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Jun05 POSTER 628.Indd The National Cancer Institute at FrederickFrederick What is it? Where is it? Story on page 12. Spring Research Festival JUNE 2005 Nobel Laureate Featured at Spring Research Festival: IN THIS ISSUE J. Michael Bishop Addresses Full House New Faces at NCI-Frederick 3 Dr. J. Michael Bishop, Chancellor MET oncogenes to beta catenin to of the University of California at San HCC and from hepatoblastoma/HCC Poster People Profi le 4 Francisco, who shared the 1989 Nobel to HCC/adenomas. Prize for Physiology or Medicine Exploring the mechanisms of tumor Platinum Publications 6 with former NIH Director Harold E. lymphoma, they have been able to Science Today 9 Varmus, was the keynote speaker at mimic Burkitt’s lymphoma in the May’s Spring Research Festival. mouse model, leading to possible International Women’s Day treatment of this Celebration 10 aggressive disease. Civil War Medicine 11 Using a new generation of mouse models for The Poster Puzzler 12 preclinical testing of therapeutics, based Did You Know? 13 on Dr. Andrei Goga’s Campus Improvement research in Dr. Bishop’s Committee 14 laboratory, they’ve found that treatment for as Student Intern Program 15 little as three weeks with Outreach and Special Purvalanol to inhibit cell Programs 16 cycle kinases in cells overexpressing MYC Frederick Employee Diversity seems to arrest tumors. Team 18 Dr. Bishop emphasized the utility of mouse Off-Site Programs 20 models to provide McKesson BioServices 21 Dr. Bishop lectured on “Mouse insight into genetic contributions to Models for Human Cancer” to a tumorigenesis and facilitate molecular Technology Transfer Branch 22 “full house,” noting that his group exploration of tumorigenesis. had gotten “unexpected lessons from Science in the Cinema showed Race Environment, Health, and Safety mouse models.” His group has done for the Double Helix, exploring the Program 24 extensive research using mouse work of James Watson and Francis Charles River Laboratories 24 models of liver cancer. Crick, with the assistance of Maurice Among these lessons, Dr. Bishop said Wilkins, in defi ning the double helix Data Management Services 25 that potential roles for MET and MYC structure of DNA and earning them SAIC-Frederick, Inc. 26 oncogenes have been authenticated; the 1962 Nobel Prize in Physiology or they’ve determined that the mouse Medicine. After the movie, Dr. Mary Wilson Information Services model is indeed a reasonable facsimile Carrington, a principal investigator in Corporation 27 of human HCC (hepatocellular human genetics with the Laboratory of cancer); and that there are specifi c, Genomic Diversity and director of the Employment Opportunities 28 distinctive pathways leading from the continued on page 2 Spring Research Festival continued from page 1 Basic Science Directorate, discussed the DNA discovery and its impact, and the role of Dr. Rosalind Franklin and other scientists. More information on Dr. Bishop is available at: http://nobelprize.org/redirect/ links_out/prizeawarder .php?from=/ medicine/laureates/1989/presentation- speech.html&object=ki&to=http:// info.ki.se/index_en.html Read the text of Dr. Bishop’s Nobel Lecture and learn more about his research at the e-Nobel site: http://nobelprize.org/medicine/ laureates/1989/index.html The NCI-Frederick Poster 2 June 2005 New Faces at NCI-Frederick NCI-Frederick Welcomes New Staff Melissa McKay Sixty-three people joined our Facility in December 2004, and January and February 2005. Cyril Barinka Charles River Labs welcomes… Lauren Putman Mary Rostkowski Mary Rostkowski NCI-Frederick welcomes… Cyril Barinka Won-Jun Choi Won-Jun Choi Arun Dakshinamurthy WISCO welcomes… Casper Groth Anjali Joshi Chris Miller Ourania Kosti Jeanne Hazzard Junghwa Lim Hong Lou Melissa McKay Daniel Monson SAIC-Frederick, Inc., welcomes… Radek Malik Snehalata Pawar Judy Becerra-Pineros Susan Mertes Arti Santhanam Craig Belldina Daniel Meyers Lauren Putman Manjistha Sengupta Karen Blackburn Tracey Miller Bo Zhu Francis Bonsu Juan Morales-Contreras Liang Cao Claes Ohlen Jeanne Hazzard Keysha Charles Brooke Overcash Brenda Chasteen Mark Parta Kelly Cochran Anil Patri Kathryn Compton Joan Pontius Run Cung Ester Rozenblum Marina Dobrovolskaia Sally Rucker Qian Dong Kimberly Shafer Johnny Epps Donald Shriner Naheed Fatima Poonam Sood Mildred Gapara Stephan Stern Chris Miller Leah Giambarresi Paul Stokely Arun Dakshinamurthy Jennifer Gnuschke Shari Thomas Elizabeth Goddard Jannean Williams Nicole Hoffman Rita Zaledonis Richard Jackson Liubov Zaritskaya Mohamad Jamiluddin Cynthia Kleppinger Vasantha Kumar Casey Matthews The NCI-Frederick Poster 3 June 2005 Poster People Profi le What Do You Do? How long have you worked at NCI- medical judgment and decision- Frederick? In what capacity? making skills, very important in Mary Carol Fleming accident response. I fi rst worked I was hired as an occupational as clinical staff; now, as a senior health nurse in Occupational nurse practitioner, I provide clinical Health Services (OHS) nearly 15 leadership. years ago. What have been the most interesting or What is your specifi c job title exciting changes you’ve seen here? and what are your duties? What training or education do you have The facility has grown so much. for your current job? We now provide services for approximately 2,000 employees. Many Today, my job title is Senior work off-site, so some consultations Nurse Practitioner. I am board- are done by phone. We coordinate certifi ed as an advance practice tests, vaccines, and blood work into registered nurse for adults and one offi ce visit, when possible. The a board-certifi ed occupational OHS staff has expanded; computer health nurse specialist. In software facilitates scheduling addition to my regular duties as and recordkeeping. Obtaining and an experienced nurse practitioner, supplying multiple donor specimens I manage the international travel has become a daily part of the OHS medicine program and the herpes morning routine. I am most excited by simplex virus surveillance the NCI clinical trials being done in program. I continue to provide collaboration with other countries. I Mary Carol Fleming, expertise to the Ergonomics prepare employees medically prior to Senior Nurse Practitioner, Team, and I have a special interest their traveling to Uganda, Mali, China, Occupational Health Services in the prevention and treatment of and elsewhere. cumulative trauma disorders. I completed my master’s degree in How do you participate in the NCI- What do you like best about your work nursing at the University of Maryland, Frederick community—committees, here at NCI-Frederick? Baltimore, for the Adult Nurse other awards, or recognition, etc.? Practitioner in 2000 and also was As a senior nurse practitioner, I work board-certifi ed by the American Board In 2001, I received the SAIC- with many employees one-to-one. I of Nurses as a Certifi ed Registered Frederick, Inc., Scientifi c Achievement enjoy the diversity of the employees, Nurse Practitioner-Adult (CRNP). To award for my participation on the and providing services to protect their maintain certifi cations, actual work Ergonomics Team. I established the health and safety at work is rewarding, experience and continuing education Ergonomic Program and served as the both personally and professionally. credits are required annually. fi rst ergonomic program coordinator, The fi eld of occupational health providing ergonomic training to services bridges the disciplines of How do the demands of your job now employees, supervisors, and engineers. medicine and nursing with program differ from what you did when you fi rst A specifi c work task analysis of management, industrial hygiene, began working here? 13 different job positions was also safety, and risk management. That completed, and an occupational makes my job extremely interesting I function independently as an therapist/ergonomist was on-site for and challenging. Fortunately, occupational health care provider. individual referrals. scientifi c experts on site and medical Although I act under a collaborative experts at the CDC and NIH are agreement with an M.D., my job available for consultation. requires excellent, independent The NCI-Frederick Poster 4 June 2005 Poster People Profi le What Do You Do, Too? headquarters in Wilmington, I Cliff Hubbard came to Frederick. It’s hard to believe that 10 years have passed since that decision, because What do you like best about your work it’s been so enjoyable living in at NCI-Frederick? this area. The people. I work with a group who How do the demands of your job like to do a good job and are proud of now differ from what you did what they do. They also have a sense when you fi rst began working of humor, so when you go home in the here? evening you have a feeling of a job well done and you are laughing. It’s a I came to Frederick as the great feeling. Facility Manager, so basically I am still doing the same job. I How long have you worked at NCI- suppose that when you really like Frederick? In what capacity? what you do on a daily basis, it doesn’t make a difference what I have been at NCI-Frederick for ten your duties are. years now, as the Facility Manager for Charles River Labs. What have been the most interesting or exciting changes What is your specifi c job title, and you’ve seen here? what are your duties? What training Cliff Hubbard, Facility Manager, or education do you have for your I like the way the facility has Charles River Laboratories current job? grown. Buildings have been put up and jobs have been created. There is a I am the Facility Manager, lot of construction now going on and responsible for producing and there is talk of more. shipping high-quality laboratory I am a member of the Employee animals to investigators all over the What are some of the things you’ve Recreation Committee (ERC) and the world.
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