinal clinic temic review, the true incidence is not certain. -
A Deep Learning Approach to Human Stool Recognition And
Augmenting Gastrointestinal Health: A Deep Learning Approach to Human Stool Recognition and Characterization in Macroscopic Images David Hachuel Akshay Jha Deborah Estrin, PhD Cornell Tech Cornell Tech Cornell Tech Cornell University Cornell University Cornell University New York, NY, USA New York, NY, USA New York, NY, USA [email protected] [email protected] [email protected] Alfonso Martinez Kyle Staller, MD, MPH Christopher Velez, MD Massachusetts Institute Massachusetts General Massachusetts General of Technology Hospital Hospital Cambridge, MA, USA Boston, MA, USA Boston, MA, USA [email protected] [email protected] [email protected] ABSTRACT Results - In terms of inter-rater reliability, the Kappa score UPDATED—4 December 2018. Purpose - Functional was κ = 0.5840. Regarding the stool detection task, our bowel diseases, including irritable bowel syndrome, chronic modified SegNet produced a 71.93% mIoU on a test set of constipation, and chronic diarrhea, are some of the most 282 images when trained on 651 images. Current common diseases seen in clinical practice. Many patients state-of-the-art segmentation models reach 83.2% mIoU describe a range of triggers for altered bowel consistency when trained on significantly larger datasets. As for BSS and symptoms. However, characterization of the classification using the ResNet architecture, our mean relationship between symptom triggers using bowel diaries accuracy is 74.26% on a test set of 272 images when trained is hampered by poor compliance and lack of objective stool on 614 images. In comparison, the ResNet trained on the consistency measurements. We sought to develop a stool secondary dataset achieved 99.4% accuracy in classifying detection and tracking system using computer vision and BSS on a test set of 10800 images when trained on 25200 deep convolutional neural networks (CNN) that could be images. -
And Sulphate-Rich Natural Mineral Water in Functional Constipation
Nutrition 65 (2019) 167À172 Contents lists available at ScienceDirect Nutrition journal homepage: www.nutritionjrnl.com Applied nutritional investigation Time to treatment response of a magnesium- and sulphate-rich natural mineral water in functional constipation Christophe Dupont M.D., Ph.D. a,*, Florence Constant M.D., Ph.D. b, Aurelie Imbert M.Sc. b, Guillaume Hebert Ph.D., M.B.A. c, Othar Zourabichvili M.D., Ph.D. d, Nathalie Kapel Pharm.D., Ph.D. e a Service d'Explorations Fonctionnelles Digestives Pediatriques, AP-HP, Hopital^ Necker Enfant Malade, Universite Paris Descartes, Paris, France b Nestle Waters M.T., Issy-les-Moulineaux, France c SC Partners, Paris, France d Quanta Medical, Rueil-Malmaison, France e Laboratoire de Coprologie Fonctionnelle, Hopitaux^ Universitaires Pitie Salp^etriere - Charles Foix, APHP, Paris, France ARTICLE INFO ABSTRACT Article History: Objectives: First-line recommendations for the management of functional constipation include nutritional- Received 11 June 2018 hygienic measures. We previously showed that a natural mineral water rich in sulphates and magnesium Received in revised form 22 February 2019 (Hepar) is efficient in the treatment of functional constipation. The aim of this study was to consolidate those Accepted 24 February 2019 first results and determine a precise time to respond to Hepar. Keywords: Methods: This multicenter, randomized, double-blind, controlled study of the effect of Hepar on stool consis- Bowel movement tency and frequency in functional constipation included 226 outpatients. After washout, patients used 1.5 L Functional constipation of water daily, including 1 L of Hepar or of low-mineral water, during 14 d. In addition to a daily reporting of Clinical trial stool consistency by the patient, an expert investigator blindly analyzed stool consistency (Bristol stool scale) Natural mineral water based on photographs taken by the patient. -
Tracy Aldridge, MD Constipation Bowel Obstruction
11/18/2013 Tracy Aldridge, MD Constipation ◦ Occasional- episode of constipation which resolves easily from time to time. Everyone has occasional constipation. ◦ Chronic- requiring treatment with medications to control symptoms and maintain regular bowel movements. Bowel Obstruction ◦ Small Bowel Obstruction ◦ Large Bowel Obstruction 1 11/18/2013 Small intestine ◦ (also called the small bowel) Large intestine ◦ (also called the large bowel, or colon) Constipation is defined as having a bowel movement fewer than three times per week. Stools are usually hard, dry, small in size, and difficult to eliminate. Normal bowel function can range from three times a day or three times a week, depending on the person. 2 11/18/2013 Developmental disabilities ◦ Less active, poor dietary fiber, less fluid intake Neuromuscular disorders ◦ Abnormal nerve and muscle response or coordination in the bowel Cerebral palsy ◦ Poor nerve responses within the bowel causing motility problems Medication side effects ◦ Slowing of the transit time or alteration of bowel consistency or fluid content Spending a lot of time on the toilet Stra ining a nd g ru nt ing while pass ing stoo l Hard, small, dry feces Bloating and complaints of stomach discomfort Engages in rectal digging 3 11/18/2013 Conservative and/or preventive measures ◦ Increase fluid intake if able ◦ Increase fiber intake ◦ Increase physical activity Laxative medications ◦ Stimulants (such as senna, docusate) These help stimulate the intestine to move food and fluid through. ◦ Stool softeners (colace) Increase the liquid content of the stool to make it easier to pass ◦ Lubricant laxatives (mineral oil) ◦ Osmot ic agents (suc h as Milk of M agnesi a, Mira lax) These act like a sponge, drawing fluid into the bowel to help with elimination. -
7/10/2015 1 Constipation (Bowel Disorders) Aspiration
7/10/2015 Dr. Tracy Aldridge, MD Medical Director, DHS DD Assistant Professor, Family and Community Medicine SIU School of Medicine Constipation (Bowel Disorders) Aspiration (Dysphagia) Dehydration Seizure Disorder 1 7/10/2015 Constipation ◦ Occasional- episode of constipation which resolves easily from time to time. Everyone has occasional constipation. ◦ Chronic- requiring treatment with medications to control symptoms and maintain regular bowel movements. Bowel Obstruction ◦ Small Bowel Obstruction ◦ Large Bowel Obstruction 2 7/10/2015 Small intestine ◦ (also called the small bowel) Large intestine ◦ (also called the large bowel, or colon) Constipation is defined as having a bowel movement fewer than three times per week. Stools are usually hard, dry, small in size, and difficult to eliminate. Normal bowel function can range from three times a day or three times a week, depending on the person. 3 7/10/2015 Developmental disabilities ◦ Less active, poor dietary fiber, less fluid intake Neuromuscular disorders ◦ Abnormal nerve and muscle response or coordination in the bowel Cerebral palsy ◦ Poor nerve responses within the bowel causing motility problems Medication side effects ◦ Slowing of the transit time or alteration of bowel consistency or fluid content Spending a lot of time on the toilet Straining and grunting while passing stool Hard, small, dry feces Bloating and complaints of stomach discomfort Engages in rectal digging 4 7/10/2015 Conservative and/or preventive measures ◦ Increase fluid intake if able ◦ Increase fiber intake ◦ Increase physical activity Laxative medications ◦ Stimulants (such as senna, docusate) These help stimulate the intestine to move food and fluid through. ◦ Stool softeners (colace) Increase the liquid content of the stool to make it easier to pass ◦ Lubricant laxatives (mineral oil) ◦ Osmotic agents (such as Milk of Magnesia, Miralax) These act like a sponge, drawing fluid into the bowel to help with elimination.