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Unani Medicine HIPPOCRATIC JOURNAL OF UNANI MEDICINE Volume 10, Number 1, January - March 2015 Hippocratic J. Unani Med. 10(1): 1 - 136, 2015 CENTRAL COUNCIL FOR RESEARCH IN UNANI MEDICINE Ministry of Ayurveda, Yoga & Naturopathy, Unani, Siddha and Homoeopathy (AYUSH) Government of India Hippocratic Journal of Unani Medicine Chief Patron Minister of AYUSH, Government of India Patron Secretary, Ministry of AYUSH, Government of India International Advisory Board Prof. G.N. Qazi, New Delhi, INDIA Prof. Talat Ahmad, New Delhi, INDIA Prof. Ranjit Roy Chaudhury, Delhi, INDIA Hakim Syed Khaleefathullah, Chennai, INDIA Dr. Fabrizio Speziale, Paris, France Dr. Suraiya H. Hussein, Kuala Lumpur, MALAYSIA Mrs. Sadia Rashid, Karachi, PAKISTAN Prof. Allauddin Ahmad, Patna, INDIA Prof. Ikhlas A. Khan, USA Dr. Maarten Bode, Amsterdam, THE NETHERLANDS Prof. Abdul Hannan, Karachi, PAKISTAN Prof. Usmanghani Khan, Karachi, PAKISTAN Prof. Rashid Bhikha, Industria, SOUTH AFRICA Dr. S.S. Handa, Haryana, INDIA Prof. Ram Vishwakarma, Jammu, INDIA Prof. Irfan Ali Khan, Hyderabad, INDIA Editorial Board Prof. Wazahat Husain, Aligarh Prof. V.H. Talib, Dehradun Dr. (Mrs.) Nandini Kumar, New Delhi Prof. K.M.Y. Amin, Aligarh Dr. O.P. Agarawal, Delhi, INDIA Dr. A.B. Khan, Aligarh Prof. Y.K. Gupta, New Delhi Dr. (Mrs.) Neena Khanna, New Delhi Prof. A. Ray, Delhi, INDIA Dr. (Mrs.) Yasmeen Shamsi, New Delhi Dr. S. Asad Pasha, New Delhi Dr. Mohammad Khalid Siddiqui, Faridabad Prof. S. Shakir Jamil, New Dlehi Dr. Ghufran Ahmed, Aligarh Prof. Mansoor Ahmad Siddiqui, Bengaluru Dr. M.A. Waheed, Hyderabad Editor-in-Chief Prof. Rais-ur-Rahman Director General Central Council for Research in Unani Medicine (CCRUM) Associate Editor Dr. Khalid M. Siddiqui, Deputy Director General, CCRUM Assistant Editors Dr. Wasim Ahmed Azmi, Deputy Director, CRIUM, Lucknow Dr. Munawwar Hussain Kazmi, Deputy Director, CRIUM, Hyderabad Dr. Shariq Ali Khan, Research Officer, RRIUM, Aligarh Mr. Aminuddin, Research Officer (Botany), CCRUM Mr. Shamsul Arfin, Research Officer (Chemistry), CCRUM Mr. Mohammad Niyaz Ahmad, Research Officer (Publication), CCRUM Managing Editor Dr. V.K. Singh, Consultant (Botany), CCRUM Editorial Office CENTRAL COUNCIL FOR RESEARCH IN UNANI MEDICINE Ministry of Ayurveda, Yoga & Naturopathy, Unani, Siddha and Homoeopathy (AYUSH), Government of India 61 - 65, Institutional Area, Janakpuri, New Delhi – 110 058, India Telephone: +91-11-28521981, 28525982, 28525983, 28525831/52/62/83/97, 28520501, 28522524 Fax: +91-11-28522965 • Email: [email protected] • Website: www.ccrum.net Annual Subscription: ` 300/- (India) US $ 100/- (Other Countries) Single Issue: ` 150/- (India) US$ 50/- (Other Countries) Payments in respect of subscription may be sent by bank draft marked payable to Director General, CCRUM, New Delhi. On behalf of Central Council for Research in Unani Medicine (CCRUM) published and printed by Prof. Rais-ur-Rehman Director General, CCRUM at CCRUM headquarters, 61-65 Institutional Area (Opposite ‘D’ Block), Janakpuri, New Delhi – 110058 and printed at Rakmo Press Pvt. Ltd., C-59; Okhla Industrial Area (Phase I), New Delhi - 110020 Contents 1. Therapeutic Evaluation of Unani Coded Drug UNIM-104 in Cases of Non-Alcoholic Fatty .................... 1 Liver Disease (NAFLD) – A Preliminary Clinical Trial Hafiz C. Mohammad Aslam, Zaheer Ahmed, Shahida Begum, Aijaz Ahmad, K. Kabiruddin, Shaikh Nikhat, Javed Ali, Abdul Kareem and Syed Jameeluddin 2. Exploration of Mechanism of Antiinflammatory Action of Habbe-Gule-Aakh ............................................. 9 Musarrat Nafees, N.A. Khan, K.M.Y. Amin and Ghufran Ahmad 3. Toxicity Study of Qurs-e-Hudar in Experimental Animals ......................................................................... 15 Mohd. Nadeem, Mohd. Urooj, Habibur Rahman and Shariq Ali Khan 4. Comparative Analytical Study of the Efficacy of Unani Formulations with Reference to Oligospermia 23 M. Anas and M.M.H. Siddiqui 5. Re-designing of the Unani Preparation From Powder Form into Tablet and its Standardization .......... 31 Along with HPLC Profile Aziz ur Rahman and Tajuddin 6. Development of Standard Operative Procedure (SOP) of a Toothpaste Prepared with the .................. 43 Ingredients of Sunun Poste Mughilan Mohammad Rashid, Shariq Shamsi and Roohi Zaman 7. A Review on Phytochemistry, Pharmacological Properties and Biotechnological Studies in.................. 53 Valeriana officinalis L., An Important Medicinal Herb Anwar Shahzad and Taiba Saeed 8. Some Depletive Plants of Kumaon Himalaya Used in Unani Medicine for Treating ............................. 73 Non-Communicable Diseases and Their Conservation Strategies Zaheer Anwar Ali, Sarfraz Ahmad and Shariq Ali Khan 9. Quality Evaluation of Jawarish-e-Ood Kibreet........................................................................................... 85 Rampratap Meena, D. Ramasamy, S. Mageswari, P. Meera Devi Sri, Shamsul Arfin and Aminuddin 10. Standardization of Unani Drug Post-e-Anar (Fruit rind of Punica granatum L.) ..................................... 95 Nazish Siddiqui, M. Masihuzzaman Ansari, Alvia Khan, Mohd. Bilal Tafseer, Saba Viquar and Abdul Haleem 11. A Study on Diversity of Unani Medicinal Plants Used for Non-Communicable Diseases in ............... 105 Southern Western Ghats of Tamil Nadu R. Murugeswaran, K. Venkatesan, Aijaz Ahmed and Aminuddin 12. Pharmacognostical Standardization of Flowers of Althaea officinalis Linn. (Gul Khatami) ................... 117 Nitin Rai, Rampratap Meena, S. Mageswari, Shamsul Arfin, Aminuddin and Rajeev Kr. Sharma 13. Development of Standards of Sapistan (Cordia dichotoma Forst. f.) .................................................... 129 Abdul Haleem, Abdul Latif, Abdur Rauf, Nazish Siddiqui and Sumbul Rehman • Instructions to Contributors Editorial The world-wide interest in traditional medicine has led to renewed efforts to study their medical efficacy and safety on scientific lines. This is particularly true since the dangers and shortcomings of modern medicines have started getting more apparent. Currently there had been many advances in the strategies for discovery and evaluation of drugs, particularly plant based. The input of bio-chemistry to pharmacology followed by clinical trials puts more emphasis on the mode of action of drugs, albeit it becomes clear that the activities of most drugs are not confined to one single mode of action. This has led to generating lot of new researches and there is, therefore, an enormous need for exchange of this vital information for wider use by scientific community across the world engaged in the search of new drugs of plant origin. Although the Unani medicines have been in use for centuries and are known for their therapeutic efficacies, there is a need to scientifically establish their efficacy and safety in order to achieve global acceptance. Organized research work in this system is, therefore, a need of the hour. In this direction, Central Council for Research in Unani Medicine, through its clinical, drug research, literary research, survey & cultivation of medicinal plants programme is contributing significantly for last three decades. Vitiligo, sinusitis, filariasis, eczema, malaria, infective hepatitis, asthma are some of the conditions where Unani therapies have earned recognition after scientific validation. The Council has been publishing the peer reviewed Hippocratic Journal of Unani Medicine (HJUM), mainly to bring out fundamental and applied aspects of Unani Medicine. The journal also publishes recent advances in other related sciences and traditional medicines as well as different streams of medical sciences, which have bearing on validation and scientific interpretation of various concpts and strengths of Unani medicine. In view of an overwhelming response, the journal earlier published twice a year, its periodicity had been changed to quarterly w.e.f. January 2008 to accommodate more articles for quick dissemination of research data among scientific community. The journal has sufficient room for invited articles from luminaries of modern medicine and sciences as well as scholars of Unani medicine. The broad areas being covered include clinical research on single and compound Unani drugs, validation of regimental therapy, Clinical and experimental pharmacological studies, standardization of single and compound drugs, development of standard operating procedures, ethnobotanical studies, experimental studies on medicinal plants and development of agro-techniques thereof, and literary research on classics of Unani medicine. The journal is also open for studies on safety evaluation of Unani and other herbo-mineral drugs, nutraceuticals, cosmotherapeutics, aromatics, oral health, life style disorders, sports medicine etc. and such other newer areas which are the outcome of modern day living. The current issue of this journal provides 13 original and review papers in the areas of clinical research, drug standardization, pharmacology, ethnobotanical surveys and allied disciplines contributed by eminent scholars in their respective fields. It is hoped that data presented will contribute significantly in R&D sector of traditional drugs and prove to be an excellent exposition of current research efforts of scientists in this direction. Council acknowledges the authors for their contributions included in this issue and hope for their continued support in this endeavor. We wish to ensure the readers to bring out the future issues of the journal on time. We at the CCRUM have been constantly
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