FGFR1OP (Human) Recombinant Protein (P01)

Catalog # : H00011116-P01 規格 : [ 10 ug ] [ 25 ug ] List All

Specification Application Image

Product Human FGFR1OP full-length ORF ( AAH11902, 1 a.a. - 379 a.a.) Enzyme-linked Immunoabsorbent Assay Description: recombinant protein with GST-tag at N-terminal. Western Blot (Recombinant Sequence: MAATAAAVVAEEDTELRDLLVQTLENSGVLNRIKAELRAAVFLALEEQEK protein) VENKTPLVNESLRKFLNTKDGRLVASLVAEFLQFFNLDFTLAVFQPETST LQGLEGRENLARDLGIIEAEGTVGGPLLLEVIRRCQQKEKGPTTGEGAL Antibody Production DLSDVHSPPKSPEGKTSAQTTPSKKANDEANQSDTSVSLSEPKSKSSLH LLSHETKIGSFLSNRTLDGKDKAGLCPDEDDMEGDSFFDDPIPKPEKTY Protein Array GLRNEPRKQAGSLASLSDAPPLKSGLSSLAGAPSLKDSESKRGNTVLKD LKLISDKIGSLGLGTGEDDDYVDDFNSTSHRSEKSEISIGEEIEEDLSVEID DINTSDKLDDLTQDLTVSQLSDVADYLEDVA

Host: Wheat Germ (in vitro)

Theoretical MW 67.43 (kDa):

Preparation in vitro wheat germ expression system Method:

Purification: Glutathione Sepharose 4 Fast Flow

Quality Control 12.5% SDS-PAGE Stained with Coomassie Blue. Testing:

Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Storage Store at -80°C. Aliquot to avoid repeated freezing and thawing. Instruction:

Note: Best use within three months from the date of receipt of this protein.

MSDS: Download

Datasheet: Download

Publication Reference 1. Fibroblast growth factor receptor 1 oncogene partner as a novel prognostic biomarker and therapeutic target for lung cancer. Page 1 of 2 2016/5/23 Mano Y, Takahashi K, Ishikawa N, Takano A, Yasui W, Inai K, Nishimura H, Tsuchiya E, Nakamura Y, Daigo Y.Cancer Sci. 2007 Dec;98(12):1902-13. Epub 2007 Sep 18.

Applications Enzyme-linked Immunoabsorbent Assay

Western Blot (Recombinant protein)

Antibody Production

Protein Array

Gene Information

Entrez GeneID: 11116

GeneBank BC011902 Accession#:

Protein AAH11902 Accession#:

Gene Name: FGFR1OP

Gene Alias: FOP

Gene FGFR1 oncogene partner Description:

Omim ID: 605392

Gene Ontology: Hyperlink

Gene Summary: This gene encodes a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine- rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq

Other OTTHUMP00000017612,OTTHUMP00000017613,fibroblast growth Designations: factor receptor 1 oncogene partner

Related Disease Colitis, Ulcerative Crohn Disease Crohn's disease Genetic Predisposition to Disease Tobacco Use Disorder Vitiligo

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