DOCSLIB.ORG

Phytochemical and Pharmacological Profile of Gymnema Sylvestre

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Phytochemical and Pharmacological Profile of Gymnema Sylvestre International Journal of Engineering Technology Science and Research IJETSR www.ijetsr.com ISSN 2394 – 3386 Volume 5, Issue 3 March 2018 Review: Phytochemical and Pharmacological Profile of Gymnema Sylvestre. 1 Shobha Rupanar, 2Shirish Pingale 1. Research Scholarat Baburaoji Gholap College, New Sangavi, Pune & Faculty at Dr. D.Y.Patil School of Engineering, Maharashtra, India. 2Dept. of Chemistry, A. C. S. College Narayangaon, Junnar, Pune, Maharashtra, India Abstract Medicinal plants are the key source for drugs in the Indian medicine system and also in other ancient systems in the world.Nutritional value of medicinal plants has been intensively evaluated for many decades.Gymnema sylvestre, awell- known antidiabetic important medicinal plant, whose therapeutic value has been studied in different systems of traditional medication. The plant used for the management of different disease and ailments of human beings. Along with this G. sylvestre have antidiabetic, antiinflammatory, anticancer, and antioxidant properties. Present review gives information about recent studies done on G.sylvestre& highlights its phytochemical and biological potential. Key words: Gymnema sylvestre, Phytochemical, Pharmacological profile 1.0 INTRODUCTION 1.1Information of Plant Gymnema sylvestre Wild R.Br belongs to family Apocynaceae (Subfamily: Asclepiadaceae), an herbal medicinal plant used in traditional medicine to treat diabetes.In ancient times, Gymnema was known as ‘Gurmar’, which means sugar killer. This plant is used by Indian healers for nearly 2000 years as part of the Ayurvedic traditional system. Forcenturies, Gymnema plant extracts have been used as treatment for diabetes,aas it can lead to serious complications ranging from stroke to blindness. The plant has wide utilityin treatment of both types of diabetes, type I and II. Literature search shows that it not only lowers the level of blood sugar but may help repair damaged cells in pancreas, the gland in which insulin is produced thereby improving production. In addition, Gymnema is reputed to reduce the urge to eat sweets thus it helps to avoid eating sweets. Many individuals have experienced that drinking a cup of tea with a few drops of gymnema extract will make sweet things bitter for at least two hours. Therefore, this herb is useful in controlling diabetes in the existing and prospective patients.It is a valuable medicinal plant used in folk medicine to treat diabetes, obesity, asthma etc. in India for antiquity. Itis also used in the treatment of asthma, eye complaints, inflammations, family planning and snakebite. It also acts as feeding deterrents tocaterpillar, Prodenia eridania. It alsoprevents dental caries caused by Streptococcus mutans and in skin cosmetics [1].The plant is used as therapeutic agents for treatment of several pathogenic caused diseases. 1.2 Botanical description of the plant:The medicinal plant is avaliable throughout India, in dry forests upto 600 m, common throughout the district from January to November. Distributed in Asia, Trophical Africa, Malaysia and Srilanka [1]. (a) Classification Kingdom: Plantae Division: Angiospermae Class: Dicotyledoneae Order: Contortae Family:Apocynaceae 756 Shobha Rupanar, Shirish Pingale International Journal of Engineering Technology Science and Research IJETSR www.ijetsr.com ISSN 2394 – 3386 Volume 5, Issue 3 March 2018 Sub Family: Asclepiadaceae Genus:Gymnema Species:Sylvestre R.Br. Botanical Name: Gymnema Sylvestre R.Br. (b) Botanical synonym: Asclepias geminata Roxb, Periploca sylvestris Retz. (c)Vernacular name:[2], Sanskrit: Meshashringi, Madhunashini, Hindi: Gur-mar, Merasingi, Marathi: Kavali, Kalikardori,Vakundi, Gujrathi: Dhuleti, Mardashingi, Telugu: Podapatri, Tamil: Adigam, Cherukurinja, Kannada: Sannagerasehambu. 1.3 Part used: Leaves, Stem, Root [3]& Fruit [4] 1.4 Botanical Description: Fig. 1 shows a G.sylvestre plant. G. sylvestre is a large &woody climber. Leaves of this plant are opposite, usually elliptic or ovate (1.25– 2.0 inch × 0.5–1.25 inch). Flowers are small, yellow, in umbellate cymes. Follicles are terete, lanceolate, upto 3 inches in length. Fig.1: 2.0PHYTOCONSTITUENTS OF G. SYLVESTRE Gymnema sylvestre is one ofmedicinal plant used in traditional Indian medicine system and studies on this plant were started as early as 1930. It is well known antidiabetic plantcontains several secondary phytochemicals belonging to category alkaloids, terpenoids, tannin, saponin, flavonoid, phenols, anthraquinones, carbohydrates, and glycosides[2].Due to the large range of biological activities, considerable work has been done to isolate and identify chemical constituents of these leaves.Gymnema leaf contains 4 to 10 % of a group of more than 20 saponins glycosides of the olenane-type including gymnemic acids I-XVIII and gymnemasaponins I-V, Some of the gymnemic acids are acylated (Contains an acyl group), while the gymnemasaponins are non acylated. Acylation affects pharmaceutical activity. Dammarane-type saponins and a polypeptide consisting of 35 amino acid residue called gurmarin and other olenane-type saponins (gymnemasins) have also been isolated. 757 Shobha Rupanar, Shirish Pingale International Journal of Engineering Technology Science and Research IJETSR www.ijetsr.com ISSN 2394 – 3386 Volume 5, Issue 3 March 2018 Leaves of G. sylvestre contain triterpene saponins belonging to oleanane and dammarene classes. Oleanane saponins are gymnemic acids and gymnemasaponins, while dammarene saponins are Gymnemoside[5].The group of antidiabetic molecules has been identified as a gymnemicacids after it was successfully isolated and purified fromthe leaves of G. sylvestre [6]. Along with this other plant constituents are flavones, anthraquinones, hentriacontane, pentatriacontane, α and β-chlorophylls, phytin, resins, dquercitol, tartaric acid, formic acid, butyric acid, lupeol, β- amyrin related glycosides and stigmasterol.Leaves of this species produce acidic glycosides,anthraquinones and their derivatives [7]. The essential oil obtained fromleaves of G.sylvestre plant shows antioxidant and antimicrobial activity [8]. The reported bioactive phyto constituents of G.sylvestre are summarized in Table No. Table No. 1 ReportedBioactive Phytoconstituents fromG.Sylvestre Sr. No. Reference Phytoconstituents & Their Biological activity 1 Arun et al (2014) Gymnemic acid Anti-ulcer, anti-stress, anti-allergic, and functional properties [9] 2 Gupta et al (2014) Gymnemic acid Antimicrobial activity [10] 3 Khanna et al (2009) Gymnemagenol Leishmanicidal activity[11] 4 Vediyappan et al (2011) Gymnemic acids Antifungal applications[12] 5 Daisy Pitchai et al (2009) Dihydroxy gymnemic Normoglycemic&Hypolipi triacetate demic activity[13] 6 Wu Xiangyang et al (2008) Polysaccharides Scavenge hydroxyl radicals [14] 7 Zhongyao et al (2008) Conduritol Hypoglycemic activity [15] 8 Khanna et al (2008) Saponins Antimicrobial activity [16] 9 Sarkar, Sudip et al (1995) Triterpenold saponins Hypoglycemic and antihyperglycemic[17] 11 Kurihara et al (1992) Gymnemic acid homologues Sweetness-inhibiting and Gurmarin substances[18] 10 Toshiaki et al (1991) Peptide Suppressive effect on the neural responses[19] 11 Dateo et al (1973) Gymnemic acid, Antisaccharine [20] 12 Kurihara et al (1969) Gymnemic acid A1 and its Antisweet activity [21] derivatives 13 Singh et al (2016) Gymnemic acid, Immunomodulatory property[22] 14 Verma, Nimisha et al (2008) Glycoside Antidiabetic activity[23] 15 Sugihara et al (2000) Gymnemic acid IV Antihyperglycemic effects[24] 16 Tasaki et al (1988) Gymnemic acids Intestinal sugar absorption inhibiting and anticaries activity[25] 17 Rao et al (1974) Triterpenoid saponins Antiviral activity[26] 18 Sinsheimer et al (1968) Gymnemic acids Antiviral activity[27] 19 Maeda et al (1989) Gymnemic acid [28] 758 Shobha Rupanar, Shirish Pingale International Journal of Engineering Technology Science and Research IJETSR www.ijetsr.com ISSN 2394 – 3386 Volume 5, Issue 3 March 2018 20 Rao et al (1970) Gymnemic acids A-D [29] 21 Wang, Ying et al (2004) Gymnemic acid A. [30] 22 Dateo et al (1973) Gymnemic acid A1 [31] 23 Rao et al (1971) Gymnemagenin and [32] Gymnestrogenin 24 Yoshikawa et al (1989) Gymnemic acid V, VI and VII [33] 25 Lu et al (2009) Conduritol A [34] 26 Wei et al (2008) Conduritol a [35] 27 Zhu et al (2008) Triterpenoid saponins [36] 28 Benbassat et al (2006) Triterpenic prosaponin and [37] sapogenin 29 Daisy et al (2007) Gymnemic triacetate [38] 30 Peng, Shu Lin et al (2005) Triterpenic acid [39] 31 Liu et al (2004) Flavonol glycosides [40] 32 Ye et al (2001) 23-hydroxylongispinogenin, [41] Gymnestrogenin and Gymnemanol. 33 Ye et al (2001) Antisweet saponins [42] 34 Murakami et al (1996) Gymnemosides a (I) and b (II), [43] gymnemic acid V 35 Ye et al (2000) Oleanane saponins [44] 36 Sahu et al (1996) Triterpenoid saponins [45] 37 Yoshikawa et al (1993) Gymnemic acids XV-XVIII [46] 38 Miyatake et al (1993) Conduritol A [47] 39 Yoshikawa et al (1991) Gymnemosides I-VII, [48] 40 Yoshikawa, Kazuko(1991) Gymnemasaponins I-V [49] 41 Yoshikawa et al (1989) Gymnemic acid V, VI and VII [50] 42 Stoecklin et al (1969) Glycosides and aglycons [51] 3.0 STUDIES ON PHARMACOLOGICAL ACTIVITY OF GYMNEMA SYLVESTRE 3.1General properties of the Plant: Literature search indicatesGymnema Sylvestre can be used for the following purpose: 1. Normalizes high blood sugar levels (hypoglycemic) 2. May put the brakes on the urge to eat sweets 3. Diuretic 4 Astringent 6. Stomachic 3.2Gymnema sylvestre is known to possess many pharmacological
Load more

Recommended publications
  • FINAL REPORT NAMIBIA BBI SSFA April 2020 Development of Institutional Synergy to Enable Inventorying and Cultivation of Priorit
    P1-33BEL-000177 – Final Report FINAL REPORT NAMIBIA BBI SSFA April 2020 Development of Institutional Synergy to Enable Inventorying and Cultivation of Priority Species for Conservation in the Southern Africa Region: Medicinal Plants in the Apocynaceae Family The overall objective of this Project is to foster long-term cooperation between key and relevant Institutions in Southern Africa on addressing the unsustainable exploitation of medicinal plants in the Region. The initial focus is a group of plants in the Apocynaceae family that recently became popular in northern Namibia. The project endeavours to i) Conduct traditional and molecular-based taxonomic work to clarify the identity and phylogeny of the targeted species, ii) Contribute to an existing public DNA sequence database (e.g. NCBI), iii) Establish propagation initiatives to reduce pressure on the wild resource, and iv) Develop policy to accord the targeted species legal protection in Namibia and other range states. i) and ii) constitute the immediate Project objectives to which this CBD Bio-Bridge Initiative Small-Scale Funding contributes, through six key activities. All six activities were successfully implemented over the period March 2019 – March 2020, as detailed in the following report: 1. Outline in detail the activities implemented during the Project. Activity 1: Collection trip to northern Namibia – Herbarium voucher specimens of the targeted plants and leaf samples for molecular analysis will be collected from various sites in northern Namibia. Feedback: Herbarium plant specimens, leaf samples as well as soil samples were collected from 85 sites across nine Namibian regions in March – April 2019 (see Collection sites 2019 in “Report_BBI Namibia”).
    [Show full text]
  • Review on Gymnema: an Herbal Medicine for Diabetes Management
    REVIEW ON GYMNEMA: AN HERBAL MEDICINE FOR DIABETES MANAGEMENT Vaidya S.* Dr. H.S.Gaur University, Sagar (M.P.) Abstract Diabetes has been recognized by western medicine since the early 1800 s as being one of the most prevalent and controllable conditions affecting a large portion ofthe population. Gymnema Sylvestre, an Ayurvedic herb, came to be known as "destroyer of sugar" because, in ancient times, Ayurvedic physicians observed that chewing a few leaves of Gymnema sylvestre suppressed the taste of sugar. It is used today all over India for controlling blood sugar. Several bioactives has been isolated from that herb for diabetes cure. The present review elaborate the bioactives and some facts and mechanism which make this herb an effective remedy for the same. Introduction Gymnema Sylvestre is a woody, climbing plant of tropical forests of central and southern India and in parts of Africa. Distribution is worldwide and it is recognized in the traditional medicinal literature of many countries including Australia, Japan, and Vietnam. Gymnema has been referred to in some texts as Asclepias geminata, Gymnema melicida, and Periploca sylvestris. Gymnema has played an important role in Ayurvedic medicine for centuries. Its use has been confined primarily to the management of diabetes mellitus and similar hypo/hyperglycemic conditions. Despite the part used being the leaf, another common name of this species is miracle fruit,[1][2][3] which is shared by two other species: Synsepalum dulcificum and Thaumatococcus daniellii [1]. Vernacular name English : Periploca of the woods Hindi : Gudmar Kannada : Kadhasige Malayalam : Cakkarakkolli, Madhunasini Tamil : Sirukurunkay, Sakkaraikkolli Sanskrit : Mesasrngi Telugu : Podapatra Geographical Distribution G.
    [Show full text]
  • Effect of Gymnema Sylvestre R. Br. Leaves Extract on Certain
    Journal of King Saud University – Science (2013) 25, 135–141 King Saud University Journal of King Saud University – Science www.ksu.edu.sa www.sciencedirect.com ORIGINAL ARTICLE Effect of Gymnema sylvestre R. Br. leaves extract on certain physiological parameters of diabetic rats Aziza A.M. El Shafey, Magda M. El-Ezabi, Moshira M.E. Seliem, Hannen H.M. Ouda, Doaa S. Ibrahim * Department of Zoology, Faculty of Science, Benha University, Egypt Received 29 June 2012; accepted 5 November 2012 Available online 16 November 2012 KEYWORDS Abstract Gymnema sylvestre R. Br. (G. sylvestre) belonging to the family Asclepiadaceae, has been Diabetes mellitus; used as a traditional medicine plant in Africa, Australia and Asia especially in India. Streptozotocin; Aim of the study: The present study aimed to clarify the effect of G. sylvestre leaves extract on Gymnema sylvestre; several physiological parameters of diabetic rats. Plasma glucose; Materials and methods: G. sylvestre leaves extract (18 mg/kg body weight) was orally adminis- Plasma insulin; tered for 30 days to normal and streptozotocin (STZ) diabetic rats. Lipid profile; Results: STZ-diabetic rats exhibited a significant increase in plasma glucose, liver function Liver function enzymes; enzymes [alanine aminotransaminase (ALT) and aspartate aminotransaminase (AST)], triglycer- Oxidative stress ides, total cholesterol, LDL-cholesterol malondialdehyde, catalase, reduced glutathione and a sig- nificant decrease in insulin, HDL-cholesterol and erythrocyte superoxide dismutase levels. Treatment diabetic rats with G. sylvestre leaves extract significantly decreased plasma glucose, ALT, AST, triglycerides, total cholesterol, LDL-cholesterol, malondialdehyde and significantly increased insulin, HDL-cholesterol and erythrocyte superoxide dismutase levels compared to untreated diabetic rats.
    [Show full text]
  • Pharmacologyonline 2: 144-157 (2008) Newsletter Potawale Et Al
    Pharmacologyonline 2: 144-157 (2008) Newsletter Potawale et al. GYMNEMA SYLVESTRE: A COMPREHENSIVE REVIEW Potawale S.E.1*, Shinde V.M.2, Libi Anandi 1, Borade S.1, Dhalawat H.1, Deshmukh R.S.3 1. A.I.S.S.M.S. College of Pharmacy, Kennedy Road, Pune-411001. 2. Bharati Vidyapeeth’s Poona College of Pharmacy, Pune-411037 3. Sinhgad College of Pharmacy, Wadgaon, Pune-411041. Summary Gymnema sylvestre R.Br, commonly known as “Gurmar” belonging to the family Asclepiadaceae and the genus Gymnema, native to the tropical forests of southern and central India, is a perennial, woody climbing plant. The main class of chemical constituents isolated from G. sylvestre is Gymnemic acids (a group of triterpenoid saponins) which are responsible for its anti-diabetic action. This herb is being widely used in the treatment of diabetes. Recent studies have shown that this plant is also has antiobesity, hypolipidaemic, antibacterial and anti-inflammatory potentials. This review pretends to contribute to the knowledge of the pharmacology, phytochemistry and pharmacognostical aspects of the plant. Keywords: Gymnema sylvestre, pharmacology, phytochemistry, review *Address for correspondence: Mr. S.E. Potawale Department of Pharmacognosy, A.I.S.S.M.’S College of Pharmacy, Kennedy Road, Pune-411001 Phone: +919881363782, +919270050808 E-mail: [email protected] 144 Pharmacologyonline 2: 144-157 (2008) Newsletter Potawale et al. Introduction The future of medicine is rooted in the past, before chemists undertook to synthesize synthetic silver bullets for all that ails, and before pharmaceutical companies hitched our collective health to what has become for them a multibillion-dollar wagon1.
    [Show full text]
  • C-4 Gem-Dimethylated Oleanes of Gymnema Sylvestre and Their Pharmacological Activities
    Molecules 2013, 18, 14892-14919; doi:10.3390/molecules181214892 OPEN ACCESS molecules ISSN 1420-3049 www.mdpi.com/journal/molecules Review C-4 Gem-Dimethylated Oleanes of Gymnema sylvestre and Their Pharmacological Activities Giovanni Di Fabio 1, Valeria Romanucci 1, Mauro Zarrelli 2, Michele Giordano 2 and Armando Zarrelli 1,* 1 Department of Chemical Sciences, University Federico II, Complesso Universitario Monte S. Angelo, Via Cintia 4, Napoli 80126, Italy; E-Mails: [email protected] (G.D.F.); [email protected] (V.R.) 2 IMCB-Institute of Composite and Biomedical Materials CNR–National Research Council P E Fermi, (Granatello) Portici, Napoli 80055, Italy; E-Mails: [email protected] (M.Z.); [email protected] (M.G.) * Author to whom correspondence should be addressed; E-Mail: [email protected]; Tel.: +39-081-674-472; Fax: +39-081-674-393. Received: 27 September 2013; in revised form: 21 November 2013 / Accepted: 22 November 2013 / Published: 4 December 2013 Abstract: Gymnema sylvestre R. Br., one of the most important medicinal plants of the Asclepiadaceae family, is a herb distributed throughout the World, predominantly in tropical countries. The plant, widely used for the treatment of diabetes and as a diuretic in Indian proprietary medicines, possesses beneficial digestive, anti-inflammatory, hypoglycemic and anti-helmentic effects. Furthermore, it is believed to be useful in the treatment of dyspepsia, constipation, jaundice, hemorrhoids, cardiopathy, asthma, bronchitis and leucoderma. A literature survey revealed that some other notable pharmacological activities of the plant such as anti-obesity, hypolipidemic, antimicrobial, free radical scavenging and anti-inflammatory properties have been proven too.
    [Show full text]
  • Anatomical Studies on the Leaf of Gymnema Sylvestre (Retz.) IJHM 2016; 4(1): 70-72 Received: 20-11-2015 R.Br
    International Journal of Herbal Medicine 2016; 4(1): 70-72 E-ISSN: 2321-2187 P-ISSN: 2394-0514 Anatomical studies on the leaf of Gymnema sylvestre (Retz.) IJHM 2016; 4(1): 70-72 Received: 20-11-2015 R.Br. ex Schult. (Apocynaceae): A magical herbal medicine Accepted: 23-12-2015 for diabetes Debasmita Dutta Pramanick Botanical Survey of India, Headquarter, CGO Complex, Debasmita Dutta Pramanick 3rd MSO Building, Sector-1, Salt Lake City, Kolkata-700064, West Bengal, India. Abstract Gymnema sylvestre (Retz.) R.Br. ex Schult., belongs to the family Apocynaceae, is a potent antidiabetic herb which has a reputation in Indian Proprietary medicine since the time immemorial. The plant is documented as having beneficiary effects in diabetes due to presence of gymnemic acid. In addition, the plant is also reputed in traditional system of medicine for treatment of various ailments. The present paper deals with morphological and anatomical evaluation of Gymnema sylvestre (Retz.) R.Br. ex Schult. along with its traditional uses. Keywords: Gymnema sylvestre (Retz.) R.Br. ex Schult., Morphology, Anatomy, Traditional uses. 1. Introduction Gymnema sylvestre (Retz.) R.Br. ex Schult., commonly known as ‘Gurmar’, belongs to the family Apocynaceae is one of the most important indigenous medicinal plants of India. The use of this plant to cure diabetes mellitus in India is well practiced since the time immemorial. The plant is widely distributed in Asia, Australia and tropical Africa. In India, the plant is found to grow in open tropical rainforests of central and southern states at an altitude of 100- 1000m. It is also reported from Western Ghats area and extending upto some parts of Western and Northern India [1, 2].
    [Show full text]
  • Botanical Medicine
    prohealth QUICK REFERENCE EVIDENCE INFORMED BOTANICAL MEDICINE ,ĞƌďƐ͕ŶƵƚƌŝƟŽŶ͕ŚŽƌŵŽŶĞƐΘŵĞĚŝĐĂƟŽŶƐ ƌ͘DĂƌŝƐĂDĂƌĐŝĂŶŽΘƌ͘EŝŬŝƚĂ͘sŝnjŶŝĂŬ Introduction ............... 1 Botanical Studying Tips ................. iii Plant Harvesting ............................ vi Intro Intro Food is Medicine ........7 3URWHLQIDW¿EHUFDUERK\GUDWHV .... 9 A Vitamins & minerals .......................14 B Actions ....................... 31 C Constituents............... 59 D Pharmacy ................... 73 E Monographs A-Z.... ..... 85 F Appendix .................... 370 G Toxicology, CIs & Safe Dosing .............370 +HUEVLQ3UHJQDQF\ ............................. 376 H +HUEVLQ3HGLDWULFV .............................. 377 I 13/(; ERDUGH[DPKHUEOLVW ............ 378 +HUEVE\)DPLO\ ................................... 379 J +HUE'UXJ1XWULHQW,QWHUDFWLRQV .......... 382 K Medications (drug & use) .....................386 L Index .......................... 403 +HUEVE\ODWLQQDPH ............................. 406 M +HUEVE\FRPPRQQDPH ..................... 407 N Congratulations RQPDNLQJWKHEHVWLQYHVWPHQWRI\RXUOLIH\RXURZQHGXFDWLRQDQG\RXU O FRQWLQXHGVHUYLFHWR\RXUSDWLHQW¶VTXDOLW\RIOLIH7RKHOSVXSSRUW\RXWKLVWH[WZDVFUHDWHG P DVWKHPRVWXSWRGDWHIXQFWLRQDODQGFRVWHIIHFWLYHFOLQLFDOWH[WDYDLODEOH&RXQWOHVVKRXUVRI UHVHDUFK GHVLJQZHUHVSHQWWRGHYHORSWKHFRQWHQW IRUPDW,QIRUPDWLRQVRXUFHVLQFOXGH Q KXQGUHGVRIRULJLQDOSHHUUHYLHZHGUHVHDUFKDUWLFOHVZLWKFXWWLQJHGJHLQIRUPDWLRQ GHFDGHVRI R HYLGHQFHLQIRUPHGEHVWSUDFWLFHV PXOWLGLVFLSOLQDU\FOLQLFDOH[SHULHQFHZLWKDIRFXVRQresults S based medicine. ,QRUGHUWRJHWWKHPRVWFOLQLFDOXWLOLW\IURPWKLVWH[WLWPXVWEHDYDLODEOHDWDOOWLPHVDVVXFK
    [Show full text]
  • Journal of Threatened Taxa
    PLATINUM The Journal of Threatened Taxa (JoTT) is dedicated to building evidence for conservaton globally by publishing peer-reviewed artcles OPEN ACCESS online every month at a reasonably rapid rate at www.threatenedtaxa.org. All artcles published in JoTT are registered under Creatve Commons Atributon 4.0 Internatonal License unless otherwise mentoned. JoTT allows unrestricted use, reproducton, and distributon of artcles in any medium by providing adequate credit to the author(s) and the source of publicaton. Journal of Threatened Taxa Building evidence for conservaton globally www.threatenedtaxa.org ISSN 0974-7907 (Online) | ISSN 0974-7893 (Print) Communication Angiosperm diversity in Bhadrak region of Odisha, India Taranisen Panda, Bikram Kumar Pradhan, Rabindra Kumar Mishra, Srust Dhar Rout & Raj Ballav Mohanty 26 February 2020 | Vol. 12 | No. 3 | Pages: 15326–15354 DOI: 10.11609/jot.4170.12.3.15326-15354 For Focus, Scope, Aims, Policies, and Guidelines visit htps://threatenedtaxa.org/index.php/JoTT/about/editorialPolicies#custom-0 For Artcle Submission Guidelines, visit htps://threatenedtaxa.org/index.php/JoTT/about/submissions#onlineSubmissions For Policies against Scientfc Misconduct, visit htps://threatenedtaxa.org/index.php/JoTT/about/editorialPolicies#custom-2 For reprints, contact <[email protected]> The opinions expressed by the authors do not refect the views of the Journal of Threatened Taxa, Wildlife Informaton Liaison Development Society, Zoo Outreach Organizaton, or any of the partners. The journal, the publisher,
    [Show full text]
  • Gymnema Sylvestre (Miracle Plant)
    Gymnema sylvestre Other names: Gymnema monatum, Periploca sylvestris, Gemnema, Gimnema (plus nog verskillende skryfwyses van hierdie naam), Marsdenia Sylvestris/sylvestre Melicida Gur-Mar, Gurmar, Gurmarbooti Madhunashini Merasingi Sharduvica Vishani en Miracle Plant In Indië, waar hierdie plant algemeen gebruik word in Ayurveda medisyne, dui die plantnaam op die vernietiging van suiker, en dis dan ook wat die plant so besonders maak. Dit lyk nie besonders nie, ‘n mens sien dit eintlik net per toeval raak. Dit rank tot 3 meter hoog in bome of bosse op, lyk donkergroen, het gladde ovaalvormige blare wat na vorentoe na ‘n punt uitloop en klein trossies geel tot roomkleurige bloeisels, van ver skaars sigbaar. ‘n Mens kan amper sê, dit kruip in ‘n ander plant weg. Ek het dit net raakgesien, omdat dit in ‘n droë boom groei, waar nie ander groen kleur teenwoordig is nie. Kenmerkend is ook die lateks-(melk-)vloei as dit beskadig word. Daar is egter inligtingsbronne wat beweer, dat die plantsap helder is. Buitendien beweer sommige bronne, dat die plant baie giftig is, ander sê, dit is by die meeste mense wat Gymnema plantdele vars of in verwerkte vorm opneem, skadeloos. Daar is dus nog nie genoeg navorsing gedoen nie, ten spyte daarvan, dat die plant in Indië algemeen al honderde jare medisinaal gebruik word. In Indië is die plant se naam ‘vernietig suiker’. Mediese gebruike: Dit bevat ‘n bestanddeel, wat in staat is, om die smaakselle wat soet smaak proe tydelik te blok. Dit maak dan nie sin om soet goed in te neem, want jy kan dit nie proe nie.
    [Show full text]
  • In Vitro Evaluation of Antimicrobial and Antioxidant Activities of Olea Europaea Subsp
    In vitro evaluation of antimicrobial and antioxidant activities of Olea Europaea subsp. africana and Euryops brevipapposus used by Cala community folkloric medicine for the management of infections associated with chronic non-communicable diseases Adegborioye Abiodun A Dissertation Submitted in Partial Fulfillment of the Requirements for the Degree of Master of Science (MICROBIOLOGY) At the Department of Biochemistry and Microbiology Supervisor: Prof C.L. Obi Co-supervisor: Dr B.C. Iweriebor 2017 DECLARATION I hereby declare that the dissertation I have submitted to the University of Fort Hare for the degree of Master of Science in Microbiology is my original work, and has not been previously submitted for any degree at this institution or any other university. Signature/date _______________________________ Adegborioye Abiodun Signature/date ______________________________ Prof C.L. Obi (Supervisor) ii DEDICATION I dedicate this dissertation to GOD Almighty for who He is and who He can never be. “Who is he that saith, and it cometh to pass when the Lord commanded it not” Lamentations 3:37 (KJV) iii ACKNOWLEDGEMENT I thank God Almighty for the grace and favour bestowed upon me, without His presence in my life this would not have been accomplished successfully. I would like to recognise and appreciate the financial assistance of the South Africa Medical Research Council (SAMRC) of South Africa without which this research would not have been possible. I am highly grateful for the bursary. I would like to express my sincere gratitude to my supervisor, Prof CL Obi, for the opportunity to be under his supervision. I would like to acknowledge Dr Ben Iweriebor who has been more than a father and a mentor.
    [Show full text]
  • Gymnema Sylvestre : a Miracle Fruit for Diabetes Cure
    Available online at www.ijpab.com ISSN: 2320 – 7051 Int. J. Pure App. Biosci. 2 (6): 318-325 (2014) Review Article INTERNATIONAL JO URNAL OF PURE & APPLIED BIOSCIENCE Gymnema sylvestre : A miracle fruit for Diabetes cure Mohsina Syedy and Krishnendra Singh Nama* Dept. of Life Science, Career Point University, Kota (Rajasthan) *Corresponding Author E-mail: [email protected] ABSTRACT Gymnema sylvestre R.Br. is a perennial shrub found over the tops of woody trees in tropical forest of India. It is a miracle plant having great anti-diabetic potential. Apart from this it has various traditional uses like in the treatment of urinary complaints, stomach problems, piles, chronic cough, breathing troubles, asthma, eye complaints, cardiopathy, constipation, jaundice, and bronchitis. An inspection of literature revealed some extraordinary pharmacological activities of this plant such as anti-obesity, anti- inflammatory, anti-microbial, hypolipidemic and anti-arthritic activity. Gymnema leaves have many bioactive compounds like Gymnemic acid which is responsible for its tremandous activity specialy its blood glucose lowering capacity. The present review is an effort to emphasize the various traditional use as well as pharmacological uses on G. sylvestre. Keywords : Gymnema sylvestre, Gymnemic acid, Hypolipidemic, anti-diabetic potential. INTRODUCTION During the last decade, the changes in life style and junk food habits have resulted in obesity and diabetes in large area of population. For the treatment of such diseases market is flooded with many synthetic anti- diabetic medicines but the long term use of these drugs has resulted in many side effects. So that natural plant based products are gaining importance.
    [Show full text]
  • Medicinal Plants of Trinidad and Tobago: Selection of Antidiabetic Remedies Angelle L
    Florida International University FIU Digital Commons FIU Electronic Theses and Dissertations University Graduate School 7-8-2016 Medicinal Plants of Trinidad and Tobago: Selection of Antidiabetic Remedies Angelle L. Bullard-Roberts Florida International University, [email protected] DOI: 10.25148/etd.FIDC000775 Follow this and additional works at: https://digitalcommons.fiu.edu/etd Part of the Alternative and Complementary Medicine Commons, Biology Commons, Botany Commons, and the Nutritional and Metabolic Diseases Commons Recommended Citation Bullard-Roberts, Angelle L., "Medicinal Plants of Trinidad and Tobago: Selection of Antidiabetic Remedies" (2016). FIU Electronic Theses and Dissertations. 2546. https://digitalcommons.fiu.edu/etd/2546 This work is brought to you for free and open access by the University Graduate School at FIU Digital Commons. It has been accepted for inclusion in FIU Electronic Theses and Dissertations by an authorized administrator of FIU Digital Commons. For more information, please contact [email protected]. FLORIDA INTERNATIONAL UNIVERSITY Miami, Florida MEDICINAL PLANTS OF TRINIDAD AND TOBAGO: SELECTION OF ANTIDIABETIC REMEDIES A dissertation submitted in partial fulfillment of the requirements for the degree of DOCTOR OF PHILOSOPHY in BIOLOGY by Angelle L. Bullard-Roberts 2016 To: Dean Michael R. Heithaus College of Arts, Sciences and Education This dissertation, written by Angelle L. Bullard-Roberts and entitled Medicinal Plants of Trinidad and Tobago: Selection of Antidiabetic Remedies, having been approved in respect to style and intellectual content, is referred to you for judgment. We have read this dissertation and recommend that it be approved. ____________________________________ Suzanne Koptur ____________________________________ Jennifer Richards ____________________________________ J. Martin Quirke ____________________________________ Maria Fadiman ____________________________________ Bradley C.
    [Show full text]