Manual 13 Health Aspects of Chemical, Biological and Radiological Hazards
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Job Hazard Analysis
Identifying and Evaluating Hazards in Research Laboratories Guidelines developed by the Hazards Identification and Evaluation Task Force of the American Chemical Society’s Committee on Chemical Safety Copyright 2013 American Chemical Society Table of Contents FOREWORD ................................................................................................................................................... 3 ACKNOWLEDGEMENTS ................................................................................................................................. 5 Task Force Members ..................................................................................................................................... 6 1. SCOPE AND APPLICATION ..................................................................................................................... 7 2. DEFINITIONS .......................................................................................................................................... 7 3. HAZARDS IDENTIFICATION AND EVALUATION ................................................................................... 10 4. ESTABLISHING ROLES AND RESPONSIBILITIES .................................................................................... 14 5. CHOOSING AND USING A TECHNIQUE FROM THIS GUIDE ................................................................. 17 6. CHANGE CONTROL .............................................................................................................................. 19 7. ASSESSING -
Proceedings of the International Cyanide Detection Testing Workshop
Proceedings of the International Cyanide Detection Testing Workshop February 6-8, 2008 Orlando, Florida Edited by Andrew W. Bruckner Glynnis G. Roberts U.S. Department of Commerce National Oceanic and Atmospheric Administration National Marine Fisheries Service NOAA Technical Memorandum NMFS-OPR-40 August 2008 This publication should be cited as: Bruckner, A.W. and G. Roberts (editors). 2008. Proceedings of the International Cyanide Detection Testing Workshop. NOAA Technical Memorandum NMFS-OPR-40, Silver Spring, MD 164 pp. Signifi cant support for the development of this document was provided by NOAA Fisheries, Offi ce of Habitat Conservation, and NOAA’s Coral Reef Conservation Program. The views expressed in this document are those of the authors and the participants of the workshop, and do not necessarily refl ect the offi cial views or policies of the U.S. Government, NOAA or DOS. Front Cover Images: (Top) James Cervino – A fi sher uses cyanide to catch marine ornamental fi sh; (Bottom) Stephen Why – Pens used in Micronesia to hold live reef food fi sh. Additional copies of this publication may be requested from: John Foulks National Oceanic and Atmospheric Administration NOAA National Marine Fisheries Service Offi ce of Habitat Conservation 1315 East West Highway Silver Spring, MD 20910 [email protected] Proceedings of the Cyanide Detection Testing Workshop Edited by Andrew W. Bruckner and Glynnis G. Roberts Offi ce of Habitat Conservation Ecosystem Assessment Division NOAA National Marine Fisheries Service 1315 East-West Highway Silver Spring, MD 20910-3282 NOAA Technical Memorandum NMFS-OPR-40 August 2008 U.S. Department of Commerce Carlos Gutierrez, Secretary National Oceanic and Atmospheric Administration Vice Admiral Conrad C. -
Cyanobacterial Toxins: Saxitoxins
WHO/SDE/WSH/xxxxx English only Cyanobacterial toxins: Saxitoxins Background document for development of WHO Guidelines for Drinking-water Quality and Guidelines for Safe Recreational Water Environments Version for Public Review Nov 2019 © World Health Organization 20XX Preface Information on cyanobacterial toxins, including saxitoxins, is comprehensively reviewed in a recent volume to be published by the World Health Organization, “Toxic Cyanobacteria in Water” (TCiW; Chorus & Welker, in press). This covers chemical properties of the toxins and information on the cyanobacteria producing them as well as guidance on assessing the risks of their occurrence, monitoring and management. In contrast, this background document focuses on reviewing the toxicological information available for guideline value derivation and the considerations for deriving the guideline values for saxitoxin in water. Sections 1-3 and 8 are largely summaries of respective chapters in TCiW and references to original studies can be found therein. To be written by WHO Secretariat Acknowledgements To be written by WHO Secretariat 5 Abbreviations used in text ARfD Acute Reference Dose bw body weight C Volume of drinking water assumed to be consumed daily by an adult GTX Gonyautoxin i.p. intraperitoneal i.v. intravenous LOAEL Lowest Observed Adverse Effect Level neoSTX Neosaxitoxin NOAEL No Observed Adverse Effect Level P Proportion of exposure assumed to be due to drinking water PSP Paralytic Shellfish Poisoning PST paralytic shellfish toxin STX saxitoxin STXOL saxitoxinol -
Cem-Seal-SDS Sheet
Cem-Seal ICP Building Solutions Group/Pli-Dek Version No: 1.2 Issue Date: 10/26/2020 Safety Data Sheet according to OSHA HazCom Standard (2012) requirements Print Date: 10/26/2020 S.GHS.USA.EN SECTION 1 Identification Product Identifier Product name Cem-Seal Synonyms Not Available Other means of identification Not Available Recommended use of the chemical and restrictions on use Relevant identified uses Specialty floor coating Name, address, and telephone number of the chemical manufacturer, importer, or other responsible party Registered company name ICP Building Solutions Group/Pli-Dek Address 4565 W. Watkins Street Phoenix AZ Not applicable Telephone 623-435-2277 Fax Not Available Website www.ICPGROUP.com Email Not Available Emergency phone number Association / Organisation ChemTel Emergency telephone 1-800-255-3924 numbers Other emergency telephone 1-813-248-0585 numbers SECTION 2 Hazard(s) identification Classification of the substance or mixture NFPA 704 diamond Note: The hazard category numbers found in GHS classification in section 2 of this SDSs are NOT to be used to fill in the NFPA 704 diamond. Blue = Health Red = Fire Yellow = Reactivity White = Special (Oxidizer or water reactive substances) Classification Acute Aquatic Hazard Category 3 Label elements Hazard pictogram(s) Not Applicable Signal word Not Applicable Hazard statement(s) H402 Harmful to aquatic life. Hazard(s) not otherwise classified Not Applicable Precautionary statement(s) General P101 If medical advice is needed, have product container or label at hand. P102 Keep out of reach of children. Page 1 continued... Version No: 1.2 Page 2 of 8 Issue Date: 10/26/2020 Cem-Seal Print Date: 10/26/2020 Precautionary statement(s) Prevention P273 Avoid release to the environment. -
War Gases .Pdf
yh&% .*i From the collection of the m Prejinger h v Jjibrary San Francisco, California 2007 THE WAR GASES WAR GASES Their Identification and Decontamination BY MORRIS B. JACOBS, Ph.D. Food, Drug and Insecticide Admin. U. S. Dept. of Agr. 1927 Chemist Department of Health, City of New York, 1928. Formerly, Lt. U. S. Chemical Warfare Service Reserve INTERSCIENCE PUBLISHERS, INC. NEW YORK, N. Y.-1942 Copyright, 1942, by INTERSCIENCE PUBLISHERS, INC. 215 Fourth Avenue, New York, N. Y. Printed in U. S. A. by WAVERLY PRESS, BALTIMORE, MD. PREFACE Relatively little has been written in the United States of America on the subject of passive defense, or as we would put it, civilian defense against poison gas. One of the very first steps in defense of this nature is a system for the detection, the sampling and the identification of the chemical war- fare agents, and the decontamination of areas and materials polluted by them. It is the aim of this book to present these subjects so that the informa- tion given will be useful to the gas identification officer, the war gas chemist, the decontamination officer, and the health officer. While this book was written primarily for the aforementioned officers, Chapters I, II, III, part of IV and VII should prove of value to the air raid warden and, in general, to all persons dealing with the above mentioned phases of gas defense. It is written so that it can be used for the training of gas identifi- cation officers, as a manual by chemists and decontamination officers, and as a source of information on the analytical chemistry of the war gases. -
Controlling Chemical Exposure Industrial Hygiene Fact Sheets
Controlling Chemical Exposure Industrial Hygiene Fact Sheets Concise guidance on 16 components of industrial hygiene controls New Jersey Department of Health and Senior Services Division of Epidemiology, Environmental and Occupational Health Occupational Health Service PO Box 360 Trenton, NJ 08625-0360 609-984-1863 October 2000 James E. McGreevey Clifton R. Lacy, M.D. Governor Commissioner Written by: Eileen Senn, MS, CIH Occupational Health Surveillance Program James S. Blumenstock Senior Assistant Commissioner Public Health Protection and Prevention Programs Eddy Bresnitz, MD, MS State Epidemiologist/Assistant Commissioner Division of Epidemiology, Environmental and Occupational Health Kathleen O’Leary, MS Director Occupational Health Service David Valiante, MS, CIH Acting Program Manager Occupational Health Surveillance Program Funding: This project was supported in part by a cooperative agreement from the U.S. Department of Health and Human Services, National Institute for Occupational Safety and Health (NIOSH). Reproduction: The NJDHSS encourages the copying and distribution of all or parts of this booklet. All materials are in the public domain and may be reproduced or copied without permission. Cita- tion as to the source is appreciated. This document is available on the Internet at: www.state.nj.us/health/eoh/survweb/ihfs.pdf Citation: Senn, E., Controlling Chemical Exposure; Industrial Hygiene Fact Sheets, Trenton, NJ: New Jersey Department of Health and Senior Services, October 2000. Table of Contents Methods for Controlling -
Development and Validation of a Novel Approach for the Analysis of Marine Biotoxins
DEVELOPMENT AND VALIDATION OF A NOVEL APPROACH FOR THE ANALYSIS OF MARINE BIOTOXINS Bing Cheng Chai College of Engineering and Science Victoria University Submitted in fulfilment of the requirements of the degree of Doctor of Philosophy June 2017 ABSTRACT Harmful algal blooms (HABs) which can produce a variety of marine biotoxins are a prevalent and growing risk to public safety. The aim of this research was to investigate, evaluate, develop and validate an analytical method for the detection and quantitation of five important groups of marine biotoxins in shellfish tissue. These groups included paralytic shellfish toxins (PST), amnesic shellfish toxins (AST), diarrheic shellfish toxins (DST), azaspiracids (AZA) and neurotoxic shellfish toxins (NST). A novel tandem liquid chromatographic (LC) approach using hydrophilic interaction chromatography (HILIC), aqueous normal phase (ANP), reversed phase (RP) chromatography, tandem mass spectrometry (MSMS) and fluorescence spectroscopic detection (FLD) was designed and tested. During method development of the tandem LC setup, it was found that HILIC and ANP columns were unsuitable for the PSTs because of the lack of chromatographic separation power, precluding them from being used with MSMS detection. In addition, sensitivity for the PSTs at regulatory limits could not be achieved with MSMS detection, which led to a RP-FLD combination. The technique of RP-MSMS was found to be suitable for the remaining four groups of biotoxins. The final method was a combination of two RP columns coupled with FLD and MSMS detectors, with a valve switching program and injection program. A novel sample preparation method was also developed for the extraction and clean-up of biotoxins from mussels. -
SAXITOXIN ELISA a Competitive Enzyme Immunoassay For
SAXITOXIN ELISA (5191SAXI[5]04.20) A competitive enzyme immunoassay for screening and quantitative analysis of Saxitoxin in various matrices EUROPROXIMA SAXITOXIN ELISA A competitive enzyme immunoassay for screening and quantitative analysis of Saxitoxin in various matrices TABLE OF CONTENTS PAGE: Brief Information .............................................................. 2 1. Introduction ...................................................................... 2 2. Principle of Saxitoxin ELISA ............................................ 3 3. Specificity and Sensitivity ................................................ 4 4. Handling and Storage ...................................................... 5 5. Kit contents ...................................................................... 6 6. Equipment required but not provided .............................. 7 7. Precautions ...................................................................... 7 8. Sample preparation ......................................................... 8 9. Preparation of reagents ................................................... 8 10. Assay Procedure ............................................................. 10 11. Interpretation of results .................................................... 12 12. Literature .......................................................................... 13 13. Ordering information ........................................................ 13 14. Revision history ............................................................... -
Job Safety Analysis
Job Safety Analysis BWC Division of Safety and Hygiene Training Center Introduction Job Safety Analysis Table of Contents Tab Page Introduction Objectives 2 Agenda 3 BWC Office Locations 4 Introduction Slides 5 PowerPoint 9 Content JSA Educational Material 25 Job Hazard Control Plan 32 Job Safety Analysis Review Checklist 36 Sample Approved JSA 39 Typical Errors on JSA 40 Sample Job Hazard Analysis 41 Downloading Materials (one-hour presentation) from Web 42 Resources Additional Resources 43 JSA Planning Sheet 45 Hazard Identification Checklist 46 Questions to Ask When Determining Controls 48 National Safety Council JSA & Directions 49 PNW/APS Safety Performance 51 OSHA Job Safety Analysis 55 JSA Forms 81 February 2008 Printed within BWC Job Safety Analysis Objectives You will learn: - A proactive approach to incident prevention and safety; - The purpose and benefits of a JSA; - Techniques for performing a JSA; - How to conduct and document a JSA; - How to analyze the results of your JSA; - How to implement your safe job procedures; - How to manage and maintain your JSA process. 2 Job Safety Analysis Agenda 8:30 am - 11:30 am - Introductions - What do you want to take away from class? - Review material in book - How to do a JSA - Video and group discussion of video afterwards 11:30 am - 12:30 pm - Lunch 1:30 pm - 3:30 pm - JSA practical exercises - Group discussion of and explanation of results of exercises: corrective actions, identifying steps, and identifying hazards. 3:30 pm - 4:30 pm - Review session - Website demos - Q&A - Evaluations 3 BWC Columbus Logan 30 W. -
Chapter 9: Chemical Hazard Information
CHEMICAL HAZARD INFORMATION CHAPTER 9 CONTENTS Overview ............................................................................................... 121 Reactive nature of chemicals ............................................................... 121 Organization of the chemical hazard information table ......................... 124 CHEMICAL HAZARD INFORMATION | Overview Many chemicals have minimal hazards, making them relatively safe to use. Others pose inherent risks and require specific precautions. Still, other chemicals must be handled with such extreme care that they are not practical or safe for school usage. This chapter provides a link to information on hazards for nearly 600 chemicals to help teachers, schools and divisions select and safely use chemicals. Schools and jurisdictions may use this information as a starting point for reviewing chemicals currently on its shelves (particularly where chemicals have accumulated over the years), and reassessing the scope and contents of chemical inventories. The information in this chapter includes numeric ratings for health, flammability and reactivity, plus supplementary comments on the scope and severity of hazards. It also includes WHMIS and storage classifications, as well as transportation hazard classes and disposal methods.This information has been compiled from the most reliable and accurate sources available at the time of writing. Inclusion of a chemical in the link listing does not signal appropriateness for school use, but is provided as preliminary information on potential concerns. Given the nature and severity of hazards involved, some of the chemicals listed are designated as not appropriate for use in schools due to safety considerations. Readers are advised to consult MSDS sheets and other current sources of more detailed information before using any of the chemicals listed in the link. Omission from this list is also not an indication of safety. -
HAZARD COMMUNICATION COMPLIANCE CHECKLIST Item Y N
HAZARD COMMUNICATION COMPLIANCE CHECKLIST Item Y N 1. Population Identification A criterion is established to determine employees that need Hazard Communication (HAZCOM) training? [The ANew Employee/Guest Orientation” form may be one method of compliance] 2. Training for identified populations a. Workers have received HAZCOM Standard Training (IND 200) [Retraining every two years is recommended. The audit criteria will be a current understanding of the Hazard Communication program and chemical safety by the employee.] b. Workers have received training on hazards specific to their area [May include “on-the- job” training, DACUMS, JTA, JSA, discussions with supervisor, tool box training, etc.] c. Workers are informed of safety requirements when new hazards are introduced into the workplace. 3. Hazard Information a. A copy of MSDSs for all chemicals used by the worker is kept in the location OR the BNL on- line MSDS system is used (http://www.esh.bnl.gov/cms/). b. Workers can demonstrate how to obtain a Material Safety Data Sheet (MSDS). c. MSDSs for chemicals, NOT acquired through Supply & Material Receiving are forwarded to the Safety & Health Services Division MSDS program (Building 129). d. Workers can demonstrate the ability to comprehend hazard information from MSDSs. e. Workers have a clear understanding of the hazards of the chemical they use (based on training and review of the MSDS). 4. Hazard Recognition and Control a. The supervisor (or cognizant individual) conducts a review prior to the use of chemicals to determine the appropriate protective measures. b. Workers follow appropriate protective measures established by their supervisor. 1. Hoods, vents or other engineering controls are used as necessary. -
Patent Application Publication ( 10 ) Pub . No . : US 2019 / 0192440 A1
US 20190192440A1 (19 ) United States (12 ) Patent Application Publication ( 10) Pub . No. : US 2019 /0192440 A1 LI (43 ) Pub . Date : Jun . 27 , 2019 ( 54 ) ORAL DRUG DOSAGE FORM COMPRISING Publication Classification DRUG IN THE FORM OF NANOPARTICLES (51 ) Int . CI. A61K 9 / 20 (2006 .01 ) ( 71 ) Applicant: Triastek , Inc. , Nanjing ( CN ) A61K 9 /00 ( 2006 . 01) A61K 31/ 192 ( 2006 .01 ) (72 ) Inventor : Xiaoling LI , Dublin , CA (US ) A61K 9 / 24 ( 2006 .01 ) ( 52 ) U . S . CI. ( 21 ) Appl. No. : 16 /289 ,499 CPC . .. .. A61K 9 /2031 (2013 . 01 ) ; A61K 9 /0065 ( 22 ) Filed : Feb . 28 , 2019 (2013 .01 ) ; A61K 9 / 209 ( 2013 .01 ) ; A61K 9 /2027 ( 2013 .01 ) ; A61K 31/ 192 ( 2013. 01 ) ; Related U . S . Application Data A61K 9 /2072 ( 2013 .01 ) (63 ) Continuation of application No. 16 /028 ,305 , filed on Jul. 5 , 2018 , now Pat . No . 10 , 258 ,575 , which is a (57 ) ABSTRACT continuation of application No . 15 / 173 ,596 , filed on The present disclosure provides a stable solid pharmaceuti Jun . 3 , 2016 . cal dosage form for oral administration . The dosage form (60 ) Provisional application No . 62 /313 ,092 , filed on Mar. includes a substrate that forms at least one compartment and 24 , 2016 , provisional application No . 62 / 296 , 087 , a drug content loaded into the compartment. The dosage filed on Feb . 17 , 2016 , provisional application No . form is so designed that the active pharmaceutical ingredient 62 / 170, 645 , filed on Jun . 3 , 2015 . of the drug content is released in a controlled manner. Patent Application Publication Jun . 27 , 2019 Sheet 1 of 20 US 2019 /0192440 A1 FIG .