Cataract Surgery? P.2P26
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MASTERS OF SURGERY P. 62 • DEVELOPMENTS IN GENETIC TESTING P. 16 TELEMEDICINE IN PEDIATRIC RETINAL DISEASE P. 60 • WILLS EYE RESIDENT CASE SERIES P. 85 ARE TWO MIGS BETTER THAN ONE? P. 70 • NEW TARGETS FOR ALLERGY TREATMENT P. 66 Review of Ophthalmology Vol. XXII, No. 3 • March 2015 • Who’s Getting Femto Cataract Surgery • Are Two Cataract Surgery • Are Two Getting Femto Review of Ophthalmology Vol. XXII, 2015 • Who’s No. 3 • March March 2015 reviewofophthalmology.com CATARACT ISSUE Who’s Getting Femto Laser Cataract MIGS B MIGS Surgery? etter Than One? • New Targets for Allergy Treatment One? • New Targets etter Than P.2P2 6 What the Data Says About Femtosecond Cataract Surgery P. 36 Reader Survey: Cataract Surgery P. 44 001_rp0315_fc.indd 1 2/20/15 4:22 PM Cornea. Capsule. Lens. One optimized solution. Shown with the VERION™ Digital Marker Demand precision across the entire anterior segment. Part of The Cataract Refractive Suite by Alcon, the LenSx® Laser is designed to optimize performance across the entire anterior segment to deliver: • Precise primary and • Complete, reproducible • Versatile fragmentation secondary corneal incisions, capsulotomies with patterns and arcuate incisions pristine edges1 1. Alcon data on fi le. Visit LenSxLasers.com, or talk to your local Alcon representative about how the LenSx® Laser can help enhance the precision of cataract surgery with AcrySof® IOLs. © 2014 Novartis 11/14 LSX14078JAD COMPLETE PRECISION RP0315_Alcon Lensx.indd 1 2/9/15 2:23 PM ACRYSOF® IQ INTRAOCULAR LENSES IMPORTANT PRODUCT INFORMATION EVERY MONDAY CAUTION: FEDERAL USA LAW RESTRICTS THIS DEVICE TO THE SALE BY OR ON THE ORDER OF A PHYSICIAN. INDICATIONS: THE ACRYSOF® IQ POSTERIOR CHAMBER INTRAOCULAR LENS IS INTENDED FOR THE REPLACEMENT OF THE HUMAN LENS TO ACHIEVE VISUAL CORRECTION OF APHAKIA IN ADULT PATIENTS FOLLOWING CATARACT SURGERY. THIS LENS IS INTENDED FOR PLACEMENT IN THE CAPSULAR BAG. E-NEWS WARNINGS/PRECAUTIONS: CAREFUL PREOPERATIVE EVALUATION AND SOUND CLINICAL JUDGMENT SHOULD BE USED BY THE SURGEON TO DECIDE THE RISK/BENEFIT RATIO BEFORE IMPLANTING A LENS IN A PATIENT WITH ANY OF THE CONDITIONS YOU DESCRIBED IN THE DIRECTIONS FOR USE LABELING. CAUTION SHOULD BE USED PRIOR TO LENS ENCAPSULATION TO AVOID LENS DECENTRATIONS OR DISLOCATIONS. CAN STUDIES HAVE SHOWN THAT COLOR VISION DISCRIMINATION IS NOT ADVERSELY AFFECTED IN INDIVIDUALS WITH THE ACRYSOF® NATURAL IOL AND NORMAL COLOR VISION. THE EFFECT ON VISION OF THE ACRYSOF® NATURAL IOL IN SUBJECTS WITH HEREDITARY COLOR VISION DEFECTS AND ACQUIRED COLOR VISION DEFECTS SECONDARY TO OCULAR DISEASE E.G., USE GLAUCOMA, DIABETIC RETINOPATHY, CHRONIC UVEITIS, AND OTHER RETINAL OR OPTIC NERVE DISEASES HAS NOT BEEN STUDIED. DO NOT RESTERILIZE; DO NOT STORE OVER 45° C; USE ONLY STERILE IRRIGATING SOLUTIONS SUCH AS BSS® OR BSS PLUS® STERILE INTRAOCULAR IRRIGATING SOLUTIONS. ATTENTION: REFERENCE THE DIRECTIONS FOR USE LABELING FOR A COMPLETE LISTING OF INDICATIONS, WARNINGS AND PRECAUTIONS. Have you been receiving and reading custom e-blasts from LENSX® LASER IMPORTANT PRODUCT INFORMATION Review of Ophthalmology? CAUTION: UNITED STATES FEDERAL LAW RESTRICTS THIS DEVICE TO SALE AND USE BY OR ON THE ORDER OF A PHYSICIAN OR LICENSED EYE CARE PRACTITIONER. If not, you’re missing out on INDICATION: THE LENSX® LASER IS INDICATED FOR USE IN PATIENTS UNDERGOING CATARACT SURGERY FOR REMOVAL OF valuable information! THE CRYSTALLINE LENS. INTENDED USES IN CATARACT SURGERY INCLUDE ANTERIOR CAPSULOTOMY, PHACOFRAGMENTATION, AND THE CREATION OF SINGLE PLANE AND MULTIPLANE ARC CUTS/INCISIONS IN THE CORNEA, EACH OF WHICH MAY BE PERFORMED EITHER INDIVIDUALLY OR CONSECUTIVELY DURING THE SAME PROCEDURE. You’re a busy practitioner and not surprisingly, your e-mail inbox is often full. Fortunately, when RESTRICTIONS: PATIENTS MUST BE ABLE TO LIE FLAT AND MOTIONLESS IN A SUPINE POSITION. PATIENT MUST BE ABLE TO you scan through the sender list, determining UNDERSTAND AND GIVE AN INFORMED CONSENT. PATIENTS MUST BE ABLE TO TOLERATE LOCAL OR TOPICAL ANESTHESIA. PATIENTS WITH ELEVATED IOP SHOULD USE TOPICAL STEROIDS ONLY UNDER CLOSE MEDICAL SUPERVISION. which messages to delete and which to save or read, you can feel confi dent knowing that e-blasts CONTRAINDICATIONS: CORNEAL DISEASE THAT PRECLUDES APPLANATION OF THE CORNEA OR TRANSMISSION OF LASER LIGHT AT 1030 NM WAVELENGTH. DESCEMETOCELE WITH IMPENDING CORNEAL RUPTURE. PRESENCE OF BLOOD OR OTHER from Review of Ophthalmology, a Jobson Medical MATERIAL IN THE ANTERIOR CHAMBER. POORLY DILATING PUPIL, SUCH THAT THE IRIS IS NOT PERIPHERAL TO THE INTENDED Information LLC publication, contain the most DIAMETER FOR THE CAPSULOTOMY. CONDITIONS WHICH WOULD CAUSE INADEQUATE CLEARANCE BETWEEN THE INTENDED current and comprehensive information available in CAPSULOTOMY DEPTH AND THE ENDOTHELIUM APPLICABLE TO CAPSULOTOMY ONLY. PREVIOUS CORNEAL INCISIONS THAT the fi eld to keep you on the cutting edge. MIGHT PROVIDE A POTENTIAL SPACE INTO WHICH THE GAS PRODUCED BY THE PROCEDURE CAN ESCAPE. CORNEAL THICKNESS REQUIREMENTS THAT ARE BEYOND THE RANGE OF THE SYSTEM. CORNEAL OPACITY THAT WOULD INTERFERE WITH THE LASER BEAM. HYPOTONY OR THE PRESENCE OF A CORNEAL IMPLANT. RESIDUAL, RECURRENT, ACTIVE OCULAR OR EYELID DISEASE, Review of Ophthalmology’s online stable of prod- INCLUDING ANY CORNEAL ABNORMALITY FOR EXAMPLE, RECURRENT CORNEAL EROSION, SEVERE BASEMENT MEMBRANE ucts includes editorial newsletters and promotional DISEASE. HISTORY OF LENS OR ZONULAR INSTABILITY. ANY CONTRAINDICATION TO CATARACT OR KERATOPLASTY. THIS information about new products, treatments and DEVICE IS NOT INTENDED FOR USE IN PEDIATRIC SURGERY. surgical techniques, as well as alerts on continuing WARNINGS: THE LENSX® LASER SYSTEM SHOULD ONLY BE OPERATED BY A PHYSICIAN TRAINED IN ITS USE. education courses for ophthalmologists. THE LENSX® LASER DELIVERY SYSTEM EMPLOYS ONE STERILE DISPOSABLE LENSX® LASER PATIENT INTERFACE CONSISTING OF Our FREE weekly e-newsletter, Review AN APPLANATION LENS AND SUCTION RING. THE PATIENT INTERFACE IS INTENDED FOR SINGLE USE ONLY. THE DISPOSABLES USED IN CONJUNCTION WITH ALCON® INSTRUMENT PRODUCTS CONSTITUTE A COMPLETE SURGICAL SYSTEM. USE OF of Ophthalmology Online, brings you DISPOSABLES OTHER THAN THOSE MANUFACTURED BY ALCON MAY AFFECT SYSTEM PERFORMANCE AND CREATE POTENTIAL the latest in ophthalmic research, as well HAZARDS. as industry news. In an eff ort to keep eyecare professionals informed, this resource is THE PHYSICIAN SHOULD BASE PATIENT SELECTION CRITERIA ON PROFESSIONAL EXPERIENCE, PUBLISHED LITERATURE, AND waiting in your inbox every Monday morning. EDUCATIONAL COURSES. ADULT PATIENTS SHOULD BE SCHEDULED TO UNDERGO CATARACT EXTRACTION. PRECAUTIONS: DO NOT USE CELL PHONES OR PAGERS OF ANY KIND IN THE SAME ROOM AS THE LENSX® LASER. DISCARD Retina Online, our free monthly USED PATIENT INTERFACES AS MEDICAL WASTE. e-newsletter, is for retina specialists and AES/COMPLICATIONS: CAPSULOTOMY, PHACOFRAGMENTATION, OR CUT OR INCISION DECENTRATION. INCOMPLETE OR general INTERRUPTED CAPSULOTOMY, FRAGMENTATION, OR CORNEAL INCISION PROCEDURE. CAPSULAR TEAR. CORNEAL ABRASION ophthalmologists interested in OR DEFECT. PAIN. INFECTION. BLEEDING. DAMAGE TO INTRAOCULAR STRUCTURES. ANTERIOR CHAMBER FLUID LEAKAGE, enhancing their knowledge on the topics of retina ANTERIOR CHAMBER COLLAPSE. ELEVATED PRESSURE TO THE EYE. and related disease diagnosis and treatment, as ATTENTION: REFER TO THE LENSX® LASER OPERATOR’S MANUAL FOR A COMPLETE LISTING OF INDICATIONS, WARNINGS AND well as the latest in surgical procedures. PRECAUTIONS. Unfamiliar with our products? Visit www.reviewofophthalmology.com and check out our newsletter archives. Go to www.jobson.com/globalEmail/default.aspx to sign up for the e-newsletters that interest you. © 2014 Novartis 11/14 LSX14078JAD March 2012 | Revophth.com | 3 003_rp0315_ads.indd 3 2/20/15 3:21 PM 2015_RPonline_house_half.indd 90 2/12/15 2:43 PM REVIEW NEWS Volume XXII • No. 3 • March 2015 Kellogg Center Study Finds Generics Improve Adherence When patients with glaucoma switched the study had health insurance. ence, it may be a good idea to switch from a brand name drug to its ge- Dr. Stein and colleagues found from a brand name to a generic drug,” neric counterpart, they were more that patients who remained on advises Dr. Stein. He also encourages likely to take their medication as brand name drugs were 39-percent patients to ask their doctors if a ge- directed compared to those who re- more likely to experience a decline neric alternative is available and ap- mained on the brand name drug, ac- in adherence compared to those propriate for their circumstances. cording to a study published online who switched to the newly available in Ophthalmology. Researchers at generic drug latanoprost. The re- the University of Michigan Kellogg searchers cited several factors associ- Ranibizumab Eye Center and College of Phar- ated with improved adherence rates, macy studied medication adherence among them, the use of the generic Restores Diabetic rates 18 months before and after the drug once it became available and fi rst generic prostaglandin analogue lower copays after the generic drug Vision Loss glaucoma drug became available in became available. Ranibizumab, commonly used to treat March 2011. The Michigan researchers found age-related vision loss, also reverses Despite the potentially dire con- that black patients had decreased vision loss caused by diabetes among sequences for non-adherence, many adherence compared to white pa- Hispanic and non-Hispanic