DOCSLIB.ORG

Annual Report 2018 CORPORATE INFORMATION

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Annual Report 2018 CORPORATE INFORMATION 2018 ANNUAL REPORT Genscript Biotech Corporation (the “Company” or “Genscript”, together with its subsidiaries referred to as the “Group”) is a well-established global biotech company, which has consolidated its leading position in the gene synthesis service market with recognized stature in synthetic biology application areas . The Company’s mission is to “Make the Human and Nature Healthier through Biotechnology” by establishing a leading innovative protein and antibody engineering platform and striving for opportune breakthroughs in the fields of cell and gene therapies and industrial enzymes for the benefit of mankind. The Group is a well-recognised life sciences research and application service and product provider that applies its proprietary technology to various fields from basic life sciences research to translational biomedical development, industrial synthetic products, and cell therapeutic solutions. The broad and integrated life sciences research and application service and product portfolio comprises four segments that are all incubated internally, deeply rooted in our proprietary gene synthesis technology and strongly supported by our advanced protein and antibody engineering competence, namely, (i) bio-science services and products, (ii) biologics development services, (iii) industrial synthetic biology products, and (iv) cell therapy. The bio-science services and products are primarily used by scientists and researchers for conducting fundamental life sciences research, translational biomedical research, and early stage pharmaceutical development. Its biologics development services are used by biopharmaceutical and biotech companies for the development of therapeutic antibodies, and gene or cell therapy products with an integrated platform. Its synthetic biology products are used by industry users of industrial enzymes, such as those in the food and feed industries. Its cell therapy products are used to treat refractory diseases including cancer and inflammatory diseases. Since synthetic biology is backed by gene synthesis and editing technology, it falls under the Group’s professional expertise. The Group has made significant progress in its synthetic biology research and application areas, which mainly materialised into its innovative chimeric antigen receptor (“CAR”) T-cell (“CAR-T”) therapy and industrial enzyme businesses. With a strong sales and marketing team and strong research and development capabilities, the Company maintains a stable and sustainable growth. CONTENTS Corporate Profile 2 Corporate Information 3 Financial Highlight 5 Five-year Financial Summary 6 Chairman’s Statement 7 Management’s Discussion and Analysis 11 Directors and Senior Management 23 Report of the Directors 31 Corporate Governance Report 63 Environmental, Social and Governance Report 78 Independent Auditor’s Report 126 Consolidated Statement of Profit or Loss 131 Consolidated Statement of Comprehensive Income 132 Consolidated Statement of Financial Position 133 Consolidated Statement of Changes in Equity 135 Consolidated Statement of Cash Flows 137 Notes to Financial Statements 139 CORPORATE PROFILE GenScript Biotech Corporation (the “Company” or “GenScript”, together with its subsidiaries, the “Group”) is a well-recognised life sciences research and application service and product provider that applies its proprietary technology to various fields from basic life sciences research to translational biomedical development, biologics development services, industrial synthetic products, and cell therapeutic solutions. We maintain our world market leadership in the global gene synthesis service market with recognised stature in synthetic biology. Our broad and integrated life sciences research and application service and product portfolio comprises four segments, namely, (i) bio-science services and products, (ii) biologics development services, (iii) industrial synthetic biology products, and (iv) cell therapy. For the year ended December 31, 2018, we had generated approximately US$141.0 million, US$20.7 million, US$17.7 million, and US$51.6 million from our four segments, representing approximately 61.0%, 9.0%, 7.7%, and 22.3% of our total revenue, respectively. With a strong sales and marketing team and strong research and development capabilities, the Company maintains a stable and sustainable growth. Through 16 years of effort since we were originally founded in New Jersey, the United States in 2002, “GenScript” is now recognised as a well-known and trusted brand underpinned by its high quality life sciences research and application services and products and its synthetic biology application fields in cell therapeutical solutions and its industrial enzyme products. (i) Our bioscience services and products are primarily provided to scientists and researchers for conducting fundamental life sciences research to “Make Research Easy”; (ii) our biologics development services are provided to biotech and biopharma companies to “Speed Up Drug Discovery and Development Process” by utilizing our proprietary platform technology. Both of these two type of services business are operated under the brand “GenScript” that has become well-recognized by the global customer community; (iii) our synthetic biology products are consumed by industry users. Currently, we concentrate on providing high quality industrial enzymes products to customers in the food and feed industries under the brand “Bestzyme” that has gained its reputation in the market resulted from its capability to “Make the Best Enzymes”; and (iv) our cell therapy business is “Pursuing A Cure” to malicious cancers and infectious diseases operated under the brand “Legend Biotech” that has become well known due to its CAR-T cell therapy product “LCAR-B38M” that provides a potential curable solution to refractory multiple myeloma. As of December 31, 2018, we had engendered the trust and confidence of a broad and diverse customer base, including pharmaceutical and biotech companies, colleges and universities, research institutes, government bodies (including government testing and diagnostic centres), and distributors. As of December 31, 2018, over 35,200 international peer-reviewed journal articles had cited the use of our life sciences research and application services and products, among which many leading scientists and researchers in life sciences research industries were indicated to be frequent users of our services and products. For the year ended December 31, 2018, our sales to such categories of customers generated approximately 71.6%, 14.7%, 5.9%, 3.7%, and 4.1% of our total revenue, respectively. We have established an extensive direct sales network, reaching over 100 countries in North America, Europe, the PRC, Japan, and the other Asia Pacific regions. We primarily sell our life sciences research and application services and products through our own direct sales force to our customers worldwide, while we also sell our services and products through independent third-party distributors to expand our market presence and facilitate communication with end users. For the year ended December 31, 2018, we had generated approximately US$132.7 million, US$48.0 million, US$18.5 million, US$12.9 million, US$4.4 million, and US$14.5 million from our sales to customers in North America, the PRC, Europe, Asia Pacific (excluding the PRC and Japan), Japan, and others, representing approximately 57.4%, 20.8%, 8.0%, 5.6%, 1.9%, and 6.3% of our total revenue, respectively. 2 Genscript Biotech Corporation Annual Report 2018 CORPORATE INFORMATION BOARD OF DIRECTORS SANCTIONS RISK CONTROL COMMITTEE Executive Directors Dr. Zhang Fangliang (Chairman) Ms. Wang Ye Dr. Zhang Fangliang (Chairman and Mr. Meng Jiange Chief Executive Officer) Mr. Eric Wang Ms. Wang Ye (President) Mr. Shawn Wu Mr. Meng Jiange (Vice President of Investor Relations) COMPANY SECRETARY Non-Executive Directors Ms. Wong Wai Ling Dr. Wang Luquan Mr. Pan Yuexin AUTHORISED REPRESENTATIVES Ms. Wang Jiafen Dr. Zhang Fangliang Independent Non-Executive Directors Mr. Meng Jiange Mr. Guo Hongxin HONG KONG LEGAL ADVISERS Mr. Dai Zumian Mr. Pan Jiuan Jones Day 31/F Edinburgh Tower AUDIT COMMITTEE The Landmark 15 Queen’s Road Central Mr. Dai Zumian (Chairman) Hong Kong Mr. Pan Jiuan Mr. Guo Hongxin AUDITOR REMUNERATION COMMITTEE Ernst & Young Certified Public Accountants Mr. Guo Hongxin (Chairman) 22/F, CITIC Tower Ms. Wang Ye 1 Tim Mei Avenue Mr. Dai Zumian Central NOMINATION COMMITTEE Hong Kong Dr. Zhang Fangliang (Chairman) REGISTERED OFFICE IN THE CAYMAN Mr. Pan Jiuan ISLANDS Mr. Dai Zumian 4th Floor, Harbour Place 103 South Church Street, George Town P.O. Box 10240, Grand Cayman KY1-1002 Cayman Islands Genscript Biotech Corporation Annual Report 2018 3 CORPORATE INFORMATION HEADQUARTERS AND PRINCIPAL PLACE OF PRINCIPAL BANKS BUSINESS IN THE PRC Bank of America, N.A. Hong Kong Branch No. 28, Yongxi Road 20th Floor, Tower 2 Jiangning Science Park Kowloon Commerce Centre Nanjing 51 Kwai Cheong Road Jiangsu Province Kwai Chung PRC Hong Kong PRINCIPAL PLACE OF BUSINESS IN Bank of America Scotch Plains Office HONG KONG 336 Park Avenue 40th Floor, Sunlight Tower Scotch Plains No. 248 Queen’s Road East NJ 07076 Wanchai USA Hong Kong Yueyahu Branch of China Merchant Bank PRINCIPAL SHARE REGISTRAR AND TRANSFER OFFICE No. 88, Mu Xu Yuan Street Nanjing Harneys Services (Cayman) Limited PRC 4th Floor, Harbour Place 103 South Church Street, George Town COMPANY WEBSITES P.O. Box 10240, Grand Cayman KY1-1002 Cayman Islands www.genscript.com
Load more

Recommended publications
  • Genscript Product Catalog 2013-2014 Genscript Product Catalog
    GenScript Product Catalog 2013-2014 GenScript Product Catalog www.genscript.com GenScript USA Inc. 860 Centennial Ave. Piscataway, NJ 08854USA Tel: 1-732-885-9188 / 1-732-885-9688 Toll-Free Tel: 1-877-436-7274 Fax: 1-732-210-0262 / 1-732-885-5878 Email: [email protected] Nucleic Acid Purification and Analysis Business Development Tel: 1-732-317-5088 PCR PCR and Cloning Email: [email protected] Protein Analysis Antibodies 2013-2014 Peptides Welcome to GenScript GenScript USA Incorporation, founded in 2002, is a fast-growing biotechnology company and contract research organization (CRO) specialized in custom services and consumable products for academic and pharmaceutical research. Built on our assembly-line mode, one-stop solutions, continuous improvement, and stringent IP protection, GenScript provides a comprehensive portfolio of products and services at the most competitive prices in the industry to meet your research needs every day. Over the years, GenScript’s scientists have developed many innovative technologies that allow us to maintain our position at the cutting edge of biological and medical research while offering cost-effective solutions for customers to accelerate their research. Our advanced expertise includes proprietary technology for custom gene synthesis, OptimumGeneTM codon optimization technology, CloneEZ® seamless cloning technology, FlexPeptideTM technology for custom peptide synthesis, BacPowerTM technology for protein expression and purification, T-MaxTM adjuvant and advanced nanotechnology for custom antibody production, as well as our ONE-HOUR WesternTM detection system and eStain® protein staining system. GenScript offers a broad range of reagents, optimized kits, and system solutions to help you unravel the mysteries of biology. We also provide a comprehensive portfolio of customized services that include Bio-Reagent, Bio-Assay, Lead Optimization, and Antibody Drug Development which can be effectively integrated into your value chain and your operations.
    [Show full text]
  • (12) United States Patent (10) Patent No.: US 9,353,350 B2 Kobayashi Et Al
    US009353350B2 (12) United States Patent (10) Patent No.: US 9,353,350 B2 Kobayashi et al. (45) Date of Patent: May 31, 2016 (54) METHOD FOR PRODUCING MULTIPOLAR 2012fO149053 A1 6, 2012 Yoshida et al. CELL 2013,0323,776 A1 12/2013 Yoshida et al. 2015. OO18286 A1* 1/2015 Kobayashi et al. .......... 514, 19.3 (71) Applicant: TOAGOSEICO.,LTD., Tokyo (JP) FOREIGN PATENT DOCUMENTS (72) Inventors: Nahoko Kobayashi, Tsukuba (JP); CN 1763O82 A 4/2006 Tetsuhiko Yoshida, Tsukuba (JP); Yuki DE 102009021681 A1 11, 2010 Kobayashi, Fujisawa (JP) WO O3O24408 A2 3, 2003 WO O3O37172 A2 5, 2003 WO 2004.005472 A2 1, 2004 (73) Assignee: TOAGOSEICO. LTD., Tokyo (JP) WO 2004/020457 A2 3, 2004 WO 2007/004869 A2 1, 2007 (*) Notice: Subject to any disclaimer, the term of this WO 2007056188 A1 5/2007 patent is extended or adjusted under 35 WO 2008/081812 A1 T 2008 WO WO 2009,093692 A1 T 2009 U.S.C. 154(b) by 0 days. WO WO 2011/O13698 A1 2, 2011 (21) Appl. No.: 14/366,971 WO WO 2011/O13699 A1 2, 2011 (22) PCT Filed: Dec. 20, 2012 OTHER PUBLICATIONS Paradis-Bleau et al., “Peptide inhibitors of the essential cell division (86). PCT No.: PCT/UP2O12AO83110 protein FtsA'. Protein Engineering, Design & Selection, 2005, pp. S371 (c)(1), 85-91, vol. 18, No. 2, Oxford University Press. (2) Date: Jun. 19, 2014 Paradis-Bleau et al., “Identification of Pseudomonas aeruginosa FtsZ. peptide inhibitors as a tool for development of novel antimicro bials”, Journal of Antimicrobial Chemotherapy, Jun. 2004, pp.
    [Show full text]
  • Peptide Handbook a Guide to Peptide Design and Applications in Biomedical Research
    Peptide Handbook A Guide to Peptide Design and Applications in Biomedical Research First Edition www.GenScript.com GenScript USA Inc. 860 Centennial Ave. Piscataway, NJ 08854 USA Phone: 1-732-885-9188 Toll-Free: 1-877-436-7274 Fax: 1-732-885-5878 Table of Contents The Universe of Peptides Reliable Synthesis of High-Quality Peptides Molecular structure 3 by GenScript Characteristics 5 Categories and biological functions 8 Analytical methods 10 Application of Peptides Research in structural biology 12 Research in disease pathogenesis 12 Generating antibodies 13 FlexPeptideTM Peptide Synthesis Platform which takes advantage of the latest Vaccine development 14 peptide synthesis technologies generates a large capacity for the quick Drug discovery and development 15 synthesis of high-quality peptides in a variety of lengths, quantities, purities Immunotherapy 17 and modifications. Cell penetration-based applications 18 Anti-microorganisms applications 19 Total Quality Management System based on multiple rounds of MS and HPLC Tissue engineering and regenerative medicine 20 analyses during and after peptide synthesis ensures the synthesis of Cosmetics 21 high-quality peptides free of contaminants, and provides reports on peptide Food industry 21 solubility, quality and content. Synthesis of Peptides Diverse Delivery Options help customers plan their peptide-based research Chemical synthesis 23 according to their time schedule and with peace of mind. Microwave-assisted technology 24 ArgonShield™ Packing eliminates the experimental variation caused by Ligation technology 26 oxidization and deliquescence of custom peptides through an innovative Recombinant technology 28 Modifications packing and delivery technology. 28 Purification 30 Expert Support offered by Ph.D.-level scientists guides customers from Product identity and quality control 31 peptide design and synthesis to reconstitution and application.
    [Show full text]
  • CEM Peptide Synthesis Brochure
    Unparalleled Peptide Synthesis cempeptides.com Contents CEM Overview 2 Innovations in Microwave Peptide Synthesis 2 Founding Fathers 3 Corporate Legacy Chemistry Technologies 4 HE-SPPS 6 CarboMAXTM 8 One Pot Coupling/Deprotection Peptide Synthesizers 10 Sequential vs Parallel 11 Synthesizer Comparison 12 Discover BioTM 12 Liberty LiteTM 13 Liberty BlueTM 13 Liberty Blue HT12TM 14 Liberty PRIMETM 16 Accessories & Upgrades Peptide Cleavage 17 Razor® SPPS Reagents 18 Fmoc Amino Acids 19 Oxyma Pure 19 Resins (ProTide™, Polystyrene) Large Scale Microwave Peptide Synthesis 22 Liberty PRO™ Customers 24 Testimonials 25 Support CEM Overview Innovations in Microwave Peptide Synthesis 1978 CEM Corporation founded as a new company, based on microwave laboratory instrumentation 2001 CEM launches a single mode microwave system for chemical synthesis 2003 CEM develops the world’s first automated microwave peptide synthesizer1 2007 CEM publishes research for optimized methods for aspartimide formation and epimerization under microwave SPPS2 2013 Liberty Blue™ peptide synthesizer developed based on High Efficiency Solid Phase Peptide Synthesis (HE-SPPS) 2014 HE-SPPS methodology published3 2016 CEM launches new universal load resins eliminating the need for pre-loaded resins historically used 2016 CEM offers the world’s first large-scale microwave peptide synthesis, with capabilities of up to 500 grams of a purified peptide, in a single batch 2016 CEM develops improved carbodiimide coupling methods for peptide synthesis at elevated temperature (CarboMAX™) 2017 CEM develops a novel one-pot coupling/ deprotection process reducing SPPS cycle time and waste usage (Liberty PRIME™) Founding Fathers (circa 1980) Chemist: Dr. Michael J. Collins (Middle) Electrical Engineer: Ron Goetchius (Left) Mechanical Engineer: Bill Cruse Jr.
    [Show full text]
  • United Kingdom
    UNITED KINGDOM A & D Instruments Ltd Abertec Ltd Adams Business Associates Abingdon Science Park, Abingdon, Oxford OX 14 Old College King St, Aberystwyth, Dyfed SY23 Kelvin House, Totteridge Ave, High Wycombe, 3YS. 2AX. Bucks HP\3 6XG. Tel: 0235 5504201 0800 616140 Tel: 0970 622385 Telex: 35181 aby ucw Tel: 0494 465244 Fax: 0494 446788 Fax: 0235 550485 Fax: 0970 622959 Offer services in biotechnology including Supply semi-micro, analytical, general, industrial Involved in technology transfer from University of international market analysis, management and and moisture balances as well as density meters. Wales Aberystwyth. Capabilities include genetics, implementation of projects (including mergers and genetic engineering, bioproducts and acquisitions) and business development and biotransformations, biochemistry, plant and animal marketing programmes. Subsidiary offices now & A J Beveridge metabolism, biomass measurement, biosensing, established in Belguim, France and Spain. 5 Bonnington Road Lane, Leith, Edinburgh EH6 process control, tissue culture. Also undertakes 5BP. consultancy and collaborative research. Tel: 031 5535555 Fax: 031 5546068 ADC Systems Supply laboratory products. Gronant, Caernarfon, Gwynedd LL54 5BY. ABR Foods Ltd Tel: 0286 77148 Sallow Road, Weldon Industrial Estate, Corby Designs and manufactures analytical and Aaston Ltd NorthantsNNI7 \JX. preparative equipment for pathology laboratories Tel: 0536 65291 Telex: 34695 3 Abbas Business Centre, Itchen Abbas, Winchester, based on photometric determinations and robotic Fax: 0536 402228 HampshireS021IBQ. systems. Tel: 0980 6\0 391 Fax: 0980 610 898 Process wheat for the production of vital gluten as See Aaston Inc, MA, US. well as producing other related starch products, syrups and animal feed ingredients. Investigating ADM Ingredients Ltd opportunities for production of fermentation Church Manorway, Erith, Kent DA8 I DL.
    [Show full text]
  • Download Full Custom Synthetic Peptide Production
    CSPP SERVICES Version 13MY15 SYNTHETIC PEPTIDE PRODUCTION CUSTOMER INFORMATION PACKAGE Toll free: 1-866-KINEXUS or 604-323-2547 Facsimile: 604-323-2548 E-mail: [email protected] www.kinexus.ca TABLE OF CONTENTS Custom Synthetic Peptide Production (CSPP) Services PDF Page No. 1. Introduction ………………………………………………………………………….…………. 3 Ser vice Ordering Information 2. Turnaround Time ………………………………………...……………………………………. 4 3. Pricing Information ……………………………………………………………………………. 4 4. Forms to be Completed ……………………………….......................................…………. 5 Follow Up Services 5. Related and Follow Up Services …………………………………………………………... 6 Appendices - Forms to Complete and Return with Your Order 6. Service Order Form (CPAP-SOF) ……………………………………………………….... 8 7. CSPP1-SIF Form - Custom Synthetic Peptide Production ………………….….......… 9 8. CSPP2-SIF Form - Custom Synthetic Peptide Mass Production ………..…….......… 10 9. Kinexus Proteomics Services Agreement …………………………............……………. 11 13MY15-Custom Synthetic Peptide Production Services 2 Kinexus Bioinformatics Corporation Customer Information Package Custom Peptide Array Production (CPAP) Services 1. INTRODUCTION As an important component of our unique integrated suite of proteomics services, Kinexus is pleased to offer custom peptide synthesis to assist our clients in their discovery programs. Peptides are useful tools for the development of antibodies, substrates and probing protein- protein and drug-protein interactions. This package contains all of the information and forms required for our clients
    [Show full text]
  • Conferencebookletfinal.Pdf
    Custom Peptide Synthesis & cGMP Peptide Production Fully Licensed 0VSD(.1QFQUJEFQSPEVDUJPOGBDJMJUZJT'%"-JDFOTFEBOE NBJOUBJOTB%SVH.BOVGBDUVSJOH-JDFOTFJTTVFECZUIF4UBUF PG $BMJGPSOJB %FQBSUNFOU PG 1VCMJD )FBMUI 4FSWJDFT 'PPE BOE%SVH#SBODI$4#JPJTGVMMZMJDFOTFEBOEFRVJQQFEUP QSPEVDFDMJOJDBMHSBEFQFQUJEFT Dedicated cGMP Facility 0VS BQQSPBDI UP D(.1 .BOVGBDUVSJOH JODMVEFT EFEJDBUJOH BQSPEVDUJPOMJOFBOEUFBNPGDIFNJTUTUPFBDIQSPKFDUćJT JTUPBTTVSFDPOĕEFOUJBMJUZ BWPJEDSPTTDPOUBNJOBUJPOBOEUP TJNQMJGZSFQPSUJOHUPDMJFOUTBOESFHVMBUPSZBHFODJFT Complete cGMP Documentation 8FTVQQMZPVSDMJFOUTXJUIBMMD(.1SFMBUFEEPDVNFOUBUJPO JODMVEJOH#BUDI1SPDFTT3FDPSET 3BX.BUFSJBM$P"TBOEĕ- OBM2$%BUB8FGFFMJUJTJNQFSBUJWFUPXPSLDMPTFMZXJUI PVSDMJFOUTUPNBJOUBJORVBMJUZBOEUPBTTVSFDPNQMJBODF8F XFMDPNFOFXBOEFYJTUJOHDMJFOUTGPSJOTQFDUJPOBOEBVEJUT Peptide Synthesizers R&D Scale Models $49BOE$495 Reaction Vessel Sizes from 10 mL to 250 mL Industrial Scale Models $495BOE$44 $4$49 Reaction Vessel Sizes from 50 mL to 1000 L C S Bio Co. ,FMMZ$PVSU .FOMP1BSL $"64"5FMFQIPOF t'BY 8FCXXXDTCJPDPNt&NBJMQFQUJEFT!DTCJPDPN October 2-5, 2012 Welcome to PEM6 Learning from Nature to Engineer Peptides The co-chairs of the sixth Peptide Engineering Meeting, PEM6, would like to welcome you to Atlanta, Georgia for this exciting international workshop addressing structure-based approaches to peptide design, peptide-protein interactions, peptide-membrane interactions, peptide bioactivity, and peptide- based materials. The theme of this year’s meeting is Learning from Nature to Engineer Peptides. The PEM series
    [Show full text]
  • Chemistry at Munich
    ΤΗΕ EUROPEAN ΡΕΡΤΙΟΕ SOCIETY NEWSLETTER Issue Number 13, 1 April 1996 THEODOR WIELAND (1913 - 1995) Ιn Memoriam It is with deepest sorrow that Ι pick υρ my pen to write ίη tribute to my great friend, and academic father for most of my life, the Iate Theodor Wieland. Theodor passed away οη 24 November 1995. He seemed to be recovering well from an operation, when he relapsed and had to surrender after a short fight for survival. Το his family members, closest friends, and also his many colleagues, this cruel turn of fate was both unexpected and distressing. Only weeks before, the members of the Max-Bergmann-Kreis had met with Theodor ίη the Dolomites for an intimate scientίfic conference. ΑΙΙ had admired his physical strength, sparkling spirit and warm humour, so famous worldwide among the peptide science community. Now, this dear fellow chemist has left us forever. Το me he was a great man of science who had - so rare these days - not only comprehensive intellectual grandeur but also realistic and sound judgement ίη practical matters. Α most gifted and creative natural philosopher, a learned scholar, a man of culture, and a humanitarian with unlimited patience and personal modesty has passed away. His open nature and inability of creating enemies was an obvious aspect of his character; more subtle was his puckish sense of humour, which was frequently exercised among family members and close friends. Name another man of his stature! Professor Dr.phil.nat. , Dr.h.c. Hermann Theodor Felix Wieland was born 5 June 1913 in Munich, son of Nobel Laureate Heinrich Wieland.
    [Show full text]
  • 1. Introduction
    Introduction 1. INTRODUCTION........................................................................................ 4 1.1. A BRIEF HISTORY ..........................................................................................................................4 1.2. SOLID PHASE SYNTHESIS ..............................................................................................................6 1.3. SUPPORTS FOR SOLID PHASE SYNTHESIS ....................................................................................7 1.3.1. Styrene-divinylbenzene copolymers................................................................................................8 1.3.2. Polyacrylamides...............................................................................................................................9 1.3.3. Polyethylene glycol (PEG) ............................................................................................................ 10 1.3.4. Silica.............................................................................................................................................. 11 1.3.5. Other Supports............................................................................................................................... 12 1.4. ANALYTICAL METHODS ..............................................................................................................13 1.4.1. Combustion analysis...................................................................................................................... 13 1.4.2.
    [Show full text]
  • Service Brochure
    GenScript Your Innovation Partner in Drug Discovery! Service GenScript The Biology CRO Biological Service Guide Bio-Reagent Center Contact Us Gene Services Protein Services GenScript is dedicated to serving pharmaceutical, biotech, and academic customers in the areas of drug discovery, development, GenScript Biological Service Guide Peptide Services and life science research. With a global presence and local access, GenScript provides high-quality biology CRO services and Antibody Services around-the-clock account support to our customers all over the world. Contact us any time. Cell Line Services Bio-Assay Center Contact: Lead Optimization Center All Correspondence Email: [email protected] GenScript USA Inc. Tel: 1-877-436-7274 (Toll-Free) 120 Centennial Ave. Tel: 1-732-885-9188, 1-732-885-9688 Antibody Drug Piscataway, NJ 08854 Fax: 1-732-210-0262, 1-732-885-5878 Development Center U.S.A. Business Development: Email: [email protected] Tel: 1-732-317-5088 Regional Numbers: Australia: 1-800-172-605 (Toll-Free) Japan: 81-3-6206-8985 Belgium: 32-27-470-921 Netherlands: 31-20-890-5456 2010–2011 Denmark: 8088-7617 (Toll-Free) Norway: 800-19-172 (Toll-Free) France: 08-05-10-22-28 (Toll-Free) Portugal: 800-815-627 (Toll-Free) Finland: 0800-913-020 (Toll-Free) Singapore: 800-120-4549 (Toll-Free) Germany: 0-800-0006-320 (Toll-Free) Spain: 800-098-920 (Toll-Free) Hong Kong: 800-964-684 (Toll-Free) Sweden: 0200-884-573 (Toll-Free) Ireland: 1800-932-547 (Toll-Free) Switzerland: 0800-369-254 (Toll-Free) Israel: 1-809-216-068 (Toll-Free) United Kingdom: 08082-380203 (Toll-Free) 2010–2011 CALL NOW FOR MORE INFORMATION GenScript 1-732-885-9188 The Biology CRO Date Version: 05/14/2010 Fax: 1-732-210-0262 Web: www.genscript.com Email: [email protected] Your Innovation Partner in Drug Discovery! Table of Contents Service Overview ...............................................................................................
    [Show full text]
  • Reagents and Custom Solutions for Immunodiagnostic Assay Development Naming Convention on Links Need to Be Addressed Before Releasing to Client
    Reagents and custom solutions for immunodiagnostic assay development Naming convention on links need to be addressed before releasing to client. Double check color standards and fonts in graphs should all be Helvetica Neue not Universe. Contents Introduction 3 Linking mechanisms 40 Crosslinkers 40 Capture surfaces 5 PEGylation reagents 47 Magnetic beads 5 Biotinylation reagents 49 Latex beads 10 Biotin quantitation kits 53 Coated multiwell plates 13 Pierce premium grade reagents 54 Custom plate coating service 17 Fluorescent antibody and protein 56 Biotin-binding proteins 18 labeling kits Fluorescent dyes 58 Enzyme labeling kits 63 Antibodies and detection probes 20 Primary antibodies 21 ABfinity recombinant antibodies 23 Nonspecific binding 65 Secondary antibodies 25 Blocking buffers 65 Fluorescent and 25 Wash buffers 68 enzyme-conjugated Detergents 70 secondary antibodies Protein stabilizers 71 Superclonal 26 secondary antibodies CaptureSelect affinity ligands 27 Detection substrates 72 Custom antibody development and 29 Chemiluminescent substrates 73 production services Colorimetric substrates for 78 ELISA products 32 AP and HRP ELISA kits 32 Fluorescent substrates 80 Antibody pair kits 33 Biotin-binding protein conjugates 34 Manufacturing capabilities 81 Introduction Who understands your We see companies juggling costs, assay development time, and assay quality, which forces them to focus on challenges? We do. certain aspects while sacrificing others. This balancing act can result in failures to fully maximize proprietary Immunodiagnostic assay technology or delays to market, but assay development development and commercialization doesn’t have to be this way. are challenging and time- Then there are the other obstacles that you might face. What if you hit a reliability issue with the raw materials used consuming.
    [Show full text]
  • Unnatural Amino Acids Mir027 a Market Insight Report– July 2010
    UNNATURAL AMINO ACIDS MIR027 A MARKET INSIGHT REPORT– JULY 2010 CONTENTS 1. SCOPE AND METHODOLOGY .......................................................................................................................... 1 2. REPORT SYNOPSIS ......................................................................................................................................... 4 Unnatural Amino Acids – An Introduction ............................................................................................................................. 4 Amino Acids ........................................................................................................................................................................... 5 Types of Amino Acids ......................................................................................................................................................... 6 Essential Amino Acids ..................................................................................................................................................... 6 Non‐Essential Amino Acids ............................................................................................................................................. 6 Proteinogenic Amino Acids ............................................................................................................................................ 6 Non‐Proteinogenic Amino Acids....................................................................................................................................
    [Show full text]