Abelmoschus Moschatus Medik
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Review Article [Dwivedi & Argal, 6(7): July, 2015:4657-4660] CODEN (USA): IJPLCP ISSN: 0976-7126 INTERNATIONAL JOURNAL OF PHARMACY & LIFE SCIENCES (Int. J. of Pharm. Life Sci.) A Review on Pharmacological and Phytochemical profile of Abelmoschus moschatus Medik. Abhishek Dwivedi1* and Ameeta Argal2 1, Research Scholar, Institute of Pharmaceutical Sciences and Research, Bhagwant University, Ajmer, RJ- India 2, TIT Pharmacy, Bhopal, M.P-India Abstract Abelmoschus moschatus Medik. is an aromatic and medicinal plant in the Malvaceae family, which is native to India. It is an erect hispid herbaceous trailing herb that grows up to 1.5m tall with a long slender tap root. Leaves are alternate, rough, hairy and heart-shaped. They have 3 to 5 lobes and can grow to 15cm long. Flowers resemble those of the hibiscus and are usually watermelon pink, although they are sometimes white or cream in colour. They last for only one day and their flowering depends on the timing of the wet season. Seeds are contained within hairy capsules up to 8 cm long, which are tough but papery. The seeds have a sweet, flowery, heavy fragrance similar to that of musk. The present paper deals with review on pharmacological and phytochemical profile of Abelmoschus moschatus Medik. Key-words: Abelmoschus moschatus, Pharmacological, Phytochemical Introduction Medicinal plants are living and irreparable resources Flower infusion is contraceptive. Different parts of the that is exhaustible if over used and sustainable if used plant have uses in traditional and complementary with care and wisdom. The importance of medicinal medicine, not all of which have been scientifically plants has been mentioned since ancient time. proven. It is used externally to relieve spasms of the However, at present medicinal plants are looked upon digestive tract, cramp, poor circulation and aching not only as a source of health care but also as a source joints. It is also considered an insecticide and an of income (Dwivedi et al., 2007). These plants aphrodisiac. generated commercial demand for pharmacopoeial In India, roots, leaves (rarely), and seeds of ambrette drugs and their products in India (Dwivedi S., 2014). are considered valuable traditional medicines. The Efforts have been made in recent years to introduce bitter, sweet, acrid, aromatic seeds are used as a tonic many of these drug plants to common people. and are considered cooling, aphrodisiac, opthalmic, Abelmoschus moschatus Medik. is an aromatic and cardiotonic, digestive, stomachic, constipating, medicinal plant in the Malvaceae family, which is carminative, pectoral, diuretic, stimulant, native to India. It is an erect hispid herbaceous trailing antispasmodic, deodorant, and effective against kapha herb that grows up to 1.5m tall with a long slender tap and vata, intestinal complaints, stomatitis; and diseases root. of the heart. According to Unani system of medicine The plant is used in the treatment of various diseases as seeds allay thirst, cure stomatitis, dyspepsia, urinary described in traditional and folk remedies. Every part discharge, gonorrhea, leucoderma and itch. Roots and of this medicinal plant is used in one or the other leaves are cures for gonorrhea (Orwa et al.,; Jain, way. Seeds are effective aphrodisiac and 1991). antispasmodic, and used in tonics. They check The present paper deals with studies on vomiting and are useful in treating intestinal disorders, pharmacological and phytochemical profile of the urinary discharge, nervous disorders, hysteria, skin selected medicinal plant. diseases etc. The mucilaginous seeds are emollients Review on Pharmacological and Phytochemical and demulcents. Profile of Abelmoschus moschatus Medik. A comprehensive review of literature was done to * Corresponding Author study the work done in the selected species and it was E.mail: E.mail: [email protected] found that, several authors reported on pharmacological and phytochemical profile of selected Mob.+91-9893077870 © Sakun Publishing House (SPH): IJPLS 4657 Review Article [Dwivedi & Argal, 6(7): July, 2015:4657-4660] CODEN (USA): IJPLCP ISSN: 0976-7126 species. Chatterjee et al., (2005) studied emollient and Plant Profile antipruritic effect of itch cream in dermatological Botanical Name : Abelmoschus moschatus Medik. disorders: A randomized controlled trial. Liu et al., Family : Malvaceae (2005) investigated myricetin as the active principle of Synonyms : Hibiscus abelmoschus Abelmoschus moschatus to lower plasma glucose in Linn.(Nadkarni, 1927). streptozotocin-induced diabetic rats. Liu et al., (2006) Taxonomic classification studied mediation of β-endorphin by myricetin to lower Kingdom : Plantae plasma glucose in streptozotocin-induced diabetic rats. Phyllum : Angiosperms Krishnaraju (2006) did the biological screening of . Class : Eudicots medicinal plants collected from Eastern Ghats of India . Sub-Class : Rosids using Artemia salina (brine shrimp test). Ngoc et al., . Order : Malvales (2008) investigated hypolipidemic effect of extracts . Family : Malvaceae from Abelmoschus esculentus L. (Malvaceae) on . Genus : Abelmoschus Tyloxapol-Induced hyperlipidemia in Mice. Liu et al., . Species : moschatus (2007) investigated improvement of insulin sensitivity Vernacular Names in obese Zucker rats by myricetin extracted from . English : Muskmallow, Ambrette Abelmoschus moschatus. Liu et al., (2009) studied . Sanskrit : Latakasturika, Gandapura Abelmoschus moschatus (Malvaceae), an aromatic . Hindi : Mushkdana, kasturi bendi, plant, suitable for medical or food uses to improve Kasturidana insulin sensitivity. Maheshwari et al. (2009) . Marathi : Kasthuri bhendi investigated antimicrobial activity of Abelmoschus . Tamil : Varttilaikasturi moschatus leaf extracts. Rival et al., (2009) studied . Telugu : Kasturi benda Hibiscus abelmoschus seed extract as a protective . Kannada : Kasturi bende active ingredient to favour FGF-2 activity in skin. Assamese : Gorukhiakorai Singh et al., (2012) studied evaluation of . Gujarati : Mushkdana hepatoprotective activity of Abelmoschus moschatus . Malyalam : Kasthurivenda seed in paracetamol induced hepatotoxicity on rat. French : Ambretta semi Christina and Muthumani (2012) reported . German : Musk Okra (Nadkarni, 1927). phytochemical investigation and diuretic activity of Part used : Seed, flower, root, leaves Abelmoschus moschatus Medikus Christina and Distribution Muthumani (2013) reported phytochemical It is native of India and is cultivated widely as an oil investigation and anti lithiatic activity of Abelmoschus seed crop in India, Southern China, Vietnam, Nepal, moschatus Medik.Nee et al., (1986) investigated the Tropical Asia, South East Asia and some parts of the seed coat components of Hibiscus abelmoschus. Pacific. Camciuc et al., (1998) studied volatile components in Description okra seed coat. Blunden et al., (2001) studied betaine Abelmoschus moschatus Medik. is an aromatic and distribution in the Malvaceae. Holser et al. (2002) medicinal plant in the Malvaceae family, which is determined the extraction of lipid components from native to India. It is an erect hispid herbaceous trailing seeds of Hibiscus species by supercritical carbon herb that grows up to 1.5m tall with a long slender tap dioxide. Cravo et al., (2006) studied the chemical root. Leaves are alternate, rough, hairy and heart- composition of the essential oil, oleoresin and its shaped. They have 3 to 5 lobes and can grow to 15cm volatile product obtained from ambrette (Abelmoschus long. Flowers resemble those of the hibiscus and are moschatus moench) seeds. Liu et. al., (2007) studied usually watermelon pink, although they are sometimes myricetin, a naturally occurring flavonol, ameliorates white or cream in colour. They last for only one day insulin resistance induced by a high-fructose diet in and their flowering depends on the timing of the wet rats. Du et al. (2008) estimated the volatile organic season. Seeds are contained within hairy capsules up to nitrogen-containing constituents in ambrette 8 cm long, which are tough but papery. The seeds have Abelmoschus moschatus Medik (Malvaceaae). a sweet, flowery, heavy fragrance similar to that of Adelakun et al., (2009) studied chemical composition musk. It can be grown in varied climate under tropical and the anti-oxidative properties of Nigerian Okra Seed and subtropical conditions. It can be grown both as a (Abelmoschus moschatus M.) Flour. rain fed crop and as an irrigated crop. It grows on well-drained loamy and sandy loam soils. Loamy soils with neutral pH and plenty of organic matter are ideal © Sakun Publishing House (SPH): IJPLS 4658 Review Article [Dwivedi & Argal, 6(7): July, 2015:4657-4660] CODEN (USA): IJPLCP ISSN: 0976-7126 for its cultivation (Purohit et al., 2004) It is propagated and an aphrodisiac. In India, roots, leaves (rarely), and through seeds. The optimum time of sowing is June- seeds of ambrette are considered valuable traditional July with pre-monsoon showers. Seeds are soaked in medicines. The bitter, sweet, acrid, aromatic seeds are water before sowing for 24 hours. It takes 5-7 days for used as a tonic and are considered cooling, aphrodisiac, proper germination. opthalmic, cardiotonic, digestive, stomachic, Chemical constituents constipating, carminative, pectoral, diuretic, stimulant, The seeds are valied for the volatile oil present in the antispasmodic, deodorant, and effective against kapha seeds. Seed analysis report 6% mucilage, 11.1 % and vata, intestinal complaints, stomatitis; and diseases moisture, 31.5 % crude