Pmconfprog1 (Page 1)
Total Page:16
File Type:pdf, Size:1020Kb
Personalized Medicine: Promises and Prospects A Conference Hosted By HARVARD MEDICAL SCHOOL – PARTNERS HEALTHCARE CENTER FOR GENETICS AND GENOMICS November 3-4, 2005 The Conference Center Harvard Medical School Boston, Massachusetts Conference Program November 3, 2005 Dear Colleague, It is my pleasure to welcome you to Personalized Medicine: Promises and Prospects. The past few years have witnessed a revolution in the understanding of health and dis- ease, brought on by the sequencing of the human genome and the creation of a map of human genetic variation. It is now becoming possible to translate this knowledge to patient care. The ability to use genetic and genomic information in diagnosis, prognosis and treatment has been given a name: personalized medicine. The goal of personalized medicine is to provide the right diagnosis and treatment to the right patient at the right time at the right cost. Hosted by the Harvard Medical School – Partners Healthcare Center for Genetics and Genomics (HPCGG) the conference will focus on the perspectives of Government, Pharmaceutical, Academic, and Diagnostic leaders as well as those of healthcare providers and payers in implementing the new paradigm of personalized medicine. The program will feature several personalized medicine case studies on topics such as lung cancer and cardiovascular disease and will highlight the information technology infra- structure needed to make personalized medicine a reality. The tone for the conference will be one that will explore what happens "on the ground" when personalized medicine is put into practice, and what that means for caregivers, patients and payers, as well as for the industries that develop products for personalized medicine. Formed in 2001, the HPCGG is a joint venture between Harvard Medical School and Partners Healthcare, including its founding members Massachusetts General Hospital and Brigham and Women’s Hospital. The Center’s mission is to integrate genetics and genomics into the practice of medicine. It is involved in the full spectrum of genetics and genomics activities, including basic research, clinical research, core services for researchers, molecular-based diagnostic testing, clinical care and training and education. I would like to take this opportunity to thank the members of our organizing committee for all of their hard work in planning the conference; our speakers for their willingness to share their thoughts and plans on this exciting topic; and the program’s sponsors, whose support allows today’s conference to become a reality. This is truly an exciting time for medicine and I am delighted you have decided to join us. Sincerely, Raju Kucherlapati, Ph.D. Scientific Director of Harvard-Partners Center for Genetics and Genomics Sponsors The Harvard – Partners Center for Genetics and Genomics would like to thank the sponsors of this event for their generous support. GOLD SILVER EDUCATIONAL BRONZE VIDEO ARCHIVES 4 HARVARD MEDICAL SCHOOL - PARTNERS HEALTHCARE CENTER FOR GENETICS AND GENOMICS Conference Organizing Committee Raju Kucherlapati, Ph.D. Mason Freeman, M.D., Ph.D. Scientifc Director of Harvard-Partners Translational Medicine Head for Center for Genetics and Genomics Cardiovascular and Metabolism, Paul C. Cabot Professor of Genetics, Novartis Institute for Biomedical Research Harvard Medical School David Ginsburg, M.D. Edward Abrahams, Ph.D. Chief, Division of Medical Genetics Executive Director Professor of Internal Medicine and Human Genetics Personalized Medicine Coalition University of Michigan Mara G. Aspinall Geoffrey Ginsburg, M.D., Ph.D. President, Genetics Director, Center for Genomic Medicine Genzyme Corporation Duke University Abbie Celniker, Ph.D. Marcia A. Kean Senior Vice President, Chief Executive Officer Research and Development Strategy Feinstein Kean Heathcare and Operations Millenium Pharmaceuticals Daniel K. Podolsky, M.D. Chief Academic Officer William F. Crowley Jr., M.D. Partners HealthCare System Chief, Reproductive Endocrine Unit; Director, Clinical Research Program Hakan Sakul, Ph.D. Massachusetts General Hospital Director and Site Head, Clinical Pharmacogenomics-Groton Laboratories Pfizer Global R & D Harvard-Partners Center for Genetics and Genomics Labs at 65 Landsdowne Street, Cambridge PERSONALIZED MEDICINE: PROMISES AND PROSPECTS 5 Conference Program Thursday, November 3, 2005 TIME TOPIC SPEAKER / MODERATOR 7:30-8:45 Registration & Continental Breakfast 8:45 Welcome Daniel Podolsky, MD, Chief Academic Officer, Partners HealthCare System 9:00-12:00 Session I – Session Moderator: Raju Kucherlapati, PhD, Perspectives on Scientific Director, Harvard-Partners Center Personalized Medicine for Genetics and Genomics, Paul C. Cabot Professor of Genetics, Harvard Medical School 9:00 Societal Impact of Reed V. Tuckson, MD, FACP, Senior Vice President, Consumer Personalized Medicine Health and Medical Care Advancement, UnitedHealth Group 9:30 Personalized Medicine Declan P. Doogan, MD, Senior Vice President, Head of and Drug Development Worldwide Development, Pfizer Global Research & Development 10:00 Prospective Medicine: Ralph Snyderman, MD, Chancellor Emeritus, Duke University The Next Health Care Transformation 10:30 The Right Test for the Mara Aspinall, President, Genetics, Genzyme Corporation Right Patient at the Right Time – The Crucial Role of Diagnostics in Personalized Medicine 11:00 Panel All Four Speakers 11:30 Lunch e-Salon open with Wi-Fi 6 HARVARD MEDICAL SCHOOL - PARTNERS HEALTHCARE CENTER FOR GENETICS AND GENOMICS Thursday, November 3, 2005 TIME TOPIC SPEAKER / MODERATOR 12:30-4:00 Session II – Case Studies Session Moderator: Cynthia Morton, PhD, William Lambert Richardson Professor of Obstetrics, Gynecology and Reproductive Biology and Professor of Pathology, Harvard Medical School; Director of Cytogenetics, Brigham and Women’s Hospital 12:30 Managing Bleeding and David Ginsburg, MD, James V. Neel Distinguished University Clotting in the 21st Century Professor, Departments of Internal Medicine & Human Genetics, Investigator, Howard Hughes Medical Institute, University of Michigan 1:00 Targeted Medicine Eric J. Topol, MD, Provost, Cleveland Clinic Lerner College of for Heart Attack? Medicine; Professor of Medicine & Genetics, Case Western Reserve University 1:30 Molecular Targeting Daniel A. Haber, MD, PhD, Director of the MGH Cancer Center, of Lung Cancer Massachusetts General Hospital 2:00 Pediatric Genetic Testing David Valle, MD, Professor of Pediatrics, Molecular Biology and Genetics, Johns Hopkins University, School of Medicine 2:30 Development of Targeted John Hohneker, MD, Vice President, US Medical Affairs and Therapies - Gleevec Services, Oncology, Novartis Pharmaceuticals Corporation 3:00 Break e-Salon open with Wi-Fi 3:30 The Business of Personalized Deborah Dunsire, MD, Chief Executive Officer, Medicine: Delivering Better Millennium Pharmaceuticals, Inc. Therapies to Patients 4:00-5:00 Session III – Session Moderator: Katherine A. Schneider, MPH, CGC, Training & Education Senior Genetic Counselor, Dana-Farber Cancer Institute 4:00 Integration of Genetics into Bruce Korf, MD, PhD, Wayne M. and Sara Crews Finley Medical Practice: Professor of Medical Genetics, Chair, Department of Genetics, Educational Challenges University of Alabama at Birmingham 4:30 Role of Government in Sharon F. Terry, MA, President and CEO, Genetic Alliance Personalized Medicine 5:00-7:00 Cocktail Reception & • “PMC 2005 Leadership in Personalized Medicine Award”, PMC Award Presentation presented by Edward Abrahams, Ph.D., Executive Director, PMC • e-Salon open with Wi-Fi Dinner on your own PERSONALIZED MEDICINE: PROMISES AND PROSPECTS 7 Conference Program continued Friday, November 4, 2005 TIME TOPIC SPEAKER / MODERATOR 7:30-8:30 Continental Breakfast e-Salon open at 8:00 with Wi-Fi 8:30-12:00 Session IV: Session Moderator: John Glaser, Ph.D., Vice President and Information Technology Chief Information Officer, Partners HealthCare System 8:30 Privacy and Security Robert J. Mandel, MD, Chief Operating Officer, Requirements of the EMR Massachusetts eHealth Collaborative – Experiences from the Massachusetts eHealth Collaborative 8:55 Information Based Medicine: Michael E. Svinte,Vice President, Information Based Medicine Innovation in Patient Care EBO, IBM Healthcare and Life Sciences 9:20 Personalized Medicine: Jeff Miller, Vice President, Worldwide Health and Life Sciences, Creating the Foundation Hewlett-Packard of Promise 9:45 Role of the EMR in Carol C. Diamond, MD, MPH, Managing Director of Personalized Medicine Healthcare Program, The Markle Foundation 10:10 Break e-Salon open with Wi-Fi 10:40 Panel Discussion All four Speakers 11:20 The Decade of Health David J. Brailer, MD, PhD, National Coordinator for Health Information Technology Information Technology, U.S. Department of Health and Human Services 11:50 Closing Comments Raju Kucherlapati, PhD, Scientific Director, Harvard-Partners Center for Genetics and Genomics, Paul C. Cabot Professor of Genetics, Harvard Medical School 12:00 Box Lunch 8 HARVARD MEDICAL SCHOOL - PARTNERS HEALTHCARE CENTER FOR GENETICS AND GENOMICS Conference Speakers Mara Aspinall completed his medical residency at the Hospital of the Mara Aspinall joined Genzyme in 1997. She is responsible for University of Pennsylvania and became board certified in inter- the Genzyme Genetics business unit, which includes nine lab- nal medicine along the clinical investigator pathway. Dr. Brailer oratories across the United States and operations in Japan. was a Robert Wood Johnson