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BMJ Open: first published as 10.1136/bmjopen-2019-033985 on 5 May 2020. Downloaded from BMJ Open is committed to open peer review. As part of this commitment we make the peer review history of every article we publish publicly available. When an article is published we post the peer reviewers’ comments and the authors’ responses online. We also post the versions of the paper that were used during peer review. These are the versions that the peer review comments apply to. The versions of the paper that follow are the versions that were submitted during the peer review process. They are not the versions of record or the final published versions. They should not be cited or distributed as the published version of this manuscript. BMJ Open is an open access journal and the full, final, typeset and author-corrected version of record of the manuscript is available on our site with no access controls, subscription charges or pay-per-view fees (http://bmjopen.bmj.com). 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Downloaded from Demographic and health characteristics of Magude district, Southern Mozambique Journal: BMJ Open ManuscriptFor ID peerbmjopen-2019-033985 review only Article Type: Original research Date Submitted by the 04-Sep-2019 Author: Complete List of Authors: Galatas, Beatriz; Instituto de Salud Global Barcelona, Malaria Elimination Initiative; Centro de Investigacao em Saude de Manhica, ISGLobal Nhacolo, Ariel; Centro de Investigacao em Saude de Manhica Munguambe, Humberto; Centro de Investigacao em Saude de Manhica Marti, Helena; Instituto de Salud Global Barcelona, Malaria Elimination Initiative Jamise, Edgar; Centro de Investigaçao em Saúde de Manhiça Guinovart, Caterina; Barcelona Institute for Global Health Cirera, Laia; Instituto de Salud Global Barcelona, Malaria Elimination Initiative Amone, Felimone; Centro de Investigacao em Saude de Manhica Macete, Eusebio; Centro de Investigação em Saúde de Manhiça Bassat, Quique; BARCELONA INSTITUTE FOR GLOBAL HEALTH Rabinovich, Regina; Instituto de Salud Global Barcelona, Malaria http://bmjopen.bmj.com/ Elimination Initiative Alonso, Pedro; WHO, GMP Aide, Pedro; Manhiça Health Research Centre Saute, Francisco; Centro de Investigação em Saúde de Manhiça Sacoor, Charfudin; Centro de Investigacao em Saude de Manhica, Department of Demography Public health < INFECTIOUS DISEASES, Demography < TROPICAL Keywords: MEDICINE, Magude project, Malaria elimination, Population and health on October 1, 2021 by guest. 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Protected copyright. 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 For peer review only - http://bmjopen.bmj.com/site/about/guidelines.xhtml BMJ Open Page 2 of 40 1 2 3 1 Demographic and health characteristics of Magude district, Southern 4 5 2 Mozambique BMJ Open: first published as 10.1136/bmjopen-2019-033985 on 5 May 2020. Downloaded from 6 7 3 8 4 Authors 9 1, 2 1 1,2 10 5 Beatriz Galatas *¶, Ariel Nhacolo¶ , Helena Martí-Soler , Humberto 11 6 Munguambe1, Edgar Jamise1, Caterina Guinovart2, Laia Cirera1,2, Felimone 12 13 7 Amone1, Eusébio Macete1,3, Quique Bassat1,2,5,6, N. Regina Rabinovich2,7, Pedro 14 8 L. Alonso1,2., Pedro Aide1,4, Francisco Saute1, Charfudin Sacoor1 15 16 9 17 10 Affiliations 18 For peer review only 19 11 1. Centro de Investigação em Saúde da Manhiça (CISM), Manhiça, Mozambique; 20 21 12 2. Barcelona Institute for Global Health (ISGlobal), Hospital Clínic- 22 13 Universitat de Barcelona, Barcelona, Spain. 23 24 14 3. National Directorate of Health, Ministry of Health, Mozambique 25 15 4. National Institute of Health, Ministry of Health, Maputo, Mozambique 26 27 16 5. ICREA, Pg. Lluís Companys 23, 08010 Barcelona, Spain. 28 17 6. Pediatric Infectious Diseases Unit, Pediatrics Department, Hospital Sant 29 30 18 Joan de Déu (University of Barcelona), Barcelona, Spain 31 32 19 7. Harvard T.H. Chan School of Public Health, Boston, MA, USA. 33 34 20 *Corresponding Author 35 36 21 E-mail: [email protected] 37 22 ¶ These authors contributed equally to this work http://bmjopen.bmj.com/ 38 39 23 40 24 Emails of Authors 41 42 25 [email protected] 43 26 [email protected] 44 45 27 [email protected] on October 1, 2021 by guest. Protected copyright. 46 47 28 [email protected] 48 29 [email protected] 49 50 30 [email protected] 51 31 [email protected] 52 53 32 [email protected] 54 33 [email protected] 55 56 34 [email protected] 57 35 [email protected] 58 59 36 [email protected] 60 1 For peer review only - http://bmjopen.bmj.com/site/about/guidelines.xhtml Page 3 of 40 BMJ Open 1 2 3 37 [email protected] 4 5 BMJ Open: first published as 10.1136/bmjopen-2019-033985 on 5 May 2020. Downloaded from 6 7 38 Key words 8 9 39 10 40 Magude district, population, health, malaria control tools, malaria 11 12 41 elimination 13 42 14 15 16 17 43 Word count 18 For peer review only 19 44 5082 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 http://bmjopen.bmj.com/ 38 39 40 41 42 43 44 45 on October 1, 2021 by guest. Protected copyright. 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 2 For peer review only - http://bmjopen.bmj.com/site/about/guidelines.xhtml BMJ Open Page 4 of 40 1 2 3 45 Abstract 4 5 46 (Word count: 289) BMJ Open: first published as 10.1136/bmjopen-2019-033985 on 5 May 2020. Downloaded from 6 7 47 Objectives: A Demographic and Health Platform (DHP) was established in 8 48 Magude in 2015, prior to the deployment of the project’s interventions. 9 10 49 This platform aimed to inform the design, implementation and evaluation of 11 50 a malaria elimination project planned for the district of Magude, through 12 13 51 the identification of households, and population; and the collection of 14 15 52 demographic, health and malaria information. 16 53 Setting: Magude is a rural district of Southern Mozambique which borders 17 18 54 South Africa. It Forhas nine peer rural healthreview facilities only and one referral health 19 55 center with an inpatient ward. 20 21 56 Intervention: A baseline census geolocated and enumerated all the 22 57 households, residents and non-residents, collected demographic and socio- 23 24 58 economic information at the household and individual levels, as well as 25 59 information on the coverage and usage of malaria control tools. Inpatient 26 27 60 and outpatient data were obtained from the district health authorities. The 28 29 61 demographic platform was updated in 2016. 30 62 Results: The baseline census conducted in 2015 reported 48,448 (92.1%) 31 32 63 residents and 4,133 (7.9%) non-residents, and 10,965 households in Magude. 33 64 Magude’s population is predominantly young, half of the population is 34 35 65 illiterate and the main economic activities are agriculture and fishing.