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Amgen and Incyte – the Biotechnology Acquisition
Amgen and Incyte – the biotechnology acquisition Ana Carolina Coelho Student number: 152416013 Dissertation written under the supervision of António Luís Borges de Assunção Dissertation submitted in partial fulfilment of requirements for the MSc in Finance, at the Universidade Católica Portuguesa, May 2018 Abstract The main goal of this dissertation is to study the hypothesis of an acquisition in the biotechnology industry, between Amgen (acquirer) and Incyte (target). Amgen is a U.S.-based biotechnology company currently facing a decrease in sales, mainly due to an increase in the market share of generic drugs and the rise of biosimilar products. To offset the poor performance, it is looking for an acquisition in its industry, for which Incyte could be a suitable target. Incyte belongs to the U.S.-biotechnology industry, and although it has a shy presence in the market with only two released drugs, its revenues are expected to increase significantly in the near future. The combination of these companies would allow knowledge transfer about research and development process of new drugs, a stronger position in Europe, and a higher investment power to apply in R&D. The combined company would be able to decrease the number of employees due to duplication of jobs and decrease the cost of sales, as the power over suppliers increases. The potential synergies are valued at $28,522.8 million, of which $16,739.2 million are more likely to be realized. The combined firm, after the introduction of synergies, is expected to generate the same or even higher returns than the sum of the stand- alone businesses and higher growth rates, fulfilling Amgen’s need of growth. -
Kaufmann Large Cap Growths M a As of 3/31/21
Kaufmann Large Cap Growth SMA as of 3/31/21 Communication Services Activision Blizzard, Inc. Alphabet Inc. Facebook, Inc. Netflix, Inc. Pinterest, Inc. The Walt Disney Company T-Mobile US, Inc. Consumer Discretionary Airbnb, Inc. Alibaba Group Holding Limited - ADR Amazon.com, Inc. Coupang LLC Etsy, Inc. Floor & Decor Holdings, Inc. Home Depot, Inc. Las Vegas Sand Corp. lululemon athletica inc. MercadoLibre, Inc. NIKE, Inc. The TJX Companies, Inc. Consumer Staples Costco Wholesale Corporation Estee Lauder Cos., Inc., Class A Energy New Fortress Energy, Inc. Financials BlackRock, Inc. JPMorgan Chase & Co. KKR & Co., Inc Class COMMON MSCI Inc. The Goldman Sachs Group, Inc. Health Care Abbott Laboratories Alcon Inc. Alnylam Pharmaceuticals, Inc. Argenx SE - ADR Catalent, Inc. Charles River Laboratories International, Inc. Danaher Corp. Dexcom, Inc. Edwards Lifesciences Corporation Genmab A/S - ADR IDEXX Laboratories, Inc. Intuitive Surgical, Inc. Moderna, Inc. Sarepta Therapeutics, Inc. Stryker Corp. Ultragenyx Pharmaceutical, Inc. Veeva Systems Inc. Vertex Pharmaceuticals, Inc. Zai Lab Limited - ADR Zoetis Inc. Industrials CoStar Group, Inc. Generac Holdings, Inc. IHS Markit Ltd Roper Technologies, Inc. Trane Technologies Public Limited Company Verisk Analytics, Inc. Information Technology Advanced Micro Devices, Inc. Apple Inc. Coupa Software, Inc. Fidelity National Information Services, Inc. GDS Holdings Ltd.- ADR GoDaddy, Inc. Marvell Technology Group Ltd. Mastercard, Inc. Microsoft Corporation Nuance Communications, Inc. PagSeguro Digital Ltd. PayPal Holdings, Inc. Qualcomm, Inc. Qualtrics International, Inc. salesforce.com, inc. ServiceNow, Inc. Shopify, Inc. Splunk, Inc. Unity Software, Inc. Visa Inc. Workday, Inc. Materials Air Products and Chemicals, Inc. Ecolab Inc. Scotts Co. The Sherwin-Williams Company Real Estate Crown Castle International Corp. -
Securities at Value BT WALDEN MIDCAP FUND 31-Aug-21
Securities At Value BT WALDEN MIDCAP FUND 31-Aug-21 Ticker Description Shares/Par Market Value A US AGILENT TECHNOLOGIES INC 9,650.0000 1,693,285.50 AKAM US AKAMAI TECHNOLOGIES INC 8,650.0000 979,612.50 ARE US ALEXANDRIA REAL ESTATE EQ 4,675.0000 964,779.75 AME US AMETEK, INC. 7,350.0000 999,379.50 APH US AMPHENOL CORP - CLASS A 13,475.0000 1,032,589.25 ANSS US ANSYS INC 2,650.0000 968,204.00 ATR US APTARGROUP INC. 8,800.0000 1,186,240.00 AZPN US ASPEN TECHNOLOGY INC 11,025.0000 1,427,737.50 ATO US ATMOS ENERGY CORP 11,575.0000 1,128,678.25 AZO US AUTOZONE, INC. 875.0000 1,355,506.25 AVB US AVALONBAY COMMUNITIES INC 4,575.0000 1,050,328.50 AVY US AVERY DENNISON CORP 8,775.0000 1,977,797.25 BKR US BAKER HUGHES CO 85,800.0000 1,954,524.00 BR US BROADRIDGE FIN. SOLUTIONS 6,975.0000 1,201,234.50 BRO US BROWN & BROWN INC 18,825.0000 1,092,791.25 CBOE US CBOE GLOBAL MARKETS INC 10,400.0000 1,311,960.00 CRI US CARTER'S INC 15,150.0000 1,551,057.00 CERN US CERNER CORP. 13,200.0000 1,007,820.00 CHE US CHEMED CORPORATION 3,125.0000 1,489,687.50 CHD US CHURCH AND DWIGHT, INC 13,250.0000 1,108,495.00 CTXS US CITRIX SYSTEMS INC 10,425.0000 1,072,419.75 ED US CONSOLIDATED EDISON INC 16,350.0000 1,233,607.50 COO US COOPER COS 3,200.0000 1,442,272.00 CMI US CUMMINS INC 4,500.0000 1,061,910.00 CONE US CYRUSONE INC 9,875.0000 760,177.50 DCI US DONALDSON CO INC. -
Inozyme Pharma Expands Medical Leadership Team
Inozyme Pharma Expands Medical Leadership Team Strengthens Inozyme’s Ability to Advance Lead Candidate, INZ-701, into Clinical Trials Boston, Mass., Nov. 14, 2019 – Inozyme Pharma Inc., a biotechnology company developing novel medicines to treat rare and life-threatening mineralization disorders, today announced the addition of three industry veterans to its leadership team: • Pedro Huertas M.D., Ph.D., as Chief Medical Officer, • Gus Khursigara Ph.D., as Vice President of Medical Affairs and Clinical Operations, and • Catherine Nester, as Vice President of Physician and Patient Strategies. The executives will be instrumental in advancing Inozyme’s lead drug candidate, INZ-701, into clinical trials in 2020 for the treatment of patients with ENPP1 deficiency. INZ-701 is the first therapy that addresses the pathology of ENPP1 deficiency, including diseases such as generalized arterial calcification of infancy (GACI) type 1 and autosomal recessive hypophosphatemic rickets type 2 (ARHR2), both of which are rare and life-threatening manifestations of this enzyme deficiency. Inozyme Pharma received orphan drug designation for INZ-701 in the US and EU in 2018. “We are pleased and excited to welcome Pedro, Gus and Catherine to the Inozyme team,” said Axel Bolte, co-founder and chief executive officer of Inozyme. “Their expertise in orphan drug development – spanning medical affairs, regulatory affairs and clinical development – will strengthen and accelerate our ability to bring potentially life-saving medicines to people who urgently need effective treatments.” Dr. Huertas, a veteran of the pharmaceutical industry, has extensive experience in research and development and medical and regulatory affairs, especially regarding rare disorders and enzyme replacement therapies. -
Citi Pure Earnings Growth US Long-Short Net TR Index (CIISGRUN)
Date: 20-Aug-21 Index Weights as of monthly rebalance date 10-Aug-21 Citi Pure Earnings Growth US Long-Short Net TR Index (CIISGRUN) Long Exposure Short Exposure Constituent Bloomberg Ticker Constituent Name Weight(%) Constituent Bloomberg Ticker Constituent Name Weight(%) 1 AAP UN Equity Advance Auto Parts Inc 0.24% 1 A UN Equity Agilent Technologies Inc -0.12% 2 ABBV UN Equity AbbVie Inc. 0.59% 2 HWM UN Equity Alcoa Inc -1.02% 3 ABC UN Equity AmerisourceBergen Corp 0.06% 3 AAL UW Equity American Airlines Group Inc -1.09% 4 ADBE UW Equity Adobe Systems Inc 0.01% 4 AAPL UW Equity Apple Inc. -0.46% 5 ADM UN Equity Archer-Daniels-Midland Co 0.26% 5 ABMD UW Equity ABIOMED Inc -0.11% 6 ADSK UW Equity Autodesk Inc 0.26% 6 ABT UN Equity Abbott Laboratories -0.26% 7 AES UN Equity AES Corp 0.37% 7 CB UN Equity ACE Limited -0.07% 8 AIG UN Equity American Intl Group Inc 0.52% 8 ACN UN Equity Accenture plc -0.29% 9 AIZ UN Equity Assurant Inc 0.11% 9 ADI UW Equity Analog Devices Inc -0.13% 10 ALGN UW Equity Align Technology Inc 0.59% 10 ADP UW Equity Automatic Data Processing -0.76% 11 ALL UN Equity Allstate Corp 0.16% 11 AEE UN Equity Ameren Corp -0.24% 12 ALLE UN Equity Allegion PLC 0.34% 12 AEP UW Equity American Electric Power -0.23% 13 AMAT UW Equity Applied Materials Inc 0.59% 13 AFL UN Equity AFLAC Inc -0.29% 14 AMD UW Equity Advanced Micro Devices Inc 1.15% 14 AJG UN Equity ARTHUR J GALLAGHER & CO -0.23% 15 AME UN Equity AMETEK Inc 0.26% 15 AKAM UW Equity Akamai Technologies Inc -0.11% 16 AMT UN Equity American Tower Corp A 0.39% 16 ALB UN -
2020 Q1 Sawgrass FF
Investment Statement June 30, 2021 Ormond Beach Firefighters Pension Trust Fund Diversified Large Growth Equity Gregory S. Gosch, Institutional Client Services (904) 493-5506 1579 The Greens Way, Suite 20 Jacksonville Beach, FL 32250 www.saw-grass.com Portfolio Review Portfolio Market Values Portfolio Summary Change in Portfolio Market Value Asset Class Total Cost Market Value Percent of Assets Beginning Market Value on 03/31/2021 $4,321,633.21 Equity $2,683,259.40 $4,518,862.64 98.3% Additions $0.00 Cash & Equivs. $77,110.59 $77,110.59 1.7% Withdrawals -$30,353.69 TOTAL $2,760,369.99 $4,595,973.23 100% Investment Gain/Loss $310,432.01 Ending Market Value on 06/30/2021 $4,595,973.23 Asset Allocation Equity Cash & Equivs. 98% 2% STABILITY | CONSISTENCY | COMMITMENT 2 Portfolio Performance TOTAL RETURNS FOR SELECT PERIODS Ormond Beach Firefighters Pension Trust Fund 06/30/2021 Quarter Year Latest Latest Latest Latest Since To Date To Date One Year Three Year Five Year Ten Year Inception* Total Account 7.19 11.32 31.15 21.03 18.39 - 15.87 Russell 1000 Growth 11.93 12.99 42.50 25.14 23.66 - 18.44 Equities 7.25 11.43 31.54 21.71 19.07 - 16.52 Russell 1000 Growth 11.93 12.99 42.50 25.14 23.66 - 18.44 S&P 500 8.55 15.25 40.79 18.67 17.65 - 15.39 Fixed Income - - - - - - - Cash and Equiv. - - - 1.03 0.90 - 0.54 Other - - - - - - - *Since Inception 04/25/12 Performance is Gross of Fees unless otherwise noted Returns for periods of one year or longer are annualized STABILITY | CONSISTENCY | COMMITMENT 3 Portfolio Performance TOTAL RETURNS GROSS FOR SELECT PERIODS Ormond Beach Firefighters Pension Trust Fund 06/30/2021 45.0% 40.0% 35.0% 30.0% 25.0% 20.0% 15.0% 10.0% 5.0% 0.0% QTD YTD 1 Year 3 Year 5 Year Since Inception Portfolio Russell 1000 Growth *Since Inception 04/25/12 Returns for periods of one year or longer are annualized STABILITY | CONSISTENCY | COMMITMENT 4 Portfolio Holdings Security Quantity Unit Cost Total Cost Price Market Value Pct of Assets Common Stock Consumer Discretionary TRACTOR SUPPLY CO COM 369.00 149.35 55,109.22 186.06 68,656.14 1.5 NIKE INC. -
Incyte Corporation 2016 Annual Report
2016 ANNUAL REPORT TABLE OF CONTENTS Letter to Shareholders 2 Key Planned Goals for 2017 6 Innovation 7 Growth 10 Strength 13 Corporate Responsibility 15 Company Information 19 ii Incyte’s Executive Management Team LETTER TO SHAREHOLDERS Standing, left to right: Steven H. Stein, MD; Dear Shareholders, Paula J. Swain; Wenqing Yao, PhD; Jonathan E. Dickinson; At Incyte, we believe that innovation and the discovery of new products David W. Gryska; creates long-term value for patients and society, as well as for our employ- Hervé Hoppenot; Michael Morrissey; ees and our shareholders. It is our commitment to these objectives that has Vijay Iyengar, MD enabled us to make significant progress in the last year. During 2016, we saw continued growth in the number of patients being treated with Jakafi® Seated, left to right: Eric H. Siegel, JD, MBA; (ruxolitinib), our JAK1/JAK2 inhibitor, and we also added Iclusig® (ponati- Reid M. Huber, PhD; nib) to our commercial portfolio as part of our European transaction with Barry P. Flannelly, PharmD, MBA ARIAD Pharmaceuticals, Inc. In February 2017, with Eli Lilly & Company, we announced the European approval of Olumiant® (baricitinib). I believe that we are on Summary of Revenue-Generating Products track to reach our goal of PRODUCT NAME DRUG NAME TARGET APPROVED TERRITORY INDICATION(S) becoming a world-class, Jakafi® ruxolitinib1 JAK1/JAK2 Global MF3; PV4 Jakavi® global biopharmaceutical organization. For the first Iclusig® ponatinib BCR-ABL Europe CML and Ph+ ALL5 time in the history of our company, Incyte’s total Olumiant® baricitinib2 JAK1/JAK2 Europe RA6 yearly revenue surpassed $1 billion in 2016. -
Massmutual Mid Cap Growth Fund T
Fund Holdings As of 06/30/2021 MassMutual Mid Cap Growth Fund T. Rowe Price | Frontier Capital Prior to 5/1/2021, the Fund name was MassMutual Select Mid Cap Growth Fund. Fund Shares or Par Position Market Security Name Ticker CUSIP Weighting (%) Amount Value ($) Microchip Technology Inc MCHP 595017104 2.07 1,348,381 201,906,571 Agilent Technologies Inc A 00846U101 1.90 1,252,717 185,164,100 Hologic Inc HOLX 436440101 1.84 2,678,942 178,739,010 Teleflex Inc TFX 879369106 1.82 441,297 177,308,722 Ball Corp BLL 058498106 1.75 2,104,895 170,538,593 Textron Inc TXT 883203101 1.55 2,199,000 151,225,230 Burlington Stores Inc BURL 122017106 1.54 465,929 150,024,479 Catalent Inc CTLT 148806102 1.53 1,376,000 148,773,120 Marvell Technology Inc MRVL 573874104 1.46 2,442,368 142,463,325 Bruker Corp BRKR 116794108 1.39 1,776,000 134,940,480 Ingersoll Rand Inc IR 45687V106 1.29 2,564,000 125,148,840 The Cooper Companies Inc COO 216648402 1.28 314,645 124,684,374 KKR & Co Inc Ordinary Shares KKR 48251W104 1.25 2,050,813 121,490,162 Caesars Entertainment Inc CZR 12769G100 1.13 1,057,315 109,696,431 Reserve Invt Fds 0 76105Y208 1.07 103,877,547 103,877,547 DocuSign Inc DOCU 256163106 1.05 366,000 102,322,620 Chipotle Mexican Grill Inc CMG 169656105 1.04 65,283 101,210,846 Dollar General Corp DG 256677105 1.02 460,009 99,541,348 Veeva Systems Inc Class A VEEV 922475108 1.00 314,189 97,697,070 Avantor Inc AVTR 05352A100 0.98 2,700,000 95,877,000 JB Hunt Transport Services Inc JBHT 445658107 0.98 585,000 95,325,750 KLA Corp KLAC 482480100 0.97 291,710 94,575,299 -
CDER – Redi: Focus on CGMP & FDA Inspections – Participant List
FDA – CDER – RedI: Focus on CGMP & FDA Inspections – Participant List These participants granted permission to share their contact information Eileen Zhou Michael Channing A B M Mahfuz ul Alam Research Associate Group Chief - Positron Emission General Manager, Quality Operations Neuralstem Tomography Department ACI HealthCare Limited Germantown, MD, United States NIH Dhaka, Non-US, Bangladesh [email protected] Bethesda, MD, United States [email protected] [email protected] Abe Wong ABHIJEET GUJAR Adam Ebbinghouse CCO Chief Operating Officer QC Associate Gmpsigma SETHU KP Pharmaceutical Technology, Inc. Seattle, WA, United States Porvorim Goa, Non-US, India Bloomington, IN, United States [email protected] [email protected] [email protected] Adil Gatrad Adiseshu Modugula Aditiben Patel Director, Quality Systems RA Regulatory Specialist Actavis MSN USAMMDA Parsippany, NJ, United States Hyderabad, Non-US, India Frederick, MD, United States [email protected] [email protected] [email protected] Adriana de la Cruz ahsanul haque Aimee Gogarty Manager CSO Quality Coordinator Laboratorios Pisa SA de CV FDA Mallinckrodt Jalisco, Non-US, Mexico silver spring, MD, United States Port Allen, LA, United States [email protected] [email protected] [email protected] Aislyn Fronzak Ajay Deshmukh Ajay Khedkar QC Manager QA manager Regulatory Affair PL Developments Ingenus Pharmaceutical Umedica Laboratories Pvt Ltd Clinton, SC, United States Navi mumbai, Non-US, India Mumbai, Non-US, India [email protected] -
Companies in Attendance
COMPANIES IN ATTENDANCE Abbott Diabetes Care Archbow Consulting LLC Business One Technologies Abbott Laboratories ARKRAY USA BusinessOneTech AbbVie Armory Hill Advocates, LLC CastiaRX ACADIA Artia Solutions Catalyst Acaria Health Asembia Celgene Accredo Assertio Therapeutics Celltrion Acer Therapeutics AssistRx Center for Creative Leadership Acorda Therapeutics Astellas Pharma US Inc. Cigna Actelion AstraZeneca Cigna Specialty Pharmacy AdhereTech Athenex Oncology Circassia Advantage Point Solutions Avanir Coeus Consulting Group Aerie Pharmaceuticals Avella Coherus Biosciences AGIOS AveXis Collaborative Associates LLC Aimmune Theraputics Bank of America Collegium Akcea Therapeutics Bausch Health Corsica Life Sciences Akebia Therapeutics Bayer U.S. CoverMyMeds Alder BioPharmaceuticals Becton Dickinson Creehan & Company, Inc., an Inovalon Company Alexion Biofrontera CSL Behring Alkermes Biogen Curant Health Allergan Biohaven CVS Health Almirall BioMarin D2 Consulting Alnylam BioMatrix Specialty Pharmacy Daiichi Sankyo Amarin BioPlus Specialty Pharmacy DBV Technologies Amber Pharmacy Bioventus Deloitte Consulting LLP AmerisourceBergen Blue Cross Blue Shield Association Dendreon Amgen Blue Fin Group Dermira Amicus Therapeutics bluebird bio Dexcom Amneal Boehringer Ingelheim Diplomat Pharmacy Anthem Boston Biomedical Dova Applied Policy Bowler and Company Decision Resources Group Aquestive Therapeutics Braeburn Eisai Arbor Pharmaceuticals Bristol-Myers Squibb 1 electroCore Indivior Merz Pharmaceuticals EMD Serono Inside Rx Milliman Encore Dermatology, -
Mainstay WMC Enduring Capital Fund Q1 Holdings
MainStay MacKay Common Stock Fund Portfolio of Investments January 31, 2021† (Unaudited) Shares Value Common Stocks 98.2% Aerospace & Defense 2.0% Boeing Co. (The) 2,259 $ 438,675 Huntington Ingalls Industries, Inc. 5,380 846,435 Lockheed Martin Corp. 1,121 360,760 Northrop Grumman Corp. 342 98,021 Raytheon Technologies Corp. 6,466 431,476 Textron, Inc. 13,660 618,252 2,793,619 Air Freight & Logistics 0.7% FedEx Corp. 2,381 560,345 United Parcel Service, Inc., Class B 2,108 326,740 887,085 Auto Components 0.1% Aptiv plc 1,149 153,506 Automobiles 1.5% (a) Tesla, Inc. 2,563 2,033,817 Banks 3.6% Bank of America Corp. 14,882 441,251 Comerica, Inc. 14,415 824,538 Fifth Third Bancorp 19,190 555,167 JPMorgan Chase & Co. 5,995 771,377 Signature Bank 5,330 880,463 Synovus Financial Corp. 26,791 996,625 Truist Financial Corp. 10,429 500,383 4,969,804 Beverages 0.2% Coca-Cola Co. (The) 150 7,222 Molson Coors Beverage Co., Class B 3,023 151,634 PepsiCo, Inc. 897 122,503 281,359 Biotechnology 4.4% AbbVie, Inc. 6,231 638,553 Amgen, Inc. 5,750 1,388,222 Biogen, Inc. (a) 4,125 1,165,766 Exelixis, Inc. (a) 2,353 52,260 Gilead Sciences, Inc. 20,056 1,315,674 Incyte Corp. (a) 4,144 371,924 Regeneron Pharmaceuticals, Inc. (a) 751 378,384 United Therapeutics Corp. (a) 4,636 759,470 6,070,253 Building Products 0.6% Carrier Global Corp. -
MS in Business Analytics Internship Statistics 2018-2019
MS in Business Analytics Internship Statistics 2018-2019 2018 – 2019 Academic Year Fall Spring Summer Total/Avg 2018 – Statistic 2018 2019 2019 2019 Number of Internships 165 171 252 588 Reported Average Hourly Salary $21.50 $23.05 $22.89 $22.55 Average Number of 35 35 39 36 Hours/Week % of Internships in Texas 65% 65% 55% 62% # of Internships Abroad 2 1 2 5 Company Company Company 4front Equifax OCC (Options Clearing Corporation) A&G LLP Ericsson Octane Lending AArete ERP Logic LLC Office of Information Technology, The University of Texas at Dallas Accufire Technology Inc. Essilor One Technologies Acuity Eye Care Group Essilor of America Inc. OneMagnify Adaptive3D Technologies LLC Exela Technologies Options Clearing Corporation Addison Health Systems Inc. Experis Oracle Page 1 of 5 Aditi Consulting e-Zest Solutions Inc. OrderMyGear Aditi Staffing EZLynx Oriental Trading Company Adobe Systems Fathomd Inc. Parks Associates Advatix Federal Reserve Bank of Dallas PepsiCo Aeris Communications FedEx Services Perot Museum of Nature and Science AG Technologies FHL Bank Dallas Peterbilt Motors Company Agilent Technologies Finastra PMG Albertsons Companies Fiserv Polytronix Inc. Allegiant Travel Company Five Point Five Solutions (Tesser Populus Group LLC Insights) Allegis Group FleetPride Inc. Presbyterian Healthcare Services Allied Stone Inc. Flipt PricewaterhouseCoopers (PwC) Ally Financial Fortech Energy Inc. Primary Services LP ALM First Financial Advisors LLC Fossil Group Prime Medstaff LLC Alpha Business Images FourPoint Energy LLC Primus Global Services Inc. American Airlines Fresenius Medical Care Priority Health American College of Emergency Fresenius Medical Care North Priority Health Physicians America American Heart Association Frontdoor Pro Unlimited Inc.