New Heads of Units for EMBL Heidelberg Council
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Spring 2021 Bulletin
Advancing Access to Civil Justice STEPS TOWARD INTERNATIONAL CLIMATE GOVERNANCE Featuring William Nordhaus, Pinelopi Goldberg, and Scott Barrett HONORING WILLIAM LABOV, RUTH LEHMANN , AND GERTRUD SCHÜPBACH SPRING 2021 SELECT UPCOMING VIRTUAL EVENTS May 6 A Conversation with Architect 27 Reflections on a Full, Consequential, Jeanne Gang and Lucky Life: Science, Leadership, Featuring: Jeanne Gang and Education Featuring: Walter E. Massey (left) in conversation with Don Randel (right) June 14 Lessons Learned from Reckoning with Organizational History Featuring: John J. DeGioia, Brent Leggs, Susan Goldberg, Claudia Rankine, and Ben Vinson 13 Finding a Shared Narrative Hosted by the Library of Congress Featuring: Danielle Allen, winner of the Library’s 2020 Kluge Prize Above: “Our Common Purpose” featuring the Juneteenth flag with one star. Artist: Rodrigo Corral For a full and up-to-date listing of upcoming events, please visit amacad.org/events. SPRING 2021 CONTENTS Flooding beside the Russian River on Westside Road in Healdsburg, Sonoma County, California; February 27, 2019. Features 16 Steps Toward International 38 Honoring Ruth Lehmann and Gertrud Climate Governance Schüpbach with the Francis Amory Prize William Nordhaus, Pinelopi Goldberg, and Scott Barrett Ruth Lehmann and Gertrud Schüpbach 30 Honoring William Labov with the Talcott Parsons Prize William Labov CONTENTS 5 Among the contributors to the Dædalus issue on “Immigration, Nativism & Race” (left to right): Douglas S. Massey (guest editor), Christopher Sebastian Parker, and Cecilia Menjívar Our Work 5 Dædalus Explores Immigration, Nativism & Race in the United States 7 Advancing Civil Justice Access in the 21st Century 7 10 New Reports on the Earnings & Job Outcomes of College Graduates 14 Our Common Purpose in Communities Across the Country Members 53 In Memoriam: Louis W. -
HY Asiakirjapohja
BOARD MEETING 3/2013 E-MAIL MEETING 30 September 2013 MINUTES INSTITUTE FOR MOLECULAR MEDICINE FINLAND FIMM Nordic EMBL Partnership for Molecular Medicine Title: Meeting of the Board of FIMM 3/2013 Time: Monday, 30 September 2013 Place: E-mail Meeting Chair: Vice Rector, Professor Kimmo Kontula, University of Helsinki Attendees: Dean, Professor Risto Renkonen, Faculty of Medicine, University of Helsinki Research Director, Professor Anna-Elina Lehesjoki, Neuroscience Center, University of Helsinki Professor Kimmo Porkka, Institute of Clinical Medicine, Faculty of Medicine, University of Helsinki Chief Research Officer, Professor Lasse Viinikka, HUS Deputy Director General, Professor Juhani Eskola, THL Vice President, Professor, R&D Biotechnology Anu Kaukovirta-Norja, VTT CEO Pekka Mattila, Desentum Oy Director, Professor Eero Vuorio, Biocenter Finland Head of Laboratory Pekka Ellonen, FIMM Technology Centre Presenter: Director, Professor Olli Kallioniemi, FIMM Secretary: Administrative Manager Reetta Niemelä, FIMM 2(5) INSTITUTE FOR MOLECULAR MEDICINE FINLAND FIMM Nordic EMBL Partnership for Molecular Medicine Meeting of the Board of FIMM 3/2013 1 Appointment of the Evaluation Committee for the evaluation of suggested collaboration be- tween FIMM/University of Helsinki and VTT in the field of metabolomics (presenter: Kallioniemi) 2 Dates of the next meetings 3(5) INSTITUTE FOR MOLECULAR MEDICINE FINLAND FIMM Nordic EMBL Partnership for Molecular Medicine 1 Appointment of the Evaluation Committee for the evaluation of suggested collaboration between FIMM/University of Helsinki and VTT in the field of metabolomics (presenter: Kallioniemi) The Directorship of VTT and the University of Helsinki discussed the possible collaboration between FIMM/University of Helsinki and VTT in the field of metabolomics in May 2013. -
Pipsqueak, an Early Acting Member of the Posterior Group of Genes, Affects Vasa Level and Germ Cell-Somatic Cell Interaction in the Developing Egg Chamber
Development 119, 1187-1202 (1993) 1187 Printed in Great Britain © The Company of Biologists Limited 1993 pipsqueak, an early acting member of the posterior group of genes, affects vasa level and germ cell-somatic cell interaction in the developing egg chamber Vivian Siegel*, Thomas A. Jongens, Lily Yeh Jan and Yuh Nung Jan Howard Hughes Medical Institute and Department of Physiology, University of California, San Francisco, CA 94143-0724, USA *Author for correspondence SUMMARY We have identified a new member of the posterior group through vasa; molecular studies indicate that pipsqueak of genes, which we call pipsqueak. We show that affects vasa level in the ovary. We compare vasa and pipsqueak acts after the establishment of the oskar pipsqueak mutant phenotypes in order to determine posterior anchor but before the localization of vasa whether pipsqueak acts solely through vasa, and present protein during oogenesis. Characterization of multiple a model for the role of pipsqueak in posterior pattern alleles at the pipsqueak locus shows that pipsqueak, like formation. vasa, is required for early stages of oogenesis, including but not limited to formation of the egg chamber and pro- gression through Stage 6 of oogenesis. Genetic interac- Key words: Drosophila, oogenesis, posterior pattern formation, tion studies suggest that pipsqueak acts at least partially pipsqueak, vasa INTRODUCTION known collectively as posterior group genes of the grand- childless class, all seem to affect the formation of electron Pattern formation along the anteroposterior axis of the dense particles called polar granules, which are thought to Drosophila melanogaster embryo is initiated prior to fertil- consist of both protein and RNA, and which are localized to ization. -
EMBL in Finland
EMBL in Finland Friday 5 October 2018 Biomedicum 1, Lecture Hall 1 Helsinki PROGRAMME 10:00-10:30 Arrival, coffee and registration 10:30-10:40 Welcome remarks 10:30 Marja Makarow, Director, Biocenter Finland, Helsinki (EMBL Heidelberg, Postdoc, 1981-1983; EMBL Council Advisor, 1999-2008; and President of EMBC, 2004-2007) 10:35 Johanna Myllyharju, Scientific Director, Biocenter Oulu and Professor, University of Oulu (EMBL Council Member, 2016-Present) 10:40-12:20 Session 1: EMBL and EMBO opportunities and resources Chair: Johanna Myllyharju, Scientific Director, Biocenter Oulu and Professor, University of Oulu (EMBL Council Member, 2016-Present) 10:40 Rainer Pepperkok, Head of Core Facilities, Head of Advanced Light Microscopy Core Facility, Team Leader and Senior Scientist, EMBL, Heidelberg “EMBL opportunities and resources” 11:20 Kai Simons, Chief Executive Officer, Lipotype, Dresden “EMBL and me” (EMBL Heidelberg, Head of Cell Biology and Biophysics Unit, 1975-2000; and EMBO Council Member, 2004-2009) 11:40 Tomi Määtä, Predoc, EMBL, Heidelberg “My life as a predoc at EMBL” 11:50 Howy Jacobs, Professor of Molecular Biology, University of Tampere “What you can do for EMBO and EMBO can do for you” 12:10 Discussion 12:20-13:20 Lunch and discussion with the speakers PROGRAMME (continued) 13:20-14:30 Session 2: Collaboration opportunities and research infrastructures Panel chair: Merja Särkioja, Senior Science Adviser, Academy of Finland, Helsinki 13:20 Riitta Maijala, Vice President for Research, Academy of Finland, Helsinki “Finland’s strategy -
EMBO Facts & Figures
excellence in life sciences Reykjavik Helsinki Oslo Stockholm Tallinn EMBO facts & figures & EMBO facts Copenhagen Dublin Amsterdam Berlin Warsaw London Brussels Prague Luxembourg Paris Vienna Bratislava Budapest Bern Ljubljana Zagreb Rome Madrid Ankara Lisbon Athens Jerusalem EMBO facts & figures HIGHLIGHTS CONTACT EMBO & EMBC EMBO Long-Term Fellowships Five Advanced Fellows are selected (page ). Long-Term and Short-Term Fellowships are awarded. The Fellows’ EMBO Young Investigators Meeting is held in Heidelberg in June . EMBO Installation Grants New EMBO Members & EMBO elects new members (page ), selects Young EMBO Women in Science Young Investigators Investigators (page ) and eight Installation Grantees Gerlind Wallon EMBO Scientific Publications (page ). Programme Manager Bernd Pulverer S Maria Leptin Deputy Director Head A EMBO Science Policy Issues report on quotas in academia to assure gender balance. R EMBO Director + + A Conducts workshops on emerging biotechnologies and on H T cognitive genomics. Gives invited talks at US National Academy E IC of Sciences, International Summit on Human Genome Editing, I H 5 D MAN 201 O N Washington, DC.; World Congress on Research Integrity, Rio de A M Janeiro; International Scienti c Advisory Board for the Centre for Eilish Craddock IT 2 015 Mammalian Synthetic Biology, Edinburgh. Personal Assistant to EMBO Fellowships EMBO Scientific Publications EMBO Gold Medal Sarah Teichmann and Ido Amit receive the EMBO Gold the EMBO Director David del Álamo Thomas Lemberger Medal (page ). + Programme Manager Deputy Head EMBO Global Activities India and Singapore sign agreements to become EMBC Associate + + Member States. EMBO Courses & Workshops More than , participants from countries attend 6th scienti c events (page ); participants attend EMBO Laboratory Management Courses (page ); rst online course EMBO Courses & Workshops recorded in collaboration with iBiology. -
The Complex Life of the Complex Life Of
The Complex Life of mRNA EMBO|EMBL Symposium 5–8 October 2016 Heidelberg | Germany EMBL Advanced Training Centre KEYNOTE SPEAKERS Thomas Cech Patrick Cramer Jennifer Doudna University of Colorado Boulder, USA MPI for Biophysical Chemistry, Germany University of California, Berkley, USA ABSTRACT SUBMISSION DEADLINE CONFIRMED SPEAKERS 13 JULY 2016 Maria Barna Rachel Green Shona Murphy Stanford University, USA Johns Hopkins University Sir William Dunn School of Pathology, UK School of Medicine, USA REGISTRATION DEADLINE Simon Bullock Karla Neugebauer 24 AUGUST 2016 MRC Laboratory of Molecular Biology, UK Chuan He Yale University, USA The University of Chicago, USA Emmanuelle Charpentier Uwe Ohler MPI for Infection Biology, Germany Alan Hinnebusch Max Delbrueck Center, Berlin, Germany ORGANISERS NIH, USA Anne Ephrussi Jeffrey Chao Laura Ranum EMBL Heidelberg, Germany Friedrich Miescher Institute for Elisa Izaurralde University of Florida, USA Biomedical Research, Switzerland MPI for Developmental Biology, Germany Nahum Sonenberg Erin Schuman McGill University, Canada Elena Conti Jeff Kieft MPI for Brain Research, Germany MPI of Biochemistry, Germany University of Colorado, USA Joan Steitz Yukihide Tomari Yale University, USA Victoria D'Souza Iain MacRae The University of Tokyo, Japan Harvard University, USA The Scripps Research Institute, USA David Tollervey Jonathan Weissman Wellcome Trust Centre for Cell Biology, UK Caroline Dean James Manley University of California, John Innes Centre, UK Columbia University, USA San Francisco, USA Additional speakers will be Gideon Dreyfuss Christine Mayr Marat Yusupov selected from abstracts. Perelman School of Medicine at the Memorial Sloan Kettering Cancer Institute of Genetics and Molecular University of Pennsylvania, USA Center, USA and Cellular Biology (IGBMC), France CONTACT www.embo-embl-symposia.org [email protected]. -
161104 Press Release Robert Koch Gold Medal 2016 to Kai Simons EN
PRESS RELEASE Robert Koch Gold Medal 2016 to Kai Simons Berlin/Dresden, 4 November 2016: Kai Simons, founding director of the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) and managing director of Lipotype GmbH, receives the Robert Koch Medal in Gold for his lifetime achievements, in particular for his characterization of membrane-forming lipids and the development of the lipid raft concept. The Award Ceremony takes place on Friday, November 4th 2016 at the Berlin-Brandenburg Academy of Sciences and Humanities. Simons has spent his life studying cell membranes, wafer-thin bilayers of fat molecules (“lipids”) that surround each cell of the human body and most cellular compartments. Kai Simons discovered floating nano-assemblies of lipids and proteins in the lipid bilayer of cell membranes that reminded him of the log rafts which Finnish lumberjacks used as platforms drifting downstream – hence the name “lipid rafts”. Simons demonstrated the fascinating properties of these rafts: They are fluid and dynamic, they can appear and disappear. Lipid rafts do not only play a significant role as functional platforms in signal transduction and many other membrane processes, but they are also involved in many diseases such as Alzheimer’s disease and AIDS. “I am overwhelmed!” says laureate Kai Simons. “This award is inspiring and I hope that lipids and lipidomics will continue to stimulate molecular life science research, but ultimately also help to improve health and clinical performance”. Kai Simons started the Cell Biology Program at the European Molecular Biology Laboratory (EMBL) in Heidelberg and moved to Dresden in 2001 to build up the Max Planck Institute of Molecular Cell Biology and Genetics. -
CURRICULUM VITAE KAI SIMONS Name
CURRICULUM VITAE KAI SIMONS Name Simons First Name Kai Date of birth May 24, 1938 Born in Helsinki, Finland Nationality Finnish Civil status married to Carola Simons born Smeds, three children Address: Max-Planck-Institute of Molecular Cell Biology and Genetics Pfotenhauerstr. 108, 01307 Dresden Telephone +49 351 210 2800 Fax +49 351 210 2900 e-mail [email protected] Education 1964 MD, University of Helsinki Research Positions 1965 - 1967 Postdoctoral Research fellow at the Rockefeller University in New York (Prof. A.G. Bearn) 1967 - 1975 Investigator at the Finnish Medical Research Council, University of Helsinki 1971 - 1972 Acting Professor of Biochemistry, Medical Faculty, University of Helsinki 1976 - 1979 Professor, Department of Biochemistry, University of Helsinki 1975 - 2000 Group Leader at the European Molecular Biology Laboratory, Heidelberg 1982 - 1998 Coordinator of the Cell Biology Programme, at the European Molecular Biology Laboratory, Heidelberg 1998 - 2006 Director of the Max-Planck-Institute of Molecular Cell Biology and Genetics, Dresden Present position 1998 – present Group leader at the Max-Planck-Institute of Molecular Cell Biology and Genetics, Dresden Membership in Societies 1975 European Molecular Biology Organisation 1978 Societas Scientarium Fennica 1987 Heidelberg Academy of Sciences 1996 American Academy of Art and Science 1997 Academia Europaea 1997 Foreign Member of the National Academy of Sciences, USA 1998 German Academy of Sciences Leopoldina 2006- Member/Fellow of ScanBalt Academy Honors 1975 Federation -
Lukas A. Huber Biographical Sketch I Studied Medicine at the University
Lukas A. Huber Biographical sketch I studied medicine at the University of Innsbruck. I joined the laboratory of Kai Simons at EMBL in Heidelberg (Germany) as postdoc in epithelial biology until 1994. I then moved to the University of Geneva (Switzerland) and worked in the laboratory of Jean Gruenberg on endocytosis in epithelial cells. In 1996 I started my own laboratory at the I.M.P. in Vienna (Austria) and in 2002 I got appointed as professor and head of the Division of Cell Biology and in 2005 as scientific director of the Biocenter of Innsbruck Medical University (Austria). My research interests have expanded to understanding the spatial and temporal resolution of signaling mechanisms in mammalian cells applying molecular cell biology, mouse genetics and functional proteomics. I initiated and coordinated the FP6 EU program GROWTHSTOP, the Austrian Proteomics Platform of the Austrian Genome Program (GEN-AU), a special research program in Innsbruck entitled “Cell proliferation and Cell Death in Tumors” – SFB021 of the Austrian Science Fund (FWF) and actively participate in several EU programs and also coordinate programs. Since 2009 I am also CSO of the ONCOTYROL center of personalized cancer medicine in Innsbruck, Austria and since 2012 founder and scientific director of the Austrian Drug Screening Institute (ADSI). Curriculum vitae Biozentrum der Medizinischen Universität Innsbruck Sektion für Zellbiologie Innrain 80-82 A-6020 Innsbruck Austria Tel: +43-512-9003-70170 Web: http://biocenter.i-med.ac.at/ http://www.oncotyrol.at/ http://www.adsi.ac.at/ Email [email protected] Date of birth 4 July 1961 Place of birth Vienna, Austria Citizenship Austrian Education 1980 Matura, Humanistisches Gymnasium Paulinum, Schwaz, Austria 1989 MD, Medical School, University of Innsbruck, Austria Career History 1987-1989 M.D. -
Awarded the 2014 Louis-Jeantet Prize for Medicine
PRESS RELEASE Geneva, January 21, 2014 2014 LOUIS-JEANTET PRIZE FOR MEDICINE The 2014 LOUIS-JEANTET PRIZE FOR MEDICINE is awarded to the Italian biochemist Elena Conti, Director of the Department of Structural Cell Biology at the Max-Planck Institute of Biochemistry in Munich (Germany) and to Denis Le Bihan, the French medical doctor, physicist and Director of NeuroSpin, an institute at the French Nuclear and Renewable Energy Commission (CEA) at Saclay near Paris. The LOUIS-JEANTET FOUNDATION grants the sum of CHF 700'000 for each of the two 2014 prizes, of which CHF 625'000 is for the continuation of the prize-winner's work and CHF 75’000 for their personal use. THE PRIZE-WINNERS are conducting fundamental biological research which is expected to be of considerable significance for medicine. ELENA CONTI is awarded the 2014 Louis-Jeantet Prize for Medicine for her important contributions to understanding the mechanisms governing ribonucleic acid (RNA) quality, transport and degradation. In order to function properly, our cells need to degrade macromolecules that are faulty or no longer needed. The biochemist deciphered at the level of atomic resolution how faulty RNAs are recognized and eliminated. Notably, her group deciphered the three-dimensional architecture and molecular mechanisms of the exosome, a multiprotein complex that recognizes and degrades RNAs. The work revealed that several principles of the mechanism of this essential nano-machine are conserved in different forms of life. Elena Conti will use the prize money to conduct further research into the structure and regulation of the exosome. DENIS LE BIHAN is awarded the 2014 Louis-Jeantet Prize for Medicine for the development of a new imaging method that has revolutionized the diagnosis and treatment of strokes. -
PROGRAMME & Book of Abstracts
PROGRAMME & book of abstracts “. MOVING FORWARD TOGETHER” www.EDBC2019Alicante.com ORGANISED BY CONTENTS SPONSORS & COLLABORATORS ORGANIZATION .......................................................................... 4 GENERAL INFORMATION ......................................................... 5 INSTRUCTIONS FOR SPEAKERS AND AUTHORS ................ 8 CONGRESS TIMETABLE ............................................................ 9 SCIENTIFIC PROGRAMME WEDNESDAY 23 .................................................................... 12 THURSDAY 24 ........................................................................ 13 FRIDAY 25 ............................................................................... 16 SATURDAY 26 ........................................................................ 19 POSTER SESSIONS ................................................................... 21 EXHIBITORS AND SPONSORS ................................................ 48 ABSTRACTS ................................................................................ 51 AUTHORS’ INDEX ...................................................................... 263 4 EDBC2019 EDBC2019 5 ORGANIZATION GENERAL INFORMATION ORGANIZING COMMITTEE INVITED SPEAKERS VENUE Ángela Nieto. Alicante Enrique Amaya. Manchester Auditorio de la Diputación de Alicante - ADDA Víctor Borrell. Alicante Detlev Arendt. Heidelberg Paseo Campoamor, s/n Sergio Casas-Tintó. Madrid Laure Bally Cuif. Paris 03010 Alicante, Spain Pilar Cubas. Madrid Fernando Casares. Sevilla www.addaalicante.es -
Ensconsin, a Par-1 Regulated Microtubule Associated Protein, Regulates Kinesin Dependent Transport
Ensconsin, a Par-1 regulated microtubule associated protein, regulates kinesin dependent transport Hsin-Ho Sung 2007 Dissertation submitted to the Combined Faculties for the Natural Sciences and for Mathematics of the Ruperto-Carola University of Heidelberg, Germany for the degree of Doctor of Natural Sciences presented by Master of Science: Hsin-Ho Sung Born in Kaohsiung, Taiwan Oral-examination: 10.07.2007 Ensconsin, a Par-1 regulated microtubule associated protein, regulates kinesin dependent transport Referees: Dr. Anne Ephrussi Dr. Anne Regnier-Vigouroux 僅此獻給 不辭辛苦的母親和在天之靈的父親 Summary Maternal proteins and mRNA contribute to both oocyte and embryo development. I performed a genetic screen to identify genes with maternal function in Drosophila. From this screen, I isolated PB4170, which affects CG14998 (ensconsin). The human homologue of this protein, E-MAP-115/Ensconsin, is known to be a microtubule binding protein that interacts dynamically with microtubules. However, its molecular function is poorly understood. From ensconsin mutant analysis in Drosophila, I have found that this gene is specifically required for microtubule-dependent polarity in the oocyte. My results suggest that Ensconsin does not directly affect the stability or orientation of microtubules, but acts through Kinesin, a plus end directed motor that moves cargos along microtubules. I could also demonstrate that Ensconsin is a target of the Par-1 kinase, which has been shown to be required for the establishment of oocyte polarity in Drosophila. In mammals, the Par-1 homolog MARK destabilises microtubules through phosphorylation of microtubule associated proteins (MAPs).In Drosophila, Par-1 directly affects microtubule stability via unkown MAPs, as the MAPs identified so far do not show any polarity defects in the oocyte.