Establishment of Wmel Wolbachia in Aedes Aegypti Mosquitoes and Reduction of Local Dengue Transmission in Cairns
Gates Open Research Gates Open Research 2019, 3:1547 Last updated: 18 OCT 2019 RESEARCH ARTICLE Establishment of wMel Wolbachia in Aedes aegypti mosquitoes and reduction of local dengue transmission in Cairns and surrounding locations in northern Queensland, Australia [version 1; peer review: 2 approved] Peter A. Ryan 1, Andrew P. Turley1, Geoff Wilson1, Tim P. Hurst1,2, Kate Retzki1, Jack Brown-Kenyon1, Lauren Hodgson1, Nichola Kenny1, Helen Cook1, Brian L. Montgomery1,3, Christopher J. Paton4, Scott A. Ritchie1,4, Ary A. Hoffmann5, Nicholas P. Jewell6,7, Stephanie K. Tanamas1, Katherine L. Anders 1, Cameron P. Simmons1,8, Scott L. O’Neill 1 1Institute of Vector-Borne Disease, Monash University, Clayton, Victoria, 3800, Australia 2Biosecurity and Agricultural Services, Department of Jobs, Precincts and Regions, Victoria State Government, Atwood, Victoria, Australia 3Metro South Public Health Unit, Queensland Health, Coopers Plains, Queensland, Australia 4College of Public Health, Medical and Veterinary Sciences, James Cook University, Cairns, Queensland, Australia 5School of Biosciences, Bio21 Institute, University of Melbourne, Parkville, Victoria, Australia 6Division of Epidemiology and Biostatistics, School of Public Health, University of California, Berkeley, California, USA 7Centre for Statistical Methodology, London School of Hygiene and Tropical Medicine, London, UK 8Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam First published: 26 Sep 2019, 3:1547 ( Open Peer Review v1 https://doi.org/10.12688/gatesopenres.13061.1) Latest published: 26 Sep 2019, 3:1547 ( https://doi.org/10.12688/gatesopenres.13061.1) Reviewer Status Abstract Invited Reviewers Background: The wMel strain of Wolbachia has been successfully 1 2 introduced into Aedes aegypti mosquitoes and subsequently shown in laboratory studies to reduce transmission of a range of viruses including version 1 dengue, Zika, chikungunya, yellow fever, and Mayaro viruses that cause published report report human disease.
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