KIFAP3 Antibody Cat. No.: 19-403

KIFAP3 Antibody

Immunoprecipitation analysis of 200ug extracts of HeLa cells, using 3 ug KIFAP3 antibody (19-403). Western blot was performed from the immunoprecipitate using KIFAP3 antibody (19-403) at a dilition of 1:1000.

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Rat

Recombinant fusion containing a sequence corresponding to amino acids 1-200 of IMMUNOGEN: human KIFAP3 (NP_055785.2).

TESTED APPLICATIONS: IP, WB

WB: ,1:500 - 1:2000 APPLICATIONS: IP: ,1:50 - 1:100

POSITIVE CONTROL: 1) LO2

2) SH-SY5Y

October 2, 2021 1 https://www.prosci-inc.com/kifap3-antibody-19-403.html 3) Mouse brain

4) Mouse testis

5) Mouse lung

6) Rat lung

PREDICTED MOLECULAR Observed: 110kDa WEIGHT:

Properties

PURIFICATION: Affinity purification

CLONALITY: Polyclonal

ISOTYPE: IgG

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: KIFAP3

FLA3, KAP-1, KAP-3, KAP3, SMAP, Smg-GDS, dJ190I16.1, -associated protein 3, small ALTERNATE NAMES: G protein GDP dissociation stimulator, smg GDS-associated protein

GENE ID: 22920

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G including the Rho and family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This BACKGROUND: protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human - associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene.

October 2, 2021 2 https://www.prosci-inc.com/kifap3-antibody-19-403.html ANTIBODIES FOR RESEARCH USE ONLY.

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October 2, 2021 3 https://www.prosci-inc.com/kifap3-antibody-19-403.html