Downloaded from http://bjo.bmj.com/ on April 14, 2016 - Published by group.bmj.com Clinical science Anatomic and visual function outcomes in paediatric idiopathic intracranial hypertension Sidney M Gospe III,1 M Tariq Bhatti,1,2 Mays A El-Dairi1 1Department of ABSTRACT Monitoring of papilledema severity and early Ophthalmology, Duke Background There is a paucity of literature describing detection of optic atrophy in patients with IIH University Medical Center, Durham, North Carolina USA risk factors for vision loss in paediatric idiopathic have been greatly aided by advances in spectral 2Department of Neurology, intracranial hypertension (IIH). We investigate the final domain optical coherence tomography (SD-OCT). Duke University Medical visual function, spectral domain optical coherence This non-invasive imaging modality is now com- Center, Durham, North tomography (SD-OCT) and enhanced depth imaging monly used to measure the thickness of the peripa- Carolina, USA (EDI)-OCT findings in children with papilledema caused pillary RNFL in IIH, glaucoma and other optic 5–7 Correspondence to by IIH. neuropathies. Moreover, the high resolution of Dr Mays A El-Dairi, Methods Medical records of 31 patients with SD-OCT has allowed pathology of specific layers of Department of Ophthalmology, paediatric IIH (age ≤17 years) were retrospectively the retina to be analysed qualitatively and quantita- Duke Eye Center, Duke reviewed. Optic disc photographs on presentation and tively, and we have recently described examples of university, P.O. Box 3802, Durham, NC 27710, USA; automated perimetry, SD-OCT and EDI-OCT imaging on focal atrophy of retinal layers in the macula in
[email protected] final follow-up visit were statistically analysed to identify adult patients with IIH that is distinct from the patient characteristics and anatomic findings associated already-well-described RGC and RNFL changes.8 Received 17 April 2015 with irreversible vision loss.