DOCSLIB.ORG

National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances Report Run Date: 09/26/2021 04:22:31 PM 1

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances Report Run Date: 09/26/2021 04:22:31 PM 1 2008 Current Fiscal Year Report: National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances Report Run Date: 09/26/2021 04:22:31 PM 1. Department or Agency 2. Fiscal Year Environmental Protection Agency 2008 3b. GSA 3. Committee or Subcommittee Committee No. National Advisory Committee for Acute Exposure Guideline Levels 2073 for Hazardous Substances 4. Is this New During Fiscal 5. Current 6. Expected Renewal 7. Expected Term Year? Charter Date Date No 11/02/2007 11/02/2009 8a. Was Terminated During 8b. Specific Termination 8c. Actual Term FiscalYear? Authority Date No 9. Agency Recommendation for Next10a. Legislation Req to 10b. Legislation FiscalYear Terminate? Pending? Continue 11. Establishment Authority Agency Authority 12. Specific Establishment 13. Effective 14. Commitee 14c. Authority Date Type Presidential? AGEN 09/28/1995 Continuing No 15. Description of Committee Scientific Technical Program Advisory Board 16a. Total Number of Reports 16 16b. Report Date Report Title 10/01/2007 Final Acute Exposure Guideline Levels for Chlorine Dioxide 10/01/2007 Final Acute Exposure Guideline Levels for Chlorine Trifluoride 10/01/2007 Final Acute Exposure Guideline Levels for Cyclohexylamine 10/01/2007 Final Acute Exposure Guideline Levels for Ethylenediamine 10/01/2007 Final Acute Exposure Guideline Levels for Hydrofluoroether-7100 10/01/2007 Final Acute Exposure Guideline Levels for Tetranitromethane 04/01/2008 Final Acute Exposure Guideline Levels for Allylamine 04/01/2008 Final Acute Exposure Guideline Levels for Ammonia 04/01/2008 Final Acute Exposure Guideline Levels for Aniline 04/01/2008 Final Acute Exposure Guideline Levels for Arsine 04/01/2008 Final Acute Exposure Guideline Levels for Crotonaldehyde 04/01/2008 Final Acute Exposure Guideline Levels for Dimethylhydrazine 04/01/2008 Final Acute Exposure Guideline Levels for Iron pentacarbonyl 04/01/2008 Final Acute Exposure Guideline Levels for Methyl hydrazine 04/01/2008 Final Acute Exposure Guideline Levels for Nickel carbonyl 04/01/2008 Final Acute Exposure Guideline Levels for Phosphine Number of Committee Reports Listed: 16 17a. Open 3 17b. Closed 0 17c. Partially Closed 0 Other Activities 0 17d. Total 3 Meetings and Dates Purpose Start End Development of AEGL Values. 12/05/2007 - 12/07/2007 Development of Proposed AEGL values. 03/03/2008 - 03/05/2008 Development of Proposed AEGLs. 06/25/2008 - 06/27/2008 Number of Committee Meetings Listed: 3 Current FY Next FY 18a(1). Personnel Pmts to Non-Federal Members $0.00 $0.00 18a(2). Personnel Pmts to Federal Members $110,000.00$120,000.00 18a(3). Personnel Pmts to Federal Staff $315,000.00$340,000.00 18a(4). Personnel Pmts to Non-Member Consultants $80,498.00 $70,000.00 18b(1). Travel and Per Diem to Non-Federal Members $24,302.00 $25,000.00 18b(2). Travel and Per Diem to Federal Members $25,010.00 $25,000.00 18b(3). Travel and Per Diem to Federal Staff $3,569.00 $5,000.00 18b(4). Travel and Per Diem to Non-member Consultants $22,657.00 $25,000.00 18c. Other(rents,user charges, graphics, printing, mail, etc.) $1,000.00 $10,000.00 18d. Total $582,036.00$620,000.00 19. Federal Staff Support Years (FTE) 2.50 2.50 20a. How does the Committee accomplish its purpose? In fiscal year 2008 the Committee is continuing its work to develop Acute Exposure Guideline Levels for hazardous substances and its work led to publication of final AEGL values, development of Technical Support Documents for Interim and Proposed AEGL chemicals and continued work on the Committee's Standing Operating Procedures as well as related agenda items. Final AEGL values were published for the following 16 chemicals: allylamine, ammonia, aniline, arsine, crotonaldehyde, dimethyl hydrazine, iron pentacarbonyl, methyl hydrazine, nickel carbonyl, phosphine, chlorine dioxide, chlorine trifluoride, cyclohexylamine, ethylenediamine, hydrofluoroether-7100 and tetranitromethane.Proposed AEGL values were developed for 37 chemicals and published in the Federal Register for public comment on September 19, 2007: 1,2,3-trimethylbenzene; 1,3,5-trimethylbenzene; adamsite; aluminum phosphide; arsenic trioxide; biphenyl; bis-chloromethyl ether; calcium phosphide; cyclohexyl isocyanate; diphenylchloroarsine; ethyldichloroarsine; hexafluoroacetone; hexafluoropropylene; ketene; magnesium aluminum phosphide; methyl chlorosilane; methyl dichloroarsine; Nitogen Mustards (HN-1; HN-2; HN-3); phenyldichloroarsine; phenylmercaptan; potassium phosphide; propargyl alcohol; selenium hexafluoride; silane; sodium phosphide; strontium phosphide; sulfuryl chloride; tetramethoxy silane; trimethoxy silane; vinyl acetate monomer; zinc phosphide.An additonal 62 Interim AEGL values were developed in May 2008 for the following chemicals: acetonitrile; formaldehyde; methyl bromide; methyl chloride; propane; vinyl chloride; acetonitrile; acetaldehyde; ethyl mercaptan; methylene chloride; dimethyl sulfate; chloroacetone; chloroacetyl chloride; dichloroacetyl chloride; methacrylic acid; methyl methacrylate; cumene; styrene; benzonitrile; 1,3-butadiene; chloroacetonitrile; chloroacetaldehyde; malononitrile; hexane; poperidine; proprionaldehyde; methacrylonitrile; ethyl acrylate; n-butyl acrylate; lewisites; sulfur trioxide; titanium tetrachloride; sulfuric acid; hydrogen selenide; boron trifluoride; bromine pentafluoride; oleum; disulfur dichloride; hydrogen iodide; hydrogen bromide; and chlorine pentafluoride; 1,2-Dibromoethane; 2-Ethylhexyl chloroformate; Acrylonitrile; Allyl chloride; Allyl chloroformate; Allyl trichlorosilane; Amyl trichlorosilane; Benzyl chloroformate; Boron tribromide; Bromine chloride; Butyl trichlorosilane; BZ (3-quinuclidinyl benzilate); Carbonyl fluoride; Carbonyl sulfide; Chlorobenzene; Chloromethyltrichlorosilane; Chloropicrin; Chlorosulfonic acid; Chlorotrifluroethylene; Dichlorosilane; Diethyldichlorosilane; Diketene; Dimethylamine; Dimethylchlorosilane; Diphenyldichlorosilane; Docecyltrichlorosilane; Ethyl chloroformate; Ethyl chlorothioformate; Ethylamine; Ethylene chlorohydrin; Ethyltrichlorosilane; Hexyltrichlorosilane; Isobutyl chloroformate; Isopropyl chloroformate; Methacrylaldehyde; Methanesulfonyl chloride; Methyl amine; Methyl chloroformate; Methyl vinyl ketone; Methylvinyldichlorosilane; n-Butyl chloroformate; Nonyltrichlorosilane; Octadecyltrichlorosilane; Octyltrichlorosilane; Osmium tetroxide; Oxygen difluoride; Pentaborane; Phenyl chloroformate; Propyl chloroformate; Propyltrichlorosilane; sec-Butyl chloroformate; Silicon tetrachloride; Silicon tetrafluoride; Stibine (Antimony hydride); Sulfuryl fluoride; Tetrafluoroethylene; Thionyl chloride; Trichloro(dichlorophenyl)silane; Trichlorophenylsilane; Trichlorosilane; Trimethylamine; and Vinyltrichlorosilane.As AEGL values are developed, they will be incorporated into chemical emergency programs of federal agencies, states and private industry and create more effective chemical accident planning, prevention and response programs. 20b. How does the Committee balance its membership? The Committee maintains members that represent federal government, state government, private industry and environmental concerns. Members agree upon scientific validity of AEGL values as the overiding goal to establish scientifically sound chemical emergency programs that protect human health through valid prediction of vulnerability (hazard) zones. This enables legitimate focusing of emergency response during a chemical accident. New members were added from the Union and Medical Professions. 20c. How frequent and relevant are the Committee Meetings? The Committee met three times this fiscal year which was necessary to reach the productive and ambitious schedule of developing AEGL values for 24 chemicals this year. Many topics related to methodologies for developing short-term exposure values for chemicals are discussed and the Standing Operating Procedures for the development of AEGL values is revised as necessary. 20d. Why can't the advice or information this committee provides be obtained elsewhere? The Committee provides a forum for the utilization of expert judgement and debate amongst federal, state, private sector and environmentalist representatives. In addition, the committee setting provides a transparent process to the public. AEGLs also help support chemical counter-terrorism programs in the U.S. 20e. Why is it necessary to close and/or partially closed committee meetings? No meetings were closed to the public. 21. Remarks Designated Federal Officer Paul S. Tobin Program Chair Committee Start End Occupation Member Designation Members Anderson, 05/13/2006 05/14/2009 Wisconsin Department of Health Representative Member Henry Baril, Marc 05/13/2006 05/14/2009 Government of Canada Representative Member Beasley, Full Cmte. Member, U.S. Environmental Protection Agency, Regular Government 06/11/2006 06/10/2010 Lynn HQS - Washington, DC Employee (RGE) Member Becker, Alan 05/13/2006 05/14/2009 Full Cmte. Member, Florida Department of Health Representative Member Benson, Full Cmte. Member, U.S. Environmental Protection Agency - Regular Government 06/30/1996 05/31/2010 Robert Region VIII, Denver, CO Employee (RGE) Member Bernas, 06/30/1997 05/31/2010 Full Cmte. Member Representative Member Edward Regular Government Camacho, Iris 03/10/2008 04/30/2011 Full Cmte. Member, U.S. Environmental Protection Agency Employee (RGE) Member Chapman, Regular Government 06/11/2007 06/10/2010 U.S. Navy, WPAFB, Ohio Gail Employee (RGE) Member Cushmac, Full Cmte. Member, U.S. Department of Transportation - Office Regular
Load more

Recommended publications
  • Five Tyrosines and Two Serines in Human Albumin Are Labeled by the Organophosphorus Agent FP-Biotin
    View metadata, citation and similar papers at core.ac.uk brought to you by CORE Chem. Res. Toxicol. 2008, 21, 1787–1794 1787 provided by PubMed Central Five Tyrosines and Two Serines in Human Albumin Are Labeled by the Organophosphorus Agent FP-Biotin Shi-Jian Ding,† John Carr,† James E. Carlson,‡ Larry Tong,§ Weihua Xue,§ Yifeng Li,† Lawrence M. Schopfer,§ Bin Li,§ Florian Nachon,| Oluwatoyin Asojo,† Charles M. Thompson,⊥ Steven H. Hinrichs,† Patrick Masson,| and Oksana Lockridge*,§ Department of Pathology and Microbiology, UniVersity of Nebraska Medical Center, Omaha, Nebraska 68198, Applied Biosystems, Framingham, Massachusetts 01701, Eppley Institute, UniVersity of Nebraska Medical Center, Omaha, Nebraska 68198, Centre de Recherches d SerVice de Sante´ des Arme´es, Unite´ d’Enzymologie, BP87, 38702 La Tronche Cedex, France, and Department of Biomedical and Pharmaceutical Sciences, UniVersity of Montana, Missoula, Montana 59812 ReceiVed April 23, 2008 Tyrosine 411 of human albumin is an established site for covalent attachment of 10-fluoroethoxyphosphinyl- N-biotinamidopentyldecanamide (FP-biotin), diisopropylfluorophosphate, chlorpyrifos oxon, soman, sarin, and dichlorvos. This work investigated the hypothesis that other residues in albumin could be modified by organophosphorus agents (OP). Human plasma was aggressively treated with FP-biotin; plasma proteins were separated into high and low abundant portions using a proteome partitioning antibody kit, and the proteins were digested with trypsin. The FP-biotinylated tryptic peptides were isolated by binding to monomeric avidin beads. The major sites of covalent attachment identified by mass spectrometry were Y138, Y148, Y401, Y411, Y452, S232, and S287 of human albumin. Prolonged treatment of pure human albumin with chlorpyrifos oxon labeled Y138, Y150, Y161, Y401, Y411, and Y452.
    [Show full text]
  • Aegls Brochure
    4.85 5 5 About the Board on Environmental Studies and Toxicology The Board on Environmental Studies and Toxicology addresses Types of Chemicals Covered in the AEGLs Series environmental pollution problems affecting human health, human impacts on the environment, and the assessment and management of risks to AEGLs values for the chemicals listed below were published in the first human health and the environment. The board’s reports answer questions six volumes of the AEGLs series. AEGLs for additional chemicals will about air and water pollution; solid and hazardous waste; toxicology; continue to be published in subsequent volumes. epidemiology; risk assessment; applied ecology; natural resources; and environmental engineering, economics, law, and policy. Allylamine Hydrogen fluoride Ammonia Iron pentacarbonyl Aniline Methyl hydrazine Arsine Methyl isocyanate About NRC Reports from the National Academies Protecting Chlorine Nerve agents GA [tabun], The National Academies, through its National Research Council reports, Chlorine dioxide GB [sarin], GD [soman], GF, provides a unique public service by working outside the framework of Chlorine trifluoride and VX the Public and government to ensure independent, expert advice on matters of science, Crotonaldehyde Nickel carbonyl technology, and medicine. Today, the National Academies include three Cyclohexylamine Phosgene honorary societies that elect new members to their ranks each year- Diborane Phosphine Emergency the National Academy of Sciences, the National Academy of Engineering, 1,1-Dichloro-1-fluoroethane Propylene glycol dinitrate and the Institute of Medicine-and the National Research Council, the (HCFC-141B) Sulfur mustard operating arm that conducts the bulk of the institution’s Dimethylhydrazine 1,1,1,2-Tetrafluoroethane Workers science-policy and technical work.
    [Show full text]
  • Chemical Intercalation of Zerovalent Metals Into 2D Layered Bi2se3 Nanoribbons † † ‡ † † † § Kristie J
    Article pubs.acs.org/JACS Chemical Intercalation of Zerovalent Metals into 2D Layered Bi2Se3 Nanoribbons † † ‡ † † † § Kristie J. Koski, Colin D. Wessells, Bryan W. Reed, Judy J. Cha, Desheng Kong, and Yi Cui*, , † Department of Materials Science and Engineering, Stanford University, Stanford, California 94305, United States ‡ Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore, California 94550, United States § SLAC National Accelerator Laboratory, Stanford Institute for Materials and Energy Sciences, 2575 Sand Hill Road, Menlo Park, California 94025, United States *S Supporting Information ABSTRACT: We have developed a chemical method to intercalate a variety of zerovalent metal atoms into two-dimen- sional (2D) layered Bi2Se3 chalcogenide nanoribbons. We use a chemical reaction, such as a disproportionation redox reaction, to generate dilute zerovalent metal atoms in a refluxing solution, which intercalate into the layered Bi2Se3 structure. The zerovalent nature of the intercalant allows superstoichiometric intercalation of metal atoms such as Ag, Au, Co, Cu, Fe, In, Ni, and Sn. We foresee the impact of this methodology in establishing novel fundamental physical behaviors and in possible energy applications. 1. INTRODUCTION Ni, and Sn. Some interesting effects that could arise with − 7−10 intercalation are superconductivity, such as in Cu Bi2Se3, Intercalation is the insertion of a guest species into a host 6 lattice. Intercalation into layered materials is essential to battery enhanced conductivity, or possibly opening a surface state gap electrodes, electrochromics, detergents, and solid lubricants and in topological insulator Bi2Se3. This method of zerovalent metal is important in exotic fundamental two-dimensional (2D) intercalation may also be extended to other layered materials.
    [Show full text]
  • Chemical Name Federal P Code CAS Registry Number Acutely
    Acutely / Extremely Hazardous Waste List Federal P CAS Registry Acutely / Extremely Chemical Name Code Number Hazardous 4,7-Methano-1H-indene, 1,4,5,6,7,8,8-heptachloro-3a,4,7,7a-tetrahydro- P059 76-44-8 Acutely Hazardous 6,9-Methano-2,4,3-benzodioxathiepin, 6,7,8,9,10,10- hexachloro-1,5,5a,6,9,9a-hexahydro-, 3-oxide P050 115-29-7 Acutely Hazardous Methanimidamide, N,N-dimethyl-N'-[2-methyl-4-[[(methylamino)carbonyl]oxy]phenyl]- P197 17702-57-7 Acutely Hazardous 1-(o-Chlorophenyl)thiourea P026 5344-82-1 Acutely Hazardous 1-(o-Chlorophenyl)thiourea 5344-82-1 Extremely Hazardous 1,1,1-Trichloro-2, -bis(p-methoxyphenyl)ethane Extremely Hazardous 1,1a,2,2,3,3a,4,5,5,5a,5b,6-Dodecachlorooctahydro-1,3,4-metheno-1H-cyclobuta (cd) pentalene, Dechlorane Extremely Hazardous 1,1a,3,3a,4,5,5,5a,5b,6-Decachloro--octahydro-1,2,4-metheno-2H-cyclobuta (cd) pentalen-2- one, chlorecone Extremely Hazardous 1,1-Dimethylhydrazine 57-14-7 Extremely Hazardous 1,2,3,4,10,10-Hexachloro-6,7-epoxy-1,4,4,4a,5,6,7,8,8a-octahydro-1,4-endo-endo-5,8- dimethanonaph-thalene Extremely Hazardous 1,2,3-Propanetriol, trinitrate P081 55-63-0 Acutely Hazardous 1,2,3-Propanetriol, trinitrate 55-63-0 Extremely Hazardous 1,2,4,5,6,7,8,8-Octachloro-4,7-methano-3a,4,7,7a-tetra- hydro- indane Extremely Hazardous 1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]- 51-43-4 Extremely Hazardous 1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]-, P042 51-43-4 Acutely Hazardous 1,2-Dibromo-3-chloropropane 96-12-8 Extremely Hazardous 1,2-Propylenimine P067 75-55-8 Acutely Hazardous 1,2-Propylenimine 75-55-8 Extremely Hazardous 1,3,4,5,6,7,8,8-Octachloro-1,3,3a,4,7,7a-hexahydro-4,7-methanoisobenzofuran Extremely Hazardous 1,3-Dithiolane-2-carboxaldehyde, 2,4-dimethyl-, O- [(methylamino)-carbonyl]oxime 26419-73-8 Extremely Hazardous 1,3-Dithiolane-2-carboxaldehyde, 2,4-dimethyl-, O- [(methylamino)-carbonyl]oxime.
    [Show full text]
  • Bond Distances and Bond Orders in Binuclear Metal Complexes of the First Row Transition Metals Titanium Through Zinc
    Metal-Metal (MM) Bond Distances and Bond Orders in Binuclear Metal Complexes of the First Row Transition Metals Titanium Through Zinc Richard H. Duncan Lyngdoh*,a, Henry F. Schaefer III*,b and R. Bruce King*,b a Department of Chemistry, North-Eastern Hill University, Shillong 793022, India B Centre for Computational Quantum Chemistry, University of Georgia, Athens GA 30602 ABSTRACT: This survey of metal-metal (MM) bond distances in binuclear complexes of the first row 3d-block elements reviews experimental and computational research on a wide range of such systems. The metals surveyed are titanium, vanadium, chromium, manganese, iron, cobalt, nickel, copper, and zinc, representing the only comprehensive presentation of such results to date. Factors impacting MM bond lengths that are discussed here include (a) n+ the formal MM bond order, (b) size of the metal ion present in the bimetallic core (M2) , (c) the metal oxidation state, (d) effects of ligand basicity, coordination mode and number, and (e) steric effects of bulky ligands. Correlations between experimental and computational findings are examined wherever possible, often yielding good agreement for MM bond lengths. The formal bond order provides a key basis for assessing experimental and computationally derived MM bond lengths. The effects of change in the metal upon MM bond length ranges in binuclear complexes suggest trends for single, double, triple, and quadruple MM bonds which are related to the available information on metal atomic radii. It emerges that while specific factors for a limited range of complexes are found to have their expected impact in many cases, the assessment of the net effect of these factors is challenging.
    [Show full text]
  • Table II. EPCRA Section 313 Chemical List for Reporting Year 2017 (Including Toxic Chemical Categories)
    Table II. EPCRA Section 313 Chemical List For Reporting Year 2017 (including Toxic Chemical Categories) Individually listed EPCRA Section 313 chemicals with CAS numbers are arranged alphabetically starting on page II-3. Following the alphabetical list, the EPCRA Section 313 chemicals are arranged in CAS number order. Covered chemical categories follow. Note: Chemicals may be added to or deleted from the list. The Emergency Planning and Community Right-to-Know Call Center or the TRI-Listed Chemicals website will provide up-to-date information on the status of these changes. See section B.3.c of the instructions for more information on the de minimis % limits listed below. There are no de minimis levels for PBT chemicals since the de minimis exemption is not available for these chemicals (an asterisk appears where a de minimis limit would otherwise appear in Table II). However, for purposes of the supplier notification requirement only, such limits are provided in Appendix C. Chemical Qualifiers Certain EPCRA Section 313 chemicals listed in Table II have parenthetic “qualifiers.” These qualifiers indicate that these EPCRA Section 313 chemicals are subject to the section 313 reporting requirements if manufactured, processed, or otherwise used in a specific form or when a certain activity is performed. An EPCRA Section 313 chemical that is listed without a qualifier is subject to reporting in all forms in which it is manufactured, processed, and otherwise used. The following chemicals are reportable only if they are manufactured, processed, or otherwise used in the specific form(s) listed below: Chemical/ Chemical Category CAS Number Qualifier Aluminum (fume or dust) 7429-90-5 Only if it is a fume or dust form.
    [Show full text]
  • Iron Pentacarbonyl
    Poison Facts: Low Chemicals: Iron Pentacarbonyl Properties of the Chemical Iron carbonyl (pentacarbonyl iron), C5FeO5, is a yellow, oily liquid. It is pyrophoric in air and burns to Fe2O3 (Iron[III] oxide) and decomposes by light to Fe2(CO)9 and CO. It is practically insoluble in water, readily soluble in most organic solvents (ether, acetone, ethyl acetate) and slightly soluble in alcohol. The vapor is heavier than air and may travel along the ground. Distant ignition is possible, and it may explode on heating. It may also spontaneously ignite in contact with air. Iron pentacarbonyl is a strong reducing agent and reacts violently with oxidants. Uses of the Chemical Iron pentacarbonyl is prepared from iron (and iron compounds) and CO. It is used in the manufacture of powdered iron cores for high-frequency coils used in the radio and television industries. It is also used as an anti-knock agent in motor fuels and as a catalyst in organic reactions. Absorption, Distribution, Metabolism and Excretion (ADME) Iron pentacarbonyl can be absorbed into the body by inhalation of the vapor, through the skin or by ingestion. No other pharmacokinetic data is available. Clinical Effects of Acute Exposure • Ocular exposures: Iron pentacarbonyl is a local irritant and may cause irritation and injury to eyes. • Dermal exposures: The chemical may irritate the skin and mucous membranes. It may be absorbed through the skin. • Inhalation exposures: If inhaled, iron pentacarbonyl is a local irritant to the lungs and gastrointestinal tract. Symptoms of acute exposure to high concentrations resemble those of exposures to nickel carbonyl.
    [Show full text]
  • Some Reactions of Tris(Triphenylphosphine )-Dicarbonyliron( 0)
    Indian Journal of Chemistry Vol. 21A, June 1982, pp. 579·582 Some Reactions of Tris(Triphenylphosphine )-dicarbonyliron( 0) S. VANCHEESAN Chemistry Department, Indian Institute of Technology, Madras 600 036 Received 20 October 1981; revised and accepted 15 February 1982 Tris(triphenylphospbine)-dicarbonyliron(O)(I) undergoes substitution reactions with trimethylphosphite, pyri- dine, dimethyl sulphoxide and methylisocyanide. Substitution takes place via dissociation of I to a 1 coordinativel1 unsaturated 16 electron complex, which is a highly reactive unstable intermediate. Both steric and electronic factors playa prominent role in deciding the feasibility of the reaction. Steric factor is expressed in terms of e, the cone angle of the ligand, and electronic factor in terms of Al mode of CO stretching frequency in Ni(CO)aL, where L is the ligand for which the electronic factor is expressed in terms of "CO. Ligands with cone angle e, greater than that of triphenyl- phosphine e.g. t-butylphosphine, do not react. In the reaction of I with molecular hydrogen and bromine, oxidative addition takes place. Diphenylacetylene forms two isomers, whereas carbon disulphide forms a n-complex on reaction with L MONG the d8 iron-phosphine complexes of (PPh3)2]+BF~ in absolute ethanol was allowed to the type fe(CO)6_" (PPh3) •• (where x = 1 to react overnight with triphenylphosphine in the A 3), the complexes with x = 1 and 2 had been presence of lithium metal. The resulting micro- studied to some extent>", Mono- and bis-phosphine crystalline solid was filtered and freed from phos- complexes can be prepared= by the reaction of phos- phine using hot ethanol and filtered.
    [Show full text]
  • Ttl Iii26 (C) 28
    USOO6610977B2 (12) United States Patent (10) Patent No.: US 6,610,977 B2 Megerle (45) Date of Patent: Aug. 26, 2003 (54) SECURITY SYSTEM FOR NBC-SAFE 5,692,029 A 11/1997 Husseiny et al. BUILDING 5,692,446 A 12/1997 Becker et al. 5,866.430 A 2/1999 Grow (75) Inventor: Clifford Megerle, Manassas, VA (US) 5,915,268 A 6/1999 Linker et al. 5,965,882 A 10/1999 Megerle et al. (73) Assignee: Lockheed Martin Corporation, 6,073,499 A 6/2000 Settles Bethesda, MD (US) 6,100,698 A 8/2000 Megerle et al. OTHER PUBLICATIONS * ) Notice: Subject to anyy disclaimer, the term of this patent is extended or adjusted under 35 U.S. Pub: 2003/0009661 A1, “Security System and Method U.S.C. 154(b) by 53 days. of Security Service Business”, Tsutsumi et al. (Jan. 9, 2003 ).* (21) Appl. No.: 09/969,050 * cited by examiner (22) Filed: Oct. 1, 2001 Primary Examiner John R. Lee O O ASSistant Examiner Zia R. Hashmi (65)65 PriorO PublicationCaO Data (74) Attorney, Agent, or Firm-Simpson & Simpson, PLLC US 2003/0085348 A1 May 8, 2003 (57) ABSTRACT (51) Int. Cl." ................................................ G01N 23/00 (52) U.S. Cl. ........................ 250,287: 250/286, 73,232. A method and apparatus for Screening an object for the 73/28.01, 73/23; 7323,36. 37s'ss. 37ss6. presence of an explosive, chemical warfare agent, biological s s s 37s?is6 warfare agent, drug, metal, weapon, and/or radioactive (58) Field of Search 250/287, 286; material.
    [Show full text]
  • Organo-Transition Metal Chemistry Some Studies
    ORGANO-TRANSITION METAL CHEMISTRY SOME STUDIES IN ORGANO-TRANSITION METAL CHEMISTRY By COLIN CRINDROD, B.Sc. A Thesis Submitted to the Faculty of Graduate Studies in Partial Fulfilment of the Requirements for the Degree Master of Science McMaster University October 1966 MASTER OF SCIENCE (1966) MCMASTER UNIVERSITY (Chemistry) Hamilton, Ontario TITLE: Some Studies in Organo-Transition Metal Chemistry AUTHOR: Colin Grindrod, B.Sc. (Manchester University) SUPERVISOR: Dr. P. M. Maitlis NUMBER OF PAGES: iv, 71 SCOPE AND CONTENTS: The work described is an extension of the ligand-transfer reactions of substituted cyclobutadienes and cyclopentadienyls previously carried out by Maitlis et al. Efforts were directed particularly to ligand­ transfer reactions of n-allyl-transition metal complexes. The reactions of organic halides with metal carbonyls were also studied in attempts to isolate new organometallic derivatives. (ii) ACKNOWLEDGEMENTS The author wishes to express his sincere gratitude for the stimulating advice and constant encouragement provided by Dr. P. M. Maitlis, under whose guidance this work was carried out. Thanks are also extended to Imperial Oil Co. Ltd. for providing the financial support which made this study possible. (iii) CONTENTS Page INTRODUCTION Historical................................... 1 Cyclobutadiene-transition metal oompeeees... 7 Ligand-transfer reactions................... 10 Allyl-transition metal complexes............ 13 Reactions of metal carbonyls with organic halides.... ..................... 25 DISCUSSION
    [Show full text]
  • SUMMARY of PARTICULARLY HAZARDOUS SUBSTANCES (By
    SUMMARY OF PARTICULARLY HAZARDOUS SUBSTANCES (by alpha) Key: SC -- Select Carcinogens RT -- Reproductive Toxins AT -- Acute Toxins SA -- Readily Absorbed Through the Skin DHS -- Chemicals of Interest Revised: 11/2012 ________________________________________________________ ___________ _ _ _ _ _ _ _ _ _ _ _ ||| | | | CHEMICAL NAME CAS # |SC|RT| AT | SA |DHS| ________________________________________________________ ___________ | _ | _ | _ | _ | __ | | | | | | | 2,4,5-T 000093-76-5 | | x | | x | | ABRIN 001393-62-0 | | | x | | | ACETALDEHYDE 000075-07-0 | x | | | | | ACETAMIDE 000060-35-5 | x | | | | | ACETOHYDROXAMIC ACID 000546-88-3 ||x| | x | | ACETONE CYANOHYDRIN, STABILIZED 000075-86-5 | | | x | | x | ACETYLAMINOFLUORENE,2- 000053-96-3 | x | | | | | ACID MIST, STRONG INORGANIC 000000-00-0 | x | | | | | ACROLEIN 000107-02-8 | | x | x | x | | ACRYLAMIDE 000079-06-1 | x | x | | x | | ACRYLONITRILE 000107-13-1 | x | x | x | x | | ACTINOMYCIN D 000050-76-0 ||x| | x | | ADIPONITRILE 000111-69-3 | | | x | | | ADRIAMYCIN 023214-92-8 | x | | | | | AFLATOXIN B1 001162-65-8 | x | | | | | AFLATOXIN M1 006795-23-9 | x | | | | | AFLATOXINS 001402-68-2 | x | | x | | | ALL-TRANS RETINOIC ACID 000302-79-4 | | x | | x | | ALPRAZOMAN 028981-97-7 | | x | | x | | ALUMINUM PHOSPHIDE 020859-73-8 | | | x | | x | AMANTADINE HYDROCHLORIDE 000665-66-7 | | x | | x | | AMINO-2,4-DIBROMOANTHRAQUINONE 000081-49-2 | x | | | | | AMINO-2-METHYLANTHRAQUINONE, 1- 000082-28-0 | x | | | | | AMINO-3,4-DIMETHYL-3h-IMIDAZO(4,5f)QUINOLINE,2- 077094-11-2 | x | | | | | AMINO-3,8-DIMETHYL-3H-IMIDAZO(4,5-f)QUINOXALINE,
    [Show full text]
  • Metal Carbonyls
    MODULE 1: METAL CARBONYLS Key words: Carbon monoxide; transition metal complexes; ligand substitution reactions; mononuclear carbonyls; dinuclear carbonyls; polynuclear carbonyls; catalytic activity; Monsanto process; Collman’s reagent; effective atomic number; 18-electron rule V. D. Bhatt / Selected topics in coordination chemistry / 2 MODULE 1: METAL CARBONYLS LECTURE #1 1. INTRODUCTION: Justus von Liebig attempted initial experiments on reaction of carbon monoxide with metals in 1834. However, it was demonstrated later that the compound he claimed to be potassium carbonyl was not a metal carbonyl at all. After the synthesis of [PtCl2(CO)2] and [PtCl2(CO)]2 reported by Schutzenberger (1868) followed by [Ni(CO)4] reported by Mond et al (1890), Hieber prepared numerous compounds containing metal and carbon monoxide. Compounds having at least one bond between carbon and metal are known as organometallic compounds. Metal carbonyls are the transition metal complexes of carbon monoxide containing metal-carbon bond. Lone pair of electrons are available on both carbon and oxygen atoms of carbon monoxide ligand. However, as the carbon atoms donate electrons to the metal, these complexes are named as carbonyls. A variety of such complexes such as mono nuclear, poly nuclear, homoleptic and mixed ligand are known. These compounds are widely studied due to industrial importance, catalytic properties and structural interest. V. D. Bhatt / Selected topics in coordination chemistry / 3 Carbon monoxide is one of the most important π- acceptor ligand. Because of its π- acidity, carbon monoxide can stabilize zero formal oxidation state of metals in carbonyl complexes. 2. SYNTHESIS OF METAL CARBONYLS Following are some of the general methods of preparation of metal carbonyls.
    [Show full text]