Benzodiazepines Addiction & Treatment

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Benzodiazepines Addiction & Treatment Benzodiazepines are often used therapeutically to produce sedation, induce sleep, relieve anxiety and muscle spasms, and to prevent seizures. Benzodiazepines act as hypnotics in high doses, anxiolytics in moderate doses, and sedatives in low doses. Benzodiazepines effect the central nervous system functions and are classified as depressants. They are more commonly referred to as “benzos” or “benzies” and are ingestible in pill form or injected. Benzodiazepines can be found in many medications, including, but not limited to: Xanax (alprazolam), Valium (diazepam), Librium (chlordiazepoxide), Tranxene (clorazepate), Paxipam (Halazepam), Centrax (prazepam), Klonopin/Clonopin (Clonazepam), Serax (oxazepam), Restoril (temazepam), ProSom (estazolam), Dalmane (flurazepam) *Rohypnol (Flunitrazepam) is a benzodiazepine not manufactured or legally marketed in the United States; however it is often smuggled in by traffickers. This drug is often referred to as a “roofie” and is known as both a “party drug” and a “date rape” drug. It often is found to be popular among younger users. Effects of Benzodiazepines Benzodiazepine use can lead to amnesia, hostility, irritability, vivid or disturbing dreams, as well as tolerance and physical dependence. Use with alcohol or another depressant can lead to death, and often benzodiazepine abuse is particularly high among heroin and cocaine abusers. Lasting/Long-Term Effects Benzodiazepines target the emotional response system (limbic) of the brain, rather than the entire central nervous system. This leads to fewer long term effects than other drugs; however continued use can lead to physical and psychological dependence as well as addiction. Due to a tolerance developed to benzodiazepines, users must increase their doses in order to achieve the desired effects. Over an extended period of time, users find themselves unable to sleep without the aid of benzodiazepines. .

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Understanding Benzodiazephine Use, Abuse, and Detection
Siemens Healthcare Diagnostics, the leading clinical diagnostics company, is committed to providing clinicians with the vital information they need for the accurate diagnosis, treatment and monitoring of patients. Our comprehensive portfolio of performance-driven systems, unmatched menu offering and IT solutions, in conjunction with highly responsive service, is designed to streamline workflow, enhance operational efficiency and support improved patient care. Syva, EMIT, EMIT II, EMIT d.a.u., and all associated marks are trademarks of General Siemens Healthcare Diagnostics Inc. All Drugs other trademarks and brands are the Global Division property of their respective owners. of Abuse Siemens Healthcare Product availability may vary from Diagnostics Inc. country to country and is subject 1717 Deerfield Road to varying regulatory requirements. Deerfield, IL 60015-0778 Please contact your local USA representative for availability. www.siemens.com/diagnostics Siemens Global Headquarters Global Siemens Healthcare Headquarters Siemens AG Understanding Wittelsbacherplatz 2 Siemens AG 80333 Muenchen Healthcare Sector Germany Henkestrasse 127 Benzodiazephine Use, 91052 Erlangen Germany Abuse, and Detection Telephone: +49 9131 84 - 0 www.siemens.com/healthcare www.usa.siemens.com/diagnostics Answers for life. Order No. A91DX-0701526-UC1-4A00 | Printed in USA | © 2009 Siemens Healthcare Diagnostics Inc. Syva has been R1 R2 a leading developer N and manufacturer of AB R3 X N drugs-of-abuse tests R4 for more than 30 years. R2 C Now part of Siemens Healthcare ® Diagnostics, Syva boasts a long and Benzodiazepines have as their basic chemical structure successful track record in drugs-of-abuse a benzene ring fused to a seven-membered diazepine ring. testing, and leads the industry in the All important benzodiazepines contain a 5-aryl substituent ring (ring C) and a 1,4–diazepine ring.
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