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Erythrocytes take up oxygen and release carbon dioxide AL1A1 ADH6ADHXADH7 ADH1G ADH1B ADH4 AL1B1 Cyclin E associated events during G1/S transition FRS-mediated FGFR4 signaling ADH1A CP2E1CP2B6 CP2A6 CP2CJCP2C8 CP2AD CP2C9 CP2D6 Pyrimidine salvageKHK TRP channels AL1A3 CP2J2Fanconi Anemia Pathway AL1A2 I23O1KMO Synthesis of bile acids and bile HYESsalts via 27-hydroxycholesterol AADATKYNUT23O Cobalamin (Cbl, vitamin B12) transport and metabolism CP3A5 ARMS-mediated activation Syndecan interactionsCP3A4 CP1A2 Tryptophan catabolism PANK3PANK2 Abacavir metabolism PANK1 Advanced glycosylation endproduct receptor signaling KCNK3 KCNK9 Loss of ALDH2proteins required for interphase microtubule organization from the centrosome XAV939 inhibits tankyrase, stabilizing AXIN Phase 2 - plateau phase KCNK2 Orc1 removal from chromatin Mineralocorticoid biosynthesis S22A6 S22ABS22AC CP26A Truncations of AMER1 destabilize the destruction complex Cytosolic sensorsPurine ribonucleoside of pathogen-associated monophosphate DNA biosynthesis ST1E1 UMPSPYRD CholineCGAT1 catabolism TPST2ST1A1 Separation ofTPH1 Sister Chromatids Methionine INMTsalvage pathway Phase 4 - restingHPPD membrane potential Classical antibody-mediatedKCNJ4 complement activation Phase I - Functionalization of compounds KCNJ2 Cargo recognition for clathrin-mediatedBODG endocytosis ENTP3ENTP1 CP1B1 ADAL ENTP2 CD38 Costimulation by the CD28 family N-glycan trimming in the ER and Calnexin/Calreticulin cycle METK2TPMT BHMT1 PGH1 Metalloprotease DUBs Retrograde neurotrophin signalling DHSO Caspase-mediated cleavage of cytoskeletal proteins Stimuli-sensing channelsCholesterol biosynthesis via lathosterol CP4F3 Metabolism of ingested SeMet, Sec, MeSec into H2Se BHMT2 KCNJ3KCNJ9 SC6A1 Inactivation,CP1A1 recoveryEicosanoid and ligand-bindingregulation of theTHAS receptors phototransduction cascade S6A13 Activation of E2F1 target genesKCNJ5KCNJ6 at G1/S S6A11 SL9A2 Vitamin C (ascorbate) metabolism GABA synthesis, release,ICMT reuptake and degradation COMT Acrosome Reaction FRS-mediated FGFR3 signaling Smooth Muscle Contraction ACRO DNASC6A3 replication initiation Defective MTR causes methylmalonicDefective LFNG causes aciduria5NTD SCDO3 and homocystinuria type cblG MethylationMGMT CBR1PTGES AK1A1 COX reactions Glutamate Neurotransmitter Release Cycle SC6A9SC6A5 METH SAHHMyD88:Mal cascade initiatedSC6A2 on plasma membrane Purine salvage Vpu mediated ASAP1degradation of CD4 Synthesis of PIPs at the plasma membrane Hedgehog 'on' state Erythrocytes takeDHB2 up carbon dioxide and release oxygen EPH-EphrinMA1B1 signaling SC6A6 UD11 GGT1 UD14 ADAADK DHI1 SL9A1 HPGDS HPRT KCRM DHI2 EntryEnzymatic of Influenza degradation Virion into of dopamineHost Cell via by Endocytosis COMT ALDR Stabilization of p53 PPBN Protein methylation DHB1 Glucocorticoid biosynthesisCBPMXPP2 AOC2AOC3EST1 Transport of the SLBP DependantUD13 Mature mRNAPPBT Glucagon-likeS15A1 Peptide-1 (GLP1) regulates insulin secretion EST2 AK1C3 Digestion of dietary carbohydrate ACATN UD18UD16 S15A2 HYEPAL3A1NQO2 Purine catabolism AOFB Polymerase switchingUDB15UD110 on the C-strand of the telomere PGDH UD2B7UD17 PTGIS TYPH Retinoid cycle disease events UPP1 Binding of TCF/LEF:CTNNB1 to target gene promoters LA GSTM1GSTM2 Amino acid synthesis and interconversion (transamination) RNA Polymerase II Transcription Initiation And Promoter Clearance LIPP GSTA1 AAAT RNA Polymerase II Transcription Pre-Initiation And Promoter Opening Phase 3 - rapid repolarisation TGFBR2 Kinase Domain Mutants in Cancer CP19A ENPP1 DCK 3BHS2 Late Phase of HIV Life Cycle Telomere C-strand synthesis initiation Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) Endogenous sterols betaKlotho-mediated ligand binding CETP ENPP2 SO2A1 PAR14PARP4 SIA4A Viral mRNA TranslationRET4 Beta-oxidationPRC2 methylatesof pristanoyl-CoA histonesCP17A andC11B1 DNA SO2B1 PARP8 Glucuronidation VPS4B DHB4 Synthesis of active ubiquitin:PAR10PARP6 roles of E1 and E2 enzymes SIAT1 Regulation of cholesterol biosynthesis by SREBP (SREBF) PDE6D TESK1 C11B2 Viral RNP Complexes in the Host Cell Nucleus STS PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases Arachidonic acid metabolism FADS2 The activation of arylsulfatases LOX12 DCMC LIPE NEUR4 DEx/H-box helicases activate type I IFN and inflammatory cytokines production Transport of Mature mRNA Derived from an IntronlessN-Glycan Transcript antennae elongation LPHSUIS NANP HEXA S5A1Alpha-defensins GABA A (rho) receptor activation AMYPCHIA PPBI Anchoring of the basal body to theS5A2 plasma membrane AMY1 AK1BA CP24A DHB3 Cross-presentationHuR (ELAVL1) of soluble binds and exogenous stabilizes mRNA antigens (endosomes) AOFA GABR1HDACs deacetylate histones AK1C1 KITM TS101 GABR2 AK1C2 AK1C4 NEUR2 TSPO SO1A2 S27A5 JNK (c-Jun kinases) phosphorylation and activationNEUR3 mediated by activated human TAK1 FOLR2 Ligand-gatedInterleukin-6 ion channel transportfamily signaling SO1B3 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) SO1B1 DigestionSHC-mediatedNGF processing cascade:FGFR4 Synthesis of IP3 and IP4 in the cytosol MHC class II antigen presentation RET signaling Josephin domainMOGT2 DUBs SC5A1 MBL2 Response to elevatedATS13 platelet cytosolicGSTO1 Ca2+ ASMGBA3GBA2 Pyrimidine biosynthesis Breakdown of the nuclear lamina Inhibition of Signaling by OverexpressedSynthesis of EGFR PIPs in the nucleus AHR SIAT6 CEGTASAH2 Metabolism of ingested H2SeO4 and H2SeO3 into H2Se LDL clearance XCT Class C/3 (Metabotropic glutamate/pheromone receptors) ABCBB KKCC1 Transport of vitamins, nucleosides, and related molecules NRAM2 Synthesis of bile acids and bile salts via 24-hydroxycholesterol Defective AVP causes neurohypophyseal diabetesSynthesis insipidus and processing (NDI) of ENV and VPU S40A1 Elevation of cytosolic Ca2+ levelsSC5A2 Nuclear Receptor transcription pathway BMR1ABMR1B SC5A4 DGAT2 ACVL1BMPR2 NTCPNTCP2 Glycolysis TF C1R alpha-linolenic acid (ALA) metabolism HEXB S22A1 CAH2 CREB phosphorylation through the activation of CaMKII C1S Pyrimidine catabolism AL5AP PNPHS22A2 XDH ER-PhagosomeCAH4 pathway Protein repair Metabolism of polyamines PA2GDPA2G5 ERKs are inactivated Cell-extracellularSynthesis of matrixbile acids interactions and bile salts PA2GX ReceptorClathrin-mediated Mediated endocytosisMitophagy SCD5 LX15B PA21B ERAP1ERAP2 PCFT Signaling by activated point mutantsTNNT2 of FGFR3 Acyl Acylchain chain remodelling remodelling of PG of PE DGLAABHD6 LGULLDHA MOT4MOT1 Eukaryotic Translation Termination TNNC1 Acyl chain remodellingPA2G3 of PI ABD12 LDHBFADS1 FAS Interaction between L1 and Ankyrins IRF3 mediated activation of type 1 IFN PA2GA DHB7 RecruitmentBPL1 of mitotic centrosome proteinsInlA-mediated and complexes entry of Listeria monocytogenes into host cells BGAL S27A2 CTRC UD19 Cytosolic sulfonationSYMC of small molecules ABCG2 3MG Activation of Matrix Metalloproteinases Calnexin/calreticulinApoptotic cycle execution phase Scavenging by Class A Receptors ATS1 Meiotic synapsis Sema4D induced cell migrationSYK and growth-cone collapse Reuptake of GABA Activation of CaMK IV DefectiveDefective SLCO1B1 SFTPA2 causes causes hyperbilirubinemia, idiopathicVitamin B2 pulmonary (riboflavin) Rotor fibrosis metabolism type (IPF) (HBLRR)PUR2PUR9 ATS5ATS4 Stimulation of the cell death response by PAK-2p34 CAH7CAH13 Fatty acids Synthesis of 12-eicosatetraenoic acid derivatives S19A1 Acyl chain remodelling of PC CAH5A ELOV6 YAP1- and WWTR1 (TAZ)-stimulated gene expression FA9 Acyl chain remodeling of DAG and TAG GRIK2 SYTC CAH6CAH12CAH5B CP51A ARNT Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) GRIK1 CAH3CAH14 NR1H4 Antigen activates B Cell ReceptorGSTA2 (BCR) leading to generation of second messengers CBS CHL1 interactions B4GT1 HSF1 activationAmyloid fiber formation Synthesis of Leukotrienes (LT) and Eoxins (EX) Mitochondrial protein import CAH1 Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB CRMPs in Sema3A signaling AMPD3 HNMT Serine SC6A4biosynthesis Acyl chain remodeling of CL NEUR1 LIPC ST14CASPE KCC4 E2AK3CLEC7A/inflammasome pathway KLK14PRSS8 Defective CSF2RB causes pulmonary surfactantChondroitin metabolism sulfate biosynthesis dysfunction 5 (SMDP5) TKT ALBU FA10 ERN1 TGM1KLK5 Transport of inorganic cations/anions and amino acids/oligopeptides L13a-mediated translational silencing of CeruloplasminPTK6 Regulates expression RTKs and Their Effectors AKT1 and DOK1 MET receptor recycling Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Class B/2 (Secretin family receptors)MGAT2 PPOXTransport of bile salts BGLRand organicGalactose acids, catabolism metal ions and amine compounds GRIK4 S28A2 PMM2 FUT8 AOC1 GRIK5 S29A1S28A3 MPI ACOD FA12FA11 TRY1CTRB1 ERG7 Chylomicron assembly S22A3 Regulation of RUNX3 expression and activity Activation of Ca-permeableNTRK3 Kainate Receptor GGPPSFPPS VTDB TTHY BMP1 Invadopodia formation Ras activation uopn Ca2+ infux through NMDA receptor DGAT1 FA7 Relaxin receptors S22A4 ACACA GTR3Hedgehog 'off'Chylomicron state clearance APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway Thrombin signallingGlycogen through breakdown proteinase (glycogenolysis) activated receptors (PARs) Microtubule-dependentInsulin traffickingPLCG1 receptor ofevents connexons signalling Formationin ERBB2 from cascade signaling ofGolgi TC-NER to the Pre-Incisionplasma membrane Complex Reactions specific to the complex N-glycan synthesis pathway AbnormalNa+/Cl- conversion dependent of 2-oxoglutarate neurotransmitterAbacavir