fmicb-08-00804 April 29, 2017 Time: 14:57 # 1 ORIGINAL RESEARCH published: 03 May 2017 doi: 10.3389/fmicb.2017.00804 Efficacy of (C)-Lariciresinol to Control Bacterial Growth of Staphylococcus aureus and Escherichia coli O157:H7 Vivek K. Bajpai1†, Shruti Shukla2†, Woon K. Paek3, Jeongheui Lim3*, Pradeep Kumar4*, Pankaj Kumar5 and MinKyun Na6* 1 Department of Applied Microbiology and Biotechnology, Microbiome Laboratory, Yeungnam University, Gyeongsan, South Korea, 2 Department of Energy and Materials Engineering, Dongguk University, Seoul, Seoul, South Korea, 3 National Edited by: Science Museum, Ministry of Science, ICT and Future Planning, Daejeon, South Korea, 4 Department of Forestry, North Luis Cláudio Nascimento da Silva, Eastern Regional Institute of Science and Technology, Nirjuli, India, 5 Department of Microbiology, Dolphin (PG) College of CEUMA University, Brazil Science & Agriculture, Fatehgarh Sahib, India, 6 College of Pharmacy, Chungnam National University, Daejeon, South Korea Reviewed by: Diego Garcia-Gonzalo, This study was undertaken to assess the antibacterial potential of a polyphenolic University of Zaragoza, Spain Dinesh Yadav, compound (C)-lariciresinol isolated from Rubia philippinensis against selected Deen Dayal Upadhyay Gorakhpur foodborne pathogens Staphylococcus aureus KCTC1621 and Escherichia coli University, India C Osmar Nascimento Silva, O157:H7. ( )-Lariciresinol at the tested concentrations (250 mg/disk) evoked a Universidade Católica Dom Bosco, significant antibacterial effect as a diameter of inhibition zones (12.1–14.9 mm) with Brazil minimum inhibitory concentration (MIC), and minimum bactericidal concentration values *Correspondence: of 125–250 and 125–250 mg/mL, respectively. Furthermore, (C)-lariciresinol at MIC Pradeep Kumar C
[email protected] showed reduction in bacterial cell viabilities, efflux of potassium (K ) ions and release Jeongheui Lim of 260 nm materials against E.