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Summer 2018 BusinessBBSRC is part of UK Research and Innovation INSIDE The quest for Frontier Bioscience AI and machine learning Innovator of the Year 2018 Omega-3 Women in science and innovation Camelina: the quest to find a sustainable source of fish oils. Page 10 About BBSRC-UKRI BBSRC is part of UK Our aim is to further scientific knowledge to meet major challenges, including food to promote economic growth, wealth and security, green energy and healthier, Research and Innovation job creation, and to improve quality of life longer lives. Our investments underpin and invests in world-class in the UK and beyond. important UK economic sectors, such as farming, food, industrial biotechnology bioscience research and Funded by Government, BBSRC invested and pharmaceuticals. training on behalf of the £498M in world-class bioscience in UK public. 2016-2017. We support research and Further details about BBSRC, our training in universities and strategically science and our impact can be found funded institutes. BBSRC research and at www.bbsrc.ukri.org the people we fund are helping society Strategically funded institutes Babraham Institute The Pirbright Institute Institute for Biological, The Quadram Institute www.babraham.ac.uk www.pirbright.ac.uk Environmental and Rural Studies www.quadram.ac.uk (Aberystwyth University) www.aber.ac.uk/en/ibers John Innes Centre Roslin Institute Rothamsted Research Earlham Institute www.jic.ac.uk (University of Edinburgh) www.rothamsted.ac.uk www.earlham.ac.uk Front cover: Douglas Tocher, Monica Betancor and Jonathan Napier, working on the quest for www.roslin.ac.uk Omega-3. See page 10. About Contacts BBSRC Business Plant health and agriculture [email protected] BBSRC Business is a controlled circulation magazine which is Animal health [email protected] distributed free of charge to Bioenergy [email protected] end users of research and to individuals with an interest Food [email protected] in BBSRC. Human health [email protected] For enquiries about Business contact the communications team: Industrial biotechnology [email protected] BBSRC Polaris House, North Star Avenue, International [email protected] Swindon, SN2 1UH. Tel: 01793 442810 Research technologies [email protected] Email: [email protected] Skills and training [email protected] For regular news about BBSRC and the outcomes and impacts of BBSRC- Innovation and business [email protected] funded research visit www.bbsrc.ukri.org/news 2 BBSRC Business Summer 2018 Introduction My vision for Belfast Queen’s University BBSRC-UKRI Melanie Welham, Executive Chair This is the first edition ofBusiness since I was appointed as Executive Chair of BBSRC within UK Research and Innovation. There is the usual mix of exciting news, developments and features but I would also like to take this opportunity to set out my vision for an exciting future. BBSRC has a key role in providing leadership and support for UK bioscience research and enabling researchers to build on their discoveries through innovation. I want BBSRC to be an intelligent investor in research, supporting and enhancing the excellence of UK bioscience and maximising the generation of new knowledge and opportunities to deliver impact. I see three key elements that will be Melanie recently visited Queen’s University Belfast to deliver the Gender Equality Annual Lecture to staff and fundamental to delivering my vision. First students. Seen here with Dr Michelle McKinley, Professor Pascal McKeown and Professor Karen McCloskey. is for BBSRC to be strategic and forward looking. We will continue to build on strong strategic challenges of the 21st century BBSRC and UK Research and Innovation foundations, developing the talent and – sustainability of resources, of food and – the people who provide the vital linkage infrastructure that are key for a vibrant agriculture and of health. between the bioscience community research ecosystem. We will support and the organisation. I originally joined Second is building strong strategic discovery research and transformative BBSRC on secondment from my academic partnerships. We already partner in many technologies to advance the frontiers appointment at the University of Bath, different geometries, both at a national of knowledge. We will ensure that bringing direct experience of the research and international level. The creation of bioscience contributes to addressing the environment with me. We are now exploring UK Research and Innovation provides the ways in which we can develop closer links opportunity to do this more effectively, with the research base to promote more Sir Mark Walport and Melanie visited the Quadram especially at a cross-Council level, a topic of this type of knowledge exchange. When Institute recently where £40 million research frequently raised with me by members investment was announced. The new investing in the talent to deliver we must of the community. To achieve this it will Quadram Institute. Institute. Quadram state-of-the-art building will open later this year. build on the principles of equality, diversity See more on page 4. be important that BBSRC is an open, and inclusion. collaborative and collegiate organisation – I hope that we already are and under my Finally, I offer my personal reflection that leadership we will continue to build on this. the changes heralded by the creation of UK Research and Innovation offer bioscience Of course to deliver, we will need to an even greater opportunity to develop new continue to invest in people, the third knowledge that can make our world a more element underpinning my vision. Continuing sustainable, secure and prosperous place – to support research careers through and that is an exciting prospect which I’m studentships and fellowships is fundamental looking forward to help make happen. and the recently announced UKRI Future Leaders Fellowships offer an excellent new opportunity across all disciplines. It is also important that we nurture the talent within BBSRC Business Summer 2018 3 Headlines £40m new bioscience and Gene-edited pigs resistant to billion- medicine interface dollar virus Scientists have produced pigs that can Science Minister Sam Gyimah announcing the new investment at the Quadram Institute. resist one of the world’s most costly animal diseases, by changing their genetic code. Scientists and clinicians will gain greater of-the-art £75M building and will be home understanding of the impact of food on health to a new gastrointestinal endoscopy unit, Tests with the virus – Porcine Reproductive thanks to a £40M research investment in the with capacity to conduct at least 40,000 and Respiratory Syndrome (PRRS) Virus – new Quadram Institute. procedures a year, making it one of the found the pigs do not become infected at all. largest in Europe. A clinical research facility The animals show no signs that the change Researchers and clinicians are being brought will further link health and nutrition science in their DNA has had any other impact on together in the Quadram Institute and with clinical research under one roof. their health or wellbeing. will work closely with funding bodies and charities, collaborators and investors to Science Minister Sam Gyimah said: PRRS costs the pig industry around £1.75Bn ensure fundamental science benefits patients, “Researchers funded by BBSRC are making each year in lost revenue in the US and consumers and wider society. a real difference: helping feed the world, Europe. Vaccines have mostly failed to stop keeping us healthier for longer, and making the spread of the virus – which continues to The four-year £40M investment in research the UK a more prosperous place. Ten million evolve rapidly. is being funded by the Biotechnology and Brits alive today are expected to live to 100, Biological Sciences Research Council (BBSRC), The disease causes breathing problems and and this new £75M institute facility will help part of UK Research and Innovation. deaths in young animals and, if pregnant ensure more of us have a healthy, happy old sows become infected, it can cause them to The Quadram Institute, at the Norwich Research age. Our investment in science is a vital part lose their litter. Researchers at the University Park, is set to open later this year in a new state- of our modern Industrial Strategy.” of Edinburgh’s Roslin Institute used gene, editing techniques to remove a small section Harnessing the power of biology – of the gene. Impact Report 2017 The research was co-funded by BBSRC and Genus PLC. BBSRC has published its latest Impact Report highlighting widespread Professor Alan Archibald said: “Gene editing impacts from investments, including impacts on industry, policy making, gives us a powerful tool to help reduce losses and research infrastructure and capacity. in the farming industry while improving World-class bioscience research drives the UK’s growing bioeconomy the health and welfare of the animals and lies at the heart of key areas of social policy. BBSRC is central themselves.” to sustaining the UK bioeconomy by providing the knowledge and Jef Grainger, Associate Director of BBSRC skills required to drive innovation and capture its benefits and every Science Strategy, said: “This is an exciting year BBSRC invests more than £450M in research, training, and result that demonstrates the potential capabilities. Read more about the impact of BBSRC investment for genome editing to enable significant across the UK and beyond. improvements to be made in the health and http://bit.ly/BBSRCimpact welfare of farmed animals.” 4 BBSRC Business Summer 2018 Headlines Healthy soil lifts animal weight Managing soil by well-designed grazing is The study by Rothamsted Research Farm Platform (NWFP) in Devon, who led the key to an animal’s growth and wellbeing evaluated how efficiently nutrients are used study. according to new research linking soil health, on a livestock farm, on a field-by-field basis The majority of livestock farms in the UK pasture value and sustainable production.
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