Coca Myths T N Drugs and Democracy Programme I
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LARC Resources on Indigenous Languages and Peoples of the Andes Film
LARC Resources on Indigenous Languages and Peoples of the Andes The LARC Lending Library has an extensive collection of educational materials for teacher and classroom use such as videos, slides, units, books, games, curriculum units, and maps. They are available for free short term loan to any instructor in the United States. These materials can be found on the online searchable catalog: http://stonecenter.tulane.edu/pages/detail/48/Lending-Library Film Apaga y Vamonos The Mapuche people of South America survived conquest by the Incas and the Spanish, as well as assimilation by the state of Chile. But will they survive the construction of the Ralco hydroelectric power station? When ENDESA, a multinational company with roots in Spain, began the project in 1997, Mapuche families living along the Biobio River were offered land, animals, tools, and relocation assistance in return for the voluntary exchange of their land. However, many refused to leave; some alleged that they had been marooned in the Andean hinterlands with unsafe housing and, ironically, no electricity. Those who remained claim they have been sold out for progress; that Chile's Indigenous Law has been flouted by then-president Eduardo Frei, that Mapuches protesting the Ralco station have been rounded up and prosecuted for arson and conspiracy under Chile's anti-terrorist legislation, and that many have been forced into hiding to avoid unfair trials with dozens of anonymous informants testifying against them. Newspaper editor Pedro Cayuqueo says he was arrested and interrogated for participating in this documentary. Directed by Manel Mayol. 2006. Spanish w/ English subtitles, 80 min. -
Legalization of the Non-Medical Use of Drugs Is Presented Below
I. OVERVIEW 1. Measures taken nationally and internationally to reduce drug abuse and trafficking have yet to yield more universally visible and decisive results and, consequently, the validity and appropriateness of the drug control measures that Governments have agreed upon in international conventions and resolutions have continued to be questioned. The drug abuse and trafficking situation, which is accompanied by violence and corruption, remains grim, but the International Narcotics Control Board is not convinced that valid alternatives to present policies have been found that would meaningfully reverse the situation. Worldwide efforts to combat drug abuse and trafficking have to be continuous, balanced and in an internationally concerted manner in order for further positive results to be achieved. Drug abuse is closely linked to political, social and economic problems, and progress in these areas will undeniably contribute to the solution of the drug abuse problem. In a number of countries positive developments have been reported and these should be more carefully studied and discussed so that successful experiences in one country can be considered by others. In addition, the mass media are invited to analyse and report on such positive developments. 2. The efforts of the United Nations International Drug Control Programme (UNDCP) are highly appreciated by the Board. During 1992, UNDCP cooperated with 97 countries through 130 regional and country-specific drug control programmes. In addition, the operational work programme for 1992 included 30 global projects supporting a broad range of drug control activities, such as specialized training, research and advisory services. These activities have been implemented by UNDCP in collaboration with various specialized agencies of the United Nations system, other international organizations and various non-governmental organizations. -
Interactions Between Ethanol and Cocaine, Amphetamine, Or MDMA in the Rat: Thermoregulatory and Locomotor Effects
Psychopharmacology DOI 10.1007/s00213-007-1007-5 ORIGINAL INVESTIGATION Interactions between ethanol and cocaine, amphetamine, or MDMA in the rat: thermoregulatory and locomotor effects Sami Ben Hamida & Erin Plute & Brigitte Cosquer & Christian Kelche & Byron C. Jones & Jean-Christophe Cassel Received: 22 May 2007 /Accepted: 29 October 2007 # Springer-Verlag 2007 Abstract duced by EtOH alone. Conversely, EtOH attenuated Rationale (±)-3,4-methylenedioxymethamphetamine MDMA-related hyperthermia, an effect increasing across (MDMA, ecstasy) is often taken recreationally with ethanol treatment days. These results demonstrate that the interac- (EtOH). In rats, EtOH may potentiate MDMA-induced tion between MDMA and EtOH may be different from the hyperactivity, but attenuate hyperthermia. interaction between EtOH and AMPH or COCA. Objective Experiment 1 compared the interactions between Conclusion Because of potential health-related consequen- EtOH (1.5 g/kg) and MDMA (6.6 mg/kg) with EtOH + ces of such polydrug misuse, it is worth identifying the cocaine (COCA; 10 mg/kg) and EtOH + amphetamine mechanisms underlying these interactions, especially be- (AMPH; 1 mg/kg) on locomotor activity and thermoregu- tween EtOH and MDMA. Given the different affinity lation. Experiment 2 used a weaker dose of MDMA profiles of the three drugs for serotonin, dopamine, and (3.3 mg/kg) and larger doses of COCA (20 mg/kg) and norepinephrine transporters, our results appear compatible AMPH (2 mg/kg). with the possibility of an important role of serotonin in at Materials and methods Drug treatments were administered least the EtOH-induced potentiation of MDMA-induced on four occasions (2, 5, and 2 days apart, respectively; hyperlocomotion. -
A User's Guide to Methamphetamine
A USER’S GUIDE TO METHAMPHETAMINE A self-help guide to reduce harm for people who use methamphetamine 1st Edition, March 2017 Acknowledgements This booklet was adapted from an original publication created by The National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia. This information does not constitute medical advice. Please seek the immediate help of a qualified medical practitioner about any personal health concerns. This booklet is being distributed for information purposes only. In the current state of crisis related to crystal methamphetamine, this booklet is intended as a guide to reduce harm for people who use methamphetamine. It lists the most common features of methamphetamine use, ways to reduce harm associated with the use of meth, and strategies for cutting down and quitting. The best way to avoid problems with drugs is to not use them. We are grateful for the contributions of the Integrated Drug Strategies in Waterloo Region and Guelph Wellington, in particular the leadership of Adrienne Crowder and Lindsay Sprague. Don Roth, Kerry Manthenga, Shirley Hilton, and our community review team provided great support and helpful edits. Marcey Gray provided exemplary skill on the design, images and editing, with final expert assistance from Arkay Design and Print. We are thankful for the financial support to print copies from the Waterloo-Wellington Human Services and Justice Coordinating Committee. For more information please contact: Wellington Guelph Drug Strategy www.wgdrugstrategy.ca Waterloo Region Integrated Drugs Strategy www.waterlooregiondrugstrategy.ca Circulated with the support of: WaterlooRegion Integrated Drugs Strategy WaterlooRegion Integrated Drugs Strategy The best way to avoid problems with drugs is to not use them. -
Booklet 4 Stimulants Preface
4 STIMULANTS 4 STIMULANTS 2019 2019 © United Nations, June 2019. All rights reserved worldwide. ISBN: 978-92-1-148314-7 eISBN: 978-92-1-004174-4 United Nations publication, Sales No. E.19.XI.8 This publication may be reproduced in whole or in part and in any form for educational or non-profit purposes without special permission from the copyright holder, provided acknowledgement of the source is made. The United Nations Office on Drugs and Crime (UNODC) would appreciate receiving a copy of any publication that uses this publication as a source. Suggested citation: World Drug Report 2019 (United Nations publication, Sales No. E.19.XI.8). No use of this publication may be made for resale or any other commercial purpose whatsoever without prior permission in writing from UNODC. Applications for such permission, with a statement of purpose and intent of the reproduction, should be addressed to the Research and Trend Analysis Branch of UNODC. DISCLAIMER The content of this publication does not necessarily reflect the views or policies of UNODC or contributory organizations, nor does it imply any endorsement. Comments on the report are welcome and can be sent to: Division for Policy Analysis and Public Affairs United Nations Office on Drugs and Crime PO Box 500 1400 Vienna Austria Tel: (+43) 1 26060 0 Fax: (+43) 1 26060 5827 E-mail: [email protected] Website: www.unodc.org/wdr2019 PREFACE The findings of this year’s World Drug Report fill in same time clamping down on organized crime and and further complicate the global picture of drug trafficking. -
Do You Know... Cocaine
Do You Know... Street names: blow, C, coke, crack, flake, freebase, rock, snow Cocaine What is cocaine? Cocaine is a stimulant drug. Stimulants make people feel more alert and energetic. Cocaine can also make people feel euphoric, or “high.” Pure cocaine was first isolated from the leaves of the coca bush in 1860. Researchers soon discovered that cocaine numbs whatever tissues it touches, leading to its use as a local anesthetic. Today, we mostly use synthetic anesthetics, rather than cocaine. In the 1880s, psychiatrist Sigmund Freud wrote scientific papers that praised cocaine as a treatment for many ailments, including depression and alcohol and opioid addiction. After this, cocaine became widely and legally available in patent medicines and soft drinks. As cocaine use increased, people began to discover its dangers. In 1911, Canada passed laws restricting the importation, manufacture, sale and possession of cocaine. The use of 1/4 © 2003, 2010 CAMH | www.camh.ca cocaine declined until the 1970s, when it became known How does cocaine make you feel? for its high cost, and for the rich and glamorous people How cocaine makes you feel depends on: who used it. Cheaper “crack” cocaine became available · how much you use in the 1980s. · how often and how long you use it · how you use it (by injection, orally, etc.) Where does cocaine come from? · your mood, expectation and environment Cocaine is extracted from the leaves of the Erythroxylum · your age (coca) bush, which grows on the slopes of the Andes · whether you have certain medical or psychiatric Mountains in South America. -
Section 124.401 (31, 2) §124.401, CONTROLLED SUBSTANCES 2
1 CONTROLLED SUBSTANCES, §124.401 124.401 Prohibited acts — manufacture, delivery, possession — counterfeit substances, simulated controlled substances, imitation controlled substances — penalties. 1. Except as authorized by this chapter, it is unlawful for any person to manufacture, deliver, or possess with the intent to manufacture or deliver, a controlled substance, a counterfeit substance, a simulated controlled substance, or an imitation controlled substance, or to act with, enter into a common scheme or design with, or conspire with one or more other persons to manufacture, deliver, or possess with the intent to manufacture or deliver a controlled substance, a counterfeit substance, a simulated controlled substance, or an imitation controlled substance. a. Violation of this subsection, with respect to the following controlled substances, counterfeit substances, simulated controlled substances, or imitation controlled substances, is a class “B” felony, and notwithstanding section 902.9, subsection 1, paragraph “b”, shall be punished by confinement for no more than fifty years and a fine of not more than one million dollars: (1) More than one kilogram of a mixture or substance containing a detectable amount of heroin. (2) More than five hundred grams of a mixture or substance containing a detectable amount of any of the following: (a) Coca leaves, except coca leaves and extracts of coca leaves from which cocaine, ecgonine, and derivatives of ecgonine and their salts have been removed. (b) Cocaine, its salts, optical and geometric isomers, or salts of isomers. (c) Ecgonine, its derivatives, their salts, isomers, or salts of isomers. (d) Any compound, mixture, or preparation which contains any quantity of any of the substances referred to in subparagraph divisions (a) through (c). -
Antibacterial Activity of the Five South African Erythroxylaceae Species
African Journal of Biotechnology Vol. 10(55), pp. 11511-11514, 21 September, 2011 Available online at http://www.academicjournals.org/AJB 5hL !W. ISSN 1684–5315 © 2011 Academic Journals Full Length Research Paper Antibacterial activity of the five South African Erythroxylaceae species De Wet, H. Department of Botany, University of Zululand, Private Bag X1001, KwaDlangezwa, 3886, South Africa. E-mail: [email protected]. Tel: +27-35-9026108. Fax: +27-35-9026491. Accepted 21 July, 2011 Until recently, no medicinal uses were recorded for the South African Erythroxylaceae species, although, this family is used world wide in traditional medicine. This study reveals for the first time that Erythroxylum delagoense and Erythroxylum pictum roots were used to treat dysentery and diarrhoea and that Erythroxylum emarginatum leaves decoction was used to treat asthma, kidney problems, arthritis, child bearing problems and influenza in South Africa. To validate some of the medicinal uses, antibacterial testing was done for the first time on all five South African species. Leaf and bark extracts of four of the five South African Erythroxylaceae species (E. delagoense, E. emarginatum, E. pictum and Nectaropetalum capense) showed some good antibacterial activities with MIC <1 mg/ml. E. delagoense showed good results against Bacillus subtilis, Klebsiella pneumoniae and Staphylococcus aureus; E. emarginatum against Klebsiella pneumoniae; E. pictum against Bacillus subtilis and Klebsiella pneumonia; N. capense against Klebsiella pneumonia. Key words: Antimicrobial activity, Erythroxylaceae, medicinal uses, South Africa. INTRODUCTION The Erythroxylaceae family comprises four genera and ent-dolabr-4(18)-en-15S,16-diol, ent-5-dolabr-4(18)-en- 260 species. -
Tropane and Granatane Alkaloid Biosynthesis: a Systematic Analysis
Office of Biotechnology Publications Office of Biotechnology 11-11-2016 Tropane and Granatane Alkaloid Biosynthesis: A Systematic Analysis Neill Kim Texas Tech University Olga Estrada Texas Tech University Benjamin Chavez Texas Tech University Charles Stewart Jr. Iowa State University, [email protected] John C. D’Auria Texas Tech University Follow this and additional works at: https://lib.dr.iastate.edu/biotech_pubs Part of the Biochemical and Biomolecular Engineering Commons, and the Biotechnology Commons Recommended Citation Kim, Neill; Estrada, Olga; Chavez, Benjamin; Stewart, Charles Jr.; and D’Auria, John C., "Tropane and Granatane Alkaloid Biosynthesis: A Systematic Analysis" (2016). Office of Biotechnology Publications. 11. https://lib.dr.iastate.edu/biotech_pubs/11 This Article is brought to you for free and open access by the Office of Biotechnology at Iowa State University Digital Repository. It has been accepted for inclusion in Office of Biotechnology Publicationsy b an authorized administrator of Iowa State University Digital Repository. For more information, please contact [email protected]. Tropane and Granatane Alkaloid Biosynthesis: A Systematic Analysis Abstract The tropane and granatane alkaloids belong to the larger pyrroline and piperidine classes of plant alkaloids, respectively. Their core structures share common moieties and their scattered distribution among angiosperms suggest that their biosynthesis may share common ancestry in some orders, while they may be independently derived in others. Tropane and granatane alkaloid diversity arises from the myriad modifications occurring ot their core ring structures. Throughout much of human history, humans have cultivated tropane- and granatane-producing plants for their medicinal properties. This manuscript will discuss the diversity of their biological and ecological roles as well as what is known about the structural genes and enzymes responsible for their biosynthesis. -
Turning Over a New Leaf: a Subnational Analysis of 'Coca Yes
Journal of Latin American Studies (2021), 53, 573–600 doi:10.1017/S0022216X21000456 ORIGINAL ARTICLE Turning Over a New Leaf: A Subnational Analysis of ‘Coca Yes, Cocaine No’ in Bolivia Susan Brewer-Osorio* Assistant Professor, Latin American Studies, University of Arizona *Corresponding author. Email: [email protected] (Received 9 October 2019; revised 14 April 2021; accepted 19 April 2021; first published online 16 June 2021) Abstract International pressure to suppress cocaine trafficking sustained decades of harsh drug laws in Bolivia against cocaleros (coca producers), thus affecting coca production for traditional consumption and for manufacturing illicit cocaine. These harsh drug laws caused social unrest in cocalero communities outside traditional coca zones. President Evo Morales, leader of the Movimiento al Socialismo (Movement toward Socialism, MAS) party, implemented ‘Coca Yes, Cocaine No’ (CYCN), a harm-reduction strategy that authorised ‘non-traditional’ farmers to cultivate legal coca and self-police production. This article compares CYCN outcomes in Bolivia’s traditional and non-traditional coca regions and finds that strong cocalero organisations were vital to CYCN success in non-traditional areas. In contrast, organised resistance in traditional zones restricted CYCN success and added to regime instability in the lead-up to Morales’ forced resignation in 2019. Hence, while Morales harnessed state power to change drug policy, he was constrained by the rural grassroots organisations that brought him to power. -
1.2 Coca / Cocaine Market
1.2 Coca / cocaine market 1.2.1 Summary trend overview 1.2.2 Production Cultivation In 2008, a significant decrease in Colombia, the world’s In 2008, the total area under coca cultivation decreased largest cultivator of coca bush, brought the total area by 8% due to a significant reduction in Colombia under coca cultivation down by some 8% to 167,600 (-18%), which was not offset by small increases in the ha. Total cultivation is close to the average level since Plurinational State of Bolivia (6%) and Peru (4%). The 2002, and well below the levels reached in the 1990s. total area under coca cultivation decreased to 167,600 Similarly, the estimated global cocaine production also ha, which is well below the level reached in the 1990s. decreased in 2008, due to a strong reduction in Colom- In spite of this decrease, Colombia remained the world’s bia. The Plurinational State of Bolivia and Peru both largest coca bush-cultivating country with 81,000 ha, registered small increases in cultivation and produc- followed by Peru (56,100 ha) and Bolivia (30,500 ha). tion. Most of the decrease of 18,000 ha in Colombia hap- Compared to the record high in 2005, cocaine seizures pened in the regions of Meta-Guaviare and Putumayo- decreased in 2007. The Americas account for the vast Caquetá. However, a significant increase was observed in majority of the world’s cocaine seizures, although a sig- the Pacific region as well as in some smaller cultivation nificant decline in trafficking towards North America, regions. -
Bolivia's Divisions
BOLIVIA'S DIVISIONS: TOO DEEP TO HEAL? 6 July 2004 Latin America Report N°7 Quito/Brussels TABLE OF CONTENTS EXECUTIVE SUMMARY AND RECOMMENDATIONS................................................. i I. INTRODUCTION .......................................................................................................... 1 II. HISTORICAL SYNOPSIS ............................................................................................ 2 III. THE MESA ADMINISTRATION ............................................................................... 4 IV. THE POLITICAL AND SOCIAL OPPOSITION ...................................................... 7 A. EVO'S EVOLUTION AND THE MAS TODAY...............................................................................7 B. LABOUR ORGANISATIONS: THE STREET-BASED OPPOSITION.................................................8 C. OTHER POLITICAL PARTIES...................................................................................................9 D. THE CATHOLIC CHURCH AND NGOS ..................................................................................10 V. SPARKS THAT COULD SET THE COUNTRY AFLAME ................................... 11 A. NATURAL GAS ....................................................................................................................13 B. CAMBAS AND COLLAS ........................................................................................................14 C. THE COCA LEAF .................................................................................................................17