What's Inside
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Newsletter A publication of the Controlled Release Society Volume 32 • Number 1 • 2015 What’s Inside 42nd CRS Annual Meeting & Exposition pH-Responsive Fluorescence Polymer Probe for Tumor pH Targeting In Situ-Gelling Hydrogels for Ophthalmic Drug Delivery Using a Microinjection Device Interview with Paolo Colombo Patent Watch Robert Langer Awarded the Queen Elizabeth Prize for Engineering Newsletter Charles Frey Vol. 32 • No. 1 • 2015 Editor Table of Contents From the Editor .................................................................................................................. 2 From the President ............................................................................................................ 3 Interview Steven Giannos An Interview with Paolo Colombo from University of Parma .............................................. 4 Editor 42nd CRS Annual Meeting & Exposition .......................................................................... 6 What’s on Board Access the Future of Delivery Science and Technology with Key CRS Resources .............. 9 Scientifically Speaking pH-Responsive Fluorescence Polymer Probe for Tumor pH Targeting ............................. 10 Arlene McDowell Editor In Situ-Gelling Hydrogels for Ophthalmic Drug Delivery Using a Microinjection Device ........................................................................................................ 12 Patent Watch ................................................................................................................... 14 Special Feature How to Be a Scientist and yet Write a Literary Novel ........................................................ 16 Bozena Michniak-Kohn Chapter News Editor CRS New Zealand Local Chapter (NZCRS) Events in 2014 ................................................ 18 DDTR Updates Drug Delivery and Translational Research (DDTR) ............................................................. 20 People in the News ......................................................................................................... 21 In the News ..................................................................................................................... 23 Yvonne Perrie Calendar of Events Editor .................................................................................................. Cover 4 Advertisers’ Index Drug Delivery and Translational Research ................................................................ Cover 2 18th Microencapsulation Industrial Convention ................................................................ 11 Rod Walker Controlled Release Conference ......................................................................................... 17 Editor Cover image: Human Eye and Target ©Vladyslav Starozhylov / Shutterstock.com 1 From the Editor Editors Charles Frey Steven Giannos Arlene McDowell Arlene McDowell University of Otago Bozena Michniak-Kohn New Zealand Yvonne Perrie Rod Walker Unexpected Things The CRS Newsletter is the official newsletter of the Controlled Release Society. The newsletter is published six ith the start of a new year, thinking can turn to wondering what the year will times annually, providing scientific and hold. iCal, doodle, and deadlines make sure we plan for some of the things we technical information pertinent to the do,W but there will always be unexpected things. controlled release community and news about society and chapter activities. Members can receive the newsletter via Unexpected things can be tragic, and I am reminded of the untimely passing of mail. The newsletter may also be viewed Marcus Brewster—a wonderful friend of so many in CRS. I am sure that Marcus online at controlledreleasesociety.org. would attest that unexpected things can also provide us with a great opportunity to Newsletter articles reflect only the views do something that we would not normally do. Personally, CRS has provided me with of the authors. Publication of articles or opportunities that I did not foresee (including co-editing a book, eating from a advertisements within the CRS Newsletter chocolate fountain in the penthouse at the New York Hilton, and going behind the does not constitute endorsement by the scenes at the Minneapolis zoo to fulfil a long-term wish to meet an opossum). This Controlled Release Society or its agents of products, services, or views expressed has all been through my contribution to CRS committees. Recently, I have been herein. No representation is made as to serving on the CRS Volunteer Recruitment Committee, where we have been looking the accuracy hereof, and the publication at strategies to broaden participation in the operation of CRS as well as enhancing is printed subject to errors and omissions. the volunteer experience. I strongly encourage you to get involved in a CRS Editorial contributions should be committee and see what unexpected things you can encounter. The CRS local directed to the CRS Newsletter Editors, chapters are an excellent way to begin your involvement and can enable you to ([email protected]) and are contribute more than your science to CRS. subject to the terms and conditions of the Editorial and Publication Release. Publisher assumes no responsibility for the In this issue of the CRS Newsletter you can read about a new initiative by the DDTR safety or return of artwork, photographs, journal to now consider publishing research that has a negative or unexpected finding. or manuscripts. This is an excellent initiative, and our lab group has often lamented the lack of this Requests for advertisement placement may type of forum. CRS members get free access to the online journal content. We also be directed to Susan Kohn; telephone have all our regular forums, including Scientifically Speaking, Patent Watch, and an +1.651.994.3812, or e-mail at skohn@ interesting interview with Prof. Paolo Colombo from Universita degli studi di Parma, scisoc.org. All advertisements are subject to “General Conditions of Sale.” Italy. Prof. Gregory Gregoriadis has also written a compelling account of his foray into writing a novel. Unauthorized reproduction in whole or in part is prohibited. Requests for permission Edinburgh is the place to be in 2015 for our CRS Annual Meeting. It seems like should be directed to the Editors at [email protected]. many of you agree, because a record number of abstracts have been submitted for this conference. I am excited to see the new format for the conference closing ©Copyright 2015 Controlled Release reception in Edinburgh. Plan to be there and to be open to the unexpected things Society. All rights reserved. that can happen. Controlled Release Society 3340 Pilot Knob Road St. Paul, MN 55121 U.S.A. On behalf of the CRS Newsletter editorial team, I wish you a happy, healthy, and Telephone: +1.651.454.7250 successful 2015. Facsimile: +1.651.454.0766 I will leave you with a relevant quote from Oscar Wilde: “To expect the unexpected Visit controlledreleasesociety.org or shows a thoroughly modern intellect.” e-mail [email protected] on questions about membership, meetings, publications, and services. Best wishes, n Contact [email protected] for information Arlene McDowell about exhibiting, advertising, or other visibility opportunities. 2 From the President Art Tipton Southern Research Institute Birmingham, Alabama, U.S.A. Celebrate Our History! or many of us, January is the month when we come back You were probably already excited about the meeting in from a brief end-of-the-year break. Like many, I took some Edinburgh. Now you should be even more so given the timeF off as the year ended, reflected on 2014, and spent time opportunity to acknowledge Nicholas. Please also read more at planning for 2015. I unwound with a few books, including All the our website on how you can contribute and be part of this Light We Cannot See, the Anthony Doerr novel set during World opportunity, both to recognize Nicholas’s many accomplishments War II that is currently on best-seller lists, and the final book of in our field and contributions to our society and to invest in the Ken Follett’s Century Trilogy, Edge of Eternity. Those books got next generation of scientists. me thinking about history. As I write this in mid-January, we just commemorated Martin Luther King Jr. Day and reflected on his I want to provide a few more updates on the annual meeting. pivotal role in history. For us in North America, King is the While we appreciate and will build on our great history, as you person most identified with human rights, and he joins Nelson have probably seen from emails and other communications, we Mandela from Africa, Lech Walesa from Europe, Mahatma are working to add some changes so that we have the most Gandhi from Asia, and others around the world who as interactive and enjoyable meeting ever. Many of the leading individuals made a strong historical difference. scientists around the world have seen this updated format and are responding by submitting what looks to be a record-breaking In our own way, we at CRS have a great history we should also number of abstracts. Also, as you know, we will have an increased commemorate. For many years we have acknowledged our leaders industry focus, once again renewing our commitment to that with awards. In 2009 we created a special way to acknowledge the fruitful exchange between academia and industry that has been luminaries in our field with a Foundation Award. In that year and an integral part the rich CRS history. Our annual banquet, once subsequent