Orthomolecular Approach to the Treatment of Schizophrenia

Total Page:16

File Type:pdf, Size:1020Kb

Orthomolecular Approach to the Treatment of Schizophrenia .c= DOCUMENT RESUME ED 123 858 EC 090 226 . _AUTHOR Lall, Geeta Rani . TITLE Grthoolecular Approach to- the Treatment of Schizophrenia, Childhood'Psychoses; and Allied Disorders Such as: Hyperactivity, Autism, Hypoglycemia, and Sub Clinical Pellagra. 1 INSTITUTION Andrews Univ., Berrien Sprints, Mich. Depts of Education. PUB DATE -May 76 15p. EDRS.. PRICE MU-n.83 5C-$1.67 Plus Post'age.. - DESCRIPTORS *Emotionally Disturbed; Exceptional Child Research; *Medical Treatment; *Nutrition; *Psychiatry; ' Psychosis; Schizophrenia IDENTIFIERS Orthomolecular Psychiatry ABSTRACT . Pressnted is research' to support the orthomo lecular rather than the psychodynamic approach to treating schizdpkrenia, psychoses, and allied disorders in c41dren. The orthomolecular approach, also known as orthomolecular psychiatry, is reported to t involve the administration ofmegavitamins (following a study to determine biochemical needs), appropriate diet, exercise, psychbtherapy, and other drugs. Advantages of the orthomolecular approach are noted to include better .treatment results; lest expensive and time-consuming treatment; less guilt feelings and alienation of families; removal of much of the stigma and fear ofthe medical pfoblem because of good prognosis; and more objective, accurate, and easily obtained diagnosis. ISB) -***********A******************************************************* . * DocumentS'acquired'by ERIC include many informal unpublished. 'Jic * .materials not available from other sources. EPIC makes ver effort * * to obtain ,,the best copy. available. Neverth4less, items . marginal * * reproducibility are often encountered and this affects the quality * * of the microfiche and hardcopy reproductions ERIC makes available * * via the EPIC Dowlent Reproduction Service (EbRS). EDRS is not * * responsible for the - quality of the original document. Teproductions'.* * supplied by EDRS are the best tiat can be made fiom the original. * ********44*****************************4********4********************** ,-, VI .. 1114, "" D o- --; 1. US DEPARTMENT OF HEALTH EDUCATION &WELFARE NATIONAL INSTITUTE OF EDUCATION .S DOtuMENT HAS BEEN REPRO. DoCED EXACTLY AS RECEIVED FROM THE PERSON OR ORGANIZATION ORIGIN- 4TNO +7 POINTS OF VIEW OR OPINIONS STATED DO NOT NECESSARILY REPPE SEW OFFICIAL NATIONAL INS', TuTE OF. EbuCA,40T. POSITION OR POLICY A. "`",- ". ORTHOMOLECULAR APPROACH TO THE.MAIMItht OF SCHI7bPHRENIA, CHIIDH.00D PSY,: :e AND ALLIED DISORDERS SUCH AS HYPERACTIVITY, =ISM, HYPOGLYCEMr AM SUB CLINICAL PELLAGRA, by ''"=,.e.ta Rani Lall, Ph.D., . S Astant Profes:sor of F.rlyChildhoo4-40 Special' Educcsticti" . rtirk I --?,..:4k, May -1.a.76, ''',t.f@ '-N%''-..,..:.;,.,..s. i v'1.11 . '''....p,i.441 - 2 . ' 5, ; , 4' . , Orthcinoledular Approach , .. 1 CIrthomolecular.Approadh to theTreatment of Schizophrenia, Childhood Psychoses, and AlliedDisorders Such As: ... Hyperactivity, Autisn,Hypoglycemia,' ; -- -and.Sub...Clinical Pellagra, . allied disorders Children afflicted with-childhoodpsychoses and work. suffer markedly in formallearning. Their behavior disorders _ . - learn. Furthermore, their against their naturaltendency and capacity to behavior is often bizarre andmarkedby-intense hyperactivity and learning, emotional; andsocial ritualism. Thesechildren have extreme adjustment- problems. , t ,z causes andcures Much research has beenconducted to determine the of of'these disorders from thepsychologidal and physiological-points prempesideveloped ate 1) thepsychodynamic view. TWo of, the major The psycliodynamic conce concept.and 2) theorthomolecular approach: is criticized as lackingin. scientifV.prol. teition" oriented Kahan (1973) stated thatthe psyChodynamicor occurrences, or .' approach.is based upon thepremise that chile later life, including traumas, cos bring aboutmental disorders Furthermore,,tengion stgain, and unresolvedprdblems can schizophrenia. /1 J theory result in patho gicaldisorder linClu in the"psychodynamic 1 . ,. alienation is the lack of cannunicatio ,family-soca. ty pressures,,. and w 1 Kahan'crinued to pointpoint outthat asthecause of"mebta llness. I asiriOe casefor proof, yet they althoughthes-t -ories donothave . .. , , I ow° f / 1 Orthcnolecular Approach = 2 are usedFs the basis for diagnosis andtreatment bY therapists through- cut the western world. According to many researchers, not only is there klack.of evidence, I .to support the PosYchodynamic,theory, but in reality it is a handiCap in the field of psychiatry. Bindra (1959) stated that the available I research suggests that' the psychodynamic approach has turned out to be a , "wrong lead." Cott (1970) strongly denounced the excluSive use of drugs., or the psychodynamic approach to cure mental illness and other learning diabilities resulting from,it, , Cott, who isa physician, advocated the orthomolecular treatment researched and founded by Abraham Hoffer and Humphry Usmond. He said, I,. My associates and Ihave carried on research on-the molecular i . basis, of mental disease for:15 years. I am increasingly con- vinced that the provision'of the optimuM2oncentrationssof substancesnormally', presentin the body, in addition 4to other therapeutic mbthods, is the best treatment presently avail- . ,able to schizophrenics., Eecauqe..of their pifferentgenetic O constitution,,many-sthitophrenics may need an intake of,vita- t .mtins not provided by a'normal diet in order toAachieve the optimum molecular environment for. their Minds. ' . , The Orthomolecul5r App4ach i, What, then, is the orthatialecular approach in the treatmnt °V i schizophrenia, childhoOd psychoses,,and allied disorders? 4vIn r "ent .., I:4.1. ears, in the school of4psythi try believe that human thougnt _. .. tatterns: emotions, and actions are affected by th&physical condition . - icy L Orth9molecular Approach t 3 of the body and that the nervous system cannotteexpected to Perfoin its many complicated functions without proper chemical balance (Ross, 7.974). 0. Hilshe4Mer -(1972) pointed out an inteiesting consideration ih terms of biochemical imbalance and learning'` disability. He said, Only wheri the child has a normal internal environment can'WL4' / A learb, grovi, and function; otherwie, the biochemical imbalance .makes him unresponsive to practically all .types of learning and or% leads him rapidly into worse behavioral problems. Fulq. education is made incredibly,difficult _without correcti the biological dysfunctioy. / The orthomolecular approach involves theadmiiiistra 5/1 of mega- vitamins (massive -doses of vitamin 114--niacin--and vi C),appro- priate diet, exercise, psychotherapy, and other typesof drugs. * I a thorough study is done to determine thebiochemi needs, and proper doses of megavitamins are prescribed. This trea nt is also known as orthomolecular pgYchiatry. In the.early 1950's; Abraham Hoffer ,and H hxy Oswald brought the,orthomolecular treatment from theory to p tice by giving niacin to , Sensory distor- 4 schizophrenics in the Province'of Saskatch Canada. .0* tions and hillucinationscharacteristic ofshizophrenia may be the\ result of a chemical known as adrenochroMe. This is a naturally occurring chemiCal-that is formed during te oXidation of adrenalin. Intqestingly, during World War II, adrenlin was used in anesthesia. 'Adrgliochrome, found in old; discolored pplies, of adrenalin, proved to , 01 a. ' r" Otthdmolecular Approach - 4 . chemical themselves cause hallucinaons. Hoffer and CSmond took this thoughts, motions, and and 'reported hai.:e experienced distortIonsin They'alSo"theorized 'perceptions lar to schizd'phrenic patients. ' the formation of apenalinand / that, large untsof niacin could reduce the fact that the first adrenoc - What appeared most striking was through the ortho- eight sc phrenic'patients recovered completely reported .as astounding. molecularreatment. These early results were eight'patienis remained well at the A follow%-. p study revealedthat ill end of ,1' years. ! formal%experiments wereconducted by Hoffer and Ormond with therapy and various other . more p.. lents. They used electroconvulsive addition to the'niacin therapy. trea ntS available.ai that time; in experimkis; patibnts receivingniacin, Intertingly enough,*in both relapses than patientswho'receiVed imp ed significantly withfence niacin (Ross, 1974)., othe forms of:treatment with no been Since the early.1950's, theorthomolecular treptment has professionals. ,Cott (1969)main rest ched,by others and-used by many mind,to function properly,%thebrain requires 't ed that' in order for the Mental illness, which iscldsely ules of many differentsubstanoes. [ in 'fated With physical disease, is the'result of low concentrations vitamins: 'Thiamine (B ),Nicotinic Acid of,.. rain of the following 1 . Acid and cotin 'de (B3), Pyridoxine,(B6)',Biotin (B12), Ascorbic evidence to believe that is Acid. Furthermore, there is sufficient , . affected by changes in unlan:)ehaVior and general mental functions, are gamma=aminolputyric acid, he concentration in thebrain of uric acid, ..i Orthomolecular.Approdh t . Q 6 4 these children showed greater appreciation for people about them. The . progress appeared to be directly, proportional to the length of treatment. ., ,3. -1Ounger'dhildren between the ages of three and eight respondqd,better than did older persons (Cott, 1969). Currently, research investigatiOnis.continuing in the importanceof diet in the creation of an optimum molecular environment for the brain. Dr. Vitale and Velez reported on the grillage of Heliconia, Colombia, . population 5,00044tere babies
Recommended publications
  • Eating Well to Prevent Vitamin B12 Deficiency
    www.healthinfo.org.nz Eating well to prevent vitamin B12 deficiency Vitamin B12 helps keep your body's nerve and blood cells healthy. It helps make DNA, the genetic material in your cells. It also helps prevent a type of anaemia that can make you feel tired and weak. Causes of vitamin B12 deficiency Normally, your stomach and intestines digest and absorb vitamin B12 from your food. Vitamin B12 deficiency happens when your stomach and intestines can't absorb the vitamin. This can happen if any of the following apply. ▪ You have pernicious anaemia. This is where your body destroys the cells in your stomach that help you absorb vitamin B12. ▪ You have had surgery to remove part of your stomach or the last part of your small intestine. ▪ You have a digestive disorder such as coeliac disease or Crohn's disease. ▪ You are on certain long-term medications that make it harder for your body to absorb vitamin B12. These medications include antacids, heartburn medicines such as omeprazole and pantoprazole, and metformin. ▪ You are 65 or older. Vitamin B12 deficiency can also happen if you don't eat enough foods with vitamin B12. Most people in New Zealand get plenty of vitamin B12 from food. But some people might not get enough. These people include: ▪ vegans or strict vegetarians ▪ babies who are breastfed by mothers who are vegan or strict vegetarians ▪ people who eat little or no animal foods ▪ older people who have a poor appetite and eat very small meals. Treating vitamin B12 deficiency Vitamin B12 deficiency is diagnosed through a blood test.
    [Show full text]
  • Is There an Ideal Diet to Protect Against Iodine Deficiency?
    nutrients Review Is There an Ideal Diet to Protect against Iodine Deficiency? Iwona Krela-Ka´zmierczak 1,† , Agata Czarnywojtek 2,3,†, Kinga Skoracka 1,* , Anna Maria Rychter 1 , Alicja Ewa Ratajczak 1 , Aleksandra Szymczak-Tomczak 1, Marek Ruchała 2 and Agnieszka Dobrowolska 1 1 Department of Gastroenterology, Dietetics and Internal Diseases, Poznan University of Medical Sciences, Heliodor Swiecicki Hospital, 60-355 Poznan, Poland; [email protected] (I.K.-K.); [email protected] (A.M.R.); [email protected] (A.E.R.); [email protected] (A.S.-T.); [email protected] (A.D.) 2 Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, 60-355 Poznan, Poland; [email protected] (A.C.); [email protected] (M.R.) 3 Department of Pharmacology, Poznan University of Medical Sciences, 60-806 Poznan, Poland * Correspondence: [email protected]; Tel.: +48-665-557-356 or +48-8691-343; Fax: +48-8691-686 † These authors contributed equally to this work. Abstract: Iodine deficiency is a global issue and affects around 2 billion people worldwide, with preg- nant women as a high-risk group. Iodine-deficiency prevention began in the 20th century and started with global salt iodination programmes, which aimed to improve the iodine intake status globally. Although it resulted in the effective eradication of the endemic goitre, it seems that salt iodination did not resolve all the issues. Currently, it is recommended to limit the consumption of salt, which is the main source of iodine, as a preventive measure of non-communicable diseases, such as hypertension or cancer the prevalence of which is increasing.
    [Show full text]
  • Vitamins Minerals Nutrients
    vitamins minerals nutrients Vitamin B12 (Cyanocobalamin) Snapshot Monograph Vitamin B12 Nutrient name(s): (Cyanocobalamin) Vitamin B12 Most Frequent Reported Uses: Cyanocobalamin • Homocysteine regulation Methylcobalamin • Neurological health, including Adenosylcobalamin (Cobamamide) diabetic neuropathy, cognitive Hydroxycobalamin (European) function, vascular dementia, stroke prevention • Anemias, including pernicious and megaloblastic • Sulfite sensitivity Cyanocobalamin Introduction: Vitamin B12 was isolated from liver extract in 1948 and reported to control pernicious anemia. Cobalamin is the generic name of vitamin B12 because it contains the heavy metal cobalt, which gives this water-soluble vitamin its red color. Vitamin B12 is an essential growth factor and plays a role in the metabolism of cells, especially those of the gastrointestinal tract, bone marrow, and nervous tissue. Several different cobalamin compounds exhibit vitamin B12 activity. The most stable form is cyanocobalamin, which contains a cyanide group that is well below toxic levels. To become active in the body, cyanocobalamin must be converted to either methylcobalamin or adenosylcobalamin. Adenosylcobalamin is the primary form of vitamin B12 in the liver. © Copyright 2013, Integrative Health Resources, LLC | www.metaboliccode.com A protein in gastric secretions called intrinsic factor binds to vitamin B12 and facilitates its absorption. Without intrinsic factor, only a small percentage of vitamin B12 is absorbed. Once absorbed, relatively large amounts of vitamin B12 can be stored in the liver. The body actually reabsorbs vitamin B12 in the intestines and returns much of it to the liver, allowing for very little to be excreted from the body. However, when there are problems in the intestines, such as the microflora being imbalanced resulting in gastrointestinal inflammation, then vitamin B12 deficiencies can occur.
    [Show full text]
  • Megavitamin Therapy for Different Cases
    Megavitamin Therapy for Different Cases A. Hoffer, M.D., Ph.D.1 ASCORBIC ACID CURE OF ONE CASE OF TOXIC PSYCHOSIS Recently when I was sorting out my reprints removed as treatment for cancer and then on ascorbic acid I ran across a complete file on received follow-up radiation. The skin over her my first psychotic patient given large doses of breast ulcerated. About five weeks before ascorbic acid alone. I have referred to this case admission she was given testosterone until 10 elsewhere, but have not given any clinical detail. days before. Since this may well be the first case ever treated Because of her severe agitation, depression, in this way, I think it may be useful to report the and paranoid delusions, ECT, the main details. treatment of that day, was indicated. Mrs. V. H., age 47, was referred to the By December 11, 1952, I had persuaded her General Hospital, Munroe Wing, Regina, doctor to allow me to treat her with megadoses because she was delusional, very depressed, and of ascorbic acid, my reasoning being that she threatened to kill herself. She was admitted was probably toxic from her cancer, radiation, December 9, 1952. and the ulceration. He agreed to hold off ECT She was large, obese, masculine in for a few days. appearance with a lot of hair on her face. Her She was started on 1 g of ascorbic acid each complexion was pale and muddy. She suffered hour while awake. If sleeping she was not from perceptual changes, hearing the voice of awakened, but when she did awaken was give her priest, she was confused, delusional, with no 1 g for each hour she had slept.
    [Show full text]
  • Guidelines on Food Fortification with Micronutrients
    GUIDELINES ON FOOD FORTIFICATION FORTIFICATION FOOD ON GUIDELINES Interest in micronutrient malnutrition has increased greatly over the last few MICRONUTRIENTS WITH years. One of the main reasons is the realization that micronutrient malnutrition contributes substantially to the global burden of disease. Furthermore, although micronutrient malnutrition is more frequent and severe in the developing world and among disadvantaged populations, it also represents a public health problem in some industrialized countries. Measures to correct micronutrient deficiencies aim at ensuring consumption of a balanced diet that is adequate in every nutrient. Unfortunately, this is far from being achieved everywhere since it requires universal access to adequate food and appropriate dietary habits. Food fortification has the dual advantage of being able to deliver nutrients to large segments of the population without requiring radical changes in food consumption patterns. Drawing on several recent high quality publications and programme experience on the subject, information on food fortification has been critically analysed and then translated into scientifically sound guidelines for application in the field. The main purpose of these guidelines is to assist countries in the design and implementation of appropriate food fortification programmes. They are intended to be a resource for governments and agencies that are currently implementing or considering food fortification, and a source of information for scientists, technologists and the food industry. The guidelines are written from a nutrition and public health perspective, to provide practical guidance on how food fortification should be implemented, monitored and evaluated. They are primarily intended for nutrition-related public health programme managers, but should also be useful to all those working to control micronutrient malnutrition, including the food industry.
    [Show full text]
  • Vitamins & Supplements
    Lifestyle & Exercise Diet & Prescription Nutrition Drugs Rx Vitamins & Supplements VITAMIN B 12 Functions of B12 In The Body Vitamin B 12, also known as cobalamin, is a member ESSENTIAL FOR DNA SYNTHESIS of the B vitamin family. Vitamin B 12 is often referred to as the “energy vitamin” although as you will see, FACILITATES METABOLISM OF FOLIC ACID performs many other important functions in the body. KEY FACTOR IN METHYLATION WHERE IT HELPS Like other B vitamins, B 12 is water soluble, thus it PREVENT AND TREAT ELEVATED can leave the body quickly, so it should be taken HOMOCYSTEINE WHICH IS A RISK FACTOR twice a day. The average dosage range is between FOR HEART DISEASE AND DEMENTIA 100 and 2000 mcg daily, although higher doses might be needed based on ones plasma levels. INVOLVED IN THE PRODUCTION OF NEUROTRANSMITTERS Vitamin B 12 levels are assessed through a blood test, and a normal reading is between 200 and 900 pg/ml. Levels NEEDED FOR NERVOUS SYSTEM FUNCTION below 200 will generally show signs of B12 deficiency; although in some populations such as the elderly, symptoms HELPS CREATE RED BLOOD CELLS may be noticed with levels between 200 and 500 pg/ml. NEEDED FOR A HEALTHY IMMUNE SYSTEM Since the body does not create vitamin B12 on its own, HELPS SYNTHESIZE PROTEINS it must be consumed from the diet or in supplement form. Food sources include fish, shellfish, meat, liver, REQUIRED FOR DIGESTION, FOOD AND eggs, poultry, dairy products and fortified foods. NUTRIENT ABSORPTION, CARBOHYDRATE AND Low stomach acid and antacid medications can decrease FAT METABOLISM the absorption of B 12 from foods, but not from NEEDED FOR ADRENAL HORMONE supplements, thus supplementation is often a necessary PRODUCTION complement to a healthy diet.
    [Show full text]
  • A Systematic Review and Meta-Analysis of B Vitamin Supplementation on Depressive Symptoms, Anxiety, and Stress: Effects on Healthy and ‘At-Risk’ Individuals
    nutrients Review A Systematic Review and Meta-Analysis of B Vitamin Supplementation on Depressive Symptoms, Anxiety, and Stress: Effects on Healthy and ‘At-Risk’ Individuals Lauren M Young, Andrew Pipingas, David J White , Sarah Gauci and Andrew Scholey * Centre for Human Psychopharmacology, Swinburne University, Melbourne, VIC 3122, Australia; [email protected] (L.M.Y.); [email protected] (A.P.); [email protected] (D.J.W.); [email protected] (S.G.) * Correspondence: [email protected]; Tel.: +61-39214-8932 Received: 8 August 2019; Accepted: 7 September 2019; Published: 16 September 2019 Abstract: A systematic review and meta-analysis was undertaken to examine and quantify the effects of B vitamin supplementation on mood in both healthy and ‘at-risk’ populations. A systematic search identified all available randomised controlled trials (RCTs) of daily supplementation with 3 ≥ B group vitamins with an intervention period of at least four weeks. Random effects models for a standardized mean difference were used to test for overall effect. Heterogeneity was tested using the I2 statistic. Eighteen articles (16 trials, 2015 participants) were included, of which 12 were eligible for meta-analysis. Eleven of the 18 articles reported a positive effect for B vitamins over a placebo for overall mood or a facet of mood. Of the eight studies in ‘at-risk’ cohorts, five found a significant benefit to mood. Regarding individual facets of mood, B vitamin supplementation benefited stress (n = 958, SMD = 0.23, 95% CI = 0.02, 0.45, p = 0.03). A benefit to depressive symptoms did not reach significance (n = 568, SMD = 0.15, 95% CI = 0.01, 0.32, p = 0.07), and there was no effect on anxiety − (n = 562, SMD = 0.03, 95% CI = 0.13, 0.20, p = 0.71).
    [Show full text]
  • Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline 9 Vitamin B12
    Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline http://www.nap.edu/catalog/6015.html 9 Vitamin B12 SUMMARY Vitamin B12 (cobalamin) functions as a coenzyme for a critical methyl transfer reaction that converts homocysteine to methionine and for a separate reaction that converts L-methylmalonyl- coenzyme A (CoA) to succinyl-CoA. The Recommended Dietary Allowance (RDA) for vitamin B12 is based on the amount needed for the maintenance of hematological status and normal serum vitamin B12 values. An assumed absorption of 50 percent is in- cluded in the recommended intake. The RDA for adults is 2.4 µg/ day of vitamin B12. Because 10 to 30 percent of older people may be unable to absorb naturally occurring vitamin B12, it is advisable for those older than 50 years to meet their RDA mainly by consum- ing foods fortified with vitamin B12 or a vitamin B12-containing supplement. Individuals with vitamin B12 deficiency caused by a lack of intrinsic factor require medical treatment. The median intake of vitamin B12 from food in the United States was estimated to be approximately 5 µg/day for men and 3.5 µg/day for women. The ninety-fifth percentile of vitamin B12 intake from both food and supplements was approximately 27 µg/day. In one Canadian province the mean dietary intake was estimated to be approxi- mately 7 µg/day for men and 4 µg/day for women. There is not sufficient scientific evidence to set a Tolerable Upper Intake Level (UL) for vitamin B12 at this time.
    [Show full text]
  • LYSOVIT® (B-Complex+Lysine)
    Lysovit/LPD/PK-02 LYSOVIT® (B-Complex+Lysine) 1. NAME OF THE MEDICINAL PRODUCT LYSOVIT® 2. QUALITATIVE AND QUANTITATIVE COMPOSITION LYSOVIT® Syrup 120 ml Description Each 5 ml contains: Thiamine HCl 4.16 mg Riboflavin USP 1.66 mg Pyridoxine HCl 1 mg Niacinamide USP 18 mg D-Panthenol USP 2.5 mg Cyanocobalamin USP 8.33 mcg Ascorbic Acid USP 75 mg Inositol USP 5 mg Lysine Monohydrochloride USP 33.33 mg 3. PHARMACEUTICAL FORM Syrup 4. CLINICAL PARTICULARS 4.1. THERAPEUTIC INDICATIONS 1. For maintenance of health and to meet the extra energy needs of growing children. 2. Increases appetite and helps in recovery from illnesses. 4.2. POSOLOGY AND METHOD OF ADMINISTRATION Children: 1 teaspoonful daily or as prescribed by the physician Adults: One to two teaspoonsful daily. Shake well before use. Thiamine Benefits: Thiamine is recommended for digestive problems including poor appetite, ulcerative colitis, and ongoing diarrhea. People take thiamine for conditions related to low levels of thiamine (thiamine deficiency syndromes), including beriberi and inflammation of the nerves (neuritis) associated with pellagra or pregnancy.4 1 Lysovit/LPD/PK-02 Thiamine - Daily Recommended Dietary Allowance (RDA): In adults, 1-2 mg of thiamine per day is commonly used. Infants 0-6 months, 0.2 mg Infants 7-12 months, 0.3 mg Children 1-3 years, 0.5 mg Children 4-8 years, 0.6 mg Boys 9-13 years, 0.9 mg Men 14 years and older, 1.2 mg4 Girls 9-13 years, 0.9 mg Women 14-18 years, 1 mg Women over 18 years, 1.1 mg Pregnant women, 1.4 mg Breast-feeding women, 1.5 mg Riboflavin Benefits: Riboflavin had a direct impact on maintenance of good brain function.
    [Show full text]
  • Drug and Medication Classification Schedule
    KENTUCKY HORSE RACING COMMISSION UNIFORM DRUG, MEDICATION, AND SUBSTANCE CLASSIFICATION SCHEDULE KHRC 8-020-1 (11/2018) Class A drugs, medications, and substances are those (1) that have the highest potential to influence performance in the equine athlete, regardless of their approval by the United States Food and Drug Administration, or (2) that lack approval by the United States Food and Drug Administration but have pharmacologic effects similar to certain Class B drugs, medications, or substances that are approved by the United States Food and Drug Administration. Acecarbromal Bolasterone Cimaterol Divalproex Fluanisone Acetophenazine Boldione Citalopram Dixyrazine Fludiazepam Adinazolam Brimondine Cllibucaine Donepezil Flunitrazepam Alcuronium Bromazepam Clobazam Dopamine Fluopromazine Alfentanil Bromfenac Clocapramine Doxacurium Fluoresone Almotriptan Bromisovalum Clomethiazole Doxapram Fluoxetine Alphaprodine Bromocriptine Clomipramine Doxazosin Flupenthixol Alpidem Bromperidol Clonazepam Doxefazepam Flupirtine Alprazolam Brotizolam Clorazepate Doxepin Flurazepam Alprenolol Bufexamac Clormecaine Droperidol Fluspirilene Althesin Bupivacaine Clostebol Duloxetine Flutoprazepam Aminorex Buprenorphine Clothiapine Eletriptan Fluvoxamine Amisulpride Buspirone Clotiazepam Enalapril Formebolone Amitriptyline Bupropion Cloxazolam Enciprazine Fosinopril Amobarbital Butabartital Clozapine Endorphins Furzabol Amoxapine Butacaine Cobratoxin Enkephalins Galantamine Amperozide Butalbital Cocaine Ephedrine Gallamine Amphetamine Butanilicaine Codeine
    [Show full text]
  • Abram Hoffer, MD, Phd Dr
    July 2002 Issue | Abram Hoffer, MD, PhD Dr. Jeffrey Bland - http://jeffreybland.com July 2002 Issue | Abram Hoffer, MD, PhD http://jeffreybland.com/knowledgebase/july-2002-issue-abram-hoffer-md-phd/ DOWNLOAD AUDIO | Welcome to Functional Medicine Update for July 2002. This month I will follow up on a theme from our Ninth International Symposium on Functional Medicine, which we held in May at the Diplomat Hotel and Spa in Fort Lauderdale, Florida. I refer to orthomolecular psychiatry, a topic Dr. Abram Hoffer brought to our attention at the symposium. Together with Dr. Linus Pauling, Dr. Hoffer was an originator of that field. I begin with a quote from an article titled "Orthomolecular Psychiatry," which was published in Science magazine in 1968.1 Dr. Pauling, the principal author of that article, won two Nobel Prizes, one for chemistry and one for peace. "The methods principally used now for treating patients with mental disease are psychotherapy (psychoanalysis and related efforts to provide insight and to decrease environmental stress), chemotherapy (mainly with the use of powerful synthetic drugs, such as chlorpromazine, or powerful natural products from plants, such as reserpine), and convulsive or shock therapy (electroconvulsive therapy, insulin coma therapy, pentylenetetraze! shock therapy). I have reached the conclusion, through arguments summarized in the following paragraphs, that another general method or treatment, which may be called orthomolecular therapy, may be found to be of great value, and may turn out to be the best
    [Show full text]
  • 2021 Equine Prohibited Substances List
    2021 Equine Prohibited Substances List . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. LISTED AS SUBSTANCE ACTIVITY BANNED 1-androsterone Anabolic BANNED 3β-Hydroxy-5α-androstan-17-one Anabolic BANNED 4-chlorometatandienone Anabolic BANNED 5α-Androst-2-ene-17one Anabolic BANNED 5α-Androstane-3α, 17α-diol Anabolic BANNED 5α-Androstane-3α, 17β-diol Anabolic BANNED 5α-Androstane-3β, 17α-diol Anabolic BANNED 5α-Androstane-3β, 17β-diol Anabolic BANNED 5β-Androstane-3α, 17β-diol Anabolic BANNED 7α-Hydroxy-DHEA Anabolic BANNED 7β-Hydroxy-DHEA Anabolic BANNED 7-Keto-DHEA Anabolic CONTROLLED 17-Alpha-Hydroxy Progesterone Hormone FEMALES BANNED 17-Alpha-Hydroxy Progesterone Anabolic MALES BANNED 19-Norandrosterone Anabolic BANNED 19-Noretiocholanolone Anabolic BANNED 20-Hydroxyecdysone Anabolic BANNED Δ1-Testosterone Anabolic BANNED Acebutolol Beta blocker BANNED Acefylline Bronchodilator BANNED Acemetacin Non-steroidal anti-inflammatory drug BANNED Acenocoumarol Anticoagulant CONTROLLED Acepromazine Sedative BANNED Acetanilid Analgesic/antipyretic CONTROLLED Acetazolamide Carbonic Anhydrase Inhibitor BANNED Acetohexamide Pancreatic stimulant CONTROLLED Acetominophen (Paracetamol) Analgesic BANNED Acetophenazine Antipsychotic BANNED Acetophenetidin (Phenacetin) Analgesic BANNED Acetylmorphine Narcotic BANNED Adinazolam Anxiolytic BANNED Adiphenine Antispasmodic BANNED Adrafinil Stimulant 1 December 2020, Lausanne, Switzerland 2021 Equine Prohibited Substances List . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s).
    [Show full text]