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1. What Enalapril/Lercanidipine Krka Is and What It Is Used

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1. What Enalapril/Lercanidipine Krka Is and What It Is Used PL. ENALAPRIL/LERCANIDIPINE KRKA 10 MG/10 MG IE first page IIIIIfflI Package leaflet: Information for the user 1. What Enalapril/Lercanidipine Krka is - obstruction to the flow of blood from the left ventricle • if you have renal problems (including kidney transplantation); - temsirolimus, sirolimus, everolimus and other medicines • potassium-sparing diuretics (e.g. triamterene, amiloride), • a medicine for ulcers and heartburn called cimetidine at of the heart, including a narrowing of the aorta (aortic • if you have abnormally increased levels of a hormone belonging to the class of mTOR inhibitors (used to avoid potassium supplements or medicines containing daily doses of more than 800 mg. and what it is used for stenosis); called aldosterone in your blood (primary aldosteronism); rejection of transplanted organs and for cancer), potassium (including dietary salt substitutes), other drugs • medicines which are most often used to treat diarrhoea Enalapril/Lercanidipine Krka Enalapril/Lercanidipine Krka is a fixed combination of an - chest discomfort occurring at rest or becoming worse • if you have liver problem; - racecadotril (used to treat diarrhoea), which can increase potassium in your body (such as (racecadotril) or avoid rejection of transplanted organs 10 mg/10 mg film-coated tablets ACE-inhibitor (enalapril) and a calcium channel blocker or happening more often (unstable angina pectoris); • if you have a blood problem, such as low or lack of white - vildagliptin (a medicine used to treat diabetes). heparin, a medicine used to thin blood to prevent clots; (sirolimus, everolimus, temsirolimus and other medicines (lercanidipine), two medicines that lower blood pressure. - within one month after suffering a heart attack blood cells (leucopenia, agranulocytosis), low platelet If you are about to have a procedure trimethoprim and co-trimoxazole also known as belonging to the class of mTOR inhibitors). See section enalapril maleate/lercanidipine hydrochloride Enalapril/Lercanidipine Krka is used for the treatment of (myocardial infarction). count (thrombocytopenia or a decreased number of red If you are about to have any of the following, tell your trimethoprim/sulfamethoxazole, for infections caused by “Warnings and precautions”. high blood pressure (hypertension) in patients whose • if you have severe liver or kidney problems, or if you are blood cells) (anaemia); doctor that you are taking Enalapril/Lercanidipine Krka: bacteria; and ciclosporin, an immunosuppressant Your doctor may need to change your dose and/or to take Read all of this leaflet carefully before you start taking blood pressure is not adequately controlled by undergoing dialysis; • if you have collagen vascular diseases (e.g. lupus • any surgery or receive anaesthetics (even at the dentist); medicine used to prevent organ transplant rejection); other precautions: this medicine because it contains important lercanidipine 10 mg alone. Enalapril/Lercanidipine Krka • if you use medicines such as: erithematosus, rheumatoid arthritis or scleroderma); • a treatment to remove cholesterol from your blood called • other medicines that lower blood pressure, such as • if you are taking an angiotensin II receptor blocker (ARB) information for you. should not be used for initial treatment of hypertension. - antifungals (e.g. ketoconazole, itraconazole); • if you are a black patient you should be aware that black “LDL apheresis”; angiotensin II receptor-blockers, diuretics (water pills) or or aliskiren (see also information under the headings “Do • Keep this leaflet. You may need to read it again. - macrolide antibiotics (e.g. erythromycin, patients are at increased risk of allergic reactions with • a desensitization treatment, to lower the effect of any a medicine called aliskiren; not take Enalapril/Lercanidipine Krka” and “Warnings and • If you have any further questions, ask your doctor or 2. What you need to know before you take troleandomycin); swelling of the face, lips, tongue or throat with difficulty in allergy to bee or wasp stings. • lithium (a medicine used to treat a certain kind of depression); precautions”). pharmacist. - antivirals (e.g. ritonavir). swallowing or breathing when taking ACE-inhibitors; You must tell your doctor if you think you are (or might • medicines for depression called ‘tricyclic antidepressants’; Enalapril/Lercanidipine Krka Enalapril/Lercanidipine Krka with food, drink and • This medicine has been prescribed for you only. Do not • if you are taking another drug called cyclosporin or • if you suffer from diabetes mellitus; become) pregnant or breastfeeding (see pregnancy, • medicines for mental problems called ‘antipsychotics’; alcohol pass it on to others. It may harm them, even if their signs Do not take Enalapril/Lercanidipine Krka ciclosporin (used after transplants to prevent organ rejection); • if you develop a persistent dry cough; breastfeeding and fertility section). • non-steroidal anti-inflammatory drugs, including of illness are the same as yours. • if you are allergic to enalapril or lercanidipine or any of Enalapril/Lercanidipine Krka should be taken at least - PMS-433U-KRKA • together with grapefruit or grapefruit juice. • if you are taking potassium supplements, potassium- COX-2-inhibitors (medicines that reduce inflammation • If you get any side effects, talk to your doctor or the other ingredients of this medicine (listed in section 6); Children and adolescents 15 minutes before a meal. • if you have taken or are currently taking sacubitril/ sparing agents, or potassium-containing salt substitutes; Do not give this medicine to children and adolescents and can be used to help relieve pain); pharmacist. This includes any possible side effects not • if you have ever had an allergic reaction to a type of Alcohol can increase the effect of Enalapril/Lercanidipine valsartan, a medicine used to treat a type of long-term • if you have an intolerance to certain sugars (lactose); under the age of 18 years as there is no information on if it • certain pain or arthritis medicines including gold therapy listed in this leaflet. See section 4. medicines similar to those contained in Enalapril/ Krka. You are therefore advised either to consume no (chronic) heart failure in adults, as the risk of • if you are taking any of the following medicines used to works and if it is safe. (especially with intravenous administration); Lercanidipine Krka, i.e. medicines called ACE-inhibitors treat high blood pressure: • certain cough and cold medicines and weight reducing alcohol or to strictly limit your alcohol intake. angioedema (rapid swelling under the skin in an area Other medicines and Enalapril/Lercanidipine Krka What is in this leaflet or calcium channel blockers; - an angiotensin II receptor blocker (ARBs) (also known as medicines which contain something called a Enalapril/Lercanidipine Krka should not be taken with such as the throat) is increased. Enalapril/Lercanidipine Krka must not be taken with certain 1. What Enalapril/Lercanidipine Krka is and what it is used • if you have ever developed angioedema (oedema of the sartans - for example valsartan, telmisartan, irbesartan), ‘sympathomimetic agent’; grapefruit or grapefruit juice. for face, lips, mouth, tongue or throat) which caused medications. Warnings and precautions in particular if you have diabetes-related kidney problems; • medicines for diabetes (including insulin and oral 2. What you need to know before you take Enalapril/ difficulty in swallowing or breathing (angioedema) after Tell your doctor or pharmacist if you are taking, have recently Pregnancy, breastfeeding and fertility Talk to your doctor or pharmacist before taking Enalapril/ - aliskiren. antidiabetic medicines such as vildagliptin); Lercanidipine Krka taking a type of medicine called ACE-inhibitors, or when taken or might take any other medicines, including medicines Lercanidipine Krka: Your doctor may check your kidney function, blood • astemizole or terfenadine (medicines for allergies); Pregnancy and fertility 3. How to take Enalapril/Lercanidipine Krka the reason why was not known or it was inherited; • if you have low blood pressure (you may notice this as obtained without a prescription. This is because when You must tell your doctor if you think you are (or might pressure, and the amount of electrolytes (e.g. Enalapril/Lercanidipine Krka is taken simultaneously with • amiodarone or quinidine (medicines to treat a fast heart beat); 4. Possible side effects • if you have diabetes or impaired kidney function and you faintness or dizziness, especially when standing); become) pregnant. Your doctor will normally advise you to potassium) in your blood at regular intervals. certain other medicines, the effect of Enalapril/Lercanidipine • phenytoin or carbamazepine (medicines for epilepsy); 5. How to store Enalapril/Lercanidipine Krka are treated with a blood pressure lowering medicine • if you have been very sick (excessive vomiting) or have stop taking Enalapril/Lercanidipine Krka before you 6. Contents of the pack and other information containing aliskiren; See also information under the heading “Do not take Krka or of the other medicine may be intensified or weakened, • rifampicin (a drug for the treatment of tuberculosis); had diarrhoea recently, or are dehydrated; become pregnant or as soon as you know you are • if you are more than 3 months pregnant. (it is also better Enalapril/Lercanidipine Krka”. or certain side effects may occur more frequently. • digoxin (a medicine to treat heart problems);
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