Carbohydrates and Health Report (ISBN 9780117082847)
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Fructooligosaccharides As Dietary Fibre
FULL ASSESSMENT REPORT AND REGULATORY IMPACT ASSESSMENT A277 - INULIN AND FRUCTOOLIGOSACCHARIDES AS DIETARY FIBRE EXECUTIVE SUMMARY An Application was submitted in July 1995 by Foodsense Pty Ltd on behalf of Orafti Belgium Ltd to the then National Food Authority seeking the following changes to the Australian Food Standards Code to: • permit the declaration of inulin and fructooligosaccharides (FOS) as dietary fibre on food labels; • adopt officially the submitted analytical method for the determination of inulin and FOS; • amend the calculation of carbohydrate by difference by including dietary fibre in the range of macronutrients deducted from 100; and • adopt energy factors for soluble and insoluble dietary fibre (later withdrawn). The Full Assessment of this Application was conducted in the light of the recommendations from the Joint FAO/WHO Expert Consultation on Carbohydrates in Human Nutrition and concludes that the present situation of relying solely on a prescribed method of analysis as the means of defining dietary fibre is unsatisfactory. This Assessment has also drawn on the results of ANZFA’s interactive website opinion survey conducted between January and March 2000, and the advice of the Expert Working Group on a generic definition for dietary fibre. The Authority proposes the following definition of dietary fibre: Dietary fibre is that fraction of the edible part of plants or their extracts, or analogous carbohydrates, that are resistant to digestion and absorption in the human small intestine, usually with complete or partial fermentation in the large intestine. The term includes polysaccharides, oligosaccharides (DP>2) and lignins. Dietary fibre promotes one or more of these beneficial physiological effects: laxation, reduction in blood cholesterol and/or modulation of blood glucose. -
Sensory Evaluation of Ice Cream Made with Prebiotic Ingredients
RURALS: Review of Undergraduate Research in Agricultural and Life Sciences Volume 3 RURALS, Volume 3 -- 2008 Issue 1 Article 4 October 2008 Sensory Evaluation of Ice Cream made with Prebiotic Ingredients Adeline K. Lum Department of Nutrition and Health Sciences, University of Nebraska-Lincoln, [email protected] Julie A. Albrecht Department of Nutrition and Health Sciences, University of Nebraska-Lincoln, [email protected] Follow this and additional works at: https://digitalcommons.unl.edu/rurals Recommended Citation Lum, Adeline K. and Albrecht, Julie A. (2008) "Sensory Evaluation of Ice Cream made with Prebiotic Ingredients," RURALS: Review of Undergraduate Research in Agricultural and Life Sciences: Vol. 3 : Iss. 1 , Article 4. Available at: https://digitalcommons.unl.edu/rurals/vol3/iss1/4 This Article is brought to you for free and open access by the Agricultural Economics Department at DigitalCommons@University of Nebraska - Lincoln. It has been accepted for inclusion in RURALS: Review of Undergraduate Research in Agricultural and Life Sciences by an authorized administrator of DigitalCommons@University of Nebraska - Lincoln. Sensory Evaluation of Ice Cream made with Prebiotic Ingredients Cover Page Footnote The authors would like to thank Laurie Keeler, Senior Manager for Food Technology Transfer of University of Nebraska-Lincoln Food Processing Center for her technical expertise in ice cream production and David Girard, Research Technologist for his assistance during sensory evaluation. Funding for this project was provided by the UCARE program at UNL and the University of Nebraska Agricultural Research Division, supported in part by funds provided through Hatch Act, USDA. Review coordinated by professor Marilynn Schnepf, Department of Nutrition and Health Sciences, University of Nebraska-Lincoln. -
The Comparative Effect on Satiety and Subsequent Energy Intake of Ingesting Sucrose Or Isomaltulose Sweetened Trifle: a Randomized Crossover Trial
nutrients Article The Comparative Effect on Satiety and Subsequent Energy Intake of Ingesting Sucrose or Isomaltulose Sweetened Trifle: A Randomized Crossover Trial Fiona E. Kendall, Olivia Marchand, Jillian J. Haszard and Bernard J. Venn * Department of Human Nutrition, University of Otago, P.O. Box 56, Dunedin 9054, New Zealand; [email protected] (F.E.K.); [email protected] (O.M.); [email protected] (J.J.H.) * Correspondence: [email protected]; Tel.: +64-3-479-5068 Received: 25 September 2018; Accepted: 13 October 2018; Published: 15 October 2018 Abstract: The effect that blood glucose concentration has on feelings of satiety is unclear. Our aims were to assess satiety and subsequent energy intake following the ingestion of trifle sweetened with sucrose or isomaltulose whilst measuring plasma glucose concentration to confirm glycemic differences between trifles. Seventy-seven healthy adults participated in a double-blind crossover trial where trifle sweetened with sucrose or isomaltulose was consumed on separate days with a two-week washout. Blood was sampled at the baseline, 1 and 2 h postprandially, and satiety assessed using visual analogue scales (VAS). Weighed diet records were taken on test days. A statistically significant difference in blood glucose concentration between trifles was found at 60 min following consumption, with the isomaltulose trifle having a 0.69 mmol/L (95% confidence interval (CI): −1.07, −0.31) lower concentration when compared with the sucrose trifle. Mean satiety response by area-under-the-curve (AUC) was not significantly different between trifles. Mean (SD) appetite scores for the sucrose and isomaltulose trifles were 4493 (2393) and 4527 (2590) mm·min, respectively, with a between trifle difference of −9 (95% CI: −589, 572) mm·min. -
FDA Finalizes Allulose Guidance and Requests Information on Other Sugars Metabolized Differently Than Traditional Sugars
FDA Finalizes Allulose Guidance and Requests Information on Other Sugars Metabolized Differently Than Traditional Sugars October 19, 2020 Food, Drug, and Device FDA has taken two notable actions regarding the sugars declaration in the Nutrition Facts Label (NFL) and Supplement Facts Label (SFL). On Friday, the agency released a final guidance regarding the declaration of allulose, confirming that this monosaccharide need not be included in the declaration of “Total Sugars” or “Added Sugars,” though it must be included in the “Total Carbohydrates” declaration in the NFL. Today, FDA published a Federal Register notice requesting information about and comments on the nutrition labeling of other sugars that are metabolized differently than traditional sugars. We briefly summarize both documents below to help inform stakeholder comments on the notice, which are due to FDA by December 18, 2020. Allulose Final Guidance Allulose, or D-psicose, is a monosaccharide that can be used as a substitute for traditional sugar in food and beverage products. For purposes of nutrition labeling, FDA has generally 1 defined nutrients based on their chemical structure.0F Accordingly, when FDA updated its NFL and SFL regulations in 2016, the agency reiterated the definition of “Total Sugars” as the sum of 2 all free monosaccharides and disaccharides (e.g. glucose, fructose, and sucrose).1F FDA also added to these regulations a definition of “Added Sugars” – sugars added during the processing 3 of food, or packaged as such – and required their declaration in the NFL and SFL.2F Although the agency recognized that there are sugars that are metabolized differently than traditional sugars, FDA did not make a determination at that time as to whether allulose should be excluded from “Total Carbohydrate,” “Total Sugars,” or “Added Sugars” Declarations. -
Food & Nutrition Journal
Food & Nutrition Journal Oku T and Nakamura S. Food Nutr J 2: 128. Review article DOI: 10.29011/2575-7091.100028 Fructooligosaccharide: Metabolism through Gut Microbiota and Prebiotic Effect Tsuneyuki Oku*, Sadako Nakamura Institute of Food, Nutrition and Health, Jumonji University, Japan *Corresponding author: Tsuneyuki Oku, Institute of Food, Nutrition and Health, Jumonji University, 2-1-28, Sugasawa, Niiza, Saitama 3528510, Japan. Tel: +81 482607612; Fax: +81 484789367; E-mail: [email protected], t-oku@jumonji-u. ac.jp Citation: Oku T and Nakamura S (2017) Fructooligosaccharide: Metabolism through Gut Microbiota and Prebiotic Effect. Food Nutr J 2: 128. DOI: 10.29011/2575-7091.100028 Received Date: 20 March, 2017; Accepted Date: 06 April, 2017; Published Date: 12 April, 2017 Abstract This review aims to provide the accurate information with useful application of Fructooligosaccharide (FOS) for health care specialists including dietician and physician, food adviser and user. Therefore, we described on metabolism through gut microbiota, physiological functions including prebiotic effect and accelerating defecation, practical appli- cation and suggestions on FOS. FOS is a mixture of oligosaccharides what one to three molecules of fructose are bound straightly to the fructose residue of sucrose with β-1,2 linkage. FOS which is produced industrially from sucrose using enzymes from Aspergillus niger, is widely used in processed foods with claimed health benefits. But, FOS occurs natu- rally in foodstuffs including edible burdock, onion and garlic, which have long been part of the human diet. Therefore, eating FOS can be considered a safe food material. FOS ingested by healthy human subjects, does not elevate the blood glucose and insulin levels, because it is not digested by enzymes in the small intestine. -
The Food Lawyers® Respectfully Request That FDA Implements the Following
December 7, 2020 Dockets Management Staff (HFA-305) Filed Electronically Food and Drug Administration https://www.regulations.gov Re: Sugars Metabolized Differently than Traditional Sugars (FDA-2020-N-1359) Ladies and Gentlemen: One Page Executive Summary FDA’s seeks information to “… promote the public health and help consumers make informed dietary decisions” regarding sugars that are metabolized differently than traditional sugars. Given the nation’s battles with diabetes and obesity, and the benefits that non-traditional sugars can offer in these battles, the Agency’s stated public policy goal goes to the very heart of American consumers’ health. This laudatory public policy’s realization is complicated by a lack of consumer awareness of how some sugars are metabolized differently than others. In an effort to answer the questions posed by the Agency regarding the treatment of Sugars that Are Metabolized Differently Than Traditional Sugars, we suggest that the Agency adapt a mechanism that will seek to harmonize the public policy of promoting public health with consumers’ lack of awareness of sugars that are metabolized differently than sucrose. In particular, we suggest that FDA should consider the following: 1. Establish a new category of sugars called Rare Sugars that exhibit the following characteristics: a. Are naturally occurring b. Impart a sweet taste that is at least 50% the sweetness of sucrose c. 2.0 kcal/g or less. d. Resulting pH of 6.0 or greater of dental plaque after consumption. e. No or low glycemic response. f. No or low insulinemic response. 2. Exclude Rare Sugars from “Total Sugars” and “Added Sugars” declarations to stimulate their deployment by industry and consumption by the public. -
Production, Purification and Fecal Fermentation of Fructooligosaccharide by Ftase from Jerusalem Artichoke
International Food Research Journal 24(1): 134-141 (February 2017) Journal homepage: http://www.ifrj.upm.edu.my Production, purification and fecal fermentation of fructooligosaccharide by FTase from Jerusalem artichoke 1*Wichienchot, S., 1Prakobpran, P., 2Ngampanya, B. and 2Jaturapiree, P. 1Interdisciplinary Graduate School of Nutraceutical and Functional Food, The Excellent Research Laboratory for Cancer Molecular Biology, Prince of Songkla University, Hat Yai, Songkhla, Thailand 90112 2Department of Biotechnology, Faculty of Engineering and Industrial Technology, Silpakorn University, Nakorn Pathom, Thailand 73000 Article history Abstract Received: 11 August 2015 Fructooligosaccharides (FOS) has been used as prebiotic that serves as a substrate for microflora Received in revised form: in the large intestine. FOS are produced by fructosyltransferase (FTase) derived from some 15 February 2016 Accepted: 17 March 2016 plants such as Jerusalem artichoke, chicory, asparagus, banana, dragon fruit and onion. It was found that Jerusalem artichoke cultured in tropical region for 3-5 months showed good source of FTase. It had the highest crude enzyme activity of 0.253±0.003 U/ml. Optimal conditions for purification of FTase by chromatography techniques with anion exchangers showed the Keywords highest specific activity which increased from 1.411 to 2.240 U/ml. Optimum conditions Fructooligosaccharide for production of FOS were 20% sucrose, reaction time of 96 h and 1 U/ml FTase. It was Jerusalem artichoke found that highest FOS (35%) consisted of 27.5% 1-kestose (DP 2) and 7.5% nystose (DP 3). Fecal fermentation Fructooligosaccharide was further purified by yeast fermentation using 2.5% Saccharomyces Prebiotic cerevisiae TISTR5019 for 36 h. -
Canadian Diabetes Association National Nutrition Committee Technical Review: Non-Nutritive Intense Sweeteners in Diabetes Management
non-nutritive intense sweetener use 385 Canadian Diabetes Association National Nutrition Committee Technical Review: Non-nutritive Intense Sweeteners in Diabetes Management Réjeanne Gougeon1 PhD, Mark Spidel2 MSc, Kristy Lee3 BSc, Catherine J. Field3 PhD 1McGill Nutrition and Food Science Centre, Montreal, Quebec, Canada 2Health and Social Services, Montague, Prince Edward Island, Canada 3Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada ABSTRACT RÉSUMÉ The current Canadian Diabetes Association Clinical Practice Selon les Lignes directrices de pratique clinique actuelles de Guidelines for the Prevention and Management of Diabetes l’Association canadienne du diabète, jusqu’à 10 % des calo- in Canada state that up to 10% of daily calories can be ries consommées chaque jour peuvent provenir des sucres. derived from sugars. However, individuals with diabetes may Cependant, les personnes atteintes de diabète peuvent aussi also be relying on alternative, low-calorie sweetening agents se servir de succédanés contenant peu ou pas de calories et (providing little or no calories along with sweet taste) to con- ayant le goût du sucre pour limiter leur consommation de trol carbohydrate intake, blood glucose, weight and dental glucides, maîtriser leur glycémie et leur poids et éviter les health. Most low-calorie sweeteners, sometimes called caries dentaires. La plupart des édulcorants à faible teneur en intense or artificial sweeteners, are classified and regulated as calories, parfois appelés édulcorants de synthèse ou édulco- food additives with set acceptable daily intake (ADI) levels. rants artificiels, sont considérés comme des additifs alimen- The Health Canada Health Products and Food Branch taires et leur apport quotidien est par conséquent réglementé. -
Metabolic, Hormonal and Performance Effects of Isomaltulose Ingestion Before Prolonged Aerobic Exercise: a Double-Blind, Randomised, Cross-Over Trial Hannah L
Notbohm et al. Journal of the International Society of Sports Nutrition (2021) 18:38 https://doi.org/10.1186/s12970-021-00439-z RESEARCH ARTICLE Open Access Metabolic, hormonal and performance effects of isomaltulose ingestion before prolonged aerobic exercise: a double-blind, randomised, cross-over trial Hannah L. Notbohm1, Joshua F. Feuerbacher1, Finn Papendorf1, Nils Friese1, Mats W. Jacobs1, Hans-Georg Predel2, Jonas Zacher2, Wilhelm Bloch1 and Moritz Schumann1* Abstract Background: Isomaltulose has been discussed as a low glycaemic carbohydrate but evidence concerning performance benefits and physiological responses has produced varying results. Therefore, we primarily aimed to investigate the effects of isomaltulose ingestion compared to glucose and maltodextrin on fat and carbohydrate oxidation rates, blood glucose levels and serum hormone concentrations of insulin and glucose-dependent insulinotropic polypeptide (GIP). As secondary aims, we assessed running performance and gastrointestinal discomfort. Methods: Twenty-one male recreational endurance runners performed a 70-min constant load trial at 70% maximal running speed (Vmax), followed by a time to exhaustion (TTE) test at 85% Vmax after ingesting either 50 g isomaltulose, maltodextrin or glucose. Fat and carbohydrate oxidation rates were calculated from spiroergometric data. Venous blood samples for measurement of GIP and insulin were drawn before, after the constant load trial and after the TTE. Capillary blood samples for glucose concentrations and subjective feeling of gastrointestinal discomfort were collected every 10 min during the constant load trial. (Continued on next page) * Correspondence: [email protected] 1Department of Molecular and Cellular Sports Medicine, German Sport University Cologne, Am Sportpark Müngersdorf 6, 50933 Cologne, Germany Full list of author information is available at the end of the article © The Author(s). -
Tagatose and Milk Allergy
ALLERGY Net Tagatose and milk allergy S. L. Taylor*, D. M. Lambrecht, S. L. Hefle Key words: allergy; cows' milk; tagatose. Tagatose is a new food ingredient being used as a reduced-calorie sweetener in foods and bever- ages. Tagatose is a six-carbon ke- Tagatose does not tose sugar found contain milk residues. naturally in some dairy products and in tropical date trees. As tagatose is incompletely absorbed, it provides only 1.5 cal/g as contrary to 4 cal/g for sucrose. Tagatose has approximately the same sweetness as sucrose. Recently, a manufacturing process for tagatose has been developed allowing the production of increased quantities of tagatose. Tagatose has been affirmed as Generally Recognized as Safe (GRAS) in the US and is approved for use in foods and beverages in the US, Korea, Australia and New Zealand. Tagatose is a unique ketose sugar manufactured by the isomerization of galactose. The galactose involved in the manufacturing of tagatose is derived from lactose, the disaccharide found in the whey fraction of milk. Lactose is known to contain residual milk proteins including several of the major cowsÕ milk allergens, principally b-lactoglobulin and a-lactalbumin from whey, on occasion (1). Consequently, some questions were raised about the potential allergenicity of tagatose. Although lactose often contains resid- ual milk allergens, tagatose is much less likely to contain any milk allergens based upon knowledge of the process used to 412 ALLERGY Net produce tagatose. The steps involved in at sensitivity levels of 2.5 p.p.m. (mg/ the manufacturing of tagatose from kg) for casein and 1.0 p.p.m. -
High-Calorie, High-Protein Diet with Fiber for Patients with Diabetes Contains Isomaltulose, Which Contributes to Better Glycaemic Control
High-Calorie, High-Protein Diet with fiber for patients with diabetes Contains isomaltulose, which contributes to better glycaemic control. For tube feeding. Calorie density: 1.20 Kcal/ml P/CH/Fat/Fiber = 22/40/35/3 Osmolarity: 315 mOsmol/l 50 NEUTRAL FLAVOUR 12X500 ml C.I. 504958 Vanilla Scent NEUTRAL FLAVOUR SUITABLE FOR CELIAC PATIENTS High-Calorie, High-Protein Diet High-Calorie, High-Protein 51 NUTRITION FACTS 100 ml 500 ml VITAMINS 100 ml 500 ml Energy 503/120 2515/600 kJ/kcal Vitamin A 64 320 µg-RE Total Fat 4.7 23.3 g Vitamin D 0.6 3 µg Of which: Saturated 1.04 5.2 g Vitamin K 6 30 µg MCT 0.7 3.5 g Vitamin C 6.4 32 mg Monounsaturated 2.3 11.7 g Thiamin 0.09 0.4 mg Polyunsaturated 1.1 5.6 g Riboflavin 0.1 0.5 mg ω-3 0.33 1.65 g Vitamin B6 0.1 0.5 mg ω-6 0.75 3.75 g Niacin 1.3 6.5 mg NE ω-6/ω-3 ratio: 2.27/1 Folic acid 16 80 µg Total Carbohydrates 12 60 g Vitamin B12 0.2 1 µg Of which: Sugars 2.5 12.5 g Pantothenic acid 0.5 2.5 mg Lactose 0.28 1.4 g Biotin 4 20 µg Dietary Fiber 1.8 9 g Vitamin E 1 5 mg α-TE Protein 6.6 33 g Inositol 15 75 mg Salt 0.28 1.4 g Choline 15 75 mg MINERALS 100 ml 500 ml Osmolaridad: 315 mOsmol/l Osmolality: 389 mOsm/kg Sodium 111 555 mg Viscosidad: 55.6 cps OH Chloride 45 225 mg It contains Isomaltulose (glucose O HO Isomaltulose Potassium 133 665 mg disaccharide and fructose: 1.2 g / 100 ml) HO OH Calcium 110 550 mg Low lactose content (not suitable for O OH Phosphorous 95 475 mg persons with galactosemia) O HO Magnesium 20 100 mg Low salt content (0.28 g / 100 ml) Iron 1.1 5.6 mg Gluten free HO OH Zinc 0.8 4 mg Without sucrose Copper 0.08 0.4 mg Vanilla scent to soften the effects of possible reflux Iodine 12 60 µg Selenium 4.4 22 µg NUTRITIONAL INFORMATION: Manganese 0.16 0.8 mg The standard dose (1,500 ml/day) contains 99 g of protein, Chromium 18 90 µg 180 g of carbohydrates, 69.9 g of fat, 27 g of fiber, 1,800 Molybdenum 4.2 21.1 µg kcal and provides 100% of the RDA (Recommended Dietary Fluoride 0.23 1.15 mg Allowance) of vitamins and minerals. -
Final Assessment Report Application A578
3-07 23 May 2007 FINAL ASSESSMENT REPORT APPLICATION A578 ISOMALTULOSE AS A NOVEL FOOD For information on matters relating to this Assessment Report or the assessment process generally, please refer to http://www.foodstandards.gov.au/standardsdevelopment/ Executive Summary FSANZ received an application from PALATINIT GmbH on 27 April 2006 to amend Standard 1.5.1 – Novel Foods, of the Australia New Zealand Food Standards Code (the Code) to approve the use of isomaltulose as a novel food. Isomaltulose is a disaccharide comprised of glucose and fructose joined by an α-1,6 glycosidic bond. Isomaltulose is naturally present at very low levels in sugar cane juice and honey. Under the current food standards, novel foods are required to undergo a pre-market safety assessment, as per Standard 1.5.1 - Novel Foods. Isomaltulose is considered to be a non- traditional food because there is no history of significant human consumption in Australia or New Zealand. Based on the potential for increased consumption patterns if isomaltulose were used as a food ingredient, and the fact that the safety of isomaltulose had not yet been determined, isomaltulose is considered to be a novel food and is accordingly considered under Standard 1.5.1. The objective of this assessment is to determine whether it is appropriate to amend the Code to permit the use of isomaltulose as a novel food. Such an amendment would need to be consistent with the section 10 objectives of the FSANZ Act. The safety assessment and dietary exposure assessment indicate that isomaltulose poses no public health and safety concern to the vast majority of consumers.