UQCRB Antibody Cat. No.: 56-792

UQCRB Antibody

UQCRB Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

This UQCRB antibody is generated from rabbits immunized with a KLH conjugated IMMUNOGEN: synthetic peptide between 19-47 amino acids from the Central region of human UQCRB.

TESTED APPLICATIONS: IHC-P, WB

For WB starting dilution is: 1:1000 APPLICATIONS: For IHC-P starting dilution is: 1:10~50

PREDICTED MOLECULAR 14 kDa WEIGHT:

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This antibody is purified through a protein A column, followed by peptide affinity PURIFICATION: purification.

CLONALITY: Polyclonal

ISOTYPE: Rabbit Ig

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.

CONCENTRATION: batch dependent

Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Additional Info

OFFICIAL SYMBOL: UQCRB

Cytochrome b-c1 complex subunit 7, Complex III subunit 7, Complex III subunit VII, QP-C, ALTERNATE NAMES: Ubiquinol-cytochrome c reductase complex 14 kDa protein, UQCRB, UQBP

ACCESSION NO.: P14927

PROTEIN GI NO.: 136717

GENE ID: 7381

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

This gene encodes a protein which is part of the ubiquinol-cytochrome c oxidoreductase complex which contains ten nuclear-encoded and one mitochondrial-encoded subunits. BACKGROUND: The encoded protein binds ubiquinone and participates in the transfer of electrons when ubiquinone is bound. Mutations in this gene are associated with mitochondrial complex III deficiency. A pseudogene has been described on the X chromosome.

REFERENCES: 1) Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3558-3566(2008)

2) Haut, S., et al. Hum. Genet. 113(2):118-122(2003)

3) Malaney, S., et al. Cytogenet. Cell Genet. 73(4):297-299(1996)

4) Suzuki, H., et al. J. Biol. Chem. 265(14):8159-8163(1990)

ANTIBODIES FOR RESEARCH USE ONLY.

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