Effector Gene Expression Potential to Th17 Cells by Promoting Microrna

Home , Keratin 19, KIF1A, MYH7B, MYO1E, PCBP3, TLX2

MicroRNA-155 Confers Encephalogenic Potential to Th17 Cells by Promoting Effector Gene Expression

This information is current as Ruozhen Hu, Thomas B. Huffaker, Dominique A. Kagele, of September 26, 2021. Marah C. Runtsch, Erin Bake, Aadel A. Chaudhuri, June L. Round and Ryan M. O'Connell J Immunol published online 17 May 2013 http://www.jimmunol.org/content/early/2013/05/17/jimmun

ol.1300351 Downloaded from

Supplementary http://www.jimmunol.org/content/suppl/2013/05/17/jimmunol.130035 Material 1.DC1 http://www.jimmunol.org/

Why The JI? Submit online.

• Rapid Reviews! 30 days* from submission to initial decision

• No Triage! Every submission reviewed by practicing scientists

• Fast Publication! 4 weeks from acceptance to publication by guest on September 26, 2021

*average

Subscription Information about subscribing to The Journal of Immunology is online at: http://jimmunol.org/subscription Permissions Submit copyright permission requests at: http://www.aai.org/About/Publications/JI/copyright.html Email Alerts Receive free email-alerts when new articles cite this article. Sign up at: http://jimmunol.org/alerts

The Journal of Immunology is published twice each month by The American Association of Immunologists, Inc., 1451 Rockville Pike, Suite 650, Rockville, MD 20852 Copyright © 2013 by The American Association of Immunologists, Inc. All rights reserved. Print ISSN: 0022-1767 Online ISSN: 1550-6606. Published May 17, 2013, doi:10.4049/jimmunol.1300351 The Journal of Immunology

MicroRNA-155 Confers Encephalogenic Potential to Th17 Cells by Promoting Effector Gene Expression

Ruozhen Hu,* Thomas B. Huffaker,* Dominique A. Kagele,* Marah C. Runtsch,* Erin Bake,* Aadel A. Chaudhuri,† June L. Round,* and Ryan M. O’Connell*

Th17 cells are central to the pathogenesis of autoimmune disease, and recently specific noncoding microRNAs have been shown to regulate their development. However, it remains unclear whether microRNAs are also involved in modulating Th17 cell effector functions. Consequently, we examined the role of miR-155 in differentiated Th17 cells during their induction of experimental autoimmune encephalomyelitis. Using adoptive transfer experiments, we found that highly purified, myelin oligodendrocyte glycoprotein Ag-specific Th17 cells lacking miR-155 were defective in their capacity to cause experimental autoimmune encephalomyelitis. Gene expression profiling of purified miR-1552/2IL-17F+ Th17 cells identified a subset of effector genes that are dependent on

miR-155 for their proper expression through a mechanism involving repression of the transcription factor Ets1. Among the genes Downloaded from reduced in the absence of miR-155 was IL-23R, resulting in miR-1552/2 Th17 cells being hyporesponsive to IL-23. Taken together, our study demonstrates a critical role for miR-155 in Th17 cells as they unleash autoimmune inﬂammation and ﬁnds that this occurs through a signaling network involving miR-155, Ets1, and the clinically relevant IL-23–IL-23R pathway. The Journal of Immunology, 2013, 190: 000–000.

utoimmunity occurs when dysregulated, autoreactive im- how miRNAs fit into the known regulatory circuits underlying http://www.jimmunol.org/ mune cells inappropriately respond to self-Ags and cause Th17 cell biology remains an important area of investigation. unwarranted inflammation that is destructive to sophis- miRNAs are small, ssRNA molecules that negatively regulate A + ticated tissue systems (1). Recently, Th17 cells, a subset of CD4 target gene expression posttranscriptionally. Specific miRNAs T cells defined by their expression of IL-17 cytokines, have emerged have been shown to support proper development of immune cells as key drivers of tissue inflammation. Th17 cells promote both the in mammals and have just recently been implicated in autoimmu- onset and persistence of inflammatory responses during autoimmune nity (20, 21). Among the miRNAs expressed in immune cells is disorders including multiple sclerosis, arthritis, psoriasis, lupus, and miR-155, which modulates the development of various inflam- inflammatory bowel disease (2, 3). matory T cell subsets, including Th1, Th17, and regulatory T cells by guest on September 26, 2021 Because of their central roles in driving disease, significant effort (18, 22–26). Demonstrating its importance during inflammation has gone into understanding the genes and pathways that regulate in vivo, we and others have recently shown that miR-1552/2 mice + Th17 cell development. Skewing of naive CD4 T cells toward the are highly resistant to distinct mouse models of autoimmunity, Th17 lineage is driven by the cytokines IL-6 and TGF-b,which including experimental autoimmune encephalomyelitis (EAE)— induce Th17 cell signature genes through such factors as Stat3, a model of human multiple sclerosis, T cell–dependent colitis, and RORgt, Ahr, Batf, and Irf4 (4-12). Furthermore, differentiated collagen-induced arthritis (18, 24, 27). Furthermore, dysregulated Th17 cells must receive additional signals from cytokines such as expression of miR-155 is also observed in mice and people with IL-23 to expand and achieve full inflammatory potential in vivo various types of autoimmune disorders (24, 28–30). Although (13–17). Recently, noncoding microRNAs (miRNAs) have also these reports reveal a prominent, clinically relevant role for miR- been found to regulate Th17 cell development (18, 19). However, 155 during autoimmunity, they have not determined whether this is a consequence of reduced inflammatory T cell numbers or compromised effector cell function. Furthermore, it remains un- *Division of Microbiology and Immunology, Department of Pathology, University of clear how miR-155 functions at the molecular level to instruct † Utah, Salt Lake City, UT, 84112; and Department of Radiation Oncology, Stanford Th17 cell biology. University School of Medicine, Stanford, CA, 94305 In the current study, we have investigated the role of miR-155 Received for publication February 6, 2013. Accepted for publication April 8, 2013. in differentiated Th17 cells. This was accomplished by generat- This work was supported by National Institutes of Health Grant 5R00HL102228-04. ing a novel mouse strain that allows for the isolation and analy- The microarray data presented in this article have been deposited in the National sis of viable, miR-1552/2 IL-17F–expressing CD4+ Tcellsthat Center for Biotechnology Information Gene Expression Omnibus database (http:// www.ncbi.nlm.nih.gov/geo/) under accession number GSE45122. specifically recognize the myelin oligodendrocyte glycoprotein 2/2 Address correspondence and reprint requests to Dr. Ryan M. O’Connell, Division (MOG)35–55 Ag. Our studies find that purified miR-155 Th17 of Microbiology and Immunology, Department of Pathology, University of Utah, 15 cells are extremely defective in causing EAE following adoptive North Medical Drive East, JMRB, Salt Lake City, UT, 84112. E-mail address: ryan. [email protected] transfer when compared with wild-type (Wt) controls. Further- The online version of this article contains supplemental material. more, we demonstrate that miR-155 directly targets the transcription factor Ets1 to regulate a subset of Th17 cell–effector Abbreviations used in this article: EAE, experimental autoimmune encephalomyeli- 2/2 tis; miRNA, microRNA; MOG, myelin oligodendrocyte glycoprotein; qPCR, quan- genes, which includes the IL-23R. Consequently, miR-155 titative real-time PCR; RFP, red fluorescent protein; shRNA, short hairpin RNA; 39- Th17 cells are hyporesponsive to IL-23, revealing a new link UTR, 39-untranslated region; Wt, wild-type. between miR-155 and the highly relevant IL-23–IL-23R pathway Copyright Ó 2013 by The American Association of Immunologists, Inc. 0022-1767/13/$16.00 (31–36).

www.jimmunol.org/cgi/doi/10.4049/jimmunol.1300351 2 miR-155 PROMOTES Th17 CELL FUNCTION

Materials and Methods bus database under accession number GSE45122 (http://www.ncbi.nlm. Mice nih.gov/geo/). All experiments were approved by the University of Utah Institutional ELISAs Animal Care and Use Committee. miR-155+/+, miR-1552/2, Rag12/2, IL- 2 ELISAs to detect expression of IL-17A and IFN-g were performed with 17F red fluorescent protein (RFP)+/ , 2D2 TCR Tg, and combinations of 2 2 cytokine-specific kits (eBioscience), according to the manufacturer’s these mice are all on a C57BL/6 genetic background. miR-155 / mice 2 2 instructions. were crossed with IL-17F RFP+/+ to create miR-155+/ IL-17F RFP+/ +/+ mice, which were crossed further to create both miR-155 and miR- Immunoblotting 1552/2IL-17F RFP+/2 mice. miR-155+/+IL-17F RFP+/+ and miR-1552/2 IL-17F RFP+/+ mice were crossed with Wt 2D2+ to create miR-155+/+IL- Cell pellets were lysed in 8 M urea buffer. Protein extracts were subjected 17F RFP+/22D2+ and miR-1552/2IL-17F RFP+/22D2+ mice, respectively. to gel electrophoresis and transferred onto a nitrocellulose membrane, Genotyping was performed as described previously (22, 37, 38). followed by Ab staining (Ets1 and b-actin; Santa Cruz Biotechnology) and detection as described previously (40). Expression levels were quantified Mouse models of EAE using National Institutes of Health ImageJ software.

EAE was induced in mice as described previously (18). Briefly, MOG35–55 Luciferase reporter assays peptide (BD Biosciences) was emulsified in CFA (100 mg/ml) and injected s.c. into the base of the mouse’s tail. Pertussis toxin was injected i.p. into A region of the 39-untranslated region (39-UTR) of mouse Ets1 containing mice on days 0 and 2. Clinical symptoms of EAE were scored according to the conserved miR-155 binding site was cloned downstream from lucif- the following criteria: 0, no symptoms; 0.5, partially limp tail; 1, com- erase in the pmiReport plasmid. Site-directed mutagenesis was used to pletely limp tail; 1.5, impaired righting reflex; 2, hind-limb paresis; 2.5, disrupt the seed sequence. The forward and reverse primer sequences for hind-limb paralysis; 3, forelimb weakness; 4, complete paralysis; and 5, cloning Ets1 are 59-gtaactagtTACCCGAAACATGGAAGACTC-39 and Downloaded from death. 59-gttaagcttTGCACAGCATGGCTAGGA-39, respectively. The restriction enzyme sites are in lowercase. Luciferase assays were carried out as de- Cell culture and retrovirus infection scribed previously (40). In brief, 293T cells were transfected with com- For Th17 cell skewing, CD4+ splenocytes were isolated by using a CD4+ binations of a miR-155 expression plasmid, a luciferase expression T cell isolation kit (Miltenyi Biotec) per manufacturer’s instruction. The construct with a 39-UTR, and a b-galactosidase expressing plasmid for CD4+ T cells were cultured in RPMI 1640 medium supplemented with normalization. plate-bound anti-CD3e (5 mg/ml), soluble anti-CD28 (2 mg/ml), IL-6 (50 Statistical analysis http://www.jimmunol.org/ ng/ml), and TGF-b (3 ng/ml) (BioLegend) for 72 h. For some experiments, anti–IL-4 (5 mg/ml) and anti–IFN-g Abs (5 mg/ml) were supplemented to Statistical significance was determined by performing a Student two-tailed increase the differentiation of Th17 cells, or IMDM was used instead of t test. A p value , 0.05 was considered significant. For the ingenuity RPMI 1640 medium. For delivery of the control or Ets1 short hairpin RNA transcription factor analysis, the z-score is calculated by the Ingenuity (shRNA)–expressing retrovirus or MIG-IL-23R (Addgene 24066) (39) Pathway Analysis software and represents the confidence that a transcrip- retrovirus, CD4+ T cells were cultured in RPMI 1640 medium with anti- tion factor is activated or repressed based on the consistency between the CD3e and anti-CD28 for 24 h. The next day, cells were spin infected with direction of change of known targets of the transcription regulator from the retrovector-containing medium (2500 rpm, 30˚C) for 90 min and cultured microarray data set and what is expected from literature. in Th17-skewing conditions. The retrovirus was produced by transfecting 293T cells as described previously (40). Infected cells were GFP+, whereas + + IL-17F cells were RFP during FACS analyses. Results by guest on September 26, 2021 Generation and characterization of miR-1552/2 IL-17F RFP Intracellular staining and flow cytometry reporter mice + For analyses of IL-17F–expressing RFP Th17 cells, cells were stained To investigate the role of miR-155 in Th17 cell function and to with fluorophore-conjugated anti-CD4 Abs, followed by FACS analysis circumvent the limitations of using intracellular staining to identify using a BD LSRFortessa machine and FlowJo software. To detect intra- 2 2 cellular expression of IL-17A or IFN-g, splenocytes, lymph nodes, or brain Th17 cells, we developed a mouse strain where miR-155 / Th17 cells (purified with Percoll) were isolated from mice and seeded in 96-well cells are marked with the RFP under the control of the IL-17F plates. Cells were treated with 750 ng/ml ionomycin, 50 ng/ml PMA locus (Fig. 1A). IL-17F RFP reporter mice have been described (Calbiochem), and 1 ml/well of GolgiPlug (BD Biosciences) for 4–5 h at 37˚C. Cells were subsequently surface stained with fluorphore-conjugated previously and shown to faithfully mark Th17 cells both in vitro CD4 and CD3e Abs, followed by permeabilization and fixation. After and in vivo (38). To retain IL-17F function, we created both miR- 2 2 washing, cells were stained with fluorophore-conjugated IL-17A Ab 155+/+ and miR-155 / IL-17F reporter mice that are heterozy- (eBioscience) for 20 min at 4˚C and further analyzed by FACS. In some + + gous for the IL-17F RFP reporter gene. This approach disrupts one experiments, control or Ets1 shRNA-infected GFP RFP cells were FACS allele of the endogenous IL-17F gene and leaves the other intact sorted and stained to detect the expression of IL-17A. For p-STAT3 + to be expressed during Th17 cell development (Fig. 1B). We ob- staining, RFP Th17 cells were sorted after in vitro skewing and replated 2 2 in 96-well plates. Cells were treated with IL-23 and subjected to p-STAT3 served defective expression of IL-17F mRNA in miR-155 / IL- staining (BD Biosciences phosflow mouse anti-Stat3 [pY705]) per man- 17F+/2 RFP reporter CD4+ T cells compared with miR-155+/+ ufacturer’s instruction. control cells under Th17 cell–skewing conditions (Fig. 1B). + Quantitative real-time PCR and microarray Next, we analyzed the capacity of CD4 T cells from both miR-155+/+ and miR-1552/2IL-17F RFP+/2 reporter transgenic To analyze the relative levels of mRNAs encoding BIC, IL-17F, IL-17A, IL-23R, IL-22, Ets1, IL-2 or L32, Sybrgreen-based quantitative real-time mice to express the RFP reporter gene under a variety of different PCR (qPCR) was conducted with the LightCycler 480 PCR system (Roche) Th17 cell–skewing conditions. Impaired Th17 cell differentia- 2 2 2 and gene-specific primers. Primer sequences are available upon request. tion by miR-155 / IL-17F+RFP+/ CD4+ T cells compared with For all experiments, mRNA was normalized to L32. miR-155+/+ controls was observed in all cases, as determined by For the microarray analysis, CD4+ T cells were purified from both 2 2 2 monitoring the formation of RFP-expressing T cells by FACS miR-155+/+ and miR-155 / IL-17F RFP+/ mouse spleens and cultured in vitro with Th17-skewing conditions. CD4+RFP+ and CD4+RFP2 cells (Fig. 1C, 1D). Defective IL-17F RFP expression in the absence of were sorted for both genotypes. Total RNA was isolated using the RNeasy miR-155 also occurred when cells were cultured in IMDM, which kit (Qiagen). Global mRNA levels were assayed using the SurePrint G3 is a medium rich in aromatic amino acids that promotes higher 3 Mouse GE 8 60K Microarray Kit (Agilent), which was carried out levels of Th17 cell differentiation by Wt CD4+ T cells compared by the University of Utah core facility (https://bioserver.hci.utah.edu/ with more conventional RPMI 1640 medium (Fig. 1C, 1D) (41). microarrayweb/ordering.html). The data were analyzed further using + Genesifter and Ingenuity software. All data have been deposited into the We observed very few RFP cells in both groups under neutral, National Center for Biotechnology Information Gene Expression Omni- non-Th17 cell skewing conditions, highlighting the specificity of The Journal of Immunology 3

FIGURE 1. Creation of a miR-1552/2 IL-17F RFP reporter mouse strain. (A) Generation of miR-155+/+ and miR-1552/2 IL-17F RFP reporter mouse strains. Left: Schematic diagram showing the mouse cross. Right: Genotyping results demonstrating completion of the desired mouse strains. (B) Expression of IL-17F mRNA by CD4+ T cells from the indicated genotypes cultured under Th17 cell–skewing conditions was assayed by qPCR over a time course. (C–E)CD4+ T cells were isolated from miR-155+/+ and miR-1552/2CD4+ IL-17F +/2

RFP mice and cultured in vitro under Downloaded from different Th17 cell–skewing conditions. (C) After 72 h, expression of RFP was assayedbyFACS.(D) Average percentage of IL-17F+ cells in different in vitro culture conditions (n =4).(E) ELISA of IL- 17A from in vitro cultured CD4+ T cells.

Error bars represent 6 SEM. *p , 0.05. http://www.jimmunol.org/ by guest on September 26, 2021 this reporter system. Impaired Th17 cell development by the miR- signaling in rheumatoid arthritis as the second most effected pro- 1552/2IL-17F RFP+/2CD4+ T cells, compared with miR-155+/+ cess. Both of these are consistent with a critical role for miR-155 controls, was further confirmed by ELISA. Results demonstrated in Th17 cell biology during autoimmunity. defective concentrations of IL-17A, but not IFN-g, in the culture Many of these pathway differences are represented by the ex- supernatants from miR-1552/2 versus miR-155+/+ IL-17F RFP+/2 pression of specific IL genes, which are either elevated or decreased CD4+ T cells growing under Th17 cell–skewing conditions (Fig. in miR-1552/2IL-17F+ Th17 cells (Fig. 2B). Within this gene 1E). subset, we detected several that have been linked to Th17 cell We also observed the formation of some IL-17F RFP+ Th17 cells biology, including IL-17A, IL-17F, IL-23R, and IL-22, that were in the absence of miR-155. These data demonstrate an important decreased in miR-1552/2IL-17F+ Th17 cells compared with miR- role for miR-155 in Th17 cell development, and validate a novel 155+/+ controls. Alternatively, cytokines representing other Th reagent to be used for experiments with purified and viable miR- lineages, such as IL-4, IL-5, and IL-13, were increased in miR- 155+/+ and miR-1552/2IL-17F+ Th17 cells. 1552/2IL-17F+ Th17 cells (Fig. 2B). qPCR was performed to validate these defects in Th17-related genes expression profiles miR-155 regulates Th17 effector genes in purified observed in miR-1552/2IL-17F+ Th17 cells and among those IL-17F+ Th17 cells assayed were IL-17A, IL-17F, IL-23R, and IL-22 (Fig. 2C, Sup- 2/2 + Although naive miR-155 CD4 T cells are defective in their plemental Fig. 1). We also assessed RORgT mRNA levels and + + output of IL-17–expressing CD4 T cells, a portion of IL-17F found minimal differences between the groups (Fig 2C). These cells are still produced. However, it is not known whether these data demonstrate that miR-155 is not only important for the devel- cells are functional on a per cell basis. To begin answering this opment of IL-17F–expressing cells but also critical for the expres- question, we performed a gene expression analysis on purified sion of Th17 cell effector genes in differentiated, IL-17F–express- +/+ 2/2 + miR-155 and miR-155 IL-17F Th17 cells (Fig. 2A). Global ing Th17 cells. gene expression profiling was performed using a microarray anal- + ysis. Genes differentially regulated by miR-155 in purified IL-17F+ miR-155 directly targets Ets1 in IL-17F Th17 cells Th17 cells were identified, and this subset contained several genes We next sought to identify mRNA targets of miR-155 with rele- involved in T cell–lineage skewing and Th17 cell effector functions vance to Th17 cell biology. To systematically search for potential (Supplemental Table I). miR-155 targets, we further analyzed our microarray data from Fig. Next, we used Ingenuity software to mine our microarray results 2 using an ingenuity transcription factor analysis. Transcription and uncover canonical pathways most impacted by miR-155. This factors predicted to be activated or inhibited in miR-1552/2 approach identified Th cell differentiation as the most significant compared with miR-155+/+IL-17F+ Th17 cells based on differ- biological pathway impacted by miR-155, and altered B and T cell ential gene expression signatures between these two cell groups 4 miR-155 PROMOTES Th17 CELL FUNCTION

FIGURE 2. miR-155 regulates Th17-related genes in puriﬁed IL-17F+ Th17 cells. (A) Schematic diagram of the experimental design. (B) Heat map of the Downloaded from differentially expressed IL genes in miR-155+/+ versus miR-1552/2IL-17F+ Th17 cells (n =2).The colors represent normalized ﬂuorescence values on a log scale. The color key is next to the heat map. (C) Relative expression levels of bic ncRNA and IL- 17A, IL-17F, IL-23R, RORgT, and IL-22 mRNA in FACS-sorted T cells from (B) were assayed by qPCR http://www.jimmunol.org/ (n = 2). Error bars represent 6 SEM. by guest on September 26, 2021

were identiﬁed (Fig. 3A). Because miR-155 inhibits expression direct targeting. We next tested whether miR-155 represses en- of its targets, those transcription factors with a predicted increase dogenous Ets1 in Th17 cells by assaying Ets1 expression in miR- in their levels in miR-1552/2 cells were of interest (Fig. 3A, red 155+/+ and miR-1552/2IL-17F RFP+/2CD4+ T cells under Th17 line). On this list were several factors containing a conserved miR- cell–skewing conditions. Expression of Ets1 was elevated at the 155 binding site in their 39-UTRs, according to Targetscan soft- protein level in miR-1552/2 compared with controls (Fig. 3D). ware, and these include Ets1, AP1 (cFos), C/EBPb, and cMAF. Taken together, these results identify Ets1 as a direct target of Among these, our attention was drawn to Ets1 for several reasons: miR-155 in Th17 cells. 1) Ets1 was the most likely transcription factor to be activated in 2/2 + Ets1 is a functionally relevant target of miR-155 in miR-155 IL-17F Th17 cells according to our analysis (Fig. + 3A); 2) it has a highly conserved bonding site for miR-155 in its IL-17F Th17 cells 39-UTR (Fig. 3B); and 3) it has an established function as an in- Following the identiﬁcation of Ets1 as a direct target of miR-155 hibitor of Th17 cells (42). during Th17 development, we next determined whether reducing To determine whether miR-155 directly targets mouse Ets1, we its levels would impact expression of Th17-related genes in miR- cloned a region of the Ets1 39-UTR containing the conserved miR- 1552/2CD4+ Th17 cells. To accomplish this, we built a retroviral 155 binding site downstream from luciferase and performed lu- vector that expresses an Ets1 shRNA based on a format that we ciferase assays using 293T cells. Results indicated that miR-155 have described previously (43). Using two different Ets1 shRNAs overexpression repressed luciferase in an Ets1 39-UTR–dependent or a control vector, we transduced miR-1552/2CD4+ T cells and as- manner (Fig. 3C). Furthermore, mutation of the miR-155 binding sayed the expression of Ets1 and Th17-related genes under Th17 site in the 39-UTR abolished repression by miR-155, indicating cell-skewing conditions (Fig. 4A). Ets1 protein levels were re- The Journal of Immunology 5

FIGURE 3. miR-155 directly targets Ets1 in Th17 cells. (A) Predicted transcription factors targeted by miR-155 according to an Ingenuity transcription factor analysis of the microarray data from Fig. 2. (B)Conserved miR-155 binding sites in the Ets1 39-UTR, and predicted interaction with the conserved 8-mer seed found within miR-155. (C)Lu- ciferase assays were performed and found that the Ets1 39-UTR has a functional miR- 155 target site. The Picalm 39-UTR and the miR-155 2-mer were included as positive controls, and the TNFR-associated factor 6 (TRAF6) 39-UTR was a negative control. (D) miR-155+/+ or miR-1552/2IL-17F RFP+/2CD4+ T cells were cultured under Th17 skewing conditions. Seventy-two hours later, Ets1 protein levels were assayed by Downloaded from Western blotting (upper), which was quantified for multiple samples (lower)(n = 5). Error bars represent 6 SEM. *p , 0.05. http://www.jimmunol.org/ duced in cells expressing the shRNA cassette when compared with IL-17F+2D2+ Th17 cells (Fig. 5C). Rag12/2 mice receiving the the control vector (Fig. 4B). Ets1 knockdown in miR-1552/2 miR-155+/+IL-17F+2d2+ Th17 cells also had an earlier onset of Th17 cells led to upregulation of several Th17-related genes, in- disease symptoms, which began on day 9 compared with day 14, cluding IL-17A, IL-23R, and IL-22 (Fig. 4B). Of note, Ets1 and a higher disease incidence compared with mice receiving knockdown did not affect IL-17F expression. miR-1552/2IL-17F+2D2+ Th17 cells (Fig. 5C, 5D). We also an- To further define the role of Ets1 in purified Th17 cells, we took alyzed the brains and spleens from both groups for the presence of advantage of our IL-17F reporter system and sorted out RFP+ (IL- transferred IL-17F+ Th17 cells. Consistent with the reduced EAE 17F+) GFP+ (vector+) cells from both miR-155+/+ and miR-1552/2 symptoms, we observed significantly fewer miR-1552/2 com- by guest on September 26, 2021 CD4+ T cells under Th17 cell–skewing conditions (Fig. 4A). pared with miR-155+/+Vb11+CD4+ T cells in the spleens and + + Analysis of these RFP GFP cells by intracellular staining and brains of mice immunized with MOG35–55 (Fig. 6A, 6B, 6E, 6F). FACS revealed defective expression of IL-17A in the absence of Intracellular staining of the recovered T cells revealed that miR- miR-155 compared with Wt controls, and this was statistically 1552/2 cell were defective in their expression of IL-17A (Fig. 6C, significant (Fig. 4C, 4D). Notably, knockdown of Ets1 in miR- 6D, 6G, 6H). In addition, we also observed decreased IL-17A+ 1552/2 cells led to increased amounts of IL-17A+ cells, albeit GM-CSF+ cells in brain with miR-1552/2 cell transfer (Fig. 6H). this did not reach control levels (Fig. 4C, 4D). Moreover, Ets1 It is also of note that there were still reduced EAE symptoms in knockdown significantly increased the expression of other Th17- the absence of miR-155 despite the TCR having a fixed specificity. related genes in miR-1552/2RFP+GFP+ cells, and these included These data demonstrate that miR-155 is required for both the IL-17A, IL-23R, and IL-22 (Fig. 4E). Taken together, these results development and proper function of IL-17F+ Th17 cells during indicate that Ets1 is a functionally relevant target of miR-155 in EAE (Supplemental Fig. 2). Th17 cells. miR-155 is necessary for proper IL-23 responsiveness by miR-155 promotes the function of IL-17F+ Th17 cells during IL-17F+ Th17 cells EAE The IL-23/IL-23R signaling pathway is critical for the expansion To determine whether miR-155 is required for the functionality of Th17 cells in vivo and the induction of EAE in mice, and of differentiated IL-17F+ Th17 cells, we generated miR-155+/+ polymorphisms in the IL-23R gene have been linked to human and miR-1552/2IL-17F RFP+/2 2d2 TCR Tg+ mice (Fig. 5A). autoimmunity (17, 31–33). Because we observed defective ex- 2/2 + The 2D2 TCR specifically recognizes the MOG35–55 peptide, and pression of the IL-23R in miR-155 IL-17F Th17 cells (Fig. T cells expressing this TCR can elicit EAE in mice on a C57BL/6 2D), and reduced numbers of miR-1552/2 Th17 cells during EAE, genetic background (37). By using this new mouse strain, we were we speculated that miR-155 is important for the responsiveness of able to isolate miR-155+/+ or miR-1552/2 IL-17F+ Th17 cells that Th17 cells to IL-23. To test this, we sorted Wt and miR-1552/2 specifically recognize MOG35–55 and test the importance of miR- IL-17F reporter cells following their development in vitro and 155 during Th17 cell encephalogenic function in vivo (Fig. 5B). examined their responsiveness to rIL-23. Following 20 min of We adoptively transferred 2 3 104 in vitro generated miR-155+/+ treatment, miR-155+/+IL-17F+CD4+ T cells had significantly higher or miR-1552/2IL-17F RFP+2d2+CD4+ T cells into Rag12/2 mice levels of activated Stat3 compared with miR-1552/2IL-17F+CD4+ followed by the immunization with MOG35-55 and administration T cells as determined by intracellular staining with an anti–p-Stat3 of pertussis toxin (Fig. 5B). Mice receiving miR-155+/+ IL-17F+ Ab (pY705) and FACS (Fig. 7A, 7B). These data indicate that 2d2+ Th17 cells had a substantially more severe disease course, miR-1552/2IL-17F+ Th17 cells are hyporesponsive to IL-23, likely with higher clinical scores, compared with mice given miR-1552/2 because of reduced IL-23R expression. 6 miR-155 PROMOTES Th17 CELL FUNCTION

+ + FIGURE 5. miR-155 promotes the function of IL-17F 2d2 TCR Tg Downloaded from CD4+ T cells during EAE. (A) Genotyping results conﬁrming the creation of miR-155+/+ or miR-1552/2IL-17F+/2 2D2 TCR Tg+ mice. (B) Sche- matic of the experimental design. (C and D) CD4+ T cells were isolated from miR-155+/+ and miR-1552/2IL-17F RFP+/22D2 TCR Tg+ mice and cultured under Th17 cell–skewing conditions. Seventy-two hours later, IL- 17F RFP+ 2D2 TCR Tg+CD4+ Th17 cells were sorted by FACS and equal 2 2 2 2 numbers of miR-155+/+ or miR-155 / cells were injected into Rag1 / http://www.jimmunol.org/ mice. EAE was induced in both groups by immunizing with 100 mg of the

MOG35–55 peptide. (C) The disease severity was scored regularly based on clinical symptoms (n = 10). (D) Disease incidence was assessed for each group. Error bars represent 6 SEM. *p , 0.05.

2/2 FIGURE 4. Ets1 is a functionally relevant target of miR-155 in Th17 sorted and injected into Rag1 mice followed by induction of 2/2 + 2/2 cells. (A) Schematic of experimental design. (B)miR-155+/+ or miR- EAE (Fig. 7F). Rag1 mice given MIG-IL23R miR-155 IL-

2 2 2 + + by guest on September 26, 2021 155 / IL-17F RFP+/ CD4+ T cells were isolated and infected with a control 17F 2d2 Th17 cells had an earlier onset of disease symptoms, (NC) or Ets1 shRNA–expressing retrovirus. After culturing under Th17 which began on day 12 compared with day 15, and significantly cell–skewing conditions for 72 h, RNA or protein was extracted and ex- higher disease scores compared with mice receiving MIG+ miR- pression of the indicated Th17-related genes were analyzed by qPCR 1552/2IL-17F+2D2+ Th17 cells (Fig. 7G, 7H). Mice receiving (upper panel) or Ets1 by Western blotting (lower panel). (C) miR-155+/+ or + + +/+ + + 2/2 + + MIG or MIG-IL23R miR-155 IL-17F 2d2 Th17 cells had sim- miR-155 RFP GFP T cells were sorted by FACS and subjected to ilar disease courses, with an earlier disease onset and increased intracellular staining for IL-17A. (D) Graph of the average relative per- + + +/+ 2/2 + + severity of symptoms compared with mice having received MIG centage of IL-17A cells in sorted miR-155 or miR-155 RFP GFP + 2/2 + + cells transduced with the control or Ets1 shRNA–expressing retroviral or MIG-IL-23R miR-155 IL-17F 2D2 Th17 cells (Fig. 7G, vector (n = 4, two independent experiments). (E) Expression of Th17 cell 7H). These data provide evidence that one important function of effector genes in sorted miR-1552/2RFP+GFP+ cells transduced with the miR-155 during tissue inflammation is the promotion of IL-23R + control or Ets1 shRNA–expressing retroviral vector were analyzed by expression by IL-17F Th17 cells. qPCR (n = 4). Error bars represent 6 SEM. *p , 0.05. Discussion In this paper, we evaluated the role of miR-155 in developed Th17 In another experiment, brain mononuclear cells were col- cells and made several important discoveries. First, miR-155 is lected from Wt or miR-1552/2 mice 13 d postimmunization with required for expression of several effector genes in differentiated MOG35–55 and restimulated with rIL-23 for 3 d. The expansion of IL-17F–expressing Th17 cells. Second, miR-155 directly targets IL-17A–expressing cells was determined by FACS. Results dem- the transcription factor Ets1, a known negative regulator of Th17 onstrated that Wt CD4+ T cells responded to IL-23 by expressing cell formation. Thus, elevated expression of Ets1 in miR-1552/2 more IL-17A, whereas miR-1552/2CD4+ T cells did not have Th17 cells inhibits effector gene expression. Third, IL-17F+ Th17 a response to IL-23 (Fig. 7C–E). These results further support cells are functionally defective if they lack miR-155, and thus a role for miR-155 in promoting IL-23 responsiveness by Th17 largely incapable of causing severe EAE symptoms like miR-155+/+ cells. controls. Fourth, defective IL-23R expression in miR-1552/2 Th17 Next, we attempted to complement the miR-1552/2 Th17 cell cells results in hyporesponsiveness to IL-23, a pivotal step during phenotype by expressing the IL-23R in miR-1552/2IL-17F+ Th17 Th17 cell pathogenesis. Taken together, these data significantly cells before their adoptive transfer into Rag12/2 mice. Over- advance our understanding of how miR-155 impacts autoimmune expression of IL-23R was achieved by transducing miR-155+/+ inflammation during Th17-dependent disorders. and miR-1552/22D2+CD4+ T cells with MIG-IL-23R or MIG Previous studies have found reduced levels of Th17 cells in control retrovectors, which have been described previously (39). miR-1552/2 mice correlating with decreased autoimmune symp- After retroviral transduction and in vitro skewing, IL-17F+GFP+ toms. However, it has been unclear whether the Th17 cells that are (marking MIG-IL-23R or MIG+ cells) 2D2+ Th17 cells were present in the absence of miR-155 retain normal function on a per The Journal of Immunology 7

FIGURE 6. miR-155 promotes brain inﬁltration and cytokine production by IL-17F+2d2 TCR Tg+CD4+ T cells during EAE. CD4+ T cells were isolated from the spleens and brains of mice following experiments as described in Fig. 5, and (A–H) FACS analysis of the splenocytes (A–D) or brain cells (E–H) was performed. Downloaded from (A) and (E) show the percentage of transferred miR- 155+/+ and miR-1552/2IL-17F+TCR Vb11+CD4+ T cells in each organ, whereas (B)and(F) show data for multiple mice in each group. (C)and(G) are representative FACS plots of IL-17A expression by the recovered T cells, and (D)and(H) show data for multiple mice. The percentage of brain IL-17A+GM-CSF+ cells are also shown in (H). http://www.jimmunol.org/ n = 5 for the miR-155+/+ groups and n = 8 for the miR- 1552/2 groups. Error bars represent 6 SEM. *p , 0.05. by guest on September 26, 2021

cell basis. From a clinical perspective, it is important to determine A previous study found that Ets1 functions downstream of IL-2 whether therapeutic targeting of miR-155 in differentiated, path- to block expression of Th17-related genes (42). Coculture ex- ogenic Th17 cells that have accumulated in inflamed patient tis- periments and exogenous IL-2 delivery demonstrated that Ets1 sues can diminish their functionality and thus disease symptoms. regulates the responsiveness of CD4+ T cells to the inhibitory Our current study demonstrates that miR-1552/2IL-17F+ Th17 effects of IL-2 on Th17 cell development (which appeared in this cells are incapable of causing severe EAE symptoms like their study to be more relevant than its role in promoting IL-2 ex- miR-155+/+ counterparts, and this phenotype is consistent with the pression). The study did not detect Ets1 binding to the IL-17A defective expression of several effector genes including IL-23R. gene promoter, or Ets1-dependent effects on Stat5 activation. These results predict that inhibiting miR-155 could reduce Th17 Thus, the mechanisms by which Ets1 regulates IL-17A and other cell function during human autoimmune disease. Th17 genes (such as IL-23R) in response to IL-2 are unclear. Our The identification of Ets1 as a target of miR-155 in Th17 cells experiments were done without IL-2 blocking Abs or addition of provides insight into the ability of miR-155 to regulate Th17 cell exogenous IL-2. The only IL-2 in the system was produced by the effector function. Ets1 is a well-established negative regulator of activated T cells themselves, and we did not observe differences in Th17 cell development, and also targeted by another miRNA in- the amount of IL-2 expressed by miR-1552/2 versus Wt T cells volved in the formation of Th17 cells, called miR-326 (19, 42). (Supplemental Fig. 3). Thus, the ∼2-fold increase in Ets1 in miR- Thus,Ets1appearstobeacommontargetofmiRNAsinthe 1552/2 cells is not sufficient to increase IL-2 expression in this context of inflammatory Th17 cell biology. Ets1 is mutated in context. Taken together with the study described above, it is pos- patients with certain types of autoimmune conditions, underscoring sible that miR-155 functions to reduce the Ets1-dependent repres- its connection to pathological tissue inflammation (44, 45). Taken sive effects of IL-2 signaling on Th17 cell effector gene expression. together, Ets1 is emerging as an important node in the cellular This will be an area of future investigation. networks that regulate human autoimmunity, and its therapeutic Our study also suggests that multiple targets of miR-155, in manipulation should be examined as a possible treatment. addition to Ets1, are relevant during Th17 cell development and 8 miR-155 PROMOTES Th17 CELL FUNCTION

FIGURE 7. miR-155 promotes IL-23 signaling by IL-17F+ Th17 cells. CD4+ T cells were isolated from miR-155+/+ and miR-1552/2IL-17F RFP+/2 mice and cultured in Th17 condition for 72 h. RFP+ IL-17F+ cells were sorted by FACS and replated in 96-well plates followed by restimulation with IL-23 for 20 min. Cells were subjected to p-STAT3 staining. (A) Representing FACS plot of p-STAT3 staining after IL-23 restimulation. Black lines represent cells without cytokine treatment and red lines represent cells with IL-23. (B) Graphs of the mean ﬂuorescence intensity (MFI) of p-STAT3 (n = 4) before and after IL-23 treatment. Downloaded from (C) Schematic of the experimental design. (D) Representative FACS plots of IL-17A expression + by MOG35–55 restimulated CD4 T cells from the brains Wt and miR-1552/2 EAE mice with and without IL-23 treatment. (E) Data from (D) are shown graphically for multiple mice. (F) Sche- http://www.jimmunol.org/ matic of the experimental design. CD4+ T cells were isolated from miR-155+/+ and miR-1552/2 IL-17F RFP+/22D2 TCR Tg+ mice and infected with a control (MIG) or MIG-IL23R expressing retrovirus. After culturing under Th17 cell–skewing conditions for 72 h, miR-155+/+ or miR-1552/2 IL-17F+2D2 TCR Tg+GFP+CD4+ T cells were sorted by FACS and equal numbers injected into Rag12/2 mice. (G) EAE was induced following the adoptive cell transfer, and disease severity was by guest on September 26, 2021 scored regularly based on clinical symptoms (n =5 for the miR-155+/+ groups and n = 8 for the miR- 1552/2 groups). (H) Disease incidence was also analyzed for each group (n = 5 for miR-155+/+ groups and n = 8 for miR-1552/2 groups). Error bars represent 6 SEM. *p , 0.05.

function. Individual miRNAs have the potential to repress many further highlights the relevance of this pathway during human au- mRNAs. This multitarget nature of miRNAs, in addition to the toimmunity (34–36). Importantly, we found IL-23R to be among the inability of Ets1 knockdown to fully restore expression of Th17- effector genes that is regulated by the miR-155-Ets1 axis in Th17 related genes in miR-1552/2 Th17 cells, indicate that miR-155 cells, and provide evidence that miR-1552/2 Th17 cells are unre- likely targets multiple relevant mRNAs in this cellular compart- sponsive to IL-23 ex vivo. Furthermore, recovery of IL-23R ex- ment. Further experiments will be needed to test whether other pression by miR-1552/2 Th17 cells partially restored EAE disease targets predicted from our ingenuity analysis, or presently un- symptoms. The regulation of this signaling pathway by miR-155 identiﬁed, are being regulated by miR-155 during Th17 cell de- is a promising component of miR-155 biology that has not been velopment and/or function. recognized previously, yet may turn out to be a central mechanism In order for Th17 cells to expand during autoimmunity, they must by which miR-155 promotes autoimmune inﬂammation. be able to respond to IL-23 that is produced by a variety of immune cells within secondary lymphoid organs and lesions that are created Acknowledgments during autoimmunity (31). Certain genetic variants of the IL-23R We thank Allan Bradley for providing miR-1552/2 mice and Chen Dong gene that promote IL-23R function have been associated with hu- for providing the IL-17F RFP reporter mice and the microarray and FACS man autoimmune disorders, including Crohn’s disease and psoria- core facilities at University of Utah. We also thank Angela Presson for help sis, as determined through genome-wide association studies. This with the Ingenuity software. The Journal of Immunology 9

Disclosures 24. Kurowska-Stolarska, M., S. Alivernini, L. E. Ballantine, D. L. Asquith, N. L. Millar, D. S. Gilchrist, J. Reilly, M. Ierna, A. R. Fraser, B. Stolarski, et al. The authors have no financial conflicts of interest. 2011. MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis. Proc. Natl. Acad. Sci. USA 108: 11193–11198. 25. Lu, L. F., T. H. Thai, D. P. Calado, A. Chaudhry, M. Kubo, K. Tanaka, References G. B. Loeb, H. Lee, A. Yoshimura, K. Rajewsky, and A. Y. Rudensky. 2009. 1. Mackay, I. R. 2010. Travels and travails of autoimmunity: a historical journey Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells from discovery to rediscovery. Autoimmun. Rev. 9: A251–A258. by targeting SOCS1 protein. Immunity 30: 80–91. 2. Oukka, M. 2008. Th17 cells in immunity and autoimmunity. Ann. Rheum. Dis. 26. Thai, T. H., D. P. Calado, S. Casola, K. M. Ansel, C. Xiao, Y. Xue, A. Murphy, 67(Suppl. 3): iii26–iii29. D. Frendewey, D. Valenzuela, J. L. Kutok, et al. 2007. Regulation of the germinal 3. Marwaha, A. K., N. J. Leung, A. N. McMurchy, and M. K. Levings. 2012. TH17 center response by microRNA-155. Science 316: 604–608. 27. Chen, D. F., B. D. Gong, Q. Xie, Q. W. Ben, J. Liu, and Y. Z. Yuan. 2010. cells in autoimmunity and immunodeficiency: protective or pathogenic? Front. + Immunol. 3: 129. MicroRNA155 is induced in activated CD4 T cells of TNBS-induced colitis in 4. Bettelli, E., Y. Carrier, W. Gao, T. Korn, T. B. Strom, M. Oukka, H. L. Weiner, mice. World J. Gastroenterol. 16: 854–861. and V. K. Kuchroo. 2006. Reciprocal developmental pathways for the generation 28. Junker, A., M. Krumbholz, S. Eisele, H. Mohan, F. Augstein, R. Bittner, of pathogenic effector TH17 and regulatory T cells. Nature 441: 235–238. H. Lassmann, H. Wekerle, R. Hohlfeld, and E. Meinl. 2009. MicroRNA profiling 5. Mangan, P. R., L. E. Harrington, D. B. O’Quinn, W. S. Helms, D. C. Bullard, of multiple sclerosis lesions identifies modulators of the regulatory protein C. O. Elson, R. D. Hatton, S. M. Wahl, T. R. Schoeb, and C. T. Weaver. 2006. CD47. Brain 132: 3342–3352. Transforming growth factor-beta induces development of the T(H)17 lineage. 29. Wang, G., L. S. Tam, B. C. Kwan, E. K. Li, K. M. Chow, C. C. Luk, P. K. Li, and Nature 441: 231–234. C. C. Szeto. 2012. Expression of miR-146a and miR-155 in the urinary sediment 6. Veldhoen, M., R. J. Hocking, C. J. Atkins, R. M. Locksley, and B. Stockinger. of systemic lupus erythematosus. Clin. Rheumatol. 31: 435–440. 2006. TGFb in the context of an inflammatory cytokine milieu supports de novo 30. Paraboschi, E. M., G. Solda`, D. Gemmati, E. Orioli, G. Zeri, M. D. Benedetti, differentiation of IL-17‑producing T cells. Immunity 24: 179–189. A. Salviati, N. Barizzone, M. Leone, S. Duga, and R. Asselta. 2011. Genetic 7. Zhou, L., I. I. Ivanov, R. Spolski, R. Min, K. Shenderov, T. Egawa, D. E. Levy, association and altered gene expression of mir-155 in multiple sclerosis patients. Int. J. Mol. Sci. 12: 8695–8712.

W. J. Leonard, and D. R. Littman. 2007. IL-6 programs T(H)-17 cell differen- Downloaded from tiation by promoting sequential engagement of the IL-21 and IL-23 pathways. 31. Iwakura, Y., and H. Ishigame. 2006. The IL-23/IL-17 axis in inflammation. J. Nat. Immunol. 8: 967–974. Clin. Invest. 116: 1218–1222. 8. Yang, X. O., A. D. Panopoulos, R. Nurieva, S. H. Chang, D. Wang, 32.Thakker,P.,M.W.Leach,W.Kuang,S.E.Benoit,J.P.Leonard,and S. S. Watowich, and C. Dong. 2007. STAT3 regulates cytokine-mediated gen- S. Marusic. 2007. IL-23 is critical in the induction but not in the effector eration of inflammatory helper T cells. J. Biol. Chem. 282: 9358–9363. phase of experimental autoimmune encephalomyelitis. J. Immunol. 178: 2589– 9. Ivanov, I. I., B. S. McKenzie, L. Zhou, C. E. Tadokoro, A. Lepelley, J. J. Lafaille, 2598. D. J. Cua, and D. R. Littman. 2006. The orphan nuclear receptor RORgt directs 33. Awasthi, A., L. Riol-Blanco, A. Ja¨ger, T. Korn, C. Pot, G. Galileos, E. Bettelli, the differentiation program of proinflammatory IL-17+ T helper cells. Cell 126: V. K. Kuchroo, and M. Oukka. 2009. Cutting edge: IL-23 receptor gfp reporter 1121–1133. mice reveal distinct populations of IL-17-producing cells. J. Immunol. 182: http://www.jimmunol.org/ 10. Veldhoen, M., K. Hirota, A. M. Westendorf, J. Buer, L. Dumoutier, J. C. Renauld, 5904–5908. and B. Stockinger. 2008. The aryl hydrocarbon receptor links TH17-cell-mediated 34. Amre, D. K., D. Mack, D. Israel, K. Morgan, P. Lambrette, L. Law, G. Grimard, autoimmunity to environmental toxins. Nature 453: 106–109. C. Deslandres, A. Krupoves, V. Bucionis, et al. 2008. Association between ge- 11. Schraml, B. U., K. Hildner, W. Ise, W. L. Lee, W. A. Smith, B. Solomon, netic variants in the IL-23R gene and early-onset Crohn’s disease: results from G. Sahota, J. Sim, R. Mukasa, S. Cemerski, et al. 2009. The AP-1 transcription a case-control and family-based study among Canadian children. Am. J. Gas- factor Batf controls T(H)17 differentiation. Nature 460: 405–409. troenterol. 103: 615–620. 12. Bru¨stle, A., S. Heink, M. Huber, C. Rosenpla¨nter, C. Stadelmann, P. Yu, 35. Newman, W. G., Q. Zhang, X. Liu, C. I. Amos, and K. A. Siminovitch. 2009. E. Arpaia, T. W. Mak, T. Kamradt, and M. Lohoff. 2007. The development of Genetic variants in IL-23R and ATG16L1 independently predispose to increased inflammatory T(H)-17 cells requires interferon-regulatory factor 4. Nat. Immu- susceptibility to Crohn’s disease in a Canadian population. J. Clin. Gastro- nol. 8: 958–966. enterol. 43: 444–447. 13. Cua, D. J., J. Sherlock, Y. Chen, C. A. Murphy, B. Joyce, B. Seymour, L. Lucian, 36. Sarin, R., X. Wu, and C. Abraham. 2011. Inflammatory disease protective + W. To, S. Kwan, T. Churakova, et al. 2003. Interleukin-23 rather than R381Q IL23 receptor polymorphism results in decreased primary CD4 and by guest on September 26, 2021 + interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. CD8 human T-cell functional responses. Proc. Natl. Acad. Sci. USA 108: 9560– Nature 421: 744–748. 9565. 14. Langrish, C. L., Y. Chen, W. M. Blumenschein, J. Mattson, B. Basham, 37. Bettelli, E., M. Pagany, H. L. Weiner, C. Linington, R. A. Sobel, and J. D. Sedgwick, T. McClanahan, R. A. Kastelein, and D. J. Cua. 2005. IL-23 V. K. Kuchroo. 2003. Myelin oligodendrocyte glycoprotein-specific T cell re- drives a pathogenic T cell population that induces autoimmune inflammation. J. ceptor transgenic mice develop spontaneous autoimmune optic neuritis. J. Exp. Exp. Med. 201: 233–240. Med. 197: 1073–1081. 15. Aggarwal, S., N. Ghilardi, M. H. Xie, F. J. de Sauvage, and A. L. Gurney. 2003. 38. Yang, X. O., R. Nurieva, G. J. Martinez, H. S. Kang, Y. Chung, B. P. Pappu, Interleukin-23 promotes a distinct CD4 T cell activation state characterized by B. Shah, S. H. Chang, K. S. Schluns, S. S. Watowich, et al. 2008. Molecular the production of interleukin-17. J. Biol. Chem. 278: 1910–1914. antagonism and plasticity of regulatory and inflammatory T cell programs. Im- 16. Murphy, C. A., C. L. Langrish, Y. Chen, W. Blumenschein, T. McClanahan, munity 29: 44–56. R. A. Kastelein, J. D. Sedgwick, and D. J. Cua. 2003. Divergent pro- and 39. Zhou, L., J. E. Lopes, M. M. Chong, I. I. Ivanov, R. Min, G. D. Victora, Y. Shen, antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation. J. J. Du, Y. P. Rubtsov, A. Y. Rudensky, et al. 2008. TGF-beta-induced Foxp3 Exp. Med. 198: 1951–1957. inhibits T(H)17 cell differentiation by antagonizing RORgammat function. Na- 17. McGeachy, M. J., Y. Chen, C. M. Tato, A. Laurence, B. Joyce-Shaikh, ture 453: 236–240. W. M. Blumenschein, T. K. McClanahan, J. J. O’Shea, and D. J. Cua. 2009. The 40. O’Connell, R. M., D. S. Rao, A. A. Chaudhuri, M. P. Boldin, K. D. Taganov, interleukin 23 receptor is essential for the terminal differentiation of interleukin J. Nicoll, R. L. Paquette, and D. Baltimore. 2008. Sustained expression of 17-producing effector T helper cells in vivo. Nat. Immunol. 10: 314–324. microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder. 18. O’Connell, R. M., D. Kahn, W. S. Gibson, J. L. Round, R. L. Scholz, J. Exp. Med. 205: 585–594. A. A. Chaudhuri, M. E. Kahn, D. S. Rao, and D. Baltimore. 2010. MicroRNA- 41. Veldhoen, M., K. Hirota, J. Christensen, A. O’Garra, and B. Stockinger. 2009. 155 promotes autoimmune inflammation by enhancing inflammatory T cell Natural agonists for aryl hydrocarbon receptor in culture medium are essential development. Immunity 33: 607–619. for optimal differentiation of Th17 T cells. J. Exp. Med. 206: 43–49. 19. Du, C., C. Liu, J. Kang, G. Zhao, Z. Ye, S. Huang, Z. Li, Z. Wu, and G. Pei. 42. Moisan, J., R. Grenningloh, E. Bettelli, M. Oukka, and I. C. Ho. 2007. Ets-1 2009. MicroRNA miR-326 regulates TH-17 differentiation and is associated is a negative regulator of Th17 differentiation. J. Exp. Med. 204: 2825– with the pathogenesis of multiple sclerosis. Nat. Immunol. 10: 1252–1259. 2835. 20. O’Connell, R. M., D. S. Rao, A. A. Chaudhuri, and D. Baltimore. 2010. Phys- 43. O’Connell, R. M., A. A. Chaudhuri, D. S. Rao, and D. Baltimore. 2009. Inositol iological and pathological roles for microRNAs in the immune system. Nat. Rev. phosphatase SHIP1 is a primary target of miR-155. Proc. Natl. Acad. Sci. USA Immunol. 10: 111–122. 106: 7113–7118. 21. Ha, T. Y. 2011. MicroRNAs in human diseases: from cancer to cardiovascular 44. Han, J. W., H. F. Zheng, Y. Cui, L. D. Sun, D. Q. Ye, Z. Hu, J. H. Xu, Z. M. Cai, disease. Immune Netw. 11: 135–154. W. Huang, G. P. Zhao, et al. 2009. Genome-wide association study in a Chinese 22. Rodriguez, A., E. Vigorito, S. Clare, M. V. Warren, P. Couttet, D. R. Soond, Han population identifies nine new susceptibility loci for systemic lupus eryth- S. van Dongen, R. J. Grocock, P. P. Das, E. A. Miska, et al. 2007. Requirement of ematosus. Nat. Genet. 41: 1234–1237. bic/microRNA-155 for normal immune function. Science 316: 608–611. 45. Yang, W., N. Shen, D. Q. Ye, Q. Liu, Y. Zhang, X. X. Qian, N. Hirankarn, 23. Kohlhaas, S., O. A. Garden, C. Scudamore, M. Turner, K. Okkenhaug, and D. Ying, H. F. Pan, C. C. Mok, et al. 2010. Genome-wide association study in E. Vigorito. 2009. Cutting edge: the Foxp3 target miR-155 contributes to the Asian populations identifies variants in ETS1 and WDFY4 associated with development of regulatory T cells. J. Immunol. 182: 2578–2582. systemic lupus erythematosus. PLoS Genet. 6: e1000841. Supplemental figure 1

155+/+RFP+ 155-/-RFP+

100

60 * 40 * * * 20

0 % expression of control

A 7F R 1 -17 -23 IL-22 IL IL- IL

Supplemental Figure S1. Percent reduction in Th17 cell effector gene expression in sorted miR-155-/- IL-17F RFP+ cells compared to Wt IL-17F RFP+ controls. * denotes a p value of less than 0.05. Supplemental figure 2

Development Function

CD4+ naiive IL-17F+ RFP+ Transfer equal MOG 35-55 EAE disease T cells Th17 cells number of IL-17F+ Induction of severity Th17 Th17 cells EAE miR-155+/+ Conditions FACS IL17fRFP+/- sort 2d2 TCR+ +++++ Rag-/- miR-155-/- IL17fRFP+/- + 2d2 TCR+ Rag-/-

Supplemental Figure S2. Schematic diagram showing miR-155 is critical for both the development and function of Th17 cells. Supplemental figure 3

IL-2 miR-155+/+ miR-155-/- 25

0 Relative mRNA expression Relative Th17

Supplemental Figure S3. Expression of IL-2 mRNA in Wt compared to miR-155-/- Th17-skewed CD4+ T cells (n=3). Supplemental Table S1. Microarray analysis of sorted miR-155+/+ IL-17F RFP+ versus miR-155-/- IL-17F RFP+ cells. There are two biological replicates for each sample. The ratio is the expression of each gene by miR-155-/- RFP+ cells / expression by Wt RFP+ cells, and the average fluorescence values are on a Log2 scale.

Group 1: WT-RFP+ Group 2: KO-RFP+ Grp1 Mean Grp2 Mean Ratio Direction Gene Identifier Gene Name ENSMUST00000 6.27039 0 77.19 Down 066505 Trans-acting transcription factor 1 (Sp1), mRNA -3.6807 -0.133585 11.69 Up NR_015543 2810055G20Rik -3.82312 -0.27896 11.67 Up AK020539 Transcribed locus 0.766265 4.18313 10.68 Up NM_010558 Interleukin 5 (Il5), mRNA 5.41489 2.08577 10.05 Down NM_010552 Interleukin 17A (Il17a), mRNA 2.700075 -0.569255 9.64 Down NM_144548 Interleukin 23 receptor (Il23r), mRNA -2.224655 1.020455 9.48 Up NM_031168 Interleukin 6 (Il6), mRNA Cyclin-dependent kinase 9 (CDC2-related kinase) 5.40174 2.614375 6.9 Down NM_130860 (Cdk9), mRNA Hematopoietically expressed homeobox (Hhex), 0.476365 3.13177 6.3 Up NM_008245 mRNA Interleukin 17 receptor B, mRNA (cDNA clone -1.59137 1.04016 6.2 Up NM_019583 MGC:35924 IMAGE:5042466) chr17:79042382- -1.32687 -3.932565 6.09 Down 79052046_R chr17:79042382-79052046_R Neuronal guanine nucleotide exchange factor, mRNA (cDNA clone MGC:37278 -2.89186 -0.303855 6.01 Up NM_001111314 IMAGE:4973826) Serine/threonine kinase receptor associated protein 6.24069 3.657415 5.99 Down NM_011499 (Strap), mRNA chr7:134603123- -1.2137 -3.78984 5.96 Down 134614510_F chr7:134603123-134614510_F 4.72279 2.158305 5.92 Down NM_009835 Chemokine (C-C motif) receptor 6 (Ccr6), mRNA Non-functional transcript for T-cell receptor gamma from alloreactive cytotoxic T-cell clone (3F9-gamma -2.0949 0.458515 5.87 Up AK042318 4) V 10.8A-J10.5-C10. UDP-glucose ceramide glucosyltransferase (Ugcg), 5.04379 2.512355 5.78 Down NM_011673 mRNA chr4:21683562- 4.93879 2.42543 5.71 Down 21694350_R chr4:21683562-21694350_R Zinc finger, BED domain containing 4, mRNA 5.16634 2.656435 5.7 Down NM_181412 (cDNA clone IMAGE:4012067) -3.471195 -0.9942 5.57 Up NM_177660 Zbtb10 chr19:53517903- -1.897255 0.557865 5.48 Up 53540753_R chr19:53517903-53540753_R -1.19335 1.25431 5.46 Up NM_001164787 Sprr2a2 4.68164 2.236835 5.44 Down NM_172458 MKIAA3006 protein chr13:23487906- -1.131155 -3.56546 5.41 Down 23488198_F chr13:23487906-23488198_F Mammary tumor virus receptor 2, mRNA (cDNA 7.64879 5.2171 5.4 Down NM_181452 clone MGC:29062 IMAGE:3674980) Mitogen-activated protein kinase kinase kinase 11, 5.32814 2.909295 5.35 Down NM_022012 mRNA (cDNA clone IMAGE:4910665) Mitochondrial ribosomal protein S17, mRNA 6.26069 3.852055 5.31 Down NM_025450 (cDNA clone MGC:6749 IMAGE:3592661) COP9 (constitutive photomorphogenic) homolog, 8.29189 5.90831 5.22 Down NM_012001 subunit 4 (Arabidopsis thaliana) (Cops4), mRNA Pleckstrin homology domain containing, family G (with RhoGef domain) member 2 (Plekhg2), 8.41059 6.03324 5.2 Down NM_138752 transcript variant 1, mRNA -3.77336 -1.40734 5.16 Up NM_153524 MAS-related GPR, member A4 (Mrgpra4), mRNA Family with sequence similarity 60, member A 6.00354 3.6386 5.15 Down NM_019643 (Fam60a), mRNA Catenin (cadherin associated protein), alpha 1 8.50429 6.14402 5.13 Down NM_009818 (Ctnna1), mRNA Stefin A2, mRNA (cDNA clone MGC:169628 4.36825 6.721085 5.11 Up NM_001082545 IMAGE:8861023) Family with sequence similarity 20, member C, -0.868695 -3.219315 5.1 Down NAP020469-001 mRNA (cDNA clone IMAGE:5097853) X-ray repair complementing defective repair in Chinese hamster cells 6, mRNA (cDNA clone 7.94094 5.60022 5.07 Down NM_010247 MGC:18310 IMAGE:3669715) NAD synthetase 1, mRNA (cDNA clone 5.18109 2.85719 5.01 Down NM_030221 MGC:47015 IMAGE:3589586) 6.68364 4.36298 5 Down NM_001009947 Dedicator of cytokinesis 11 (Dock11), mRNA chr18:75513062- -3.0602 -0.74135 4.99 Up 75523889_F chr18:75513062-75523889_F -3.79711 -1.48342 4.97 Up NM_001011851 Olfactory receptor 412 (Olfr412), mRNA 3.800855 6.113435 4.97 Up NM_010137 Endothelial PAS domain protein 1 (Epas1), mRNA 7.44134 5.13194 4.96 Down NM_001159328 Hgs 6.69769 4.390485 4.95 Down AK037728 Transcribed locus Sodium channel, voltage-gated, type III, alpha -1.96109 0.33343 4.91 Up NM_018732 (Scn3a), mRNA GTP binding protein (gene overexpressed in skeletal muscle), mRNA (cDNA clone MGC:36072 6.74014 4.447445 4.9 Down NM_010276 IMAGE:5368352) Non-SMC condensin II complex, subunit H2 7.57784 5.2854 4.9 Down NM_001115132 (Ncaph2), transcript variant 2, mRNA B-cell translocation gene 2, anti-proliferative (Btg2), 5.95454 3.66887 4.88 Down NM_007570 mRNA ATP synthase mitochondrial F1 complex assembly factor 2 (Atpaf2), nuclear gene encoding 4.88519 2.599115 4.88 Down NM_145427 mitochondrial protein, mRNA ENSMUST00000 Sin3-associated polypeptide 18, mRNA (cDNA -2.7175 -0.43497 4.87 Up 124622 clone MGC:11444 IMAGE:3968600) RIKEN cDNA 3110057O12 gene, mRNA (cDNA 5.87954 3.594315 4.87 Down NM_026622 clone IMAGE:4007705) 6.32684 4.04166 4.87 Down NM_028242 HIV TAT specific factor 1 (Htatsf1), mRNA Pellino 2, mRNA (cDNA clone MGC:38603 1.44357 -0.823835 4.81 Down NM_033602 IMAGE:5355240) Cbp/p300-interacting transactivator, with Glu/Asp- 5.48729 3.22311 4.8 Down NM_010828 rich carboxy-terminal domain, 2 (Cited2), mRNA RIKEN cDNA 1110054O05 gene, mRNA (cDNA 5.20789 2.95854 4.75 Down NM_001013577 clone MGC:143498 IMAGE:40090152) Dystroglycan 1, mRNA (cDNA clone MGC:6651 4.92334 2.67531 4.75 Down NM_010017 IMAGE:3496914) 5.02889 2.791955 4.71 Down NM_001206684 2610528A11Rik 4.96444 2.72873 4.71 Down NM_001033767 Predicted gene, EG240327 (EG240327), mRNA Protein phosphatase 2 (formerly 2A), regulatory 8.08434 5.853055 4.7 Down NM_028032 subunit B (PR 52), alpha isoform (Ppp2r2a), mRNA chr18:5119300- -2.765525 -0.53477 4.69 Up 5181600_F chr18:5119300-5181600_F 5.14589 2.91589 4.69 Down XM_987328 Gm7241 chr19:53517903- -1.393525 0.833885 4.68 Up 53540753_R chr19:53517903-53540753_R chr13:94200051- 4.95609 2.729545 4.68 Down 94200598_R chr13:94200051-94200598_R Solute carrier family 15 (H+/peptide transporter), 6.33829 4.111655 4.68 Down NM_021301 member 2, mRNA (cDNA clone IMAGE:3583898) Wolf-Hirschhorn syndrome candidate 1-like 1 8.00269 5.78387 4.66 Down NM_001001735 (human) (Whsc1l1), transcript variant 2, mRNA -1.73787 -3.9566 4.65 Down NM_027366 Ly6g6e protein isoform A, splice variant 1 4.53949 2.32166 4.65 Down NM_001166623 Rbmx RIKEN cDNA 9030624J02 gene, mRNA (cDNA 7.39119 5.173845 4.65 Down NM_027815 clone IMAGE:3988425) GATA zinc finger domain containing 2B (Gatad2b), 4.67829 2.463085 4.64 Down NM_139304 mRNA chr8:72663625- 4.91714 2.703465 4.64 Down 72673010_F chr8:72663625-72673010_F RIKEN cDNA 4732471D19 gene, mRNA (cDNA 4.44804 2.234605 4.64 Down NM_176987 clone IMAGE:5357053) MAP kinase-activated protein kinase 5, mRNA 4.19424 1.98124 4.64 Down A_55_P2049261 (cDNA clone MGC:29084 IMAGE:5010305) -1.20924 -3.42017 4.63 Down C80425 Transcribed locus Glucosamine-phosphate N-acetyltransferase 1, mRNA (cDNA clone MGC:35936 5.11439 2.902185 4.63 Down NM_019425 IMAGE:5065641) Mitochondrial ribosomal protein L49, mRNA 5.62774 3.4173 4.63 Down NM_026246 (cDNA clone MGC:35661 IMAGE:5368499) DEAH (Asp-Glu-Ala-His) box polypeptide 29, 11.85809 9.657735 4.6 Down NAP061267-1 mRNA (cDNA clone IMAGE:1493891) Membrane-associated ring finger (C3HC4) 6, -1.623425 -3.81618 4.57 Down A_55_P2038514 mRNA (cDNA clone IMAGE:4238874) CD44 antigen, mRNA (cDNA clone 0.17772 -2.013695 4.57 Down NM_009851 IMAGE:3153835) -0.958165 -3.140435 4.54 Down NM_001205234 Nrxn2 DnaJ (Hsp40) homolog, subfamily C, member 8, 7.41974 5.237375 4.54 Down NM_172400 mRNA (cDNA clone IMAGE:5371537) 6.78399 4.60539 4.53 Down NM_194336 Guanylate-binding protein 10 (Gbp10) 10.70829 8.537485 4.5 Down A_55_P1972969 Strain ILS Kex2-like protein Sirtuin 5 (silent mating type information regulation 2 homolog) 5 (S. cerevisiae), mRNA (cDNA clone 4.82239 2.655065 4.49 Down NM_178848 MGC:18762 IMAGE:4014119) 7.29539 5.127335 4.49 Down NM_145856 Interleukin 17F (Il17f), mRNA Cytokine induced apoptosis inhibitor 1, mRNA 6.52504 4.36494 4.47 Down NM_134141 (cDNA clone MGC:29983 IMAGE:5123958) Brain protein 44-like, mRNA (cDNA clone 10.94789 8.793885 4.45 Down NAP111971-1 MGC:35947 IMAGE:4988147) Phospholipase D family, member 5, mRNA (cDNA 7.66699 5.524345 4.42 Down NAP114927-1 clone MGC:118236 IMAGE:30247182) Homeodomain leucine zipper-encoding gene, mRNA 4.371345 2.230875 4.41 Down NM_183174 (cDNA clone MGC:102227 IMAGE:30616315) Coiled-coil domain containing 33, mRNA (cDNA 1.97778 4.11617 4.4 Up NM_029212 clone MGC:143911 IMAGE:40094912) Sorting nexin 12, mRNA (cDNA clone MGC:5791 6.29564 4.162725 4.39 Down NM_001110310 IMAGE:3592627) HMG box domain containing 4, mRNA (cDNA 4.84304 2.721405 4.35 Down NM_178017 clone IMAGE:4948318) Homer homolog 1 (Drosophila) (Homer1), transcript 3.814515 1.69291 4.35 Down NM_147176 variant L, mRNA 0.788875 2.9058 4.34 Up NM_010137 Endothelial PAS domain protein 1 (Epas1), mRNA PHD finger protein 20-like 1, mRNA (cDNA clone 4.408665 2.28984 4.34 Down NM_001081409 MGC:175576 IMAGE:40130992) 4.96849 2.85544 4.33 Down NM_139063 Muted (Muted), mRNA 7.24209 5.131615 4.32 Down NM_001242389 Trip10 RIKEN cDNA 2810452K22 gene (2810452K22Rik), 4.92599 2.81527 4.32 Down NM_026048 mRNA CDNA fis, clone TRACH2005666,highly similar to Mouse mRNA for phosphatidylinositol 4-phosphate 5.90359 3.795445 4.31 Down NM_008847 5-kinase type I-beta Male enhanced antigen 1, mRNA (cDNA clone 6.27774 4.16984 4.31 Down NM_010787 MGC:14069 IMAGE:4035701) NOP14 nucleolar protein homolog (yeast), mRNA 5.00119 2.89461 4.31 Down NM_029278 (cDNA clone MGC:32275 IMAGE:5012070) chr3:37659958- -0.916605 -3.015195 4.28 Down 37665945_F chr3:37659958-37665945_F NIMA (never in mitosis gene a)-related expressed kinase 6, mRNA (cDNA clone MGC:28570 6.57389 4.475605 4.28 Down NM_021606 IMAGE:4209097) chr17:39960567- 7.27904 5.18347 4.27 Down 39992817_R chr17:39960567-39992817_R DAZ interacting protein 1, mRNA (cDNA clone -1.14206 -3.22402 4.23 Down NM_025943 MGC:106777 IMAGE:6825425) Zinc finger protein 157, mRNA (cDNA clone 0.37094 -1.70537 4.22 Down NM_028130 MGC:67605 IMAGE:6409233) Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C (Sema3c), -2.53755 -0.463325 4.21 Up NM_013657 mRNA 10.57904 8.510135 4.2 Down NR_033633 Gm8709 Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 5.73709 3.66986 4.19 Down NM_022328 (Mllt1), mRNA 4.07627 6.132685 4.16 Up NM_008355 Interleukin 13 (Il13), mRNA 5.36364 3.30876 4.16 Down NM_176923 CDW12/WDR59 Strain ICR endothelial and smooth muscle cell- -1.744475 -3.794095 4.14 Down NM_028523 derived neuropilin-like protein (Esdn) WW domain containing transcription regulator 1, -1.20848 -3.255515 4.13 Down NM_133784 mRNA (cDNA clone IMAGE:5011849) Glutathione peroxidase 3 (Gpx3), transcript variant -1.198375 0.849155 4.13 Up NM_008161 2, mRNA Transcribed locus, strongly similar to XP_001472420.1 PREDICTED: hypothetical protein 0.696165 2.741095 4.13 Up AK146072 [Mus musculus] Eukaryotic translation initiation factor 4A2 (Eif4a2), 9.02484 6.979085 4.13 Down NM_001123038 transcript variant 1, mRNA Tetratricopeptide repeat domain 21B (Ttc21b), 0.93545 -1.09857 4.1 Down NM_001047604 mRNA chr19:53517903- -0.63705 1.38725 4.07 Up 53540753_R chr19:53517903-53540753_R -2.742355 -0.71589 4.07 Up NM_001033534 Layn 0.987885 3.006855 4.05 Up NM_001169153 Cd300lf Non-SMC condensin I complex, subunit H (Ncaph), 8.28364 6.27153 4.03 Down NM_144818 mRNA G protein-coupled receptor 77 (Gpr77), transcript 0.62955 -1.375075 4.01 Down NM_176912 variant 2, mRNA 4.58599 2.5821 4.01 Down NM_001099349 Gm14308 chr11:59217249- -0.861625 -2.858215 3.99 Down 59217785_R chr11:59217249-59217785_R chr16:50715231- -1.50679 0.48852 3.99 Up 50841124_F chr16:50715231-50841124_F RIKEN cDNA 2310008H09 gene (2310008H09Rik), 3.946185 1.95113 3.99 Down NM_023197 mRNA -0.938455 1.05458 3.98 Up NM_133977 Transferrin (Trf), mRNA Eyes absent 2 homolog (Drosophila), mRNA (cDNA 1.19279 3.186725 3.98 Up NM_010165 clone MGC:5883 IMAGE:3497245) MFNG O-fucosylpeptide 3-beta-N- acetylglucosaminyltransferase, mRNA (cDNA clone 8.43114 6.439735 3.98 Down NM_008595 MGC:13899 IMAGE:3980692) chr4:21683562- -1.56266 -3.54808 3.96 Down 21694344_R chr4:21683562-21694344_R 5.48089 3.493585 3.96 Down A_55_P2134032 Cystic fibrosis transmembrane conductance regulator homolog (Cftr), mRNA Microspherule protein 1, mRNA (cDNA clone 6.96784 4.98408 3.96 Down NM_016766 MGC:5852 IMAGE:3486681) PRP39 pre-mRNA processing factor 39 homolog 4.68819 2.702435 3.96 Down NM_177806 (yeast), mRNA (cDNA clone IMAGE:4951324) Zinc finger protein 422, mRNA (cDNA clone 10.07529 8.095235 3.95 Down NAP096498-001 MGC:6394 IMAGE:3583940) Peptidyl prolyl isomerase H (Ppih), transcript variant 5.33514 3.357365 3.94 Down NM_001110130 2, mRNA Succinate-CoA ligase, GDP-forming, alpha subunit, mRNA (cDNA clone MGC:18990 8.48869 6.51189 3.94 Down NM_019879 IMAGE:4012310) Uridine-cytidine kinase 1-like 1, mRNA (cDNA 6.14634 4.17096 3.93 Down NM_026765 clone MGC:27764 IMAGE:2655873) Bystin-like, mRNA (cDNA clone MGC:27710 6.59769 4.62606 3.92 Down NM_016859 IMAGE:4925307) chr11:97275905- -1.237475 -3.205945 3.91 Down 97310538_R chr11:97275905-97310538_R RIKEN cDNA 2510009E07 gene (2510009E07Rik), -0.269865 -2.23775 3.91 Down NM_001001881 mRNA Ubiquitin C, mRNA (cDNA clone 11.06734 9.103235 3.9 Down NM_019639 IMAGE:2645223) Tetratricopeptide repeat domain 7, mRNA (cDNA 7.51944 5.556315 3.9 Down NM_028639 clone IMAGE:5346075) Coxsackie virus and adenovirus receptor, mRNA -1.40065 -3.361055 3.89 Down NM_001025192 (cDNA clone MGC:25298 IMAGE:4216727) 8.80149 6.840535 3.89 Down NEAT1 NEAT1 G1 to S phase transition 1 (Gspt1), transcript variant 8.40419 6.447385 3.88 Down NM_146066 1, mRNA Non-SMC condensin II complex, subunit G2 5.52314 3.56584 3.88 Down NM_133762 (Ncapg2), mRNA 9.01824 7.067535 3.87 Down NM_001204875 Set RIKEN cDNA 4933433P14 gene, mRNA (cDNA 3.86329 1.90972 3.87 Down NM_178613 clone MGC:27787 IMAGE:3156862) Coactivator-associated arginine methyltransferase 1, mRNA (cDNA clone MGC:46828 5.41359 3.467355 3.85 Down NM_153141 IMAGE:4935077) chr4:44240894- -2.90849 -0.96717 3.84 Up 44241570_R chr4:44240894-44241570_R 4.85229 2.915235 3.83 Down AK017951 Transcribed locus chr19:53517903- -0.80465 1.129275 3.82 Up 53540753_R chr19:53517903-53540753_R Stefin A2 like 1, mRNA (cDNA clone MGC:155670 2.98615 4.919335 3.82 Up NM_173869 IMAGE:8734103) chr13:23517278- -0.564475 -2.495095 3.81 Down 23523756_F chr13:23517278-23523756_F 0.1454 2.075625 3.81 Up NM_001082543 Stefin A1 (Stfa1), mRNA 6.76644 4.83671 3.81 Down NM_001205353 Gramd4 Solute carrier family 25 (mitochondrial carrier, ENSMUST00000 dicarboxylate transporter), member 10, mRNA -0.52911 -2.456285 3.8 Down 038612 (cDNA clone MGC:7207 IMAGE:34823 -1.30214 -3.22477 3.79 Down XR_105442 Gm12059 Hydroxymethylbilane synthase, mRNA (cDNA 6.29239 4.370905 3.79 Down BC003861 clone MGC:6604 IMAGE:3487642) chr14:43408099- -3.341465 -1.425745 3.77 Up 43415349_F chr14:43408099-43415349_F 6.36739 4.4523 3.77 Down NR_003631 Gm6578 ENSMUST00000 Benzodiazapine receptor associated protein 1, 0.460765 2.37011 3.76 Up 107932 mRNA (cDNA clone IMAGE:6400807) TM2 domain containing 3 (Tm2d3), transcript 6.51774 4.609 3.75 Down NM_178056 variant 1, mRNA CDNA sequence BC057893, mRNA (cDNA clone 5.32384 3.420575 3.74 Down NM_173033 MGC:67667 IMAGE:4978941) Intraflagellar transport 88 homolog (Chlamydomonas), mRNA (cDNA clone 4.354325 2.452625 3.74 Down NM_009376 MGC:18440 IMAGE:4019334) 1.22945 3.1303 3.73 Up NM_174857 MAM domain containing 2 (Mamdc2), mRNA Natriuretic peptide receptor 3 (Npr3), transcript -1.77326 -3.66795 3.72 Down NM_008728 variant 1, mRNA PREDICTED: Mus musculus hypothetical protein -3.277625 -1.382405 3.72 Up A_55_P2136010 LOC100042628 (LOC100042628), mRNA Neuron navigator 2, mRNA (cDNA clone -1.42441 -3.31649 3.71 Down NM_175272 IMAGE:9087590) chr3:26975624- -2.64865 -0.760485 3.7 Up 26988699_R chr3:26975624-26988699_R ENSMUST00000 RIKEN cDNA 1500001M20 gene 4.23005 2.34083 3.7 Down 101568 (1500001M20Rik), mRNA Transmembrane protein 107 (Tmem107), transcript 5.81929 3.93623 3.69 Down NM_025838 variant 1, mRNA chr12:81217572- -1.428675 -3.299245 3.66 Down 81233910_F chr12:81217572-81233910_F PREDICTED: Mus musculus hypothetical protein -3.297935 -1.426065 3.66 Up BM939002 LOC100039533 (LOC100039533), mRNA Tissue inhibitor of metalloproteinase 2 (Timp2), 5.54539 3.67168 3.66 Down NM_011594 mRNA chr19:53517903- 0.69737 2.56098 3.64 Up 53540753_R chr19:53517903-53540753_R Solute carrier family 35 (UDP-glucuronic acid/UDP- N-acetylgalactosamine dual transporter), member 4.147105 2.28408 3.64 Down NM_177732 D1, mRNA (cDNA clone MGC:14 chr6:112552041- -0.65872 -2.52043 3.63 Down 112560067_R chr6:112552041-112560067_R Arginase, liver, mRNA (cDNA clone MGC:13983 2.369935 4.230025 3.63 Up NM_007482 IMAGE:4163626) CTAGE family, member 5, mRNA (cDNA clone 6.69979 4.83959 3.63 Down NM_146034 IMAGE:5097489) -3.01738 -1.160475 3.62 Up NM_146956 Olfactory receptor 525, mRNA (cDNA clone MGC:170873 IMAGE:8862268) 4.84499 2.991505 3.61 Down NM_025828 Lectin, mannose-binding 2 (Lman2), mRNA RIKEN cDNA 4930555G01 gene (4930555G01Rik), 7.09494 8.938085 3.59 Up A_55_P2129469 mRNA -1.339505 -3.178595 3.58 Down NM_146865 Olfactory receptor 992 (Olfr992), mRNA WAP four-disulfide core domain 16, mRNA (cDNA -2.268615 -0.429055 3.58 Up NM_001012723 clone MGC:175857 IMAGE:40131273) chr10:66627543- 3.873755 2.032395 3.58 Down 66629331_F chr10:66627543-66629331_F chr15:68161768- 3.587285 1.75216 3.57 Down 68193518_R chr15:68161768-68193518_R 6.31654 4.48072 3.57 Down NM_172428 Mus musculus, clone IMAGE:3500870, mRNA chr17:26911032- 4.203935 2.37068 3.56 Down 26912366_F chr17:26911032-26912366_F Aspartyl-tRNA synthetase (Dars), transcript variant 5.58904 3.7558 3.56 Down NM_177445 2, mRNA DEAD (Asp-Glu-Ala-Asp) box polypeptide 39, mRNA (cDNA clone MGC:28113 8.58429 6.751185 3.56 Down NM_197982 IMAGE:3969048) chr5:22801058- -1.67691 -3.50468 3.55 Down 22939737_F chr5:22801058-22939737_F Cytochrome P450, family 1, subfamily b, 0.57593 -1.25015 3.55 Down AK076360 polypeptide 1 (Cyp1b1), mRNA Transcribed locus, strongly similar to XP_001480002.1 PREDICTED: similar to 4.49744 2.682685 3.52 Down AK139675 elongation factor 1 homolog (S. cerevisiae) [Mus chr9:75316422- -0.875015 -2.684885 3.51 Down 75332567_F chr9:75316422-75332567_F 5.34639 3.53407 3.51 Down XM_001478694 Gm3993 chr14:44292637- 8.59279 6.781085 3.51 Down 44293014_F chr14:44292637-44293014_F DnaJ (Hsp40) homolog, subfamily C, member 10, ENSMUST00000 mRNA (cDNA clone MGC:28281 1.81044 3.618755 3.5 Up 103564 IMAGE:4010341) 4.000185 2.193705 3.5 Down AK037550 Transcribed locus RIKEN cDNA 1700001P01 gene (1700001P01Rik), -0.950755 -2.75204 3.49 Down NM_028156 mRNA chr8:94841965- -3.19498 -1.390755 3.49 Up 94881130_R chr8:94841965-94881130_R Transcribed locus, weakly similar to XP_001479644.1 PREDICTED: hypothetical protein 3.41419 1.613425 3.48 Down AK133873 [Mus musculus] Fibrinogen-like protein 2, mRNA (cDNA clone 1.374045 3.169945 3.47 Up NM_008013 MGC:19044 IMAGE:4189071) Telomeric repeat binding factor 2 (Terf2), transcript 6.79154 4.99572 3.47 Down NM_009353 variant 1, mRNA RIKEN cDNA 2310003C23 gene (2310003C23Rik), 4.47029 2.676695 3.47 Down NM_029607 mRNA ENSMUST00000 9.47424 7.678985 3.47 Down 090234 Predicted gene, EG436003 (EG436003), mRNA RNA and export factor binding protein 1-II (REF1 8.04524 6.250585 3.47 Down NM_011568 gene) TRAF family member-associated Nf-kappa B activator, mRNA (cDNA clone MGC:13977 3.859285 2.06693 3.46 Down NM_011529 IMAGE:3492937) Killer cell lectin-like receptor subfamily G, member -1.14936 0.636955 3.45 Up NM_016970 1 (Klrg1), mRNA 3.83304 2.047015 3.45 Down NM_178922 Hypermethylated in cancer 2 protein (Hic2) Glutathione reductase, mRNA (cDNA clone 7.30134 5.515345 3.45 Down NM_010344 IMAGE:3589654) 5.40284 3.617005 3.45 Down NM_019994 GAP-related interacting partner to E12 -2.433925 -0.650695 3.44 Up NM_001033228 Pelota homolog (Drosophila) (Pelo), mRNA DnaJ (Hsp40) homolog, subfamily C, member 10, ENSMUST00000 mRNA (cDNA clone MGC:28281 2.823405 4.601235 3.43 Up 103566 IMAGE:4010341) Hepatitis A virus cellular receptor 2 (Havcr2), 0.65621 2.42997 3.42 Up NM_134250 mRNA 7.84154 6.069635 3.42 Down NM_010918 Cyclophilin-related protein chr11:117835849 -0.758105 -2.52845 3.41 Down -117842574_R chr11:117835849-117842574_R -1.679275 -3.44614 3.4 Down AK008051 Transcribed locus S100 calcium binding protein A10 (calpactin), mRNA (cDNA clone MGC:36182 8.85334 7.086685 3.4 Down NM_009112 IMAGE:4949465) chr8:71938275- -0.86847 -2.628335 3.39 Down 72113375_F chr8:71938275-72113375_F -0.226915 -1.989985 3.39 Down A_55_P2052709 CDNA clone IMAGE:40099060 RIKEN cDNA 2900011O08 gene (2900011O08Rik), 3.333585 1.5731 3.39 Down NM_144518 mRNA -2.44604 -0.689135 3.38 Up NM_147095 Olfactory receptor 676 (Olfr676), mRNA 2.880935 4.633535 3.37 Up NR_028427 5830416P10Rik Mitochondrial ribosomal protein S17, mRNA 6.79469 5.044055 3.37 Down NM_025450 (cDNA clone MGC:6749 IMAGE:3592661) Cytotoxic T lymphocyte-associated protein 2 alpha, mRNA (cDNA clone MGC:41186 11.05954 9.310535 3.36 Down NM_007797 IMAGE:1244311) -1.12844 -2.873345 3.35 Down AK015406 Transcribed locus UDP-GlcNAc:betaGal beta-1,3-N- acetylglucosaminyltransferase 1, mRNA (cDNA 5.37439 3.63087 3.35 Down NM_175383 clone IMAGE:3488094) Lectin, galactose binding, soluble 9, mRNA (cDNA 4.85421 3.115745 3.34 Down NM_010708 clone MGC:5882 IMAGE:3601419) chr1:163508244- 4.95789 3.219515 3.34 Down 163586072_F chr1:163508244-163586072_F Male germ cell-associated kinase (Mak), transcript -2.655435 -0.923265 3.32 Up NM_008547 variant 2, mRNA chr5:106982442- -3.044445 -1.313485 3.32 Up 107045717_R chr5:106982442-107045717_R Myxovirus (influenza virus) resistance 2, mRNA 1.229335 -0.499745 3.32 Down NM_013606 (cDNA clone MGC:5689 IMAGE:3591798) Catenin (cadherin associated protein), alpha-like 1 -1.342505 -3.069405 3.31 Down NM_018761 (Ctnnal1), mRNA chr19:53517903- -0.503055 1.223525 3.31 Up 53540753_R chr19:53517903-53540753_R Staphylococcal nuclease and tudor domain containing 1, mRNA (cDNA clone MGC:5677 5.41329 3.68633 3.31 Down NM_019776 IMAGE:3592548) Pleiomorphic adenoma gene-like 2, mRNA (cDNA 4.615405 2.8875 3.31 Down NM_018807 clone IMAGE:5401617) 4.50789 2.78481 3.3 Down NM_001195390 Commd7 Hemolytic complement, mRNA (cDNA clone 3.845465 5.564685 3.29 Up NM_010406 IMAGE:3488145) ENSMUST00000 0.80399 2.51657 3.28 Up 103554 ENSMUST00000103554 chr7:99879368- 0.27862 -1.43556 3.28 Down 99889978_R chr7:99879368-99889978_R -0.53208 -2.23978 3.27 Down NM_175122 Rab39B ATP-binding cassette, sub-family C (CFTR/MRP), member 4, mRNA (cDNA clone MGC:183733 3.95544 2.24712 3.27 Down NM_001033336 IMAGE:9087733) -1.319235 -3.02213 3.26 Down NM_001164676 Zfp229 -2.850565 -1.144115 3.26 Up NM_023456 Neuropeptide Y (Npy), mRNA chr10:109653855 -0.57731 -2.27873 3.25 Down -109858347_R chr10:109653855-109858347_R RIKEN cDNA A630038E17 gene, mRNA (cDNA 1.788975 3.490225 3.25 Up AK153587 clone IMAGE:4168121) PREDICTED: Mus musculus predicted gene, 12.11249 10.412585 3.25 Down A_55_P2016968 EG665189 (EG665189), mRNA Family with sequence similarity 38, member B, ENSMUST00000 mRNA (cDNA clone MGC:182702 -1.195625 -2.892055 3.24 Down 090293 IMAGE:9056596) chr3:96205072- -1.643165 -3.33931 3.24 Down 96205937_R chr3:96205072-96205937_R 5-hydroxytryptamine (serotonin) receptor 2A, ENSMUST00000 mRNA (cDNA clone MGC:124302 -3.02162 -1.32416 3.24 Up 144837 IMAGE:40047364) 2.157725 0.461325 3.24 Down NM_153553 Neuronal PAS domain protein 4 (Npas4), mRNA chr16:44717531- -1.33027 -3.023035 3.23 Down 44724206_F chr16:44717531-44724206_F 5.66469 7.355135 3.23 Up NM_010371 Granzyme C (Gzmc), mRNA chr4:21683562- -0.71249 -2.399285 3.22 Down 21694344_R chr4:21683562-21694344_R Superkiller viralicidic activity 2-like 2 (S. cerevisiae) 6.80799 5.121275 3.22 Down NM_028151 (Skiv2l2), mRNA 5.68774 3.99897 3.22 Down NM_008798 Programmed cell death 1 (Pdcd1), mRNA Phosphatidylinositol glycan anchor biosynthesis, class F, mRNA (cDNA clone MGC:18392 5.42564 3.73747 3.22 Down NM_008838 IMAGE:3673399) -1.033065 -2.714535 3.21 Down NM_010029 Drosophila vasa homologue chr1:193048332- -0.313095 -1.99549 3.21 Down 193049714_F chr1:193048332-193049714_F Killer cell lectin-like receptor subfamily A, member 0.371905 2.0563 3.21 Up NM_010650 21 (Klra21), mRNA -1.37557 -3.05544 3.2 Down NM_027604 Ubiquitin specific peptidase 15 (Usp15), mRNA Clone H166 monoclonal autoantibody light chain -1.16844 -2.845965 3.2 Down U18580 variable region 0.902245 -0.77068 3.19 Down AK075724 CDNA clone IMAGE:6811931 CDNA fis, clone TRACH2014573,highly similar to ASPARTATE AMINOTRANSFERASE, 7.38264 5.71053 3.19 Down NM_010325 MITOCHONDRIAL PRECURSOR (EC 2.6.1.1) chr17:46972160- 3.740155 2.065895 3.19 Down 46997919_R chr17:46972160-46997919_R Family with sequence similarity 26, member F, mRNA (cDNA clone MGC:106111 0.404 2.07257 3.18 Up NM_175449 IMAGE:4945137) 6.73784 5.06739 3.18 Down NM_011364 SH2 domain protein 1A (Sh2d1a), mRNA -0.488785 -2.15338 3.17 Down NR_003519 Pisd-ps2 Vasoactive intestinal peptide receptor 2 (Vipr2), 3.68039 2.016775 3.17 Down A_55_P2033680 mRNA Syntaxin 5A, mRNA (cDNA clone MGC:25518 6.21304 4.54807 3.17 Down A_55_P1962982 IMAGE:3487476) Aquaporin 9, mRNA (cDNA clone MGC:35844 -0.530325 1.1288 3.16 Up NM_022026 IMAGE:5096952) Suppressor of Ty 7 (S. cerevisiae)-like, mRNA -0.416925 -2.078415 3.16 Down NM_028150 (cDNA clone MGC:25489 IMAGE:4502314) Killer cell lectin-like receptor subfamily A, member 1.980665 3.640375 3.16 Up NM_024470 12 (Klra12), mRNA ENSMUST00000 3.62896 5.289235 3.16 Up 103558 Myotubularin related protein 1 (Mtmr1), mRNA Coatomer protein complex, subunit zeta 1, mRNA 8.70244 7.044685 3.16 Down NM_019817 (cDNA clone MGC:37172 IMAGE:4954031) 10.49959 8.838585 3.16 Down NM_009128 Fatty acid desaturase (Scd3) Microrchidia 1, mRNA (cDNA clone MGC:31502 -2.858605 -1.201665 3.15 Up NM_010816 IMAGE:4487929) -2.33642 -0.68144 3.15 Up NM_001177887 Igsf5 chr1:141070245- 4.85864 3.20193 3.15 Down 141076841_F chr1:141070245-141076841_F Transmembrane protein 176A (Tmem176a), 4.087075 2.432145 3.15 Down NM_025326 transcript variant 1, mRNA Interphotoreceptor matrix proteoglycan 2, mRNA 0.98069 -0.67297 3.15 Down NM_174876 (cDNA clone MGC:55121 IMAGE:5368568) -1.79022 -3.44127 3.14 Down chr15:96984422- chr15:96984422-97000322_F 97000322_F CD8 antigen, alpha chain, mRNA (cDNA clone -0.553055 1.09897 3.14 Up NM_001081110 MGC:41580 IMAGE:1247019) 4.83729 3.1854 3.14 Down NM_207654 Ephrin A5 (Efna5), transcript variant 2, mRNA 3.890985 2.24095 3.14 Down NM_144786 Gamma-glutamyltransferase 7 (Ggt7), mRNA Amine oxidase (flavin containing) domain 2, mRNA 7.20884 5.55612 3.14 Down NM_133872 (cDNA clone IMAGE:4019315) Ribosomal protein L38 (Rpl38), transcript variant 2, 12.35094 10.698535 3.14 Down NM_001048057 mRNA chr3:125556184- -1.736145 -3.382345 3.13 Down 125556476_R chr3:125556184-125556476_R chr4:54851872- -1.08359 -2.73081 3.13 Down 54866706_R chr4:54851872-54866706_R -1.63137 -3.27083 3.12 Down NM_008560 Melanocortin 2 receptor (Mc2r), mRNA PREDICTED: Mus musculus predicted gene, 0.58615 -1.05374 3.12 Down BC048373 EG665338, transcript variant 2 (EG665338), mRNA Family with sequence similarity 171, member A1, 0.767025 -0.874715 3.12 Down NM_001081161 mRNA (cDNA clone IMAGE:5375863) 0.11191 -1.529655 3.12 Down A_55_P2048957 A_55_P2048957 6.49124 4.848115 3.12 Down NM_001159617 Pigp 12.61584 10.974185 3.12 Down XM_003084649 LOC639606 chr7:141616960- -1.651725 -3.289615 3.11 Down 141690667_R chr7:141616960-141690667_R -2.444115 -0.8109 3.1 Up XM_621555 Olfr1175-ps ENSMUST00000 1.831905 3.46564 3.1 Up 103559 ENSMUST00000103559 Bcl6 interacting corepressor, mRNA (cDNA clone 6.90919 5.276795 3.1 Down NM_029510 IMAGE:1379440) -2.716525 -1.0881 3.09 Up NM_011866 CAMP/cGMP phosphodiesterase (Pde10a) chr13:23488256- -1.460285 -3.08645 3.09 Down 23488626_F chr13:23488256-23488626_F NADH dehydrogenase (ubiquinone) Fe-S protein 5 9.27229 7.644335 3.09 Down NM_001030274 (Ndufs5), mRNA ENSMUST00000 GDP-mannose pyrophosphorylase A (Gmppa), -2.27545 -0.651555 3.08 Up 103324 mRNA chr15:77164450- 6.35089 4.73317 3.07 Down 77201325_F chr15:77164450-77201325_F V-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian), mRNA (cDNA clone 0.37398 1.98648 3.06 Up NM_008709 MGC:6240 IMAGE:3495446) Dolichol-phosphate (beta-D) mannosyltransferase 2, 7.07544 5.46061 3.06 Down NM_010073 mRNA (cDNA clone MGC:6506 IMAGE:2648752) Immunoglobulin heavy chain complex, mRNA -1.156525 -2.7659 3.05 Down BC019425 (cDNA clone MGC:30284 IMAGE:4205959) -2.2688 -0.659335 3.05 Up AK148881 Scn3a chr9:20313342- 3.745585 2.136165 3.05 Down 20323517_R chr9:20313342-20323517_R Heat shock protein 4, mRNA (cDNA clone 9.24329 7.634935 3.05 Down NM_008300 MGC:5961 IMAGE:3494648) AHNAK nucleoprotein (desmoyokin), mRNA -1.112455 -2.718165 3.04 Down A_55_P2162797 (cDNA clone IMAGE:4977508) chr7:88668948- -1.602745 -3.20705 3.04 Down 88678046_F chr7:88668948-88678046_F Sodium channel, voltage-gated, type III, alpha -1.13725 0.46791 3.04 Up NM_018732 (Scn3a), mRNA Synapsin I, mRNA (cDNA clone MGC:35985 2.901325 1.29722 3.04 Down NM_013680 IMAGE:5368098) Hepatitis B virus x interacting protein, mRNA 7.82214 6.219085 3.04 Down NM_026774 (cDNA clone MGC:41446 IMAGE:1513442) -2.669655 -1.06856 3.03 Up NM_001177521 Gm15308 -1.874545 -0.27416 3.03 Up NM_013794 Lectin-related NK cell receptor Ly49P Zinc finger protein 39, mRNA (cDNA clone -0.94522 -2.54294 3.03 Down NM_011758 IMAGE:4016059) Speedy homolog A (Xenopus laevis), mRNA (cDNA -0.582245 -2.180195 3.03 Down NM_029254 clone MGC:182851 IMAGE:9087465) 0.402685 -1.19605 3.03 Down NM_021436 Tomoregulin-1 (M7365) (TR-1 gene) 4.387675 2.789315 3.03 Down A_55_P2050408 PB-Cadherin Ribosomal protein S6 kinase, polypeptide 5 2.96398 4.561855 3.03 Up NM_153587 (Rps6ka5), mRNA A disintegrin and metallopeptidase domain 8, mRNA 6.55824 8.150885 3.02 Up NM_007403 (cDNA clone MGC:36123 IMAGE:5324943) SH3 domain and tetratricopeptide repeats 1, mRNA -0.9902 0.59995 3.01 Up NM_194344 (cDNA clone IMAGE:3490511) Benzodiazapine receptor associated protein 1, 5.07714 6.667785 3.01 Up NM_172449 mRNA (cDNA clone IMAGE:6400807) 5.89039 4.301635 3.01 Down NM_010706 Galectin-4 (Lgals4) 5.99809 4.40646 3.01 Down NM_001166494 Zpbp2 0.37289 -1.21094 3 Down NM_001162864 Ttbk1 Ecto-NOX disulfide-thiol exchanger 1, mRNA -1.201935 0.378365 2.99 Up A_55_P1978920 (cDNA clone MGC:62454 IMAGE:5703279) Tetraspanin 9, mRNA (cDNA clone 1.247005 2.825125 2.99 Up NM_175414 IMAGE:4219727) -1.47869 -3.05218 2.98 Down A_55_P2096067 Brown fat inducible thioesterase 2 Predicted gene, OTTMUSG00000016694 -3.03872 -1.46259 2.98 Up NM_001099326 (OTTMUSG00000016694), mRNA 3.544965 1.970155 2.98 Down NM_009826 Rb1cc1 mRNA for transcription factor UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (Galnt9), 4.0841 2.508655 2.98 Down NM_198306 transcript variant B, mRNA ENSMUST00000 POZ (BTB) and AT hook containing zinc finger 1, 9.48964 7.914185 2.98 Down 076314 mRNA (cDNA clone IMAGE:5029670) 1.855085 0.28225 2.97 Down NM_001081084 Cubilin Cysteine-rich secretory protein LCCL domain containing 2, mRNA (cDNA clone MGC:116029 6.63989 5.069635 2.97 Down NM_030209 IMAGE:30653388) -1.639015 -3.205555 2.96 Down NAP113893-1 Strain ILS synaptosomal associated protein 25 5.45814 3.89491 2.96 Down XM_973659 LOC674321 6.23104 4.6673 2.96 Down BC086781 S-adenosylhomocysteine hydrolase (Ahcy), mRNA ENSMUST00000 4.45344 2.88682 2.96 Down 109418 Intelectin 1 (galactofuranose binding) (Itln1), mRNA Serine/threonine/tyrosine interaction protein, mRNA 3.728335 2.16304 2.96 Down NM_019637 (cDNA clone MGC:47151 IMAGE:5012303) 3.077955 1.51244 2.96 Down NM_001199265 Epb4.1l2 chr12:110870903 -3.136785 -1.57725 2.95 Up -110891628_R chr12:110870903-110891628_R ENSMUST00000 -1.42738 -2.990145 2.95 Down 111750 Predicted gene, EG231885 (EG231885), mRNA chr1:88187397- -0.60793 -2.169375 2.95 Down 88187862_R chr1:88187397-88187862_R Glycoprotein (transmembrane) nmb, mRNA (cDNA 0.618525 2.1814 2.95 Up NM_053110 clone MGC:31121 IMAGE:4164706) ENSMUST00000 Zinc finger protein 120, mRNA (cDNA clone 3.23055 1.66829 2.95 Down 072014 IMAGE:4222737) chr10:62262341- -1.287935 -2.843015 2.94 Down 62271961_F chr10:62262341-62271961_F PREDICTED: Mus musculus hypothetical protein 0.692195 -0.86118 2.94 Down CF550758 LOC100040571 (LOC100040571), mRNA Chondroitin sulfate N- acetylgalactosaminyltransferase 2 (Csgalnact2), 3.64913 2.095285 2.94 Down NM_030165 mRNA Ladinin, mRNA (cDNA clone MGC:37195 -0.372675 1.17903 2.93 Up NM_133664 IMAGE:4954891) 3.057265 4.60915 2.93 Up NM_020002 REC8 homolog (yeast) (Rec8), mRNA 4.01663 2.472025 2.92 Down NM_009547 Zinc finger protein 161 (Zfp161), mRNA Nuclear casein kinase and cyclin-dependent kinase 6.15344 4.609425 2.92 Down NM_175294 substrate 1 (Nucks1), transcript variant 2, mRNA -1.509335 -3.04904 2.91 Down A_55_P2062886 A_55_P2062886 Killer cell lectin-like receptor subfamily A, member 3.89319 5.436285 2.91 Up NM_053152 22 (Klra22), mRNA 8.00204 6.458785 2.91 Down NM_025429 EIA (Serpinb1) Vesicle transport through interaction with t-SNAREs 1B homolog, mRNA (cDNA clone MGC:13826 8.02019 6.48146 2.91 Down NM_016800 IMAGE:4220215) 6.56749 5.025515 2.91 Down NM_009537 YY1 transcription factor (Yy1), mRNA Transmembrane and coiled coil domains 3, mRNA 3.59762 2.057535 2.91 Down NM_172051 (cDNA clone IMAGE:3989183) ENSMUST00000 12.08549 10.545835 2.91 Down 090257 Gm8225 PREDICTED: Mus musculus RIKEN cDNA 2410003L11 gene, transcript variant 2 -1.324225 -2.86213 2.9 Down AK010368 (2410003L11Rik), mRNA CUE domain containing 1, mRNA (cDNA clone 2.029815 0.49267 2.9 Down NM_198013 MGC:32430 IMAGE:5041450) Killer cell lectin-like receptor subfamily A, member 1.717255 3.254035 2.9 Up NM_024470 12 (Klra12), mRNA RIKEN cDNA A530057A03 gene 0.58584 2.120255 2.9 Up NM_001081089 (A530057A03Rik), mRNA 2,4-dienoyl CoA reductase 1, mitochondrial (Decr1), 5.96879 4.431715 2.9 Down NAP062849-1 nuclear gene encoding mitochondrial protein, mRNA Killer cell lectin-like receptor subfamily A, member 1.147905 2.679525 2.89 Up NM_024470 12 (Klra12), mRNA 3.609655 5.140735 2.89 Up NM_146187 Free fatty acid receptor 2 (Ffar2), mRNA Cytochrome P450, family 1, subfamily b, 2.703215 1.174515 2.89 Down NM_009994 polypeptide 1 (Cyp1b1), mRNA Synaptotagmin XI, mRNA (cDNA clone 6.00449 4.478535 2.88 Down NM_018804 MGC:32353 IMAGE:5030173) C-type lectin domain family 18, member A -1.61001 -3.131115 2.87 Down A_55_P2167549 (Clec18a), mRNA chr2:119412770- -0.531345 -2.05315 2.87 Down 119435110_R chr2:119412770-119435110_R chr4:94742359- -1.85611 -0.33701 2.87 Up 94822969_F chr4:94742359-94822969_F chr2:129416848- -2.18857 -0.66702 2.87 Up 129417413_R chr2:129416848-129417413_R chr17:8719950- -2.42725 -0.91042 2.86 Up 8783850_R chr17:8719950-8783850_R Heme oxygenase (decycling) 2, mRNA (cDNA 4.66123 3.146295 2.86 Down NM_010443 clone MGC:5802 IMAGE:3484259) 2.772515 1.25428 2.86 Down NM_028138 Thumpd2 8.53819 7.024335 2.86 Down NM_026618 Coiled-coil domain containing 56 (Ccdc56), mRNA Lectin, galactoside-binding, soluble, 3 binding 5.70734 4.19288 2.86 Down A_55_P2179448 protein (Lgals3bp), mRNA -0.76367 -2.2765 2.85 Down NM_001038697 Predicted gene, EG434729 (EG434729), mRNA -2.48446 -0.97519 2.85 Up TC1683167 TC1683167 Killer cell lectin-like receptor subfamily A, member 2.725565 4.23742 2.85 Up NM_001110323 12 (Klra12), mRNA RIKEN cDNA D230014K01 gene, mRNA (cDNA 4.53524 3.02284 2.85 Down NM_172573 clone IMAGE:40097898) 5.53709 4.02485 2.85 Down NM_146208 Putative DNA glycosylase chr6:129151512- 5.31909 3.81115 2.84 Down 129208737_R chr6:129151512-129208737_R 3.79768 2.29002 2.84 Down NM_001177668 Spna2 6.93574 5.427355 2.84 Down A_55_P2064171 Transcribed locus chr9:96964067- -1.707035 -3.209765 2.83 Down 96973567_F chr9:96964067-96973567_F -1.592685 -3.0917 2.83 Down AK082156 Transcribed locus chr13:99469411- -1.755265 -3.25764 2.83 Down 99469882_F chr13:99469411-99469882_F chr12:73860757- -1.02856 -2.531065 2.83 Down 73862034_R chr12:73860757-73862034_R 0.63558 2.13642 2.83 Up NM_010650 Killer cell lectin-like receptor subfamily A, member 21 (Klra21), mRNA 0.397865 -1.10365 2.83 Down A_55_P2120650 A_55_P2120650 Cell division cycle 2-like 1, mRNA (cDNA clone 7.70419 6.20235 2.83 Down NM_007661 IMAGE:4194992) ENSMUST00000 Lysophosphatidylcholine acyltransferase 1 (Lpcat1), 3.54876 2.04689 2.83 Down 103593 mRNA 7.09534 5.596885 2.83 Down NM_001242388 9830147E19Rik chr17:47022781- -0.72244 -2.216835 2.82 Down 47023428_F chr17:47022781-47023428_F chr6:35441848- -1.73737 -3.233855 2.82 Down 35450830_R chr6:35441848-35450830_R chr2:3703146- -1.218215 -2.71497 2.82 Down 3703715_F chr2:3703146-3703715_F chr19:53517903- 0.883735 2.37831 2.82 Up 53540753_R chr19:53517903-53540753_R RNA and export factor binding protein 2 (Refbp2), 4.73164 3.234815 2.82 Down NM_019484 mRNA -1.88038 -0.39146 2.81 Up NM_011866 CAMP/cGMP phosphodiesterase (Pde10a) ENSMUST00000 -2.150835 -0.65999 2.81 Up 108846 Galnt10 0.76778 2.25953 2.81 Up NM_010736 Lymphotoxin B receptor (Ltbr), mRNA ENSMUST00000 -1.002735 -2.48631 2.8 Down 058338 Brain cDNA, clone MNCb-3966 LIM domain only 2 (Lmo2), transcript variant 1, -0.9676 -2.45298 2.8 Down NM_008505 mRNA -2.39416 -0.909585 2.8 Up NM_138682 Leucine rich repeat containing 4 (Lrrc4), mRNA Amyloid beta (A4) precursor-like protein 1, mRNA 5.77309 4.285305 2.8 Down NM_007467 (cDNA clone MGC:25658 IMAGE:4481838) ENSMUST00000 Microtubule-associated protein 2 (Mtap2), transcript -2.399315 -0.91987 2.79 Up 114013 variant 2, mRNA chr19:59498190- -0.865665 -2.34756 2.79 Down 59531390_F chr19:59498190-59531390_F Vacuolar proton-translocating ATPase 100 kDa 4.62794 3.147125 2.79 Down NM_011596 subunit isoform a2 chr17:6806500- -0.710355 -2.182995 2.78 Down 6861042_R chr17:6806500-6861042_R Transcribed locus, strongly similar to XP_001477946.1 PREDICTED: hypothetical protein -2.24292 -0.76903 2.78 Up AK007120 [Mus musculus] Glial cell line derived neurotrophic factor family -1.14538 0.32764 2.78 Up NM_008115 receptor alpha 2 (Gfra2), mRNA ENSMUST00000 CCR4-NOT transcription complex, subunit 6, 0.26192 -1.21149 2.78 Down 106768 mRNA (cDNA clone IMAGE:5343685) Ubiquitin D, mRNA (cDNA clone MGC:41063 4.544365 3.06716 2.78 Down NM_023137 IMAGE:1347593) MAS-related GPR, member B2, mRNA (cDNA -2.58158 -1.113525 2.77 Up NM_175531 clone MGC:130391 IMAGE:40057816) -2.27367 -0.80417 2.77 Up NM_001104578 Vomeronasal 2, receptor 113 (Vmn2r113), mRNA T-cell receptor gamma, constant region, mRNA 2.338425 3.808645 2.77 Up AK038325 (cDNA clone MGC:6230 IMAGE:3495512) -2.723775 -1.266645 2.75 Up NM_146353 Olfactory receptor 706 (Olfr706), mRNA Enabled homolog (Drosophila) (Enah), transcript -0.70422 -2.164315 2.75 Down AK031940 variant 1, mRNA -1.035055 0.4237 2.75 Up A_55_P2095171 A_55_P2095171 0.309935 1.771435 2.75 Up NR_002858 Gm4956 Histone cluster 1, H2bc, mRNA (cDNA clone 5.270665 3.809215 2.75 Down NM_023422 MGC:30336 IMAGE:3993954) Aldo-keto reductase family 1, member C18, mRNA 5.27231 6.732885 2.75 Up NM_134066 (cDNA clone MGC:25953 IMAGE:4238589) Leucine-rich repeat kinase 2, mRNA (cDNA clone 2.24878 0.79041 2.75 Down NM_025730 IMAGE:4242403) 3.184485 1.72554 2.75 Down NM_008496 Beta-galactoside-binding protein galectin-7 (Lgals7) chr4:136856064- 9.52829 8.066785 2.75 Down 136877219_R chr4:136856064-136877219_R -1.92848 -0.473765 2.74 Up NM_001081046 EF-hand calcium binding domain 3 (Efcab3), mRNA -1.937015 -0.4813 2.74 Up NM_010374 Granzyme F (Gzmf), mRNA chr4:135896689- -2.121595 -0.66686 2.74 Up 135918414_R chr4:135896689-135918414_R chr2:129416848- -0.93854 -2.39474 2.74 Down 129417413_R chr2:129416848-129417413_R chr14:27176652- -1.571115 -3.02092 2.73 Down 27227602_F chr14:27176652-27227602_F -1.977355 -0.52716 2.73 Up NM_009292 Stimulated by retinoic acid gene 8 (Stra8), mRNA 0.3922 1.842095 2.73 Up NM_025288 Stefin A3 (Stfa3), mRNA ENSMUST00000 4.42994 5.876435 2.73 Up 103558 Myotubularin related protein 1 (Mtmr1), mRNA CAP-GLY domain containing linker protein 3, mRNA (cDNA clone MGC:170038 4.2941 2.84747 2.73 Down NM_001081114 IMAGE:8861433) 6.70399 5.25699 2.73 Down NM_001161338 Sh3bp5l ENSMUST00000 Akirin 1, mRNA (cDNA clone MGC:7743 -1.210485 -2.65626 2.72 Down 064334 IMAGE:3498569) -2.237195 -0.79401 2.72 Up A_55_P1987336 A_55_P1987336 PWWP domain containing 2B (Pwwp2b), transcript 4.59744 3.15522 2.72 Down NM_001098636 variant 1, mRNA Transmembrane protein 206, mRNA (cDNA clone 5.62624 4.18268 2.72 Down NM_025864 MGC:35701 IMAGE:4948749) chr4:149383134- -1.03449 -2.47433 2.71 Down 149451259_R chr4:149383134-149451259_R chr1:63163023- -0.851345 -2.28911 2.71 Down 63180223_R chr1:63163023-63180223_R Killer cell lectin-like receptor subfamily A, member 1.620585 3.059435 2.71 Up NM_014194 12 (Klra12), mRNA 4.059145 2.622455 2.71 Down NM_053207 EGL nine homolog 1 (C. elegans) (Egln1), mRNA 0.998065 -0.43839 2.71 Down ENSMUST00000 Leucine rich repeat and coiled-coil domain 150194 containing 1, mRNA (cDNA clone MGC:170362 IMAGE:8861757) chr13:64381475- -0.685935 -2.117455 2.7 Down 64415350_F chr13:64381475-64415350_F Icos ligand, mRNA (cDNA clone MGC:35971 0.78869 2.2199 2.7 Up NM_015790 IMAGE:4217333) chr1:115829055- -1.347635 -2.774335 2.69 Down 115854155_F chr1:115829055-115854155_F Sodium channel, voltage-gated, type I, beta, mRNA 2.702845 1.27286 2.69 Down NM_011322 (cDNA clone MGC:18389 IMAGE:3672893) 11.41334 9.984485 2.69 Down A_55_P2012615 A_55_P2012615 UDP glucuronosyltransferase 1 family, polypeptide A6B, mRNA (cDNA clone MGC:36247 -1.52052 -2.942355 2.68 Down NM_145079 IMAGE:5050488) chr19:61226425- -1.265055 -2.68645 2.68 Down 61270975_R chr19:61226425-61270975_R -2.62396 -1.209035 2.67 Up NM_146405 Olfactory receptor 228 (Olfr228), mRNA Proteasome (prosome, macropain) 26S subunit, non- ATPase, 4, mRNA (cDNA clone MGC:6683 -1.64412 -3.05931 2.67 Down NAP066544-1 IMAGE:3581937) chr7:69005291- -1.6152 -3.03412 2.67 Down 69007813_R chr7:69005291-69007813_R -0.88878 -2.30304 2.67 Down NM_001166636 Gm4312 0.443905 -0.974775 2.67 Down NM_001111317 CDNA sequence BC048609 (BC048609), mRNA 5.37169 3.952215 2.67 Down NM_021360 Neuralized 1 chr9:118060025- -1.71974 -3.13279 2.66 Down 118085050_R chr9:118060025-118085050_R -1.80953 -0.406135 2.65 Up NM_001081441 WD repeat domain 86 (Wdr86), mRNA 0.90384 2.312085 2.65 Up NM_001082542 Predicted gene, EG408196 (EG408196), mRNA ARP5 actin-related protein 5 homolog (yeast) 6.11904 4.71103 2.65 Down NM_175419 (Actr5), mRNA Cysteine-rich secretory protein LCCL domain containing 2, mRNA (cDNA clone MGC:116029 7.90734 6.503485 2.65 Down NM_030209 IMAGE:30653388) Spermatogenesis associated 3 (Spata3), transcript -1.675325 -3.077455 2.64 Down NM_027029 variant 1, mRNA chr12:116850878 -1.630395 -3.03308 2.64 Down -116855932_R chr12:116850878-116855932_R -0.94445 0.4542 2.64 Up NM_007895 Eosinophil-associated ribonuclease EAR2 (Ear2) -2.21778 -0.81894 2.64 Up NM_009903 Claudin 4 (Cldn4), mRNA chr5:15146475- -2.50316 -1.103475 2.64 Up 15170100_F chr5:15146475-15170100_F 2.457845 1.05818 2.64 Down NM_010821 MPS1 gene and mRNA, 3end Intermediate filament family orphan 1 (Iffo1), 4.408145 3.00929 2.64 Down NM_001039669 transcript variant 1, mRNA -1.13197 0.264595 2.63 Up NM_001204153 C1qtnf6 PREDICTED: Mus musculus similar to KIAA1731 4.617575 3.22088 2.63 Down NM_176976 protein (LOC100040375), mRNA 10.33579 8.941485 2.63 Down NM_001195717 Gm12034 7.53049 6.135335 2.63 Down A_55_P2055137 MKIAA1613 protein -1.91426 -0.522615 2.62 Up A_55_P2132128 A_55_P2132128 ENSMUST00000 NLR family, pyrin domain containing 4C (Nlrp4c), 0.563845 1.954275 2.62 Up 105884 mRNA Ubiquitin related modifier 1 homolog (S. cerevisiae) 6.68499 5.29807 2.62 Down NM_026615 (Urm1), mRNA Clathrin, heavy polypeptide (Hc), mRNA (cDNA 5.02914 3.639045 2.62 Down NM_001003908 clone IMAGE:5369419) -2.798655 -1.41505 2.61 Up NM_146335 Olfactory receptor 19 (Olfr19), mRNA Synaptotagmin-like 2 (Sytl2), transcript variant 3, 0.364685 1.74873 2.61 Up NM_001040087 mRNA Ureidopropionase, beta, mRNA (cDNA clone 2.204535 0.81978 2.61 Down NM_133995 IMAGE:4974180) 10.55489 9.170935 2.61 Down NR_036654 Gm6525 Neuropilin 2, mRNA (cDNA clone 5.05249 3.667655 2.61 Down NM_001077403 IMAGE:3968483) Killer cell lectin-like receptor subfamily A (Klra- -2.32223 -0.94249 2.6 Up AY860976 ps1) pseudogene mRNA, complete sequence Taste receptor, type 2, member 143, mRNA (cDNA -1.41895 -2.797705 2.6 Down NM_001001452 clone MGC:165170 IMAGE:40050382) chr1:185808525- -2.49257 -1.11574 2.6 Up 185826139_F chr1:185808525-185826139_F Nudix (nucleoside diphosphate linked moiety X)- ENSMUST00000 type motif 5, mRNA (cDNA clone MGC:8023 -0.18645 -1.56539 2.6 Down 108303 IMAGE:3586340) Phospholipase C, delta 4 (Plcd4), transcript variant 2.68158 1.300865 2.6 Down NM_148937 2, mRNA 1.813155 3.191265 2.6 Up NM_198297 T cell receptor interacting molecule (Trim gene) 4.92809 3.549145 2.6 Down AK038031 Transcribed locus 4.73829 6.114985 2.6 Up NM_008147 Glycoprotein 49 A (Gp49a), mRNA chr8:119732348- 4.050775 2.674915 2.6 Down 119749198_F chr8:119732348-119749198_F Serine hydrolase-like, mRNA (cDNA clone 6.61464 5.236565 2.6 Down NM_023475 IMAGE:5134679) -1.307645 -2.679835 2.59 Down NM_153778 Atonal homolog 8 (Drosophila) (Atoh8), mRNA WW domain containing E3 ubiquitin protein ligase -1.65147 -3.02538 2.59 Down NM_177327 1, mRNA (cDNA clone IMAGE:5343337) chr17:22815742- -1.64756 -0.27682 2.59 Up 22828592_R chr17:22815742-22828592_R RNA binding protein with multiple splicing 2 3.51244 2.14174 2.59 Down NM_028030 (Rbpms2), mRNA -1.166875 -2.53668 2.58 Down NM_008148 Glycoprotein 5 (platelet) (Gp5), mRNA chr3:57416618- -1.54718 -2.91672 2.58 Down 57429679_R chr3:57416618-57429679_R chr2:151343784- -1.39601 -2.76301 2.58 Down 151344246_F chr2:151343784-151344246_F Arylsulfatase i, mRNA (cDNA clone -1.82363 -3.192775 2.58 Down NM_001038499 IMAGE:3991175) Fibrinogen, gamma polypeptide, mRNA (cDNA -1.47782 -2.8469 2.58 Down NM_133862 clone MGC:29970 IMAGE:5123696) Frizzled homolog 4 (Drosophila), mRNA (cDNA -0.821495 -2.1897 2.58 Down NM_008055 clone MGC:18403 IMAGE:4238940) Expressed sequence AU022252, mRNA (cDNA 3.653565 2.284135 2.58 Down NM_001012400 clone IMAGE:5367768) Cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase), mRNA (cDNA clone 4.57534 3.21052 2.58 Down NM_009874 MGC:6069 IMAGE:3585145) Kelch-like 9 (Drosophila), mRNA (cDNA clone 7.04074 5.67474 2.58 Down NM_172871 MGC:106634 IMAGE:6811241) -2.101 -0.74031 2.57 Up NM_023816 Ankyrin repeat domain 36 (Ankrd36), mRNA -1.03682 -2.39594 2.57 Down NM_001190466 Dact1 Leucine-rich repeat-containing G protein-coupled 1.796445 0.432225 2.57 Down NM_172671 receptor 4, mRNA (cDNA clone IMAGE:5065281) 1.568705 0.207685 2.57 Down AK082690 Transcribed locus CCCTC-binding factor (zinc finger protein)-like, mRNA (cDNA clone MGC:183939 -2.520615 -1.1641 2.56 Up NM_001081387 IMAGE:9087939) chr18:84735774- -1.585185 -2.940075 2.56 Down 84760824_F chr18:84735774-84760824_F Ribonuclease, RNase A family, 12 (non-active), mRNA (cDNA clone MGC:175903 -1.170305 -2.528975 2.56 Down NM_001011875 IMAGE:40131319) Glypican 3, mRNA (cDNA clone MGC:35964 -1.48501 -2.8411 2.56 Down NM_016697 IMAGE:4973409) Opsin 4 (melanopsin) (Opn4), transcript variant 1, -1.05986 -2.41349 2.56 Down A_55_P2061899 mRNA Serine (or cysteine) peptidase inhibitor, clade I, member 1, mRNA (cDNA clone MGC:6413 -0.38189 -1.73723 2.56 Down NM_009250 IMAGE:3588856) chr16:59556175- -0.143595 -1.50173 2.56 Down 59603176_R chr16:59556175-59603176_R chr1:138473514- -2.305875 -0.95251 2.56 Up 138476054_R chr1:138473514-138476054_R chr3:51990494- -1.405885 -2.76353 2.56 Down 51991875_F chr3:51990494-51991875_F -0.37656 -1.734965 2.56 Down NM_001164329 Gm6904 Glucan (1,4-alpha-), branching enzyme 1 (Gbe1), 7.90194 6.546795 2.56 Down NM_028803 mRNA Transcribed locus, weakly similar to XP_001474640.1 PREDICTED: similar to 4.138425 2.78323 2.56 Down BB517238 hCG1807877 [Mus musculus] 5.02889 3.671805 2.56 Down NM_027107 2310004N24Rik Poly(rC) binding protein 1, mRNA (cDNA clone 10.17204 8.815685 2.56 Down NM_011865 MGC:5645 IMAGE:3588737) 8.72649 10.080585 2.56 Up NM_013542 Granzyme B, mRNA (cDNA clone MGC:6257 IMAGE:3592898) 0.99129 2.34286 2.55 Up NM_133977 Transferrin (Trf), mRNA Gene regulated by estrogen in breast cancer protein 6.08394 4.735695 2.55 Down A_55_P2114785 (Greb1), mRNA ARP1 actin-related protein 1 homolog A, centractin alpha (yeast), mRNA (cDNA clone MGC:5816 8.19739 6.848335 2.55 Down NM_016860 IMAGE:3599656) chr8:13537677- -1.55594 -2.902095 2.54 Down 13547026_R chr8:13537677-13547026_R chr8:74333475- -2.45224 -1.109325 2.54 Up 74384150_F chr8:74333475-74384150_F chr5:15176325- -2.724155 -1.37988 2.54 Up 15223375_R chr5:15176325-15223375_R chr13:83867711- -2.0683 -0.72222 2.54 Up 83878140_F chr13:83867711-83878140_F 3.49521 2.149295 2.54 Down NM_172146 Ppat 0.71319 -0.629495 2.54 Down NM_001004154 Ras-related GTP binding B (Rragb), mRNA RIKEN cDNA 4930566A11 gene, mRNA (cDNA 4.70814 3.362845 2.54 Down NM_029468 clone IMAGE:5323197) chr11:18479852- -1.70347 -0.36404 2.53 Up 18485704_R chr11:18479852-18485704_R -1.99096 -0.6591 2.52 Up NM_146628 Olfactory receptor 344 (Olfr344), mRNA -2.65368 -1.318305 2.52 Up AI851680 Transcribed locus -0.264885 -1.598495 2.52 Down NM_013462 Beta-3b adrenergic receptor splice variant (B3bar) RIKEN cDNA 5830417I10 gene, mRNA (cDNA -2.494885 -1.16041 2.52 Up AK051305 clone IMAGE:5012813) EF-9 polyadenylation variant II mRNA, complete 3.01413 4.346875 2.52 Up NM_010959 cds, alternatively spliced RIKEN cDNA 2900011O08 gene (2900011O08Rik), 1.964515 0.63031 2.52 Down NM_144518 mRNA chr16:94521875- 3.59179 2.256815 2.52 Down 94545750_R chr16:94521875-94545750_R ENSMUST00000 PREDICTED: Mus musculus similar to T-cell -2.553995 -1.226375 2.51 Up 103555 receptor alpha (LOC100043204), mRNA Inositol polyphosphate 5-phosphatase J, mRNA -1.804865 -0.47521 2.51 Up NM_172439 (cDNA clone MGC:150005 IMAGE:40096940) -0.835535 -2.16583 2.51 Down A_55_P2042368 MKIAA0084 protein chr8:90000619- -1.02393 0.305705 2.51 Up 90061169_F chr8:90000619-90061169_F 2.78912 1.461765 2.51 Down NM_153568 Leucine rich repeat containing 66 (Lrrc66), mRNA 6.85624 5.531135 2.51 Down NM_153599 Cyclin-dependent kinase 8 (Cdk8), mRNA Guanine nucleotide binding protein, alpha transducing 3, mRNA (cDNA clone MGC:182197 -2.186665 -0.86464 2.5 Up A_55_P2150013 IMAGE:9056091) chr15:83266264- -1.279025 -2.60236 2.5 Down 83294664_F chr15:83266264-83294664_F Leukocyte immunoglobulin-like receptor, subfamily 4.83324 6.157035 2.5 Up NM_013532 B, member 4, mRNA (cDNA clone MGC:6091 IMAGE:3585404) ENSMUST00000 3.93345 2.612065 2.5 Down 105338 Mknk2 Mitochondrial ribosomal protein L39, mRNA 6.26214 4.940635 2.5 Down NM_017404 (cDNA clone MGC:27731 IMAGE:2645316) chr13:41337973- -1.586705 -2.899985 2.49 Down 41379821_R chr13:41337973-41379821_R RIKEN cDNA 1700110M21 gene -2.323125 -1.006765 2.49 Up NM_029680 (1700110M21Rik), mRNA C-type lectin domain family 7, member a, mRNA 0.77077 2.085615 2.49 Up NM_020008 (cDNA clone MGC:29217 IMAGE:5036647) ENSMUST00000 3.926485 2.610465 2.49 Down 035278 3-Mar -1.553095 -2.86303 2.48 Down NM_146279 Olfactory receptor 960 (Olfr960), mRNA -0.865385 -2.176825 2.48 Down AK006259 Transcribed locus FMS-like tyrosine kinase 1, mRNA (cDNA clone -0.27778 1.033455 2.48 Up NM_010228 MGC:36074 IMAGE:5368921) -1.762885 -0.45355 2.48 Up A_55_P2025630 Transcribed locus Solute carrier family 26, member 7 (Slc26a7), -2.792245 -1.481675 2.48 Up NM_145947 mRNA Caspase 4, apoptosis-related cysteine peptidase 7.12664 5.814385 2.48 Down NM_007609 (Casp4), mRNA 6.62519 5.312685 2.48 Down NM_029274 WW domain binding protein 7 (Wbp7), mRNA chr3:38320928- 3.808605 2.49818 2.48 Down 38341869_R chr3:38320928-38341869_R -1.25563 -2.55821 2.47 Down TC1716662 TC1716662 chr16:59557120- -1.386115 -2.687825 2.47 Down 59602070_R chr16:59557120-59602070_R ENSMUST00000 -2.10858 -0.80186 2.47 Up 098260 Olfactory receptor 1183 (Olfr1183), mRNA RIKEN cDNA 6330512M04 gene, mRNA (cDNA -0.548235 0.758455 2.47 Up BC049666 clone MGC:58491 IMAGE:6534368) Dynein cytoplasmic 2 light intermediate chain 1, 0.75377 -0.548525 2.47 Down NM_172256 mRNA (cDNA clone MGC:7211 IMAGE:3482503) Muscleblind-like 1 (Drosophila), mRNA (cDNA 7.80384 6.496485 2.47 Down NM_020007 clone IMAGE:1511990) chr4:147105275- -1.42978 -2.728155 2.46 Down 147171025_R chr4:147105275-147171025_R POU domain, class 4, transcription factor 2 -2.195965 -0.896975 2.46 Up NM_138944 (Pou4f2), mRNA G protein-coupled receptor 141, mRNA (cDNA -0.839395 0.45679 2.46 Up NM_181754 clone MGC:159288 IMAGE:40130100) Thromboxane A synthase 1, platelet, mRNA (cDNA 0.901655 2.20319 2.46 Up NM_011539 clone MGC:32210 IMAGE:5007629) Serine (or cysteine) peptidase inhibitor, clade I, member 1, mRNA (cDNA clone MGC:6413 0.758675 -0.537565 2.46 Down NM_009250 IMAGE:3588856) Receptor (calcitonin) activity modifying protein 1, 0.32072 -0.971225 2.45 Down NM_016894 mRNA (cDNA clone IMAGE:5323866) 2.57498 3.86509 2.45 Up NM_001033324 PLZF gene 8.29339 7.002885 2.45 Down NM_133726 Suppression of tumorigenicity 13 (St13), mRNA RIKEN cDNA 2210408I21 gene (2210408I21Rik), -1.741205 -3.025745 2.44 Down NM_001081353 transcript variant 1, mRNA Fibroblast growth factor 1, mRNA (cDNA clone -1.523085 -2.809905 2.44 Down NM_010197 MGC:46904 IMAGE:5137246) -1.978615 -0.693585 2.44 Up AK044339 Esrrb chr8:18895366- -1.166465 0.12208 2.44 Up 18925423_R chr8:18895366-18925423_R 1.70623 2.99374 2.44 Up NM_019577 Eotaxin-2 (Scya24) INAP mRNA for IL-1 inducible nuclear ankyrin- 3.711125 2.4261 2.44 Down NM_030612 repeat protein Eukaryotic translation initiation factor 5, mRNA 7.97934 6.692185 2.44 Down NM_173363 (cDNA clone MGC:36374 IMAGE:4984912) chr5:144519149- -0.710355 -1.98994 2.43 Down 144527843_F chr5:144519149-144527843_F -1.91223 -0.629155 2.43 Up AK132990 Transcribed locus 1.728455 0.448295 2.43 Down NM_001190371 Ankrd29 Polypyrimidine tract binding protein 2, mRNA 3.36935 2.087175 2.43 Down NM_019550 (cDNA clone MGC:11671 IMAGE:3709255) Kallikrein B, plasma 1, mRNA (cDNA clone 3.301295 2.01798 2.43 Down NM_133969 MGC:36124 IMAGE:4972788) chr6:122725638- -1.363245 -2.63648 2.42 Down 122752828_R chr6:122725638-122752828_R chr16:59557120- -1.098235 -2.37075 2.42 Down 59602070_R chr16:59557120-59602070_R ENSMUST00000 -1.814805 -0.53907 2.42 Up 152691 MORN repeat containing 4 (Morn4), mRNA chr19:4991356- -1.2691 -2.544645 2.42 Down 4993113_R chr19:4991356-4993113_R -0.92245 -2.19608 2.42 Down NM_011564 Sex determining region of Chr Y (Sry), mRNA -2.769885 -1.493615 2.42 Up NM_144856 SLC22A7 mRNA for organic anion transporter 2 2.03155 0.756205 2.42 Down XR_035730 6030426L16Rik 4.96869 3.692925 2.42 Down NM_001135577 CDNA sequence BC024659 (BC024659), mRNA ENSMUST00000 -1.746235 -3.016415 2.41 Down 108743 Abnormal spindle (Asp) Cytochrome P450, family 2, subfamily u, -0.68859 -1.960175 2.41 Down NM_027816 polypeptide 1 (Cyp2u1), mRNA chrX:12755425- -1.47064 -2.739955 2.41 Down 12772575_R chrX:12755425-12772575_R chr19:53517903- 0.54747 1.81522 2.41 Up 53540753_F chr19:53517903-53540753_F chr4:35106125- 0.816255 -0.451105 2.41 Down 35127700_R chr4:35106125-35127700_R 5.37794 4.10942 2.41 Down NM_021360 Neuralized 1 3.355215 4.626875 2.41 Up NM_001039546 Mus musculus, clone IMAGE:4242613, mRNA 4.77279 3.501405 2.41 Down NM_001111076 Zinc finger protein 182 (Zfp182), transcript variant 2, mRNA -1.037075 -2.30055 2.4 Down NM_199060 Clone L4 variable group of 2-cell-stage gene family -2.880385 -1.61629 2.4 Up NM_001039889 Sperm motility kinase 3B (Smok3b), mRNA -1.994865 -0.730875 2.4 Up NM_146604 Olfactory receptor 716 (Olfr716), mRNA 2.34012 3.60559 2.4 Up NM_009892 Chitinase 3-like 3 (Chi3l3), mRNA 0.37771 1.63958 2.4 Up NM_019517 Beta-site APP-cleaving enzyme 2 (Bace2), mRNA 2.059575 0.795405 2.4 Down NM_145577 CDNA sequence BC023179 (BC023179), mRNA 3.398765 2.13795 2.4 Down NM_001177513 Gm7102 -1.064015 -2.323005 2.39 Down A_55_P2058528 A_55_P2058528 chr4:3149375- -1.89421 -3.152115 2.39 Down 3169700_R chr4:3149375-3169700_R -2.55679 -1.298175 2.39 Up NM_019568 IMAGE:442143 MIP2gamma Protein phosphatase 1, regulatory (inhibitor) subunit 1C, mRNA (cDNA clone MGC:163780 -2.44154 -1.183615 2.39 Up NM_172420 IMAGE:40130426) 1.75928 0.5035 2.39 Down NM_153098 CD109 antigen (Cd109), mRNA Leukocyte immunoglobulin-like receptor, subfamily B, member 4, mRNA (cDNA clone MGC:6091 8.74509 9.999335 2.39 Up NM_013532 IMAGE:3585404) Laminin gamma 3, mRNA (cDNA clone 5.14149 3.88247 2.39 Down NM_011836 IMAGE:3497518) chr17:79042382- -1.01491 -2.26442 2.38 Down 79051807_R chr17:79042382-79051807_R Leucine-rich repeat kinase 2, mRNA (cDNA clone 0.334975 -0.91586 2.38 Down NM_025730 IMAGE:4242403) chr5:14943275- 0.987675 2.241445 2.38 Up 14944205_F chr5:14943275-14944205_F Chemokine (C-X-C motif) receptor 6 (Cxcr6), 6.45159 7.701285 2.38 Up NM_030712 mRNA Solute carrier family 25, member 28 (Slc25a28), 7.14919 5.896785 2.38 Down NAP092468-001 mRNA Nuclear receptor coactivator 7, mRNA (cDNA clone 2.25001 0.996185 2.38 Down NM_172495 MGC:176111 IMAGE:9055762) Cathepsin S, mRNA (cDNA clone MGC:6643 8.14439 6.893585 2.38 Down NM_021281 IMAGE:3495719) 1.280095 0.03331 2.37 Down NM_001007573 Gene model 50, (NCBI) (Gm50), mRNA -2.021235 -0.782465 2.36 Up XR_104840 Gm15535 chr3:22184002- -2.7075 -1.466525 2.36 Up 22196752_R chr3:22184002-22196752_R -2.62752 -1.389555 2.36 Up NM_011667 Ubiquitin-activating enzyme E1 (Ube1y1) chr12:72103832- -0.93052 -2.16984 2.36 Down 72116875_F chr12:72103832-72116875_F Pleckstrin homology domain containing, family B (evectins) member 1, mRNA (cDNA clone 0.727375 -0.511325 2.36 Down A_55_P2123711 MGC:35994 IMAGE:5369461) Proteoglycan 4 (megakaryocyte stimulating factor, 2.90402 1.66586 2.36 Down NM_021400 articular superficial zone protein) (Prg4), transcript variant 1, mRNA -2.10169 -0.870275 2.35 Up NM_001199332 LOC100041550 chr11:33414450- -0.945165 -2.177155 2.35 Down 33450750_F chr11:33414450-33450750_F Sorting nexin 9, mRNA (cDNA clone MGC:6327 -1.77538 -0.54118 2.35 Up A_55_P1957865 IMAGE:3257422) -1.9269 -0.696325 2.35 Up NR_023846 Apeg3 NAD(P)H dehydrogenase, quinone 2, mRNA -1.623685 -0.39817 2.34 Up NM_020282 (cDNA clone MGC:41088 IMAGE:1225122) chr1:138570107- -2.44686 -1.22262 2.34 Up 138632310_R chr1:138570107-138632310_R PREDICTED: Mus musculus RIKEN cDNA 0.634375 -0.59453 2.34 Down AK021392 E130116L18 gene (E130116L18Rik), mRNA Purine-nucleoside phosphorylase 1, mRNA (cDNA 1.64768 0.41823 2.34 Down NM_001123371 clone MGC:6018 IMAGE:3600212) 1.216475 2.44226 2.34 Up NM_026594 Ribosomal protein L39-like (Rpl39l), mRNA ADP-ribosylation factor GTPase activating protein 3 3.358685 2.129475 2.34 Down NM_025445 (Arfgap3), mRNA Solute carrier family 33 (acetyl-CoA transporter), member 1, mRNA (cDNA clone MGC:6986 2.977525 1.753225 2.34 Down NM_015728 IMAGE:3154886) -0.84667 -2.065945 2.33 Down NM_008970 Parathyroid hormone-related protein (Pthlh gene) chr7:134779841- -1.70129 -2.921135 2.33 Down 134840591_R chr7:134779841-134840591_R Protocadherin gamma subfamily A, 1 (Pcdhga1), -2.768385 -1.547685 2.33 Up NM_033584 mRNA A disintegrin and metallopeptidase domain 8, mRNA -1.82306 -3.04419 2.33 Down A_55_P2025775 (cDNA clone MGC:36123 IMAGE:5324943) chr1:69555180- -2.22658 -1.008165 2.33 Up 69555559_R chr1:69555180-69555559_R -1.475485 -2.696095 2.33 Down NM_023249 Yippee-like 1 (Drosophila) (Ypel1), mRNA chr13:98635795- -1.393105 -0.17342 2.33 Up 98646617_R chr13:98635795-98646617_R Transcribed locus, strongly similar to XP_001471887.1 PREDICTED: hypothetical protein 3.6077 2.387035 2.33 Down AK049147 [Mus musculus] 3.15036 1.93153 2.33 Down XR_105883 2810468N07Rik Monooxygenase, DBH-like 1, mRNA (cDNA clone 2.355035 3.57714 2.33 Up NM_021509 IMAGE:3675929) 2.55965 1.339075 2.33 Down NM_133185 Rogdi homolog (Drosophila) (Rogdi), mRNA chr13:99870660- -2.19759 -0.981205 2.32 Up 99877535_F chr13:99870660-99877535_F chr4:56480568- -1.69758 -2.913225 2.32 Down 56658018_R chr4:56480568-56658018_R -2.719755 -1.505425 2.32 Up NR_030671 AW011738 Gap junction protein, alpha 6, mRNA (cDNA clone -1.248135 -2.45918 2.32 Down NM_001001496 MGC:143563 IMAGE:40090837) -2.531145 -1.31739 2.32 Up NR_002869 Gm5477 -2.48582 -1.27336 2.32 Up NM_201600 Myosin VB, mRNA (cDNA clone IMAGE:4207857) chr11:3539787- 4.95314 3.73926 2.32 Down 3548811_R chr11:3539787-3548811_R UDP glucuronosyltransferase 2 family, polypeptide ENSMUST00000 B5, mRNA (cDNA clone MGC:40638 11.11899 9.902385 2.32 Down 090257 IMAGE:5102040) Glycine receptor, alpha 2 subunit, mRNA (cDNA -2.458295 -1.248735 2.31 Up NM_183427 clone IMAGE:4527768) -1.686915 -2.893005 2.31 Down NM_001104624 Vomeronasal 2, receptor 13 (Vmn2r13), mRNA -1.835935 -3.0432 2.31 Down XM_205232 Gm715 chr8:24327427- -1.104005 -2.312 2.31 Down 24332452_R chr8:24327427-24332452_R ENSMUST00000 Tubulin, gamma complex associated protein 4 -1.890085 -0.68098 2.31 Up 051989 (Tubgcp4), mRNA chr4:55593675- -1.931065 -0.723295 2.31 Up 55629225_R chr4:55593675-55629225_R -2.19309 -0.985475 2.31 Up TC1619416 TC1619416 ATPase, class I, type 8B, member 4, mRNA (cDNA 0.96347 2.168455 2.31 Up NM_001080944 clone IMAGE:40142776) 3.030325 1.82168 2.31 Down EU616813 EU616813 Transcribed locus, strongly similar to XP_987815.2 PREDICTED: similar to CDNA sequence -1.708795 -2.90804 2.3 Down AK076616 BC061237 [Mus musculus] Zinc finger protein 385C, mRNA (cDNA clone -1.23812 -2.440545 2.3 Down NM_177790 MGC:144840 IMAGE:40106534) chr6:47595238- 2.7635 1.563285 2.3 Down 47601893_F chr6:47595238-47601893_F Guanylate kinase 1, mRNA (cDNA clone 6.12484 4.92088 2.3 Down NM_008193 MGC:25313 IMAGE:4485215) 5.42584 4.22593 2.3 Down NM_001172055 Bdh2 chr9:118060025- -1.784515 -0.5861 2.29 Up 118085050_F chr9:118060025-118085050_F Exophilin 5, mRNA (cDNA clone MGC:141574 -1.34752 -2.54025 2.29 Down NM_176846 IMAGE:40087301) Doublecortin-like kinase 1, mRNA (cDNA clone -1.064595 -2.26126 2.29 Down NM_019978 IMAGE:5006471) CD302 antigen, mRNA (cDNA clone MGC:7450 -1.11768 -2.3107 2.29 Down NM_025422 IMAGE:3489789) Mono(ADP ribosyl)transferase (Art5 gene), splice -1.630755 -0.43789 2.29 Up NAP069833-1 variant 2 2.22327 3.420905 2.29 Up XR_105471 9130015A21Rik Bone morphogenetic protein 7, mRNA (cDNA clone 4.14843 5.346635 2.29 Up NM_007557 MGC:18610 IMAGE:4218495) RIKEN cDNA C330011K17 gene, mRNA (cDNA 4.012435 2.81863 2.29 Down NM_177712 clone MGC:91167 IMAGE:30458333) Ethanolamine kinase 2, mRNA (cDNA clone 4.98239 3.784995 2.29 Down NM_175443 MGC:178915 IMAGE:9053907) 6.89999 8.094985 2.29 Up NM_021283 Interleukin 4, mRNA (cDNA clone MGC:41086 IMAGE:3376587) Transmembrane protein 135, mRNA (cDNA clone 4.72064 3.526915 2.29 Down NM_028343 MGC:28490 IMAGE:4165990) 5.30459 6.500335 2.29 Up NM_024253 Natural killer cell group 7 sequence (Nkg7), mRNA -1.49071 -2.676645 2.28 Down NM_146753 Olfactory receptor 1195 (Olfr1195), mRNA PREDICTED: Mus musculus hypothetical protein -1.39012 -2.578255 2.28 Down A_55_P2161132 LOC100039946 (LOC100039946), mRNA ENSMUST00000 -1.510135 -2.70225 2.28 Down 023433 Ttk protein kinase (Ttk), transcript variant 1, mRNA Gene model 853, (NCBI), mRNA (cDNA clone -0.907095 -2.094485 2.28 Down NM_001034872 MGC:182564 IMAGE:9056458) N-deacetylase/N-sulfotransferase (heparan -1.67733 -0.486655 2.28 Up NM_031186 glucosaminyl) 3 (Ndst3), mRNA ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3, mRNA (cDNA clone 0.77108 1.961615 2.28 Up NM_139206 IMAGE:4024601) Heme oxygenase (decycling) 1, mRNA (cDNA 1.57495 2.765155 2.28 Up NM_010442 clone MGC:18463 IMAGE:4235374) PREDICTED: Mus musculus similar to Predicted gene, EG545013, transcript variant 1 11.16384 9.972985 2.28 Down A_55_P2060607 (LOC100041119), mRNA Spermatogenesis associated 21, mRNA (cDNA -2.712795 -1.532655 2.27 Up NM_177867 clone MGC:132961 IMAGE:40062125) -2.36451 -1.179465 2.27 Up A_55_P2140760 A_55_P2140760 ENSMUST00000 -2.38065 -1.19922 2.27 Up 103476 Zinc finger protein 780B (Zfp780b), mRNA chrX:20388085- 3.2226 2.04199 2.27 Down 20388552_F chrX:20388085-20388552_F MRNA similar to SPPL2b (cDNA clone 6.91344 5.732635 2.27 Down NM_175195 IMAGE:5695398) KDEL (Lys-Asp-Glu-Leu) containing 1, mRNA -1.812375 -2.987975 2.26 Down NM_023645 (cDNA clone MGC:28356 IMAGE:4018698) Paralemmin 2, mRNA (cDNA clone MGC:130608 -2.10516 -0.92618 2.26 Up NM_172868 IMAGE:40058559) -0.921065 0.25264 2.26 Up NM_011456 NK26 (Serpinb9e) ENSMUST00000 Protein phosphatase 1 (formerly 2C)-like, mRNA -1.13702 -2.315715 2.26 Down 100939 (cDNA clone MGC:106606 IMAGE:6837066) chr18:63455560- -1.280735 -0.10676 2.26 Up 63548085_F chr18:63455560-63548085_F 2.045355 3.22157 2.26 Up AK018540 Transcribed locus Autophagy-related 3 (yeast), mRNA (cDNA clone 5.71819 4.538785 2.26 Down NM_026402 MGC:18909 IMAGE:4241199) 6.08549 4.912055 2.26 Down NM_008228 Histone deacetylase 1 (Hdac1), mRNA 0.728945 1.907245 2.26 Up NM_146600 Olfactory receptor 700 (Olfr700), mRNA chr15:90156889- -1.35451 -2.525695 2.25 Down 90184564_R chr15:90156889-90184564_R -0.48279 -1.65221 2.25 Down NM_176839 ATP-binding cassette protein (Abcc5a) -1.96697 -0.79719 2.25 Up chr1:92412246- chr1:92412246-92423471_R 92423471_R 0.229455 -0.94222 2.25 Down NM_008625 Mannose receptor, C type 1 (Mrc1), mRNA chr5:15146475- 0.84075 2.01299 2.25 Up 15170100_F chr5:15146475-15170100_F Gene trap locus F3b, mRNA (cDNA clone 6.57559 5.407585 2.25 Down NM_025294 MGC:46800 IMAGE:3490657) Tissue inhibitor of metalloproteinase 1, mRNA 8.01624 6.843985 2.25 Down NM_001044384 (cDNA clone MGC:6151 IMAGE:3158222) chr2:168804720- -1.705985 -0.5403 2.24 Up 168854970_R chr2:168804720-168854970_R ENSMUST00000 -1.62093 -0.459485 2.24 Up 070425 Coiled-coil domain containing 65 (Ccdc65), mRNA Spermatogenesis associated glutamate (E)-rich -1.364345 -0.20121 2.24 Up A_55_P2070224 protein 2 (Speer2), mRNA Solute carrier family 5 (sodium/glucose -0.832235 0.32901 2.24 Up NM_146198 cotransporter), member 11 (Slc5a11), mRNA Cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4), mRNA (cDNA clone MGC:5793 -0.817695 0.342665 2.24 Up NM_007670 IMAGE:3495097) -2.058885 -0.897655 2.24 Up NM_007849 Defa25 Endothelin converting enzyme 2 (Ece2), transcript -2.02026 -0.854105 2.24 Up NM_139293 variant 4, mRNA -1.652235 -0.48676 2.24 Up AK006559 Transcribed locus Macrophage stimulating 1 receptor (c-met-related -0.96864 0.19785 2.24 Up NM_009074 tyrosine kinase) (Mst1r), mRNA chr10:114762889 -1.4647 -0.29914 2.24 Up -114763210_F chr10:114762889-114763210_F -0.486555 -1.647485 2.24 Down NM_001163513 Dlg5 chr5:15146475- 0.8494 2.01245 2.24 Up 15170100_F chr5:15146475-15170100_F Chemokine (C-X-C motif) receptor 6 (Cxcr6), 7.28934 8.453185 2.24 Up NM_030712 mRNA 2.221415 3.382975 2.24 Up AK030805 Transcribed locus 3.029735 1.864405 2.24 Down AK012974 Transcribed locus 2.72045 1.554365 2.24 Down NM_028841 Tetraspanin 17 (Tspan17), mRNA Chromatin modifying protein 5, mRNA (cDNA 7.63609 6.474185 2.24 Down NM_029814 clone MGC:6559 IMAGE:2811290) chr14:8576576- -1.197915 -2.354175 2.23 Down 8624104_R chr14:8576576-8624104_R -0.93754 -2.09397 2.23 Down NR_033626 1810010D01Rik ENSMUST00000 PKD1L3 mRNA for polycystic kidney disease 1 like -0.92442 -2.080355 2.23 Down 166288 3 -1.928685 -0.77344 2.23 Up NM_134180 Vomeronasal 1 receptor, C25 (V1rc25), mRNA 2.462405 3.62 2.23 Up NM_013794 Lectin-related NK cell receptor Ly49P chr16:84702353- 4.143915 2.98381 2.23 Down 84710928_F chr16:84702353-84710928_F 5.73124 6.886835 2.23 Up AK040896 Transcribed locus, weakly similar to XP_001152266.1 PREDICTED: similar to gag protein [Pan troglodytes] Transcribed locus, strongly similar to XP_001474702.1 PREDICTED: hypothetical protein -2.490935 -1.33828 2.22 Up AK020160 [Mus musculus] chr6:31017987- -1.839915 -2.99213 2.22 Down 31174287_F chr6:31017987-31174287_F chr3:75451370- -2.392355 -1.239905 2.22 Up 75459674_R chr3:75451370-75459674_R Interleukin 1 receptor, type II, mRNA (cDNA clone 4.97614 6.125935 2.22 Up NM_010555 MGC:41170 IMAGE:1282531) 4.833995 3.685285 2.22 Down XR_108245 LOC100036572 RIKEN cDNA 1810053B01 gene, mRNA (cDNA 3.425625 2.2738 2.22 Down NM_001114079 clone MGC:189833 IMAGE:9007333) Sodium channel modifier 1, mRNA (cDNA clone 6.80609 5.655185 2.22 Down NM_027013 MGC:25899 IMAGE:4220000) -2.129945 -0.98522 2.21 Up NM_001160142 LOC100041256 -2.044785 -0.90155 2.21 Up NM_008192 Guanylate cyclase 2e (Gucy2e), mRNA -0.141965 -1.28507 2.21 Down NM_001160399 Ccdc112 -0.22317 -1.36726 2.21 Down AK005214 Atonal homolog 7 (Drosophila) (Atoh7), mRNA -0.78974 -1.93687 2.21 Down NM_001081391 CUB and Sushi multiple domains 3 (Csmd3), mRNA chr8:72671462- 3.55058 2.40624 2.21 Down 72672533_F chr8:72671462-72672533_F 5.50024 6.644335 2.21 Up NM_138606 Proviral integration site 2 (Pim2), mRNA 3.3867 2.243055 2.21 Down XR_105749 8430426J06Rik Ubiquitin-conjugating enzyme E2W (putative), mRNA (cDNA clone MGC:28304 2.564735 1.421385 2.21 Down NM_025773 IMAGE:4012785) Transcribed locus, strongly similar to XP_921303.1 10.66839 11.813735 2.21 Up A_55_P2011341 PREDICTED: hypothetical protein [Mus musculus] RAB24, member RAS oncogene family, mRNA 8.13619 6.993185 2.21 Down NM_009000 (cDNA clone MGC:25902 IMAGE:4220908) CD8 antigen, alpha chain, mRNA (cDNA clone -0.24005 0.897825 2.2 Up NM_009857 MGC:41580 IMAGE:1247019) Tryptophan hydroxylase 1 (Tph1), transcript variant -0.453915 0.685165 2.2 Up NM_009414 1, mRNA chr11:50994911- -1.876145 -3.015605 2.2 Down 51050704_R chr11:50994911-51050704_R Ferritin mitochondrial (Ftmt), nuclear gene encoding -2.233095 -1.095345 2.2 Up NM_026286 mitochondrial protein, mRNA -2.221775 -1.08631 2.2 Up BY714618 Transcribed locus chr19:53535104- -0.56085 0.579355 2.2 Up 53536627_F chr19:53535104-53536627_F 0.33783 -0.79832 2.2 Down NM_017370 Haptoglobin (Hp), mRNA 0.294195 -0.841405 2.2 Down NM_011755 Zinc finger protein 35 (Zfp35), mRNA 2.58342 3.71835 2.2 Up NM_001038609 Strain ILS microtubule binding protein tau 6.21659 5.07609 2.2 Down NM_028262 SET domain containing 3 (Setd3), mRNA Gene model 1673, (NCBI), mRNA (cDNA clone 4.53179 3.396285 2.2 Down NM_001033458 MGC:182216 IMAGE:9056110) Kruppel-like factor 8, mRNA (cDNA clone 2.46583 1.32917 2.2 Down NM_173780 MGC:99920 IMAGE:30535488) 5.06369 3.923785 2.2 Down NM_026240 GRAM domain containing 3 (Gramd3), mRNA Methylthioribose-1-phosphate isomerase homolog (S. cerevisiae), mRNA (cDNA clone MGC:35655 7.94529 6.806135 2.2 Down NM_026423 IMAGE:4951045) ENSMUST00000 -1.29044 -0.161125 2.19 Up 103685 ENSMUST00000103685 Family with sequence similarity 123, member C -0.541 -1.669475 2.19 Down NM_213727 (Fam123c), mRNA RNA pseudouridylate synthase domain containing 2, mRNA (cDNA clone MGC:143752 -1.285185 -2.41564 2.19 Down NM_173450 IMAGE:40092905) chr14:55672705- -1.22392 -2.356155 2.19 Down 55675212_F chr14:55672705-55675212_F chr16:25517037- -1.453275 -0.323875 2.19 Up 25531362_F chr16:25517037-25531362_F -0.617555 0.510205 2.19 Up NM_001014761 SCN2B mRNA for sodium channel beta2 subunit chr3:78982395- -2.54096 -1.41117 2.19 Up 79094345_R chr3:78982395-79094345_R PREDICTED: Mus musculus hypothetical protein 0.854995 -0.275505 2.19 Down AK033758 LOC100041605 (LOC100041605), mRNA 0.824945 -0.303735 2.19 Down BC122879 Nebulette-like mRNA, partial sequence 3.014815 1.882375 2.19 Down NM_007897 Early B-cell factor 1 (Ebf1), mRNA ENSMUST00000 Enhancer of polycomb homolog 1 (Drosophila) 3.322835 2.19501 2.19 Down 153923 (Epc1), transcript variant 1, mRNA Neural proliferation, differentiation and control gene 1, mRNA (cDNA clone MGC:38033 5.13654 4.003215 2.19 Down NM_008721 IMAGE:5151868) 3.741985 2.611545 2.19 Down NM_025332 GTP-binding protein 8 (putative) (Gtpbp8), mRNA Mitochondrial ribosomal protein L4, mRNA (cDNA 7.07289 5.941035 2.19 Down NM_023167 clone IMAGE:4986909) Arginine vasopressin-induced 1, mRNA (cDNA 9.52739 8.395735 2.19 Down NM_027106 clone MGC:41363 IMAGE:1344413) ENSMUST00000 8.30429 7.172635 2.19 Down 010286 Tnfrsf13b DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast) -2.2182 -1.091775 2.18 Up NM_010059 (Dmc1), mRNA chr16:50715231- -2.1474 -1.02439 2.18 Up 50841124_F chr16:50715231-50841124_F RIKEN cDNA A630033E08 gene -1.57657 -2.697735 2.18 Down NM_177358 (A630033E08Rik), transcript variant 1, mRNA RIKEN cDNA 2810426N06 gene, mRNA (cDNA -0.6875 -1.81257 2.18 Down NM_023363 clone MGC:38213 IMAGE:5323247) Calcium channel, voltage-dependent, gamma subunit -1.326085 -2.452935 2.18 Down NM_133190 8 (Cacng8), mRNA chr14:77077374- -1.286355 -2.41233 2.18 Down 77086910_F chr14:77077374-77086910_F chr12:3199327- -0.858075 -1.985295 2.18 Down 3200827_F chr12:3199327-3200827_F -2.457805 -1.33419 2.18 Up NM_001011828 Olfactory receptor 304 (Olfr304), mRNA Von Willebrand factor A domain containing 5A, 0.306835 -0.82066 2.18 Down NM_172767 mRNA (cDNA clone MGC:6690 IMAGE:3582797) 0.184005 -0.94304 2.18 Down NM_015798 F-box protein FBX15 0.72426 1.8465 2.18 Up NM_178412 CDNA sequence BC051070 (BC051070), mRNA chr1:167797581- 2.8218 1.695435 2.18 Down 167803031_R chr1:167797581-167803031_R Adenosine A3 receptor, mRNA (cDNA clone 3.015665 4.138295 2.18 Up NM_009631 IMAGE:1448868) Solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20, 2.531035 1.406285 2.18 Down NM_020520 mRNA (cDNA clone MGC:25786 IMAGE:401 chr5:92548501- 1.746505 0.6218 2.18 Down 92566401_F chr5:92548501-92566401_F Glycophorin C, mRNA (cDNA clone MGC:37138 6.27314 5.148685 2.18 Down NM_001048207 IMAGE:4952917) PREDICTED: Mus musculus predicted gene, -0.3093 -1.4286 2.17 Down BC038648 EG629300 (EG629300), mRNA -0.85081 -1.970305 2.17 Down NM_001190373 Kcng2 Transcription elongation factor A (SII)-like 8, mRNA (cDNA clone MGC:27945 -0.845675 -1.963125 2.17 Down NM_025703 IMAGE:3588435) Sarcolipin, mRNA (cDNA clone MGC:41044 -0.803425 0.311205 2.17 Up NM_025540 IMAGE:1397989) -2.295755 -1.181075 2.17 Up NM_021464 Brain RPTPmam4 isoform III ENSMUST00000 Protein phosphatase 3, catalytic subunit, beta -1.99354 -0.877555 2.17 Up 103337 isoform, mRNA (cDNA clone IMAGE:5375983) 4.11095 2.99541 2.17 Down NM_030082 Histone cluster 3, H2ba (Hist3h2ba), mRNA 2.977475 1.86199 2.17 Down NM_025718 Deoxyribonuclease 1-like 2 (Dnase1l2), mRNA Coiled-coil domain containing 123, mRNA (cDNA 2.05221 0.9324 2.17 Down NM_028120 clone MGC:7462 IMAGE:3490246) chr6:86776350- 2.05607 0.93855 2.17 Down 86799379_R chr6:86776350-86799379_R chr16:84708695- 7.16714 6.051635 2.17 Down 84708806_F chr16:84708695-84708806_F Guanine nucleotide binding protein (G protein), gamma 3, mRNA (cDNA clone MGC:36069 2.031425 0.91354 2.17 Down NM_010316 IMAGE:5365311) Bromodomain adjacent to zinc finger domain, 2B, mRNA (cDNA clone MGC:183725 4.75844 3.64134 2.17 Down NM_001001182 IMAGE:9087725) RIKEN cDNA 1810033B17 gene (1810033B17Rik), 3.84382 2.727345 2.17 Down NM_026985 mRNA -1.44061 -2.54871 2.16 Down A_55_P2060849 Deubiquitinating enzyme UBH1 RIKEN cDNA 2010015L04 gene, mRNA (cDNA -2.318225 -1.208775 2.16 Up NM_177674 clone IMAGE:40094233) -1.59565 -0.48393 2.16 Up NM_001177886 Igsf5 -0.690635 -1.80049 2.16 Down NM_007559 Bone morphogenetic protein 8b (Bmp8b), mRNA Ectonucleoside triphosphate diphosphohydrolase 3 0.73052 1.841365 2.16 Up NM_178676 (Entpd3) Palladin, cytoskeletal associated protein, mRNA 2.31584 1.20213 2.16 Down NM_001081390 (cDNA clone IMAGE:4947562) 3.670415 2.557155 2.16 Down NM_198108 MORN repeat containing 4 (Morn4), mRNA Nuclear receptor subfamily 1, group D, member 2 3.50378 2.391955 2.16 Down BC096461 (Nr1d2), mRNA Protein disulfide isomerase associated 2 (Pdia2), 2.98447 1.873275 2.16 Down NM_001081070 mRNA Tetraspanin 6, mRNA (cDNA clone MGC:5801 5.65769 4.54761 2.16 Down NM_019656 IMAGE:3590862) 5.17339 6.286235 2.16 Up NM_145158 Strain C57BL/6J basilin chr1:138592780- -1.56872 -2.67343 2.15 Down 138622719_F chr1:138592780-138622719_F chr14:22267795- -1.679605 -0.572265 2.15 Up 22319045_R chr14:22267795-22319045_R PREDICTED: Mus musculus hypothetical protein -1.45835 -2.564715 2.15 Down AK139702 LOC100043169 (LOC100043169), mRNA -1.134935 -2.2381 2.15 Down TC1584441 TC1584441 -1.88347 -0.78138 2.15 Up AK016536 Transcribed locus -1.87247 -0.76687 2.15 Up NM_147035 Olfactory receptor 711 (Olfr711), mRNA chr9:96664617- -0.95818 0.144125 2.15 Up 96683617_F chr9:96664617-96683617_F chr12:52950465- -0.903145 -2.004655 2.15 Down 52950990_R chr12:52950465-52950990_R chr10:78969674- -1.757575 -0.650915 2.15 Up 78981039_F chr10:78969674-78981039_F Heterogeneous nuclear ribonucleoprotein A3, mRNA (cDNA clone MGC:36649 4.60334 5.705285 2.15 Up NM_198090 IMAGE:5362605) Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta, mRNA (cDNA 2.10528 1.002215 2.15 Down NM_010908 clone MGC:36057 IMAGE:5136809) chr2:143991240- -2.323475 -1.224195 2.14 Up 143991597_F chr2:143991240-143991597_F Anaphase promoting complex subunit 10, mRNA -1.570005 -2.668 2.14 Down NM_026904 (cDNA clone MGC:25547 IMAGE:3710036) Chitinase 1 (chitotriosidase), mRNA (cDNA clone -1.52083 -0.42237 2.14 Up NM_027979 MGC:170392 IMAGE:8861787) -0.534665 -1.631815 2.14 Down NM_001163614 Ascl4 -0.916995 0.1797 2.14 Up NM_027754 Rnf148 chr5:45400409- -1.3053 -0.20565 2.14 Up 45815639_R chr5:45400409-45815639_R -0.808165 0.28996 2.14 Up NM_010730 Annexin A1, mRNA (cDNA clone MGC:8074 IMAGE:3587973) chr1:6199946- -0.23981 -1.33672 2.14 Down 6200603_R chr1:6199946-6200603_R Collagen, type XVIII, alpha 1 (Col18a1), transcript 2.50976 3.6105 2.14 Up NM_001109991 variant 2, mRNA Mucin 13, epithelial transmembrane, mRNA (cDNA 3.37268 4.473 2.14 Up NM_010739 clone MGC:18590 IMAGE:4219376) Protein disulfide isomerase associated 2 (Pdia2), 2.94061 1.841905 2.14 Down NM_001081070 mRNA Olfactory receptor 873, mRNA (cDNA clone 11.59344 10.495085 2.14 Down A_55_P1993348 MGC:170767 IMAGE:8862162) 10.38069 9.285085 2.14 Down NM_133362 Erythroid differentiation regulator 1 (Erdr1), mRNA RIKEN cDNA 2210010C17 gene, mRNA (cDNA 4.06615 5.160885 2.14 Up NM_027308 clone MGC:171085 IMAGE:8862480) RAR-related orphan receptor gamma, mRNA 3.79776 2.69806 2.14 Down NM_011281 (cDNA clone MGC:25220 IMAGE:4489193) Six transmembrane epithelial antigen of prostate 2 -1.181995 -2.27416 2.13 Down NM_001103157 (Steap2), transcript variant 2, mRNA -0.75622 -1.84967 2.13 Down NM_144807 Choline phosphotransferase 1 (Chpt1), mRNA chr2:143988645- -2.271995 -1.18126 2.13 Up 143993945_R chr2:143988645-143993945_R chr8:72178035- -1.19049 -2.284255 2.13 Down 72200445_F chr8:72178035-72200445_F -2.103425 -1.011685 2.13 Up AK020838 Transcribed locus -2.044775 -0.95422 2.13 Up NR_015351 Ipw -2.185085 -1.095235 2.13 Up NM_146887 Olfactory receptor 1301 (Olfr1301), mRNA 0.068545 -1.02351 2.13 Down NM_144935 CDNA sequence BC018242 (BC018242), mRNA 0.90652 1.99437 2.13 Up NM_181072 Myosin IE (Myo1e), mRNA chr2:52241435- 1.298245 2.39052 2.13 Up 52245307_F chr2:52241435-52245307_F WD repeat and FYVE domain containing 4 (Wdfy4), 2.272285 1.18026 2.13 Down NM_001146022 mRNA chr5:35975265- 6.46899 5.376485 2.13 Down 35982561_R chr5:35975265-35982561_R Cysteine and histidine rich 1, mRNA (cDNA clone 5.23909 4.145625 2.13 Down NM_180962 IMAGE:5373573) RIKEN cDNA 2010002N04 gene (2010002N04Rik), 7.66574 6.572635 2.13 Down NM_134133 mRNA 7.67764 6.583635 2.13 Down NM_001204875 Set ENSMUST00000 9.13359 10.222485 2.13 Up 082411 ND3 ENSMUST00000 -1.493585 -2.5758 2.12 Down 037976 Tomoregulin-1 (M7365) (TR-1 gene) chr4:114627748- -1.494075 -2.576145 2.12 Down 114632898_F chr4:114627748-114632898_F -1.523205 -0.43906 2.12 Up NM_201370 Strain C57BL/6J Wee1B protein kinase 1.64104 2.72381 2.12 Up NM_001198933 Me1 2.248615 3.333255 2.12 Up NM_001038609 Strain ILS microtubule binding protein tau Integrin alpha E, epithelial-associated (Itgae), 3.29329 4.380225 2.12 Up NM_172944 transcript variant 1, mRNA 1.857295 0.776125 2.12 Down NM_145629 Plastin 3 (T-isoform) (Pls3), mRNA 7.70624 8.793535 2.12 Up NM_008091 GATA binding protein 3 (Gata3), mRNA 2.585895 1.499905 2.12 Down XR_105398 LOC100502705 ENSMUST00000 2.96571 1.880795 2.12 Down 087884 Gene model 973, (NCBI) (Gm973), mRNA 5.83239 4.7462 2.12 Down NM_130879 Ubiquitin specific peptidase 48 (Usp48), mRNA 12.09459 11.010235 2.12 Down NM_026533 Ribosomal protein S13 (Rps13), mRNA chr8:85609155- -1.56698 -2.64558 2.11 Down 85615170_F chr8:85609155-85615170_F Chemokine (C-C motif) ligand 20, mRNA (cDNA -1.667755 -2.743695 2.11 Down NAP068993-1 clone MGC:41109 IMAGE:1380543) chr7:131819366- -2.11591 -1.03808 2.11 Up 131852866_F chr7:131819366-131852866_F chr8:90048940- -1.706775 -2.78667 2.11 Down 90049461_F chr8:90048940-90049461_F -2.22014 -1.145185 2.11 Up BE650233 Transcribed locus chr16:59557120- -1.097955 -2.1749 2.11 Down 59602070_R chr16:59557120-59602070_R Strain DBA/2J MS4a5 protein mRNA, complete cds; -1.158265 -2.235895 2.11 Down NM_183190 alternatively spliced chr2:67411703- -1.361415 -2.437725 2.11 Down 67412293_F chr2:67411703-67412293_F chr18:35976163- -1.20044 -0.12552 2.11 Up 35976530_F chr18:35976163-35976530_F chr14:62263564- -1.474645 -0.397185 2.11 Up 62308286_F chr14:62263564-62308286_F -1.034485 0.045225 2.11 Up NM_146653 Olfactory receptor 435 (Olfr435), mRNA chr17:79042382- -1.045875 -2.12233 2.11 Down 79051807_R chr17:79042382-79051807_R 7.44464 6.368985 2.11 Down NM_007713 Cdc2/CDC28-like protein CLK3, partial 10.16909 9.090085 2.11 Down TC1700876 TC1700876 Serine (or cysteine) peptidase inhibitor, clade B, member 5, mRNA (cDNA clone MGC:5950 4.91129 3.83591 2.11 Down NM_009257 IMAGE:3600282) -1.880915 -2.95081 2.1 Down NM_013679 Seminal vesicle secretory protein 6 (Svs6), mRNA Ependymin related protein 1 (zebrafish) (Epdr1), -2.26015 -1.189025 2.1 Up NM_134065 mRNA WD and tetratricopeptide repeats 1, mRNA (cDNA -1.3539 -2.423285 2.1 Down NM_199306 clone MGC:37830 IMAGE:5099225) Naked cuticle 2 homolog (Drosophila), mRNA -0.919435 -1.99291 2.1 Down NM_028186 (cDNA clone MGC:28383 IMAGE:4021772) -0.99239 -2.064985 2.1 Down NM_139222 Defensin beta 15 (Defb15), mRNA ENSMUST00000 Solute carrier family 35, member C2 (Slc35c2), -2.185355 -1.113935 2.1 Up 114743 mRNA chr14:26093652- -1.575505 -0.50792 2.1 Up 26208156_R chr14:26093652-26208156_R chr1:171402829- -1.439435 -0.369945 2.1 Up 171403289_R chr1:171402829-171403289_R 1.919575 2.99144 2.1 Up NM_011338 Strain SJL/J small inducible cytokine A10 (ScyA10) chr6:86776350- 1.384175 0.317105 2.1 Down 86799379_R chr6:86776350-86799379_R 6.49634 7.565285 2.1 Up NM_016780 Integrin beta 3 (Itgb3), mRNA 4.386045 5.453885 2.1 Up NM_011073 Perforin 1 (pore forming protein) (Prf1), mRNA POU domain, class 6, transcription factor 1 4.18751 3.11978 2.1 Down NM_010127 (Pou6f1), mRNA 8.02859 6.960985 2.1 Down A_55_P2040519 A_55_P2040519 -1.53456 -0.470065 2.09 Up AK132706 Transcribed locus chr9:7214754- -1.542935 -2.606165 2.09 Down 7225700_R chr9:7214754-7225700_R STEAP family member 3, mRNA (cDNA clone -0.4891 0.57607 2.09 Up NM_001085409 MGC:47007 IMAGE:2651584) chr18:55040319- -1.745705 -0.681535 2.09 Up 55040708_R chr18:55040319-55040708_R chr4:89032648- -1.45201 -0.390225 2.09 Up 89133273_F chr4:89032648-89133273_F chr13:54399275- -0.41688 -1.483305 2.09 Down 54445825_R chr13:54399275-54445825_R Interleukin 1 receptor-like 1 (Il1rl1), transcript 1.52803 2.594595 2.09 Up NM_001025602 variant 2, mRNA 2.099595 3.162405 2.09 Up NM_029210 Sv2c 1.624845 2.68893 2.09 Up NM_022378 Forkhead box B1 (Foxb1), mRNA chr6:83541250- 3.44716 2.383465 2.09 Down 83560425_F chr6:83541250-83560425_F Arginine decarboxylase, mRNA (cDNA clone 3.0615 4.122045 2.09 Up NM_172875 MGC:170601 IMAGE:8861996) 2.666985 3.728435 2.09 Up NM_001190448 Ddc Transmembrane protein 37, mRNA (cDNA clone 2.99384 4.059935 2.09 Up NM_019432 MGC:25884 IMAGE:4215775) 1.90022 0.834805 2.09 Down AK079356 Transcribed locus Zinc finger, FYVE domain containing 28, mRNA 1.20169 0.139905 2.09 Down NM_001015039 (cDNA clone MGC:170678 IMAGE:8862073) 10.80944 11.873035 2.09 Up NM_010370 Granzyme A (Gzma), mRNA CMAH mRNA for CMP-NeuAc hydroxylase, 3.435365 2.37479 2.09 Down NM_001111110 complete cds, major form of alternative splicing chr12:12876192- -1.9154 -0.861865 2.08 Up 12918398_F chr12:12876192-12918398_F ENSMUST00000 -1.262135 -0.205475 2.08 Up 051774 Eph receptor A5 (Epha5), mRNA ENSMUST00000 Vestigial like 2 homolog (Drosophila) (Vgll2), -1.54638 -2.60448 2.08 Down 100180 mRNA RIKEN cDNA 1200009O22 gene (1200009O22Rik), -2.18793 -1.13251 2.08 Up NM_025817 mRNA -0.94774 -2.00417 2.08 Down AK016907 Transcribed locus chrX:148819227- -1.75526 -0.69616 2.08 Up 148844227_R chrX:148819227-148844227_R Cell death-inducing DNA fragmentation factor, -1.17226 -2.225725 2.08 Down NM_007702 alpha subunit-like effector A (Cidea), mRNA -2.39507 -1.340315 2.08 Up NM_001007268 Dual-specificity phosphatase TS-DSP6 chr14:79724027- -1.939995 -0.88608 2.08 Up 79729152_R chr14:79724027-79729152_R ENSMUST00000 -1.729105 -0.669615 2.08 Up 062544 ENSMUST00000062544 Potassium channel, subfamily T, member 1 (Kcnt1), -1.085 -2.14178 2.08 Down NM_175462 transcript variant 2, mRNA AlkB, alkylation repair homolog 5 (E. coli), mRNA 5.87439 4.816955 2.08 Down NM_172943 (cDNA clone MGC:62491 IMAGE:6401541) Tumor necrosis factor (ligand) superfamily, member 2.928085 3.98174 2.08 Up NM_009425 10 (Tnfsf10), mRNA Nuclear receptor subfamily 4, group A, member 2 3.819055 2.759065 2.08 Down NM_013613 (Nr4a2), transcript variant 1, mRNA Protein associated with topoisomerase II homolog 1 (yeast), mRNA (cDNA clone MGC:66563 4.66964 3.611335 2.08 Down NM_172635 IMAGE:6825758) G protein-coupled receptor 77 (Gpr77), transcript 3.33158 2.27625 2.08 Down NM_176912 variant 2, mRNA Hepatoma-derived growth factor, mRNA (cDNA 4.65024 3.59685 2.08 Down NM_008231 clone MGC:14030 IMAGE:4163897) chr12:86420883- -1.54556 -2.59779 2.07 Down 86421380_F chr12:86420883-86421380_F -1.819835 -0.767645 2.07 Up NM_001163539 5430427O19Rik ENSMUST00000 Paternally expressed 10 (Peg10), transcript variant 1, -2.27104 -1.22475 2.07 Up 152599 mRNA -2.403215 -1.353355 2.07 Up NM_013794 Lectin-related NK cell receptor Ly49P chr1:77819988- -0.90505 -1.952485 2.07 Down 77820546_F chr1:77819988-77820546_F -1.556005 -0.507595 2.07 Up NR_015521 1700030C10Rik Developmental pluripotency associated 1, mRNA -1.857485 -0.8111 2.07 Up NM_178247 (cDNA clone MGC:144866 IMAGE:40106955) -1.82063 -0.772015 2.07 Up NM_176971 Rab9B 1.212815 2.26195 2.07 Up NM_001198933 Me1 chr5:35975265- 2.44053 1.3884 2.07 Down 35982561_R chr5:35975265-35982561_R Synaptic nuclear envelope 1 (Syne1), transcript 2.703995 1.65528 2.07 Down NM_153399 variant 1, mRNA Growth associated protein 43, mRNA (cDNA clone 3.7567 2.70725 2.07 Down NM_008083 MGC:25402 IMAGE:4503501) chr12:12876192- -1.80558 -0.76317 2.06 Up 12918398_R chr12:12876192-12918398_R Mitochondrial carrier triple repeat 6 (Mcart6), -1.572185 -2.61417 2.06 Down NM_001082412 nuclear gene encoding mitochondrial protein, transcript variant 2, mRNA chr1:90508551- -1.53303 -0.490255 2.06 Up 90508788_R chr1:90508551-90508788_R -1.313745 -2.35326 2.06 Down NM_010259 Guanylate binding protein 1 (Gbp1), mRNA Six transmembrane epithelial antigen of prostate 2 -1.790075 -0.749045 2.06 Up NM_001103157 (Steap2), transcript variant 2, mRNA Ciliary rootlet coiled-coil, rootletin, mRNA (cDNA -1.8024 -0.756555 2.06 Up A_55_P2066017 clone IMAGE:4481964) chr6:54592523- -0.79369 -1.839175 2.06 Down 54593344_R chr6:54592523-54593344_R 1.91968 2.96208 2.06 Up NM_138653 B-box and SPRY domain containing (Bspry), mRNA chr16:84707202- 4.04181 2.99637 2.06 Down 84707748_F chr16:84707202-84707748_F 3.29885 2.25733 2.06 Down NM_001177858 Trim43c Myosin VIIB, mRNA (cDNA clone -1.52742 -2.560705 2.05 Down NM_032394 IMAGE:4218783) chr14:62263564- -1.19335 -2.22811 2.05 Down 62307496_F chr14:62263564-62307496_F -2.068095 -1.029045 2.05 Up TC1612888 TC1612888 Solute carrier family 10 (sodium/bile acid -2.15355 -1.12081 2.05 Up NM_029415 cotransporter family), member 6 (Slc10a6), mRNA chr4:55465247- -1.750075 -0.7162 2.05 Up 55494547_R chr4:55465247-55494547_R Activating transcription factor 1, mRNA (cDNA -0.23348 -1.265825 2.05 Down AK148500 clone MGC:6482 IMAGE:2646620) Annexin A1, mRNA (cDNA clone MGC:8074 1.41965 2.456985 2.05 Up NM_010730 IMAGE:3587973) Collagen, type XVIII, alpha 1 (Col18a1), transcript 3.144415 4.18338 2.05 Up NM_001109991 variant 2, mRNA 5.28789 4.252105 2.05 Down A_55_P2148385 A_55_P2148385 5.84804 4.80962 2.05 Down NM_011232 RAD1 homolog (S. pombe) (Rad1), mRNA RIKEN cDNA 2900078C09 gene, mRNA (cDNA -1.757455 -2.782995 2.04 Down NAP112752-1 clone IMAGE:5358868) chrX:18734106- -2.01366 -0.982205 2.04 Up 18744367_R chrX:18734106-18744367_R ENSMUST00000 Caudal type homeo box 1, mRNA (cDNA clone -1.760535 -2.78693 2.04 Down 098120 MGC:28644 IMAGE:4224352) -1.56988 -2.600495 2.04 Down NAP113348-1 NAP113348-1 chr1:175705225- -1.58016 -0.55156 2.04 Up 175717250_F chr1:175705225-175717250_F ENSMUST00000 Polymerase (DNA directed), gamma 2, accessory -0.772755 -1.80067 2.04 Down 102924 subunit (Polg2), mRNA chr4:109071198- -1.84292 -0.812915 2.04 Up 109078776_F chr4:109071198-109078776_F chr6:5311375- -1.41135 -2.441015 2.04 Down 5328075_F chr6:5311375-5328075_F chr9:96673952- -0.63261 -1.660335 2.04 Down 96674816_F chr9:96673952-96674816_F Formiminotransferase cyclodeaminase, mRNA -0.47073 0.55961 2.04 Up NM_080845 (cDNA clone MGC:37815 IMAGE:5098529) -0.10871 -1.13824 2.04 Down XR_106569 Gm4129 56 kdal protein mRNA from an interferon activated 0.199495 -0.82999 2.04 Down NM_001033450 gene, exon 2, 5 end, mRNA sequence Transcribed locus, moderately similar to XP_001072875.1 PREDICTED: hypothetical protein 2.09747 1.067245 2.04 Down AK034163 [Rattus norvegicus] Jumonji domain containing 2D, mRNA (cDNA 1.26281 2.29405 2.04 Up NM_173433 clone IMAGE:40056755) 2.128195 1.09995 2.04 Down NM_019753 Cadherin 17 (Cdh17), mRNA 3.783875 2.757385 2.04 Down NM_021568 Poly(rC) binding protein 3 (Pcbp3), mRNA 10.95429 9.926235 2.04 Down A_55_P1973279 A_55_P1973279 Predicted gene, ENSMUSG00000051554, mRNA 3.490815 2.464845 2.04 Down BC022771 (cDNA clone MGC:32180 IMAGE:5005221) chr2:52241435- -1.220435 -0.20025 2.03 Up 52245307_F chr2:52241435-52245307_F chr17:22815742- -1.497695 -2.51786 2.03 Down 22828592_R chr17:22815742-22828592_R Protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b, mRNA (cDNA clone -1.444935 -2.46943 2.03 Down NM_023587 MGC:6798 IMAGE:2647850) Transmembrane protein 90a, mRNA (cDNA clone -2.196855 -1.176725 2.03 Up NAP001637-001 MGC:170126 IMAGE:8861521) -2.27328 -1.24955 2.03 Up NM_010782 Strain C57BL/6 mast cell protease-9 chr8:48476637- -1.98804 -0.967165 2.03 Up 48492537_R chr8:48476637-48492537_R RIKEN cDNA 1700010M22 gene -1.500145 -0.481385 2.03 Up NM_025490 (1700010M22Rik), mRNA ENSMUST00000 -0.981435 -2.005765 2.03 Down 070911 Apol8 Meteorin, glial cell differentiation regulator-like -1.869705 -0.849295 2.03 Up NM_144797 (Metrnl), mRNA -1.295685 -0.27645 2.03 Up A_55_P2180156 Vomeronasal 1 receptor, H13 (V1rh13), mRNA -2.226445 -1.20406 2.03 Up NM_146985 Olfactory receptor 1270 (Olfr1270), mRNA chr3:70581406- -0.877755 0.14648 2.03 Up 70614856_R chr3:70581406-70614856_R Glucosaminyl (N-acetyl) transferase 1, core 2, mRNA (cDNA clone MGC:11452 2.24945 3.270625 2.03 Up NM_173442 IMAGE:3154671) 1.299055 2.317325 2.03 Up NM_010651 MHC class I recognition receptor Ly49I chr5:110424250- 3.549075 2.53062 2.03 Down 110443025_F chr5:110424250-110443025_F Suppression of tumorigenicity 5, mRNA (cDNA 1.89413 0.870195 2.03 Down NM_001001326 clone IMAGE:4984792) PREDICTED: Mus musculus similar to galactose 3- O-sulfotransferase-2, transcript variant 2 1.44518 0.422215 2.03 Down NM_199366 (LOC100041596), mRNA chr13:94182877- 4.99384 3.96957 2.03 Down 94203935_R chr13:94182877-94203935_R Tetratricopeptide repeat domain 30A1 (Ttc30a1), 2.085125 1.06483 2.03 Down NM_030188 mRNA Receptor (calcitonin) activity modifying protein 1, 6.15529 5.135785 2.03 Down NM_016894 mRNA (cDNA clone IMAGE:5323866) Eukaryotic translation elongation factor 1 gamma, mRNA (cDNA clone MGC:30982 8.81509 7.793835 2.03 Down NM_026007 IMAGE:5251765) chr14:52864224- -1.033995 -2.045645 2.02 Down 52878449_F chr14:52864224-52878449_F -1.47592 -2.4887 2.02 Down AK044991 Zbtb49 -1.640295 -2.656815 2.02 Down NM_001198587 Nrxn3 Cyclin-dependent kinase inhibitor 2A (Cdkn2a), -0.449415 0.56248 2.02 Up NM_009877 transcript variant 1, mRNA Transcribed locus, weakly similar to XP_001055262.1 PREDICTED: similar to cerebellar -1.528615 -0.51144 2.02 Up CB248850 degeneration-related protein 1, 34kDa [R Phospholipase A2, group IVA (cytosolic, calcium- dependent), mRNA (cDNA clone MGC:6168 -1.072355 -2.08653 2.02 Down NM_008869 IMAGE:3485483) -0.808095 -1.822345 2.02 Down NR_038043 Gm10033 Peptidase M20 domain containing 1, mRNA (cDNA -0.92174 -1.93292 2.02 Down NM_178079 clone IMAGE:5124369) 1.4546 2.47215 2.02 Up NM_001033465 CDNA clone IMAGE:9054022 3.088025 4.102535 2.02 Up NM_007413 Adenosine A2b receptor (Adora2b), mRNA Cytochrome P450, family 11, subfamily a, polypeptide 1 (Cyp11a1), nuclear gene encoding 5.60109 6.617635 2.02 Up NM_019779 mitochondrial protein, mRNA 3.10447 4.120605 2.02 Up NM_146191 Leucine-rich repeat kinase 1 (Lrrk1), mRNA Membrane-spanning 4-domains, subfamily A, member 6B, mRNA (cDNA clone MGC:35625 3.753925 2.736455 2.02 Down NM_027209 IMAGE:3984299) Neural cell adhesion molecule 1 (Ncam1), transcript -0.77203 -1.781985 2.01 Down NM_010875 variant 2, mRNA chr6:90749574- -1.34089 -2.344975 2.01 Down 90750492_R chr6:90749574-90750492_R -1.173615 -2.18272 2.01 Down NM_001081124 MAP7 domain containing 2 (Mtap7d2), mRNA Jumonji, AT rich interactive domain 1C (Rbp2 like) -1.796795 -0.791745 2.01 Up A_55_P1997184 (Jarid1c), mRNA chr13:95613081- -2.22468 -1.214265 2.01 Up 95640256_F chr13:95613081-95640256_F RIKEN cDNA 2310034C09 gene (2310034C09Rik), -2.495165 -1.488635 2.01 Up NM_054100 mRNA Diacylglycerol O-acyltransferase 2-like 4, mRNA 0.740615 -0.269655 2.01 Down A_55_P2062535 (cDNA clone MGC:169709 IMAGE:8861104) 3.616945 2.60937 2.01 Down NM_153389 ATPase, class V, type 10D (Atp10d), mRNA 3.788475 2.781705 2.01 Down NM_134251 Solute carrier family 12 (potassium/chloride transporters), member 8, mRNA (cDNA clone MGC:31673 IMAGE:4910321) chr12:85210777- 2.92576 1.917845 2.01 Down 85262127_R chr12:85210777-85262127_R 3.34562 2.339145 2.01 Down NM_144881 Hedgehog acyltransferase (Hhat), mRNA Protein kinase, cAMP dependent, catalytic, beta 5.17984 4.172275 2.01 Down NM_011100 (Prkacb), mRNA Signal recognition particle 9, mRNA (cDNA clone 7.63724 6.631235 2.01 Down NM_012058 MGC:49477 IMAGE:5353755) Solute carrier family 25, member 34 (Slc25a34), 3.708 2.701445 2.01 Down NAP093863-001 mRNA -1.606485 -2.609335 2 Down NM_030554 RAB27B (Yrcmrab27b) Receptor transporter protein 4, mRNA (cDNA clone -0.81119 0.18716 2 Up NM_023386 MGC:28210 IMAGE:3990099) -0.739455 -1.74141 2 Down AK045926 Transcribed locus chr6:52046805- -1.57323 -0.575275 2 Up 52072744_R chr6:52046805-52072744_R chr6:125330524- -0.896515 -1.894285 2 Down 125410249_F chr6:125330524-125410249_F chr4:124127144- -0.166685 -1.169235 2 Down 124334840_R chr4:124127144-124334840_R RIKEN cDNA 1810019J16 gene (1810019J16Rik), -1.600065 -0.60272 2 Up NM_001083916 transcript variant 2, mRNA chr18:54115625- -0.41364 -1.41703 2 Down 54123729_F chr18:54115625-54123729_F Predicted gene, OTTMUSG00000010136 -1.919745 -0.920645 2 Up NM_001039595 (OTTMUSG00000010136), mRNA -2.242275 -1.24152 2 Up A_55_P2159315 A_55_P2159315 RIKEN cDNA 1700006A11 gene (1700006A11Rik), -0.793155 -1.79156 2 Down NM_027939 mRNA Hypothetical protein LOC100042450 -1.76936 -0.77277 2 Up NM_001134752 (LOC100042450), mRNA chr18:78190463- -1.29889 -0.298405 2 Up 78235438_R chr18:78190463-78235438_R 0.554035 -0.44265 2 Down NM_010296 GLI-Kruppel family member GLI1 (Gli1), mRNA 3.733065 4.73625 2 Up NM_001161355 Timd2 1.205825 2.20707 2 Up NM_146191 Leucine-rich repeat kinase 1 (Lrrk1), mRNA 7.78499 6.786135 2 Down XR_105894 1700097N02Rik 1.86842 0.87054 2 Down NM_145629 Plastin 3 (T-isoform) (Pls3), mRNA CD79B antigen, mRNA (cDNA clone MGC:18588 4.12793 5.125985 2 Up NM_008339 IMAGE:4164551) 3.990345 2.98832 2 Down NM_001174047 Cacna2d2 chr2:22782700- 2.875445 1.875305 2 Down 22801900_R chr2:22782700-22801900_R chr2:119697845- 4.24894 3.251495 2 Down 119719245_F chr2:119697845-119719245_F chrX:121675099- -2.004455 -1.013885 1.99 Up 121675731_F chrX:121675099-121675731_F -2.56793 -1.575495 1.99 Up AK020664 Transcribed locus chr10:83181374- -1.47948 -2.474835 1.99 Down 83249918_F chr10:83181374-83249918_F ENSMUST00000 RIKEN cDNA 1110006G06 gene, mRNA (cDNA -0.907245 0.086995 1.99 Up 110854 clone MGC:32341 IMAGE:5029298) -0.70195 -1.69441 1.99 Down NM_001163610 Nhsl2 ENSMUST00000 -2.318095 -1.322795 1.99 Up 137459 Transcribed locus chr5:74487385- -1.543575 -2.536995 1.99 Down 74497428_R chr5:74487385-74497428_R chr9:32416123- -1.86027 -0.8661 1.99 Up 32416560_R chr9:32416123-32416560_R chr9:46894029- -1.96483 -0.9713 1.99 Up 46973977_R chr9:46894029-46973977_R chr1:134245856- -0.452465 -1.4471 1.99 Down 134246607_F chr1:134245856-134246607_F Olfactory receptor 282, mRNA (cDNA clone -1.1407 -0.149775 1.99 Up NM_146457 IMAGE:40136631) -1.25325 -0.259635 1.99 Up NR_033138 Gm833 -1.294915 -0.304285 1.99 Up NM_197996 Tetraspanin 15 (Tspan15), mRNA Nuclear factor, erythroid derived 2,-like 1, mRNA -1.60252 -0.60715 1.99 Up A_55_P2022287 (cDNA clone IMAGE:5116375) chr7:89433125- -0.47566 0.520025 1.99 Up 89464275_R chr7:89433125-89464275_R ATPase, aminophospholipid transporter-like, class I, -0.35718 -1.35135 1.99 Down NM_015803 type 8A, member 2 (Atp8a2), mRNA Fibroblast growth factor receptor 1, mRNA (cDNA 1.22477 2.219965 1.99 Up NM_010206 clone MGC:25398 IMAGE:4037899) 2-cell-stage, variable group, member 3 (Tcstv3), 0.565165 -0.42804 1.99 Down NM_153523 mRNA Endothelial cell-specific molecule 1, mRNA (cDNA 5.92409 6.914385 1.99 Up NM_023612 clone MGC:28355 IMAGE:4018658) chr5:23349978- 3.894805 2.898815 1.99 Down 23402028_F chr5:23349978-23402028_F chr5:35975265- 7.82074 6.825835 1.99 Down 35982561_R chr5:35975265-35982561_R 2.311545 1.319435 1.99 Down NM_010687 Like-glycosyltransferase (Large), mRNA Transducin-like enhancer of split 1, homolog of 5.53664 4.541125 1.99 Down NM_011599 Drosophila E(spl) (Tle1), mRNA Zinc finger protein 260, mRNA (cDNA clone 7.56599 6.576735 1.99 Down NM_011981 IMAGE:5025492) Acylphosphatase 1, erythrocyte (common) type -0.535485 -1.520325 1.98 Down NM_025421 (Acyp1), mRNA chr4:123572090- -0.995665 -1.984125 1.98 Down 123581365_F chr4:123572090-123581365_F chr7:57115122- -1.67042 -2.652365 1.98 Down 57121735_R chr7:57115122-57121735_R chr3:58730418- -1.842225 -2.82474 1.98 Down 58742493_F chr3:58730418-58742493_F -2.27274 -1.28846 1.98 Up NM_178258 CDNA clone IMAGE:40044751 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like 1, mRNA (cDNA clone MGC:36512 -2.26592 -1.27889 1.98 Up AK164164 IMAGE:5368383) 6.79994 5.814925 1.98 Down NM_029157 Splicing factor 3a, subunit 3 (Sf3a3), mRNA 0.502495 1.485525 1.98 Up NM_009636 AE binding protein 1 (Aebp1), mRNA 4.63684 3.65173 1.98 Down NM_198108 MORN repeat containing 4 (Morn4), mRNA chr5:35975265- 4.17461 5.162235 1.98 Up 35982561_F chr5:35975265-35982561_F ENSMUST00000 RIKEN cDNA 2610039C10 gene (2610039C10Rik), 4.347115 3.358365 1.98 Down 107337 mRNA chr9:56646768- -1.42492 -2.403 1.97 Down 56649068_R chr9:56646768-56649068_R chr4:123572090- -0.60911 -1.584745 1.97 Down 123581365_R chr4:123572090-123581365_R ENSMUST00000 Four and a half LIM domains 1, mRNA (cDNA -1.246475 -2.22359 1.97 Down 064410 clone MGC:32284 IMAGE:5012394) -0.796655 -1.7758 1.97 Down A_55_P2115364 A_55_P2115364 chr2:175543425- -1.366645 -2.347015 1.97 Down 175603300_F chr2:175543425-175603300_F -1.46484 -2.443905 1.97 Down NM_011465 Spectrin alpha 1 (Spna1), mRNA chr11:3538125- -1.29321 -2.268405 1.97 Down 3554450_R chr11:3538125-3554450_R chr6:12062275- -1.8238 -0.842855 1.97 Up 12075800_R chr6:12062275-12075800_R -0.96655 -1.948205 1.97 Down NM_001166645 Zfp882 chr12:74135916- -1.8175 -0.83794 1.97 Up 74142780_F chr12:74135916-74142780_F chr13:53100475- -2.11612 -1.139865 1.97 Up 53113850_R chr13:53100475-53113850_R Zinc finger and SCAN domain containing 4C -0.593895 -1.574585 1.97 Down NM_001013765 (Zscan4c), mRNA -1.297025 -0.31898 1.97 Up AK087605 AK087605 Hormonally upregulated Neu-associated kinase -1.07167 -0.093405 1.97 Up NM_015755 (Hunk), mRNA RIKEN cDNA 6430571L13 gene, mRNA (cDNA 1.033505 2.01191 1.97 Up NM_175486 clone MGC:144888 IMAGE:40107115) 0.39207 -0.5841 1.97 Down A_55_P1960187 A_55_P1960187 Opioid growth factor receptor-like 1, mRNA (cDNA 0.96754 -0.00994 1.97 Down NM_001081079 clone IMAGE:4485439) AlkB, alkylation repair homolog 7 (E. coli) 6.04449 5.069435 1.97 Down NM_025538 (Alkbh7), mRNA Protein C receptor, endothelial, mRNA (cDNA clone 5.42294 4.443095 1.97 Down NM_011171 MGC:41156 IMAGE:1054063) chr6:86776350- 1.4536 0.472455 1.97 Down 86799379_R chr6:86776350-86799379_R Brain mitochondrial carrier protein short-inserted 5.42704 4.4521 1.97 Down NM_011398 form (Tm4sf10) mRNA, complete cds; nuclear gene for mitochondrial product chr15:83181291- -1.815865 -0.84502 1.96 Up 83197750_F chr15:83181291-83197750_F Claudin 6, mRNA (cDNA clone MGC:11572 -1.46978 -2.444105 1.96 Down NM_018777 IMAGE:3594823) -0.797 -1.768905 1.96 Down NM_021355 Fibromodulin (Fmod), mRNA chr2:32950586- -2.152915 -1.18068 1.96 Up 32984936_R chr2:32950586-32984936_R Deoxyribonuclease 1-like 3, mRNA (cDNA clone -0.34177 0.63117 1.96 Up NM_007870 MGC:13854 IMAGE:4160709) chr18:84759512- -0.589675 -1.558545 1.96 Down 84760012_F chr18:84759512-84760012_F Family with sequence similarity 101, member A -2.051235 -1.076775 1.96 Up NM_028443 (Fam101a), mRNA Predicted gene, ENSMUSG00000072602 -1.93291 -0.95861 1.96 Up NM_001098269 (ENSMUSG00000072602), mRNA Kelch repeat and BTB (POZ) domain containing 2, -1.133325 -2.106295 1.96 Down AK030541 mRNA (cDNA clone IMAGE:5347265) chr18:69957420- -2.25319 -1.2797 1.96 Up 69957776_F chr18:69957420-69957776_F chr1:133841295- -0.964995 -1.93284 1.96 Down 133841645_F chr1:133841295-133841645_F Solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 (Slc7a2), -0.546715 0.426455 1.96 Up NM_007514 transcript variant 1, mRNA -0.533525 0.43849 1.96 Up NM_013478 Alpha-2-glycoprotein 1, zinc (Azgp1), mRNA Major facilitator superfamily domain containing 7C -0.646125 0.325525 1.96 Up NM_145447 (Mfsd7c), mRNA Phospholipase C, delta 4 (Plcd4), transcript variant 1.31685 0.34548 1.96 Down NM_148937 2, mRNA 0.272155 1.244905 1.96 Up NM_146007 Collagen, type VI, alpha 2 (Col6a2), mRNA chr9:96632664- 2.087775 3.05626 1.96 Up 96653249_R chr9:96632664-96653249_R Retinol binding protein 1, cellular, mRNA (cDNA 3.808945 2.838595 1.96 Down NM_011254 clone MGC:6258 IMAGE:3498107) Interferon (alpha and beta) receptor 1 (Ifnar1), 2.52661 1.5586 1.96 Down NM_010508 mRNA 4.99309 4.02513 1.96 Down NM_001199494 Ei24 5.06079 4.09124 1.96 Down NM_011454 NK13 (Serpinb6b) 6.97209 6.002535 1.96 Down TC1680794 TC1680794 chr9:56391562- -1.082265 -2.04347 1.95 Down 56392142_F chr9:56391562-56392142_F ENSMUST00000 -0.882645 -1.845545 1.95 Down 172292 Zinc finger protein EZI -1.74493 -0.779735 1.95 Up NM_001011799 Olfactory receptor 453 (Olfr453), mRNA chr5:144517700- -1.40168 -2.36307 1.95 Down 144526071_F chr5:144517700-144526071_F -1.90213 -0.935235 1.95 Up chr9:118059348- chr9:118059348-118079494_F 118079494_F -2.02488 -1.06261 1.95 Up NM_001105066 Vomeronasal 2, receptor 37 (Vmn2r37), mRNA TD and POZ domain containing 2, mRNA (cDNA -0.477225 -1.442555 1.95 Down NM_001007222 clone MGC:176065 IMAGE:9055716) Aldo-keto reductase family 1, member C12, mRNA 1.347925 2.31026 1.95 Up NM_013777 (cDNA clone MGC:13745 IMAGE:4205715) Arginine decarboxylase, mRNA (cDNA clone 2.46484 3.42506 1.95 Up NM_172875 MGC:170601 IMAGE:8861996) Alcohol dehydrogenase 4 (class II), pi polypeptide 0.843505 -0.11801 1.95 Down NM_011996 (Adh4), mRNA Interleukin 17 receptor E (Il17re), transcript variant 3.10684 2.144075 1.95 Down NM_001034031 1, mRNA 4.297485 5.258485 1.95 Up NM_001002927 Enkephalin mRNA Multiple C2 domains, transmembrane 2 (Mctp2), 5.10909 4.149095 1.95 Down NM_001024703 mRNA SNix mRNA, complete cds; nuclear gene for 8.70024 7.734485 1.95 Down NM_009761 mitochondrial product, alternatively spliced 3.560755 2.59594 1.95 Down NM_001242372 Gon4l BCL2-like 13 (apoptosis facilitator) (Bcl2l13), 4.96924 4.009405 1.95 Down NM_153516 nuclear gene encoding mitochondrial protein, mRNA Mitochondrial methionyl-tRNA formyltransferase (Mtfmt), nuclear gene encoding mitochondrial 7.19739 6.233735 1.95 Down NM_027134 protein, mRNA Expressed sequence AI182371, mRNA (cDNA clone -1.540355 -2.494925 1.94 Down NM_178885 MGC:144632 IMAGE:40104352) chr14:26973425- -1.569405 -2.523425 1.94 Down 26986650_R chr14:26973425-26986650_R -1.91779 -2.87042 1.94 Down NM_010340 G-protein-coupled receptor 50 (Gpr50), mRNA -1.643285 -2.599045 1.94 Down AK018486 Proline rich 15 (Prr15), mRNA -1.168815 -2.124375 1.94 Down AK136555 Transcribed locus -1.60189 -0.64857 1.94 Up NR_028424 Gm2176 chr5:123440192- -0.310725 -1.26737 1.94 Down 123451767_R chr5:123440192-123451767_R Zinc finger, DHHC domain containing 23, mRNA 0.695955 1.65263 1.94 Up NM_001007460 (cDNA clone MGC:179097 IMAGE:9054089) Linker for activation of T cells family, member 2, 2.885925 3.84289 1.94 Up NM_020044 mRNA (cDNA clone MGC:6960 IMAGE:3154073) chr11:97457180- 4.59244 3.635505 1.94 Down 97487074_R chr11:97457180-97487074_R Solute carrier family 12 (potassium/chloride transporters), member 8, mRNA (cDNA clone 3.747085 2.793755 1.94 Down NM_134251 MGC:31673 IMAGE:4910321) chr2:153163620- 2.361645 1.40525 1.94 Down 153170845_F chr2:153163620-153170845_F Guanine nucleotide binding protein (G protein), 6.26154 5.307885 1.94 Down NM_025277 gamma 10 (Gng10), mRNA Claudin domain containing 1, mRNA (cDNA clone 8.39184 7.432785 1.94 Down NM_171826 MGC:66639 IMAGE:6414170) chr3:68867193- -1.49658 -2.44725 1.93 Down 68876128_F chr3:68867193-68876128_F chr4:129376440- -1.47547 -2.42342 1.93 Down 129391690_F chr4:129376440-129391690_F -1.413635 -2.36383 1.93 Down NM_146345 Olfactory receptor 1491 (Olfr1491), mRNA -2.406755 -1.458665 1.93 Up AK015163 Transcribed locus -1.92366 -0.974495 1.93 Up NM_001104618 Vomeronasal 2, receptor 5 (Vmn2r5), mRNA -0.45267 -1.397945 1.93 Down NM_001003405 TESP4 Interleukin 1 receptor-like 1 (Il1rl1), transcript -1.95516 -1.007955 1.93 Up NM_010743 variant 2, mRNA -1.51995 -0.575 1.93 Up NR_033584 Gm10280 -0.305885 0.6456 1.93 Up XR_104877 9630013D21Rik -1.2442 -0.29472 1.93 Up TC1610347 TC1610347 chr15:98842850- -0.721285 0.227465 1.93 Up 98853100_R chr15:98842850-98853100_R chr8:41730287- -1.38051 -0.42864 1.93 Up 41746862_R chr8:41730287-41746862_R 0.207975 -0.743895 1.93 Down NM_025658 MS4A4D protein ENSMUST00000 Occludin/ELL domain containing 1, mRNA (cDNA 1.57952 2.52797 1.93 Up 103585 clone MGC:30323 IMAGE:5151818) WD repeat domain 63, mRNA (cDNA clone 1.568795 0.620735 1.93 Down NM_172864 MGC:189892 IMAGE:9007392) Epidermal growth factor receptor pathway substrate 2.546275 1.598265 1.93 Down NM_026146 8 related protein 1 (Eps8R1) 2.58198 3.52902 1.93 Up NM_010740 CDNA clone IMAGE:4912398 2.0685 1.120945 1.93 Down TC1704111 TC1704111 2.60004 3.54689 1.93 Up NM_001204233 Spp1 2.96172 2.016025 1.93 Down TC1633894 TC1633894 chr14:105497388 5.26424 4.31833 1.93 Down -105511063_R chr14:105497388-105511063_R Carcinoembryonic antigen-related cell adhesion molecule 2, mRNA (cDNA clone MGC:18435 1.07971 0.13097 1.93 Down NM_001113368 IMAGE:4241449) 3.805185 2.85605 1.93 Down XR_107060 BC051226 CMAH mRNA for CMP-NeuAc hydroxylase, 3.511645 2.56645 1.93 Down NM_007717 complete cds, major form of alternative splicing Immunoglobulin-like domain containing receptor 1 2.75845 1.811795 1.93 Down NM_134109 (Ildr1), mRNA 3.088045 2.13935 1.93 Down NM_010660 MRNA encoding epidermal keratin subunit 11.88469 10.934685 1.93 Down AK146304 Ribosomal protein S3A (Rps3a), mRNA 5.23694 4.28958 1.93 Down NM_026900 Zfp580 General transcription factor IIF, polypeptide 2, mRNA (cDNA clone MGC:18965 5.33814 4.388455 1.93 Down NM_026816 IMAGE:3986466) -0.974225 -1.916145 1.92 Down NM_177049 Junctophilin 4 (Jph4), transcript variant b, mRNA -0.538675 -1.476625 1.92 Down chr15:73227424- chr15:73227424-73257474_R 73257474_R WNT1 inducible signaling pathway protein 2, ENSMUST00000 mRNA (cDNA clone MGC:41105 -2.184425 -1.24089 1.92 Up 103320 IMAGE:1067632) Nuclear receptor coactivator 7, mRNA (cDNA clone -0.5323 -1.475625 1.92 Down NM_172495 MGC:176111 IMAGE:9055762) -1.1088 -2.051745 1.92 Down NM_001172074 3110009E18Rik -1.468145 -0.52591 1.92 Up NM_009355 Testicular serine protease 1 (Tesp1), mRNA Frizzled homolog 5 (Drosophila) (Fzd5), transcript -0.64604 -1.590845 1.92 Down NM_022721 variant 1, mRNA Interleukin 20 receptor, alpha, mRNA (cDNA clone 0.81563 1.757195 1.92 Up NM_172786 MGC:67678 IMAGE:5033177) Eosinophil-associated, ribonuclease A family, 0.954695 1.898805 1.92 Up NM_053113 member 11 (Ear11), mRNA 3.321855 4.265365 1.92 Up NM_027127 Glutathione peroxidase 8 (putative) (Gpx8), mRNA F-box protein 17, mRNA (cDNA clone MGC:31493 1.00547 1.947385 1.92 Up NM_015796 IMAGE:4486850) 2.987165 3.927315 1.92 Up AK031397 Hps1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 6.91389 7.852585 1.92 Up NM_009177 (St3gal1), mRNA Tryptophanyl tRNA synthetase 2 (mitochondrial) (Wars2), nuclear gene encoding mitochondrial 2.240105 1.29736 1.92 Down NM_027462 protein, mRNA Cathepsin D, mRNA (cDNA clone 4.63374 5.573885 1.92 Up NM_009983 IMAGE:4500905) 3.99165 3.05039 1.92 Down AK018252 Transcribed locus RIKEN cDNA 8430410K20 gene (8430410K20Rik), 5.30159 4.357245 1.92 Down NM_145609 mRNA Leukocyte receptor cluster (LRC) member 8, mRNA 5.96759 5.02381 1.92 Down NM_172736 (cDNA clone MGC:66549 IMAGE:6407146) Neuron specific gene family member 2, mRNA 6.55054 5.611085 1.92 Down NM_008741 (cDNA clone MGC:25346 IMAGE:4527900) Heparin-binding EGF-like growth factor (Hbegf), 2.665925 3.604065 1.92 Up NM_010415 mRNA Predicted gene, OTTMUSG00000010747, mRNA -1.727385 -2.663075 1.91 Down NM_001081248 (cDNA clone MGC:183895 IMAGE:9087895) ENSMUST00000 -1.486605 -2.42152 1.91 Down 089534 ENSMUST00000089534 -2.11463 -1.18261 1.91 Up NR_001583 Speer9-ps1 PREDICTED: Mus musculus hypothetical protein -1.22949 -2.164065 1.91 Down NAP106674-1 LOC100040572 (LOC100040572), mRNA Trace amine-associated receptor 5, mRNA (cDNA -0.313955 -1.24559 1.91 Down NM_001009574 clone MGC:170815 IMAGE:8862210) -2.319565 -1.389535 1.91 Up NM_201530 Sycp3 like Y-linked (Sly), mRNA -0.75636 -1.691685 1.91 Down NM_177373 Liprin-alpha 2 (ppfia2) -0.32157 -1.258515 1.91 Down NM_138650 Diacylglycerol kinase, gamma (Dgkg), mRNA chr16:9249688- -0.77501 -1.710865 1.91 Down 9275013_R chr16:9249688-9275013_R chr9:58301467- -2.072085 -1.13572 1.91 Up 58323783_R chr9:58301467-58323783_R -1.53996 -0.603475 1.91 Up NM_001105057 Vomeronasal 2, receptor 60 (Vmn2r60), mRNA PREDICTED: Mus musculus RIKEN cDNA -0.99692 -1.930805 1.91 Down AK015266 4930431F10 gene (4930431F10Rik), mRNA chr8:67542714- -1.322475 -0.387655 1.91 Up 67561694_F chr8:67542714-67561694_F -1.465055 -0.529175 1.91 Up A_55_P2166326 Ring finger protein 215 (Rnf215), mRNA Protein tyrosine phosphatase, receptor type Z, ENSMUST00000 polypeptide 1, mRNA (cDNA clone 0.296245 1.229695 1.91 Up 152141 IMAGE:3590815) Peroxisome proliferator activated receptor gamma, mRNA (cDNA clone MGC:18439 3.102725 4.03982 1.91 Up NM_011146 IMAGE:4191539) chr16:84707202- 4.3648 3.42818 1.91 Down 84707748_F chr16:84707202-84707748_F A disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 14, mRNA 2.562445 3.499425 1.91 Up NM_001081127 (cDNA clone MGC:189783 I 1.262945 0.3275 1.91 Down NM_134159 IL-17RC Na+/H+ exchanger domain containing 2, mRNA 5.03464 4.10389 1.91 Down NM_178877 (cDNA clone MGC:107160 IMAGE:30503721) GPI-anchored membrane protein CDw108 precursor 7.17719 6.242085 1.91 Down NM_011352 (CDw108) Purinergic receptor P2Y, G-protein coupled, 5, mRNA (cDNA clone MGC:175829 6.68139 5.751285 1.91 Down NM_175116 IMAGE:40131245) 3.722935 4.657585 1.91 Up NM_001082546 CDNA sequence BC100530 (BC100530), mRNA 3.01187 2.075795 1.91 Down A_55_P2092286 A_55_P2092286 Ring finger protein 7, mRNA (cDNA clone 8.22079 7.284135 1.91 Down NM_011279 IMAGE:4194107) 3.63243 2.69899 1.91 Down A_55_P2133187 LUC7-like 2 (S. cerevisiae) (Luc7l2), mRNA Solute carrier family 7 (cationic amino acid 2.933695 3.869915 1.91 Up NM_007515 transporter, y+ system), member 3 (Slc7a3), mRNA Solute carrier family 44, member 5 (Slc44a5), -1.555275 -2.484695 1.9 Down NM_001081263 mRNA -0.39594 0.5272 1.9 Up NM_022004 Plp mRNA for PLM-like protein -1.936155 -1.01274 1.9 Up NM_153803 Galactosidase, beta 1-like 2 (Glb1l2), mRNA G protein-coupled receptor kinase 4 (Grk4), -0.70989 -1.63779 1.9 Down NM_001080743 transcript variant 1, mRNA chr1:85117750- -1.742315 -2.670365 1.9 Down 85129200_F chr1:85117750-85129200_F chr16:3111550- -1.144035 -0.22179 1.9 Up 3130500_R chr16:3111550-3130500_R chr13:70745306- -0.703005 -1.628615 1.9 Down 70837331_F chr13:70745306-70837331_F Taste receptor, type 2, member 126, mRNA (cDNA -1.362235 -2.288015 1.9 Down NM_207028 clone MGC:144349 IMAGE:40101187) -0.120235 -1.049365 1.9 Down AK078387 CDNA clone IMAGE:40053282 -2.1356 -1.20666 1.9 Up NM_001199331 LOC100040022 chr5:92563184- -1.24764 -2.170905 1.9 Down 92566678_R chr5:92563184-92566678_R Kinase suppressor of ras 2 (Ksr2), transcript variant -1.24145 -2.16635 1.9 Down NM_001034873 1, mRNA -1.718595 -0.791495 1.9 Up NM_008817 Peg3 mRNA for zinc finger protein chr5:137392195- -0.73028 -1.65987 1.9 Down 137426421_F chr5:137392195-137426421_F chr1:115829055- -1.641035 -0.71833 1.9 Up 115854155_R chr1:115829055-115854155_R chr6:126502067- -0.85075 -1.777 1.9 Down 126507755_F chr6:126502067-126507755_F Fc receptor, IgG, alpha chain transporter, mRNA 0.64844 1.57625 1.9 Up NM_010189 (cDNA clone MGC:6014 IMAGE:3485649) chr4:147105275- 0.193285 1.11604 1.9 Up 147171025_F chr4:147105275-147171025_F chr9:96632664- 2.618015 3.546315 1.9 Up 96653249_R chr9:96632664-96653249_R PDZ and LIM domain 4, mRNA (cDNA clone 2.973575 3.89594 1.9 Up NM_019417 MGC:41095 IMAGE:5144166) RIKEN cDNA 1700041C02 gene (1700041C02Rik), 1.32426 0.394895 1.9 Down NM_029286 mRNA ENSMUST00000 2.11183 1.18575 1.9 Down 141786 ENSMUST00000141786 Purinergic receptor P2Y, G-protein coupled, 5, mRNA (cDNA clone MGC:175829 7.55879 6.632935 1.9 Down AK032901 IMAGE:40131245) 6.98899 6.059935 1.9 Down NM_139198 C15 protein Myeloid leukemia factor 1, mRNA (cDNA clone 2.22816 1.3043 1.9 Down NM_010801 MGC:41163 IMAGE:1495721) chr8:41475940- 1.3462 0.42328 1.9 Down 41476460_F chr8:41475940-41476460_F -1.582335 -2.50036 1.89 Down XM_003084614 LOC319689 ENSMUST00000 -1.54261 -2.459915 1.89 Down 113284 Tcfeb chr5:88995039- -1.96559 -1.04521 1.89 Up 89009064_F chr5:88995039-89009064_F chr18:63525907- -2.35788 -1.442515 1.89 Up 63526504_R chr18:63525907-63526504_R chr14:21621875- -0.61142 -1.532415 1.89 Down 21638625_R chr14:21621875-21638625_R Bone-restricted interferon induced transmembrane -1.015115 -0.10043 1.89 Up NM_053088 protein-like protein (Bril) chr8:27259077- -1.711005 -0.79142 1.89 Up 27268252_F chr8:27259077-27268252_F -2.28981 -1.37359 1.89 Up AK014916 Transcribed locus chr3:65460193- -0.26184 -1.180515 1.89 Down 65460769_R chr3:65460193-65460769_R -0.370445 -1.2883 1.89 Down NM_144919 Histone deacetylase 11 (Hdac11), mRNA chr12:4581550- -2.09161 -1.17016 1.89 Up 4599600_F chr12:4581550-4599600_F chr1:138570107- -0.92103 -1.8418 1.89 Down 138632310_F chr1:138570107-138632310_F -2.246965 -1.33017 1.89 Up AU042950 Transcribed locus -1.456755 -0.54121 1.89 Up NR_027858 Nlrp1c-ps 0.851995 1.7695 1.89 Up NM_026547 1520402A15Rik RIKEN cDNA 9830134C10 gene, mRNA (cDNA 0.52816 1.445835 1.89 Up NM_001002786 clone MGC:170999 IMAGE:8862394) chr19:12079745- 0.23255 -0.68205 1.89 Down 12088620_R chr19:12079745-12088620_R 2.08819 1.16777 1.89 Down NR_015506 4833418N02Rik Transmembrane protein 71, mRNA (cDNA clone 0.34739 -0.56929 1.89 Down NM_172514 MGC:143747 IMAGE:40092864) 3.597555 2.678425 1.89 Down NM_147221 GLIS family zinc finger 1 (Glis1), mRNA Apolipoprotein B48 receptor, mRNA (cDNA clone 3.055355 3.973965 1.89 Up NM_138310 MGC:28748 IMAGE:4482457) 4.55274 3.63495 1.89 Down XR_105075 Zfp626 Phospholipase A2, group IVB (cytosolic) (Pla2g4b), 5.94329 5.023365 1.89 Down NM_145378 mRNA Receptor-like tyrosine kinase, mRNA (cDNA clone 3.683175 2.76425 1.89 Down NM_013649 MGC:40871 IMAGE:5370100) 7.04299 6.123385 1.89 Down NM_025659 ABI gene family, member 3 (Abi3), mRNA Von Willebrand factor A domain containing 5A, 4.34351 3.426765 1.89 Down NM_172767 mRNA (cDNA clone MGC:6690 IMAGE:3582797) chr3:87575891- -1.511875 -2.421805 1.88 Down 87576343_F chr3:87575891-87576343_F chr3:48896525- -1.50189 -2.410605 1.88 Down 48994125_F chr3:48896525-48994125_F chr18:35985999- -1.206945 -2.117255 1.88 Down 35986376_R chr18:35985999-35986376_R -1.52654 -2.438455 1.88 Down NM_001011866 Olfactory receptor 309 (Olfr309), mRNA chr1:20669157- -1.96231 -1.05505 1.88 Up 20672643_F chr1:20669157-20672643_F Fibroblast activation protein, mRNA (cDNA clone -0.536535 -1.44864 1.88 Down NM_007986 MGC:29100 IMAGE:5028579) -1.69603 -2.606555 1.88 Down NM_054068 Transcription factor VSX1 (Vsx1) -1.17507 -2.085395 1.88 Down NM_033603 Amnionless (Amn), mRNA Peroxisome proliferator activated receptor alpha, ENSMUST00000 mRNA (cDNA clone MGC:18607 -0.48833 -1.400345 1.88 Down 102575 IMAGE:4222384) -1.793405 -0.88208 1.88 Up NM_001101603 Predicted gene, EG667063 (EG667063), mRNA chr12:88235624- -1.298375 -0.3869 1.88 Up 88264465_F chr12:88235624-88264465_F chr5:107503800- -1.946385 -1.03409 1.88 Up 107515575_F chr5:107503800-107515575_F Protein phosphatase, EF hand calcium-binding domain 2, mRNA (cDNA clone MGC:38671 -0.82673 -1.739795 1.88 Down NM_011148 IMAGE:5356685) chr18:32389816- -0.694375 -1.60429 1.88 Down 32394927_R chr18:32389816-32394927_R chr9:58301467- -0.564735 0.34256 1.88 Up 58323783_F chr9:58301467-58323783_F Calcium channel, voltage-dependent, T type, alpha -0.85869 -1.765695 1.88 Down A_55_P1986608 1H subunit (Cacna1h), mRNA -0.35942 -1.27193 1.88 Down XM_003084553 Gm10723 0.31188 -0.599295 1.88 Down NM_008179 G1 to S phase transition 2 (Gspt2), mRNA Ajuba, mRNA (cDNA clone MGC:13721 0.851755 1.76027 1.88 Up NM_010590 IMAGE:4187633) 1.17065 0.260405 1.88 Down NM_017469 Soluble guanylyl cyclase beta 1 subunit ENSMUST00000 Transportin 1, mRNA (cDNA clone 1.605355 2.51608 1.88 Up 069592 IMAGE:4954721) 2.5734 3.481245 1.88 Up XR_002334 Lrrc31 Kinesin family member C3, mRNA (cDNA clone 2.147935 1.23502 1.88 Down NM_010631 IMAGE:5008217) Guanine monphosphate synthetase, mRNA (cDNA 1.45417 0.542545 1.88 Down NM_001033300 clone IMAGE:4950527) Methionyl aminopeptidase 1, mRNA (cDNA clone 4.54044 3.63038 1.88 Down NM_175224 IMAGE:5359840) Procollagen lysine, 2-oxoglutarate 5-dioxygenase 2, mRNA (cDNA clone MGC:29312 5.81229 4.899585 1.88 Down NM_011961 IMAGE:5007509) Aldehyde dehydrogenase 2, mitochondrial, mRNA 3.912195 4.82422 1.88 Up NM_009656 (cDNA clone MGC:6764 IMAGE:3600875) 4.61464 3.70321 1.88 Down NAP065441-1 Gene model 879, (NCBI) (Gm879), mRNA RIKEN cDNA 2010005H15 gene (2010005H15Rik), 5.69349 6.605085 1.88 Up NM_029733 mRNA RIKEN cDNA 1300007F04 gene (1300007F04Rik), 2.524325 1.613215 1.88 Down NM_026185 mRNA Partial Rabip4 gene for FYVE-finger containing 4.07059 3.16288 1.88 Down NM_172557 protein Expressed sequence AI662250, mRNA (cDNA clone 3.59926 2.690515 1.88 Down NM_178926 IMAGE:5690401) PREDICTED: Mus musculus predicted gene, -0.45579 -1.35603 1.87 Down AK142189 EG626231 (EG626231), mRNA RIKEN cDNA 9030409G11 gene (9030409G11Rik), -1.27754 -2.18316 1.87 Down NM_001109685 transcript variant 1, mRNA -1.74483 -0.839445 1.87 Up NM_001162965 Sgsm1 PREDICTED: Mus musculus RIKEN cDNA -1.513725 -2.420255 1.87 Down AK020710 A230103O09 gene (A230103O09Rik), mRNA ENSMUST00000 Tetratricopeptide repeat domain 22, mRNA (cDNA -0.584285 -1.490805 1.87 Down 039080 clone MGC:163793 IMAGE:40130439) -0.17892 -1.0798 1.87 Down XR_105712 A330009N23Rik -1.15152 -0.250185 1.87 Up NM_146632 Olfactory receptor 116 (Olfr116), mRNA Myosin light chain, regulatory B, mRNA (cDNA -1.43339 -0.530925 1.87 Up A_55_P2139426 clone MGC:25448 IMAGE:4218748) ENSMUST00000 -0.471835 0.431635 1.87 Up 037976 Stereocilin (Strc), mRNA Riken cDNA E230025N22 gene (E230025N22Rik), -0.87247 -1.77922 1.87 Down NM_172831 mRNA chr4:129376440- -0.258625 -1.165475 1.87 Down 129391690_F chr4:129376440-129391690_F chr9:106170918- -1.15644 -0.25507 1.87 Up 106177894_R chr9:106170918-106177894_R 0.259845 1.161885 1.87 Up NM_172911 MFLJ00269 protein chr9:68349343- 0.536575 -0.36355 1.87 Down 68411643_F chr9:68349343-68411643_F Family with sequence similarity 171, member B, 1.854895 0.9487 1.87 Down NM_175514 mRNA (cDNA clone IMAGE:4501762) 8.32384 9.227835 1.87 Up NM_007899 Extracellular matrix protein 1 (Ecm1), mRNA 2.455005 1.552235 1.87 Down NR_028298 2610306M01Rik Methylthioadenosine phosphorylase, mRNA (cDNA 2.82006 1.920175 1.87 Down NM_024433 clone MGC:6590 IMAGE:3485422) Trichorhinophalangeal syndrome I (human), mRNA 4.1358 3.236315 1.87 Down NM_032000 (cDNA clone MGC:46754 IMAGE:4951294) 4.26663 3.36663 1.87 Down NM_009331 Transcription factor 7, T-cell specific (Tcf7), mRNA 4.73714 3.835575 1.87 Down NM_008354 Interleukin 12 receptor, beta 2 (Il12rb2), mRNA ENSMUST00000 -0.661265 -1.554585 1.86 Down 039118 Zic5 chr11:82588507- -1.3873 -2.28616 1.86 Down 82594501_F chr11:82588507-82594501_F chr5:52461266- -1.62346 -2.515325 1.86 Down 52541416_F chr5:52461266-52541416_F chr13:94069868- -0.8844 -1.77757 1.86 Down 94070007_R chr13:94069868-94070007_R chr16:50752452- -1.90512 -2.796735 1.86 Down 50753589_F chr16:50752452-50753589_F chr14:22267795- -1.917895 -1.021315 1.86 Up 22319045_R chr14:22267795-22319045_R Keratin 19, mRNA (cDNA clone MGC:25344 -1.871465 -0.972615 1.86 Up NM_008471 IMAGE:2655016) chr7:71093563- -0.75311 -1.64739 1.86 Down 71095094_F chr7:71093563-71095094_F Ankyrin repeat domain 26, mRNA (cDNA clone -0.20326 0.69566 1.86 Up A_55_P2134725 IMAGE:3482234) ENSMUST00000 RIKEN cDNA 6330416L07 gene, mRNA (cDNA -1.73946 -0.845855 1.86 Up 115549 clone IMAGE:4224834) -0.87919 -1.775685 1.86 Down NM_028121 ADP-dependent glucokinase (Adpgk), mRNA -1.796855 -0.898305 1.86 Up NM_011382 AREC3 Predicted gene, EG574083, mRNA (cDNA clone -1.721965 -0.825575 1.86 Up NM_001025353 MGC:170791 IMAGE:8862186) -1.104035 -2.00002 1.86 Down NM_001164286 Gm5415 -1.03309 -0.137565 1.86 Up NM_198111 A-kinase anchoring protein alpha (Akapalpha) Glutathione peroxidase 7, mRNA (cDNA clone 0.779235 1.676135 1.86 Up NM_024198 MGC:6581 IMAGE:3483448) 0.789175 1.68235 1.86 Up NM_010136 Tbr2 0.14672 -0.750505 1.86 Down NM_011617 CD70 antigen (Cd70), mRNA Nuclear receptor subfamily 4, group A, member 2 1.771545 0.873925 1.86 Down NM_013613 (Nr4a2), transcript variant 1, mRNA chr10:96082444- 2.702925 1.80901 1.86 Down 96096696_R chr10:96082444-96096696_R 3.15789 2.25931 1.86 Down NM_013464 Strain A/J aryl-hydrocarbon receptor (Ahr) chr15:33966641- 2.474905 1.57871 1.86 Down 34004891_R chr15:33966641-34004891_R chr4:116790373- 0.444145 -0.447465 1.86 Down 116797823_F chr4:116790373-116797823_F ADP-ribosylation factor GTPase activating protein 2, mRNA (cDNA clone MGC:7383 2.450885 3.34956 1.86 Up NM_023854 IMAGE:3487811) 8.57124 7.678185 1.86 Down NM_013464 Strain A/J aryl-hydrocarbon receptor (Ahr) 3-oxoacyl-ACP synthase, mitochondrial, mRNA 2.46593 1.569175 1.86 Down NM_027695 (cDNA clone MGC:144806 IMAGE:40106281) Solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25, mRNA (cDNA clone 3.96096 3.06823 1.86 Down NM_146118 MGC:47196 IMAGE:5368306) 5.09889 5.994035 1.86 Up NM_030887 Jdp2 mRNA for jun dimerization protein 2 Centrobin, centrosomal BRCA2 interacting protein, mRNA (cDNA clone MGC:66579 4.73469 3.841205 1.86 Down NM_172560 IMAGE:6817014) 7.95284 7.054335 1.86 Down NM_016753 Latexin (Lxn), mRNA 5.42934 4.535475 1.86 Down NM_173781 Rab6B 6.32554 5.434085 1.86 Down NM_007961 Ets variant gene 6 (TEL oncogene) (Etv6), mRNA REX2, RNA exonuclease 2 homolog (S. cerevisiae) 7.18054 6.288435 1.86 Down NM_024233 (Rexo2), mRNA Cas scaffolding protein family member 4 (Cass4), -1.14483 -0.254555 1.85 Up NM_001080820 transcript variant 2, mRNA chr17:88225376- -1.548075 -2.434615 1.85 Down 88238756_F chr17:88225376-88238756_F -1.51114 -2.39755 1.85 Down AK016122 Transcribed locus -0.825225 -1.71621 1.85 Down NM_001097644 Cyclin Y-like 1 (Ccnyl1), mRNA Kallikrein 1-related petidase b26, mRNA (cDNA -1.77715 -0.890965 1.85 Up NM_010644 clone MGC:18572 IMAGE:4167696) Transmembrane and coiled-coil domains 1, mRNA -0.18676 -1.075105 1.85 Down NM_001039483 (cDNA clone MGC:30289 IMAGE:5009960) chr17:3198868- -1.449615 -2.33492 1.85 Down 3394643_F chr17:3198868-3394643_F chr8:35650475- -0.53423 -1.42082 1.85 Down 35664200_F chr8:35650475-35664200_F -0.24531 -1.134735 1.85 Down XM_135559 LOC236220 chr3:41143423- -1.30959 -0.41977 1.85 Up 41359623_F chr3:41143423-41359623_F -1.177035 -0.29122 1.85 Up TC1623478 TC1623478 ENSMUST00000 MARVEL (membrane-associating) domain -0.462255 0.42422 1.85 Up 103598 containing 3 (Marveld3), transcript variant 1, mRNA chr8:35652473- 0.373225 1.264275 1.85 Up 35703370_R chr8:35652473-35703370_R 3.354405 4.239445 1.85 Up NM_198664 TBC1 domain family, member 2 (Tbc1d2), mRNA chr16:84707202- 4.10016 3.212655 1.85 Down 84707748_F chr16:84707202-84707748_F 3.753715 4.640235 1.85 Up NR_037980 LOC100047133 chr16:84702353- 5.13044 4.243645 1.85 Down 84710928_R chr16:84702353-84710928_R chr3:92065425- 3.35187 2.467425 1.85 Down 92086850_F chr3:92065425-92086850_F Solute carrier family 25, member 27 (Slc25a27), 1.932925 1.04269 1.85 Down NM_028711 nuclear gene encoding mitochondrial protein, mRNA 4.83809 3.946805 1.85 Down A_55_P2148935 A_55_P2148935 CD86 antigen, mRNA (cDNA clone MGC:18471 5.32729 4.439275 1.85 Down NM_019388 IMAGE:4008635) Kinesin family member 2A, mRNA (cDNA clone 5.85759 4.972505 1.85 Down NM_008442 MGC:11609 IMAGE:3152883) 5.87849 6.762585 1.85 Up NM_001005421 Dendritic-cell specific protein Crea7 (Crea7) Similar to Eukaryotic translation initiation factor 1 (eIF1) (Protein translation factor SUI1 homolog) 8.41559 7.527335 1.85 Down NM_001100618 (LOC100043225), mRNA 9.38729 8.503635 1.85 Down XM_001475319 Gm6570 Family with sequence similarity 108, member C 6.77759 5.889385 1.85 Down NM_133722 (Fam108c), mRNA 5.41004 4.52226 1.85 Down NM_009083 Ribosomal protein L30 (Rpl30), mRNA Trichorhinophalangeal syndrome I (human), mRNA 3.394255 2.50328 1.85 Down NM_032000 (cDNA clone MGC:46754 IMAGE:4951294) chr6:37630192- -1.49029 -0.61029 1.84 Up 37682692_F chr6:37630192-37682692_F -1.209105 -2.08778 1.84 Down NM_007866 Delta-like 3 (Drosophila) (Dll3), mRNA Elongation factor RNA polymerase II-like 3 (Ell3), -0.51636 -1.39586 1.84 Down NM_145973 mRNA -0.94419 -1.82019 1.84 Down AK149124 Gm10675 POU domain, class 5, transcription factor 1 -1.90763 -1.027455 1.84 Up NM_013633 (Pou5f1), mRNA Leucine-rich repeat-containing G protein-coupled -1.74818 -2.62858 1.84 Down AK040883 receptor 6, mRNA (cDNA clone IMAGE:3982506) -1.556005 -2.437205 1.84 Down NM_010808 Matrix metallopeptidase 24 (Mmp24), mRNA -2.47403 -1.59735 1.84 Up NM_133660 Esterase 22 (Es22), mRNA chr6:128397450- -2.01666 -1.13304 1.84 Up 128398394_F chr6:128397450-128398394_F -1.040135 -1.919875 1.84 Down NM_001199956 Gm9839 DENN/MADD domain containing 2A, mRNA -1.966105 -1.088605 1.84 Up NM_172477 (cDNA clone MGC:183710 IMAGE:9087710) chr1:40113561- -1.234795 -0.351775 1.84 Up 40113777_R chr1:40113561-40113777_R COX15 homolog, cytochrome c oxidase assembly protein (yeast) (Cox15), nuclear gene encoding -1.432725 -0.55584 1.84 Up NAP057266-1 mitochondrial protein, mRNA ENSMUST00000 Protein inhibitor of activated STAT 1 (Pias1), -1.8133 -0.93385 1.84 Up 057722 mRNA -1.21887 -0.342655 1.84 Up NM_177660 Zbtb10 A disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16, mRNA -1.3939 -0.51636 1.84 Up NM_172053 (cDNA clone MGC:37086 IM chr9:78107225- -1.02539 -0.14475 1.84 Up 78118850_R chr9:78107225-78118850_R Wolf-Hirschhorn syndrome candidate 1 (human), 0.64052 -0.23969 1.84 Down A_55_P2113539 mRNA (cDNA clone IMAGE:9007381) RIKEN cDNA 1110036O03 gene, mRNA (cDNA 3.03719 2.155255 1.84 Down NM_176830 clone MGC:25554 IMAGE:3968941) Glycerophosphodiester phosphodiesterase domain 2.999455 2.1228 1.84 Down NM_025638 containing 1 (Gdpd1), mRNA ENSMUST00000 2.169265 1.293235 1.84 Down 098544 Strain C57BL/6J skint 9 isoform a precursor (Skint9) Tryptophanyl-tRNA synthetase, mRNA (cDNA 3.97705 3.09399 1.84 Down NM_011710 clone MGC:6537 IMAGE:2654231) HECT domain containing 2, mRNA (cDNA clone 3.544335 2.66234 1.84 Down NM_172637 MGC:178371 IMAGE:9053363) Fc receptor-like 1 (Fcrl1), transcript variant 1, 2.485725 1.60362 1.84 Down NM_178165 mRNA 6.82049 7.699135 1.84 Up XR_106152 LOC100503910 Proline rich 7 (synaptic), mRNA (cDNA clone 4.79499 3.914595 1.84 Down NM_001030296 MGC:170483 IMAGE:8861878) Glucocorticoid receptor DNA binding factor 1, mRNA (cDNA clone MGC:171088 5.60914 4.731175 1.84 Down NM_172739 IMAGE:8862483) Heterogeneous nuclear ribonucleoprotein U-like 1 6.50294 5.625235 1.84 Down NM_144922 (Hnrnpul1), transcript variant 1, mRNA REX2, RNA exonuclease 2 homolog (S. cerevisiae) 6.99889 6.119635 1.84 Down NM_024233 (Rexo2), mRNA Tyrosine 3-monooxygenase/tryptophan 5- monooxygenase activation protein, theta polypeptide 8.50199 7.624885 1.84 Down NM_011739 (Ywhaq), mRNA -1.281285 -0.408485 1.83 Up lincP21 lincP21 Killer cell lectin-like receptor family I member 2, ENSMUST00000 mRNA (cDNA clone MGC:164037 -1.48566 -2.35414 1.83 Down 123037 IMAGE:40130683) chr9:113648970- -1.59168 -2.462625 1.83 Down 113715170_R chr9:113648970-113715170_R -1.57933 -2.45403 1.83 Down NM_027391 Iodotyrosine deiodinase (Iyd), mRNA Complement component 1, q subcomponent-like 4, mRNA (cDNA clone MGC:182152 -1.56093 -2.434055 1.83 Down NM_001024702 IMAGE:9056046) ENSMUST00000 Reproductive homeobox 4A, mRNA (cDNA clone -1.275 -2.143845 1.83 Down 145869 MGC:178948 IMAGE:9053940) Potassium inwardly-rectifying channel, subfamily J, member 8, mRNA (cDNA clone MGC:5890 -1.420325 -0.55016 1.83 Up NM_008428 IMAGE:3490123) -2.35798 -1.48784 1.83 Up NM_023709 Calpain 9 (Capn9), mRNA chr1:134867906- -1.494385 -2.36587 1.83 Down 134885481_F chr1:134867906-134885481_F ENSMUST00000 Expressed sequence AW209491, mRNA (cDNA -1.32365 -2.19353 1.83 Down 088296 clone MGC:38935 IMAGE:5362794) chr4:11102287- -1.48527 -2.35328 1.83 Down 11118421_R chr4:11102287-11118421_R chr10:16603950- -1.358525 -0.485265 1.83 Up 16794075_F chr10:16603950-16794075_F -0.88672 -1.75794 1.83 Down AK034541 CDNA clone IMAGE:5711158 ENSMUST00000 -0.55706 -1.42589 1.83 Down 097750 ENSMUST00000097750 chr10:57549604- -0.737145 0.131045 1.83 Up 57549956_R chr10:57549604-57549956_R -1.805685 -0.93221 1.83 Up NM_054038 UGRP1A chr7:118248833- -2.312115 -1.43758 1.83 Up 118267766_F chr7:118248833-118267766_F -0.696165 -1.56653 1.83 Down XR_035095 4930594M22Rik Cardiotrophin 1, mRNA (cDNA clone MGC:36108 -0.509365 -1.37938 1.83 Down NM_007795 IMAGE:4986446) -0.82184 0.049785 1.83 Up NM_011532 T-box 1 (Tbx1), mRNA PREDICTED: Mus musculus predicted gene, -0.97848 -0.10559 1.83 Up AK144087 EG622523 (EG622523), mRNA 1.644535 2.514215 1.83 Up NM_030707 IFGP2 chr3:19179899- 1.475915 0.606535 1.83 Down 19216399_F chr3:19179899-19216399_F ENSMUST00000 0.680405 -0.192275 1.83 Down 124404 CDNA clone IMAGE:4501462 chr4:21683562- 0.36774 -0.507285 1.83 Down 21694344_F chr4:21683562-21694344_F 1.26145 2.129565 1.83 Up NM_028971 4933430H15Rik 4.15916 3.290775 1.83 Down NM_016908 Synaptotagmin V (Syt5), mRNA 3.809285 2.939385 1.83 Down NM_053255 ElaC homolog 1 (E. coli) (Elac1), mRNA Cerebellar degeneration-related protein 2-like, mRNA (cDNA clone MGC:178379 2.955485 2.07992 1.83 Down NM_001080929 IMAGE:9053371) chr1:81632600- 2.73337 1.86262 1.83 Down 81644175_F chr1:81632600-81644175_F Chitobiase, di-N-acetyl-, mRNA (cDNA clone 1.547625 0.67859 1.83 Down NM_028836 IMAGE:4038549) Phytanoyl-CoA dioxygenase domain containing 1, mRNA (cDNA clone MGC:178922 6.90224 7.772735 1.83 Up NM_172267 IMAGE:9053914) 4.71099 3.836315 1.83 Down NM_001033528 Usp36 1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta), mRNA 7.79224 6.919935 1.83 Down NM_018743 (cDNA clone MGC:28958 IMAG 0.792465 1.66545 1.83 Up A_55_P2418621 Transcribed locus Colony stimulating factor 1 (macrophage), mRNA 3.461865 2.59096 1.83 Down NM_007778 (cDNA clone IMAGE:5342906) Vesicle-associated membrane protein, associated 6.99399 6.124585 1.83 Down NM_019806 protein B and C (Vapb), mRNA Zinc finger protein 661 (Zfp661), transcript variant 3.31726 2.44753 1.83 Down NM_001111029 2, mRNA Coiled-coil domain containing 9, mRNA (cDNA 2.267115 3.138145 1.83 Up NM_172297 clone MGC:27654 IMAGE:4527178) 0.388925 -0.48186 1.83 Down XR_106204 2210008F06Rik 7.48629 6.616785 1.83 Down NM_001198984 Tcof1 chr5:15033568- -0.78803 0.07322 1.82 Up 15033987_F chr5:15033568-15033987_F chr16:64758224- -1.0776 -1.93983 1.82 Down 64765700_R chr16:64758224-64765700_R chr2:60581618- -1.875475 -1.00927 1.82 Up 60589907_F chr2:60581618-60589907_F chr3:35782698- -1.91058 -1.046455 1.82 Up 35789748_F chr3:35782698-35789748_F Sperm associated antigen 8, mRNA (cDNA clone -2.00205 -1.13745 1.82 Up NM_001007463 MGC:183779 IMAGE:9087779) -1.610845 -0.74708 1.82 Up C76614 Transcribed locus Sorbin and SH3 domain containing 3, mRNA -0.31588 0.54611 1.82 Up NM_011366 (cDNA clone MGC:31726 IMAGE:4920799) ENSMUST00000 -1.168685 -2.02964 1.82 Down 039987 P73 alpha protein (P73 gene) C-type lectin domain family 4, member b1 -1.52684 -0.66454 1.82 Up NM_027218 (Clec4b1), mRNA -0.94639 -1.81124 1.82 Down AK028457 Transcribed locus Solute carrier family 5 (sodium/glucose -1.357155 -2.21991 1.82 Down NM_133254 cotransporter), member 2 (Slc5a2), mRNA chr2:75484041- -1.851975 -0.984435 1.82 Up 75484815_R chr2:75484041-75484815_R chr13:49488457- -1.189605 -2.05189 1.82 Down 49493732_F chr13:49488457-49493732_F ENSMUST00000 DNA-damage-inducible transcript 4-like, mRNA -1.569035 -0.704205 1.82 Up 090180 (cDNA clone IMAGE:5254530) chr4:105035450- -1.07028 -0.208665 1.82 Up 105059250_F chr4:105035450-105059250_F Transcribed locus, strongly similar to ENSMUST00000 XP_001479311.1 PREDICTED: hypothetical protein -1.334995 -2.20161 1.82 Down 086681 [Mus musculus] -0.626615 0.236205 1.82 Up NM_008795 PCTAIRE-motif protein kinase 3 (Pctk3), mRNA Collagen, type VI, alpha 1, mRNA (cDNA clone -0.381445 0.48442 1.82 Up NM_009933 IMAGE:3488924) -1.439955 -0.578495 1.82 Up lincP21 lincP21 -2.10645 -1.24204 1.82 Up AK016233 Transcribed locus -1.773295 -0.910805 1.82 Up AK086454 D930030D11Rik Disrupted-in-schizophrenia-1 (Disc1) mRNA, -0.97502 -1.84253 1.82 Down NM_174854 complete cds; alternatively spliced Olfactory receptor 1441, mRNA (cDNA clone -1.566545 -0.704215 1.82 Up NM_146683 MGC:175734 IMAGE:40131150) Aquaporin 4, mRNA (cDNA clone MGC:37514 0.170415 -0.692765 1.82 Down NM_009700 IMAGE:4985265) chr9:58197113- 0.305825 1.1703 1.82 Up 58200614_F chr9:58197113-58200614_F chr9:96635508- 0.935955 1.80352 1.82 Up 96654148_R chr9:96635508-96654148_R 1.15273 2.01521 1.82 Up BG084090 Transcribed locus Zinc finger protein 820, mRNA (cDNA clone 0.75652 -0.106555 1.82 Down NM_029281 MGC:29393 IMAGE:5066012) RIKEN cDNA C730027P07 gene, mRNA (cDNA 2.63444 3.49858 1.82 Up NM_177743 clone MGC:130602 IMAGE:40058404) Bone morphogenic protein receptor, type II 3.35633 2.492155 1.82 Down NM_007561 (serine/threonine kinase) (Bmpr2), mRNA PR domain containing 1, with ZNF domain (Prdm1), 3.75328 4.615645 1.82 Up NM_007548 mRNA 3.312695 2.451965 1.82 Down NM_001160711 Cd300lg Neuromedin B, mRNA (cDNA clone MGC:41013 7.04189 7.909285 1.82 Up NAP111842-1 IMAGE:1366735) chrX:91000651- 5.25634 4.395445 1.82 Down 91005855_R chrX:91000651-91005855_R 3.13259 2.272185 1.82 Down NM_029741 Liprin-alpha 3 (ppfia3) Heterogeneous nuclear ribonucleoprotein H2, 5.85574 4.988385 1.82 Down NM_019868 mRNA (cDNA clone MGC:6365 IMAGE:3496629) 4.86244 4.001305 1.82 Down NM_001081107 DNA helicase HEL308 (Hel308) chr1:139806645- -1.792515 -0.936595 1.81 Up 139809498_F chr1:139806645-139809498_F chr9:75316023- -0.58193 -1.43724 1.81 Down 75344401_F chr9:75316023-75344401_F chr13:112207480 -1.323565 -2.18003 1.81 Down -112213280_R chr13:112207480-112213280_R chr10:94133769- -1.614775 -2.472 1.81 Down 94151321_R chr10:94133769-94151321_R Laminin, beta 2, mRNA (cDNA clone MGC:13735 -1.821645 -0.96428 1.81 Up NM_008483 IMAGE:4036357) chr3:34497447- -1.865975 -1.01369 1.81 Up 34501170_R chr3:34497447-34501170_R -1.74644 -0.894205 1.81 Up NM_027298 Ccdc89 -1.75846 -0.899475 1.81 Up chr12:109993800 chr12:109993800-109994116_R -109994116_R -1.280805 -2.135985 1.81 Down NM_080451 Synpo2 -2.02619 -1.17067 1.81 Up NM_029974 DC-STAMP domain containing 1 (Dcst1), mRNA chr14:76912477- -1.487915 -0.63036 1.81 Up 76931702_F chr14:76912477-76931702_F chr11:102878974 -0.404515 -1.256615 1.81 Down -102888924_F chr11:102878974-102888924_F PREDICTED: Mus musculus hypothetical gene -0.83796 -1.69192 1.81 Down A_55_P2091816 supported by AK052160 (LOC432868), mRNA Zinc finger protein 459, mRNA (cDNA clone -0.285955 -1.140415 1.81 Down NM_177811 IMAGE:30108895) Ribonucleotide reductase M2 B (TP53 inducible) -0.21381 -1.0722 1.81 Down NM_199476 (Rrm2b), mRNA Histocompatibility 2, M region locus 1 (H2-M1), -1.38882 -0.53469 1.81 Up NM_177636 mRNA chr17:33372482- 0.471625 1.32891 1.81 Up 33375285_R chr17:33372482-33375285_R 0.94643 1.803915 1.81 Up NM_001177364 Heatr7b1 1.472635 2.32493 1.81 Up XR_106478 B830012L14Rik chr9:96635508- 1.298675 2.155295 1.81 Up 96654148_R chr9:96635508-96654148_R Gamma-aminobutyric acid (GABA-A) receptor, 0.76288 1.6211 1.81 Up NM_008072 subunit delta (Gabrd), mRNA BCL2-associated X protein, mRNA (cDNA clone 5.74114 6.596085 1.81 Up NM_007527 MGC:11739 IMAGE:3968903) chr5:15146475- 1.75296 2.6069 1.81 Up 15170100_F chr5:15146475-15170100_F 1.942495 1.08744 1.81 Down NM_001033536 Regulatory factor X, 7 (Rfx7), mRNA MACRO domain containing 2, mRNA (cDNA clone 2.13439 1.275375 1.81 Down NM_028387 IMAGE:1429747) 3.06048 2.200525 1.81 Down NM_023503 Inhibitor of growth family, member 2 (Ing2), mRNA DNA segment, Chr 14, ERATO Doi 436, expressed, 4.79344 5.650585 1.81 Up NM_172599 mRNA (cDNA clone IMAGE:4950756) chr16:84702353- 5.56789 4.713535 1.81 Down 84710928_R chr16:84702353-84710928_R 7.17379 8.029235 1.81 Up NR_003280 LOC790956 ENSMUST00000 4.66609 5.518885 1.81 Up 124012 Sgms1 Casitas B-lineage lymphoma b, mRNA (cDNA clone 5.31454 4.457745 1.81 Down NM_001033238 MGC:183849 IMAGE:9087849) 6.31729 7.174685 1.81 Up NM_024253 Natural killer cell group 7 sequence (Nkg7), mRNA -1.15011 -1.998765 1.8 Down C78660 Transcribed locus -1.667975 -2.51255 1.8 Down NAP115224-1 NAP115224-1 -1.434895 -2.28671 1.8 Down TC1674694 TC1674694 PREDICTED: Mus musculus hypothetical protein -2.21363 -1.361825 1.8 Up NM_183180 LOC100042789 (LOC100042789), mRNA -1.210965 -0.361545 1.8 Up NM_010593 Plakoglobin PREDICTED: Mus musculus hypothetical protein -0.75883 -1.607555 1.8 Down A_55_P2021495 LOC100042679 (LOC100042679), mRNA -1.54078 -0.69481 1.8 Up NM_020504 Claudin 13 (Cldn13) chr11:55315017- -1.242235 -2.08794 1.8 Down 55322092_R chr11:55315017-55322092_R chrX:92119889- -0.80612 -1.656925 1.8 Down 92128492_R chrX:92119889-92128492_R Family with sequence similarity 65, member B -1.07336 -1.91967 1.8 Down NAP067587-1 (Fam65b), transcript variant 2, mRNA chr9:121206619- -1.192445 -2.043545 1.8 Down 121273344_F chr9:121206619-121273344_F -0.18888 0.655665 1.8 Up TC1660977 TC1660977 chr2:48807211- -1.163045 -2.01153 1.8 Down 48843911_F chr2:48807211-48843911_F -2.24374 -1.39784 1.8 Up AK085976 Transcribed locus ENSMUST00000 ARD1 homolog B (S. cerevisiae), mRNA (cDNA -0.65477 -1.50514 1.8 Down 051454 clone MGC:170731 IMAGE:8862126) chr16:94775095- -1.086765 -1.931215 1.8 Down 94775634_F chr16:94775095-94775634_F -1.084205 -1.929875 1.8 Down A_55_P2004624 A_55_P2004624 ENSMUST00000 -0.355815 0.49048 1.8 Up 021520 Epsilon-tubulin 1 (Tube1), mRNA 0.89247 1.738705 1.8 Up NM_033325 Lysyl oxidase-like protein 2 RIKEN cDNA 4933428G20 gene (4933428G20Rik), 1.808115 2.652395 1.8 Up NM_021493 mRNA Family with sequence similarity 49, member A 1.320045 0.469195 1.8 Down NM_029758 (Fam49a), transcript variant 2, mRNA ENSMUST00000 2.52115 1.67147 1.8 Down 096862 ENSMUST00000096862 1.77086 2.616155 1.8 Up NM_029964 6030468B19Rik Mitogen-activated protein kinase 12, mRNA (cDNA 2.307545 3.156185 1.8 Up NM_013871 clone MGC:13901 IMAGE:3979667) G protein-coupled receptor 162, mRNA (cDNA 3.46954 2.62225 1.8 Down NM_013533 clone MGC:25271 IMAGE:4527410) 6.54944 5.697735 1.8 Down NM_001104617 Radixin, mRNA (cDNA clone IMAGE:3484334) Calcineurin binding protein 1, mRNA (cDNA clone 6.19799 5.350035 1.8 Down NM_172549 MGC:183736 IMAGE:9087736) ENSMUST00000 RAB22A, member RAS oncogene family (Rab22a), 6.70549 5.858585 1.8 Down 081163 mRNA Myosin binding protein C, fast-type, mRNA (cDNA 11.83609 10.990585 1.8 Down A_55_P2013680 clone IMAGE:1195676) Sorting nexin 10 (Snx10), transcript variant 1, 4.04002 3.192545 1.8 Down NM_028035 mRNA Roadblock domain containing 3, mRNA (cDNA 4.66409 5.509085 1.8 Up NM_031248 clone MGC:19316 IMAGE:4189054) PREDICTED: Mus musculus hypothetical protein -1.2548 -0.41626 1.79 Up AK090034 LOC100041143 (LOC100041143), mRNA -0.61133 0.229775 1.79 Up NM_207694 Olfr220 chr2:174088550- -0.70353 -1.544715 1.79 Down 174109425_R chr2:174088550-174109425_R -1.18791 -2.024105 1.79 Down NM_001159376 Dusp15 RIKEN cDNA 4930538K18 gene (4930538K18Rik), -2.20574 -1.36956 1.79 Up NM_029198 mRNA PREDICTED: Mus musculus hypothetical protein -1.577185 -2.41984 1.79 Down BC126859 LOC100038850 (LOC100038850), mRNA chr13:51249947- -2.09343 -1.25446 1.79 Up 51250937_F chr13:51249947-51250937_F chr5:112205091- -1.742865 -2.578845 1.79 Down 112240992_F chr5:112205091-112240992_F -1.260935 -2.10143 1.79 Down AK149800 AK149800 Ribosomal protein S6 kinase, polypeptide 2, mRNA -2.12745 -1.284375 1.79 Up NM_011299 (cDNA clone IMAGE:4505898) ENSMUST00000 -1.757865 -2.595845 1.79 Down 097660 Dsg4 mRNA for desmoglein4 chr7:68849401- -1.36876 -0.52794 1.79 Up 68958266_R chr7:68849401-68958266_R -1.781345 -0.938975 1.79 Up NM_080855 M-BDG29 Solute carrier family 6 (neurotransmitter transporter, -1.73253 -2.5718 1.79 Down NM_201353 L-proline), member 7 (Slc6a7), mRNA Transmembrane emp24 protein transport domain -0.27733 -1.121005 1.79 Down AK078317 containing 5 (Tmed5), mRNA -1.50659 -0.66966 1.79 Up NAP101223-1 CDNA clone IMAGE:40039816 -1.69641 -0.856765 1.79 Up XM_001478297 LOC100047504 Thrombospondin, type I, domain containing 7B, mRNA (cDNA clone MGC:66597 -1.793945 -0.953325 1.79 Up AK051714 IMAGE:6410178) KH domain containing, RNA binding, signal -0.43271 0.40458 1.79 Up NM_133235 transduction associated 2 (Khdrbs2), mRNA chr6:12062275- -2.378325 -1.534805 1.79 Up 12075800_F chr6:12062275-12075800_F -0.25472 -1.09566 1.79 Down NM_177695 Transmembrane channel-like protein 3 (Tmc3) chr12:111287772 -0.982575 -0.14392 1.79 Up -111333890_F chr12:111287772-111333890_F chr17:56790296- 0.867755 1.70813 1.79 Up 56803875_F chr17:56790296-56803875_F Heterogeneous nuclear ribonucleoprotein H3 0.65754 1.49808 1.79 Up A_55_P2059283 (Hnrnph3), mRNA 0.5322 -0.311085 1.79 Down NM_001013749 Transmembrane protein 151B (Tmem151b), mRNA ENSMUST00000 0.98145 0.144825 1.79 Down 106026 ENSMUST00000106026 Zinc finger and BTB domain containing 26, mRNA 1.76363 0.92315 1.79 Down NM_199025 (cDNA clone MGC:130360 IMAGE:40056733) 4.72829 3.889445 1.79 Down NM_021604 Agrin, mRNA (cDNA clone IMAGE:5006620) Triggering receptor expressed on myeloid cells 1 5.49189 4.65495 1.79 Down NM_021406 (Trem1), mRNA 1.48146 0.64428 1.79 Down NM_146009 Centrosomal protein 290 (Cep290), mRNA 5.71164 4.87174 1.79 Down NM_016683 Zinc finger protein 95 (Zfp95) High mobility group 20A, mRNA (cDNA clone 6.30304 5.463035 1.79 Down NM_025812 MGC:12002 IMAGE:3602239) TWIST neighbor, mRNA (cDNA clone 5.73569 4.893095 1.79 Down NM_172253 MGC:170789 IMAGE:8862184) chrX:146827709- 1.47794 0.641675 1.79 Down 146913398_F chrX:146827709-146913398_F RIKEN cDNA 6030429G01 gene, mRNA (cDNA 4.85739 4.014735 1.79 Down NM_001033548 clone MGC:183896 IMAGE:9087896) -0.988025 -1.81928 1.78 Down AK078618 7330403C04Rik -1.76393 -2.59932 1.78 Down NM_146787 Olfactory receptor 920 (Olfr920), mRNA chr14:73729977- -1.85298 -1.01807 1.78 Up 73751877_F chr14:73729977-73751877_F -1.770105 -2.60126 1.78 Down XR_107098 Gm10556 chr15:96984422- -1.336695 -2.16604 1.78 Down 97000322_R chr15:96984422-97000322_R -1.82229 -0.98867 1.78 Up NM_007556 Bone morphogenetic protein 6 (Bmp6), mRNA -1.386505 -2.214415 1.78 Down CF532098 Transcribed locus -1.27819 -2.10731 1.78 Down NM_001163787 Ccdc151 chr8:67550064- -1.118855 -0.284215 1.78 Up 67560987_R chr8:67550064-67560987_R chr4:33369310- -1.741275 -2.575635 1.78 Down 33369871_R chr4:33369310-33369871_R chr6:28164118- -2.05401 -1.219005 1.78 Up 28165468_F chr6:28164118-28165468_F -2.24051 -1.40467 1.78 Up NM_198630 1810024B03Rik -1.09369 -0.261535 1.78 Up CA752298 Transcribed locus -2.02057 -1.1914 1.78 Up AK157412 Gm10370 -1.39751 -0.569165 1.78 Up NAP100227-001 CDNA sequence BC085271 (BC085271), mRNA -0.27949 -1.113375 1.78 Down AK047640 Ptpru -2.25192 -1.42134 1.78 Up NM_001164524 Serpinb9c -0.88949 -0.05644 1.78 Up NM_181818 Olfactory receptor 141 (Olfr141), mRNA 3.15251 2.32037 1.78 Down NM_001168294 Serpina3f 0.155005 -0.67336 1.78 Down AK050412 Transcribed locus 1.200045 2.0348 1.78 Up NM_146162 Transmembrane protein 119 (Tmem119), mRNA Heat shock protein 1, mRNA (cDNA clone 0.83175 1.66119 1.78 Up NM_013560 MGC:6141 IMAGE:3498180) 3.78958 2.96175 1.78 Down AK076764 AK076764 Family with sequence similarity 164, member A, mRNA (cDNA clone MGC:90536 1.49842 0.667665 1.78 Down NM_173181 IMAGE:6850296) RIKEN cDNA C130038G02 gene 3.904615 3.07508 1.78 Down NM_029920 (C130038G02Rik), transcript variant 2, mRNA Elastase 1, pancreatic, mRNA (cDNA clone 3.33067 4.16051 1.78 Up NM_033612 MGC:19111 IMAGE:4208442) 1.74867 2.5776 1.78 Up NM_010388 Histocompatibility 2, class II, locus Mb2 (H2- DMb2), mRNA 3.86252 3.033375 1.78 Down NM_138949 Zinc finger protein 286 (Zfp286), mRNA 5.23929 6.069885 1.78 Up AK049648 Transcribed locus 1.598945 2.43262 1.78 Up AK083360 Transcribed locus 4.25169 3.422725 1.78 Down NM_001146275 Iigp1 Family with sequence similarity 131, member B 1.19348 0.358075 1.78 Down NM_029528 (Fam131b), transcript variant a, mRNA Protein kinase C and casein kinase substrate in neurons 1, mRNA (cDNA clone MGC:25285 1.826315 0.997695 1.78 Down NM_011861 IMAGE:4527708) chr17:24152225- 2.47124 1.637635 1.78 Down 24169870_R chr17:24152225-24169870_R chr16:84702353- 5.32779 4.49563 1.78 Down 84710928_R chr16:84702353-84710928_R ENSMUST00000 2.84678 3.681185 1.78 Up 139760 Itga6 Solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3, mRNA 1.935825 1.104195 1.78 Down NM_054055 (cDNA clone MGC:28679 IMAGE:4238769) Chloride channel Kb, mRNA (cDNA clone 1.61916 2.451885 1.78 Up NM_019701 MGC:28502 IMAGE:4188062) MAX dimerization protein 1, mRNA (cDNA clone 7.01699 6.186285 1.78 Down NM_010751 IMAGE:5345831) chr7:134603123- -1.690795 -2.51416 1.77 Down 134614510_F chr7:134603123-134614510_F PR domain containing 2, with ZNF domain, mRNA -1.619825 -2.44467 1.77 Down NM_001081355 (cDNA clone MGC:183975 IMAGE:9087975) -0.44864 -1.27324 1.77 Down NM_007537 BCL2-like 2 (Bcl2l2), mRNA -1.80489 -0.984795 1.77 Up NM_010932 Prepronociceptin chr4:62367014- -1.77265 -2.599375 1.77 Down 62386800_F chr4:62367014-62386800_F chr4:155585650- -1.13076 -1.957195 1.77 Down 155608700_F chr4:155585650-155608700_F chr11:16831925- -0.270075 -1.090655 1.77 Down 16851121_F chr11:16831925-16851121_F chr8:67542714- -2.14429 -1.32182 1.77 Up 67561694_F chr8:67542714-67561694_F Solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 (Slc24a2), transcript variant -1.39144 -0.56663 1.77 Up NM_172426 2, mRNA chr6:13801450- -1.46205 -2.28212 1.77 Down 13853450_F chr6:13801450-13853450_F -1.403845 -0.577885 1.77 Up AF401983 Imprinted zinc-finger 2 gene, partial sequence -0.679425 -1.507085 1.77 Down C79246 Transcribed locus -1.09435 -0.27416 1.77 Up NM_008779 Contactin 3 (Cntn3), mRNA chr17:17143325- -1.757525 -0.93305 1.77 Up 17181500_R chr17:17143325-17181500_R -1.59999 -0.77258 1.77 Up chr10:24269165- chr10:24269165-24276690_F 24276690_F -0.6875 0.132395 1.77 Up NM_146981 Olfactory receptor 1260 (Olfr1260), mRNA ENSMUST00000 V-myc myelocytomatosis viral oncogene homolog 1, -1.495545 -0.67022 1.77 Up 034653 lung carcinoma derived (avian) (Mycl1), mRNA -0.207715 -1.029715 1.77 Down NM_001081277 AK5 mRNA for adenylate kinase isozyme 5 0.414355 1.24103 1.77 Up NM_011880 Regulator of G protein signaling 7 (Rgs7), mRNA Leucine rich repeat containing 27 (Lrrc27), transcript 0.348095 1.17152 1.77 Up NM_027164 variant 2, mRNA chr14:14660983- 0.45476 1.275945 1.77 Up 14746992_R chr14:14660983-14746992_R 1.32514 0.49812 1.77 Down NM_009841 CD14 antigen (Cd14), mRNA Interferon induced transmembrane protein 6 (Ifitm6), 1.90914 1.085005 1.77 Down NM_001033632 mRNA chr17:27479404- 1.957 2.779195 1.77 Up 27481770_F chr17:27479404-27481770_F 1.432515 2.255935 1.77 Up NM_001159486 Mcf2l Microtubule-associated protein 1 light chain 3 alpha 3.572375 4.392585 1.77 Up NM_025735 (Map1lc3a), mRNA PREDICTED: Mus musculus predicted gene, 3.767945 2.94334 1.77 Down AK032716 EG544848, transcript variant 1 (EG544848), mRNA 2.668515 3.48959 1.77 Up NM_198664 TBC1 domain family, member 2 (Tbc1d2), mRNA RIKEN cDNA 2610019F03 gene, mRNA (cDNA 2.049895 1.225295 1.77 Down NM_173744 clone MGC:178848 IMAGE:9053840) AP1 gamma subunit binding protein 1 (Ap1gbp1), 5.57979 4.756035 1.77 Down NM_194341 transcript variant 1, mRNA 5.25509 4.43203 1.77 Down NM_001146275 Iigp1 Kinesin family member 5A (Kif5a), transcript 2.852855 2.02526 1.77 Down NM_001039000 variant 1, mRNA 7.71004 6.884335 1.77 Down NR_033535 Gm10845 Kinesin family member 1A (Kif1a), transcript 3.384375 2.56359 1.77 Down NM_008440 variant 1, mRNA 4.39274 3.569345 1.77 Down NM_198620 RUN domain containing 3B (Rundc3b), mRNA Eukaryotic translation initiation factor 3, subunit J 5.95709 5.136585 1.77 Down NM_144545 (Eif3j), mRNA chr12:16833551- 5.82284 4.998915 1.77 Down 16901804_F chr12:16833551-16901804_F Interferon-stimulated protein, mRNA (cDNA clone 5.29459 6.120235 1.77 Up NM_020583 MGC:31697 IMAGE:4912320) Interferon, alpha-inducible protein 27 like 1, mRNA 8.85189 8.031835 1.77 Down NM_026790 (cDNA clone MGC:149996 IMAGE:40091489) Adrenergic receptor kinase, beta 2 (Adrbk2), -1.72404 -0.90979 1.76 Up NM_001035531 transcript variant 2, mRNA PREDICTED: Mus musculus predicted gene, -0.891715 -1.705365 1.76 Down CO815368 EG629966 (EG629966), mRNA ArfGAP with RhoGAP domain, ankyrin repeat and ENSMUST00000 PH domain 2, mRNA (cDNA clone -0.32143 -1.13463 1.76 Down 035244 IMAGE:3710592) chr6:126502067- -1.47897 -2.297865 1.76 Down 126507755_R chr6:126502067-126507755_R GRINL1A complex locus, mRNA (cDNA clone -1.12556 -1.93861 1.76 Down NM_001033208 MGC:170705 IMAGE:8862100) chr9:78367773- -1.40601 -2.224525 1.76 Down 78374723_F chr9:78367773-78374723_F chr7:133402766- -1.402345 -0.5877 1.76 Up 133415516_R chr7:133402766-133415516_R ENSMUST00000 Vesicle-associated membrane protein 1 (Vamp1), -0.960105 -1.773775 1.76 Down 148627 transcript variant 1, mRNA -1.082735 -0.26843 1.76 Up NM_010401 Histidine ammonia lyase (Hal), mRNA Calcitonin/calcitonin-related polypeptide, alpha, ENSMUST00000 mRNA (cDNA clone MGC:41274 -0.71352 0.10311 1.76 Up 142544 IMAGE:1399214) -0.504235 -1.31627 1.76 Down NM_001159953 Pde1c chr2:170029045- -0.718285 -1.531085 1.76 Down 170034220_F chr2:170029045-170034220_F ENSMUST00000 Transforming, acidic coiled-coil containing protein -0.824235 -1.64387 1.76 Down 110332 1, mRNA (cDNA clone IMAGE:40131012) Zinc finger and SCAN domain containing 4C -0.110795 -0.925025 1.76 Down NM_001013765 (Zscan4c), mRNA chr5:99726262- -1.02678 -0.209965 1.76 Up 100264512_R chr5:99726262-100264512_R -1.534095 -0.721155 1.76 Up AK043596 Transcribed locus chr5:113609906- -0.530595 -1.346035 1.76 Down 113622032_R chr5:113609906-113622032_R chr16:59557120- -0.145735 -0.957445 1.76 Down 59602070_R chr16:59557120-59602070_R chr19:46422690- -0.496055 0.31808 1.76 Up 46423478_R chr19:46422690-46423478_R chrX:75813213- -0.400895 -1.217095 1.76 Down 75829323_R chrX:75813213-75829323_R chr17:7002731- 0.387435 -0.4272 1.76 Down 7032535_R chr17:7002731-7032535_R Predicted gene, OTTMUSG00000004968 1.20628 2.01945 1.76 Up NM_001127354 (OTTMUSG00000004968), mRNA chr8:34646787- 2.53447 1.719995 1.76 Down 34680312_F chr8:34646787-34680312_F Hepatocyte growth factor activator, mRNA (cDNA 1.2904 2.102075 1.76 Up NM_019447 clone MGC:30305 IMAGE:5134851) Ring finger protein, transmembrane 2 (Rnft2), 1.524955 0.706765 1.76 Down NM_172998 transcript variant 2, mRNA Protein-L-isoaspartate (D-aspartate) O- ENSMUST00000 methyltransferase domain containing 1, mRNA 0.72162 -0.09172 1.76 Down 131108 (cDNA clone MGC:144113 IMAGE:40097836) chr15:8463685- 1.740145 0.92773 1.76 Down 8494960_R chr15:8463685-8494960_R PiggyBac transposable element derived 5, mRNA 2.343365 1.5285 1.76 Down A_55_P2143516 (cDNA clone MGC:106643 IMAGE:30606749) 2.85558 3.66879 1.76 Up NM_001168500 A330049M08Rik Mannosidase, beta A, lysosomal, mRNA (cDNA 5.24059 4.42908 1.76 Down NM_027288 clone MGC:35624 IMAGE:4952710) chr5:92548501- 1.67363 2.490785 1.76 Up 92566401_F chr5:92548501-92566401_F 7.25304 6.433735 1.76 Down NM_021537 Serine/threonine kinase 25 (yeast) (Stk25), mRNA 1.89601 1.07972 1.76 Down NM_001029868 PDZ domain containing 4 (Pdzd4), mRNA 6.77714 5.959685 1.76 Down NM_009331 Transcription factor 7, T-cell specific (Tcf7), mRNA T-cell lymphoma invasion and metastasis 1 (Tiam1), 5.42194 4.60592 1.76 Down NM_009384 transcript variant 1, mRNA Kinesin family member 5A (Kif5a), transcript -0.228405 -1.03353 1.75 Down NM_008447 variant 1, mRNA chr9:88333945- -1.49011 -2.295615 1.75 Down 88342370_F chr9:88333945-88342370_F chr13:23517278- -1.514885 -2.323115 1.75 Down 23523756_F chr13:23517278-23523756_F CD160 antigen, mRNA (cDNA clone MGC:35946 -1.566775 -0.762885 1.75 Up NM_018767 IMAGE:5098004) Complement component 6, mRNA (cDNA clone -0.74823 -1.55251 1.75 Down NM_016704 MGC:18813 IMAGE:4196330) -1.8169 -1.008795 1.75 Up NM_023755 Transcription factor CP2-like 1 (Tcfcp2l1), mRNA chr3:85806420- -1.141695 -0.33636 1.75 Up 85889300_R chr3:85806420-85889300_R -1.177095 -1.983645 1.75 Down NM_134114 SFT2 domain containing 1 (Sft2d1), mRNA Tubby candidate gene, mRNA (cDNA clone -1.744275 -0.939345 1.75 Up NM_021885 IMAGE:4527484) -0.260295 -1.06887 1.75 Down NM_198300 CDNA clone IMAGE:40111838 ENSMUST00000 -1.19481 -0.3871 1.75 Up 155069 Vomeronasal 2, receptor 91 (Vmn2r91), mRNA ENSMUST00000 -0.292375 -1.102905 1.75 Down 096411 EFR3 homolog A (S. cerevisiae) (Efr3a), mRNA chr14:28231577- -0.558355 0.25058 1.75 Up 28242027_F chr14:28231577-28242027_F Zinc finger protein 536, mRNA (cDNA clone 0.482465 -0.32103 1.75 Down NM_172385 MGC:40803 IMAGE:5367892) RAR-related orphan receptor beta (Rorb), transcript 0.923325 1.727345 1.75 Up NM_001043354 variant 2, mRNA 1.10291 1.90736 1.75 Up NM_029069 Fam71d ENSMUST00000 1.054715 0.24847 1.75 Down 162453 Strain ILS microtubule binding protein tau 2.12672 2.932245 1.75 Up NM_146001 Huntingtin interacting protein 1 (Hip1), mRNA Cell adhesion molecule 2 (Cadm2), transcript variant 0.69767 -0.106375 1.75 Down A_55_P2142937 2, mRNA 1.629605 0.824415 1.75 Down NM_001001152 Zinc finger protein 458 (Zfp458), mRNA chr16:84702353- 4.71099 3.90389 1.75 Down 84710928_F chr16:84702353-84710928_F ArfGAP with RhoGAP domain, ankyrin repeat and 4.78674 3.976445 1.75 Down NM_178407 PH domain 2, mRNA (cDNA clone IMAGE:3710592) 2.547405 1.74139 1.75 Down NM_019930 RAN binding protein 9 (Ranbp9), mRNA Riboflavin kinase, mRNA (cDNA clone 4.84714 4.042665 1.75 Down NM_019437 MGC:35594 IMAGE:4527980) Interferon-stimulated protein, mRNA (cDNA clone 3.882185 4.690085 1.75 Up NM_020583 MGC:31697 IMAGE:4912320) 7.00804 6.197635 1.75 Down NM_013524 Fucosyltransferase 7 (Fut7), mRNA 5.04299 4.23715 1.75 Down NM_013730 Type I membrane receptor SLAM1 (Slam) 6.16669 6.977235 1.75 Up A_55_P2175451 A_55_P2175451 PRP19/PSO4 pre-mRNA processing factor 19 4.55794 3.74825 1.75 Down NM_134129 homolog (S. cerevisiae) (Prpf19), mRNA -1.524375 -2.32493 1.74 Down PINC PINC LanC lantibiotic synthetase component C-like 3 -1.403775 -2.203465 1.74 Down NM_173414 (bacterial), mRNA (cDNA clone IMAGE:40060880) ENSMUST00000 -1.057605 -1.85721 1.74 Down 114068 MADP-1 protein -0.82871 -1.62577 1.74 Down NM_018781 Early growth response 3 (Egr3), mRNA ENSMUST00000 -1.14519 -1.942915 1.74 Down 138492 ENSMUST00000138492 CDC42 effector protein (Rho GTPase binding) 1 -0.62298 -1.418245 1.74 Down NM_027219 (Cdc42ep1), mRNA chr6:128389484- -1.35556 -2.150975 1.74 Down 128403407_R chr6:128389484-128403407_R MAS-related GPR, member B5, mRNA (cDNA -1.17069 -1.972685 1.74 Down NM_207538 clone MGC:163634 IMAGE:40130280) PREDICTED: Mus musculus hypothetical protein -1.277285 -2.07952 1.74 Down BE652559 LOC100043727 (LOC100043727), mRNA -1.50255 -2.30094 1.74 Down NM_001166729 Vmn1r31 -1.3341 -2.135965 1.74 Down NM_027438 Paraneoplastic antigen MA1 (Pnma1), mRNA -1.13368 -1.929655 1.74 Down NM_008626 Mannose receptor, C type 2 (Mrc2), mRNA chr2:155269145- -0.471325 -1.270325 1.74 Down 155303251_F chr2:155269145-155303251_F -0.156775 -0.957415 1.74 Down NM_009620 ADAM 4 protein precursor (ADAM 4) -1.175965 -1.973025 1.74 Down NM_153093 CDNA sequence AF366264 (AF366264), mRNA -1.41003 -2.207255 1.74 Down AK139156 BetaPix-d chr15:85421725- -1.054615 -1.857125 1.74 Down 85424047_F chr15:85421725-85424047_F -0.83019 -1.630465 1.74 Down NM_010426 Forkhead box F1a (Foxf1a), mRNA Solute carrier family 45, member 1 (Slc45a1), -1.36972 -2.165405 1.74 Down NM_173774 mRNA Claudin 5, mRNA (cDNA clone MGC:5820 -1.40597 -0.607485 1.74 Up NM_013805 IMAGE:3488769) chr12:20240893- -1.2949 -0.497435 1.74 Up 20435318_R chr12:20240893-20435318_R Solute carrier family 7 (cationic amino acid -0.183285 0.616435 1.74 Up NM_016972 transporter, y+ system), member 8 (Slc7a8), mRNA -0.94592 -0.14675 1.74 Up ENSMUST00000 Guanine nucleotide binding protein, alpha z subunit, 143403 mRNA (cDNA clone MGC:25486 IMAGE:4501587) chr3:41327493- -0.820735 -1.617505 1.74 Down 41328368_F chr3:41327493-41328368_F chr14:64735748- -0.69257 0.10725 1.74 Up 64736349_R chr14:64735748-64736349_R 0.266195 1.06656 1.74 Up NM_021424 Poliovirus receptor-related 1 (Pvrl1), mRNA Cyclin-dependent kinase-like 2 (CDC2-related 0.894585 0.093345 1.74 Down NM_016912 kinase) (Cdkl2), transcript variant 1, mRNA Heme oxygenase (decycling) 1, mRNA (cDNA 0.8065 1.606775 1.74 Up NM_010442 clone MGC:18463 IMAGE:4235374) CDNA sequence BC039771, mRNA (cDNA clone 2.542495 1.7434 1.74 Down NM_028724 IMAGE:4166439) Aquaporin 11, mRNA (cDNA clone 1.840465 2.641775 1.74 Up NM_175105 IMAGE:5126527) ENSMUST00000 1.30169 2.09667 1.74 Up 156405 Mcf2l chr16:84702353- 3.56455 2.76507 1.74 Down 84710928_F chr16:84702353-84710928_F AHNAK nucleoprotein (desmoyokin), mRNA 3.53631 2.739175 1.74 Down NM_001039959 (cDNA clone IMAGE:4977508) Family with sequence similarity 65, member B 2.24635 1.45119 1.74 Down NM_001080381 (Fam65b), transcript variant 2, mRNA Sorting nexin 10 (Snx10), transcript variant 1, 2.55111 1.75074 1.74 Down NM_028035 mRNA Ectonucleotide pyrophosphatase/phosphodiesterase 2, mRNA (cDNA clone MGC:6665 9.11334 8.310435 1.74 Down NM_001136077 IMAGE:3499038) 0.71632 1.518255 1.74 Up NM_011923 Angiopoietin-related protein-2 mRNA,complete cds Ubiquitin specific peptidase 21, mRNA (cDNA 2.143605 1.3426 1.74 Down NAP069232-1 clone MGC:18739 IMAGE:3985792) Component of oligomeric golgi complex 1 (Cog1), 6.86804 6.071585 1.74 Down A_55_P2125868 mRNA 3.229375 2.429125 1.74 Down NM_027547 PR domain containing 5 (Prdm5), mRNA chr16:43635730- 4.79774 4.000115 1.74 Down 43639104_F chr16:43635730-43639104_F 9.05749 8.258885 1.74 Down NM_010735 Lymphotoxin A (Lta), mRNA HIRA interacting protein 3, mRNA (cDNA clone 7.41984 6.623185 1.74 Down NM_172746 MGC:66546 IMAGE:6414655) PREDICTED: Mus musculus similar to Sm D2, 9.37079 8.567935 1.74 Down NM_026943 transcript variant 2 (LOC100043618), mRNA Aurora kinase B, mRNA (cDNA clone MGC:5803 -1.103005 -1.89554 1.73 Down NM_011496 IMAGE:3501444) -0.357105 -1.149705 1.73 Down A_55_P2063553 A_55_P2063553 -1.77924 -2.573305 1.73 Down NM_028493 MKIAA0878 protein Zinc finger, CCHC domain containing 12 (Zcchc12), -1.729475 -0.935645 1.73 Up NM_028325 mRNA chr3:60288326- -1.49616 -2.283205 1.73 Down 60288925_R chr3:60288326-60288925_R chr2:108456668- -1.763225 -2.556465 1.73 Down 108532418_F chr2:108456668-108532418_F Hedgehog interacting protein-like 1 (Hhipl1), -1.901885 -1.109455 1.73 Up A_55_P2137045 mRNA chr10:93819821- -1.22776 -2.01734 1.73 Down 93976621_R chr10:93819821-93976621_R chr17:5795893- -1.076 -1.86513 1.73 Down 5835243_F chr17:5795893-5835243_F chr13:12792150- -0.2521 0.537365 1.73 Up 12869825_F chr13:12792150-12869825_F POU domain, class 1, transcription factor 1 (Pit1, -1.9974 -1.208865 1.73 Up NM_008849 growth hormone factor 1) (Pou1f1), mRNA chr2:143992000- -2.274195 -1.479545 1.73 Up 143992611_F chr2:143992000-143992611_F SEC14-like 4 (S. cerevisiae), mRNA (cDNA clone -2.16712 -1.379955 1.73 Up NM_146013 IMAGE:5097361) chr14:121850951 -1.022685 -0.23409 1.73 Up -121854978_R chr14:121850951-121854978_R chr11:68200716- -1.128645 -0.342005 1.73 Up 68214458_R chr11:68200716-68214458_R chr1:195332659- -1.15964 -0.3652 1.73 Up 195335997_R chr1:195332659-195335997_R chr2:84344350- -1.11643 -0.321615 1.73 Up 84370075_F chr2:84344350-84370075_F 0.679255 1.467505 1.73 Up NM_001198933 Me1 0.563635 1.35188 1.73 Up NM_207667 FGF-14C (FHF-4C) RIKEN cDNA 1300007F04 gene (1300007F04Rik), 0.48669 -0.30273 1.73 Down NM_026185 mRNA Chemokine (C-C motif) ligand 6, mRNA (cDNA 1.38861 2.177715 1.73 Up NM_009139 clone MGC:6215 IMAGE:3492808) Carboxypeptidase E, mRNA (cDNA clone 2.123775 1.33705 1.73 Down NM_013494 MGC:7101 IMAGE:3157558) 1.22572 2.015165 1.73 Up NM_001170801 Ipcef1 Fatty acid binding protein 4, adipocyte (Fabp4), 4.60577 3.81553 1.73 Down NM_024406 mRNA chr4:128727332- 0.321715 -0.467855 1.73 Down 128735227_F chr4:128727332-128735227_F 1.609435 0.817645 1.73 Down NM_178778 CDNA clone IMAGE:9053535 2.34065 1.550445 1.73 Down NM_016854 Protein phosphatase 1 binding protein PTG 3.28015 2.48702 1.73 Down NR_030677 BC025920 4.27911 3.48885 1.73 Down NM_026176 Phosducin-like (Pdcl), mRNA RIKEN cDNA 2610019F03 gene, mRNA (cDNA 4.63954 3.847905 1.73 Down NM_173744 clone MGC:178848 IMAGE:9053840) Aldhehyde dehydrogenase family 5, subfamily A1, mRNA (cDNA clone MGC:170330 4.58234 3.79362 1.73 Down NM_172532 IMAGE:8861725) MAP kinase-activated protein kinase 2, mRNA 0.853525 0.06683 1.73 Down NAP115343-1 (cDNA clone IMAGE:5003277) Zinc finger protein 239, mRNA (cDNA clone 1.8142 1.021115 1.73 Down NM_001001792 MGC:7007 IMAGE:3155528) chrX:20555593- 2.03249 1.2447 1.73 Down 20591971_F chrX:20555593-20591971_F RIKEN cDNA 5730589K01 gene, mRNA (cDNA 4.08045 3.293445 1.73 Down NM_023434 clone IMAGE:3989816) Dermatan sulfate epimerase-like, mRNA (cDNA 4.071895 3.27914 1.73 Down NM_001081316 clone MGC:169420 IMAGE:8860815) 3.43727 2.646825 1.73 Down NM_029823 Arxes2 5.11194 4.321815 1.73 Down NM_001005358 Zfp960 2.55942 3.346655 1.73 Up NM_001174053 Camk2b -0.40777 -1.18749 1.72 Down NM_028021 Nonmuscle myosin II-C2 (Myh14) -2.144965 -1.36208 1.72 Up NM_146384 Olfactory receptor 208 (Olfr208), mRNA Pirin, mRNA (cDNA clone MGC:37739 -1.826025 -1.042195 1.72 Up NM_027153 IMAGE:5067536) -1.843045 -2.62446 1.72 Down A_55_P2064401 Transcribed locus Adrenergic receptor kinase, beta 2 (Adrbk2), -1.177705 -0.39436 1.72 Up NM_177078 transcript variant 2, mRNA AT rich interactive domain 3C (BRIGHT-like), mRNA (cDNA clone MGC:179136 -1.927 -1.14712 1.72 Up NM_001017362 IMAGE:9054128) Family with sequence similarity 54, member B -0.782145 -1.560485 1.72 Down A_55_P1957123 (Fam54b), mRNA RIKEN cDNA 4930444G20 gene (4930444G20Rik), -1.212755 -1.991385 1.72 Down NM_053264 mRNA DnaJ (Hsp40) homolog, subfamily C, member 28 -1.08942 -1.871265 1.72 Down NM_138664 (Dnajc28), transcript variant 2, mRNA ENSMUST00000 -1.41239 -2.194685 1.72 Down 124575 Transcribed locus chr7:46705675- -1.41346 -2.193225 1.72 Down 46735750_R chr7:46705675-46735750_R Transmembrane 4 L six family member 20 -1.93733 -1.158535 1.72 Up NM_025453 (Tm4sf20), mRNA chr9:56911160- -0.918275 -1.698135 1.72 Down 56911452_F chr9:56911160-56911452_F Transcribed locus, moderately similar to XP_001473690.1 PREDICTED: similar to Sycp3 -1.10608 -0.32534 1.72 Up AK014857 like Y-linked [Mus musculus] -0.890685 -0.1109 1.72 Up NAP095950-001 Predicted gene, EG434179 (EG434179), mRNA chr17:44503516- -0.88984 -0.105505 1.72 Up 44504852_R chr17:44503516-44504852_R -0.645205 -1.427035 1.72 Down TC1638289 TC1638289 -2.10272 -1.31717 1.72 Up NM_029002 NK6 homeobox 3 (Nkx6-3), mRNA chr6:11996975- -0.96049 -1.740105 1.72 Down 12037300_R chr6:11996975-12037300_R -0.766465 -1.54637 1.72 Down AK084616 Transcribed locus Claudin 11, mRNA (cDNA clone MGC:14055 -0.8976 -1.679095 1.72 Down NM_008770 IMAGE:4190031) Olfactory receptor 996, mRNA (cDNA clone -1.479325 -0.69846 1.72 Up NM_146437 MGC:156019 IMAGE:40129705) chr18:61781410- -1.412255 -0.626225 1.72 Up 61788685_R chr18:61781410-61788685_R chrX:146827709- -0.44187 -1.22201 1.72 Down 146913398_R chrX:146827709-146913398_R chr3:131128972- -2.129755 -1.343835 1.72 Up 131163308_F chr3:131128972-131163308_F -0.494515 0.290465 1.72 Up NM_023727 MRNA, partial cds, clone:2-43 -0.62883 -1.411775 1.72 Down XR_105752 Gm5480 RIKEN cDNA 6330408A02 gene, mRNA (cDNA -0.300155 0.48526 1.72 Up NM_177312 clone MGC:100086 IMAGE:30608389) chr8:41941084- -0.401005 -1.18729 1.72 Down 41947630_R chr8:41941084-41947630_R chr12:81217572- -0.45951 -1.23943 1.72 Down 81233910_F chr12:81217572-81233910_F CDNA fis, clone TRACH2016551, highly similar to 0.353705 -0.431065 1.72 Down NM_011794 Mus musculus bisphosphate 3-nucleotidase mRNA chr5:35975265- 0.60358 -0.1802 1.72 Down 35982561_R chr5:35975265-35982561_R 2.422505 1.64003 1.72 Down NM_008366 Strain C3HeB/FeJ interleukin 2 (Il2) 2.408085 3.1884 1.72 Up NM_007720 Chemokine (C-C motif) receptor 8 (Ccr8), mRNA Low density lipoprotein receptor-related protein 11 0.918075 0.133805 1.72 Down NM_172784 (Lrp11), mRNA chr9:96632664- 3.22164 4.0044 1.72 Up 96653249_R chr9:96632664-96653249_R Leucine rich repeat and Ig domain containing 4, mRNA (cDNA clone MGC:143955 2.48197 1.697055 1.72 Down NM_177250 IMAGE:40095468) Solute carrier family 4 (anion exchanger), member 2, 4.5525 3.77086 1.72 Down NM_009207 mRNA (cDNA clone IMAGE:3491550) Solute carrier family 5 (sodium/glucose cotransporter), member 10, mRNA (cDNA clone 1.633425 2.41653 1.72 Up NM_001033227 MGC:176286 IMAGE:9055937) NIMA (never in mitosis gene a)-related expressed ENSMUST00000 kinase 1, mRNA (cDNA clone MGC:198796 1.955225 1.17502 1.72 Down 103641 IMAGE:9054377) 3.830055 3.047615 1.72 Down NM_031374 Testis expressed gene 15 (Tex15), mRNA Intestinal cell kinase, mRNA (cDNA clone 2.28898 1.50693 1.72 Down NM_019987 MGC:28949 IMAGE:4224269) RIKEN cDNA B230219D22 gene, mRNA (cDNA 7.87554 7.093835 1.72 Down NM_181278 clone IMAGE:3711169) 5.52079 4.737325 1.72 Down NM_145836 Polyglutamine-containing protein Sorting nexin 16 (Snx16), transcript variant 1, 2.176245 1.395245 1.72 Down NM_001127191 mRNA RIKEN cDNA 2400003C14 gene, mRNA (cDNA 5.75189 4.9675 1.72 Down NM_028018 clone MGC:6464 IMAGE:2631157) 4.098055 3.31862 1.72 Down NM_010629 Kinesin-associated protein 3 (Kifap3), mRNA Rho GDP dissociation inhibitor (GDI) gamma, 4.386345 3.603745 1.72 Down NM_008113 mRNA (cDNA clone MGC:5923 IMAGE:3490167) 8.10459 7.325935 1.72 Down NM_008228 Histone deacetylase 1 (Hdac1), mRNA Coproporphyrinogen oxidase, mRNA (cDNA clone 7.83309 7.053085 1.72 Down NM_007757 MGC:18469 IMAGE:4241687) chr6:47687025- 5.90429 5.123035 1.72 Down 47728525_F chr6:47687025-47728525_F F-box and leucine-rich repeat protein 15 (Fbxl15), 4.89149 4.10932 1.72 Down NM_133694 mRNA RAR-related orphan receptor gamma, mRNA 6.94794 6.163785 1.72 Down NM_011281 (cDNA clone MGC:25220 IMAGE:4489193) chr5:125190100- -0.767995 -1.539115 1.71 Down 125209625_R chr5:125190100-125209625_R Signal-regulatory protein alpha, mRNA (cDNA -0.73195 -1.5019 1.71 Down NM_007547 clone IMAGE:5035438) Dystrophia myotonica-containing WD repeat motif, ENSMUST00000 mRNA (cDNA clone MGC:37679 -1.43132 -2.20844 1.71 Down 077142 IMAGE:5054380) chr13:67806242- -1.45446 -2.229835 1.71 Down 67830110_R chr13:67806242-67830110_R Insulin-like growth factor 2 (Igf2), transcript variant -0.76765 -1.54557 1.71 Down NM_010514 1, mRNA Microtubule associated serine/threonine kinase 1 -1.18712 -1.963425 1.71 Down NAP052748-1 (Mast1), mRNA ENSMUST00000 Cytochrome c oxidase, subunit XVII assembly -0.55814 -1.335135 1.71 Down 169242 protein homolog (yeast) (Cox17), mRNA Transcribed locus, strongly similar to XP_001480961.1 PREDICTED: hypothetical protein -1.598135 -2.37208 1.71 Down AK137104 [Mus musculus] chr5:100845342- -1.251495 -2.0221 1.71 Down 100869667_F chr5:100845342-100869667_F Eph receptor A7, mRNA (cDNA clone MGC:14056 -2.101615 -1.325035 1.71 Up NM_001122889 IMAGE:3991628) -1.665615 -0.89576 1.71 Up NM_028826 Septin 14 (Sept14), mRNA chr3:35782698- -2.23513 -1.458185 1.71 Up 35789748_F chr3:35782698-35789748_F -1.275115 -0.50002 1.71 Up AU024546 Transcribed locus chr2:158169020- -1.528775 -2.306295 1.71 Down 158191295_F chr2:158169020-158191295_F -0.43607 -1.21119 1.71 Down NR_030678 AA387883 chr13:60508775- -1.08934 -1.863715 1.71 Down 60534625_F chr13:60508775-60534625_F chr10:8662761- -0.672305 -1.44543 1.71 Down 8665101_R chr10:8662761-8665101_R chr19:21653968- -0.998935 -0.223685 1.71 Up 21671718_R chr19:21653968-21671718_R chrX:47893703- -1.83107 -1.05425 1.71 Up 47996700_R chrX:47893703-47996700_R -0.11914 -0.894645 1.71 Down chr8:124355710- chr8:124355710-124401160_F 124401160_F chr17:14320464- -1.02726 -0.25262 1.71 Up 14320975_F chr17:14320464-14320975_F -1.271455 -0.497965 1.71 Up TC1718587 TC1718587 -1.91547 -1.14406 1.71 Up NM_010460 Homeo box B7 (Hoxb7), mRNA chr13:53100475- -1.6485 -0.87186 1.71 Up 53113850_F chr13:53100475-53113850_F Echinoderm microtubule associated protein like 1, 0.752665 1.52716 1.71 Up NM_001043335 mRNA (cDNA clone IMAGE:4456782) Peroxisome proliferative activated receptor, gamma, 0.26073 -0.513365 1.71 Down NM_133249 coactivator 1 beta (Ppargc1b), mRNA 0.27935 -0.495745 1.71 Down NM_001110513 Olf-1/EBF-like-4S transcription factor (O/E-4S) 0.76233 1.534585 1.71 Up NM_153114 Otospiralin (Otos), mRNA Phospholipase C beta 4 [Mus musculus], mRNA 1.49054 0.71523 1.71 Down AK036896 sequence Oxysterol binding protein-like 1A, mRNA (cDNA 1.9037 1.130975 1.71 Down NM_207530 clone IMAGE:4014130) Fc receptor, IgE, high affinity I, gamma polypeptide, mRNA (cDNA clone MGC:36077 2.916975 3.692875 1.71 Up NM_010185 IMAGE:5065647) Beta-gamma crystallin domain containing 3 3.508215 2.73684 1.71 Down NM_174848 (Crybg3), mRNA 3.055875 3.82575 1.71 Up NM_011611 CD40 antigen (Cd40), transcript variant 5, mRNA 4.13966 4.916935 1.71 Up NM_013539 SPRY domain-containing SOCS box protein SSB-2 Zinc finger protein 36, mRNA (cDNA clone 3.12437 2.35137 1.71 Down NM_011756 MGC:29129 IMAGE:5053664) Nucleoredoxin-like 2, mRNA (cDNA clone 2.125145 1.34742 1.71 Down NM_029173 MGC:49185 IMAGE:5025124) 5.16789 5.945085 1.71 Up NM_133662 Immediate early response 3 (Ier3), mRNA chr1:183951156- 2.92423 3.701195 1.71 Up 183986156_F chr1:183951156-183986156_F Zinc finger, DHHC domain containing 23, mRNA 2.682095 1.90881 1.71 Down AK137472 (cDNA clone MGC:179097 IMAGE:9054089) Histone cluster 1, H2bb, mRNA (cDNA clone 2.766705 1.99178 1.71 Down NM_175664 MGC:151230 IMAGE:40126172) NECAP endocytosis associated 1, mRNA (cDNA 5.02589 4.250345 1.71 Down NM_026267 clone MGC:18995 IMAGE:4013043) 4.78399 4.00879 1.71 Down NM_023716 Tubulin, beta 2B (Tubb2b), mRNA Solute carrier family 22 (organic cation transporter), member 5, mRNA (cDNA clone MGC:36043 2.575795 1.80302 1.71 Down NM_011396 IMAGE:4981427) 8.73499 7.961435 1.71 Down NM_026432 CDNA fis, clone TRACH2016709 Solute carrier family 2 (facilitated glucose transporter), member 6, mRNA (cDNA clone 3.27842 4.05399 1.71 Up NM_172659 MGC:176129 IMAGE:9055780) Von Willebrand factor A domain containing 1, mRNA (cDNA clone MGC:37507 3.2251 2.45435 1.71 Down NM_147776 IMAGE:4985003) chr6:83368261- 4.37522 3.597395 1.71 Down 83407280_F chr6:83368261-83407280_F Calcium regulated heat stable protein 1, mRNA 6.33909 7.109135 1.71 Up NM_025821 (cDNA clone MGC:19027 IMAGE:4166353) 5.71109 4.935835 1.71 Down NM_001038592 Glutaredoxin 2 4.136365 3.36273 1.71 Down NM_206536 CDNA sequence AB124611 (AB124611), mRNA Zinc finger protein 524, mRNA (cDNA clone 6.75979 5.987235 1.71 Down NM_025324 MGC:28722 IMAGE:4458724) 4.322335 3.54484 1.71 Down NM_008354 Interleukin 12 receptor, beta 2 (Il12rb2), mRNA PREDICTED: Mus musculus FERM and PDZ -2.25462 -1.487905 1.7 Up XM_001481294 domain containing 2 (Frmpd2), mRNA RIKEN cDNA A230072E10 gene, mRNA (cDNA -1.17125 -1.936565 1.7 Down NM_198105 clone IMAGE:5252967) chr16:8748982- -1.310335 -2.071935 1.7 Down 8757165_R chr16:8748982-8757165_R -2.175465 -1.409675 1.7 Up NM_172925 CDNA clone IMAGE:4017057 -1.69795 -2.460965 1.7 Down NM_028784 Coagulation factor XIII, A1 subunit (F13a1), mRNA Leukocyte-associated immunoglobulin-like receptor -0.477715 0.28451 1.7 Up NM_178611 (Lair) chr4:155560050- -1.82005 -2.58815 1.7 Down 155570900_R chr4:155560050-155570900_R Glycerol-3-phosphate dehydrogenase 1 (soluble), mRNA (cDNA clone MGC:25620 -1.780705 -2.54419 1.7 Down NM_010271 IMAGE:4194849) chr2:143991240- -1.472845 -0.708655 1.7 Up 143991597_F chr2:143991240-143991597_F Interleukin 11 receptor, alpha chain 2 (Il11ra2), -1.20074 -0.43655 1.7 Up A_55_P1987675 mRNA chr16:23992037- -0.7019 -1.46641 1.7 Down 24001037_R chr16:23992037-24001037_R chr12:70213282- -0.394465 -1.158545 1.7 Down 70225157_R chr12:70213282-70225157_R chr18:3003075- -2.09818 -1.32858 1.7 Up 3016150_F chr18:3003075-3016150_F chr18:46962676- -0.5561 -1.3193 1.7 Down 46962824_F chr18:46962676-46962824_F chr13:48576557- -0.65648 -1.42583 1.7 Down 48581632_F chr13:48576557-48581632_F chr4:82979473- -0.760275 -1.529745 1.7 Down 83035023_R chr4:82979473-83035023_R chr8:26212577- -1.88058 -1.111785 1.7 Up 26218527_F chr8:26212577-26218527_F -1.88707 -1.12104 1.7 Up NM_207545 Vomeronasal 1 receptor, D17 (V1rd17), mRNA V-set and immunoglobulin domain containing 4, mRNA (cDNA clone MGC:36211 -2.32535 -1.55591 1.7 Up A_55_P2012904 IMAGE:4162875) RIKEN cDNA C130079G13 gene -1.438625 -0.671985 1.7 Up NM_177661 (C130079G13Rik), mRNA Nuclear transcription factor, X-box binding 1 -1.89371 -1.124995 1.7 Up A_55_P2027935 (Nfx1), mRNA chr1:182438908- -1.67693 -0.90798 1.7 Up 182449858_R chr1:182438908-182449858_R Kallikrein 1, mRNA (cDNA clone MGC:29118 -1.99151 -1.22391 1.7 Up NM_010639 IMAGE:4922971) -1.61179 -0.84294 1.7 Up NM_001105059 Vomeronasal 2, receptor 62 (Vmn2r62), mRNA SLAM family member 8, mRNA (cDNA clone -1.73845 -0.97262 1.7 Up NM_029084 MGC:37716 IMAGE:5066283) ENSMUST00000 Macrophage receptor with collagenous structure -0.503485 -1.27133 1.7 Down 093911 (Marco), mRNA Carboxypeptidase X 1 (M14 family), mRNA (cDNA -0.3146 0.448785 1.7 Up NM_019696 clone MGC:5707 IMAGE:3593211) -0.770405 -0.00873 1.7 Up U80892 CAG trinucleotide repeat mRNA, partial sequence chr14:65785477- -1.00193 -0.234335 1.7 Up 65815777_F chr14:65785477-65815777_F 0.155065 -0.61096 1.7 Down NM_013922 KRAB-zinc finger protein KID3 (Kid3) chr5:125190100- 0.65015 -0.114815 1.7 Down 125209625_R chr5:125190100-125209625_R 0.22058 0.989895 1.7 Up NM_001163288 Susd1 Protein phosphatase 4, regulatory subunit 4, mRNA 1.013145 0.24423 1.7 Down NM_028980 (cDNA clone MGC:132871 IMAGE:40060480) 3.00324 2.23867 1.7 Down NM_001167743 Slfn8 Zinc finger protein 608, mRNA (cDNA clone 0.91047 0.14708 1.7 Down NM_175751 MGC:183986 IMAGE:9087986) Solute carrier family 25, member 35 (Slc25a35), 1.24504 0.483115 1.7 Down NM_028048 mRNA 1.7084 2.476745 1.7 Up NM_029770 Netrin receptor Unc5h2 (Unc5h2 gene) SH3-domain GRB2-like 3, mRNA (cDNA clone 3.9127 4.680885 1.7 Up NM_017400 MGC:30998 IMAGE:5254139) WSC domain containing 2, mRNA (cDNA clone 1.206065 1.96977 1.7 Up AK049685 MGC:182430 IMAGE:9056324) RIKEN cDNA C130079G13 gene 1.477225 0.71331 1.7 Down NM_177661 (C130079G13Rik), mRNA Acylphosphatase 1, erythrocyte (common) type 0.71266 -0.050425 1.7 Down NM_025421 (Acyp1), mRNA chr10:96082444- 3.30649 2.539985 1.7 Down 96096696_R chr10:96082444-96096696_R ENSMUST00000 1.73679 0.975245 1.7 Down 085789 Zfp420 Lipoyltransferase 1, mRNA (cDNA clone 1.264555 0.498445 1.7 Down NM_001037918 MGC:28431 IMAGE:4038179) 1.3708 2.136185 1.7 Up XR_002334 Lrrc31 chr16:23992037- 1.181955 0.415465 1.7 Down 24001037_F chr16:23992037-24001037_F Myelin basic protein, mRNA (cDNA clone 3.808025 3.038865 1.7 Down NM_010777 MGC:6184 IMAGE:3499588) 3.55638 2.79165 1.7 Down AK011616 Transcribed locus, strongly similar to NP_062240.1 palmitoyl-protein thioesterase 2 [Rattus norvegicus] Sec24 related gene family, member A (S. cerevisiae), mRNA (cDNA clone 3.57735 2.81014 1.7 Down NM_175255 IMAGE:40097170) Sarcosine dehydrogenase (Sardh), nuclear gene 2.116085 2.8797 1.7 Up NM_138665 encoding mitochondrial protein, mRNA Serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1, mRNA (cDNA clone 1.93349 2.699965 1.7 Up NM_080844 MGC:29925 IMAGE:5123932) Ferritin heavy chain 1, mRNA (cDNA clone 11.06584 10.297535 1.7 Down NM_010239 MGC:19422 IMAGE:3488821) 3.901935 3.136145 1.7 Down NR_027965 2310061J03Rik -1.007225 -1.767695 1.69 Down NM_030175 Hhipl2 Transcribed locus, strongly similar to NP_001013808.2 zinc finger protein 187 [Mus -0.36039 -1.11479 1.69 Down AK034331 musculus] -0.63471 -1.39532 1.69 Down AK087815 Transcribed locus ENSMUST00000 Cytochrome P450, family 2, subfamily j, polypeptide -1.305865 -2.062505 1.69 Down 167318 7 (Cyp2j7), mRNA chr5:144517700- -1.411985 -2.168395 1.69 Down 144526071_F chr5:144517700-144526071_F -1.77542 -2.53609 1.69 Down NM_007376 Pregnancy zone protein (Pzp), mRNA chr1:137689555- -2.044725 -1.290765 1.69 Up 137692960_R chr1:137689555-137692960_R chr17:15111725- -0.97471 -1.731775 1.69 Down 15139800_R chr17:15111725-15139800_R chr15:102026122 -1.501765 -2.26076 1.69 Down -102033597_F chr15:102026122-102033597_F chr19:23254618- -1.13072 -0.377135 1.69 Up 23268776_R chr19:23254618-23268776_R chr1:92546371- -1.588595 -0.828575 1.69 Up 92551596_F chr1:92546371-92551596_F -1.88013 -1.12217 1.69 Up AK019926 Transcribed locus F-box protein 8, mRNA (cDNA clone MGC:41115 -0.370715 -1.13154 1.69 Down NM_015791 IMAGE:3468704) chr16:8738782- -1.13715 -0.383695 1.69 Up 8830148_R chr16:8738782-8830148_R Cytochrome P450, family 2, subfamily ab, polypeptide 1, mRNA (cDNA clone MGC:169712 -2.11463 -1.357625 1.69 Up NM_183158 IMAGE:8861107) chr4:11899775- -0.16173 -0.921495 1.69 Down 11931875_R chr4:11899775-11931875_R chr2:165802256- -0.5124 0.24134 1.69 Up 165805186_R chr2:165802256-165805186_R PREDICTED: Mus musculus hypothetical protein -0.541985 -1.30204 1.69 Down A_55_P2177485 LOC100042222 (LOC100042222), mRNA Leucine-rich and death domain containing (Lrdd), 0.38422 -0.37099 1.69 Down A_55_P2085510 mRNA chr1:52507374- 0.673475 1.433205 1.69 Up 52514124_R chr1:52507374-52514124_R 0.993845 1.75171 1.69 Up NM_011770 IKAROS family zinc finger 2 (Ikzf2), mRNA 0.561785 1.320535 1.69 Up NM_001199062 Gm4461 Spectrin domain with coiled-coils 1, mRNA (cDNA 4.288595 5.048835 1.69 Up NM_001029936 clone IMAGE:5374251) 1.33948 2.09883 1.69 Up NM_019453 Mediterranean fever (Mefv), mRNA chr9:96673952- 0.525585 -0.229645 1.69 Down 96674816_F chr9:96673952-96674816_F chr7:35405125- 2.867845 2.10874 1.69 Down 35415223_R chr7:35405125-35415223_R Hermansky-Pudlak syndrome 1 homolog (human) 3.30324 4.06038 1.69 Up NM_019424 (Hps1), mRNA GRP1 (general receptor for phosphoinositides 1)- 2.901245 2.148025 1.69 Down NM_019518 associated scaffold protein (Grasp), mRNA 2.91221 3.667395 1.69 Up NM_010952 Seizure-related 1.16368 0.40703 1.69 Down XM_003086888 LOC546061 PREDICTED: Mus musculus hypothetical protein 2.880325 3.633285 1.69 Up AK135986 LOC100043769 (LOC100043769), mRNA Protein kinase C binding protein 1 (Prkcbp1), 6.19359 5.432335 1.69 Down NM_027230 mRNA Heterogeneous nuclear ribonucleoprotein A3, mRNA (cDNA clone MGC:36649 4.44559 5.202135 1.69 Up NM_198090 IMAGE:5362605) Protein tyrosine phosphatase, receptor type, J (Ptprj), 3.722715 2.967735 1.69 Down NM_001135657 transcript variant 1, mRNA B lymphocyte cell adhesion molecule (Cd22) 3.628885 2.87202 1.69 Down NM_001043317 mRNA, allele Cd22-c chr1:52507332- 6.57874 5.825435 1.69 Down 52514490_R chr1:52507332-52514490_R Potassium channel tetramerisation domain containing 3, mRNA (cDNA clone MGC:90553 4.347635 3.59218 1.69 Down NM_172650 IMAGE:5702630) Trichorhinophalangeal syndrome I (human), mRNA 3.096175 2.33503 1.69 Down NM_032000 (cDNA clone MGC:46754 IMAGE:4951294) Phosphatidylinositol 3-kinase gamma isoform 6.39989 5.643535 1.69 Down NM_020272 (Pik3cg) Phosphodiesterase 1B, Ca2+-calmodulin dependent 5.11934 4.360355 1.69 Down NM_008800 (Pde1b), mRNA 5.01479 4.258275 1.69 Down NR_024599 Gm11346 RNA binding motif protein 6, mRNA (cDNA clone 7.51149 6.751435 1.69 Down NM_029169 MGC:13760 IMAGE:3982861) Myelocytomatosis oncogene, mRNA (cDNA clone 7.64849 6.891335 1.69 Down NM_010849 IMAGE:3962047) Cytochrome P450, family 20, subfamily A, 5.26739 4.50842 1.69 Down A_55_P2096127 polypeptide 1 (Cyp20a1), mRNA Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon, mRNA 5.82499 5.067935 1.69 Down NM_008690 (cDNA clone MGC:31667 IMAGE:49099 Prolyl-tRNA synthetase (mitochondrial)(putative), mRNA (cDNA clone MGC:47008 9.46779 8.713585 1.69 Down A_55_P1954860 IMAGE:3256949) 7.96409 7.203235 1.69 Down NM_053202 Forkhead box P1 (Foxp1), mRNA Transcribed locus, moderately similar to XP_001064639.1 PREDICTED: hypothetical protein 8.21949 7.458435 1.69 Down AK137741 [Rattus norvegicus] -1.27411 -2.020515 1.68 Down NM_001099632 Ring finger protein 39 (Rnf39), mRNA chr18:75513062- -1.42056 -2.173025 1.68 Down 75523889_R chr18:75513062-75523889_R Solute carrier family 16 (monocarboxylic acid -2.050265 -1.298935 1.68 Up BC025441 transporters), member 4 (Slc16a4), mRNA -1.53203 -2.28093 1.68 Down NM_001173460 Sirpb1b chr15:66684765- -0.95717 -1.704275 1.68 Down 66685491_F chr15:66684765-66685491_F chr3:35782698- -1.930355 -1.18595 1.68 Up 35789748_F chr3:35782698-35789748_F chr4:133368314- -1.52146 -0.774215 1.68 Up 133380210_R chr4:133368314-133380210_R chr4:105035450- -0.85496 -1.607485 1.68 Down 105059250_F chr4:105035450-105059250_F chr14:62263564- -1.098965 -1.84342 1.68 Down 62308286_R chr14:62263564-62308286_R -1.5151 -2.26534 1.68 Down NR_040390 A730090N16Rik chr8:124355710- -0.366705 -1.11408 1.68 Down 124401160_F chr8:124355710-124401160_F -1.95347 -1.207125 1.68 Up NM_146308 Olfactory receptor 1356 (Olfr1356), mRNA chr12:88216447- -1.41586 -2.16308 1.68 Down 88224965_F chr12:88216447-88224965_F chrX:137519350- -1.17604 -0.426915 1.68 Up 137534325_R chrX:137519350-137534325_R Alcohol dehydrogenase 1 (class I), mRNA (cDNA -0.630595 -1.37734 1.68 Down NM_007409 clone MGC:18885 IMAGE:4238555) -1.21324 -1.959265 1.68 Down NM_023598 Modulator recognition factor 2 (Mrf2) chr1:92549499- -2.1121 -1.359355 1.68 Up 92550225_R chr1:92549499-92550225_R Fucokinase, mRNA (cDNA clone MGC:47125 -1.47339 -0.72535 1.68 Up A_55_P2031811 IMAGE:4190449) chr13:28975118- -1.73906 -0.99404 1.68 Up 28977236_R chr13:28975118-28977236_R ENSMUST00000 Homeobox, msh-like 1, mRNA (cDNA clone -1.56627 -0.817345 1.68 Up 035914 MGC:25404 IMAGE:4923403) chr14:30758342- -1.533525 -0.783015 1.68 Up 30759669_R chr14:30758342-30759669_R -2.17243 -1.420215 1.68 Up NM_001033177 CDNA clone IMAGE:40092382 -1.352915 -0.605195 1.68 Up NM_146299 Olfactory receptor 745 (Olfr745), mRNA chr9:113648970- -1.50357 -0.758335 1.68 Up 113715170_R chr9:113648970-113715170_R -0.76419 -1.51545 1.68 Down A_55_P1986955 A_55_P1986955 chr6:30983012- -0.31276 -1.062875 1.68 Down 31009987_R chr6:30983012-31009987_R Microrchidia 4, mRNA (cDNA clone MGC:164128 -0.679375 0.06772 1.68 Up NM_029413 IMAGE:40130774) chr1:185808525- -0.92501 -0.175805 1.68 Up 185826139_F chr1:185808525-185826139_F Cathepsin H, mRNA (cDNA clone MGC:6103 1.048405 1.79403 1.68 Up NM_007801 IMAGE:2647229) RIKEN cDNA 6430704M03 gene 0.019035 -0.72545 1.68 Down NM_001142965 (6430704M03Rik), mRNA 1.21213 1.958075 1.68 Up NM_001163616 1810011H11Rik Guanine nucleotide binding protein, alpha stimulating, olfactory type, mRNA (cDNA clone 1.36478 0.612895 1.68 Down NM_177137 MGC:90869 IMAGE:5685967) chr9:96635508- 1.4604 2.20765 1.68 Up 96654148_R chr9:96635508-96654148_R 1.944505 1.19995 1.68 Down NM_153415 Protein-O-mannosyltransferase 2 (Pomt2), mRNA chr5:100849748- 1.568415 0.818105 1.68 Down 100858532_R chr5:100849748-100858532_R chr15:8463685- 2.694225 1.949365 1.68 Down 8494960_R chr15:8463685-8494960_R Tryptophanyl tRNA synthetase 2 (mitochondrial) (Wars2), nuclear gene encoding mitochondrial 1.147765 0.40226 1.68 Down NM_027462 protein, mRNA PREDICTED: Mus musculus AF4/FMR2 family, 4.23799 3.492875 1.68 Down NM_010678 member 3 (Aff3), mRNA 3.6352 2.888815 1.68 Down NM_013524 Fucosyltransferase 7 (Fut7), mRNA Solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10, mRNA 1.49004 2.237375 1.68 Up NM_013770 (cDNA clone MGC:7207 IMAGE:34823 4.129955 3.379515 1.68 Down AK042233 Transcribed locus RAR-related orphan receptor alpha, mRNA (cDNA 5.69639 4.946485 1.68 Down NM_013646 clone MGC:5892 IMAGE:3592667) TRAF-interacting protein, mRNA (cDNA clone 4.82509 5.574085 1.68 Up NM_011634 MGC:13919 IMAGE:3990371) Genetic suppressor element 1, mRNA (cDNA clone 3.504435 2.75905 1.68 Down NM_198671 IMAGE:4486777) 6.90264 6.155185 1.68 Down NM_001195268 Dos 5.72929 6.481585 1.68 Up NM_001164051 Pik3cd 5.97784 5.228585 1.68 Down NM_029766 Denticleless homolog (Drosophila) (Dtl), mRNA ATM interactor, mRNA (cDNA clone MGC:79206 6.59604 5.847035 1.68 Down NM_177700 IMAGE:6847850) Rho guanine nucleotide exchange factor (GEF) 10, 4.82674 4.076265 1.68 Down NM_172751 mRNA (cDNA clone IMAGE:3598550) chr6:54591416- 4.258435 3.510615 1.68 Down 54597566_F chr6:54591416-54597566_F 6.47544 5.729735 1.68 Down NM_001003950 RAB3A interacting protein (Rab3ip), mRNA Esterase 1, mRNA (cDNA clone MGC:18575 -1.85787 -2.59592 1.67 Down NM_007954 IMAGE:4196339) chrX:20389063- -1.363195 -0.62012 1.67 Up 20389702_F chrX:20389063-20389702_F -1.402335 -0.663385 1.67 Up NM_145395 Dual oxidase maturation factor 1 (Duoxa1), mRNA chr3:88323145- -1.007015 -1.745275 1.67 Down 88335770_F chr3:88323145-88335770_F chr5:149751979- -1.81606 -2.55436 1.67 Down 149808240_R chr5:149751979-149808240_R -1.983635 -1.241215 1.67 Up NM_001163318 Gm11744 -1.32145 -0.584765 1.67 Up NM_146936 Olfactory receptor 1417 (Olfr1417), mRNA chr13:34186976- -1.89421 -1.15044 1.67 Up 34210579_R chr13:34186976-34210579_R -1.94937 -1.207345 1.67 Up NM_001177524 Gml Spermatogenesis associated 16 (Spata16), transcript -1.782085 -1.03825 1.67 Up NM_029150 variant 1, mRNA chr18:60812427- -1.485615 -0.747005 1.67 Up 60819775_R chr18:60812427-60819775_R -1.336825 -2.08079 1.67 Down NM_027211 Annexin A13 (Anxa13), mRNA -1.90789 -1.167945 1.67 Up NM_009109 RyR1 mRNA for skeletal muscle ryanodine receptor Heparan sulfate 6-O-sulfotransferase 2, mRNA -0.56491 -1.30781 1.67 Down NM_001077202 (cDNA clone IMAGE:5356211) -0.616585 -1.358705 1.67 Down NM_172701 Organic solute carrier 1 chr8:90000619- -0.48981 -1.226885 1.67 Down 90061169_F chr8:90000619-90061169_F chr5:110891642- -1.76014 -2.49773 1.67 Down 110918642_R chr5:110891642-110918642_R chr2:35828611- -1.2133 -1.954165 1.67 Down 35838083_F chr2:35828611-35838083_F chr8:71526892- -1.95922 -1.217105 1.67 Up 71527500_R chr8:71526892-71527500_R -1.9699 -1.228865 1.67 Up NM_027844 Keratin associated protein 5-2 (Krtap5-2), mRNA -1.29345 -2.03063 1.67 Down NM_028673 Zdbf2 chr17:22815742- -1.09983 -0.357955 1.67 Up 22828592_R chr17:22815742-22828592_R -1.42173 -2.163605 1.67 Down AK005627 Transcribed locus chr2:3703146- -0.68015 -1.421135 1.67 Down 3703715_F chr2:3703146-3703715_F -1.45794 -0.72106 1.67 Up NM_133867 ESP8-like 3 (Eps8l3), mRNA C-type lectin domain family 14, member a, mRNA -1.9048 -1.165375 1.67 Up NM_025809 (cDNA clone MGC:28590 IMAGE:4215467) chr9:68349343- -1.82546 -1.086385 1.67 Up 68411643_R chr9:68349343-68411643_R chr13:41337973- -0.943715 -0.20564 1.67 Up 41379821_R chr13:41337973-41379821_R chr6:126766225- -0.564325 0.177395 1.67 Up 126771309_F chr6:126766225-126771309_F chr14:33923944- -0.84048 -1.583905 1.67 Down 34003394_R chr14:33923944-34003394_R chr14:65431652- -0.78808 -1.527805 1.67 Down 65437902_F chr14:65431652-65437902_F -1.537445 -0.79458 1.67 Up NM_001177484 Gm11559 -1.74225 -0.999055 1.67 Up NM_146597 Olfactory receptor 702 (Olfr702), mRNA chr12:111287772 -1.50355 -0.759645 1.67 Up -111333890_R chr12:111287772-111333890_R Protease, serine, 32, mRNA (cDNA clone -1.977015 -1.234245 1.67 Up NM_027220 MGC:25874 IMAGE:4208033) chr4:59093718- -1.672075 -0.92999 1.67 Up 59108018_F chr4:59093718-59108018_F -0.582245 -1.32235 1.67 Down NM_001081156 TMF1-regulated nuclear protein 1 (Trnp1), mRNA chr12:17438940- -0.84098 -1.581155 1.67 Down 17439119_F chr12:17438940-17439119_F -0.44458 0.2994 1.67 Up NM_146924 Olfactory receptor 476 (Olfr476), mRNA PDZ-LIM protein cypher2s mRNA, complete cds; -0.842385 -1.579535 1.67 Down NM_011918 alternatively spliced chr4:128207615- -0.267375 -1.00472 1.67 Down 128242898_R chr4:128207615-128242898_R -0.60167 0.139035 1.67 Up NM_146878 Olfactory receptor 30 (Olfr30), mRNA Tribbles homolog 2 (Drosophila), mRNA (cDNA 3.756715 3.01664 1.67 Down NM_144551 clone MGC:32449 IMAGE:5043179) ENSMUST00000 Myosin, heavy polypeptide 9, non-muscle, mRNA 1.62999 2.369365 1.67 Up 093991 (cDNA clone IMAGE:4913872) ENSMUST00000 Selection and upkeep of intraepithelial T cells 3 0.456275 -0.287475 1.67 Down 085379 (Skint3), transcript variant 1, mRNA 2.30064 3.044415 1.67 Up XR_104910 5830444B04Rik chr12:77544397- 0.945655 0.209285 1.67 Down 77564122_F chr12:77544397-77564122_F 4.308015 5.045685 1.67 Up NM_011337 Chemokine (C-C motif) ligand 3 (Ccl3), mRNA 2.54764 1.804155 1.67 Down XR_105449 Gm9222 chr11:117835849 2.324125 1.588185 1.67 Down -117842574_F chr11:117835849-117842574_F Zinc finger protein 365, mRNA (cDNA clone 3.557465 2.82043 1.67 Down NM_178679 MGC:189953 IMAGE:9088140) NAD(P)H dehydrogenase, quinone 2, mRNA 2.00486 2.74304 1.67 Up NM_020282 (cDNA clone MGC:41088 IMAGE:1225122) Fibronectin type III and SPRY domain containing 1- like, mRNA (cDNA clone MGC:161352 2.28762 1.546205 1.67 Down NM_176966 IMAGE:40142990) Solute carrier family 25, member 37, mRNA (cDNA 3.165055 2.428375 1.67 Down NM_026331 clone IMAGE:4456736) Interferon induced transmembrane protein 1 (Ifitm1), 7.19689 7.932585 1.67 Up BC090258 transcript variant 1, mRNA Phosphatidylinositol 3-kinase gamma isoform 4.85394 4.11254 1.67 Down NM_020272 (Pik3cg) 3.402435 2.663275 1.67 Down NM_016718 Ninjurin 2 (Ninj2), mRNA chr10:97196521- 5.02834 4.286225 1.67 Down 97207471_F chr10:97196521-97207471_F TBC1 domain family, member 1, mRNA (cDNA 7.80979 7.069385 1.67 Down NM_019636 clone IMAGE:3500261) 5.92734 6.668285 1.67 Up NM_053108 Glutaredoxin (Glrx), mRNA ENSMUST00000 3.018315 2.27894 1.67 Down 047953 Transcribed locus 5.15459 4.412795 1.67 Down AK141707 Ribosomal protein L6 (Rpl6), mRNA Zinc finger protein 78 (Zfp78), transcript variant 3, 2.0735 1.331605 1.67 Down NM_177888 mRNA 3.015335 2.27911 1.67 Down NM_001159636 Wdsub1 Phosphoinositide-3-kinase adaptor protein 1 1.93598 2.67207 1.67 Up NM_031376 (Pik3ap1), mRNA Cleavage stimulation factor, 3 pre-RNA, subunit 1, 7.72414 6.984185 1.67 Down NM_024199 mRNA (cDNA clone MGC:6802 IMAGE:2648192) RIKEN cDNA 1700025G04 gene, mRNA (cDNA 4.99759 4.25838 1.67 Down NM_197990 clone MGC:28137 IMAGE:3981517) Kruppel-like factor 10, mRNA (cDNA clone 5.70899 4.966035 1.67 Down NM_013692 MGC:7000 IMAGE:3155247) Zinc finger CCCH type containing 12A (Zc3h12a), 3.71701 2.97908 1.67 Down NM_153159 mRNA 6.72049 5.976685 1.67 Down NM_010818 CD200 antigen (Cd200), mRNA chr2:60581618- -2.0356 -1.307505 1.66 Up 60589907_F chr2:60581618-60589907_F chr8:85952719- -1.59419 -2.32351 1.66 Down 85958369_R chr8:85952719-85958369_R -1.56253 -2.29405 1.66 Down NM_146117 Leucine rich repeat containing 26 (Lrrc26), mRNA ENSMUST00000 Adaptor-related protein complex AP-4, sigma 1 -1.802515 -1.067935 1.66 Up 068448 (Ap4s1), mRNA chr14:78214602- -1.660155 -0.93213 1.66 Up 78225827_R chr14:78214602-78225827_R chr5:77188300- -0.738865 -1.472435 1.66 Down 77205150_F chr5:77188300-77205150_F Spermidine/spermine N1-acetyl transferase 2 (Sat2), -2.024165 -1.28982 1.66 Up NM_026991 mRNA chr7:134620707- -1.255535 -1.983255 1.66 Down 134626739_R chr7:134620707-134626739_R -0.70394 0.025305 1.66 Up TC1702006 TC1702006 chr2:80338640- -0.579235 -1.314655 1.66 Down 80339980_R chr2:80338640-80339980_R -0.8547 -1.585455 1.66 Down NAP113341-1 Olfactory receptor 741 (Olfr741), mRNA -1.08089 -0.34816 1.66 Up A_55_P2065351 A_55_P2065351 -1.374465 -0.64627 1.66 Up TC1626843 TC1626843 -1.19015 -0.46264 1.66 Up NM_146943 Olfactory receptor 347 (Olfr347), mRNA chr15:79276925- -1.67414 -0.945945 1.66 Up 79286500_R chr15:79276925-79286500_R PREDICTED: Mus musculus predicted gene, -1.00305 -1.7311 1.66 Down A_55_P2029791 EG626854 (EG626854), mRNA chr15:83266264- -0.43619 -1.17079 1.66 Down 83294664_F chr15:83266264-83294664_F chr15:79709500- -0.160135 -0.8906 1.66 Down 79714700_R chr15:79709500-79714700_R Jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae), mRNA (cDNA clone -1.209825 -1.94011 1.66 Down A_55_P1962688 IMAGE:3488682) chr17:9889983- -1.580705 -0.84963 1.66 Up 9919633_F chr17:9889983-9919633_F Erythrocyte protein band 4.1-like 4a, mRNA (cDNA -1.209465 -0.480955 1.66 Up NM_013512 clone MGC:6099 IMAGE:3490326) -1.05091 -0.32338 1.66 Up AK141187 Transcribed locus -1.495065 -0.765465 1.66 Up NM_146882 Olfactory receptor 874 (Olfr874), mRNA ENSMUST00000 SLIT and NTRK-like family, member 4, mRNA -1.08237 -0.35021 1.66 Up 027895 (cDNA clone MGC:144017 IMAGE:40096585) chr14:99656262- -0.45471 0.27825 1.66 Up 99656858_R chr14:99656262-99656858_R 0.116125 -0.61422 1.66 Down XM_001476568 LOC100046658 chr5:110158475- 0.35236 -0.37834 1.66 Down 110223700_F chr5:110158475-110223700_F 0.19909 -0.53085 1.66 Down NM_028053 Transmembrane protein 38B (Tmem38b), mRNA 0.358145 1.08565 1.66 Up NM_026639 ADP-ribosyltransferase 4 (Art4), mRNA 0.335765 -0.397555 1.66 Down NM_001081124 MAP7 domain containing 2 (Mtap7d2), mRNA 2.10622 2.835665 1.66 Up NM_010669 Keratin 6B (Krt6b), mRNA chr9:96664617- 4.312075 5.042385 1.66 Up 96683617_R chr9:96664617-96683617_R Inter-alpha trypsin inhibitor, heavy chain 1, mRNA 0.495745 1.226665 1.66 Up NM_008406 (cDNA clone MGC:36127 IMAGE:5099284) 3.12686 3.85534 1.66 Up NM_010052 Delta-like 1 homolog (Drosophila) (Dlk1), mRNA Family with sequence similarity 108, member B 6.89754 7.626435 1.66 Up NM_146096 (Fam108b), mRNA RIKEN cDNA 0610010O12 gene, mRNA (cDNA 2.30271 3.0365 1.66 Up NM_001081365 clone MGC:41247 IMAGE:1195860) chr9:41184479- 1.306205 0.57408 1.66 Down 41240162_F chr9:41184479-41240162_F Interferon-gamma (MuIFN-gamma) mRNA 5.92714 6.655635 1.66 Up NM_008337 sequence 2.85207 2.12314 1.66 Down NM_001160326 Serp2 4.61854 5.346335 1.66 Up NM_146064 Sterol O-acyltransferase 2 (Soat2), mRNA 0.52121 -0.207175 1.66 Down NM_010272 Growth/differentiation factor 11 UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast), mRNA (cDNA clone 5.26449 4.530625 1.66 Down NM_028276 MGC:105191 IMAGE:30625504) Microtubule associated serine/threonine kinase 1 2.08184 1.348395 1.66 Down NM_019945 (Mast1), mRNA chr18:77291264- 2.404665 1.67162 1.66 Down 77299664_F chr18:77291264-77299664_F UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4, mRNA (cDNA 1.82916 1.09588 1.66 Down NM_019804 clone MGC:35921 IMAGE:5026168) 3.334 2.60269 1.66 Down AK047332 B930049P21Rik Interferon induced transmembrane protein 1 (Ifitm1), 7.34519 8.078185 1.66 Up NM_001112715 transcript variant 1, mRNA Fatty acid amide hydrolase, mRNA (cDNA clone 5.02339 4.29156 1.66 Down NM_010173 MGC:11634 IMAGE:3595191) chr14:65430484- 4.80699 4.075165 1.66 Down 65432413_R chr14:65430484-65432413_R 2.963565 2.234735 1.66 Down NM_025918 Coiled-coil domain containing 43 (Ccdc43), mRNA ENSMUST00000 Sushi-repeat-containing protein, X-linked 2 (Srpx2), 0.527065 -0.20561 1.66 Down 145198 transcript variant 1, mRNA chr9:14460976- 7.23739 6.510035 1.66 Down 14488051_F chr9:14460976-14488051_F 5.24164 4.508115 1.66 Down NM_027884 Tns1 8.69139 7.964285 1.66 Down NM_011653 Tubulin, alpha 1A (Tuba1a), mRNA Transmembrane protein 8 (five membrane-spanning domains), mRNA (cDNA clone MGC:11794 2.758095 2.02869 1.66 Down NM_021793 IMAGE:3595205) Solute carrier family 30 (zinc transporter), member 4 6.39339 5.659685 1.66 Down NM_011774 (Slc30a4), mRNA Spermatogenesis associated, serine-rich 2 (Spats2), 2.745295 2.014925 1.66 Down NM_139140 mRNA -1.529995 -2.2535 1.65 Down NM_001163836 Pabpc6 chr17:21177225- -1.2776 -0.55275 1.65 Up 21187525_R chr17:21177225-21187525_R chr17:56687541- -0.46079 0.258285 1.65 Up 56694616_F chr17:56687541-56694616_F Cysteine-rich hydrophobic domain 1, mRNA (cDNA -1.401135 -2.121675 1.65 Down NM_009767 clone MGC:170357 IMAGE:8861752) chr5:22056218- -1.32729 -2.05211 1.65 Down 22206995_F chr5:22056218-22206995_F ENSMUST00000 Rab interacting lysosomal protein, mRNA (cDNA -1.60192 -2.32387 1.65 Down 112103 clone IMAGE:1429973) ENSMUST00000 -0.439535 -1.166075 1.65 Down 116584 Mrpl39 chr2:176583825- -1.266365 -1.98571 1.65 Down 176714400_F chr2:176583825-176714400_F Glypican 2 (cerebroglycan), mRNA (cDNA clone -1.43759 -0.712515 1.65 Up NM_172412 IMAGE:40136387) chr17:46058814- -1.002135 -0.279225 1.65 Up 46059304_F chr17:46058814-46059304_F chr1:81657350- -0.884735 -1.610765 1.65 Down 81765250_F chr1:81657350-81765250_F Nicotinamide nucleotide transhydrogenase, mRNA -1.43088 -2.150345 1.65 Down NM_008710 (cDNA clone MGC:6038 IMAGE:3601702) chr2:127988295- -1.523925 -2.247025 1.65 Down 128194920_F chr2:127988295-128194920_F ENSMUST00000 Baculoviral IAP repeat-containing 3, mRNA (cDNA -0.74258 -1.46067 1.65 Down 160513 clone MGC:18386 IMAGE:3661563) ENSMUST00000 -0.863835 -1.5866 1.65 Down 055994 ENSMUST00000055994 chr11:117768049 -1.44606 -0.72094 1.65 Up -117807949_F chr11:117768049-117807949_F Adrenomedullin 2, mRNA (cDNA clone -1.247805 -0.528645 1.65 Up NM_182928 MGC:106050 IMAGE:4948766) -1.720395 -0.996 1.65 Up A_55_P2078690 A_55_P2078690 chr14:77006215- -0.92433 -0.198815 1.65 Up 77063293_R chr14:77006215-77063293_R -0.815895 -1.5412 1.65 Down NM_033175 Late cornified envelope 3C (Lce3c), mRNA Psoriasis susceptibility 1 candidate 2 (human) -1.240625 -1.96195 1.65 Down NM_020576 (Psors1c2), mRNA -1.32225 -2.04609 1.65 Down A_55_P2132202 A_55_P2132202 Tripartite motif-containing 38, mRNA (cDNA clone -0.87778 -0.159145 1.65 Up NM_001029935 MGC:183747 IMAGE:9087747) WNT1 inducible signaling pathway protein 3 -1.95688 -1.23462 1.65 Up NM_001127376 (Wisp3), mRNA chr2:22753100- -2.36701 -1.644455 1.65 Up 22780375_R chr2:22753100-22780375_R chr8:37582187- -0.848975 -1.57158 1.65 Down 37621987_F chr8:37582187-37621987_F chr7:99879368- -0.117595 -0.84413 1.65 Down 99889978_F chr7:99879368-99889978_F -0.497015 0.22708 1.65 Up NM_010020 Dopamine transporter (Dat) PREDICTED: Mus musculus cDNA sequence -0.423855 0.297825 1.65 Up A_55_P2037783 BC040756 (BC040756), mRNA chr4:8865575- -0.573925 0.149295 1.65 Up 8899400_R chr4:8865575-8899400_R Peroxisomal biogenesis factor 11 gamma (Pex11c), 0.05568 0.778855 1.65 Up AK165461 mRNA 0.215025 -0.51091 1.65 Down NR_027966 4930429B21Rik chr1:69531191- 0.669135 1.395575 1.65 Up 69570566_R chr1:69531191-69570566_R G protein-coupled receptor 97, mRNA (cDNA clone 0.434835 1.154415 1.65 Up NM_173036 IMAGE:4223741) Leucine rich repeat containing 49 (Lrrc49), transcript 0.76205 0.03573 1.65 Down NM_145616 variant 2, mRNA 0.88796 0.166055 1.65 Down AK013682 Transcribed locus Lymphocyte antigen 6 complex, locus K (Ly6k), 4.614575 3.89253 1.65 Down NM_029627 mRNA 0.87142 1.591165 1.65 Up NM_001161817 Myo1b chr12:82457625- 0.80054 0.0755 1.65 Down 82476325_R chr12:82457625-82476325_R chr17:27479404- 2.68027 3.40566 1.65 Up 27481770_F chr17:27479404-27481770_F 1.15907 1.880895 1.65 Up AK081638 Transcribed locus Zinc finger protein 667, mRNA (cDNA clone 1.802635 1.079175 1.65 Down NM_001024928 MGC:176113 IMAGE:9055764) 1.315955 2.03663 1.65 Up NM_010285 Growth hormone releasing hormone (Ghrh), mRNA Laminin, beta 3, mRNA (cDNA clone MGC:5994 3.378725 4.103845 1.65 Up NM_008484 IMAGE:3592888) Membrane bound O-acyltransferase domain 5.12874 4.410495 1.65 Down NM_026037 containing 2 (Mboat2), transcript variant 1, mRNA 3.941155 4.660485 1.65 Up NM_007601 Calpain 3 (Canp3) mRNA, alternatively spliced Junctional sarcoplasmic reticulum protein 1 (Jsrp1), 3.250915 3.972105 1.65 Up NM_028001 mRNA Colony stimulating factor 1 (macrophage), mRNA 1.474045 0.752855 1.65 Down NM_001113530 (cDNA clone IMAGE:5342906) 1.64998 0.929495 1.65 Down NM_001163780 Ick 3.72884 3.002425 1.65 Down NM_018818 Choroidermia (Chm), mRNA 2.030055 1.30853 1.65 Down TC1713419 TC1713419 ENSMUST00000 Selenocysteine lyase, mRNA (cDNA clone 2.93147 2.206415 1.65 Down 136648 MGC:29386 IMAGE:5054691) ENSMUST00000 8.27059 7.543835 1.65 Down 109462 CDNA sequence BC024814 (BC024814), mRNA WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2, mRNA (cDNA clone 0.82169 1.54581 1.65 Up NM_181819 MGC:130508 IMAGE:40047070) Potassium large conductance calcium-activated channel, subfamily M, beta member 4 (Kcnmb4), 2.979085 2.25838 1.65 Down NM_021452 mRNA 6.27899 5.552435 1.65 Down NM_001204912 2410017P09Rik Proteasome (prosome, macropain) assembly 5.91149 5.187385 1.65 Down NM_001101430 chaperone 4 (Psmg4), transcript variant 2, mRNA Solute carrier family 4, sodium bicarbonate 8.21234 7.488285 1.65 Down NM_001081162 transporter-like, member 11 (Slc4a11), mRNA Avian reticuloendotheliosis viral (v-rel) oncogene related B, mRNA (cDNA clone MGC:25383 6.47784 5.757135 1.65 Down NM_009046 IMAGE:4485540) 7.20879 6.484785 1.65 Down NM_026741 Zinc finger protein 579 (Zfp579), mRNA B9 protein domain 1, mRNA (cDNA clone 4.96904 4.24271 1.65 Down NM_013717 MGC:5687 IMAGE:3483517) Tumor necrosis factor receptor superfamily, member 5.07454 4.349295 1.65 Down NM_021349 13b (Tnfrsf13b), mRNA AFG3(ATPase family gene 3)-like 1 (yeast) 2.903325 3.62147 1.65 Up NM_054070 (Afg3l1), mRNA Small nuclear ribonucleoprotein 40 (U5) (Snrnp40), 7.03519 6.314835 1.65 Down NM_025645 mRNA chr14:65205583- -0.97688 -1.69233 1.64 Down 65205906_R chr14:65205583-65205906_R chr8:126278269- -1.252615 -0.537845 1.64 Up 126291621_F chr8:126278269-126291621_F chr19:7458725- -1.300005 -2.014845 1.64 Down 7474825_F chr19:7458725-7474825_F chr2:94017095- -1.89269 -1.178905 1.64 Up 94019092_R chr2:94017095-94019092_R chr15:82037381- -0.975885 -1.69068 1.64 Down 82048125_R chr15:82037381-82048125_R chr19:16078625- -1.95201 -2.66479 1.64 Down 16110246_R chr19:16078625-16110246_R Tubulin, alpha-like 3, mRNA (cDNA clone -1.753375 -2.46648 1.64 Down NM_001033879 MGC:182548 IMAGE:9056442) Rho GTPase activating protein 29, mRNA (cDNA -0.596205 -1.308275 1.64 Down NM_172525 clone IMAGE:4950125) chr2:174088550- -0.324705 0.386705 1.64 Up 174109425_R chr2:174088550-174109425_R Potassium voltage-gated channel, subfamily H (eag- -1.158805 -1.869775 1.64 Down NM_001037712 related), member 6 (Kcnh6), mRNA chr8:49866197- -1.43376 -0.72159 1.64 Up 49866841_R chr8:49866197-49866841_R chr16:84708005- -0.5045 -1.216585 1.64 Down 84708675_R chr16:84708005-84708675_R chr9:31834945- -1.18436 -1.894445 1.64 Down 32015745_R chr9:31834945-32015745_R Glial fibrillary acidic protein [Mus musculus], -0.679205 -1.39633 1.64 Down NM_010277 mRNA sequence -0.59892 -1.315455 1.64 Down NM_001160399 Ccdc112 -2.00635 -1.29106 1.64 Up A_55_P2012176 Spermatogenesis associated 6 (Spata6), mRNA chr18:6144775- -1.538585 -0.822365 1.64 Up 6202232_R chr18:6144775-6202232_R -0.255795 -0.96786 1.64 Down NM_008909 Periplakin (Ppl), mRNA -0.285225 0.428195 1.64 Up NM_019982 Acupuncture induced gene 1 chr2:22782700- -1.190305 -1.90067 1.64 Down 22801900_F chr2:22782700-22801900_F Coagulation factor II (thrombin) receptor-like 2 -1.283545 -0.568785 1.64 Up NM_010170 (F2rl2), mRNA -0.37665 0.334755 1.64 Up AK157102 Gm10753 Immunoglobulin superfamily, member 6 (Igsf6), -0.8662 -1.583695 1.64 Down NM_030691 mRNA -0.80037 -1.5159 1.64 Down NM_001161765 Fmo5 Tubulin tyrosine ligase-like family, member 6, mRNA (cDNA clone MGC:178686 -0.97994 -0.262075 1.64 Up NM_172799 IMAGE:9053678) -0.510725 -1.22076 1.64 Down NM_029196 4930544O15Rik chr2:71576218- -1.447585 -0.732975 1.64 Up 71603818_F chr2:71576218-71603818_F chr13:115071535 -1.75355 -1.036265 1.64 Up -115074139_R chr13:115071535-115074139_R -1.390725 -0.677055 1.64 Up NM_054044 G protein-coupled receptor 124 (Gpr124), mRNA chr19:56580315- -0.54005 0.17707 1.64 Up 56592490_R chr19:56580315-56592490_R -0.487395 0.22548 1.64 Up NM_030554 RAB27B (Yrcmrab27b) -0.29427 0.416315 1.64 Up NM_145209 Oligoadenylate synthetase-like protein-2 Sarcospan, mRNA (cDNA clone MGC:36063 -1.73514 -1.023315 1.64 Up NM_010656 IMAGE:5344514) -0.231555 -0.943825 1.64 Down NM_027715 Otud1 chr5:137392195- -1.536675 -0.81952 1.64 Up 137426421_R chr5:137392195-137426421_R -0.59587 -1.311975 1.64 Down NM_025973 Progastricsin (pepsinogen C) (Pgc), mRNA -0.94966 -0.232075 1.64 Up TC1695262 TC1695262 chr9:32156266- 1.671705 2.38544 1.64 Up 32169196_F chr9:32156266-32169196_F Progesterone immunomodulatory binding factor 1 0.381005 -0.330515 1.64 Down NM_029454 (Pibf1), transcript variant 2, mRNA chr4:129488462- 0.372425 -0.339415 1.64 Down 129516410_F chr4:129488462-129516410_F Protein kinase, membrane associated tyrosine/threonine 1, mRNA (cDNA clone 1.457585 0.74746 1.64 Down A_66_P102159 MGC:35824 IMAGE:2609421) 1.060355 0.34343 1.64 Down NM_023370 Cadherin 23 chr8:34627209- 2.245125 1.52956 1.64 Down 34667814_F chr8:34627209-34667814_F 0.140535 0.858145 1.64 Up NR_033549 Gm11190 SERTA domain containing 3, mRNA (cDNA clone 3.260015 3.970985 1.64 Up NM_133210 MGC:41372 IMAGE:1364881) 3.102365 2.38445 1.64 Down NM_172603 Phf11-4 (Phf11-4) Transmembrane 6 superfamily member 1 (Tm6sf1), 1.97265 2.686575 1.64 Up NM_145375 mRNA PREDICTED: Mus musculus hypothetical 2.62543 1.914925 1.64 Down AK043809 LOC670912 (LOC670912), mRNA 2.32513 1.61167 1.64 Down NM_011270 Rh blood group, D antigen (Rhd), mRNA chr7:88668948- 0.571875 -0.138385 1.64 Down 88678046_F chr7:88668948-88678046_F 4.67629 3.964125 1.64 Down NM_019449 Unc-93 homolog B1 (C. elegans) (Unc93b1), mRNA Chromatin modifying protein 2B, mRNA (cDNA 4.55449 3.837055 1.64 Down NM_026879 clone MGC:67644 IMAGE:6414077) 4.287385 3.57608 1.64 Down NM_001195006 Ndrg4 DNA fragmentation factor, alpha subunit (Dffa), 3.315905 2.601285 1.64 Down NM_001025296 transcript variant 2, mRNA Ring finger and SPRY domain containing 1 5.66584 4.951935 1.64 Down NM_026274 (Rspry1), mRNA Transformed mouse 3T3 cell double minute 2 8.71494 8.003185 1.64 Down NM_010786 (Mdm2), mRNA Leucine rich repeat and coiled-coil domain containing 1, mRNA (cDNA clone MGC:170362 1.258215 0.540445 1.64 Down NM_028915 IMAGE:8861757) 4.88429 4.16784 1.64 Down NR_028432 2210013O21Rik Solute carrier family 41, member 1, mRNA (cDNA 5.46729 4.753985 1.64 Down NM_173865 clone IMAGE:4504894) chr6:86776350- 2.643455 1.928945 1.64 Down 86799379_R chr6:86776350-86799379_R 5.93624 5.223235 1.64 Down NM_008802 CAMP phosphodiesterase 7A1 RIKEN cDNA C130090K23 gene, mRNA (cDNA 2.704045 1.98661 1.64 Down NM_181323 clone MGC:27925 IMAGE:3584006) 4.84659 4.137065 1.64 Down NM_027258 Rnf157 5.05729 4.339535 1.64 Down NM_011764 Zinc finger protein 90 (Zfp90), mRNA Solute carrier family 4 (anion exchanger), member 8, mRNA (cDNA clone MGC:40625 2.80207 2.087765 1.64 Down NM_021530 IMAGE:5401143) HLA-B associated transcript 5, mRNA (cDNA clone 3.65125 4.367125 1.64 Up NM_178592 MGC:19234 IMAGE:2648618) Glucosamine-6-phosphate deaminase 2, mRNA 5.34879 4.634585 1.64 Down NM_001038015 (cDNA clone MGC:8283 IMAGE:3593102) Expressed sequence AI481105, mRNA (cDNA clone 6.44554 5.730985 1.64 Down NM_001033196 IMAGE:4168084) chr7:28592214- 1.17447 0.456965 1.64 Down 28605984_F chr7:28592214-28605984_F ADP-ribosylation factor-like 6, mRNA (cDNA clone 2.786585 2.072195 1.64 Down NM_019665 MGC:27826 IMAGE:3484868) Debranching enzyme homolog 1 (S. cerevisiae), 4.81009 4.09346 1.64 Down NM_031403 mRNA (cDNA clone MGC:6384 IMAGE:3501390) Bardet-Biedl syndrome 4 (human), mRNA (cDNA 3.866715 3.14946 1.64 Down NM_175325 clone MGC:175658 IMAGE:40131074) -0.703525 -1.407735 1.63 Down AK016350 Transcribed locus -1.69045 -0.982525 1.63 Up NM_001077633 Demilune cell and parotid protein 3 (Dcpp3), mRNA ENSMUST00000 V-myc myelocytomatosis viral oncogene homolog 1, -1.863095 -1.157375 1.63 Up 043406 lung carcinoma derived (avian) (Mycl1), mRNA chr7:26202452- -1.48584 -2.191695 1.63 Down 26224557_F chr7:26202452-26224557_F -1.188285 -0.486245 1.63 Up NM_001111094 Butyrophilin-like 1 (Btnl1), mRNA Class I MHC receptor KLRA5 (Klra5) mRNA, -0.445225 0.25644 1.63 Up NM_008463 complete cds; alternatively spliced -1.15567 -1.86394 1.63 Down AK079655 Transcribed locus chr14:78924115- -0.95645 -1.660365 1.63 Down 78938125_F chr14:78924115-78938125_F chr13:62152594- -0.0771 0.627515 1.63 Up 62153041_R chr13:62152594-62153041_R -1.757945 -1.049785 1.63 Up A_55_P1957430 A_55_P1957430 chr5:105000678- -0.652055 -1.353475 1.63 Down 105015290_F chr5:105000678-105015290_F -1.05197 -0.347015 1.63 Up A_55_P2140745 A_55_P2140745 -1.471525 -2.17842 1.63 Down A_55_P2016213 Olfactory receptor 586 (Olfr586), mRNA Coiled-coil and C2 domain containing 2A, mRNA -0.856095 -1.55829 1.63 Down NM_172274 (cDNA clone MGC:40866 IMAGE:5369681) G protein-coupled receptor 133, mRNA (cDNA -0.6845 -1.386165 1.63 Down NM_001081342 clone MGC:184061 IMAGE:9088050) Basic leucine zipper transcription factor, ATF-like 2, mRNA (cDNA clone MGC:37488 -0.589985 0.112485 1.63 Up NM_028967 IMAGE:4984403) NLR family, pyrin domain containing 4E, mRNA -1.769895 -1.062915 1.63 Up NM_001004194 (cDNA clone MGC:170947 IMAGE:8862342) G-protein coupled receptor 119, mRNA (cDNA -1.87391 -1.16987 1.63 Up NM_181751 clone MGC:144413 IMAGE:40101841) -1.95043 -1.24768 1.63 Up NM_001012307 Defensin, alpha 1 (Defa1), mRNA chr2:84422868- -2.00652 -1.30226 1.63 Up 84429877_F chr2:84422868-84429877_F Splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) -1.42614 -0.717 1.63 Up A_55_P2164196 (Sfpq), mRNA chr11:76400207- -0.798895 -0.092685 1.63 Up 76434732_R chr11:76400207-76434732_R ENSMUST00000 Slowmo homolog 2 (Drosophila), mRNA (cDNA -0.60724 -1.3132 1.63 Down 132973 clone MGC:30391 IMAGE:4235395) Glycine cleavage system protein H (aminomethyl carrier), mRNA (cDNA clone MGC:25958 -0.520665 -1.228565 1.63 Down NM_026572 IMAGE:4239181) -1.181055 -0.47893 1.63 Up NM_146361 Olfactory receptor 557 (Olfr557), mRNA chr10:109653855 -1.94132 -1.237385 1.63 Up -109858347_R chr10:109653855-109858347_R ENSMUST00000 -0.235355 -0.94 1.63 Down 109715 GPN-loop GTPase 2 (Gpn2), mRNA Kallikrein 1-related pepidase b4, mRNA (cDNA -0.440435 0.2627 1.63 Up NM_010915 clone MGC:25388 IMAGE:4911885) chr11:18753941- -0.805225 -0.0999 1.63 Up 18760118_R chr11:18753941-18760118_R chr3:151746091- 0.506545 1.2136 1.63 Up 151753763_R chr3:151746091-151753763_R 0.36026 -0.34419 1.63 Down AK141188 CDNA clone IMAGE:40091165 1.200005 1.9074 1.63 Up XM_001472841 Gm10505 PREDICTED: Mus musculus predicted gene, 0.33502 1.03564 1.63 Up BC054084 EG666464 (EG666464), mRNA Transmembrane 6 superfamily member 1 (Tm6sf1), 2.12985 2.833895 1.63 Up NM_145375 mRNA chr8:34646787- 2.487345 1.783535 1.63 Down 34680312_F chr8:34646787-34680312_F chrX:50400250- 2.527895 1.82112 1.63 Down 50410825_F chrX:50400250-50410825_F Glutamic acid decarboxylase 2, mRNA (cDNA clone 3.203555 2.50044 1.63 Down NM_008078 MGC:25362 IMAGE:4482097) 3.00643 2.29898 1.63 Down NM_011976 Semaphorin subclass 4 member G (sema4g) Z-DNA binding protein 1, mRNA (cDNA clone 3.976095 3.26878 1.63 Down NM_021394 MGC:28261 IMAGE:4007636) BEN domain containing 6, mRNA (cDNA clone 3.752595 3.04413 1.63 Down NM_177235 MGC:67495 IMAGE:5707039) 4.17884 4.883435 1.63 Up NM_009401 Tumor necrosis factor receptor superfamily, member 8 (Tnfrsf8), mRNA ENSMUST00000 Docking protein 2, mRNA (cDNA clone MGC:8067 1.187485 0.482295 1.63 Down 150973 IMAGE:3587682) Transcribed locus, strongly similar to XP_001473470.1 PREDICTED: hypothetical protein 4.33295 3.63247 1.63 Down AK016231 [Mus musculus] Nephronophthisis 3 (adolescent) (Nphp3), transcript 1.262535 0.555965 1.63 Down NM_028721 variant 1, mRNA 5.07824 4.369135 1.63 Down NM_001012402 CDNA clone IMAGE:9053983 chr5:139230332- 4.22728 3.5183 1.63 Down 139230823_R chr5:139230332-139230823_R 3.81146 3.10514 1.63 Down NM_181400 WD repeat domain 47 (Wdr47), mRNA RIKEN cDNA 4930430F08 gene, mRNA (cDNA 4.83484 4.132975 1.63 Down NM_175128 clone MGC:100306 IMAGE:30630155) Mitochondrial ribosomal protein L38, mRNA 4.90394 4.196135 1.63 Down NM_024177 (cDNA clone MGC:41062 IMAGE:1493919) Thiopurine methyltransferase, mRNA (cDNA clone 2.796345 2.092645 1.63 Down NM_016785 MGC:35956 IMAGE:5098857) NADH dehydrogenase (ubiquinone) 1 beta 9.60479 8.901535 1.63 Down NM_026061 subcomplex 8 (Ndufb8), mRNA RNA binding motif, single stranded interacting protein 2, mRNA (cDNA clone MGC:13764 4.321025 3.61742 1.63 Down NM_001039080 IMAGE:4207338) chr12:86415200- 3.060055 2.357425 1.63 Down 86415483_F chr12:86415200-86415483_F C-terminal binding protein 2, mRNA (cDNA clone 0.48019 1.183095 1.63 Up NM_009980 MGC:27651 IMAGE:4511826) WSC domain containing 2, mRNA (cDNA clone 3.8891 4.593315 1.63 Up NM_177292 MGC:182430 IMAGE:9056324) 8.50314 7.799935 1.63 Down NAP029816-1 Zona pellucida glycoprotein 3 (Zp3), mRNA SPATA7 isoform mRNA, complete cds, 1.365775 0.659085 1.63 Down NM_178914 alternatively spliced Speckle-type POZ protein-like, mRNA (cDNA clone 2.91067 2.20383 1.63 Down NM_029773 MGC:130583 IMAGE:40056321) DNA replication helicase 2 homolog (yeast), mRNA 3.07799 2.376505 1.63 Down NM_177372 (cDNA clone IMAGE:5376010) Gamma-glutamyl hydrolase, mRNA (cDNA clone 4.91744 4.209985 1.63 Down NM_010281 MGC:13786 IMAGE:4223953) E1A binding protein p300, mRNA (cDNA clone 4.84344 4.13849 1.63 Down NM_177821 MGC:178532 IMAGE:9053524) Syndecan binding protein, mRNA (cDNA clone 4.01613 4.719835 1.63 Up NM_016807 MGC:30224 IMAGE:4017442) NADH dehydrogenase (ubiquinone) Fe-S protein 8 6.66559 5.962985 1.63 Down NM_144870 (Ndufs8), mRNA 2.60296 1.9018 1.63 Down NM_001024712 Alpha16-takusan Protein phosphatase 2C, magnesium dependent, catalytic subunit, mRNA (cDNA clone 3.14912 2.4433 1.63 Down NM_001098230 MGC:170617 IMAGE:8862012) 4.214555 4.923835 1.63 Up NM_001033419 Carcinoembryonic antigen-related cell adhesion molecule 16, mRNA (cDNA clone MGC:176048 IMAGE:9055699) chrX:120976609- -1.513225 -0.815475 1.62 Up 120977281_F chrX:120976609-120977281_F PREDICTED: Mus musculus hypothetical protein -1.60122 -0.902775 1.62 Up AK139872 LOC100040155 (LOC100040155), mRNA Transcribed locus, strongly similar to NP_001121558.1 ankyrin repeat and sterile alpha -1.304275 -1.999985 1.62 Down AK036288 motif domain containing 1B [Mus muscul chr1:85304494- -0.280355 -0.976865 1.62 Down 85305390_R chr1:85304494-85305390_R chr15:83281223- -1.30766 -0.61242 1.62 Up 83284791_R chr15:83281223-83284791_R -2.095625 -1.397855 1.62 Up A_66_P120230 Cyclin M3 (Cnnm3), transcript variant 1, mRNA -1.92197 -1.224305 1.62 Up NM_001042503 Tripartite motif-containing 71 (Trim71), mRNA -0.9989 -1.692235 1.62 Down NM_147089 Olfactory receptor 572 (Olfr572), mRNA Pregnancy specific glycoprotein 16, mRNA (cDNA -1.77643 -2.47534 1.62 Down BC030357 clone MGC:40798 IMAGE:5367680) Transcribed locus, strongly similar to NP_671511.2 T-cell activation GTPase activating protein 1 [Mus -1.55674 -2.249605 1.62 Down BY763003 musculus] ENSMUST00000 -1.82796 -1.13226 1.62 Up 096325 Gm960 chr14:33895294- -1.28349 -0.59131 1.62 Up 33923644_R chr14:33895294-33923644_R chr14:20893694- -1.062505 -1.754285 1.62 Down 20903726_R chr14:20893694-20903726_R chr8:40257009- -0.552835 -1.24824 1.62 Down 40258777_F chr8:40257009-40258777_F chr5:14923900- -1.06597 -1.765785 1.62 Down 15062725_F chr5:14923900-15062725_F chrX:150159252- -1.15372 -1.85338 1.62 Down 150181275_R chrX:150159252-150181275_R Olfactory receptor 107, mRNA (cDNA clone -1.438325 -0.738875 1.62 Up NM_146511 MGC:176290 IMAGE:9055941) chrX:50400250- -1.2327 -0.536355 1.62 Up 50410825_R chrX:50400250-50410825_R NudC domain containing 1, mRNA (cDNA clone -0.666065 -1.357975 1.62 Down NM_026149 MGC:37103 IMAGE:4952090) -1.88468 -1.18972 1.62 Up NM_183035 Defensin beta 34 (Defb34), mRNA -0.895925 -1.593425 1.62 Down XR_105456 Gm4419 -0.532855 -1.224565 1.62 Down NM_018764 Protocadherin 7 (Pcdh7), transcript variant 2, mRNA -1.580835 -2.27516 1.62 Down NM_028664 Ankrd45 -0.728115 -1.424645 1.62 Down NM_011569 Tektin 1 (Tekt1), mRNA chr8:24327427- -1.185255 -1.87718 1.62 Down 24332452_R chr8:24327427-24332452_R chr2:143992000- -1.12063 -0.420215 1.62 Up 143992611_F chr2:143992000-143992611_F ENSMUST00000 -0.44471 -1.13851 1.62 Down 169233 Ptch1 Echinoderm microtubule associated protein like 1, -0.42712 0.27226 1.62 Up NM_001043335 mRNA (cDNA clone IMAGE:4456782) chr19:58222540- -0.284375 -0.98034 1.62 Down 58223077_F chr19:58222540-58223077_F Tubulin polymerization promoting protein (Tppp), 0.26314 -0.429935 1.62 Down NM_182839 mRNA ENSMUST00000 Sialic acid binding Ig-like lectin 1, sialoadhesin 0.386005 -0.31299 1.62 Down 152709 (Siglec1), mRNA ENSMUST00000 Homer homolog 1 (Drosophila) (Homer1), transcript 1.388895 2.083215 1.62 Up 105261 variant L, mRNA chr17:56790296- 0.901925 1.594465 1.62 Up 56803875_F chr17:56790296-56803875_F chr9:55786058- 0.305995 1.00496 1.62 Up 55797810_F chr9:55786058-55797810_F 0.75443 1.449555 1.62 Up NM_153111 FEV (ETS oncogene family) (Fev), mRNA 0.72314 1.42353 1.62 Up NM_177371 TNF superfamily ligand TL1A (Tnfsf15) ENSMUST00000 RIKEN cDNA 4921513D23 gene, mRNA (cDNA 1.514335 0.81899 1.62 Down 099407 clone IMAGE:4947193) ENSMUST00000 2.556745 3.253505 1.62 Up 109244 Cdc20b PREDICTED: Mus musculus RIKEN cDNA 2.15413 1.46231 1.62 Down AK013908 3021401N23 gene (3021401N23Rik), mRNA Rhomboid family 1 (Drosophila), mRNA (cDNA 1.55702 2.255745 1.62 Up NM_010117 clone MGC:28292 IMAGE:4011421) 1.84411 1.15108 1.62 Down TC1695966 TC1695966 1.184575 0.490825 1.62 Down AK051746 Transcribed locus 1.253825 0.557135 1.62 Down NM_029847 Arylsulfatase K (Arsk), mRNA Protein tyrosine phosphatase, non-receptor type 21 1.574865 0.877145 1.62 Down NM_011877 (Ptpn21), mRNA RIKEN cDNA 4922505G16 gene, mRNA (cDNA 1.996135 1.297655 1.62 Down NM_001039557 clone MGC:183848 IMAGE:9087848) chr14:55433382- 5.89109 6.591485 1.62 Up 55452757_R chr14:55433382-55452757_R Zinc finger protein 114, mRNA (cDNA clone 1.794015 1.10004 1.62 Down NM_001029933 MGC:169936 IMAGE:8861331) Transcribed locus, strongly similar to XP_001480261.1 PREDICTED: hypothetical protein 1.99247 2.68723 1.62 Up AK037423 [Mus musculus] Acetyl-Coenzyme A acetyltransferase 3 (Acat3), 5.94064 6.637485 1.62 Up NM_153151 mRNA ST3 beta-galactoside alpha-2,3-sialyltransferase 1 7.10414 7.795785 1.62 Up NM_009177 (St3gal1), mRNA 5.28144 4.58471 1.62 Down NM_009644 Aryl-hydrocarbon receptor repressor (Ahrr), mRNA Cytochrome c oxidase, subunit VI a, polypeptide 2, mRNA (cDNA clone MGC:41177 0.84268 1.539735 1.62 Up NM_009943 IMAGE:1447375) chr14:67587065- 1.665315 0.97038 1.62 Down 67588705_F chr14:67587065-67588705_F Killer cell lectin-like receptor family E member 1 5.37199 4.674575 1.62 Down NM_153590 (Klre1), mRNA 3.652245 2.95266 1.62 Down NM_029497 Urb1 chrX:20555593- 3.242565 2.54274 1.62 Down 20591971_F chrX:20555593-20591971_F RIKEN cDNA 1110051M20 gene, mRNA (cDNA 3.714895 3.01526 1.62 Down NM_175123 clone MGC:113786 IMAGE:6843427) TBC1 domain family, member 16, mRNA (cDNA 3.33291 4.03251 1.62 Up NM_172443 clone MGC:67717 IMAGE:2866041) Dysbindin (dystrobrevin binding protein 1) domain 1.30913 0.60997 1.62 Down NM_028146 containing 1 (Dbndd1), mRNA 3.29933 3.9909 1.62 Up XR_035350 Gm8995 Transcription factor NF 1 mRNA, partial cds, 5.79469 5.095185 1.62 Down NM_008688 alternatively spliced 4.01379 3.314365 1.62 Down NM_146000 BUD13 homolog (yeast) (Bud13), mRNA chr17:3213918- 3.7545 3.061995 1.62 Down 3257944_F chr17:3213918-3257944_F 6.73214 6.037135 1.62 Down NM_177763 MKIAA4027 protein Epithelial cell adhesion molecule, mRNA (cDNA 2.795255 3.49098 1.62 Up NM_008532 clone MGC:11680 IMAGE:3711069) BTB and CNC homology 2 (Bach2), transcript 6.86249 6.170785 1.62 Down NM_001109661 variant 2, mRNA Holocarboxylase synthetase (biotin- [propriony- Coenzyme A-carboxylase (ATP-hydrolysing)] 3.58635 2.89423 1.62 Down NM_139145 ligase) (Hlcs), mRNA Hypothetical protein LOC574437, mRNA (cDNA 7.58814 6.893285 1.62 Down NM_001081643 clone IMAGE:3326251) SREBP cleavage activating protein, mRNA (cDNA 8.10559 7.409735 1.62 Down NM_001001144 clone IMAGE:5251383) Transmembrane protein 136, mRNA (cDNA clone 2.656525 1.963225 1.62 Down NM_001034863 MGC:170673 IMAGE:8862068) Family with sequence similarity 73, member A, mRNA (cDNA clone MGC:169953 7.08174 6.385635 1.62 Down A_55_P2052881 IMAGE:8861348) chr6:86477309- -1.88539 -2.569415 1.61 Down 86537554_R chr6:86477309-86537554_R Paired immunoglobin-like type 2 receptor alpha -0.6552 -1.34018 1.61 Down NM_153510 (Pilra), mRNA chr6:67052066- -2.160265 -1.475295 1.61 Up 67119366_F chr6:67052066-67119366_F chr6:122725638- -2.200265 -1.516935 1.61 Up 122752828_F chr6:122725638-122752828_F chr8:20020266- -1.146345 -1.83491 1.61 Down 20021248_F chr8:20020266-20021248_F -1.90285 -1.217335 1.61 Up NM_175176 4922501L14Rik Zinc finger E-box binding homeobox 2 (Zeb2), -2.360375 -1.672625 1.61 Up NM_015753 transcript variant 2, mRNA chr6:39205913- -1.791755 -1.102455 1.61 Up 39248468_F chr6:39205913-39248468_F -1.46777 -2.156185 1.61 Down NM_029048 Speedy homolog B (Drosophila) (Spdyb), mRNA -0.85536 -1.544015 1.61 Down NR_024257 4930412O13Rik chr4:135896689- -2.005465 -1.314415 1.61 Up 135918414_R chr4:135896689-135918414_R -1.260015 -0.575455 1.61 Up NM_146445 Olfactory receptor 450 (Olfr450), mRNA PREDICTED: Mus musculus similar to odorant -1.20084 -0.51028 1.61 Up XM_001472904 binding protein 2A (LOC100039446), mRNA chr3:95461528- -0.837935 -1.52281 1.61 Down 95461939_R chr3:95461528-95461939_R chr18:4415233- -1.57364 -2.25985 1.61 Down 4415995_F chr18:4415233-4415995_F Low density lipoprotein receptor-related protein 3 -1.98607 -1.299275 1.61 Up NM_001024707 (Lrp3), mRNA ENSMUST00000 -1.59095 -0.899475 1.61 Up 138535 ENSMUST00000138535 -1.26764 -1.955395 1.61 Down AK161453 Transcribed locus -1.694415 -1.00295 1.61 Up NM_146791 Olfactory receptor 1248 (Olfr1248), mRNA chr16:40463859- -1.76695 -1.07636 1.61 Up 40464481_R chr16:40463859-40464481_R -1.937835 -1.24858 1.61 Up NM_001177438 Aldh3b2 chr1:183811267- -1.589795 -0.90078 1.61 Up 183816309_F chr1:183811267-183816309_F chr10:62347876- -1.702115 -1.018065 1.61 Up 62374346_R chr10:62347876-62374346_R Inter alpha-trypsin inhibitor, heavy chain 4, mRNA -0.8943 -1.58106 1.61 Down NM_018746 (cDNA clone MGC:25281 IMAGE:4211735) chr7:31709550- -0.620455 -1.305065 1.61 Down 31723025_F chr7:31709550-31723025_F chr18:47327300- -1.360795 -2.050875 1.61 Down 47333819_R chr18:47327300-47333819_R RIKEN cDNA 1700001C19 gene, mRNA (cDNA -1.07971 -0.390065 1.61 Up NM_029296 clone MGC:40720 IMAGE:5124927) chr9:78107225- -1.42373 -2.11031 1.61 Down 78118850_F chr9:78107225-78118850_F -1.555265 -0.864845 1.61 Up NM_001126490 Isthmin 1 homolog (zebrafish) (Ism1), mRNA -0.766595 -1.45337 1.61 Down NM_010628 Kinesin family member 9 (Kif9), mRNA chr5:53931541- -1.39659 -0.70645 1.61 Up 53945241_F chr5:53931541-53945241_F Enoyl Coenzyme A hydratase domain containing 3 -2.064995 -1.3779 1.61 Up NM_024208 (Echdc3), mRNA Cysteine dioxygenase 1, cytosolic, mRNA (cDNA -0.558595 -1.242815 1.61 Down NM_033037 clone MGC:18800 IMAGE:4194939) chrX:50087925- -1.40005 -0.716115 1.61 Up 50101700_F chrX:50087925-50101700_F chr11:102878974 -1.238055 -1.921575 1.61 Down -102888924_R chr11:102878974-102888924_R -1.732545 -1.048135 1.61 Up NM_011684 Vomeronasal 1 receptor, A2 (V1ra2), mRNA -0.282835 -0.972535 1.61 Down A_55_P2179069 A_55_P2179069 chr1:58443698- -1.369595 -0.67876 1.61 Up 58449898_F chr1:58443698-58449898_F chr15:102026122 -0.553495 0.135125 1.61 Up -102033725_F chr15:102026122-102033725_F chr6:13801450- -0.41565 -1.10516 1.61 Down 13853450_F chr6:13801450-13853450_F -0.21165 0.47469 1.61 Up NM_007441 Aristaless-like homeobox 3 (Alx3), mRNA 0.583005 1.269445 1.61 Up CB840983 Transcribed locus 0.224425 0.911495 1.61 Up NM_146877 Olfactory receptor 1395 (Olfr1395), mRNA chr5:125078875- 0.5364 1.2225 1.61 Up 125098525_R chr5:125078875-125098525_R 1.08256 1.773835 1.61 Up NM_011770 IKAROS family zinc finger 2 (Ikzf2), mRNA chr2:151992806- 6.08929 5.4 1.61 Down 152025456_F chr2:151992806-152025456_F Transmembrane protein 2 (Tmem2), transcript 3.318415 4.008855 1.61 Up NM_031997 variant 1, mRNA ENSMUST00000 1.38925 0.702515 1.61 Down 026094 Headcase homolog (Drosophila) (Heca), mRNA chr7:88131123- 2.437385 1.751045 1.61 Down 88136898_R chr7:88131123-88136898_R 3.93159 3.244845 1.61 Down NR_027829 Gm10638 Deleted in lymphocytic leukemia, 7, mRNA (cDNA 1.095475 0.41253 1.61 Down NM_173419 clone MGC:47306 IMAGE:4235022) chr18:79286360- 2.89102 2.206915 1.61 Down 79304510_R chr18:79286360-79304510_R 1.43601 0.75201 1.61 Down NM_016769 MAD homolog 3 (Drosophila) (Smad3), mRNA ENSMUST00000 0.474515 -0.214415 1.61 Down 150694 Transcribed locus Protein phosphatase 2C, magnesium dependent, catalytic subunit, mRNA (cDNA clone 2.09556 1.40616 1.61 Down NM_001098230 MGC:170617 IMAGE:8862012) chr11:55315017- 1.74162 1.05644 1.61 Down 55322092_R chr11:55315017-55322092_R RIKEN cDNA A130022J15 gene (A130022J15Rik), 3.57583 2.88488 1.61 Down NM_175313 mRNA Eukaryotic translation initiation factor 4 gamma, 3, 2.35872 1.67473 1.61 Down NM_172703 mRNA (cDNA clone IMAGE:5321197) chr1:63163023- 0.947425 0.257465 1.61 Down 63180223_F chr1:63163023-63180223_F Dual specificity phosphatase 1, mRNA (cDNA clone 3.932665 3.24166 1.61 Down NM_013642 MGC:6265 IMAGE:3589849) MAS-related GPR, member G, mRNA (cDNA clone 1.53435 0.844665 1.61 Down A_55_P2180861 MGC:117497 IMAGE:30522259) THAP domain containing, apoptosis associated protein 1, mRNA (cDNA clone MGC:47985 2.78839 2.10364 1.61 Down NM_199042 IMAGE:5118383) 3.978865 3.287715 1.61 Down NM_133358 Zinc finger protein 617 (Zfp617), mRNA chr3:19211659- 2.37105 1.68761 1.61 Down 19213735_F chr3:19211659-19213735_F Methyltransferase like 6, mRNA (cDNA clone 5.45069 4.759215 1.61 Down NM_025907 MGC:40619 IMAGE:5400506) Ubiquitin specific peptidase 9, X chromosome 4.52784 3.84045 1.61 Down NM_009481 (Usp9x), mRNA Peroxisomal biogenesis factor 11a, mRNA (cDNA 4.64839 3.96096 1.61 Down NM_011068 clone IMAGE:1246184) 8.48469 7.800985 1.61 Down NM_198862 MKIAA1366 protein 3.322115 2.63696 1.61 Down NM_026679 D14Ertd449e Oculocerebrorenal syndrome of Lowe, mRNA 6.29659 5.611835 1.61 Down NM_177215 (cDNA clone MGC:93022 IMAGE:30533468) 6.99319 6.305185 1.61 Down NM_207687 Espin (Espn), transcript variant 6, mRNA Sprouty-related, EVH1 domain containing 2, mRNA 3.92285 3.236295 1.61 Down NM_033523 (cDNA clone IMAGE:4946146) MORN repeat containing 3, mRNA (cDNA clone 0.17012 0.858965 1.61 Up NM_029112 MGC:28963 IMAGE:4458628) Brain cDNA, clone MNCb-1275, similar to Mus musculus F-box protein containing leucine repeats 6 4.16336 3.479635 1.61 Down NM_013909 (Fbl6), mRNA TSPY-like 4, mRNA (cDNA clone MGC:38849 3.92697 3.240825 1.61 Down NM_030203 IMAGE:5361000) 4.73769 4.05285 1.61 Down NM_001162906 2410089E03Rik 6.00184 5.317285 1.61 Down NM_001177884 Whsc1 N-6 adenine-specific DNA methyltransferase 2 6.59604 5.909085 1.61 Down NM_026526 (putative) (N6amt2), mRNA RanBP-type and C3HC4-type zinc finger containing ENSMUST00000 1, mRNA (cDNA clone MGC:19065 9.70219 10.393185 1.61 Up 082396 IMAGE:4192310) 8.71749 8.032435 1.61 Down NM_028385 CDNA clone IMAGE:30544637 Adaptor protein complex AP-2, alpha 1 subunit, mRNA (cDNA clone MGC:25419 6.44984 5.766285 1.61 Down NM_007458 IMAGE:4481643) ENSMUST00000 Ubiquitin specific peptidase 21, mRNA (cDNA 5.22974 4.541135 1.61 Down 051049 clone MGC:18739 IMAGE:3985792) Oculocerebrorenal syndrome of Lowe, mRNA 11.94264 11.253785 1.61 Down NAP068489-1 (cDNA clone MGC:93022 IMAGE:30533468) -0.32439 -1.00069 1.6 Down NM_053221 Vomeronasal 1 receptor, A6 (V1ra6), mRNA PREDICTED: Mus musculus hypothetical protein -1.35529 -0.680715 1.6 Up BB203186 LOC100043778 (LOC100043778), mRNA -0.59527 -1.273835 1.6 Down NM_153166 Copine V (Cpne5), mRNA Transcribed locus, strongly similar to NP_038839.2 -0.834545 -1.509405 1.6 Down AK077156 dynein, axonemal, heavy chain 8 [Mus musculus] chr10:18047851- -1.893815 -2.57275 1.6 Down 18049641_R chr10:18047851-18049641_R -0.98574 -1.665615 1.6 Down NM_174998 NVP-2 mRNA for neural visinin-like protein 2 -1.03328 -1.708935 1.6 Down chr8:70623390- chr8:70623390-70645212_R 70645212_R -1.002515 -1.67704 1.6 Down A_55_P1995133 A_55_P1995133 chr6:5311375- -1.610085 -0.929125 1.6 Up 5328075_R chr6:5311375-5328075_R -1.09368 -0.41772 1.6 Up NM_054085 Alpha-kinase 3 (Alpk3), mRNA -1.66219 -0.981465 1.6 Up NM_001195128 Gm5294 chr2:176583825- -0.677885 -1.359735 1.6 Down 176714400_F chr2:176583825-176714400_F RIKEN cDNA C330005M16 gene, mRNA (cDNA -1.515435 -0.83858 1.6 Up NM_175319 clone MGC:169932 IMAGE:8861327) chr1:71730016- -1.69151 -1.013335 1.6 Up 71740391_R chr1:71730016-71740391_R -0.989075 -0.314765 1.6 Up XR_105930 1010001N08Rik -0.656065 -1.33845 1.6 Down NM_178874 MKIAA0481 protein Selection and upkeep of intraepithelial T cells 3 -1.139805 -1.815075 1.6 Down NM_177578 (Skint3), transcript variant 1, mRNA chr14:72437199- -1.295355 -1.972625 1.6 Down 72437307_F chr14:72437199-72437307_F Phytanoyl-CoA hydroxylase interacting protein -0.944955 -1.625625 1.6 Down NM_145981 (Phyhip), mRNA Phytanoyl-CoA dioxygenase domain containing 1, ENSMUST00000 mRNA (cDNA clone MGC:178922 -0.4146 -1.093945 1.6 Down 122858 IMAGE:9053914) chr11:22500336- -1.784855 -1.11117 1.6 Up 22520995_R chr11:22500336-22520995_R Guanine nucleotide binding protein (G protein), gamma 7, mRNA (cDNA clone MGC:31559 -0.327935 -1.004765 1.6 Down NM_001038655 IMAGE:4503666) -0.93919 -1.61384 1.6 Down AK087464 CDNA clone IMAGE:5365341 chr6:34548561- -1.890695 -1.212735 1.6 Up 34612216_F chr6:34548561-34612216_F -1.073635 -1.750375 1.6 Down NM_145216 RAS-like, family 10, member A (Rasl10a), mRNA -0.73533 -0.05926 1.6 Up A_55_P2124331 Vomeronasal 1 receptor, E7 (V1re7), mRNA chr6:52046805- -0.5258 0.151745 1.6 Up 52072744_R chr6:52046805-52072744_R ENSMUST00000 Calcium release-activated calcium channel 3 (Orai3 -0.73766 -1.418375 1.6 Down 103162 gene) Gene model 1679, (NCBI), mRNA (cDNA clone -0.996735 -0.31944 1.6 Up NM_001033459 MGC:182195 IMAGE:9056089) chr9:56646768- -1.47099 -0.791035 1.6 Up 56649068_R chr9:56646768-56649068_R -0.51292 0.16651 1.6 Up NM_201530 Sycp3 like Y-linked (Sly), mRNA chr2:155269145- -0.186185 -0.86792 1.6 Down 155303251_F chr2:155269145-155303251_F ENSMUST00000 Major facilitator superfamily domain containing 5 -0.043665 0.631655 1.6 Up 056619 (Mfsd5), mRNA RAN guanine nucleotide release factor, mRNA 2.949305 2.26758 1.6 Down NM_021329 (cDNA clone MGC:46834 IMAGE:5344659) FERM, RhoGEF and pleckstrin domain protein 2 0.1707 -0.5081 1.6 Down AK086699 (Farp2), mRNA chr7:77323753- 0.632335 1.31027 1.6 Up 77482708_R chr7:77323753-77482708_R Purinergic receptor P2X, ligand-gated ion channel, 3 0.408015 1.089525 1.6 Up NM_145526 (P2rx3), mRNA chr4:54851872- 0.780565 1.458 1.6 Up 54866706_R chr4:54851872-54866706_R Basic, immunoglobulin-like variable motif- 0.60204 -0.074795 1.6 Down NM_144558 containing protein (Bivm) B-cell leukemia/lymphoma 2 related protein A1a, mRNA (cDNA clone MGC:41220 4.74249 4.0669 1.6 Down NM_001128601 IMAGE:1226745) 1.244795 0.569585 1.6 Down AI593498 Transcribed locus Leukocyte tyrosine kinase (Ltk), transcript variant 1, 1.028505 0.34948 1.6 Down NM_203345 mRNA 5.38714 4.704635 1.6 Down NM_001033669 Tripartite motif-containing 16 (Trim16), mRNA 3.62134 2.94388 1.6 Down AK163891 Transcribed locus Src homology 2 domain-containing transforming protein E, mRNA (cDNA clone MGC:130415 1.224205 0.547625 1.6 Down NM_172530 IMAGE:40058814) Cysteine-rich repeat-containing protein CRIM1 1.77975 2.454265 1.6 Up NM_015800 (Crim1) DNA segment, Chr 16, Brigham & Womens Genetics 1494 expressed, mRNA (cDNA clone 1.438305 2.11673 1.6 Up NM_177473 IMAGE:3470198) ELK1, member of ETS oncogene family (Elk1), 1.16983 0.490525 1.6 Down NM_007922 mRNA ENSMUST00000 0.5813 1.256105 1.6 Up 103590 TSPY-like 3 (Tspyl3), mRNA ENSMUST00000 1.54267 2.218475 1.6 Up 077110 ENSMUST00000077110 chr17:33995525- 0.89137 1.566235 1.6 Up 34028025_F chr17:33995525-34028025_F chr12:33808493- 2.673205 1.99235 1.6 Down 33829143_F chr12:33808493-33829143_F Beta-1,4-N-acetyl-galactosaminyl transferase 3, mRNA (cDNA clone MGC:157481 3.070225 3.749075 1.6 Up NAP027978-1 IMAGE:40060840) Arsenic (+3 oxidation state) methyltransferase 4.267125 3.589995 1.6 Down NM_020577 (As3mt), mRNA Acetyl-Coenzyme A acetyltransferase 2, mRNA 3.5704 4.25199 1.6 Up NM_009338 (cDNA clone MGC:21591 IMAGE:4500929) chr7:99879368- 1.994685 1.31591 1.6 Down 99889978_R chr7:99879368-99889978_R chr14:103751075 2.873085 2.196665 1.6 Down -103769725_F chr14:103751075-103769725_F RING CCCH (C3H) domains 1, mRNA (cDNA 3.182395 2.50571 1.6 Down NM_001024952 clone MGC:170289 IMAGE:8861684) ENSMUST00000 Cation channel, sperm associated 2 (Catsper2), 0.47653 -0.20512 1.6 Down 099478 mRNA Solute carrier family 4 (anion exchanger), member 4, 1.97802 1.300715 1.6 Down NM_018760 mRNA (cDNA clone IMAGE:4973987) Ubiquitin specific peptidase 8, mRNA (cDNA clone 1.712725 1.031745 1.6 Down NM_019729 IMAGE:5041516) 5.85709 6.534435 1.6 Up NM_026376 Plexin D1, mRNA (cDNA clone IMAGE:4219417) 5.35684 4.682935 1.6 Down NR_028432 2210013O21Rik Membrane-spanning 4-domains, subfamily A, member 4B, mRNA (cDNA clone MGC:41078 4.50301 5.183635 1.6 Up NM_021718 IMAGE:1248222) AlkB, alkylation repair homolog 1 (E. coli) 4.29856 3.623835 1.6 Down NM_001102565 (Alkbh1), mRNA Solute carrier family 16 (monocarboxylic acid transporters), member 11 (Slc16a11), transcript 2.61038 3.28555 1.6 Up NM_153081 variant 3, mRNA RIKEN cDNA B630019K06 gene, mRNA (cDNA 1.750285 1.068675 1.6 Down NM_175327 clone MGC:67565 IMAGE:6403722) 3.43101 2.757105 1.6 Down NM_145582 ATP binding domain 3 (Atpbd3), mRNA Anterior pharynx defective 1b homolog (C. elegans), mRNA (cDNA clone MGC:90603 2.794585 2.11233 1.6 Down NM_177583 IMAGE:6853991) 2.031235 1.352345 1.6 Down NM_010667 Hair keratin, mHb6 Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 3.653295 2.97485 1.6 Down NM_145991 (Cdc73), mRNA Transmembrane protein 20, mRNA (cDNA clone 5.15499 4.48095 1.6 Down NM_175507 MGC:169287 IMAGE:8860682) 2.73117 2.05535 1.6 Down XM_356261 Gm5165 4.77774 4.101775 1.6 Down AK051948 Transcribed locus 5.87674 6.554235 1.6 Up NM_145500 Ubiquitin domain containing 1 (Ubtd1), mRNA 8.96324 8.286685 1.6 Down NR_033146 LOC100316870 2.13905 2.81395 1.6 Up NM_010430 Hypermethylated in cancer 1 (Hic1) Profilin 2, mRNA (cDNA clone MGC:35930 5.54864 4.869835 1.6 Down NM_019410 IMAGE:5059568) CDNA fis, clone TRACH2016551, highly similar to 2.58788 1.907135 1.6 Down NM_011794 Mus musculus bisphosphate 3-nucleotidase mRNA Zinc finger, CCHC domain containing 3, mRNA 2.677525 2.00027 1.6 Down NM_175126 (cDNA clone MGC:67159 IMAGE:6412435) PREDICTED: Mus musculus predicted gene, 1.434855 0.75442 1.6 Down AK141442 EG664949 (EG664949), misc RNA S100 calcium binding protein A11 (calgizzarin) 6.20304 5.528535 1.6 Down NM_016740 (S100a11), mRNA Glutathione S-transferase, theta 1, mRNA (cDNA 6.41414 7.093285 1.6 Up NM_008185 clone MGC:19075 IMAGE:4193816) 6.50839 5.831385 1.6 Down NM_019507 T-box 21 (Tbx21), mRNA Basic leucine zipper and W2 domains 1, mRNA 4.53894 3.86362 1.6 Down NM_025824 (cDNA clone MGC:25505 IMAGE:4910833) Stromal interaction molecule 2, mRNA (cDNA clone 3.578745 2.898515 1.6 Down NM_001081103 MGC:178557 IMAGE:9053549) Transducer of ERBB2, 2, mRNA (cDNA clone 6.25409 5.580135 1.6 Down NM_020507 MGC:18667 IMAGE:4194136) 5.29854 4.623335 1.6 Down NM_001162906 2410089E03Rik chr17:85418489- -1.26872 -1.94136 1.59 Down 85427364_R chr17:85418489-85427364_R chr9:100977450- -1.7095 -1.042165 1.59 Up 100989325_R chr9:100977450-100989325_R chr6:83841733- -1.294435 -0.6261 1.59 Up 83842297_F chr6:83841733-83842297_F Aurora kinase C (Aurkc), transcript variant 3, -1.34093 -2.009475 1.59 Down NM_001080966 mRNA -1.22185 -1.88869 1.59 Down BU848224 Transcribed locus Family with sequence similarity 38, member B, mRNA (cDNA clone MGC:182702 -1.565345 -2.234855 1.59 Down NM_001039485 IMAGE:9056596) chr1:58440355- -1.273435 -1.940105 1.59 Down 58449627_R chr1:58440355-58449627_R chr14:67585234- -1.104415 -1.77787 1.59 Down 67596823_R chr14:67585234-67596823_R Tripartite motif-containing 42, mRNA (cDNA clone -1.63884 -2.31225 1.59 Down NM_030219 IMAGE:40059460) Aldehyde dehydrogenase family 7, member A1 -1.64131 -0.9695 1.59 Up NM_138600 (Aldh7a1), transcript variant 1, mRNA chr8:87513394- -0.708245 -1.37624 1.59 Down 87514107_R chr8:87513394-87514107_R chr13:23519843- -0.73467 -1.40515 1.59 Down 23522887_R chr13:23519843-23522887_R Otopetrin 3, mRNA (cDNA clone MGC:183714 -0.618175 -1.286865 1.59 Down NM_027132 IMAGE:9087714) chr7:119735208- -1.837195 -2.503465 1.59 Down 119822808_R chr7:119735208-119822808_R -1.59201 -0.92383 1.59 Up NM_001081254 Predicted gene, EG545136 (EG545136), mRNA chr5:92548501- -1.612435 -2.277775 1.59 Down 92566401_F chr5:92548501-92566401_F -1.29462 -0.625485 1.59 Up NM_176913 Putative membrane-bound dipeptidase-2 -1.287705 -1.953885 1.59 Down NM_026864 RAS-like, family 11, member A (Rasl11a), mRNA chr13:98571741- -1.440165 -0.77294 1.59 Up 98603323_F chr13:98571741-98603323_F -1.115455 -0.445415 1.59 Up A_55_P2026034 Melanocortin 5 receptor (Mc5r), mRNA chr10:93975406- -0.372385 -1.038065 1.59 Down 93977476_R chr10:93975406-93977476_R ENSMUST00000 Tripartite motif family-like 1, mRNA (cDNA clone -1.158335 -0.49187 1.59 Up 103678 MGC:179102 IMAGE:9054094) Kinesin family member 14, mRNA (cDNA clone -1.846095 -1.17993 1.59 Up NM_001081258 MGC:189899 IMAGE:9007399) -1.56681 -0.89461 1.59 Up A_55_P2015555 Inhibitory PAS domain protein (Ipas) -1.549355 -0.878845 1.59 Up NM_013905 Hairy-related transcription factor 3 (Hrt3) chr1:183783306- -1.483295 -0.813495 1.59 Up 183834531_R chr1:183783306-183834531_R Torsin A interacting protein 2, mRNA (cDNA clone -0.8667 -1.538905 1.59 Down NM_172843 MGC:76434 IMAGE:30099444) chr4:128727332- -1.45479 -0.788685 1.59 Up 128735227_F chr4:128727332-128735227_F chr3:40966969- -1.51887 -0.847505 1.59 Up 40976585_R chr3:40966969-40976585_R chr14:79304650- -0.985745 -0.320075 1.59 Up 79345152_F chr14:79304650-79345152_F Dual endothelin 1/angiotensin II receptor 1 homolog ENSMUST00000 (rat), mRNA (cDNA clone MGC:176175 -1.0378 -1.70931 1.59 Down 092131 IMAGE:9055826) ENSMUST00000 -0.317835 -0.98592 1.59 Down 023605 2-5 oligoadenylate synthetase 3 (Oas3), mRNA -1.14119 -0.47447 1.59 Up AK014901 Transcribed locus -1.636395 -0.968905 1.59 Up NM_001166842 Vmn1r168 chr5:88995039- -0.84881 -0.18032 1.59 Up 89009064_R chr5:88995039-89009064_R chr8:44232164- -0.97374 -0.30852 1.59 Up 44267061_R chr8:44232164-44267061_R RIKEN cDNA 9930032O22 gene, mRNA (cDNA -1.01603 -0.34331 1.59 Up NM_177162 clone MGC:148215 IMAGE:40107184) 0.51534 1.179835 1.59 Up NM_001161362 Ppp2r3a 0.37677 1.04374 1.59 Up NM_030206 Cytoglobin (Cygb), mRNA chr11:117835849 0.234555 -0.43559 1.59 Down -117842574_F chr11:117835849-117842574_F chr15:102947390 0.226355 -0.441095 1.59 Down -102971082_R chr15:102947390-102971082_R 0.315175 -0.352615 1.59 Down NM_027559 Wdr96 Ribosomal protein L36A, mRNA (cDNA clone 0.200475 0.872885 1.59 Up A_55_P2102833 MGC:41090 IMAGE:1383212) 1.072335 1.73969 1.59 Up NM_001161536 Islr2 chr4:11899775- 0.31905 -0.351205 1.59 Down 11931875_F chr4:11899775-11931875_F chr8:34646787- 1.777555 1.11094 1.59 Down 34680312_F chr8:34646787-34680312_F Trans-acting transcription factor 3, mRNA (cDNA 1.001575 0.33207 1.59 Down NM_001018042 clone IMAGE:5323205) chr16:31321192- 1.666835 2.335585 1.59 Up 31333486_F chr16:31321192-31333486_F ENSMUST00000 Melanin-concentrating hormone receptor 1 (Mchr1), 0.44742 -0.21845 1.59 Down 091609 mRNA Predicted gene, OTTMUSG00000010673 2.40212 1.729155 1.59 Down NM_001014397 (OTTMUSG00000010673), mRNA Zinc finger and BTB domain containing 4 (Zbtb4), 2.860825 2.194945 1.59 Down NM_029348 mRNA 2.8405 3.50973 1.59 Up NM_010094 Left right determination factor 1 (Lefty1), mRNA Brain expressed X-linked 2, mRNA (cDNA clone 0.99996 0.32817 1.59 Down NM_009749 MGC:41182 IMAGE:5058536) chrX:130742592- 1.495035 0.82711 1.59 Down 130744509_R chrX:130742592-130744509_R 4.026905 3.35625 1.59 Down NM_025329 Tctex1 domain containing 2 (Tctex1d2), mRNA RIKEN cDNA A130010J15 gene, mRNA (cDNA 1.905995 1.24095 1.59 Down NM_181048 clone MGC:68405 IMAGE:4527064) 1.857645 1.19152 1.59 Down NM_001163996 Zfp605 chr19:29582018- 0.709435 1.376655 1.59 Up 29596693_R chr19:29582018-29596693_R 1.760665 2.431045 1.59 Up NM_008240 Forkhead Box j1 (Foxj1) Lymphocyte antigen 6 complex, locus G5B 2.13233 2.79982 1.59 Up NM_148939 (Ly6g5b), mRNA 3.005695 2.334725 1.59 Down NM_001008501 Zinc finger protein 760 (Zfp760), mRNA Tubulin tyrosine ligase-like family, member 3 2.82638 2.155695 1.59 Down NM_001142732 (Ttll3), transcript variant 1, mRNA 2.6989 2.029845 1.59 Down NM_001198823 App chr13:24615451- 3.71533 3.05042 1.59 Down 24615973_F chr13:24615451-24615973_F chr5:96591892- 7.22929 7.898885 1.59 Up 96606467_F chr5:96591892-96606467_F Sideroflexin 2, mRNA (cDNA clone MGC:30418 3.47982 2.81224 1.59 Down NM_053196 IMAGE:5043343) RIKEN cDNA A530094I17 gene, mRNA (cDNA 2.45706 1.78668 1.59 Down NM_001007575 clone IMAGE:4949856) CSA-conditional, T cell activation-dependent protein, mRNA (cDNA clone MGC:151394 4.36967 3.70346 1.59 Down NM_030137 IMAGE:40126336) Colony stimulating factor 1 (macrophage), mRNA 1.625525 0.95711 1.59 Down NM_001113530 (cDNA clone IMAGE:5342906) Ornithine decarboxylase, structural 1, mRNA 5.76184 6.430335 1.59 Up NM_013614 (cDNA clone MGC:25367 IMAGE:2645291) 3.02308 2.35458 1.59 Down NM_001164220 Trim13 Polycomb group ring finger 1, mRNA (cDNA clone 3.78803 3.123245 1.59 Down NM_197992 MGC:41745 IMAGE:1380201) Rho GDP dissociation inhibitor (GDI) gamma, 4.18336 3.511255 1.59 Down NM_008113 mRNA (cDNA clone MGC:5923 IMAGE:3490167) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4, mRNA (cDNA 3.382035 2.714215 1.59 Down NM_019804 clone MGC:35921 IMAGE:5026168) Small EDRK-rich factor 1, mRNA (cDNA clone 6.92964 6.262135 1.59 Down NM_011353 MGC:41144 IMAGE:1510984) Zinc finger protein 672, mRNA (cDNA clone 5.52444 4.854235 1.59 Down NM_178761 MGC:27920 IMAGE:3582315) Apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3, mRNA (cDNA clone MGC:7002 6.45764 5.791785 1.59 Down NM_030255 IMAGE:3155422) Acyl-CoA thioesterase 1, mRNA (cDNA clone 3.74765 3.080445 1.59 Down NM_012006 MGC:40635 IMAGE:5100478) 6.55589 5.885085 1.59 Down NM_207203 CDNA sequence BC068157 (BC068157), mRNA 4.74294 4.078385 1.59 Down NM_025776 RNA binding motif protein 22 (Rbm22), mRNA 5.11709 4.448605 1.59 Down NM_153793 RELT-like 2 (Rell2), mRNA Spire homolog 1 (Drosophila), mRNA (cDNA clone 2.324985 1.6541 1.59 Down NM_194355 MGC:106458 IMAGE:30535423) Tudor domain containing 3, mRNA (cDNA clone 5.30484 4.63266 1.59 Down BC005670 MGC:11761 IMAGE:3153274) 3.256055 2.587995 1.59 Down NM_145142 Carbohydrate sulfotransferase 10 (Chst10), mRNA BEN domain containing 5, mRNA (cDNA clone 6.44104 5.768235 1.59 Down NM_026279 IMAGE:4952843) RIKEN cDNA C130079G13 gene 1.191425 0.519415 1.59 Down A_55_P2058613 (C130079G13Rik), mRNA ENSMUST00000 4.382375 3.714505 1.59 Down 048349 Ralgapa2 B and T lymphocyte associated (Btla), transcript 5.93819 5.269485 1.59 Down NM_001037719 variant 1, mRNA 6.27634 5.607235 1.59 Down A_55_P2030702 Gene model 1527, (NCBI) (Gm1527), mRNA 5.10349 4.436645 1.59 Down TUG1 TUG1 Tubulin-specific chaperone C, mRNA (cDNA clone 6.91689 6.251985 1.59 Down NM_178385 MGC:28692 IMAGE:4240883) -2.08369 -1.42338 1.58 Up NM_146843 Olfactory receptor 1097 (Olfr1097), mRNA -1.158875 -0.499885 1.58 Up AK043165 Transcribed locus -0.87619 -1.53771 1.58 Down AK147582 Transcribed locus PREDICTED: Mus musculus RIKEN cDNA -1.546205 -0.881845 1.58 Up A_55_P2002460 4932422M17 gene (4932422M17Rik), mRNA ChaC, cation transport regulator homolog 2 (E. coli), mRNA (cDNA clone MGC:35645 -1.679985 -2.33596 1.58 Down A_55_P2065572 IMAGE:3967723) -1.089855 -1.74807 1.58 Down NM_001127686 Predicted gene, EG436003 (EG436003), mRNA -1.25502 -0.595795 1.58 Up AK015390 Transcribed locus -1.00117 -0.34469 1.58 Up NM_011642 P73 alpha protein (P73 gene) -1.35367 -2.01784 1.58 Down NM_001162945 Mtx3 chr18:55040319- -1.56585 -2.222585 1.58 Down 55040708_R chr18:55040319-55040708_R chrX:11671167- -1.261015 -1.92049 1.58 Down 11700242_F chrX:11671167-11700242_F Lipoprotein lipase, mRNA (cDNA clone MGC:5666 -1.710985 -1.052935 1.58 Up NM_008509 IMAGE:3584788) ENSMUST00000 RIKEN cDNA 0610037L13 gene (0610037L13Rik), -1.557885 -0.901405 1.58 Up 132417 mRNA -2.25279 -1.595635 1.58 Up NR_027879 4930583K01Rik chr9:57959595- -0.82995 -1.49375 1.58 Down 57966629_R chr9:57959595-57966629_R ENSMUST00000 -1.607255 -0.94382 1.58 Up 110825 Nudt1 -1.54218 -2.200755 1.58 Down NM_001204912 2410017P09Rik -1.249975 -0.58815 1.58 Up AK030052 Transcribed locus -1.51464 -0.856025 1.58 Up A_55_P2071906 A_55_P2071906 -2.077645 -1.414255 1.58 Up NM_146929 Olfactory receptor 807 (Olfr807), mRNA -1.166065 -1.822185 1.58 Down NAP063229-1 Ring finger protein 181 (Rnf181), mRNA Family with sequence similarity 55, member C, mRNA (cDNA clone MGC:183882 -0.48374 -1.14388 1.58 Down NM_001134457 IMAGE:9087882) chr17:6426800- -0.90508 -1.563205 1.58 Down 6528950_R chr17:6426800-6528950_R Olfactory receptor 312, mRNA (cDNA clone -0.82894 -0.16601 1.58 Up NM_001011819 MGC:129174 IMAGE:40040766) chr3:26975624- -1.2178 -0.56139 1.58 Up 26988699_R chr3:26975624-26988699_R chr9:58301467- -1.57776 -0.920715 1.58 Up 58323783_R chr9:58301467-58323783_R chr1:163508244- -1.32893 -1.9903 1.58 Down 163586072_R chr1:163508244-163586072_R chr2:119412770- -1.126015 -1.788365 1.58 Down 119435110_R chr2:119412770-119435110_R -0.640605 -1.30303 1.58 Down NM_001012309 Coiled-coil domain containing 55 (Ccdc55), mRNA -1.62511 -0.964305 1.58 Up NR_033550 Gm10248 chr11:116562925 -1.42512 -0.768765 1.58 Up -116574575_F chr11:116562925-116574575_F chr8:94841965- -1.16184 -0.50114 1.58 Up 94881130_F chr8:94841965-94881130_F Mucin-like protocadherin (Mupcdh), transcript -0.754 -0.090725 1.58 Up NM_028069 variant 2, mRNA chr13:44217172- -0.75921 -0.102805 1.58 Up 44224947_R chr13:44217172-44224947_R chr13:5506700- -1.2667 -0.608425 1.58 Up 5519000_F chr13:5506700-5519000_F chr6:47928244- -1.687455 -1.024735 1.58 Up 47928681_R chr6:47928244-47928681_R chr17:32075308- -0.83459 -0.177525 1.58 Up 32075792_R chr17:32075308-32075792_R chr4:114627748- -0.15252 -0.814605 1.58 Down 114632898_F chr4:114627748-114632898_F -1.16703 -0.50312 1.58 Up NM_001039167 Hexaribonucleotide binding protein 3 (Hrnbp3) chr1:134167181- -1.306885 -0.6469 1.58 Up 134181386_F chr1:134167181-134181386_F -1.15024 -0.48586 1.58 Up AK031662 AK031662 -0.24558 0.4101 1.58 Up NM_001011519 Olfactory receptor 1148 (Olfr1148), mRNA chr2:143988645- 0.302075 0.96413 1.58 Up 143993945_R chr2:143988645-143993945_R Camello-like 4, mRNA (cDNA clone MGC:28664 0.49731 1.154695 1.58 Up NM_023455 IMAGE:4236543) Troponin I, skeletal, slow 1, mRNA (cDNA clone 0.41013 1.06597 1.58 Up NM_021467 MGC:35867 IMAGE:4949804) Zinc finger protein 708 (Zfp708), transcript variant 0.312055 -0.351375 1.58 Down NM_001012325 1, mRNA chr9:118291593- 0.461355 1.1196 1.58 Up 118324230_R chr9:118291593-118324230_R chr3:48896525- 0.271475 -0.38814 1.58 Down 48994125_F chr3:48896525-48994125_F Regulatory factor X, 3 (influences HLA class II expression), mRNA (cDNA clone MGC:27565 0.787885 0.12676 1.58 Down NM_011265 IMAGE:4483833) Anti-Mullerian hormone type 2 receptor (Amhr2), 0.206725 0.86279 1.58 Up NM_144547 mRNA TBC1 domain family, member 14 (Tbc1d14), 0.519775 -0.13667 1.58 Down NM_001113362 transcript variant 2, mRNA Lactalbumin, alpha, mRNA (cDNA clone 1.76039 1.104175 1.58 Down NM_010679 MGC:11989 IMAGE:3601746) chr8:34646787- 2.665245 2.00592 1.58 Down 34680312_F chr8:34646787-34680312_F 3.876175 4.54023 1.58 Up NM_001195437 Gm590 Huntingtin interacting protein 1 related, mRNA 3.26101 3.921815 1.58 Up NM_145070 (cDNA clone IMAGE:5043355) RIKEN cDNA 9030617O03 gene (9030617O03Rik), 3.69491 4.35814 1.58 Up NM_145448 mRNA PREDICTED: Mus musculus predicted gene, 1.12991 0.47402 1.58 Down BC042778 EG625237 (EG625237), mRNA Zinc finger, C4H2 domain containing, mRNA 2.729085 2.066285 1.58 Down NM_001003916 (cDNA clone MGC:155627 IMAGE:8734060) chr4:123155515- 1.64951 0.99376 1.58 Down 123361565_R chr4:123155515-123361565_R Guanine nucleotide binding protein (G protein), beta 5, mRNA (cDNA clone MGC:28984 3.23314 2.575015 1.58 Down NM_010313 IMAGE:4506201) 6.22414 5.564285 1.58 Down NM_054048 REST corepressor 2 (Rcor2), mRNA Membrane-associated ring finger (C3HC4) 5 1.780075 1.118195 1.58 Down NM_027314 (March5), mRNA chr8:110196655- 2.227885 2.887545 1.58 Up 110390197_F chr8:110196655-110390197_F 4.84679 5.508035 1.58 Up NM_023270 E3 ubiquitin ligase (Greul1) 4.10417 3.444135 1.58 Down NM_022409 Zinc finger protein 296 (Zfp296), mRNA chr14:55433382- 6.96819 7.624635 1.58 Up 55452757_R chr14:55433382-55452757_R Insulin receptor substrate 2, mRNA (cDNA clone 7.20489 6.549085 1.58 Down NM_001081212 MGC:182676 IMAGE:9056570) Transcription factor AP-2, alpha, mRNA (cDNA 2.583915 1.924015 1.58 Down NM_001122948 clone MGC:18479 IMAGE:3983850) Cyclin-dependent kinase-like 2 (CDC2-related 2.37351 1.716655 1.58 Down NM_016912 kinase) (Cdkl2), transcript variant 1, mRNA 5.09444 4.436445 1.58 Down chr8:10886200- chr8:10886200-10905925_R 10905925_R Erythropoietin receptor, mRNA (cDNA clone 5.53519 4.874185 1.58 Down NM_010149 IMAGE:3487672) CDNA sequence BC049692, mRNA (cDNA clone 4.56405 5.221185 1.58 Up NAP114398-1 IMAGE:6705539) Hexokinase 1 (Hk1), nuclear gene encoding 4.59139 5.25011 1.58 Up NM_001146100 mitochondrial protein, transcript variant 2, mRNA 6.06789 5.408235 1.58 Down NM_028044 Calponin 3, acidic (Cnn3), mRNA Regulator of G-protein signaling 11, mRNA (cDNA 8.64959 7.992585 1.58 Down NM_001081069 clone IMAGE:3666182) Mitochondrial carrier homolog 2 (C. elegans), ENSMUST00000 mRNA (cDNA clone MGC:49067 3.77146 3.108975 1.58 Down 168705 IMAGE:5323415) 4.330135 3.66915 1.58 Down NM_152815 Lines homolog 2 (Drosophila) (Lins2), mRNA Serine/arginine repetitive matrix 2, mRNA (cDNA 3.38171 2.7208 1.58 Down NM_175229 clone IMAGE:5354975) TRM2 tRNA methyltransferase 2 homolog A (S. 6.78309 6.122885 1.58 Down NM_001081000 cerevisiae) (Trmt2a), transcript variant 3, mRNA 6.72159 6.061285 1.58 Down NM_029075 Stx11 3.12762 2.463895 1.58 Down AK148969 Transcribed locus 6.14859 5.491685 1.58 Down NR_002888 Vmn2r-ps14 6.08854 5.426785 1.58 Down NM_053202 Forkhead box P1 (Foxp1), mRNA Solute carrier family 19 (sodium/hydrogen exchanger), member 1, mRNA (cDNA clone 6.91504 6.256635 1.58 Down NM_031196 MGC:18428 IMAGE:4239690) 8.12134 7.461735 1.58 Down A_55_P1953377 LUC7-like 2 (S. cerevisiae) (Luc7l2), mRNA 0.95566 0.293105 1.58 Down A_55_P2054684 Olfactory receptor 688 (Olfr688), mRNA ENSMUST00000 9.35609 8.700035 1.58 Down 029611 Lef1 Interleukin 1 receptor, type I (Il1r1), transcript 2.3731 1.714025 1.58 Down NM_008362 variant 1, mRNA 3.267115 2.60736 1.58 Down NM_001037177 Transcription factor NFAT1-D chr2:104398943- -1.570905 -0.91944 1.57 Up 104412968_F chr2:104398943-104412968_F CDNA sequence BC022651, mRNA (cDNA clone -1.247845 -0.594265 1.57 Up NM_001142792 MGC:31268 IMAGE:4216812) -0.755335 -1.405185 1.57 Down AK139810 Transcribed locus -1.713775 -1.067055 1.57 Up XM_003086431 Gm1043 chr18:46954653- -0.471695 -1.12344 1.57 Down 46955671_F chr18:46954653-46955671_F Trefoil factor 3, intestinal, mRNA (cDNA clone -0.39149 0.25929 1.57 Up NM_011575 MGC:14072 IMAGE:4216708) -1.464455 -2.116945 1.57 Down NM_146573 Olfactory receptor 1002 (Olfr1002), mRNA chr1:121054422- -1.54522 -0.896065 1.57 Up 121055142_F chr1:121054422-121055142_F Transmembrane emp24 protein transport domain -1.157785 -1.806915 1.57 Down AK042931 containing 5 (Tmed5), mRNA chr2:143988645- -1.8301 -1.17902 1.57 Up 143993945_F chr2:143988645-143993945_F -1.745525 -2.39183 1.57 Down NR_027848 4930479M11Rik -1.493845 -0.84073 1.57 Up NM_020015 Melanoma antigen, family A, 1 (Magea1), mRNA FERM and PDZ domain containing 1, mRNA -1.238335 -1.891265 1.57 Down NM_001081172 (cDNA clone IMAGE:4500789) ENSMUST00000 Defensin beta 30, mRNA (cDNA clone -1.137095 -1.79025 1.57 Down 100490 MGC:163815 IMAGE:40130461) Phosphodiesterase 6H, cGMP-specific, cone, gamma -2.020585 -1.370145 1.57 Up NM_023898 (Pde6h), mRNA chr6:11994002- -0.43822 -1.089415 1.57 Down 11997859_F chr6:11994002-11997859_F chr12:16003706- -1.690985 -2.33931 1.57 Down 16022581_R chr12:16003706-16022581_R chr18:6144775- -1.16639 -1.819035 1.57 Down 6202105_F chr18:6144775-6202105_F chr5:122982442- -1.25529 -1.909205 1.57 Down 123000053_R chr5:122982442-123000053_R chr4:101010948- -0.834505 -1.48387 1.57 Down 101032148_F chr4:101010948-101032148_F chr11:102983499 -1.23575 -1.88951 1.57 Down -102994170_F chr11:102983499-102994170_F -0.552245 -1.20287 1.57 Down NM_021412 Matrix metalloproteinase 19 -0.687635 -1.34101 1.57 Down AK084979 Transcribed locus chr12:15774073- -1.845425 -1.19266 1.57 Up 15777144_R chr12:15774073-15777144_R Cannabinoid receptor 2 (macrophage), mRNA -0.30435 -0.951065 1.57 Down A_55_P2146546 (cDNA clone MGC:36085 IMAGE:5098695) chr12:82457625- -0.683535 -1.33201 1.57 Down 82476325_R chr12:82457625-82476325_R Pyrin and HIN domain family, member 1, mRNA -1.80694 -1.151725 1.57 Up NM_175026 (cDNA clone MGC:130358 IMAGE:40056703) chr19:21653968- -0.45156 0.196255 1.57 Up 21671718_R chr19:21653968-21671718_R KH domain containing 1C, mRNA (cDNA clone -1.214385 -0.56172 1.57 Up NM_001033904 MGC:175998 IMAGE:9055649) RIKEN cDNA 9530008L14 gene, mRNA (cDNA -1.63312 -0.9791 1.57 Up NM_001145875 clone MGC:29256 IMAGE:5055136) chr15:66684765- -1.64046 -0.99317 1.57 Up 66685491_F chr15:66684765-66685491_F ENSMUST00000 -1.50088 -0.84811 1.57 Up 162547 Ribosomal protein L31 (Rpl31), mRNA Carbonyl reductase 2, mRNA (cDNA clone -0.97515 -0.32715 1.57 Up NM_007621 MGC:18465 IMAGE:4219349) chr10:119960546 -0.63534 0.014335 1.57 Up -119979696_R chr10:119960546-119979696_R chr13:104591573 0.505965 1.159305 1.57 Up -104599048_F chr13:104591573-104599048_F 0.67259 1.326185 1.57 Up NM_173437 Neuron navigator 1, mRNA (cDNA clone IMAGE:5055436) Guanine nucleotide exchange factor OSTIII mRNA, 0.992305 1.647515 1.57 Up NM_178076 complete cds, alternatively spliced RIKEN cDNA 330010C22 gene, mRNA (cDNA 0.7223 0.07114 1.57 Down NM_001033489 clone IMAGE:5357632) 2.465455 1.810815 1.57 Down NM_018763 Carbohydrate sulfotransferase 2 (Chst2), mRNA Hepatitis A virus cellular receptor 1 (Havcr1), 3.302645 3.951345 1.57 Up AF399829 mRNA chr6:121053274- 0.83313 1.481355 1.57 Up 121053553_R chr6:121053274-121053553_R RIKEN cDNA 1700025K23 gene, mRNA (cDNA 4.25529 4.910335 1.57 Up NM_183254 clone MGC:198709 IMAGE:9054290) 1.278085 0.62335 1.57 Down NR_033305 AA388235 chr2:165802256- 1.50837 2.15695 1.57 Up 165805186_R chr2:165802256-165805186_R Family with sequence similarity 126, member B, mRNA (cDNA clone MGC:76460 2.930865 2.281315 1.57 Down NM_172513 IMAGE:30431671) RIKEN cDNA 2810474O19 gene, mRNA (cDNA 1.207925 0.553675 1.57 Down NM_026054 clone IMAGE:4952280) chr1:137689555- 1.83309 1.180765 1.57 Down 137692960_R chr1:137689555-137692960_R 2.001535 2.648525 1.57 Up NM_001081066 CDNA clone IMAGE:9053460 Synaptotagmin-like 3, mRNA (cDNA clone 1.04454 1.698835 1.57 Up NM_031395 MGC:31134 IMAGE:4166796) Fibroblast growth factor receptor 1, mRNA (cDNA 4.271935 4.921985 1.57 Up NM_010206 clone MGC:25398 IMAGE:4037899) chr17:17462450- 2.961265 2.311145 1.57 Down 17488725_F chr17:17462450-17488725_F Ferric-chelate reductase 1, mRNA (cDNA clone 2.612995 1.96049 1.57 Down NM_001113478 MGC:36179 IMAGE:5344922) Coiled-coil domain containing 116 (Ccdc116), 1.92229 1.27427 1.57 Down NM_029779 mRNA Chitinase domain containing 1, mRNA (cDNA clone 2.864525 3.51311 1.57 Up NM_026522 MGC:6792 IMAGE:2647540) Synaptotagmin-like 3, mRNA (cDNA clone 4.287805 4.940685 1.57 Up NM_031395 MGC:31134 IMAGE:4166796) Splicing factor, arginine/serine-rich 17b, mRNA 0.69775 0.04275 1.57 Down NM_001081956 (cDNA clone IMAGE:40130194) chr6:31017987- 1.652985 1.004645 1.57 Down 31174287_R chr6:31017987-31174287_R CD63 antigen, mRNA (cDNA clone MGC:6087 5.00959 5.661085 1.57 Up NM_001042580 IMAGE:3157993) B-cell leukemia/lymphoma 10, mRNA (cDNA clone 5.88449 5.229285 1.57 Down NM_009740 MGC:36096 IMAGE:4976147) 4.57199 3.92576 1.57 Down NM_001163454 Prorsd1 6.64309 7.294035 1.57 Up NM_011173 Of protein S gene Serine protease inhibitor, Kunitz type 1, mRNA 2.20765 1.560875 1.57 Down NM_016907 (cDNA clone MGC:6844 IMAGE:2650110) 1.940165 2.592405 1.57 Up NM_172571 Structural protein FBF1 (Fbf1) 6.78444 6.129985 1.57 Down NM_007901 Sphingosine-1-phosphate receptor 1 (S1pr1), mRNA Aldehyde dehydrogenase 1 family, member L2 0.366615 1.02161 1.57 Up NM_153543 (Aldh1l2), mRNA Non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human), mRNA (cDNA clone 5.09299 4.438365 1.57 Down NM_023647 MGC:46749 IMAGE:4482150) Cortexin 1, mRNA (cDNA clone MGC:25920 0.93606 0.282385 1.57 Down NM_183315 IMAGE:4224851) ENSMUST00000 Pyruvate kinase, muscle, mRNA (cDNA clone 9.05429 9.705485 1.57 Up 082407 MGC:11908 IMAGE:3598842) Eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked, mRNA (cDNA clone 3.92922 3.282795 1.57 Down A_55_P2093770 IMAGE:5029974) 9.44254 10.096635 1.57 Up NM_033444 Chloride intracellular channel 1 (Clic1), mRNA 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (Atic), 7.35359 6.699185 1.57 Down NM_026195 mRNA Tetratricopeptide repeat domain 21B (Ttc21b), 4.84519 4.19307 1.57 Down NM_001047604 mRNA 10.30399 9.651085 1.57 Down NM_139198 C15 protein 2.6794 2.03016 1.57 Down NM_013922 KRAB-zinc finger protein KID3 (Kid3) Embigin, mRNA (cDNA clone MGC:21425 8.72184 8.072335 1.57 Down NM_010330 IMAGE:4500922) CDNA sequence BC023829, mRNA (cDNA clone 3.32747 2.67578 1.57 Down NM_001033328 MGC:178934 IMAGE:9053926) Polymerase (RNA) II (DNA directed) polypeptide I 6.02759 5.376135 1.57 Down NM_027259 (Polr2i), mRNA 5.36229 6.014035 1.57 Up NM_145512 SFT2 domain containing 2 (Sft2d2), mRNA 2.807175 2.15343 1.57 Down NAP093863-001 NAP093863-001 8.25849 8.907635 1.57 Up FJ654103 FJ654103 Strain DBA/2J thiopurine S-methyltransferase 2.866795 2.211935 1.57 Down AF037047 (Tpmt) pseudogene, mRNA sequence 6.14054 5.487935 1.57 Down NM_001033126 CD27 antigen (Cd27) mRNA RIKEN cDNA C030027K23 gene, mRNA (cDNA 4.96924 4.31958 1.57 Down NM_001145978 clone IMAGE:5012822) 7.41179 6.758935 1.57 Down NM_007930 Ectodermal-neural cortex 1 (Enc1), mRNA 4.075645 4.72266 1.57 Up NM_001163447 Mapk8ip3 chr14:49314574- 8.32614 7.673835 1.57 Down 49358174_R chr14:49314574-49358174_R Transmembrane channel-like gene family 5 (Tmc5), -1.63706 -2.276285 1.56 Down NM_001105252 transcript variant 1, mRNA Vinculin, mRNA (cDNA clone MGC:6134 -1.34428 -1.982635 1.56 Down NM_009502 IMAGE:3495710) chr1:162965309- -0.553235 -1.19286 1.56 Down 162970704_R chr1:162965309-162970704_R ENSMUST00000 Tripartite motif-containing 25, mRNA (cDNA clone -1.926975 -1.284965 1.56 Up 150912 MGC:30340 IMAGE:4022161) -0.41176 -1.05711 1.56 Down NM_013666 St8sia5 CAP-GLY domain containing linker protein family, member 4, mRNA (cDNA clone MGC:30350 -1.72069 -1.07949 1.56 Up NM_175378 IMAGE:4920788) -0.285305 -0.92426 1.56 Down NM_174998 NVP-2 mRNA for neural visinin-like protein 2 chrX:47893703- -1.50074 -2.142065 1.56 Down 47996700_R chrX:47893703-47996700_R Yamaguchi sarcoma viral (v-yes) oncogene homolog 1, mRNA (cDNA clone MGC:18632 -0.30377 -0.942105 1.56 Down NM_009535 IMAGE:3989783) chr13:34240528- -1.456965 -2.094775 1.56 Down 34240965_R chr13:34240528-34240965_R NOX1 mRNA for NADPH oxidase 1, partial cds, -0.701605 -1.342235 1.56 Down A_55_P1997911 alternative splicing; NOX1 a-type mRNA -1.802585 -1.16 1.56 Up NM_146889 Olfactory receptor 1302 (Olfr1302), mRNA -1.67098 -1.028025 1.56 Up NM_007773 Crystallin, beta B2 (Crybb2), mRNA -1.48038 -2.121135 1.56 Down NM_019754 Transgelin 3 (Tagln3), mRNA chr9:96664617- -0.76859 -0.12371 1.56 Up 96683617_F chr9:96664617-96683617_F -1.11478 -1.758775 1.56 Down A_55_P2043569 Transcribed locus ENSMUST00000 Connective tissue growth factor, mRNA (cDNA -1.16068 -1.803445 1.56 Down 046116 clone MGC:8122 IMAGE:3589136) chr3:19793699- -1.37872 -0.73745 1.56 Up 19822899_R chr3:19793699-19822899_R Transcribed locus, strongly similar to XP_001477766.1 PREDICTED: hypothetical protein -0.633265 -1.27532 1.56 Down AK132952 [Mus musculus] PREDICTED: Mus musculus hypothetical protein -2.081905 -1.440485 1.56 Up AK043982 LOC100043050 (LOC100043050), mRNA Olfactomedin-like 2B, mRNA (cDNA clone -0.89447 -1.540615 1.56 Down NM_177068 IMAGE:5353638) ENSMUST00000 -1.669665 -1.028795 1.56 Up 048109 ENSMUST00000048109 Solute carrier family 29 (nucleoside transporters), -1.146745 -1.787225 1.56 Down NM_023596 member 3 (Slc29a3), mRNA -1.927665 -1.282475 1.56 Up BC042796 CDNA clone IMAGE:3992984 ENSMUST00000 Fatty acid binding protein 12, mRNA (cDNA clone -1.32415 -0.687165 1.56 Up 160580 MGC:31586 IMAGE:4505673) -0.84834 -0.2069 1.56 Up XM_003085596 LOC100504642 -1.661865 -1.018175 1.56 Up BF540204 Transcribed locus -1.62893 -0.984045 1.56 Up NM_153100 Receptor transporter protein 3 (Rtp3), mRNA chr9:34192364- -1.326165 -0.68392 1.56 Up 34192810_R chr9:34192364-34192810_R Collagen, type II, alpha 1, mRNA (cDNA clone -0.41008 0.22815 1.56 Up NM_001113515 IMAGE:4506267) RIKEN cDNA B830028B13 gene -1.8627 -1.217865 1.56 Up NM_001143802 (B830028B13Rik), mRNA -0.21266 -0.853505 1.56 Down NAP115343-1 NAP115343-1 -1.875315 -1.23021 1.56 Up NR_003624 Gm10319 -0.341675 -0.980155 1.56 Down NM_011440 Sox14 chr4:53315503- -1.925165 -1.287665 1.56 Up 53316050_F chr4:53315503-53316050_F chr10:120069727 -0.840355 -0.199285 1.56 Up -120136259_R chr10:120069727-120136259_R -0.75513 -1.397375 1.56 Down XM_003084760 9530004P13Rik chr5:74487385- -0.197025 -0.835575 1.56 Down 74497428_R chr5:74487385-74497428_R -0.264215 0.37798 1.56 Up XR_105257 LOC100503238 ENSMUST00000 Zinc finger protein 259, mRNA (cDNA clone 0.23732 -0.401785 1.56 Down 112511 MGC:29104 IMAGE:5067274) chr12:109994730 0.23559 -0.40894 1.56 Down -109995062_R chr12:109994730-109995062_R Folate receptor alpha precursor (FR-alpha) mRNA, 0.08153 0.721835 1.56 Up NM_008034 alternatively spliced 0.48335 -0.153715 1.56 Down NM_146953 Olfactory receptor 531 (Olfr531), mRNA 0.91667 0.270535 1.56 Down NM_001162904 Mdm1 chr11:68200716- 0.984295 0.339795 1.56 Down 68214458_R chr11:68200716-68214458_R PREDICTED: Mus musculus RIKEN cDNA 1700031M16 gene, transcript variant 2 1.091645 0.44672 1.56 Down A_55_P2008801 (1700031M16Rik), mRNA chr8:122712014- 1.25202 1.8978 1.56 Up 122732520_R chr8:122712014-122732520_R FBJ osteosarcoma oncogene, mRNA (cDNA clone 2.45403 1.809645 1.56 Down NM_010234 MGC:36690 IMAGE:2582234) 1.58658 0.948825 1.56 Down NM_001160345 Svip Kinase non-catalytic C-lobe domain (KIND) containing 1, mRNA (cDNA clone MGC:183698 1.723435 2.363855 1.56 Up NM_177261 IMAGE:9087698) chr2:181663381- 2.99464 3.63559 1.56 Up 181664097_F chr2:181663381-181664097_F MACRO domain containing 2, mRNA (cDNA clone 0.964285 0.31977 1.56 Down NM_028387 IMAGE:1429747) UCHL5 interacting protein (Uchl5ip), transcript 2.264925 2.902545 1.56 Up NM_207104 variant 1, mRNA 0.25124 0.893435 1.56 Up XM_003084562 LOC100503583 Regulator of G-protein signaling 9-2 isoform 3.114005 3.75734 1.56 Up NM_011268 (RGS9) chr13:107822042 1.394145 0.7557 1.56 Down -107823753_F chr13:107822042-107823753_F chr1:138442536- 0.984665 1.626035 1.56 Up 138520766_F chr1:138442536-138520766_F Zinc finger protein 397, mRNA (cDNA clone 2.49483 1.85368 1.56 Down NM_027007 IMAGE:5042893) 4.85569 4.210305 1.56 Down NM_177471 Coiled-coil domain containing 69 (Ccdc69), mRNA 1.743535 1.09971 1.56 Down ENSMUST00000 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58, 028141 mRNA (cDNA clone IMAGE:40095873) 1.480885 0.841845 1.56 Down NM_021470 Ring finger protein 32 (Rnf32), mRNA Protein tyrosine phosphatase, receptor type, J (Ptprj), 4.61039 3.96492 1.56 Down NM_008982 transcript variant 1, mRNA RNA binding motif, single stranded interacting protein 1, mRNA (cDNA clone MGC:25244 4.080305 4.720185 1.56 Up NM_020296 IMAGE:4527742) chr1:63163019- 3.48904 2.85028 1.56 Down 63164281_F chr1:63163019-63164281_F NIMA (never in mitosis gene a)-related expressed kinase 1, mRNA (cDNA clone MGC:198796 2.391455 1.751955 1.56 Down NM_175089 IMAGE:9054377) Amyloid beta (A4) precursor protein-binding, family A, member 3, mRNA (cDNA clone MGC:7481 5.81879 5.180435 1.56 Down NM_018758 IMAGE:3490710) 2.592935 1.949505 1.56 Down AK034303 CDNA clone IMAGE:30840270 PREDICTED: Mus musculus similar to lethal (3) 2.156915 1.51887 1.56 Down BY231855 IX-14 CG3953-PA (LOC100042676), mRNA C2 calcium-dependent domain containing 3 (C2cd3), 4.35396 3.715365 1.56 Down NM_001017985 mRNA SID1 transmembrane family, member 1, mRNA 4.171315 3.531335 1.56 Down NM_198034 (cDNA clone MGC:32412 IMAGE:5039343) RNA polymerase II associated protein 2 (Rpap2), 6.23989 5.601935 1.56 Down NM_144911 mRNA 4.242385 3.601825 1.56 Down NM_026739 MKIAA0895 protein 1.94682 1.303595 1.56 Down NAP095248-001 NAP095248-001 Testosterone regulated apoptosis inducer and tumor 4.97579 4.333585 1.56 Down NM_001113401 suppressor (Traits) 2.107525 2.752865 1.56 Up NM_178884 Obscurin-like 1 (Obsl1), mRNA ENSMUST00000 6.45379 5.814635 1.56 Down 137941 ENSMUST00000137941 Furin (paired basic amino acid cleaving enzyme) 7.90534 7.263185 1.56 Down NM_011046 (Furin), mRNA 2.56334 3.20573 1.56 Up NM_009909 Interleukin 8 receptor, beta (Il8rb), mRNA Chromatin modifying protein 4B, mRNA (cDNA 8.93684 8.295635 1.56 Down NM_029362 clone MGC:19416 IMAGE:3485793) Microsomal glutathione S-transferase 3, mRNA 4.65479 4.01679 1.56 Down NM_025569 (cDNA clone MGC:35738 IMAGE:5372427) Solute carrier family 37 (glucose-6-phosphate 8.91069 8.266285 1.56 Down NM_008063 transporter), member 4 (Slc37a4), mRNA 4.26802 4.90517 1.56 Up NM_031393 Synaptotagmin-like 1 (Sytl1), mRNA ADP-ribosylation factor-like 15, mRNA (cDNA 3.367665 4.00769 1.56 Up NM_172595 clone MGC:178549 IMAGE:9053541) Metal response element binding transcription factor 1, mRNA (cDNA clone MGC:18436 3.645815 3.0082 1.56 Down NM_008636 IMAGE:4210829) RIKEN cDNA D130062J10 gene, mRNA (cDNA 5.09824 4.454035 1.56 Down AK051660 clone IMAGE:1264858) 4.301995 3.664995 1.56 Down NM_177739 MKIAA1084 protein 9.91189 9.266135 1.56 Down XM_891513 Gm6718 7.04394 6.403385 1.56 Down NM_017401 Polymerase (DNA directed), mu (Polm), mRNA Transmembrane emp24 domain containing 8, mRNA 5.03514 4.39216 1.56 Down NM_001033475 (cDNA clone MGC:183771 IMAGE:9087771) 8.93674 8.299735 1.56 Down NM_026784 Phosphomevalonate kinase (Pmvk), mRNA chr16:43623175- 4.59724 3.9577 1.56 Down 43624069_F chr16:43623175-43624069_F 6.56679 5.927535 1.56 Down A_55_P2144391 Emr1 NmrA-like family domain containing 1 (Nmral1), 3.8222 3.1847 1.56 Down NM_026393 mRNA Solute carrier family 16 (monocarboxylic acid 3.183495 2.539455 1.56 Down NM_172371 transporters), member 13 (Slc16a13), mRNA chr1:185808525- 1.635945 2.277695 1.56 Up 185826139_R chr1:185808525-185826139_R chr16:11024315- 1.621965 0.97994 1.56 Down 11055740_F chr16:11024315-11055740_F Avian reticuloendotheliosis viral (v-rel) oncogene related B, mRNA (cDNA clone MGC:25383 7.28799 6.647935 1.56 Down NM_009046 IMAGE:4485540) 2.2891 2.92972 1.56 Up XR_105537 4921525O09Rik Poly (ADP-ribose) polymerase family, member 12, -1.436325 -2.064485 1.55 Down NM_172893 mRNA (cDNA clone IMAGE:3989516) Peroxisome proliferator activated receptor alpha, mRNA (cDNA clone MGC:18607 -1.99095 -1.358725 1.55 Up NM_011144 IMAGE:4222384) RIKEN cDNA 9930021J17 gene, mRNA (cDNA -1.45511 -2.090065 1.55 Down NM_172682 clone IMAGE:3994353) chr7:86651948- -1.50692 -2.14238 1.55 Down 86675223_F chr7:86651948-86675223_F -1.60253 -2.23845 1.55 Down NM_001104623 Vomeronasal 2, receptor 12 (Vmn2r12), mRNA -2.00267 -1.373645 1.55 Up NM_001177732 Plch1 chr2:31001736- -1.5143 -0.884715 1.55 Up 31006911_F chr2:31001736-31006911_F chr5:123582742- -1.409375 -0.778985 1.55 Up 123588117_F chr5:123582742-123588117_F -1.36761 -0.73848 1.55 Up NM_054090 Olfactory receptor 73 (Olfr73), mRNA -2.012625 -1.37877 1.55 Up NR_030683 Gm14207 chr7:6296401- -0.33405 -0.961925 1.55 Down 6311486_F chr7:6296401-6311486_F chr9:53613193- -1.74552 -2.38102 1.55 Down 53613871_F chr9:53613193-53613871_F chr3:36280098- -1.222775 -0.58664 1.55 Up 36347798_F chr3:36280098-36347798_F -1.331465 -1.96324 1.55 Down AV575454 Transcribed locus -1.31985 -1.956455 1.55 Down NM_138955 ABCG4 (Abcg4) -1.42809 -2.060075 1.55 Down NM_021885 Tubby candidate gene, mRNA (cDNA clone IMAGE:4527484) Triggering receptor expressed on myeloid cells-like 6 (Treml6) mRNA, complete cds, alternatively -1.365745 -1.99351 1.55 Down A_55_P2110783 spliced chrX:100688896- -1.9773 -1.34255 1.55 Up 100701764_F chrX:100688896-100701764_F chr12:17350856- -1.216365 -1.850305 1.55 Down 17355179_R chr12:17350856-17355179_R Potassium large conductance calcium-activated ENSMUST00000 channel, subfamily M, beta member 2 (Kcnmb2), -0.5179 -1.152705 1.55 Down 106800 mRNA -1.064115 -1.69665 1.55 Down C80360 Transcribed locus -1.537045 -2.17119 1.55 Down AK043285 Transcribed locus chr2:25778863- -1.550015 -2.184525 1.55 Down 25780329_F chr2:25778863-25780329_F -1.310505 -1.944195 1.55 Down NM_016723 Uchl3 mRNA for UCH-L3 chr18:5988500- -0.94646 -1.575655 1.55 Down 6022000_R chr18:5988500-6022000_R chr17:7025616- -1.76447 -1.1285 1.55 Up 7033491_R chr17:7025616-7033491_R chr12:88216447- -0.771405 -1.40443 1.55 Down 88224965_R chr12:88216447-88224965_R chr4:141100989- -1.76604 -1.13478 1.55 Up 141106639_R chr4:141100989-141106639_R -1.873205 -1.24074 1.55 Up XM_001474011 LOC100045292 -1.648625 -1.01913 1.55 Up NM_028622 Late cornified envelope 1C (Lce1c), mRNA chrX:47893703- -0.301175 -0.93487 1.55 Down 47996700_F chrX:47893703-47996700_F Leucine-rich and immunoglobulin-like domains 3 -0.372835 -1.003565 1.55 Down NM_177152 (Lrig3) -0.388905 -1.02398 1.55 Down TC1682426 TC1682426 chr5:75389503- -0.26588 0.36232 1.55 Up 75396250_F chr5:75389503-75396250_F chr9:96664617- -0.818125 -0.18995 1.55 Up 96683617_R chr9:96664617-96683617_R -0.9498 -1.58077 1.55 Down NM_009686 FE65-like protein -1.393025 -0.757195 1.55 Up NM_029686 Polycystic kidney disease 1 like 2 (Pkd1l2), mRNA -1.261145 -0.63134 1.55 Up NM_009645 Activation-induced cytidine deaminase (AID) ENSMUST00000 Pyruvate kinase, muscle, mRNA (cDNA clone -0.552295 -1.18532 1.55 Down 164552 MGC:11908 IMAGE:3598842) chr10:81615171- -0.38632 -1.0208 1.55 Down 81615810_F chr10:81615171-81615810_F -0.364115 -0.99479 1.55 Down NM_010635 Kruppel-like factor 1 (erythroid) (Klf1), mRNA NK-3 transcription factor, locus 1 (Drosophila) 0.537355 1.16762 1.55 Up A_55_P1952216 (Nkx3-1), mRNA 0.77222 1.4056 1.55 Up AK157637 Gm10674 0.338985 0.96979 1.55 Up NM_020258 Solute carrier family 37 (glycerol-3-phosphate transporter), member 2, mRNA (cDNA clone IMAGE:4913507) chr6:131272447- 1.46453 2.09626 1.55 Up 131303615_R chr6:131272447-131303615_R Solute carrier family 32 (GABA vesicular 1.150715 1.78711 1.55 Up NM_009508 transporter), member 1 (Slc32a1), mRNA 1.33316 1.96495 1.55 Up NM_013596 Melanocortin 5 receptor (Mc5r), mRNA Zinc finger protein 11, mRNA (cDNA clone 0.20133 -0.435395 1.55 Down NM_172462 MGC:170942 IMAGE:8862337) ENSMUST00000 0.71761 1.34965 1.55 Up 140371 Transcribed locus PREDICTED: Mus musculus RIKEN cDNA 0.469795 -0.16297 1.55 Down AK007072 1700094M24 gene (1700094M24Rik), mRNA chr9:106170918- 1.26333 1.89417 1.55 Up 106177894_F chr9:106170918-106177894_F Bruno-like 5, RNA binding protein (Drosophila), 1.325075 0.695365 1.55 Down NM_176954 mRNA (cDNA clone IMAGE:5701128) Kazal-type serine peptidase inhibitor domain 1, mRNA (cDNA clone MGC:144546 1.60512 2.24068 1.55 Up NM_178929 IMAGE:40103018) chr7:3338500- 1.27741 1.90944 1.55 Up 3360725_R chr7:3338500-3360725_R Protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), 1.32425 1.958125 1.55 Up NM_001144855 alpha 4 (Ppfia4), mRNA 1.519165 2.151575 1.55 Up TC1700900 TC1700900 PREDICTED: Mus musculus hypothetical protein 1.468795 2.099525 1.55 Up BE633986 LOC100040850 (LOC100040850), mRNA chr10:39386908- 1.655765 1.027575 1.55 Down 39390947_F chr10:39386908-39390947_F 1.6366 1.00621 1.55 Down NM_016971 Interleukin 22 (Il22), mRNA chr10:81165750- 0.427535 1.06286 1.55 Up 81236400_F chr10:81165750-81236400_F ENSMUST00000 2.799795 3.42891 1.55 Up 062980 Transmembrane protein 106C (Tmem106c), mRNA 1.65993 1.02492 1.55 Down TC1721234 TC1721234 Predicted gene, EG433016, mRNA (cDNA clone 4.5318 5.160685 1.55 Up NM_001082547 MGC:182254 IMAGE:9056148) 2.17795 1.549715 1.55 Down NM_026270 AKT1 substrate 1 (proline-rich) (Akt1s1), mRNA SMT3 suppressor of mif two 3 homolog 3 (yeast) 4.141705 4.778325 1.55 Up NM_019929 (Sumo3), mRNA Insulin-like growth factor binding protein 6, mRNA 1.6172 2.249135 1.55 Up NM_008344 (cDNA clone MGC:14073 IMAGE:4224052) chr13:104591573 1.864445 1.236665 1.55 Down -104599048_R chr13:104591573-104599048_R TXK tyrosine kinase (Txk), transcript variant 2, 5.45684 4.820235 1.55 Down NM_013698 mRNA H1 histone family, member O, oocyte-specific 1.79782 2.432525 1.55 Up NM_138311 (H1foo), mRNA LIM and SH3 protein 1, mRNA (cDNA clone 1.995525 1.36287 1.55 Down NM_010688 MGC:5975 IMAGE:3490532) 1.98748 1.35133 1.55 Down NM_175478 Synaptic adhesion-like molecule 4 ATPase, Ca++ transporting, plasma membrane 1, 5.30969 5.945985 1.55 Up NM_026482 mRNA (cDNA clone IMAGE:4503278) chr3:19179899- 2.98346 2.35464 1.55 Down 19216399_F chr3:19179899-19216399_F 4.155215 4.791235 1.55 Up NM_016661 S-adenosylhomocysteine hydrolase (Ahcy), mRNA SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1, 1.400945 0.772285 1.55 Down NM_031842 mRNA (cDNA clone MGC:30227 ENSMUST00000 Olfactory receptor 772, mRNA (cDNA clone 5.42099 4.786835 1.55 Down 098571 MGC:170738 IMAGE:8862133) 1.111885 0.47655 1.55 Down NM_178662 Caytaxin (Atcay) Autophagy-related 4C (yeast) (Atg4c), transcript 2.12849 1.49411 1.55 Down NM_175029 variant 2, mRNA Purinergic receptor P2Y, G-protein coupled 1 1.85201 2.486475 1.55 Up NM_008772 (P2ry1), mRNA 5.44474 4.81022 1.55 Down NM_031178 Toll-like receptor 9 (Tlr9), mRNA chr4:59306575- 1.35279 1.982135 1.55 Up 59317850_R chr4:59306575-59317850_R Zinc finger, DHHC domain containing 1, mRNA 2.79751 2.16318 1.55 Down NM_175160 (cDNA clone MGC:36372 IMAGE:4984252) RIKEN cDNA 0610010F05 gene, mRNA (cDNA 1.44961 0.819915 1.55 Down NM_027860 clone MGC:105226 IMAGE:6848269) chr13:107812547 1.450985 0.817865 1.55 Down -107823601_F chr13:107812547-107823601_F chr9:75316023- 0.85296 0.22371 1.55 Down 75344401_F chr9:75316023-75344401_F 5.18954 4.552705 1.55 Down AJ251804 Polymerase (DNA directed), mu (Polm), mRNA CDNA sequence BC057552, mRNA (cDNA clone 4.90009 5.532435 1.55 Up NM_172502 MGC:66593 IMAGE:6403172) 8.05419 7.419635 1.55 Down NM_029023 Serine carboxypeptidase 1 (Scpep1), mRNA chr16:43623581- 3.62664 2.99631 1.55 Down 43642715_F chr16:43623581-43642715_F chr16:43623581- 2.167855 1.531515 1.55 Down 43642715_F chr16:43623581-43642715_F CDNA fis, clone TRACH2002862,highly similar to 6.32094 5.687485 1.55 Down NM_009968 QUINONE OXIDOREDUCTASE (EC 1.6.5.5) chr16:43635730- 2.39707 1.76567 1.55 Down 43639104_F chr16:43635730-43639104_F Oligonucleotide/oligosaccharide-binding fold containing 2B, mRNA (cDNA clone MGC:30353 6.11209 5.477635 1.55 Down NM_027257 IMAGE:5011571) NudC domain containing 1, mRNA (cDNA clone 2.78722 2.15822 1.55 Down NM_026149 MGC:37103 IMAGE:4952090) chr14:65430484- 3.788645 3.153205 1.55 Down 65432413_R chr14:65430484-65432413_R 4.60634 3.97647 1.55 Down NM_139227 Ataxin 7 (Atxn7), mRNA Actinin, alpha 1, mRNA (cDNA clone 2.13998 1.5097 1.55 Down NM_134156 IMAGE:3483627) 7.75224 7.118485 1.55 Down NR_027943 1110038B12Rik 5.22214 4.58634 1.55 Down NM_133746 Calcium homeostasis modulator 2 (Calhm2), mRNA NmrA-like family domain containing 1 (Nmral1), 5.81849 5.183885 1.55 Down NM_026393 mRNA 4.373865 5.007735 1.55 Up NM_008353 Interleukin 12 receptor, beta 1 (Il12rb1), mRNA Mitogen-activated protein kinase kinase kinase 5 5.02164 4.387725 1.55 Down NM_008580 (Map3k5), mRNA 2.67177 2.04232 1.55 Down NM_172842 Membrane associated adaptor protein LAX Glyoxylate reductase/hydroxypyruvate reductase/D- 4.59174 5.220535 1.55 Up NM_080289 glycerate dehydrogenase (Grhpr) Syndecan binding protein, mRNA (cDNA clone 4.89004 5.525235 1.55 Up NM_001098227 MGC:30224 IMAGE:4017442) Lectin, galactoside-binding, soluble, 3 binding 7.66039 7.028585 1.55 Down NM_011150 protein (Lgals3bp), mRNA Pleckstrin homology domain containing, family F (with FYVE domain) member 2, mRNA (cDNA 4.49644 3.85989 1.55 Down NM_175175 clone MGC:36376 IMAGE:4987735) 4.432985 3.797005 1.55 Down NM_152814 Zinc finger protein 566 (Zfp566), mRNA RIKEN cDNA 5730494M16 gene -1.26486 -0.640095 1.54 Up AK040234 (5730494M16Rik), transcript variant 2, mRNA chr10:93871635- -1.16275 -1.784095 1.54 Down 93873477_F chr10:93871635-93873477_F Fas apoptotic inhibitory molecule 2, mRNA (cDNA -1.29656 -0.672655 1.54 Up NM_028224 clone MGC:40667 IMAGE:5400222) Calpain 12, mRNA (cDNA clone MGC:41077 -1.29898 -1.919215 1.54 Down NM_001110807 IMAGE:1314413) chr18:38398058- -1.569965 -2.190715 1.54 Down 38409852_R chr18:38398058-38409852_R chr12:70213282- -0.499835 -1.12328 1.54 Down 70225157_R chr12:70213282-70225157_R chrX:20555593- -0.39009 -1.00961 1.54 Down 20591971_F chrX:20555593-20591971_F chr6:129151512- -1.282975 -0.658805 1.54 Up 129208737_F chr6:129151512-129208737_F chr6:148162552- -1.312495 -1.93654 1.54 Down 148176577_R chr6:148162552-148176577_R ENSMUST00000 -1.345105 -0.71854 1.54 Up 124164 Vomeronasal 1 receptor, C26 (V1rc26), mRNA chr1:162965001- -0.77434 -1.40111 1.54 Down 162966376_F chr1:162965001-162966376_F chr6:82608223- -0.935765 -0.311415 1.54 Up 82669023_R chr6:82608223-82669023_R -1.208495 -1.83341 1.54 Down KCNQ1ot1 KCNQ1ot1 chr5:44625083- -1.31295 -1.932 1.54 Down 44634763_F chr5:44625083-44634763_F chr10:6480075- -1.41421 -0.793255 1.54 Up 6603900_F chr10:6480075-6603900_F Glial cell line derived neurotrophic factor family -1.465175 -0.846935 1.54 Up NM_020014 receptor alpha 4 (Gfra4), transcript variant 2, mRNA -1.72128 -2.34137 1.54 Down AK134010 Utrophin, mRNA (cDNA clone IMAGE:5149431) -1.24943 -1.874455 1.54 Down NM_172771 Premature mRNA for mKIAA0856 protein Signal-regulatory protein beta 1 (Sirpb1), transcript -1.51965 -2.14483 1.54 Down NM_001002898 variant 3, mRNA Thyrotropin releasing hormone receptor 2 (Trhr2), -0.352105 0.27083 1.54 Up NM_133202 mRNA -0.291785 -0.910045 1.54 Down NM_007384 Brain sodium channel 1 alpha subunit (Accn1) -1.478315 -2.102085 1.54 Down NM_001167581 Gsdmcl1 chr16:21794415- -1.885415 -1.26307 1.54 Up 21815365_R chr16:21794415-21815365_R PREDICTED: Mus musculus RIKEN cDNA -1.53306 -0.908965 1.54 Up A_55_P2172364 5033428B15 gene (5033428B15Rik), mRNA Caspase recruitment domain family, member 9, mRNA (cDNA clone MGC:183936 -0.7244 -0.10361 1.54 Up NM_001037747 IMAGE:9087936) -0.742385 -0.11944 1.54 Up NM_010009 25-hydroxyvitamin D3 1alpha-hydroxylase -0.198555 0.42014 1.54 Up NM_008286 Strain B10.S/DvTe histamine receptor H2 (Hrh2) RIKEN cDNA E430004N04 gene, mRNA (cDNA -1.30012 -1.92653 1.54 Down A_55_P1972448 clone MGC:159189 IMAGE:40130001) chr9:41137539- -1.720215 -1.0951 1.54 Up 41353289_F chr9:41137539-41353289_F RIKEN cDNA 4930449I24 gene (4930449I24Rik), -1.5148 -2.13562 1.54 Down NM_026136 mRNA Olfactory receptor 523, mRNA (cDNA clone -1.84255 -1.22263 1.54 Up NM_146518 MGC:155556 IMAGE:8733989) PREDICTED: Mus musculus RIKEN cDNA -1.611655 -0.99118 1.54 Up AK008780 2210039B01 gene (2210039B01Rik), mRNA ENSMUST00000 -1.2233 -0.602295 1.54 Up 107197 Vomeroglandin Acetyl-Coenzyme A carboxylase beta, mRNA -0.589485 -1.21616 1.54 Down NM_133904 (cDNA clone IMAGE:4009364) Nucleosome assembly protein 1-like 3 (Nap1l3), -1.38938 -0.769635 1.54 Up NM_138742 mRNA 5-hydroxytryptamine (serotonin) receptor 1D -1.347415 -0.72889 1.54 Up NM_008309 (Htr1d), mRNA -0.93099 -0.308235 1.54 Up AK162207 EF-hand calcium binding domain 3 (Efcab3), mRNA -1.67909 -1.05479 1.54 Up NR_015540 4933400F21Rik chr9:121093500- -1.191225 -0.570545 1.54 Up 121104550_F chr9:121093500-121104550_F -1.25986 -0.638575 1.54 Up AK149136 Collagen, type XIX, alpha 1 (Col19a1), mRNA chr9:118291593- -1.735955 -1.112755 1.54 Up 118324230_F chr9:118291593-118324230_F Mitogen-activated protein kinase kinase kinase -0.62308 -1.247425 1.54 Down A_55_P2024205 kinase 3, mRNA (cDNA clone IMAGE:3603090) chr18:63463356- -0.967305 -1.589265 1.54 Down 63463691_F chr18:63463356-63463691_F ATPase, H+ transporting, lysosomal V1 subunit G3, mRNA (cDNA clone MGC:130214 -1.324 -0.70559 1.54 Up NM_177397 IMAGE:40052587) -1.020165 -0.39713 1.54 Up A_55_P2129057 Toll-like receptor 7 (Tlr7), mRNA Keratin associated protein 31-2, mRNA (cDNA -0.325375 0.29421 1.54 Up NM_001025244 clone MGC:182230 IMAGE:9056124) 0.3087 0.934465 1.54 Up NM_053176 Histidine-rich glycoprotein (Hrg), mRNA 0.55783 1.181195 1.54 Up H19 H19 PREDICTED: Mus musculus region containing RIKEN cDNA 1700028E10 gene; hypothetical 0.324245 0.947265 1.54 Up AK031407 protein A630054D14 (LOC625175), mRNA chr12:82500406- 0.129335 -0.49429 1.54 Down 82501102_F chr12:82500406-82501102_F Prostaglandin-endoperoxide synthase 1, mRNA 1.58328 0.963465 1.54 Down NM_008969 (cDNA clone MGC:28109 IMAGE:3968136) 0.72727 1.349045 1.54 Up AK050962 Transcribed locus Zinc finger protein 612, mRNA (cDNA clone 1.79793 1.17746 1.54 Down NM_175480 IMAGE:3586510) chr10:81680941- 4.967455 4.34483 1.54 Down 81704964_F chr10:81680941-81704964_F 0.581085 1.201395 1.54 Up NM_146588 Olfactory receptor 1030 (Olfr1030), mRNA chr18:57101890- 0.92289 0.302965 1.54 Down 57102541_F chr18:57101890-57102541_F chr8:34646787- 1.86611 1.24549 1.54 Down 34680312_F chr8:34646787-34680312_F chr4:123572090- 0.278525 -0.340435 1.54 Down 123581365_R chr4:123572090-123581365_R 0.800725 0.1764 1.54 Down NM_172939 Ankyrin repeat domain 57 (Ankrd57), mRNA RIKEN cDNA 4933402P03 gene, mRNA (cDNA 0.347665 -0.27293 1.54 Down NM_175368 clone MGC:169585 IMAGE:8860980) 0.239315 -0.38461 1.54 Down NM_016700 Mitogen-activated protein kinase 8 (Mapk8), mRNA Tumor necrosis factor receptor superfamily, member 1.83713 1.21879 1.54 Down NM_021349 13b (Tnfrsf13b), mRNA chr8:129336539- 2.117735 2.741275 1.54 Up 129400338_R chr8:129336539-129400338_R ENSMUST00000 Reticulon 4 receptor-like 1, mRNA (cDNA clone 1.696605 1.07057 1.54 Down 166446 MGC:40829 IMAGE:5368560) chr13:94182877- 1.60833 0.983295 1.54 Down 94203852_R chr13:94182877-94203852_R 4.74894 5.368685 1.54 Up NM_010889 Nebulin (Neb), mRNA ENSMUST00000 1.5372 2.157855 1.54 Up 059658 Calponin 3, acidic (Cnn3), mRNA ChaC, cation transport regulator-like 1 (E. coli) 2.850305 3.46949 1.54 Up NM_026929 (Chac1), mRNA chr16:43623581- 1.779245 1.15864 1.54 Down 43642715_F chr16:43623581-43642715_F chr13:98062189- 1.87596 1.25202 1.54 Down 98066613_F chr13:98062189-98066613_F Transcription elongation factor A (SII)-like 3, mRNA (cDNA clone MGC:35770 3.122385 2.499875 1.54 Down NM_001029978 IMAGE:5358255) Beta-transducin repeat containing protein, mRNA 2.486555 1.859815 1.54 Down NM_001037758 (cDNA clone MGC:7517 IMAGE:3491843) PREDICTED: Mus musculus similar to SR protein related family member (rsr-1) (LOC100040377), 3.99243 3.3737 1.54 Down XM_001474574 mRNA ENSMUST00000 2.525045 1.899215 1.54 Down 149537 Thyroid adenoma-associated protein (THADA) 4.00333 3.37642 1.54 Down NM_001082974 Neuralized-like 2 (Drosophila) (Neurl2), mRNA Transcribed locus, moderately similar to XP_001493377.1 PREDICTED: similar to Zinc 3.28592 2.661305 1.54 Down BB209673 finger and SCAN domain-containing protein Four and a half LIM domains 2, mRNA (cDNA 3.23763 3.864455 1.54 Up NM_010212 clone MGC:29060 IMAGE:5066565) 6.46034 5.837685 1.54 Down NM_133720 Cysteinyl leukotriene receptor 2 (Cysltr2), mRNA Rap guanine nucleotide exchange factor (GEF)-like 2.20628 1.581135 1.54 Down NM_001080925 1 (Rapgefl1), mRNA 6.29899 6.918485 1.54 Up NM_030694 Fragilis R ENSMUST00000 Family with sequence similarity 123, member A, 1.71884 1.09953 1.54 Down 152456 mRNA (cDNA clone IMAGE:5367534) 2.28154 1.660245 1.54 Down NR_027984 2810025M15Rik RIKEN cDNA 2810021B07 gene (2810021B07Rik), 3.55579 4.179775 1.54 Up NAP002592-003 mRNA chr6:66216675- 1.53049 0.90905 1.54 Down 66234475_R chr6:66216675-66234475_R chrX:98979320- 4.89104 4.27018 1.54 Down 98997145_F chrX:98979320-98997145_F 4.224665 3.59723 1.54 Down NM_001163833 Msl3l2 Protein phosphatase 1, regulatory (inhibitor) subunit 4.68784 4.06165 1.54 Down NM_146154 8 (Ppp1r8), mRNA N-terminal Asn amidase, mRNA (cDNA clone 3.74507 3.122625 1.54 Down A_55_P2117333 MGC:29106 IMAGE:5037501) 4.44184 3.81796 1.54 Down NM_001172074 3110009E18Rik ST6GalNAc VI mRNA for GD1 alpha/GT1a 5.16129 4.542165 1.54 Down NM_016973 alpha/GQ1b alpha synthase 3.21242 2.5922 1.54 Down NM_177594 Myotubularin homologous protein 3 9.09769 8.475985 1.54 Down NM_134152 Leupaxin Transmembrane protein 65, mRNA (cDNA clone 3.77555 3.15271 1.54 Down NM_175212 MGC:106261 IMAGE:2615937) chr17:3213918- 4.11942 3.498405 1.54 Down 3257944_F chr17:3213918-3257944_F Acidic (leucine-rich) nuclear phosphoprotein 32 family, member E, mRNA (cDNA clone 4.93609 5.557885 1.54 Up NM_023210 MGC:11640 IMAGE:3596597) 7.04759 6.425885 1.54 Down NM_008540 MAD homolog 4 (Drosophila) (Smad4), mRNA Amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein, mRNA (cDNA 6.44899 5.823485 1.54 Down NM_019456 clone MGC:28054 IMAGE:3707478 COMM domain containing 8, mRNA (cDNA clone 2.60638 1.98779 1.54 Down NM_178599 IMAGE:5251649) Serum/glucocorticoid regulated kinase 3 (Sgk3), 7.38549 6.767235 1.54 Down NM_133220 transcript variant 1, mRNA Dpy-19-like 3 (C. elegans), mRNA (cDNA clone 5.60764 4.982285 1.54 Down NM_178704 MGC:69854 IMAGE:6821433) Asparagine-linked glycosylation 8 homolog (yeast, 3.76401 4.386285 1.54 Up NM_199035 alpha-1,3-glucosyltransferase) (Alg8), mRNA 10.42369 9.797235 1.54 Down NM_029803 Interferon stimulated gene 12 (Isg12) PYD and CARD domain containing, mRNA (cDNA 8.46974 7.847985 1.54 Down NM_023258 clone MGC:6811 IMAGE:2648391) Killer cell lectin-like receptor, subfamily D, member 7.61479 6.988885 1.54 Down NM_010654 1 (Klrd1), mRNA Epidermal growth factor receptor pathway substrate 8, mRNA (cDNA clone MGC:18488 3.05315 2.42621 1.54 Down NM_007945 IMAGE:4240899) Radial spoke head 9 homolog (Chlamydomonas) 3.58316 2.958035 1.54 Down NM_029338 (Rsph9), mRNA Deltex 3-like (Drosophila), mRNA (cDNA clone 3.34626 2.72525 1.54 Down AK090152 MGC:169318 IMAGE:8860713) chr17:7002731- 2.32224 1.70125 1.54 Down 7032535_R chr17:7002731-7032535_R 2.88193 2.25758 1.54 Down NM_001161765 Fmo5 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 (Ctdsp2), 4.246115 3.62683 1.54 Down NM_001113470 transcript variant b, mRNA Sprouty homolog 1 (Drosophila), mRNA (cDNA 3.912345 3.287375 1.54 Down NM_011896 clone MGC:18307 IMAGE:3672353) Host cell factor C1 regulator 1 (XPO1-dependent), mRNA (cDNA clone MGC:99867 6.89539 6.269585 1.54 Down NM_181821 IMAGE:6818222) 6.61739 5.990885 1.54 Down NM_026001 Ribonuclease H2, subunit B (Rnaseh2b), mRNA BRCA2 and CDKN1A interacting protein (Bccip), 6.32634 5.706985 1.54 Down NM_025392 mRNA chr3:19179899- 2.028055 1.40846 1.54 Down 19216399_F chr3:19179899-19216399_F chr17:17342991- 5.07929 4.460415 1.54 Down 17343357_F chr17:17342991-17343357_F Spermatogenesis associated 20, mRNA (cDNA -1.900955 -1.28603 1.53 Up NM_144827 clone IMAGE:6771592) chr11:16834711- -1.175305 -0.56516 1.53 Up 16851125_R chr11:16834711-16851125_R Transcribed locus, strongly similar to XP_001475410.1 PREDICTED: hypothetical protein -0.98383 -0.373245 1.53 Up A_55_P1964907 [Mus musculus] chr16:29711373- -1.212915 -1.822545 1.53 Down 29712035_R chr16:29711373-29712035_R Ring finger protein 112, mRNA (cDNA clone -1.72687 -2.340635 1.53 Down NM_009548 MGC:46743 IMAGE:4506141) chr3:45081952- -0.67945 -1.29491 1.53 Down 45092352_F chr3:45081952-45092352_F chr17:33425193- -1.577455 -0.96491 1.53 Up 33449090_R chr17:33425193-33449090_R chr4:89032648- -1.26026 -1.87679 1.53 Down 89133273_F chr4:89032648-89133273_F -0.627275 -1.24425 1.53 Down NM_001177731 Mrap2 ENSMUST00000 -1.150555 -0.536875 1.53 Up 154878 Transcribed locus 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1, mRNA (cDNA clone MGC:36620 -1.37654 -1.99115 1.53 Down AK031297 IMAGE:5347038) chr14:61240427- -0.929095 -1.542795 1.53 Down 61325677_R chr14:61240427-61325677_R chr4:21683562- -1.733445 -2.349785 1.53 Down 21694344_F chr4:21683562-21694344_F -0.71058 -1.327165 1.53 Down NM_011449 Sperm autoantigenic protein 17 (Spa17), mRNA Transcribed locus, strongly similar to XP_001477107.1 PREDICTED: hypothetical protein -0.777725 -1.39396 1.53 Down AK080018 [Mus musculus] chr10:126818382 -1.491995 -2.10889 1.53 Down -126856582_F chr10:126818382-126856582_F chr7:151085617- -1.639765 -1.0259 1.53 Up 151100071_F chr7:151085617-151100071_F -1.67711 -1.06541 1.53 Up NM_001081025 Unknown mRNA -0.532715 -1.145435 1.53 Down AK138625 Transcribed locus Expressed sequence AA792892, mRNA (cDNA -1.46728 -2.076765 1.53 Down NM_178894 clone MGC:159137 IMAGE:40129949) PDZ and LIM domain 5, mRNA (cDNA clone -1.354265 -1.966695 1.53 Down A_55_P2001154 MGC:46824 IMAGE:4457868) -1.577635 -0.96146 1.53 Up NR_002867 Pax6os1 ENSMUST00000 -1.68773 -1.07127 1.53 Up 046454 Olfactory receptor 984 (Olfr984), mRNA -0.39655 -1.01169 1.53 Down NM_146507 Olfactory receptor 944 (Olfr944), mRNA -1.00037 -1.61733 1.53 Down NM_031190 Phosphoglycerate kinase 2 (Pgk2), mRNA -1.763395 -1.1479 1.53 Up NM_013675 Spectrin beta 1 (Spnb1), mRNA ENSMUST00000 -1.101635 -0.48714 1.53 Up 046522 Transcribed locus chr1:58443698- -1.110795 -1.72071 1.53 Down 58449898_F chr1:58443698-58449898_F chr13:97700327- -1.31913 -0.709095 1.53 Up 97700876_F chr13:97700327-97700876_F Transcribed locus, strongly similar to NP_061225.2 -0.89758 -0.287285 1.53 Up AK016384 plasma glutamate carboxypeptidase [Mus musculus] Connector enhancer of kinase suppressor of Ras 1 -1.505245 -0.888255 1.53 Up NM_001081047 (Cnksr1), mRNA -1.381555 -1.993325 1.53 Down NM_001198565 Sulf1 chr2:25774411- -1.113195 -0.503045 1.53 Up 25783736_F chr2:25774411-25783736_F chr19:44653017- -0.720335 -1.33268 1.53 Down 44654777_F chr19:44653017-44654777_F -1.80528 -1.18965 1.53 Up NM_201639 CDNA clone IMAGE:40099060 chr15:60656586- -1.718725 -1.10287 1.53 Up 60685333_R chr15:60656586-60685333_R chr15:85412264- -0.940265 -0.32897 1.53 Up 85549139_R chr15:85412264-85549139_R chr12:74135916- -0.10154 -0.71298 1.53 Down 74142780_F chr12:74135916-74142780_F -0.232105 -0.84594 1.53 Down NR_003959 Aldoart2 -0.707525 -0.08949 1.53 Up NM_001011778 Olfactory receptor 285 (Olfr285), mRNA chr17:8719950- -1.28906 -0.6744 1.53 Up 8783850_F chr17:8719950-8783850_F -1.10551 -0.4949 1.53 Up NM_013722 Strain ILS SYN3 PREDICTED: Mus musculus RIKEN cDNA -1.87156 -1.25909 1.53 Up AK086985 E030018B13 gene (E030018B13Rik), mRNA Lymphocyte antigen 6 complex, locus D, mRNA -0.324945 -0.934775 1.53 Down NM_010742 (cDNA clone MGC:36061 IMAGE:4914126) Myosin, heavy chain 7B, cardiac muscle, beta -0.97803 -0.368225 1.53 Up NAP005855-001 (Myh7b), mRNA -0.88644 -0.275795 1.53 Up NM_146734 Olfactory receptor 478 (Olfr478), mRNA -1.336925 -0.719285 1.53 Up NR_033566 AI507597 -0.16931 -0.78141 1.53 Down AW491098 Transcribed locus -0.673095 -0.05795 1.53 Up AK135304 AK135304 ENSMUST00000 Predicted gene, OTTMUSG00000008911, mRNA -0.551425 0.06459 1.53 Up 066241 (cDNA clone MGC:183810 IMAGE:9087810) 0.61407 1.22665 1.53 Up XM_001001941 Gm6436 0.76847 0.15123 1.53 Down NM_027763 Trem-like transcript protein 0.624865 1.23609 1.53 Up NM_008528 B-cell linker (Blnk), mRNA Family with sequence similarity 161, member B, mRNA (cDNA clone MGC:69959 0.50793 -0.10278 1.53 Down NM_172581 IMAGE:6509090) chr11:69184157- 0.85642 1.465595 1.53 Up 69201732_F chr11:69184157-69201732_F 0.085965 0.702145 1.53 Up NM_001081243 Filamin A interacting protein 1 (Filip1), mRNA 0.39263 -0.225005 1.53 Down NM_001099635 Myosin heavy chain mRNA, 3 flank chr1:163527603- 2.544755 3.153725 1.53 Up 163527999_F chr1:163527603-163527999_F 0.82295 1.43781 1.53 Up NR_003639 1700013N18Rik Erbb2 interacting protein, mRNA (cDNA clone 0.860755 0.245845 1.53 Down A_55_P1987847 IMAGE:4988135) LIM and senescent cell antigen like domains 2 0.42965 -0.18279 1.53 Down NM_144862 (Lims2), mRNA Cyclin dependent kinase 5 regulatory subunit 1.072445 0.455595 1.53 Down NM_009871 (Cdk5a) ENSMUST00000 Complement component 1, s subcomponent (C1s), 1.39105 0.77964 1.53 Down 087056 transcript variant 1, mRNA Rho GTPase activating protein 20, mRNA (cDNA 2.01671 1.405585 1.53 Down NM_175535 clone IMAGE:5363167) chr4:131738732- 0.580655 1.19418 1.53 Up 131739264_F chr4:131738732-131739264_F chr4:59264275- 0.78376 1.39257 1.53 Up 59287850_R chr4:59264275-59287850_R Catenin (cadherin associated protein), delta 1 2.871145 2.26081 1.53 Down NM_007615 (Ctnnd1), transcript variant 1, mRNA 2.66631 2.05036 1.53 Down NM_001013756 Grainyhead-like 3 (Drosophila) (Grhl3), mRNA Transformation related protein 53 binding protein 1, mRNA (cDNA clone MGC:30704 1.869995 1.254825 1.53 Down NM_013735 IMAGE:3979746) 2.21591 2.828505 1.53 Up NM_001101606 Predicted gene, EG667794 (EG667794), mRNA 2.026795 1.40894 1.53 Down BC057651 BC057651 TRAF-interacting protein, mRNA (cDNA clone 1.99414 2.606585 1.53 Up NM_011634 MGC:13919 IMAGE:3990371) 3.151955 2.53769 1.53 Down TC1703733 TC1703733 Transcribed locus, strongly similar to ENSMUST00000 XP_001478886.1 PREDICTED: hypothetical protein 1.75537 1.144625 1.53 Down 033479 [Mus musculus] Kelch domain containing 6 (Klhdc6), transcript 1.042245 0.431425 1.53 Down NAP098153-001 variant 2, mRNA chr17:6806387- 0.14456 -0.46533 1.53 Down 6812243_F chr17:6806387-6812243_F Echinoderm microtubule associated protein like 5, 1.19747 0.584045 1.53 Down NM_001081191 mRNA (cDNA clone IMAGE:4953665) 6.90459 7.520585 1.53 Up NM_144899 ADAMTS-like 4 (Adamtsl4), mRNA Sulfotransferase family 4A, member 1 (Sult4a1), 2.22102 1.607405 1.53 Down NM_013873 mRNA 2.568995 1.951315 1.53 Down NM_015808 Keratin associated protein 5-1 (Krtap5-1), mRNA RAB7, member RAS oncogene family (Rab7), 2.01661 1.40714 1.53 Down A_55_P2080902 mRNA Neuregulin 4, mRNA (cDNA clone 1.63372 1.023425 1.53 Down NM_032002 IMAGE:1265836) Basic leucine zipper transcription factor, ATF-like 3, mRNA (cDNA clone MGC:151460 7.61384 8.225885 1.53 Up NM_030060 IMAGE:40126402) Transcribed locus, strongly similar to NP_034645.2 4.85634 4.24503 1.53 Down AK032756 insulin-like growth factor 2 receptor [Mus musculus] chr11:95627874- 3.479395 4.091965 1.53 Up 95640824_F chr11:95627874-95640824_F 3.587855 2.97688 1.53 Down NM_001164220 Trim13 Acyl-CoA synthetase family member 3, mRNA 3.1913 2.581505 1.53 Down A_55_P2037538 (cDNA clone IMAGE:4486614) Potassium channel, subfamily K, member 5 (Kcnk5), 4.56434 5.174935 1.53 Up NM_021542 mRNA Cysteine-rich with EGF-like domains 1, mRNA 4.11231 3.50213 1.53 Down NM_133930 (cDNA clone MGC:36401 IMAGE:5310111) chr13:104591573 2.388635 1.77677 1.53 Down -104599048_R chr13:104591573-104599048_R LPS-responsive beige-like anchor (Lrba), transcript 1.856255 1.242175 1.53 Down NM_030695 variant 1, mRNA 6.44764 5.833085 1.53 Down NM_001161338 Sh3bp5l RIKEN cDNA 2310076L09 gene (2310076L09Rik), 3.318315 2.700555 1.53 Down A_55_P2104289 transcript variant 1, mRNA Elongation protein 4 homolog (S. cerevisiae) (Elp4), 3.56914 2.95515 1.53 Down NM_023876 mRNA 7.62974 7.014935 1.53 Down NM_028607 Bloc1s2 RIKEN cDNA 1700025G04 gene, mRNA (cDNA 2.536295 1.92191 1.53 Down NM_197990 clone MGC:28137 IMAGE:3981517) RIKEN cDNA 9630033F20 gene, mRNA (cDNA 4.37052 3.755755 1.53 Down NM_177003 clone MGC:182863 IMAGE:9087477) 7.48534 6.874585 1.53 Down NR_029468 Snhg12 Hook homolog 2 (Drosophila), mRNA (cDNA clone 7.63339 7.015835 1.53 Down NM_133255 IMAGE:4976545) Glutamyl-tRNA(Gln) amidotransferase, subunit C homolog (bacterial), mRNA (cDNA clone 2.16126 1.546 1.53 Down NM_029645 MGC:28449 IMAGE:4158979) RUN and SH3 domain containing 2, mRNA (cDNA 4.014245 3.405255 1.53 Down A_55_P2124183 clone IMAGE:5357662) Dual-specificity tyrosine-(Y)-phosphorylation 3.170385 2.55972 1.53 Down AK149371 regulated kinase 2 (Dyrk2), mRNA 2.678225 2.0612 1.53 Down NM_001080776 CLSP mRNA for CAR-like soluble protein 3.75382 3.140275 1.53 Down NM_145587 SH3-binding kinase 1 (Sbk1), mRNA Rho GTPase activating protein 18, mRNA (cDNA 5.17369 5.791135 1.53 Up NM_176837 clone MGC:31193 IMAGE:4194996) Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4, mRNA (cDNA 2.644665 2.02799 1.53 Down NM_001037812 clone MGC:182410 IMAGE:9056304) CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 (Ctdsp2), 3.315735 2.699945 1.53 Down NM_146012 transcript variant b, mRNA chr8:41475940- 2.05162 1.441645 1.53 Down 41476460_F chr8:41475940-41476460_F 2.543735 3.154535 1.53 Up NAP060965-1 Copine V (Cpne5), mRNA RWD domain containing 3, mRNA (cDNA clone 2.178645 1.56244 1.53 Down NM_028456 IMAGE:1513356) chr2:67411703- 0.972765 0.35902 1.53 Down 67412293_F chr2:67411703-67412293_F NHL repeat containing 1, mRNA (cDNA clone 2.652065 2.035075 1.53 Down NM_175340 MGC:143773 IMAGE:40093176) 7.47519 6.861285 1.53 Down NM_026984 Mll5 Signal transducer and activator of transcription 1, 3.354035 2.742445 1.53 Down NM_009283 mRNA (cDNA clone MGC:6411 IMAGE:3587831) Epoxide hydrolase 1, microsomal, mRNA (cDNA 5.19274 4.577135 1.53 Down NAP111601-1 clone MGC:30577 IMAGE:3491966) RIKEN cDNA 1810048J11 gene (1810048J11Rik), 1.88891 1.27167 1.53 Down NM_026327 mRNA Threonyl-tRNA synthetase-like 2, mRNA (cDNA 4.21785 3.6029 1.53 Down NM_172310 clone MGC:31414 IMAGE:4458085) Regulation of nuclear pre-mRNA domain containing 1B, mRNA (cDNA clone MGC:36579 3.67228 3.054275 1.53 Down NM_027434 IMAGE:5100766) ATPase, H+ transporting, lysosomal V1 subunit A, 5.72049 5.107785 1.53 Down NM_007508 mRNA (cDNA clone MGC:6531 IMAGE:2651677) Killer cell lectin-like receptor subfamily A, member 3.710485 3.09573 1.53 Down A_55_P1998023 12 (Klra12), mRNA Splicing factor 3a, subunit 1, mRNA (cDNA clone 7.44334 6.832135 1.53 Down NM_026175 MGC:6887 IMAGE:2651773) 9.13249 8.520985 1.53 Down NAP111391-1 NAP111391-1 Thioredoxin 2 (Txn2), nuclear gene encoding 8.74669 8.135835 1.53 Down NM_019913 mitochondrial protein, mRNA Rho, GDP dissociation inhibitor (GDI) beta, mRNA 10.52204 9.907235 1.53 Down NM_007486 (cDNA clone MGC:25396 IMAGE:4923219) V-ral simian leukemia viral oncogene homolog A (ras related), mRNA (cDNA clone MGC:25671 2.361795 1.74856 1.53 Down NM_019491 IMAGE:4501311) Zinc finger CCCH type containing 12D, mRNA 7.78819 7.172585 1.53 Down NM_172785 (cDNA clone MGC:132956 IMAGE:40062049) ADP-ribosylation factor-like 6, mRNA (cDNA clone 2.325245 1.710645 1.53 Down NM_019665 MGC:27826 IMAGE:3484868) KDEL (Lys-Asp-Glu-Leu) containing 1, mRNA 3.128705 2.518285 1.53 Down NM_023645 (cDNA clone MGC:28356 IMAGE:4018698) Mitochondrial ribosomal protein L50, mRNA 3.68286 3.069545 1.53 Down NM_178603 (cDNA clone MGC:29213 IMAGE:5035369) chr10:96098058- 7.01539 6.399735 1.53 Down 96098623_F chr10:96098058-96098623_F Eukaryotic translation initiation factor 4E member 3, mRNA (cDNA clone MGC:35709 4.91754 4.307885 1.53 Down NM_025829 IMAGE:5369891) Zinc finger and BTB domain containing 20, mRNA 4.66999 4.060435 1.53 Down NM_019778 (cDNA clone MGC:35911 IMAGE:4971586) RAS protein activator like 2, mRNA (cDNA clone -1.25761 -1.864605 1.52 Down NM_177644 MGC:141546 IMAGE:40086771) -1.147795 -1.753495 1.52 Down TC1661180 TC1661180 Potassium channel, subfamily K, member 12, mRNA -0.459355 -1.068125 1.52 Down NM_199251 (cDNA clone MGC:169757 IMAGE:8861152) Solute carrier family 12, member 1, mRNA (cDNA -1.364265 -0.755785 1.52 Up A_55_P2373515 clone MGC:18410 IMAGE:4236020) -1.27117 -1.872055 1.52 Down AK051100 CDNA clone IMAGE:30294555 chr8:49858771- -0.95724 -1.55774 1.52 Down 49859010_R chr8:49858771-49859010_R chr3:126989696- -1.644535 -1.043095 1.52 Up 127112471_F chr3:126989696-127112471_F Guanine nucleotide binding protein, alpha ENSMUST00000 transducing 2, mRNA (cDNA clone MGC:28985 -1.825205 -2.43324 1.52 Down 107860 IMAGE:4506728) -1.19073 -1.79144 1.52 Down NM_177396 Interferon-lambda3 (Ifnl3) -1.39022 -1.994675 1.52 Down NM_010204 Fibroblast growth factor (Fgf6) mRNA, 3 end chr5:108544188- -1.51505 -0.906735 1.52 Up 108545013_F chr5:108544188-108545013_F chr14:62267786- -0.853685 -1.459825 1.52 Down 62285335_F chr14:62267786-62285335_F Parotid secretory protein, mRNA (cDNA clone -1.7597 -1.15257 1.52 Up NM_008953 MGC:11605 IMAGE:2616413) chr2:71575871- -1.29951 -1.90735 1.52 Down 71583454_R chr2:71575871-71583454_R Glucosaminyl (N-acetyl) transferase 3, mucin type -1.09594 -1.700865 1.52 Down NM_028087 (Gcnt3), mRNA chr17:29383810- -1.04414 -0.44175 1.52 Up 29384205_F chr17:29383810-29384205_F chr4:54669012- -1.094785 -0.490575 1.52 Up 54940960_R chr4:54669012-54940960_R chr10:72726649- -1.05727 -1.66547 1.52 Down 72799726_F chr10:72726649-72799726_F -0.763115 -0.161605 1.52 Up NM_009903 Claudin 4 (Cldn4), mRNA -0.84777 -0.24149 1.52 Up lincP21 lincP21 Kelch repeat and BTB (POZ) domain containing 5, mRNA (cDNA clone MGC:169513 -1.81283 -2.41948 1.52 Down NM_028202 IMAGE:8860908) chr3:148884650- -1.220705 -0.61466 1.52 Up 148888709_R chr3:148884650-148888709_R chr9:37071677- -1.17782 -1.781605 1.52 Down 37072244_R chr9:37071677-37072244_R Vanin 1, mRNA (cDNA clone MGC:29064 -1.26259 -0.66261 1.52 Up NM_011704 IMAGE:5041670) Small nuclear ribonucleoprotein N, mRNA (cDNA -0.82746 -1.43159 1.52 Down NM_013670 clone MGC:18604 IMAGE:3987218) -1.62082 -1.01452 1.52 Up AK050221 Transcribed locus Mus musculus, SH3 domain protein D19, clone -0.5204 0.08335 1.52 Up NM_001082414 IMAGE:4158640, mRNA -0.55882 -1.164575 1.52 Down XM_003086064 LOC100039183 chr1:87343550- -1.148765 -1.75476 1.52 Down 87362900_R chr1:87343550-87362900_R Solute carrier family 44, member 1 (Slc44a1), -0.047715 -0.649195 1.52 Down AK164818 mRNA -1.238665 -1.846395 1.52 Down AK016046 Transcribed locus -1.069645 -1.678345 1.52 Down chr8:49853937- chr8:49853937-49874087_R 49874087_R chr12:53669892- -1.76929 -1.168865 1.52 Up 53710742_F chr12:53669892-53710742_F Phosphodiesterase 3A, cGMP inhibited (Pde3a), -0.817635 -0.21279 1.52 Up NM_018779 mRNA -1.096185 -0.491935 1.52 Up NR_033501 Gm7271 chr7:6302922- -0.49196 -1.10013 1.52 Down 6306477_F chr7:6302922-6306477_F chr17:88993214- -1.40284 -0.794565 1.52 Up 89025839_F chr17:88993214-89025839_F BCL2-associated X protein, mRNA (cDNA clone -1.691245 -1.08282 1.52 Up A_55_P2137416 MGC:11739 IMAGE:3968903) ENSMUST00000 -1.42363 -0.821465 1.52 Up 105102 ENSMUST00000105102 -1.40194 -0.796425 1.52 Up NM_032542 SLP-M -0.872385 -0.267625 1.52 Up AK003710 Transcribed locus chr18:77291264- -1.395765 -0.78699 1.52 Up 77299664_F chr18:77291264-77299664_F Rous sarcoma oncogene (Src), transcript variant 1, -0.740945 -0.13752 1.52 Up NM_009271 mRNA chr17:32035750- -1.29255 -0.68966 1.52 Up 32056000_R chr17:32035750-32056000_R Solute carrier family 22 (organic cation transporter), member 1, mRNA (cDNA clone MGC:14019 -0.25422 -0.86236 1.52 Down NM_009202 IMAGE:4211979) chr3:145313275- -0.852615 -0.25124 1.52 Up 145315057_F chr3:145313275-145315057_F chr11:95097483- -0.930105 -0.32971 1.52 Up 95097918_F chr11:95097483-95097918_F ENSMUST00000 RIKEN cDNA 4921520G13 gene (4921520G13Rik), -0.37282 -0.977575 1.52 Down 154147 mRNA 0.31735 -0.283965 1.52 Down NM_030101 Pgpep1l chr1:69531191- 0.223385 0.825545 1.52 Up 69570566_R chr1:69531191-69570566_R chr18:36472370- 0.800215 1.403445 1.52 Up 36472659_F chr18:36472370-36472659_F 0.489925 1.09237 1.52 Up NM_008022 Forkhead box D4 (Foxd4), mRNA chr15:34078479- 0.6697 1.277045 1.52 Up 34079439_F chr15:34078479-34079439_F 0.21303 0.81409 1.52 Up NM_001033276 Mll2 chr17:87483814- 0.91619 1.519925 1.52 Up 87493039_F chr17:87483814-87493039_F Histone H4 transcription factor, mRNA (cDNA 0.161945 0.76965 1.52 Up NM_172162 clone MGC:27746 IMAGE:2651006) 0.934145 1.542245 1.52 Up NM_010859 Ventricular alkali myosin light chain chrX:75813213- 0.47455 1.074065 1.52 Up 75829323_F chrX:75813213-75829323_F 0.95792 0.349595 1.52 Down NRON NRON chr18:12755615- 1.57076 2.17664 1.52 Up 12773365_F chr18:12755615-12773365_F chr17:24152225- 0.82723 0.22335 1.52 Down 24169870_R chr17:24152225-24169870_R 1.08622 1.689085 1.52 Up NM_181848 Optineurin (Optn) 1.39861 2.006685 1.52 Up NM_001104615 Vomeronasal 2, receptor 4 (Vmn2r4), mRNA chr19:23254618- 0.351315 0.95167 1.52 Up 23268776_R chr19:23254618-23268776_R chr2:119412770- 0.914625 0.30949 1.52 Down 119435110_R chr2:119412770-119435110_R 0.95887 0.35626 1.52 Down XR_033994 Gm9519 chr11:95644899- 1.389865 0.79009 1.52 Down 95658549_F chr11:95644899-95658549_F 0.21288 -0.390845 1.52 Down NM_007735 Alpha 4 collagen IV (Col4a4) Zinc finger, CCHC domain containing 18 (Zcchc18), 1.789285 1.18081 1.52 Down NM_001035510 transcript variant 3, mRNA chr13:98062189- 2.243915 1.63669 1.52 Down 98066613_F chr13:98062189-98066613_F PREDICTED: Mus musculus similar to Chain A, Crystal Structure Of Glia Maturation Factor-Gamma 2.57548 1.97284 1.52 Down A_55_P1964459 (Gmfg) From Mus Musculus At 1.5 chr19:60269158- 2.06638 1.46381 1.52 Down 60272919_R chr19:60269158-60272919_R Protein phosphatase 1, regulatory subunit 3D 3.05584 2.447405 1.52 Down NM_001085501 (Ppp1r3d), mRNA 2.898465 2.29737 1.52 Down NM_027974 Efhc1 4.104945 3.501015 1.52 Down NM_023141 Torsin family 3, member A (Tor3a), mRNA 4.29864 3.693005 1.52 Down NM_015772 Sal-like 2 (Drosophila) (Sall2), mRNA DnaJ (Hsp40) homolog, subfamily C, member 10, mRNA (cDNA clone MGC:28281 3.0376 2.437725 1.52 Down NM_024181 IMAGE:4010341) Adaptor-related protein complex 2, beta 1 subunit 4.578045 3.975475 1.52 Down NM_001035854 (Ap2b1), transcript variant 2, mRNA 4.38354 3.78035 1.52 Down NM_010630 Kinesin family member C2 (Kifc2), mRNA 0.38813 -0.21672 1.52 Down NM_011066 Period homolog 2 (Drosophila) (Per2), mRNA 2.687245 2.082095 1.52 Down NM_018825 SH2B adaptor protein 2 (Sh2b2), mRNA Microphthalmia-associated transcription factor 2.446065 1.84417 1.52 Down NM_001113198 (Mitf), transcript variant 2, mRNA 2.920105 2.31342 1.52 Down NP065022 NP065022 Cellular retinoic acid binding protein I (Crabp1), 8.13304 8.732385 1.52 Up NAP111074-1 mRNA 4.40307 3.803395 1.52 Down NM_007657 CD9 antigen (Cd9), mRNA Zinc finger protein 689, mRNA (cDNA clone 4.80804 4.199865 1.52 Down NM_175163 IMAGE:1329526) Methylenetetrahydrofolate dehydrogenase (NADP+ 2.370925 1.76572 1.52 Down NM_026788 dependent) 2-like (Mthfd2l), mRNA 3.979995 3.37957 1.52 Down chr14:44292637- chr14:44292637-44293014_F 44293014_F RIKEN cDNA C430048L16 gene, mRNA (cDNA 4.51739 3.91401 1.52 Down NM_198957 clone IMAGE:5150022) Ubiquitin specific peptidase 30, mRNA (cDNA 6.29554 5.691385 1.52 Down NM_001033202 clone IMAGE:4911968) YdjC homolog (bacterial), mRNA (cDNA clone 6.77324 6.169185 1.52 Down NM_026940 MGC:144469 IMAGE:40102346) 7.95724 7.349885 1.52 Down NM_007754 Carboxypeptidase D (Cpd), mRNA Glucosamine-6-phosphate deaminase 2, mRNA 4.84119 4.23862 1.52 Down NM_001038015 (cDNA clone MGC:8283 IMAGE:3593102) Thioredoxin interacting protein, mRNA (cDNA 8.03624 7.429535 1.52 Down NM_001009935 clone MGC:25534 IMAGE:3591421) 5.72759 5.126585 1.52 Down XM_286185 Gm5093 chr2:60038543- 2.727495 2.126535 1.52 Down 60046318_R chr2:60038543-60046318_R Carbohydrate kinase domain containing (Carkd), 7.21669 6.613185 1.52 Down NM_026995 mRNA DIP2 disco-interacting protein 2 homolog C (Drosophila), mRNA (cDNA clone MGC:178466 2.7638 2.155475 1.52 Down NM_001081426 IMAGE:9053458) 5.31284 4.708685 1.52 Down NM_009982 Cathepsin C (Ctsc), mRNA 7.85664 7.253285 1.52 Down NM_001166597 Dgkz 9.45964 8.855485 1.52 Down NM_012015 MacroH2A1.2 Slingshot homolog 2 (Drosophila), mRNA (cDNA 4.076265 3.470925 1.52 Down NM_177710 clone MGC:176354 IMAGE:9056005) 3.25226 3.85462 1.52 Up NM_011667 Ubiquitin-activating enzyme E1 (Ube1y1) Leucine rich repeat containing 27 (Lrrc27), transcript 7.04209 6.437835 1.52 Down A_55_P2170105 variant 2, mRNA 4.21678 3.613395 1.52 Down NM_152823 Unc-5 homolog C (C. elegans)-like (Unc5cl), mRNA Transcription elongation factor B (SIII), polypeptide 10.20994 9.604635 1.52 Down NM_026305 2 (Tceb2), mRNA SET and MYND domain containing 2, mRNA 8.40644 7.801685 1.52 Down NM_026796 (cDNA clone MGC:28724 IMAGE:4458755) PREDICTED: Mus musculus Ras association ENSMUST00000 (RalGDS/AF-6) and pleckstrin homology domains 1 -1.879655 -1.289655 1.51 Up 127573 (Raph1), mRNA chr13:112717680 -1.138745 -1.728985 1.51 Down -112733330_F chr13:112717680-112733330_F chr11:97275905- -1.704845 -1.108545 1.51 Up 97310538_F chr11:97275905-97310538_F -1.768775 -1.174095 1.51 Up NM_133256 Genomic screen homeobox protein 2 (Gsh-2) Single-stranded DNA binding protein 2 (Ssbp2), -0.764715 -0.166765 1.51 Up A_55_P2155056 transcript variant 2, mRNA -0.934235 -0.34212 1.51 Up NM_001033260 Storkhead box 1 (Stox1), mRNA -0.39696 -0.995785 1.51 Down NM_001081242 Talin 2, mRNA (cDNA clone IMAGE:3986099) Uridine phosphorylase 2, mRNA (cDNA clone -1.130315 -1.723715 1.51 Down NAP114173-1 MGC:28547 IMAGE:4196835) -1.318015 -1.91154 1.51 Down XR_106095 Gm10535 -1.492505 -0.898195 1.51 Up XR_105495 Gm8075 CAMP responsive element modulator, mRNA -1.307325 -0.714555 1.51 Up NM_001110851 (cDNA clone IMAGE:3373396) chr8:114477602- -0.802285 -0.21251 1.51 Up 114488627_F chr8:114477602-114488627_F chr4:118723941- -0.79407 -1.38587 1.51 Down 118757032_R chr4:118723941-118757032_R Spinster homolog 3 (Drosophila), mRNA (cDNA -0.872545 -0.281055 1.51 Up NM_029932 clone MGC:183689 IMAGE:9087689) chr3:95443575- -1.05224 -1.64557 1.51 Down 95462543_F chr3:95443575-95462543_F -0.264555 0.327065 1.51 Up NM_013681 Synapsin II (Syn2), transcript variant IIb, mRNA ENSMUST00000 -1.3073 -0.716615 1.51 Up 103637 ENSMUST00000103637 chr11:53592946- -0.850645 -1.441695 1.51 Down 53637922_F chr11:53592946-53637922_F chr1:138546641- -1.223155 -0.63114 1.51 Up 138558591_R chr1:138546641-138558591_R Butyrophilin-like 9, mRNA (cDNA clone -1.5021 -0.911595 1.51 Up AY177687 MGC:183719 IMAGE:9087719) Potassium channel tetramerisation domain containing 19, mRNA (cDNA clone MGC:159134 -1.637465 -1.043295 1.51 Up NM_177791 IMAGE:40129946) chr1:183783306- -1.16454 -0.571505 1.51 Up 183834531_R chr1:183783306-183834531_R RIKEN cDNA 9030409G11 gene (9030409G11Rik), -0.78227 -1.37793 1.51 Down NM_144531 transcript variant 1, mRNA Transcribed locus, strongly similar to XP_001476487.1 PREDICTED: hypothetical protein -0.668895 -0.07546 1.51 Up AK154753 [Mus musculus] -1.272715 -0.674085 1.51 Up XR_001621 1700084M14Rik Potassium voltage-gated channel, shaker-related ENSMUST00000 subfamily, beta member 3, mRNA (cDNA clone -0.155865 0.441095 1.51 Up 142279 MGC:27635 IMAGE:4507029) chr10:116401772 -0.743535 -1.336645 1.51 Down -116404452_F chr10:116401772-116404452_F Bone gamma carboxyglutamate protein 1 (Bglap1), -1.67415 -1.07773 1.51 Up NM_001037939 transcript variant 1, mRNA GDP-L-fucose:beta-D-galactoside 2-alpha-L- -1.549515 -0.95415 1.51 Up NM_008051 fucosyltransferase FUT-I chr9:67414463- -0.544015 -1.13602 1.51 Down 67483185_R chr9:67414463-67483185_R ELK4, member of ETS oncogene family (Elk4), -1.18933 -0.598795 1.51 Up A_55_P2021341 mRNA chr4:11926618- -1.174075 -0.57541 1.51 Up 11936190_R chr4:11926618-11936190_R chr14:72400656- -1.448005 -0.85537 1.51 Up 72400887_F chr14:72400656-72400887_F -0.936575 -0.339915 1.51 Up NM_134234 Vomeronasal 1 receptor, G12 (V1rg12), mRNA chr14:27176652- -0.823015 -0.230745 1.51 Up 27227602_F chr14:27176652-27227602_F chr7:6210340- -1.09261 -0.5002 1.51 Up 6229115_F chr7:6210340-6229115_F -0.81234 -1.41016 1.51 Down XM_003086593 F830223B06Rik Exonuclease 3-5 domain-like 1, mRNA (cDNA 0.157885 0.74944 1.51 Up NM_172857 clone MGC:178306 IMAGE:9053298) ENSMUST00000 0.2268 0.822825 1.51 Up 103590 CDNA sequence BC080695 (BC080695), mRNA Dynamin binding protein, mRNA (cDNA clone 0.137275 0.72866 1.51 Up NM_028029 IMAGE:5135276) chr11:55315017- 0.20648 -0.38389 1.51 Down 55322092_R chr11:55315017-55322092_R Solute carrier family 27 (fatty acid transporter), ENSMUST00000 member 5, mRNA (cDNA clone MGC:13926 0.04809 -0.549515 1.51 Down 095076 IMAGE:4193807) chr13:94069868- 0.79721 1.39265 1.51 Up 94070007_R chr13:94069868-94070007_R 0.855805 0.260855 1.51 Down NM_001004176 Mastermind like 3 (Drosophila) (Maml3), mRNA Cysteine-rich perinuclear theca 4, mRNA (cDNA 0.985255 0.38603 1.51 Down NM_173412 clone MGC:182888 IMAGE:9087502) Polo-like kinase 5 (Drosophila), mRNA (cDNA 1.422435 0.82779 1.51 Down NM_183152 clone MGC:113809 IMAGE:30679265) Asparaginase homolog (S. cerevisiae) (Aspg), 0.714 1.307165 1.51 Up NM_001081169 mRNA Colony stimulating factor 1 (macrophage), mRNA 0.95906 0.36541 1.51 Down A_55_P2169694 (cDNA clone IMAGE:5342906) chr14:77006215- 1.632525 2.2252 1.51 Up 77063293_R chr14:77006215-77063293_R 0.924955 0.328215 1.51 Down XM_003086823 LOC634012 RIKEN cDNA 1190005I06 gene, mRNA (cDNA 3.660975 4.25743 1.51 Up NM_197988 clone MGC:41566 IMAGE:1245153) 1.86777 2.461575 1.51 Up AK137058 Centrosomal protein 63 (Cep63), mRNA Leucine rich repeat containing 16A, mRNA (cDNA 1.314575 0.7193 1.51 Down NM_026825 clone IMAGE:4014128) chr10:81684904- 1.4315 0.83936 1.51 Down 81685501_R chr10:81684904-81685501_R 3.707935 3.10913 1.51 Down NM_146694 Olfactory receptor 1466 (Olfr1466), mRNA Ets variant gene 1, mRNA (cDNA clone MGC:6207 1.72051 1.122435 1.51 Down NM_007960 IMAGE:3257346) ENSMUST00000 RIKEN cDNA C730048C13 gene, mRNA (cDNA 0.81438 1.40518 1.51 Up 143967 clone MGC:163967 IMAGE:40130613) AU RNA binding protein/enoyl-coenzyme A 1.4402 2.032115 1.51 Up AK169661 hydratase, mRNA (cDNA clone IMAGE:4924434) Yippee-like 4 (Drosophila), mRNA (cDNA clone 1.609545 1.016095 1.51 Down NM_001005342 MGC:155579 IMAGE:8734012) Non imprinted in Prader-Willi/Angelman syndrome 3.76121 3.16347 1.51 Down NM_153578 1 homolog (human) (Nipa1), mRNA 2.843015 2.251265 1.51 Down NM_008883 Plexin A3 (Plxna3), mRNA DNA (cytosine-5-)-methyltransferase 3-like 0.0941 -0.49828 1.51 Down NM_019448 (Dnmt3l), transcript variant 1, mRNA 5.85644 5.265185 1.51 Down NM_001163015 Gprasp2 RIKEN cDNA 3110001K24 gene, mRNA (cDNA 3.24424 2.65132 1.51 Down NM_029389 clone IMAGE:9053370) ELOVL family member 7, elongation of long chain 2.054455 1.455585 1.51 Down NM_029001 fatty acids (yeast) (Elovl7), mRNA Toll-like receptor 2, mRNA (cDNA clone 2.312545 1.71345 1.51 Down NM_011905 MGC:11394 IMAGE:3966249) 4.58069 5.173685 1.51 Up NM_001168500 A330049M08Rik 2.33083 1.735075 1.51 Down NM_010283 Alpha-1,3-galactosyltransferase gene chr17:35080914- 3.55249 2.959975 1.51 Down 35090009_F chr17:35080914-35090009_F SLAM family member 6, mRNA (cDNA clone 4.66348 4.06475 1.51 Down NM_030710 MGC:41003 IMAGE:1225313) CAS1 domain containing 1, mRNA (cDNA clone 3.928095 3.33349 1.51 Down NM_145398 IMAGE:2649724) 2.755895 2.165415 1.51 Down NM_178404 MKIAA2035 protein Domesticus laminet-1A (Lmnt1) mRNA, complete 3.58724 2.994305 1.51 Down NAP111601-1 cds; alternatively spliced Dual-specificity tyrosine-(Y)-phosphorylation 3.49462 2.900235 1.51 Down NM_001014390 regulated kinase 2 (Dyrk2), mRNA Tripartite motif protein 37, mRNA (cDNA clone 2.164115 1.57252 1.51 Down NM_197987 IMAGE:5067215) Disabled homolog 2 (Drosophila) interacting protein 4.225615 4.815835 1.51 Up NM_001114125 (Dab2ip), transcript variant 2, mRNA chr3:19211659- 2.001085 1.40939 1.51 Down 19213735_F chr3:19211659-19213735_F T-cell specific GTPase, mRNA (cDNA clone 9.65199 9.058785 1.51 Down NM_001145164 MGC:18429 IMAGE:3662733) chr18:6201019- 1.254435 0.65635 1.51 Down 6201758_R chr18:6201019-6201758_R Solute carrier organic anion transporter family, ENSMUST00000 member 2b1, mRNA (cDNA clone 4.99824 4.40092 1.51 Down 131841 IMAGE:5133329) chr11:95627874- 6.22949 6.826135 1.51 Up 95640824_F chr11:95627874-95640824_F ENSMUST00000 Stromal antigen 2 (Stag2), transcript variant 1, 5.31434 4.718585 1.51 Down 076889 mRNA 6.25349 5.661485 1.51 Down NM_001190414 Gne Glycerophosphodiester phosphodiesterase domain containing 5, mRNA (cDNA clone MGC:37148 4.45574 5.052435 1.51 Up NM_201352 IMAGE:4953174) NIMA (never in mitosis gene a)-related expressed kinase 1, mRNA (cDNA clone MGC:198796 2.51249 1.91631 1.51 Down NM_175089 IMAGE:9054377) Phosphatase and actin regulator 1 isoform 4 5.92734 5.336085 1.51 Down A_55_P2068248 (Phactr1) mRNA, complete cds, alternatively spliced chr15:77164450- 6.35629 5.761235 1.51 Down 77201325_F chr15:77164450-77201325_F Prostaglandin F2 receptor negative regulator 3.31709 2.718535 1.51 Down NM_011197 (Ptgfrn), mRNA Queuine tRNA-ribosyltransferase domain containing 2.03235 1.43766 1.51 Down NM_029128 1 (Qtrtd1), mRNA chr18:6144775- 3.84967 3.25428 1.51 Down 6202105_R chr18:6144775-6202105_R 2.60428 2.006805 1.51 Down NM_029888 Zinc finger 142 [Mus musculus], mRNA sequence Fas (TNF receptor superfamily member 6) (Fas), 7.24049 6.647535 1.51 Down NM_007987 mRNA 2.97451 2.380805 1.51 Down A_55_P2040988 Neuronal PAS3 (Npas3) Calcium release-activated calcium channel 2 (Orai2 3.93308 3.33958 1.51 Down NM_178751 gene), Orai2Long isoform RIKEN cDNA A330103N21 gene, mRNA (cDNA 6.55599 5.966085 1.51 Down NM_010513 clone IMAGE:1363058) 6.37334 5.782235 1.51 Down NM_007408 C57BL/6J adipose differentiation-related protein Small nuclear ribonucleoprotein polypeptide A, 7.59554 7.005135 1.51 Down NM_015782 mRNA (cDNA clone MGC:6132 IMAGE:3483391) 4.361855 3.766315 1.51 Down NM_001162903 2010109K11Rik SEC14 and spectrin domains 1, mRNA (cDNA clone 3.85089 3.255525 1.51 Down NM_175465 IMAGE:2581948) TCDD-inducible poly(ADP-ribose) polymerase, 7.93804 7.343285 1.51 Down NM_178892 mRNA (cDNA clone IMAGE:3485144) 6.92694 6.332285 1.51 Down NM_207687 Espin (Espn), transcript variant 6, mRNA RIKEN cDNA 3300001P08 gene (3300001P08Rik), 8.61884 8.021285 1.51 Down NM_026313 mRNA 1.531735 0.93355 1.51 Down NM_027914 Bbs10 3-phosphoadenosine 5-phosphosulfate synthase 1 5.91654 5.317685 1.51 Down NM_011863 (Papss1), mRNA 5.79329 5.197285 1.51 Down NM_001162955 Gpr15 Microsomal glutathione S-transferase 3, mRNA 4.054355 3.457895 1.51 Down NM_025569 (cDNA clone MGC:35738 IMAGE:5372427) Tumor necrosis factor, alpha-induced protein 8 5.12884 4.536335 1.51 Down NM_134131 (Tnfaip8), mRNA 4.027745 3.43712 1.51 Down BB237529 Transcribed locus 2.9958 2.401125 1.51 Down NM_026574 INO80 homolog (S. cerevisiae) (Ino80), mRNA ENSMUST00000 Predicted gene, EG624866, mRNA (cDNA clone 8.04494 7.454785 1.51 Down 068342 MGC:182436 IMAGE:9056330) Heparan-alpha-glucosaminide N-acetyltransferase, mRNA (cDNA clone MGC:37875 5.53904 4.946485 1.51 Down NM_029884 IMAGE:5101064) Acyl-Coenzyme A dehydrogenase, long-chain, mRNA (cDNA clone MGC:36219 6.39879 5.804785 1.51 Down NM_007381 IMAGE:4236225) 3.14017 2.543615 1.51 Down NM_001202445 Mapk8ip1 ENSMUST00000 Zinc finger protein 182 (Zfp182), transcript variant 7.78514 8.377535 1.51 Up 082392 2, mRNA Leukocyte receptor cluster (LRC) member 1 4.96579 4.37413 1.51 Down NM_027203 (Leng1), mRNA chr10:96098058- 5.63509 5.037985 1.51 Down 96098623_F chr10:96098058-96098623_F Protein phosphatase 2, regulatory subunit B (B56), beta isoform, mRNA (cDNA clone 5.46074 4.864985 1.51 Down NM_198168 IMAGE:5007577) chr17:35080914- 4.58129 3.98663 1.51 Down 35090009_F chr17:35080914-35090009_F Attractin like 1, mRNA (cDNA clone 2.63259 2.03376 1.51 Down NM_181415 IMAGE:5354506) 7.26654 6.676185 1.51 Down NM_001170786 Mthfd1l Sigma non-opioid intracellular receptor 1, mRNA 7.26434 6.666835 1.51 Down NM_011014 (cDNA clone MGC:29924 IMAGE:5123891) chr8:26869173- -1.63367 -2.22233 1.5 Down 26869823_R chr8:26869173-26869823_R chr8:40257009- -0.54566 -1.135325 1.5 Down 40258777_F chr8:40257009-40258777_F -1.285195 -1.87475 1.5 Down NR_002872 Gm6042 chr3:58730418- -1.71549 -2.304715 1.5 Down 58742493_R chr3:58730418-58742493_R chr3:37543523- -1.27917 -1.86891 1.5 Down 37613073_R chr3:37543523-37613073_R chr14:73729977- -1.28097 -0.69512 1.5 Up 73751877_F chr14:73729977-73751877_F chr5:125190100- -1.695925 -2.28249 1.5 Down 125209625_R chr5:125190100-125209625_R chr3:90427029- -1.804475 -2.39058 1.5 Down 90427674_F chr3:90427029-90427674_F Alpha glucosidase 2 alpha neutral subunit (Ganab), -0.254435 -0.84359 1.5 Down A_55_P2048224 mRNA FXYD domain-containing ion transport regulator 4 -1.570555 -2.157295 1.5 Down NM_033648 (Fxyd4), mRNA -0.974855 -0.38922 1.5 Up NM_030742 Vomeronasal 1 receptor, D1 (V1rd1), mRNA chr14:21029450- -0.43601 0.14921 1.5 Up 21049451_F chr14:21029450-21049451_F ENSMUST00000 -1.585615 -0.999345 1.5 Up 115940 LOC100040235 PREDICTED: Mus musculus hypothetical protein -0.854915 -1.441225 1.5 Down BY456555 LOC100041809 (LOC100041809), mRNA -0.65863 -0.069955 1.5 Up NM_026334 Lipase, gastric (Lipf), mRNA ENSMUST00000 Cytochrome P450, family 2, subfamily c, -0.467625 -1.05436 1.5 Down 153759 polypeptide 54 (Cyp2c54), mRNA chr2:102082091- -1.584905 -0.997005 1.5 Up 102082751_R chr2:102082091-102082751_R -2.255445 -1.669405 1.5 Up NM_001011525 Olfactory receptor 1415 (Olfr1415), mRNA -1.80194 -1.21384 1.5 Up NM_053143 Protocadherin beta 18 (Pcdhb18), mRNA chr11:70196232- -0.25704 -0.842175 1.5 Down 70203307_R chr11:70196232-70203307_R -0.515435 -1.10441 1.5 Down NM_009392 T-cell leukemia, homeobox 2 (Tlx2), mRNA chr14:103746051 -1.070445 -0.484375 1.5 Up -103840199_F chr14:103746051-103840199_F chr8:37612672- -0.199245 0.389655 1.5 Up 37614507_R chr8:37612672-37614507_R Neuropilin (NRP) and tolloid (TLL)-like 2, mRNA -0.594505 -1.18043 1.5 Down NM_001081324 (cDNA clone MGC:198809 IMAGE:9054390) Solute carrier family 22 (organic anion transporter), member 6, mRNA (cDNA clone MGC:13982 0.46436 1.05364 1.5 Up NM_008766 IMAGE:4163278) chr16:44720170- 0.370045 0.95568 1.5 Up 44723911_R chr16:44720170-44723911_R chr19:4996544- 1.251385 1.837735 1.5 Up 4997119_R chr19:4996544-4997119_R 1.13633 1.72284 1.5 Up A_55_P2146789 Ropporin 1-like (Ropn1l), mRNA chr10:81680941- 1.09797 0.511875 1.5 Down 81704964_R chr10:81680941-81704964_R Mitogen-activated protein kinase 1, mRNA (cDNA 6.09189 5.50625 1.5 Down NM_011949 clone IMAGE:3584356) chr6:47687025- 0.876585 0.28988 1.5 Down 47728525_F chr6:47687025-47728525_F ENSMUST00000 Proline-rich protein MP5, mRNA (cDNA clone 1.108145 1.6932 1.5 Up 146581 MGC:117856 IMAGE:4191067) 0.2521 -0.33303 1.5 Down NM_153596 Transmembrane protein 17 (Tmem17), mRNA chr2:38830900- 3.10916 3.69553 1.5 Up 38841225_R chr2:38830900-38841225_R Basic helix-loop-helix family, member a15, mRNA 2.53279 3.12112 1.5 Up NM_010800 (cDNA clone MGC:19046 IMAGE:4189225) Aatyk3 mRNA for apoptosis-associated tyrosine 4.13895 3.55376 1.5 Down NM_001005511 kinase 3 RIKEN cDNA 1810009N02 gene (1810009N02Rik), 5.78879 6.373985 1.5 Up A_55_P1975843 mRNA Transcribed locus, strongly similar to XP_001478886.1 PREDICTED: hypothetical protein 1.918845 1.33091 1.5 Down AK138549 [Mus musculus] chr14:103751075 3.53749 2.949005 1.5 Down -103769725_F chr14:103751075-103769725_F 7.00499 7.590435 1.5 Up NM_009778 Complement component 3 (C3), mRNA 3.2795 2.69327 1.5 Down NM_008052 Deltex1 PREDICTED: Mus musculus predicted gene, 2.95732 2.37136 1.5 Down AK164331 EG626854 (EG626854), mRNA V-crk sarcoma virus CT10 oncogene homolog (avian), mRNA (cDNA clone MGC:37330 6.01149 5.424885 1.5 Down NM_133656 IMAGE:4975654) Glutamate receptor, ionotropic, kainate 5 (gamma 2) 4.66324 4.075075 1.5 Down NM_008168 (Grik5), mRNA RIKEN cDNA 2210010B09 gene, mRNA (cDNA 1.3763 0.79069 1.5 Down NM_172919 clone MGC:170909 IMAGE:8862304) 6.36704 5.780585 1.5 Down NM_026120 RIKEN cDNA 2410127L17 gene (2410127L17Rik), mRNA RIKEN cDNA 1190005F20 gene, mRNA (cDNA 4.131985 3.545275 1.5 Down NM_026876 clone IMAGE:4459087) 4.181025 3.59323 1.5 Down AK142062 Transcribed locus Phytanoyl-CoA dioxygenase domain containing 1, ENSMUST00000 mRNA (cDNA clone MGC:178922 11.67834 11.092535 1.5 Down 085290 IMAGE:9053914) 5.95264 6.542335 1.5 Up NM_001136055 CD82 antigen (Cd82), transcript variant 1, mRNA chr2:170029045- 2.42413 1.83659 1.5 Down 170034220_R chr2:170029045-170034220_R Discoidin domain receptor family, member 1 (Ddr1), 5.50204 4.914435 1.5 Down NM_007584 transcript variant 1, mRNA chr3:79069438- 1.110745 0.52295 1.5 Down 79073704_R chr3:79069438-79073704_R 11.62619 11.038385 1.5 Down XM_001000226 Gm12270 Membrane protein, palmitoylated, mRNA (cDNA 5.24464 4.65704 1.5 Down NM_008621 clone MGC:18393 IMAGE:4221660) TCDD-inducible poly(ADP-ribose) polymerase, 7.40739 6.821935 1.5 Down NM_178892 mRNA (cDNA clone IMAGE:3485144) Isoleucine-tRNA synthetase 2, mitochondrial, 5.05244 4.46357 1.5 Down NM_198653 mRNA (cDNA clone IMAGE:4922885) Transcriptional adaptor 3 (NGG1 homolog, yeast)- 6.01534 5.426335 1.5 Down NM_133932 like, mRNA (cDNA clone IMAGE:5354837) SAM domain and HD domain, 1, mRNA (cDNA 9.27614 8.690785 1.5 Down NM_018851 clone MGC:14068 IMAGE:4037046) chr6:117827499- 4.78614 4.199835 1.5 Down 117851478_F chr6:117827499-117851478_F