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Supplementary Figure 1. Forest Plot Showing the Proportion of Ascites in Patients with Tusanqi- Related SOS

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Supplementary Figure 1. Forest Plot Showing the Proportion of Ascites in Patients with Tusanqi- Related SOS Supplementary Figure 1. Forest plot showing the proportion of ascites in patients with tusanqi- related SOS. Supplementary Figure 2. Forest plot showing the proportion of hepatomegaly in patients with tusanqi-related SOS. Supplementary Figure 3. Forest plot showing the proportion of jaundice in patients with tusanqi- related SOS. Supplementary Figure 4. Forest plot showing the proportion of plueral effusion in patients with tusanqi-related SOS. Supplementary Figure 5. Forest plot showing the proportion of lower limbs edema in patients with tusanqi-related SOS. Supplementary Figure 6. Forest plot showing the proportion of splenomegaly in patients with tusanqi-related SOS. Supplementary Figure 7. Forest plot showing the proportion of upper gastrointestinal bleeding in patients with tusanqi-related SOS. Supplementary Figure 8. Forest plot showing the proportion of gastroesophageal varices in patients with tusanqi-related SOS. Supplementary Figure 9. Forest plot showing the proportion of hepatic encephalopathy in patients with tusanqi-related SOS. Supplementary Table 1. Exclusion of relevant studies with overlapping data Type Excluded First of Affiliations Journals or author papers included Zhang Yao Wu Bu Liang Fan Ying Za Zhi 2009;11(6);425-426 Excluded Beijing Ditan Hospital Junxia Affiliated to Capital Cheng Medical University Zhong Guo Gan Zang Bing Za Zhi 2012;4(4);26-28 Included Danying Wu Shi Yong Gan Zang Bing Za Zhi 2010;13(2);139-140 Excluded Nanjing General Hospital Xiaowei of Nanjing Military Hou Command Hu Li Yan Jiu 2011;25(1);178-179 Included Case Yu report Duan (4) Ren Min Jun Yi 2011;54(3);215 Excluded PLA 155 Central Hongguang Hospital, Kaifeng, Henan Peng Gong Neng Yu Fen Zi Yi Xue Ying Xiang Xue 2012;1(4);297-298 Included Peili Tongji Hospital Affiliated Gao Zhong Guo Zhong Xi Yi Jie He Xiao Hua Za Zhi 2006;14(6);416- Excluded to Tongji Medical Xinsheng 417 College of Huazhong Huang University of Science Lin Chuang Xiao Hua Bing Za Zhi 2008;20(1);26-28.32 Included and Tecnology Huanjun Case Zhong Xian Dai Shi Yong Yi Xue 2010;22(7);787-788 Excluded series Jianfeng Huzhou Central Hospital type I Yao Xian Dai Shi Yong Yi Xue 2012;24(8);935-936 Included (17) Lidi Chen Zhong Hua Ling Chuang Gan Ran Bing Za Zhi 2010;3(2);76-79 Excluded Huazhong Taizhou Hospital Geng Affiliated to Wenzhou Zhong Hua Fang She Xue Za Zhi 2009;43(3);312-314 Excluded Caizheng Medical College Chen Lin Chuang Gan Dan Bing Za Zhi 2012;28(5);376-379 Included Huazhong Fang Zhong Hua Chuan Ran Bing Za Zhi 2007;25(6);373-374 Excluded Guoping Yang Chang Zhou Shi Yong Yi Xue 2010;26(5);292-293 Excluded Miaomiao Zhang Xian Dai Zhong Xi Yi Jie He Za Zhi 2012;21(7);767-768 Excluded The Third People's Huifen Hospital of Changzhou Zhang Jie Ru Fang She Xue Za Zhi 2012;21(12);987-990 Excluded Luxi Zhang Su Zhou Da Xue Xue Bao (Yi Xue Ban) 2009;29(6);1196-1198 Excluded Weimin Yao Xian Dai Zhong Xi Yi Jie He Za Zhi 2014;23(30);3371-3372 Included Lingdi Tongji Hospital Affiliated Zhu Zhong Hua Xian Dai Hu Li Za Zhi 2008;14(15);1702-1703 Excluded to Tongji Medical Xiuqin College Huazhong University of Science Zhu Hu Li Yan Jiu 2011;25(5);1272-1273 Included and Technology Xiuqin Ma Lin Chuang Yi Xue 2006;26(5);86 Excluded Lixin Zhang Zhong Hua Fang She Xue Za Zhi 2006;40(3);250-254 Excluded Xianju County People's Guohua Hospital Ma Zhe Jiang Lin Chuang Yi Xue 2008;10(5);593-594 Included Xinguang Xu Haibo Zhong Guo Xiang Cun Yi Yao 2010;17(9);45 Included Huang Zhong Xi Yi Jie He Gan Bing Za Zhi 2011;21(5);280-281+323 Excluded Xiehe Hospital Affiliated Xiaoming to Tongji Medical college Tang Fang She Xue Shi Jian 2012;27(11);1235-1237 Excluded Huazhong University of Wenjuan Science and Technology Ye Hua Dong Ke Ji Da Xue Shuo Shi Xue Wei Lun Wen (2013) Included Tianhe Xinchang County Wu Zhong Hua Gan Zang Bing Za Zhi 2013;21(8);635-636 Excluded People's Hospital Xinjun Yu Zhong Guo Xiang Cun Yi Yao 2012;19(16);62-63 Excluded Mengyong Qing Zhu Zhong Guo Chao Sheng Zhen Duan 50 Nian Ji Di Shi Yu Jie Quan Guo Chao Sheng Yi Xue Xue Shu Hui Yi 2008;260- Excluded Zidong 261 Zhang Zhe Jiang Chuang Shang Wai Ke 2009;14(1);90 Excluded Manping Zhang Zhe Jiang Zhong Xi Yi Jie He Za Zhi 2013;23(8);647-649 Included Kui Chen Zhong Guo Yi Xue Ying Xiang Xue Za Zhi 2010;18(2);154-156 Excluded Shuang General Hospital of Armed Police Forces Zhang Zhong Guo Xian Dai Pu Tong Wai Ke Jin Zhan 2014;17(3);239- Included Wei 241 Chai Wu Jing Yi Xue 2007;18(11);828-830 Excluded Peoples Liberation Army Guojun General Hospital Ding Jie Fang Jun Yi Xue Yuan Xue Bao 2013;34(1);34-36+52 Included Pengpeng Zhang Zhong Hua Yi Xue Hui Di Shi Liu Ci Quan Guo Bing Du Xing Excluded The First Affiliated Yanting Gan Yan Ji Gan Bing Xue Shu Hui Yi 2013;489-490 Hospital of Nanjing Zhang Medical University Lin Chuang Gan Dan Bing Za Zhi 2013;29(12);936-939 Included Yanting Chen Zhe Jiang Da Xue Shuo Shi Xue Wei Lun Wen (2006) Excluded Hongtan Case Chen Zhong Hua Xiao Hua Za Zhi 2006;26(4);224-226 Excluded series Yipeng type II Huang 2006 Nian Zhe Jiang Sheng Chao Sheng Yi Xue Xue Shu Nian (10) Excluded The First Affiliated Zhiliang Hui 2006;60-61 Hospital of Zhejiang Tao Zhe Jiang Da Xue Shuo Shi Xue Wei Lun Wen (2011) Excluded University Medical Jingjing College Ying Lin Chuang Fang She Xue Za Zhi 2011;30(9);1302-1305 Excluded Shihong Jiang Zhong Guo Chao Sheng Yi Xue Za Zhi 2008;24(10);951-955 Included Tian'an Zhu Zhong Hua Xiao Hua Za Zhi 2012;32(9);620-624 Included Wanlin Lin Hai Nan Yi Xue 2011;22(15);143-144 Excluded Li The Third People's Liu Shi Yong Gan Zang Bing Za Zhi 2008;11(2);107-109 Excluded Hospital of Changzhou Jianhong Gong Zhong Xi Yi Jie He Gan Bing Za Zhi 2012;22(3);144-145 Included Jing Supplementary Table 2. Information of 56 case reports Admission First No. Journal (Year) Affiliations Provinces date of author Pts. cases Not Zhong Da Hospital Affiliated to Dongnan Jian Kang Guan Li (2014) Hunan 1 Not reported reported University Cao Xinhuang Hospital Affiliated to Shanghai Zhong Guo Yi Xue Qian Yan Za Zhi (2012) Shanghai 1 Not reported Haixia Jiaotong University Medical College Cao Zhong Guo Fa Yi Xue Hui Fa Yi Lin Chuang Anshan City Public Security Bureau Liaoning 1 1999.12 Zhe Xue Xue Shu Yan Tao Hui (2003) Criminal Investigation Detachment Tongji Hospital Affiliated to Tongji Medical Chen 2013.1.12 Lin Chuang Xiao Hua Bing Za Zhi (2013) College of Huazhong University of Hubei 2 Shanglin Science and Technology 2013.2.27 Chen The First Hospital Affiliated to Zhejiang 2000.8.8 Zhong Hua Gan Zang Bing Za Zhi (2005) Zhejiang 2 Weixing University Medical College 2002.9.11 Cheng Beijing Ditan Hospital Affiliated to Capital 2009.5.22 Zhong Guo Gan Zang Bing Za Zhi (2012) Beijing 2 Danying Medical University 2009.6.4 2011.12.4 Cong Dang Dai Yi Xue (2014) Wendeng City People's Hospital Shandong 3 2013.2.11 Ming 2013.2.22 Dai Sir Run Run Shaw Hospital Affiliated to Zhong Hua Xiao Hua Za Zhi (2007) Zhejiang 1 Not reported ning Zhejiang University Medical College Dong The First Hospital Affiliated to Zhejiang 2008.9.30 Zhong Hua Xian Dai Hu Li Za Zhi (2011) Zhejiang 2 Qunya University Medical College 2008.10.8 Fang Zhong Hua Lin Chuang Yi Shi Za Zhi (2013) Tongling County People's Hospital Anhui 1 Not reported Jiman 2005.12.14 Fang Zhong Ri You Hao Yi Yuan Xue Bao (2010) The China-Japan Friendship Hospital Beijing 3 2006.6.12 Long 2009.7.9 Guo Shan Xi Zhong Yi (2009) Tianjin University of TCM Tianjin 1 2007.4.13 Qingbo Hong Yong Gui Zhou Yi Yao (2012) Chishui City People's Hospital Guizhou 1 2011 Hou Nanjing General Hospital of Nanjing 2008.3 Hu Li Yan Jiu (2011) Jiangsu 2 Yu Military Command 2009.2 Zhong Guo Ling Chuang Yi Xue Ying Xiang Za Affiliated Hospital of Shaoxing College of Not reported Hu Jinsong Zhejiang 2 Zhi (2014) Arts and Science Not reported Hua Renji Hospital Affiliated to Shanghai Wei Chang Bing Xue (2010) Shanghai 1 Not reported Jing Jiaotong University Medical College Tongji Hospital Affiliated to Tongji Medical 2004.12.31 Huang Lin Chuang Xiao Hua Bing Za Zhi (2008) College of Huazhong University of Hubei 3 2006.3.23 Huanjun Science and Technology 2006.10.3 Lan Zhou Da Xue Shuo Shi Xue Wei Lun Wen Lai Ruimin Lanzhou University Gansu 1 2012.6.12 (2013) Li PLA 302 Hospital Liver Failure Treatment Gan Zang (2010) Beijing 1 2009.4.16 Chen Research Center Zhong Hua Hu Li Xue Hui 2009 Nian Quan Li Guo Hu Li Guan Li Xue Shu Jiao Liu Ji Zhuan Huangshi City Fifth Hospital Hubei 1 Not reported Hong Ti Jiang Zuo Hui Yi (2009) Li Zhongshan Hospital Affiliated to Fudan 2008.6.27 Zhong Guo Ling Chuang Yi Xue (2009) Shanghai 2 Hong University 2008.12.26 The Second People's Hospital of Wuxi Li Jianping Zhong Hua Gan Dan Wai Ke Za Zhi (2001) Jiangsu 1 Not reported City Chuan Ran Bing Zhen Zhi Gao Feng Lun Tan Li 2007.1.20 Ji 2007 Nian Zhe Jiang Sheng Gan Ran Bing Lishui City People's Hospital Zhejiang 2 Libo Xue, Gan Bing Xue Xue Shu Nian Hui (2007) 2007.3.8 Li Shangri Zhong Xi Yi Jie He Gan Bing Za Zhi (2007) The Second Hospital of Huangshi City Hubei 1 2006.6 Li Not Qiu Yi Wen Yao (2012) Not reported 1 Not reported Xinqiao reported 2004.12.24 Li Yuxiang Lin Chuang Gan Dan Bing Za Zhi (2006) First Hospital of Jilin University Jilin 2 2005.1.24 Li The Second Hospital Affiliated to Zhejiang Zhong Hua Nei Ke Za Zhi (2005) Zhejiang 1 Not reported Zhimin university Medical College Liang Shan Dong Zhong Yi Za Zhi (2011) Xinchang County TCM Hospital Zhejiang 1 2010.6.9 Daming 2007.2 ~ Liang 2009.1 Hu Li Xue Bao (2009) Lishui City Central Hospital Zhejiang 2 Jianli 2007.2 ~ 2009.1 School
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